Incidental Mutation 'R7384:Gcc2'
| ID |
572960 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gcc2
|
| Ensembl Gene |
ENSMUSG00000038039 |
| Gene Name |
GRIP and coiled-coil domain containing 2 |
| Synonyms |
0610043A03Rik, 2210420P05Rik, 2600014C01Rik |
| MMRRC Submission |
045466-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.187)
|
| Stock # |
R7384 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
58091319-58141421 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 58105786 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 341
(S341T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000054033
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057659]
[ENSMUST00000160416]
[ENSMUST00000160427]
[ENSMUST00000162041]
[ENSMUST00000162860]
[ENSMUST00000162984]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000057659
AA Change: S341T
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000054033
Gene: ENSMUSG00000038039
AA Change: S341T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
14 |
N/A |
INTRINSIC |
|
coiled coil region
|
33 |
282 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
353 |
378 |
3.94e-5 |
PROSPERO |
|
internal_repeat_2
|
382 |
406 |
3.94e-5 |
PROSPERO |
|
coiled coil region
|
790 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
939 |
964 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1093 |
1111 |
1.93e-5 |
PROSPERO |
|
low complexity region
|
1115 |
1132 |
N/A |
INTRINSIC |
|
low complexity region
|
1179 |
1190 |
N/A |
INTRINSIC |
|
coiled coil region
|
1441 |
1470 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1554 |
1572 |
1.93e-5 |
PROSPERO |
|
Grip
|
1608 |
1655 |
4.37e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160416
|
| SMART Domains |
Protein: ENSMUSP00000123873
Gene: ENSMUSG00000038039
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
37 |
176 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160427
|
| SMART Domains |
Protein: ENSMUSP00000124411
Gene: ENSMUSG00000038039
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
32 |
94 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162041
AA Change: S305T
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000124787
Gene: ENSMUSG00000038039
AA Change: S305T
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
32 |
246 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
317 |
342 |
3.28e-5 |
PROSPERO |
|
internal_repeat_2
|
346 |
370 |
3.28e-5 |
PROSPERO |
|
coiled coil region
|
754 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
928 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1057 |
1075 |
1.6e-5 |
PROSPERO |
|
low complexity region
|
1079 |
1096 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1154 |
N/A |
INTRINSIC |
|
coiled coil region
|
1405 |
1434 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1518 |
1536 |
1.6e-5 |
PROSPERO |
|
Grip
|
1572 |
1619 |
4.37e-19 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162860
AA Change: S241T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000124152
Gene: ENSMUSG00000038039
AA Change: S241T
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
46 |
182 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
253 |
278 |
4.17e-5 |
PROSPERO |
|
internal_repeat_2
|
282 |
306 |
4.17e-5 |
PROSPERO |
|
coiled coil region
|
690 |
782 |
N/A |
INTRINSIC |
|
low complexity region
|
839 |
864 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
993 |
1011 |
2.06e-5 |
PROSPERO |
|
low complexity region
|
1015 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
coiled coil region
|
1341 |
1370 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1450 |
1468 |
2.06e-5 |
PROSPERO |
|
Grip
|
1504 |
1551 |
4.37e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162984
|
| SMART Domains |
Protein: ENSMUSP00000124988
Gene: ENSMUSG00000038039
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
14 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a peripheral membrane protein localized to the trans-Golgi network. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm5 |
T |
A |
4: 144,507,191 (GRCm39) |
I65F |
possibly damaging |
Het |
| Abca13 |
C |
A |
11: 9,283,257 (GRCm39) |
S3226R |
probably damaging |
Het |
| Abhd14b |
A |
G |
9: 106,327,340 (GRCm39) |
I41V |
probably benign |
Het |
| Acot2 |
T |
C |
12: 84,039,441 (GRCm39) |
S317P |
probably benign |
Het |
| Acp7 |
T |
C |
7: 28,314,513 (GRCm39) |
E284G |
possibly damaging |
Het |
| Adamts5 |
A |
G |
16: 85,696,714 (GRCm39) |
F148L |
probably benign |
Het |
| Adcy10 |
C |
T |
1: 165,404,177 (GRCm39) |
P1611S |
unknown |
Het |
| Agr2 |
A |
G |
12: 36,045,923 (GRCm39) |
T57A |
probably damaging |
Het |
| Ankar |
T |
G |
1: 72,697,624 (GRCm39) |
I1060L |
probably benign |
Het |
| Ano10 |
T |
A |
9: 122,005,409 (GRCm39) |
D77V |
unknown |
Het |
| Anxa2r1 |
T |
A |
13: 120,496,797 (GRCm39) |
Q24L |
possibly damaging |
Het |
| Apc2 |
G |
A |
10: 80,148,458 (GRCm39) |
V1171I |
probably damaging |
Het |
| Apoa4 |
G |
A |
9: 46,152,772 (GRCm39) |
R19Q |
not run |
Het |
| Arhgap33 |
A |
G |
7: 30,226,696 (GRCm39) |
S504P |
probably damaging |
Het |
| Atg2a |
T |
C |
19: 6,311,707 (GRCm39) |
V1862A |
probably damaging |
Het |
| Atp7b |
T |
C |
8: 22,512,331 (GRCm39) |
S511G |
probably benign |
Het |
| Bcl10 |
A |
G |
3: 145,638,795 (GRCm39) |
K146E |
possibly damaging |
Het |
| Bsg |
A |
T |
10: 79,545,631 (GRCm39) |
D181V |
probably damaging |
Het |
| Btg4 |
T |
C |
9: 51,030,413 (GRCm39) |
V171A |
probably benign |
Het |
| Cdh8 |
A |
C |
8: 99,957,138 (GRCm39) |
N188K |
probably benign |
Het |
| Cflar |
C |
A |
1: 58,791,735 (GRCm39) |
T346K |
|
Het |
| Chrna5 |
T |
C |
9: 54,912,117 (GRCm39) |
S306P |
probably damaging |
Het |
| Cldn20 |
G |
A |
17: 3,582,886 (GRCm39) |
G20R |
probably damaging |
Het |
| Clns1a |
G |
A |
7: 97,345,988 (GRCm39) |
A18T |
probably benign |
Het |
| D130043K22Rik |
A |
G |
13: 25,066,588 (GRCm39) |
Y795C |
probably damaging |
Het |
| Dync1li2 |
A |
C |
8: 105,169,175 (GRCm39) |
S38A |
probably benign |
Het |
| Dysf |
A |
G |
6: 84,091,087 (GRCm39) |
E1043G |
probably benign |
Het |
| Elapor1 |
A |
T |
3: 108,370,784 (GRCm39) |
|
probably null |
Het |
| Eral1 |
A |
G |
11: 77,964,927 (GRCm39) |
I422T |
possibly damaging |
Het |
| Exoc3 |
G |
A |
13: 74,320,275 (GRCm39) |
P729S |
probably benign |
Het |
| Eya1 |
T |
A |
1: 14,299,736 (GRCm39) |
Y339F |
probably damaging |
Het |
| Faah |
G |
T |
4: 115,862,364 (GRCm39) |
N206K |
probably damaging |
Het |
| Fem1a |
A |
G |
17: 56,564,537 (GRCm39) |
E210G |
probably benign |
Het |
| Gfpt2 |
A |
T |
11: 49,701,817 (GRCm39) |
I123F |
possibly damaging |
Het |
| Gm3047 |
T |
A |
14: 4,558,271 (GRCm38) |
N164K |
probably damaging |
Het |
| Gm3327 |
A |
G |
14: 44,362,334 (GRCm39) |
K78E |
|
Het |
| Herpud1 |
A |
G |
8: 95,116,005 (GRCm39) |
I57V |
probably damaging |
Het |
| Homer1 |
A |
T |
13: 93,529,547 (GRCm39) |
R285S |
possibly damaging |
Het |
| Hps6 |
T |
A |
19: 45,992,456 (GRCm39) |
V131E |
possibly damaging |
Het |
| Il1r1 |
T |
A |
1: 40,321,421 (GRCm39) |
I11N |
possibly damaging |
Het |
| Jakmip1 |
T |
A |
5: 37,330,551 (GRCm39) |
D410E |
possibly damaging |
Het |
| Kif3a |
T |
A |
11: 53,469,681 (GRCm39) |
F97L |
probably damaging |
Het |
| Klf11 |
C |
T |
12: 24,703,742 (GRCm39) |
T76I |
probably damaging |
Het |
| Ldlr |
A |
C |
9: 21,651,090 (GRCm39) |
T503P |
probably benign |
Het |
| Mapk3 |
G |
C |
7: 126,363,463 (GRCm39) |
R279P |
|
Het |
| Mb21d2 |
A |
T |
16: 28,647,664 (GRCm39) |
D103E |
probably benign |
Het |
| Msh4 |
T |
A |
3: 153,594,385 (GRCm39) |
M333L |
probably benign |
Het |
| Mycbp2 |
A |
G |
14: 103,513,829 (GRCm39) |
I836T |
probably damaging |
Het |
| Myh1 |
A |
T |
11: 67,115,201 (GRCm39) |
E1912V |
possibly damaging |
Het |
| Ncapd2 |
A |
G |
6: 125,150,364 (GRCm39) |
V887A |
probably benign |
Het |
| Nlrp4a |
G |
A |
7: 26,148,963 (GRCm39) |
R190Q |
not run |
Het |
| Nop53 |
T |
C |
7: 15,673,420 (GRCm39) |
T344A |
probably damaging |
Het |
| Or2r3 |
A |
T |
6: 42,448,257 (GRCm39) |
L285Q |
possibly damaging |
Het |
| Or5an11 |
T |
C |
19: 12,246,440 (GRCm39) |
V282A |
possibly damaging |
Het |
| Or7h8 |
A |
G |
9: 20,124,041 (GRCm39) |
Y132C |
probably damaging |
Het |
| Pcyox1l |
A |
C |
18: 61,831,461 (GRCm39) |
V266G |
probably damaging |
Het |
| Pde5a |
A |
G |
3: 122,618,649 (GRCm39) |
Y654C |
probably damaging |
Het |
| Polq |
T |
C |
16: 36,849,780 (GRCm39) |
S345P |
probably damaging |
Het |
| Polr1f |
G |
T |
12: 33,483,631 (GRCm39) |
G128W |
probably damaging |
Het |
| Prdm1 |
A |
T |
10: 44,334,503 (GRCm39) |
C8S |
probably benign |
Het |
| Psg17 |
T |
A |
7: 18,552,585 (GRCm39) |
Q230L |
possibly damaging |
Het |
| Rab11fip5 |
A |
T |
6: 85,325,312 (GRCm39) |
S332T |
possibly damaging |
Het |
| Rac2 |
T |
A |
15: 78,446,131 (GRCm39) |
K186* |
probably null |
Het |
| S100pbp |
T |
C |
4: 129,075,702 (GRCm39) |
N208D |
probably benign |
Het |
| Scaf11 |
A |
T |
15: 96,318,268 (GRCm39) |
V432D |
possibly damaging |
Het |
| Skic3 |
A |
C |
13: 76,298,854 (GRCm39) |
S1187R |
possibly damaging |
Het |
| Slc34a1 |
G |
T |
13: 55,550,747 (GRCm39) |
C225F |
probably benign |
Het |
| Slc35e2 |
A |
T |
4: 155,695,089 (GRCm39) |
M152L |
probably benign |
Het |
| Slc49a3 |
A |
T |
5: 108,593,926 (GRCm39) |
I61K |
probably damaging |
Het |
| Slc9a4 |
T |
A |
1: 40,651,411 (GRCm39) |
I563K |
probably benign |
Het |
| Sppl3 |
T |
G |
5: 115,199,700 (GRCm39) |
|
probably null |
Het |
| Stam |
T |
C |
2: 14,139,241 (GRCm39) |
F301L |
probably benign |
Het |
| Supt16 |
G |
A |
14: 52,418,619 (GRCm39) |
R213W |
probably damaging |
Het |
| Tbc1d8 |
A |
T |
1: 39,433,179 (GRCm39) |
D334E |
probably benign |
Het |
| Tmem87a |
C |
T |
2: 120,202,004 (GRCm39) |
|
probably null |
Het |
| Tnk1 |
T |
C |
11: 69,742,447 (GRCm39) |
Y661C |
probably damaging |
Het |
| Tnpo2 |
G |
A |
8: 85,776,748 (GRCm39) |
R485H |
probably damaging |
Het |
| Tnxb |
A |
G |
17: 34,937,492 (GRCm39) |
D2947G |
probably damaging |
Het |
| Traf4 |
A |
G |
11: 78,051,617 (GRCm39) |
|
probably null |
Het |
| Trappc10 |
A |
T |
10: 78,045,218 (GRCm39) |
M490K |
possibly damaging |
Het |
| Trav12-1 |
A |
G |
14: 53,775,993 (GRCm39) |
T49A |
probably benign |
Het |
| Ubap1l |
AGAGGAGGAGGAGGAGGA |
AGAGGAGGAGGAGGA |
9: 65,279,032 (GRCm39) |
|
probably benign |
Het |
| Unc79 |
G |
T |
12: 103,137,837 (GRCm39) |
V2485L |
probably benign |
Het |
| Ush2a |
T |
C |
1: 188,132,360 (GRCm39) |
S861P |
probably damaging |
Het |
| Vcam1 |
A |
G |
3: 115,910,877 (GRCm39) |
V507A |
possibly damaging |
Het |
| Vmn1r218 |
A |
G |
13: 23,320,895 (GRCm39) |
M81V |
probably benign |
Het |
| Zfp652 |
G |
T |
11: 95,643,830 (GRCm39) |
V343L |
probably damaging |
Het |
|
| Other mutations in Gcc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00088:Gcc2
|
APN |
10 |
58,128,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Gcc2
|
APN |
10 |
58,094,070 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00935:Gcc2
|
APN |
10 |
58,114,601 (GRCm39) |
splice site |
probably benign |
|
|
IGL01551:Gcc2
|
APN |
10 |
58,134,691 (GRCm39) |
splice site |
probably benign |
|
|
IGL01642:Gcc2
|
APN |
10 |
58,116,434 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02041:Gcc2
|
APN |
10 |
58,105,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02215:Gcc2
|
APN |
10 |
58,107,458 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL02448:Gcc2
|
APN |
10 |
58,128,393 (GRCm39) |
nonsense |
probably null |
|
|
IGL02698:Gcc2
|
APN |
10 |
58,107,112 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL02888:Gcc2
|
APN |
10 |
58,130,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02936:Gcc2
|
APN |
10 |
58,131,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03223:Gcc2
|
APN |
10 |
58,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03249:Gcc2
|
APN |
10 |
58,106,814 (GRCm39) |
nonsense |
probably null |
|
|
R0179:Gcc2
|
UTSW |
10 |
58,112,472 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0528:Gcc2
|
UTSW |
10 |
58,134,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1569:Gcc2
|
UTSW |
10 |
58,105,993 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1606:Gcc2
|
UTSW |
10 |
58,105,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1725:Gcc2
|
UTSW |
10 |
58,139,937 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1916:Gcc2
|
UTSW |
10 |
58,112,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Gcc2
|
UTSW |
10 |
58,121,965 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2058:Gcc2
|
UTSW |
10 |
58,121,779 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2114:Gcc2
|
UTSW |
10 |
58,105,362 (GRCm39) |
nonsense |
probably null |
|
|
R2280:Gcc2
|
UTSW |
10 |
58,105,502 (GRCm39) |
missense |
probably benign |
0.38 |
|
R2435:Gcc2
|
UTSW |
10 |
58,130,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2876:Gcc2
|
UTSW |
10 |
58,126,124 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4753:Gcc2
|
UTSW |
10 |
58,126,204 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4827:Gcc2
|
UTSW |
10 |
58,121,953 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4911:Gcc2
|
UTSW |
10 |
58,106,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5033:Gcc2
|
UTSW |
10 |
58,114,628 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5224:Gcc2
|
UTSW |
10 |
58,121,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5271:Gcc2
|
UTSW |
10 |
58,105,517 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5398:Gcc2
|
UTSW |
10 |
58,105,329 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5411:Gcc2
|
UTSW |
10 |
58,106,791 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5594:Gcc2
|
UTSW |
10 |
58,123,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5825:Gcc2
|
UTSW |
10 |
58,130,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5974:Gcc2
|
UTSW |
10 |
58,094,065 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5987:Gcc2
|
UTSW |
10 |
58,091,669 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R6195:Gcc2
|
UTSW |
10 |
58,106,806 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6198:Gcc2
|
UTSW |
10 |
58,128,412 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6233:Gcc2
|
UTSW |
10 |
58,106,806 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6331:Gcc2
|
UTSW |
10 |
58,107,287 (GRCm39) |
missense |
probably benign |
|
|
R6349:Gcc2
|
UTSW |
10 |
58,105,296 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6593:Gcc2
|
UTSW |
10 |
58,107,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6632:Gcc2
|
UTSW |
10 |
58,105,871 (GRCm39) |
splice site |
probably null |
|
|
R6647:Gcc2
|
UTSW |
10 |
58,123,103 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6774:Gcc2
|
UTSW |
10 |
58,117,261 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6808:Gcc2
|
UTSW |
10 |
58,094,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7072:Gcc2
|
UTSW |
10 |
58,106,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7220:Gcc2
|
UTSW |
10 |
58,116,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7352:Gcc2
|
UTSW |
10 |
58,116,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7439:Gcc2
|
UTSW |
10 |
58,092,723 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7441:Gcc2
|
UTSW |
10 |
58,092,723 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7543:Gcc2
|
UTSW |
10 |
58,107,086 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7843:Gcc2
|
UTSW |
10 |
58,103,843 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7850:Gcc2
|
UTSW |
10 |
58,114,703 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7980:Gcc2
|
UTSW |
10 |
58,114,574 (GRCm39) |
splice site |
probably null |
|
|
R8336:Gcc2
|
UTSW |
10 |
58,108,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8785:Gcc2
|
UTSW |
10 |
58,107,086 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8834:Gcc2
|
UTSW |
10 |
58,121,867 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9006:Gcc2
|
UTSW |
10 |
58,103,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Gcc2
|
UTSW |
10 |
58,106,411 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9240:Gcc2
|
UTSW |
10 |
58,106,398 (GRCm39) |
nonsense |
probably null |
|
|
R9287:Gcc2
|
UTSW |
10 |
58,105,217 (GRCm39) |
nonsense |
probably null |
|
|
R9370:Gcc2
|
UTSW |
10 |
58,131,940 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9433:Gcc2
|
UTSW |
10 |
58,106,592 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9653:Gcc2
|
UTSW |
10 |
58,110,822 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
X0018:Gcc2
|
UTSW |
10 |
58,114,636 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGAGGCAAGTGAGAACATTCC -3'
(R):5'- TTCCACAGCACAGCAAAGTTG -3'
Sequencing Primer
(F):5'- TCCAGAGAAATACCAATGTGAATCG -3'
(R):5'- AAGTTGCCTATTTAAATCTTCTCGC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation