Incidental Mutation 'R4967:Tacc2'
| ID |
384119 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tacc2
|
| Ensembl Gene |
ENSMUSG00000030852 |
| Gene Name |
transforming, acidic coiled-coil containing protein 2 |
| Synonyms |
|
| MMRRC Submission |
042563-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4967 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
130179168-130366515 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 130225678 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 807
(N807D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000149733
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000059145]
[ENSMUST00000084513]
[ENSMUST00000124096]
[ENSMUST00000207789]
[ENSMUST00000207918]
[ENSMUST00000208722]
[ENSMUST00000215492]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000059145
|
| SMART Domains |
Protein: ENSMUSP00000061242
Gene: ENSMUSG00000030852
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
87 |
102 |
N/A |
INTRINSIC |
|
low complexity region
|
147 |
173 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
181 |
291 |
2.03e-5 |
PROSPERO |
|
low complexity region
|
345 |
356 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
483 |
566 |
2.03e-5 |
PROSPERO |
|
low complexity region
|
571 |
586 |
N/A |
INTRINSIC |
|
low complexity region
|
603 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
648 |
662 |
N/A |
INTRINSIC |
|
coiled coil region
|
873 |
900 |
N/A |
INTRINSIC |
|
Pfam:TACC
|
939 |
1145 |
4e-85 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000084513
AA Change: N788D
PolyPhen 2
Score 0.045 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000081561
Gene: ENSMUSG00000030852
AA Change: N788D
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
19 |
346 |
3.83e-6 |
PROSPERO |
|
low complexity region
|
398 |
410 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
431 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
778 |
1068 |
3.83e-6 |
PROSPERO |
|
low complexity region
|
1397 |
1415 |
N/A |
INTRINSIC |
|
low complexity region
|
1723 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1794 |
1809 |
N/A |
INTRINSIC |
|
low complexity region
|
1854 |
1880 |
N/A |
INTRINSIC |
|
low complexity region
|
2052 |
2063 |
N/A |
INTRINSIC |
|
low complexity region
|
2278 |
2293 |
N/A |
INTRINSIC |
|
low complexity region
|
2310 |
2321 |
N/A |
INTRINSIC |
|
low complexity region
|
2355 |
2369 |
N/A |
INTRINSIC |
|
coiled coil region
|
2606 |
2633 |
N/A |
INTRINSIC |
|
Pfam:TACC
|
2673 |
2873 |
6.1e-87 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124096
|
| SMART Domains |
Protein: ENSMUSP00000130971
Gene: ENSMUSG00000030849
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
1 |
118 |
4.8e-19 |
PFAM |
|
Pfam:Pkinase_Tyr
|
1 |
118 |
1.7e-50 |
PFAM |
|
low complexity region
|
146 |
160 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207789
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000207918
AA Change: N788D
PolyPhen 2
Score 0.944 (Sensitivity: 0.80; Specificity: 0.95)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000207999
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208722
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000215492
AA Change: N807D
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
100% (102/102) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the transforming, acidic coiled-coil (TACC) family of proteins. Members of this family are centrosomal proteins that interact with microtubules and tubulin. TACC proteins are thought to be involved in centrosome/mitotic spindle dynamics and gene regulation. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null mice are healthy and fertile and do not display any increase in tumorigenesis. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930447C04Rik |
A |
T |
12: 72,956,502 (GRCm39) |
Y199* |
probably null |
Het |
| Adhfe1 |
A |
T |
1: 9,637,029 (GRCm39) |
I394F |
probably benign |
Het |
| Arhgap26 |
G |
T |
18: 39,379,893 (GRCm39) |
R485L |
probably damaging |
Het |
| Atat1 |
T |
A |
17: 36,212,467 (GRCm39) |
N231I |
probably damaging |
Het |
| B4galnt2 |
T |
C |
11: 95,760,100 (GRCm39) |
N309S |
probably benign |
Het |
| Bank1 |
A |
T |
3: 135,772,134 (GRCm39) |
F499I |
probably damaging |
Het |
| Bcl9l |
A |
G |
9: 44,416,365 (GRCm39) |
D146G |
possibly damaging |
Het |
| Bglap3 |
A |
T |
3: 88,283,671 (GRCm39) |
|
probably benign |
Het |
| Bscl2 |
C |
A |
19: 8,825,344 (GRCm39) |
T376K |
probably benign |
Het |
| Cercam |
A |
T |
2: 29,761,033 (GRCm39) |
|
probably null |
Het |
| Clec4f |
C |
T |
6: 83,633,012 (GRCm39) |
M1I |
probably null |
Het |
| Clec4n |
A |
T |
6: 123,209,066 (GRCm39) |
I14F |
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,227,093 (GRCm39) |
E2665G |
probably damaging |
Het |
| Cog4 |
T |
A |
8: 111,578,915 (GRCm39) |
|
probably null |
Het |
| Cubn |
A |
G |
2: 13,352,856 (GRCm39) |
F1961L |
probably benign |
Het |
| Cyp4a29 |
A |
T |
4: 115,104,196 (GRCm39) |
H88L |
probably benign |
Het |
| Dhdh |
A |
G |
7: 45,128,530 (GRCm39) |
L216P |
probably damaging |
Het |
| Dpp6 |
T |
C |
5: 27,871,509 (GRCm39) |
F544S |
probably damaging |
Het |
| Dthd1 |
C |
T |
5: 63,045,549 (GRCm39) |
T771I |
probably benign |
Het |
| Emc10 |
A |
G |
7: 44,142,612 (GRCm39) |
|
probably null |
Het |
| Fgg |
A |
T |
3: 82,920,072 (GRCm39) |
T284S |
probably benign |
Het |
| Gask1a |
C |
T |
9: 121,794,784 (GRCm39) |
R313W |
probably damaging |
Het |
| Gm3002 |
T |
A |
14: 3,824,737 (GRCm38) |
N24K |
probably damaging |
Het |
| Gm8674 |
G |
A |
13: 50,056,034 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr63 |
G |
A |
4: 25,008,368 (GRCm39) |
W364* |
probably null |
Het |
| Hcn4 |
C |
G |
9: 58,767,111 (GRCm39) |
P891A |
unknown |
Het |
| Hcrtr1 |
A |
T |
4: 130,024,792 (GRCm39) |
F365I |
possibly damaging |
Het |
| Hmcn2 |
A |
G |
2: 31,244,176 (GRCm39) |
|
probably null |
Het |
| Hoxc5 |
T |
A |
15: 102,923,786 (GRCm39) |
L194H |
probably damaging |
Het |
| Ifna11 |
A |
G |
4: 88,738,287 (GRCm39) |
N31S |
probably null |
Het |
| Ikbke |
GCC |
G |
1: 131,203,004 (GRCm39) |
|
probably null |
Het |
| Iqgap2 |
A |
T |
13: 95,766,514 (GRCm39) |
D1496E |
probably benign |
Het |
| Kif28 |
G |
T |
1: 179,536,007 (GRCm39) |
Q556K |
probably damaging |
Het |
| Klhl42 |
C |
T |
6: 147,009,502 (GRCm39) |
T447I |
possibly damaging |
Het |
| Lrp1b |
A |
C |
2: 41,678,986 (GRCm39) |
D35E |
probably damaging |
Het |
| Lsm14b |
A |
G |
2: 179,675,692 (GRCm39) |
|
probably benign |
Het |
| Map3k1 |
T |
C |
13: 111,909,272 (GRCm39) |
E226G |
probably damaging |
Het |
| Map3k14 |
T |
A |
11: 103,130,357 (GRCm39) |
N187Y |
probably benign |
Het |
| Mcm6 |
A |
T |
1: 128,263,586 (GRCm39) |
V645E |
probably damaging |
Het |
| Mdh1b |
G |
T |
1: 63,759,022 (GRCm39) |
P190Q |
probably damaging |
Het |
| Meiob |
T |
G |
17: 25,037,353 (GRCm39) |
L77R |
probably damaging |
Het |
| Mrgpra3 |
A |
T |
7: 47,239,267 (GRCm39) |
F220I |
probably benign |
Het |
| Mrtfa |
C |
A |
15: 80,929,476 (GRCm39) |
|
probably benign |
Het |
| Mtor |
T |
A |
4: 148,575,817 (GRCm39) |
S1324T |
possibly damaging |
Het |
| Myot |
T |
A |
18: 44,487,995 (GRCm39) |
D437E |
possibly damaging |
Het |
| Ncoa6 |
G |
T |
2: 155,263,252 (GRCm39) |
T394K |
possibly damaging |
Het |
| Nf1 |
T |
A |
11: 79,456,379 (GRCm39) |
|
probably null |
Het |
| Nup210 |
T |
A |
6: 91,013,451 (GRCm39) |
T1190S |
possibly damaging |
Het |
| Odf1 |
T |
A |
15: 38,226,652 (GRCm39) |
I184N |
probably damaging |
Het |
| Or10d1 |
C |
T |
9: 39,484,054 (GRCm39) |
C167Y |
probably damaging |
Het |
| Or13d1 |
T |
C |
4: 52,970,960 (GRCm39) |
V113A |
possibly damaging |
Het |
| Or1n1b |
A |
G |
2: 36,780,719 (GRCm39) |
I47T |
probably damaging |
Het |
| Or5k15 |
G |
T |
16: 58,709,957 (GRCm39) |
Q209K |
possibly damaging |
Het |
| Padi1 |
A |
G |
4: 140,572,901 (GRCm39) |
V21A |
probably benign |
Het |
| Pdzrn3 |
C |
T |
6: 101,128,551 (GRCm39) |
R705H |
probably damaging |
Het |
| Pik3cb |
T |
C |
9: 98,987,685 (GRCm39) |
I18V |
probably benign |
Het |
| Pmpca |
T |
C |
2: 26,280,320 (GRCm39) |
S117P |
probably damaging |
Het |
| Poteg |
T |
A |
8: 27,985,009 (GRCm39) |
|
probably benign |
Het |
| Pramel32 |
T |
C |
4: 88,547,432 (GRCm39) |
T80A |
probably damaging |
Het |
| Rab30 |
G |
A |
7: 92,478,771 (GRCm39) |
R72H |
probably damaging |
Het |
| Ramp2 |
T |
A |
11: 101,138,383 (GRCm39) |
|
probably null |
Het |
| Rbks |
G |
A |
5: 31,781,876 (GRCm39) |
T308I |
probably damaging |
Het |
| Rnf112 |
A |
G |
11: 61,343,752 (GRCm39) |
|
probably benign |
Het |
| Rnf38 |
G |
A |
4: 44,152,460 (GRCm39) |
P3S |
probably damaging |
Het |
| Sec16a |
A |
G |
2: 26,302,883 (GRCm39) |
S2344P |
probably benign |
Het |
| Slc16a8 |
C |
T |
15: 79,137,084 (GRCm39) |
V109M |
possibly damaging |
Het |
| Slc28a1 |
A |
T |
7: 80,791,757 (GRCm39) |
T308S |
possibly damaging |
Het |
| Slc39a3 |
T |
C |
10: 80,867,453 (GRCm39) |
T98A |
possibly damaging |
Het |
| Smarcc2 |
T |
C |
10: 128,319,049 (GRCm39) |
F731L |
probably damaging |
Het |
| Smc4 |
A |
G |
3: 68,925,572 (GRCm39) |
|
probably benign |
Het |
| Sparcl1 |
T |
G |
5: 104,240,776 (GRCm39) |
D216A |
probably damaging |
Het |
| Speg |
G |
A |
1: 75,364,513 (GRCm39) |
R192H |
probably damaging |
Het |
| Sspo |
T |
C |
6: 48,441,539 (GRCm39) |
L1892P |
probably damaging |
Het |
| Styxl2 |
A |
T |
1: 165,954,675 (GRCm39) |
V25E |
probably damaging |
Het |
| Teddm1a |
A |
T |
1: 153,767,979 (GRCm39) |
K148* |
probably null |
Het |
| Tex15 |
T |
A |
8: 34,064,498 (GRCm39) |
D1309E |
probably benign |
Het |
| Thbs1 |
A |
T |
2: 117,945,259 (GRCm39) |
E277D |
probably benign |
Het |
| Ticrr |
G |
A |
7: 79,310,158 (GRCm39) |
R24Q |
probably damaging |
Het |
| Tigd4 |
A |
G |
3: 84,502,460 (GRCm39) |
E459G |
probably benign |
Het |
| Tln2 |
C |
A |
9: 67,262,407 (GRCm39) |
A615S |
probably damaging |
Het |
| Tmprss5 |
T |
C |
9: 49,026,817 (GRCm39) |
V410A |
probably damaging |
Het |
| Tnrc6a |
G |
T |
7: 122,789,095 (GRCm39) |
W1638L |
probably damaging |
Het |
| Tpr |
A |
G |
1: 150,285,810 (GRCm39) |
D424G |
probably damaging |
Het |
| Trim34a |
A |
T |
7: 103,910,271 (GRCm39) |
K358* |
probably null |
Het |
| Tssk5 |
T |
A |
15: 76,258,856 (GRCm39) |
D10V |
possibly damaging |
Het |
| Usp35 |
A |
C |
7: 96,962,782 (GRCm39) |
L470R |
probably damaging |
Het |
| Usp42 |
T |
C |
5: 143,701,119 (GRCm39) |
D968G |
possibly damaging |
Het |
| Utrn |
A |
G |
10: 12,331,164 (GRCm39) |
V2924A |
probably damaging |
Het |
| Wdtc1 |
C |
A |
4: 133,021,654 (GRCm39) |
A627S |
probably damaging |
Het |
| Xrra1 |
A |
G |
7: 99,555,730 (GRCm39) |
T366A |
probably damaging |
Het |
| Zfp712 |
T |
A |
13: 67,188,773 (GRCm39) |
K585* |
probably null |
Het |
| Zfp97 |
T |
A |
17: 17,365,393 (GRCm39) |
N297K |
probably damaging |
Het |
| Zfp97 |
G |
T |
17: 17,364,938 (GRCm39) |
E146* |
probably null |
Het |
|
| Other mutations in Tacc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00836:Tacc2
|
APN |
7 |
130,360,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01396:Tacc2
|
APN |
7 |
130,360,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01621:Tacc2
|
APN |
7 |
130,331,498 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02000:Tacc2
|
APN |
7 |
130,330,898 (GRCm39) |
splice site |
probably null |
|
|
IGL02075:Tacc2
|
APN |
7 |
130,330,582 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02201:Tacc2
|
APN |
7 |
130,227,942 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02205:Tacc2
|
APN |
7 |
130,228,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02399:Tacc2
|
APN |
7 |
130,225,129 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02456:Tacc2
|
APN |
7 |
130,227,991 (GRCm39) |
missense |
probably benign |
0.35 |
|
IGL02559:Tacc2
|
APN |
7 |
130,360,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02734:Tacc2
|
APN |
7 |
130,227,829 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02800:Tacc2
|
APN |
7 |
130,225,809 (GRCm39) |
missense |
probably benign |
0.40 |
|
IGL02938:Tacc2
|
APN |
7 |
130,330,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03031:Tacc2
|
APN |
7 |
130,225,585 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03278:Tacc2
|
APN |
7 |
130,335,298 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03283:Tacc2
|
APN |
7 |
130,343,996 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL03371:Tacc2
|
APN |
7 |
130,227,791 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
aces
|
UTSW |
7 |
130,335,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Jacks
|
UTSW |
7 |
130,227,494 (GRCm39) |
missense |
probably damaging |
0.98 |
|
kings
|
UTSW |
7 |
130,225,213 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0002:Tacc2
|
UTSW |
7 |
130,223,515 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0119:Tacc2
|
UTSW |
7 |
130,223,605 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0244:Tacc2
|
UTSW |
7 |
130,353,555 (GRCm39) |
splice site |
probably benign |
|
|
R0619:Tacc2
|
UTSW |
7 |
130,318,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0624:Tacc2
|
UTSW |
7 |
130,179,239 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0632:Tacc2
|
UTSW |
7 |
130,227,325 (GRCm39) |
nonsense |
probably null |
|
|
R1015:Tacc2
|
UTSW |
7 |
130,225,795 (GRCm39) |
missense |
probably benign |
|
|
R1081:Tacc2
|
UTSW |
7 |
130,330,304 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1086:Tacc2
|
UTSW |
7 |
130,228,227 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1351:Tacc2
|
UTSW |
7 |
130,264,733 (GRCm39) |
intron |
probably benign |
|
|
R1538:Tacc2
|
UTSW |
7 |
130,227,149 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1743:Tacc2
|
UTSW |
7 |
130,228,328 (GRCm39) |
nonsense |
probably null |
|
|
R1771:Tacc2
|
UTSW |
7 |
130,343,970 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1876:Tacc2
|
UTSW |
7 |
130,225,475 (GRCm39) |
missense |
probably benign |
0.38 |
|
R1893:Tacc2
|
UTSW |
7 |
130,227,055 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1899:Tacc2
|
UTSW |
7 |
130,225,932 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R2005:Tacc2
|
UTSW |
7 |
130,333,280 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Tacc2
|
UTSW |
7 |
130,223,587 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2338:Tacc2
|
UTSW |
7 |
130,335,299 (GRCm39) |
splice site |
probably null |
|
|
R2407:Tacc2
|
UTSW |
7 |
130,223,770 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R3051:Tacc2
|
UTSW |
7 |
130,227,226 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3052:Tacc2
|
UTSW |
7 |
130,227,226 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3053:Tacc2
|
UTSW |
7 |
130,227,226 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R3116:Tacc2
|
UTSW |
7 |
130,360,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3412:Tacc2
|
UTSW |
7 |
130,336,724 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3683:Tacc2
|
UTSW |
7 |
130,226,800 (GRCm39) |
missense |
probably benign |
0.40 |
|
R3685:Tacc2
|
UTSW |
7 |
130,226,800 (GRCm39) |
missense |
probably benign |
0.40 |
|
R3872:Tacc2
|
UTSW |
7 |
130,224,152 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4063:Tacc2
|
UTSW |
7 |
130,330,852 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4410:Tacc2
|
UTSW |
7 |
130,343,941 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4434:Tacc2
|
UTSW |
7 |
130,225,271 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4438:Tacc2
|
UTSW |
7 |
130,225,271 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4618:Tacc2
|
UTSW |
7 |
130,227,946 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4674:Tacc2
|
UTSW |
7 |
130,226,591 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4742:Tacc2
|
UTSW |
7 |
130,227,697 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4934:Tacc2
|
UTSW |
7 |
130,330,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4947:Tacc2
|
UTSW |
7 |
130,227,629 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4964:Tacc2
|
UTSW |
7 |
130,330,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4966:Tacc2
|
UTSW |
7 |
130,330,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5052:Tacc2
|
UTSW |
7 |
130,336,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5276:Tacc2
|
UTSW |
7 |
130,331,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5330:Tacc2
|
UTSW |
7 |
130,335,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5331:Tacc2
|
UTSW |
7 |
130,335,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Tacc2
|
UTSW |
7 |
130,224,990 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5556:Tacc2
|
UTSW |
7 |
130,276,336 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5645:Tacc2
|
UTSW |
7 |
130,225,781 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5886:Tacc2
|
UTSW |
7 |
130,330,850 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5996:Tacc2
|
UTSW |
7 |
130,225,213 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6074:Tacc2
|
UTSW |
7 |
130,227,165 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6127:Tacc2
|
UTSW |
7 |
130,227,845 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6156:Tacc2
|
UTSW |
7 |
130,227,494 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6298:Tacc2
|
UTSW |
7 |
130,228,255 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6444:Tacc2
|
UTSW |
7 |
130,225,142 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6533:Tacc2
|
UTSW |
7 |
130,224,567 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6724:Tacc2
|
UTSW |
7 |
130,330,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7111:Tacc2
|
UTSW |
7 |
130,330,618 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7150:Tacc2
|
UTSW |
7 |
130,330,807 (GRCm39) |
missense |
probably benign |
|
|
R7290:Tacc2
|
UTSW |
7 |
130,331,103 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7404:Tacc2
|
UTSW |
7 |
130,225,066 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7460:Tacc2
|
UTSW |
7 |
130,226,363 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7651:Tacc2
|
UTSW |
7 |
130,224,884 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7666:Tacc2
|
UTSW |
7 |
130,318,544 (GRCm39) |
start gained |
probably benign |
|
|
R7695:Tacc2
|
UTSW |
7 |
130,330,633 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7766:Tacc2
|
UTSW |
7 |
130,345,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7793:Tacc2
|
UTSW |
7 |
130,224,843 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7861:Tacc2
|
UTSW |
7 |
130,227,161 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8204:Tacc2
|
UTSW |
7 |
130,226,159 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8244:Tacc2
|
UTSW |
7 |
130,330,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8245:Tacc2
|
UTSW |
7 |
130,331,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8283:Tacc2
|
UTSW |
7 |
130,227,034 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8348:Tacc2
|
UTSW |
7 |
130,225,019 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8369:Tacc2
|
UTSW |
7 |
130,223,888 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8381:Tacc2
|
UTSW |
7 |
130,225,972 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8804:Tacc2
|
UTSW |
7 |
130,294,693 (GRCm39) |
missense |
probably benign |
|
|
R8809:Tacc2
|
UTSW |
7 |
130,276,421 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8835:Tacc2
|
UTSW |
7 |
130,228,258 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8880:Tacc2
|
UTSW |
7 |
130,318,564 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8918:Tacc2
|
UTSW |
7 |
130,227,823 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8936:Tacc2
|
UTSW |
7 |
130,228,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8953:Tacc2
|
UTSW |
7 |
130,227,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9026:Tacc2
|
UTSW |
7 |
130,225,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9193:Tacc2
|
UTSW |
7 |
130,228,304 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9221:Tacc2
|
UTSW |
7 |
130,226,209 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9221:Tacc2
|
UTSW |
7 |
130,226,058 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9222:Tacc2
|
UTSW |
7 |
130,227,985 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9264:Tacc2
|
UTSW |
7 |
130,228,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9312:Tacc2
|
UTSW |
7 |
130,223,978 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9380:Tacc2
|
UTSW |
7 |
130,226,771 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9515:Tacc2
|
UTSW |
7 |
130,366,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9705:Tacc2
|
UTSW |
7 |
130,361,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0010:Tacc2
|
UTSW |
7 |
130,336,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tacc2
|
UTSW |
7 |
130,346,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tacc2
|
UTSW |
7 |
130,226,000 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
Z1176:Tacc2
|
UTSW |
7 |
130,225,100 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Tacc2
|
UTSW |
7 |
130,336,679 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
Z1177:Tacc2
|
UTSW |
7 |
130,227,504 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Tacc2
|
UTSW |
7 |
130,226,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAAGAGCCACTCACCCTTTC -3'
(R):5'- AAGGCTTCCTTTCCTCAGGTAC -3'
Sequencing Primer
(F):5'- AAGGCTTGCTGATGTCCC -3'
(R):5'- TCCTCAGGTACCAGGATTGAG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation