Incidental Mutation 'R2117:Gcn1'
| ID |
231054 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Gcn1
|
| Ensembl Gene |
ENSMUSG00000041638 |
| Gene Name |
GCN1 activator of EIF2AK4 |
| Synonyms |
Gcn1l1, G431004K08Rik, GCN1L |
| MMRRC Submission |
040121-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.948)
|
| Stock # |
R2117 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
115703313-115760713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 115736884 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 1276
(M1276L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000069432
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064454]
|
| AlphaFold |
E9PVA8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064454
AA Change: M1276L
PolyPhen 2
Score 0.351 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000069432
Gene: ENSMUSG00000041638
AA Change: M1276L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
64 |
84 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
117 |
N/A |
INTRINSIC |
|
low complexity region
|
142 |
154 |
N/A |
INTRINSIC |
|
Pfam:DUF3554
|
357 |
705 |
2e-61 |
PFAM |
|
coiled coil region
|
806 |
866 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1028 |
1068 |
6e-11 |
BLAST |
|
coiled coil region
|
1180 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1466 |
N/A |
INTRINSIC |
|
low complexity region
|
1501 |
1510 |
N/A |
INTRINSIC |
|
ARM
|
1527 |
1567 |
3.69e1 |
SMART |
|
Blast:ARM
|
1602 |
1644 |
1e-5 |
BLAST |
|
Blast:EZ_HEAT
|
1671 |
1704 |
1e-7 |
BLAST |
|
low complexity region
|
1926 |
1934 |
N/A |
INTRINSIC |
|
low complexity region
|
1956 |
1972 |
N/A |
INTRINSIC |
|
ARM
|
2034 |
2070 |
9.27e1 |
SMART |
|
low complexity region
|
2326 |
2334 |
N/A |
INTRINSIC |
|
ARM
|
2416 |
2455 |
2.16e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151030
AA Change: H877L
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgrv1 |
A |
T |
13: 81,640,656 (GRCm39) |
C3357S |
probably benign |
Het |
| Ago1 |
T |
A |
4: 126,357,650 (GRCm39) |
|
probably null |
Het |
| Akap10 |
A |
T |
11: 61,781,129 (GRCm39) |
D562E |
possibly damaging |
Het |
| Akr1b7 |
G |
A |
6: 34,395,929 (GRCm39) |
A144T |
possibly damaging |
Het |
| Ankle1 |
A |
G |
8: 71,860,562 (GRCm39) |
T340A |
probably benign |
Het |
| Arf5 |
C |
T |
6: 28,424,783 (GRCm39) |
Q71* |
probably null |
Het |
| Arl15 |
C |
T |
13: 114,104,196 (GRCm39) |
S111F |
probably damaging |
Het |
| Asph |
G |
A |
4: 9,517,671 (GRCm39) |
Q468* |
probably null |
Het |
| Bcam |
G |
T |
7: 19,492,352 (GRCm39) |
A581E |
possibly damaging |
Het |
| Blvra |
G |
T |
2: 126,927,989 (GRCm39) |
E80* |
probably null |
Het |
| Ccr6 |
T |
C |
17: 8,474,914 (GRCm39) |
F40L |
possibly damaging |
Het |
| Cfap161 |
A |
T |
7: 83,425,184 (GRCm39) |
N302K |
possibly damaging |
Het |
| Ckmt2 |
T |
A |
13: 92,003,964 (GRCm39) |
I345F |
probably benign |
Het |
| Cpsf6 |
A |
G |
10: 117,202,025 (GRCm39) |
|
probably benign |
Het |
| Ctnna1 |
A |
G |
18: 35,285,678 (GRCm39) |
N8S |
possibly damaging |
Het |
| Cyp2d11 |
A |
G |
15: 82,275,954 (GRCm39) |
L209P |
probably damaging |
Het |
| Dab2 |
T |
C |
15: 6,465,096 (GRCm39) |
V628A |
probably damaging |
Het |
| Dcstamp |
C |
T |
15: 39,618,571 (GRCm39) |
Q327* |
probably null |
Het |
| Defb38 |
A |
T |
8: 19,073,483 (GRCm39) |
Y63* |
probably null |
Het |
| Dlg5 |
A |
T |
14: 24,227,826 (GRCm39) |
L365* |
probably null |
Het |
| Dnai7 |
C |
T |
6: 145,150,967 (GRCm39) |
|
probably null |
Het |
| Dnmt3l |
C |
A |
10: 77,899,130 (GRCm39) |
L110I |
probably damaging |
Het |
| Exoc3l2 |
G |
T |
7: 19,228,907 (GRCm39) |
L108F |
possibly damaging |
Het |
| Exoc4 |
T |
A |
6: 33,324,760 (GRCm39) |
N351K |
possibly damaging |
Het |
| Fam83h |
C |
A |
15: 75,876,582 (GRCm39) |
E252* |
probably null |
Het |
| Fancm |
A |
G |
12: 65,123,948 (GRCm39) |
D202G |
probably damaging |
Het |
| Fat1 |
T |
A |
8: 45,490,500 (GRCm39) |
V3804E |
probably benign |
Het |
| Fbxw28 |
T |
C |
9: 109,159,985 (GRCm39) |
T190A |
probably benign |
Het |
| Fer1l4 |
T |
C |
2: 155,881,038 (GRCm39) |
T843A |
probably benign |
Het |
| Fnip1 |
A |
T |
11: 54,391,450 (GRCm39) |
H461L |
probably damaging |
Het |
| Gemin4 |
A |
G |
11: 76,101,827 (GRCm39) |
V978A |
possibly damaging |
Het |
| Gm7247 |
A |
T |
14: 51,602,792 (GRCm39) |
I43F |
probably damaging |
Het |
| Gm9978 |
C |
T |
10: 78,322,731 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr4 |
T |
C |
7: 18,957,070 (GRCm39) |
S331P |
probably damaging |
Het |
| Hspa1a |
T |
A |
17: 35,189,455 (GRCm39) |
N483Y |
probably damaging |
Het |
| Ift74 |
A |
G |
4: 94,515,496 (GRCm39) |
T138A |
probably benign |
Het |
| Ints14 |
T |
G |
9: 64,887,077 (GRCm39) |
L336R |
probably damaging |
Het |
| Irak1 |
G |
T |
X: 73,066,218 (GRCm39) |
P197Q |
possibly damaging |
Het |
| Kif4 |
A |
G |
X: 99,709,323 (GRCm39) |
S315G |
probably benign |
Het |
| L3mbtl1 |
T |
A |
2: 162,801,990 (GRCm39) |
|
probably null |
Het |
| Lamb3 |
A |
G |
1: 193,016,489 (GRCm39) |
R657G |
probably benign |
Het |
| Ldc1 |
C |
A |
4: 130,109,156 (GRCm39) |
V295L |
possibly damaging |
Het |
| Lrp2 |
A |
C |
2: 69,313,729 (GRCm39) |
V2334G |
probably benign |
Het |
| Lrwd1 |
T |
A |
5: 136,159,332 (GRCm39) |
Y431F |
probably damaging |
Het |
| Map3k21 |
A |
T |
8: 126,650,781 (GRCm39) |
H261L |
probably benign |
Het |
| Meis1 |
G |
T |
11: 18,831,679 (GRCm39) |
P453Q |
probably damaging |
Het |
| Mettl16 |
G |
T |
11: 74,693,755 (GRCm39) |
M255I |
probably benign |
Het |
| Mllt10 |
A |
G |
2: 18,167,380 (GRCm39) |
N435S |
probably benign |
Het |
| Mta2 |
T |
C |
19: 8,920,880 (GRCm39) |
I27T |
probably damaging |
Het |
| Nav2 |
A |
G |
7: 49,114,328 (GRCm39) |
I771V |
probably benign |
Het |
| Nisch |
A |
T |
14: 30,899,242 (GRCm39) |
|
probably benign |
Het |
| Npc1 |
G |
A |
18: 12,329,613 (GRCm39) |
P990L |
probably damaging |
Het |
| Nrxn1 |
A |
T |
17: 91,011,705 (GRCm39) |
I308K |
probably damaging |
Het |
| Or13l2 |
C |
A |
3: 97,317,765 (GRCm39) |
C244F |
probably damaging |
Het |
| Or1ad6 |
A |
T |
11: 50,860,147 (GRCm39) |
I101F |
probably damaging |
Het |
| Or5h17 |
T |
C |
16: 58,820,783 (GRCm39) |
L245P |
possibly damaging |
Het |
| Otogl |
T |
C |
10: 107,694,779 (GRCm39) |
D823G |
probably benign |
Het |
| P2rx7 |
A |
G |
5: 122,819,329 (GRCm39) |
T584A |
probably benign |
Het |
| Pals1 |
T |
C |
12: 78,856,696 (GRCm39) |
F180L |
possibly damaging |
Het |
| Pank1 |
T |
A |
19: 34,818,486 (GRCm39) |
I18F |
probably damaging |
Het |
| Pgap3 |
A |
G |
11: 98,281,933 (GRCm39) |
L126P |
probably damaging |
Het |
| Pgap6 |
C |
T |
17: 26,336,858 (GRCm39) |
L259F |
possibly damaging |
Het |
| Phka1 |
C |
T |
X: 101,653,807 (GRCm39) |
R290H |
probably damaging |
Het |
| Pkd2 |
G |
A |
5: 104,631,042 (GRCm39) |
E489K |
probably damaging |
Het |
| Prdm16 |
T |
A |
4: 154,432,382 (GRCm39) |
S296C |
probably null |
Het |
| Prex2 |
T |
A |
1: 11,256,937 (GRCm39) |
N1216K |
probably damaging |
Het |
| Prmt7 |
A |
G |
8: 106,953,930 (GRCm39) |
T124A |
probably damaging |
Het |
| Ptpra |
G |
T |
2: 130,381,655 (GRCm39) |
R372L |
probably damaging |
Het |
| Ptpro |
T |
A |
6: 137,420,592 (GRCm39) |
V1007D |
probably damaging |
Het |
| Rap2b |
G |
T |
3: 61,272,512 (GRCm39) |
G12V |
probably damaging |
Het |
| Rapgef5 |
T |
A |
12: 117,677,799 (GRCm39) |
|
probably null |
Het |
| Rassf4 |
A |
G |
6: 116,622,088 (GRCm39) |
F168S |
possibly damaging |
Het |
| Rtf1 |
T |
A |
2: 119,535,999 (GRCm39) |
H184Q |
probably benign |
Het |
| Sacs |
A |
G |
14: 61,451,220 (GRCm39) |
K4422R |
probably benign |
Het |
| Sec11c |
A |
T |
18: 65,933,720 (GRCm39) |
T9S |
probably benign |
Het |
| Sema3d |
C |
T |
5: 12,613,240 (GRCm39) |
T439I |
probably benign |
Het |
| Sephs1 |
A |
G |
2: 4,904,351 (GRCm39) |
N243S |
probably benign |
Het |
| Setd2 |
TTGGGA |
T |
9: 110,433,212 (GRCm39) |
|
probably null |
Het |
| Setx |
A |
G |
2: 29,020,313 (GRCm39) |
D100G |
probably benign |
Het |
| Slc22a7 |
C |
A |
17: 46,744,898 (GRCm39) |
V383L |
possibly damaging |
Het |
| Slc25a40 |
T |
C |
5: 8,480,417 (GRCm39) |
C56R |
probably damaging |
Het |
| Stk38l |
T |
A |
6: 146,670,344 (GRCm39) |
L229I |
probably damaging |
Het |
| Sult2a5 |
T |
C |
7: 13,359,359 (GRCm39) |
S112P |
probably damaging |
Het |
| Syt4 |
A |
G |
18: 31,573,520 (GRCm39) |
Y332H |
probably damaging |
Het |
| Tcof1 |
T |
C |
18: 60,965,857 (GRCm39) |
E415G |
possibly damaging |
Het |
| Tenm2 |
A |
G |
11: 35,915,681 (GRCm39) |
L1951P |
probably damaging |
Het |
| Tlr9 |
A |
G |
9: 106,102,536 (GRCm39) |
N609S |
probably damaging |
Het |
| Tmem120a |
A |
T |
5: 135,764,977 (GRCm39) |
S266T |
possibly damaging |
Het |
| Tmem132b |
A |
G |
5: 125,699,615 (GRCm39) |
E92G |
probably damaging |
Het |
| Tnfrsf18 |
T |
A |
4: 156,112,973 (GRCm39) |
V196E |
probably damaging |
Het |
| Trpc1 |
A |
T |
9: 95,599,637 (GRCm39) |
L474H |
probably damaging |
Het |
| Trpm6 |
T |
C |
19: 18,807,316 (GRCm39) |
V1020A |
probably damaging |
Het |
| Usp20 |
T |
A |
2: 30,906,317 (GRCm39) |
C562S |
probably damaging |
Het |
| Usp47 |
T |
A |
7: 111,666,443 (GRCm39) |
|
probably null |
Het |
| Vgll1 |
A |
C |
X: 56,137,790 (GRCm39) |
K53T |
probably damaging |
Het |
| Vmn1r26 |
T |
C |
6: 57,985,335 (GRCm39) |
N285D |
possibly damaging |
Het |
| Zfp445 |
T |
A |
9: 122,682,502 (GRCm39) |
K480* |
probably null |
Het |
| Zfp786 |
A |
G |
6: 47,803,931 (GRCm39) |
V37A |
probably damaging |
Het |
| Zfp821 |
A |
G |
8: 110,447,851 (GRCm39) |
E64G |
probably damaging |
Het |
| Zfp994 |
T |
A |
17: 22,419,962 (GRCm39) |
D329V |
probably damaging |
Het |
| Zkscan8 |
T |
C |
13: 21,704,488 (GRCm39) |
S484G |
probably damaging |
Het |
|
| Other mutations in Gcn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00869:Gcn1
|
APN |
5 |
115,726,202 (GRCm39) |
splice site |
probably benign |
|
|
IGL00974:Gcn1
|
APN |
5 |
115,751,852 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01566:Gcn1
|
APN |
5 |
115,749,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01843:Gcn1
|
APN |
5 |
115,757,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01885:Gcn1
|
APN |
5 |
115,714,174 (GRCm39) |
splice site |
probably null |
|
|
IGL02081:Gcn1
|
APN |
5 |
115,723,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02118:Gcn1
|
APN |
5 |
115,748,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02150:Gcn1
|
APN |
5 |
115,747,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02190:Gcn1
|
APN |
5 |
115,752,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02219:Gcn1
|
APN |
5 |
115,751,826 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL02507:Gcn1
|
APN |
5 |
115,723,940 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02644:Gcn1
|
APN |
5 |
115,713,250 (GRCm39) |
missense |
probably benign |
|
|
IGL02678:Gcn1
|
APN |
5 |
115,751,814 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02748:Gcn1
|
APN |
5 |
115,748,859 (GRCm39) |
splice site |
probably null |
|
|
IGL02755:Gcn1
|
APN |
5 |
115,742,065 (GRCm39) |
splice site |
probably null |
|
|
IGL02896:Gcn1
|
APN |
5 |
115,757,707 (GRCm39) |
splice site |
probably benign |
|
|
cusp
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
farthing
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
IGL03147:Gcn1
|
UTSW |
5 |
115,748,917 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0362:Gcn1
|
UTSW |
5 |
115,714,167 (GRCm39) |
splice site |
probably benign |
|
|
R0540:Gcn1
|
UTSW |
5 |
115,727,015 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0569:Gcn1
|
UTSW |
5 |
115,733,118 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0570:Gcn1
|
UTSW |
5 |
115,730,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Gcn1
|
UTSW |
5 |
115,733,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Gcn1
|
UTSW |
5 |
115,719,148 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0656:Gcn1
|
UTSW |
5 |
115,727,362 (GRCm39) |
missense |
probably benign |
0.27 |
|
R0801:Gcn1
|
UTSW |
5 |
115,729,065 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0890:Gcn1
|
UTSW |
5 |
115,717,852 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1400:Gcn1
|
UTSW |
5 |
115,752,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1485:Gcn1
|
UTSW |
5 |
115,712,676 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1574:Gcn1
|
UTSW |
5 |
115,753,611 (GRCm39) |
missense |
probably benign |
|
|
R1673:Gcn1
|
UTSW |
5 |
115,720,356 (GRCm39) |
missense |
probably benign |
|
|
R1894:Gcn1
|
UTSW |
5 |
115,727,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2114:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2116:Gcn1
|
UTSW |
5 |
115,736,884 (GRCm39) |
missense |
probably benign |
0.35 |
|
R2152:Gcn1
|
UTSW |
5 |
115,747,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
R2162:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2216:Gcn1
|
UTSW |
5 |
115,731,720 (GRCm39) |
missense |
probably benign |
|
|
R2218:Gcn1
|
UTSW |
5 |
115,757,720 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2278:Gcn1
|
UTSW |
5 |
115,749,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2280:Gcn1
|
UTSW |
5 |
115,750,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Gcn1
|
UTSW |
5 |
115,717,876 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3729:Gcn1
|
UTSW |
5 |
115,721,453 (GRCm39) |
splice site |
probably benign |
|
|
R3833:Gcn1
|
UTSW |
5 |
115,730,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R3932:Gcn1
|
UTSW |
5 |
115,725,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4067:Gcn1
|
UTSW |
5 |
115,737,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4152:Gcn1
|
UTSW |
5 |
115,751,413 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4179:Gcn1
|
UTSW |
5 |
115,726,109 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4292:Gcn1
|
UTSW |
5 |
115,714,207 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4350:Gcn1
|
UTSW |
5 |
115,741,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4493:Gcn1
|
UTSW |
5 |
115,732,203 (GRCm39) |
missense |
probably benign |
|
|
R4672:Gcn1
|
UTSW |
5 |
115,744,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4749:Gcn1
|
UTSW |
5 |
115,752,461 (GRCm39) |
missense |
probably benign |
|
|
R4753:Gcn1
|
UTSW |
5 |
115,754,537 (GRCm39) |
missense |
probably benign |
|
|
R4826:Gcn1
|
UTSW |
5 |
115,731,752 (GRCm39) |
missense |
probably benign |
|
|
R4873:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4875:Gcn1
|
UTSW |
5 |
115,714,229 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4932:Gcn1
|
UTSW |
5 |
115,730,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4992:Gcn1
|
UTSW |
5 |
115,737,225 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5049:Gcn1
|
UTSW |
5 |
115,744,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5211:Gcn1
|
UTSW |
5 |
115,757,371 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5226:Gcn1
|
UTSW |
5 |
115,726,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5338:Gcn1
|
UTSW |
5 |
115,721,462 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Gcn1
|
UTSW |
5 |
115,748,194 (GRCm39) |
synonymous |
silent |
|
|
R5932:Gcn1
|
UTSW |
5 |
115,730,435 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6422:Gcn1
|
UTSW |
5 |
115,747,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6435:Gcn1
|
UTSW |
5 |
115,749,081 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6607:Gcn1
|
UTSW |
5 |
115,747,537 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6724:Gcn1
|
UTSW |
5 |
115,747,217 (GRCm39) |
splice site |
probably null |
|
|
R6861:Gcn1
|
UTSW |
5 |
115,749,108 (GRCm39) |
missense |
probably benign |
|
|
R6875:Gcn1
|
UTSW |
5 |
115,726,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6910:Gcn1
|
UTSW |
5 |
115,744,597 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6975:Gcn1
|
UTSW |
5 |
115,751,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7027:Gcn1
|
UTSW |
5 |
115,754,605 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7038:Gcn1
|
UTSW |
5 |
115,749,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7171:Gcn1
|
UTSW |
5 |
115,728,352 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7276:Gcn1
|
UTSW |
5 |
115,749,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7456:Gcn1
|
UTSW |
5 |
115,743,005 (GRCm39) |
nonsense |
probably null |
|
|
R7473:Gcn1
|
UTSW |
5 |
115,719,863 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7517:Gcn1
|
UTSW |
5 |
115,757,755 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7714:Gcn1
|
UTSW |
5 |
115,733,359 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7752:Gcn1
|
UTSW |
5 |
115,753,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7812:Gcn1
|
UTSW |
5 |
115,731,751 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7922:Gcn1
|
UTSW |
5 |
115,752,527 (GRCm39) |
missense |
probably benign |
|
|
R8070:Gcn1
|
UTSW |
5 |
115,727,057 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8218:Gcn1
|
UTSW |
5 |
115,719,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8329:Gcn1
|
UTSW |
5 |
115,747,921 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8413:Gcn1
|
UTSW |
5 |
115,717,698 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Gcn1
|
UTSW |
5 |
115,752,454 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8802:Gcn1
|
UTSW |
5 |
115,747,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8899:Gcn1
|
UTSW |
5 |
115,717,220 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8946:Gcn1
|
UTSW |
5 |
115,733,404 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8963:Gcn1
|
UTSW |
5 |
115,727,153 (GRCm39) |
missense |
probably benign |
0.25 |
|
R9006:Gcn1
|
UTSW |
5 |
115,719,566 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9163:Gcn1
|
UTSW |
5 |
115,742,944 (GRCm39) |
missense |
probably benign |
|
|
R9177:Gcn1
|
UTSW |
5 |
115,719,867 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9187:Gcn1
|
UTSW |
5 |
115,752,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Gcn1
|
UTSW |
5 |
115,733,098 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9541:Gcn1
|
UTSW |
5 |
115,754,416 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9574:Gcn1
|
UTSW |
5 |
115,713,341 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9630:Gcn1
|
UTSW |
5 |
115,741,349 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9651:Gcn1
|
UTSW |
5 |
115,747,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9761:Gcn1
|
UTSW |
5 |
115,729,064 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9765:Gcn1
|
UTSW |
5 |
115,735,131 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Gcn1
|
UTSW |
5 |
115,752,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1191:Gcn1
|
UTSW |
5 |
115,713,352 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATTGTCCTCCTTCCACATGGG -3'
(R):5'- TTGACATTCTCCTGCGAAGGC -3'
Sequencing Primer
(F):5'- CTTCCACATGGGGCGCC -3'
(R):5'- GCAATGCTGCCCGCTTAC -3'
|
| Posted On |
2014-09-18 |
Incidental Mutation