Incidental Mutation 'R8121:Arhgap45'
| ID |
631511 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap45
|
| Ensembl Gene |
ENSMUSG00000035697 |
| Gene Name |
Rho GTPase activating protein 45 |
| Synonyms |
6330406L22Rik, Hmha1 |
| MMRRC Submission |
067550-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8121 (G1)
|
| Quality Score |
150.008 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
79852505-79867305 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 79853909 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 141
(E141G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043311]
[ENSMUST00000043866]
[ENSMUST00000099501]
[ENSMUST00000105373]
[ENSMUST00000132517]
[ENSMUST00000171637]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043311
|
| SMART Domains |
Protein: ENSMUSP00000041019
Gene: ENSMUSG00000035697
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
142 |
153 |
N/A |
INTRINSIC |
|
FCH
|
157 |
244 |
4.14e-17 |
SMART |
|
low complexity region
|
255 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
330 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
536 |
N/A |
INTRINSIC |
|
C1
|
582 |
628 |
3.15e-8 |
SMART |
|
RhoGAP
|
653 |
852 |
2.73e-73 |
SMART |
|
low complexity region
|
856 |
869 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
876 |
999 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043866
|
| SMART Domains |
Protein: ENSMUSP00000043090
Gene: ENSMUSG00000035722
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
23 |
42 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
515 |
747 |
1.1e-17 |
PFAM |
|
AAA
|
830 |
1011 |
4.97e-12 |
SMART |
|
low complexity region
|
1136 |
1147 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1241 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1299 |
1309 |
N/A |
INTRINSIC |
|
low complexity region
|
1374 |
1390 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
1427 |
1764 |
9e-43 |
PFAM |
|
AAA
|
1833 |
2018 |
7.2e-9 |
SMART |
|
low complexity region
|
2120 |
2135 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099501
AA Change: E130G
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000097100
Gene: ENSMUSG00000035697
AA Change: E130G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
258 |
269 |
N/A |
INTRINSIC |
|
FCH
|
273 |
360 |
4.14e-17 |
SMART |
|
low complexity region
|
371 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
440 |
N/A |
INTRINSIC |
|
low complexity region
|
446 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
652 |
N/A |
INTRINSIC |
|
C1
|
698 |
744 |
3.15e-8 |
SMART |
|
RhoGAP
|
769 |
968 |
2.73e-73 |
SMART |
|
low complexity region
|
972 |
985 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
992 |
1115 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105373
AA Change: E141G
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000101012
Gene: ENSMUSG00000035697
AA Change: E141G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
269 |
280 |
N/A |
INTRINSIC |
|
FCH
|
284 |
371 |
4.14e-17 |
SMART |
|
low complexity region
|
382 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
654 |
663 |
N/A |
INTRINSIC |
|
C1
|
709 |
755 |
3.15e-8 |
SMART |
|
RhoGAP
|
780 |
979 |
2.73e-73 |
SMART |
|
low complexity region
|
983 |
996 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
1003 |
1126 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132517
|
| SMART Domains |
Protein: ENSMUSP00000115111
Gene: ENSMUSG00000035722
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
23 |
42 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
515 |
747 |
1.1e-17 |
PFAM |
|
AAA
|
830 |
1011 |
4.97e-12 |
SMART |
|
low complexity region
|
1136 |
1147 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1241 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1299 |
1309 |
N/A |
INTRINSIC |
|
low complexity region
|
1374 |
1390 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
1427 |
1764 |
9e-43 |
PFAM |
|
AAA
|
1833 |
2018 |
7.2e-9 |
SMART |
|
low complexity region
|
2120 |
2135 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171637
|
| SMART Domains |
Protein: ENSMUSP00000128121
Gene: ENSMUSG00000035722
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
23 |
42 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
517 |
747 |
2.8e-19 |
PFAM |
|
AAA
|
830 |
1011 |
4.97e-12 |
SMART |
|
low complexity region
|
1136 |
1147 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1249 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1307 |
1317 |
N/A |
INTRINSIC |
|
low complexity region
|
1382 |
1398 |
N/A |
INTRINSIC |
|
Pfam:ABC2_membrane_3
|
1426 |
1772 |
3.9e-47 |
PFAM |
|
AAA
|
1841 |
2026 |
7.2e-9 |
SMART |
|
low complexity region
|
2128 |
2143 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1086 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.1%
- 20x: 97.3%
|
| Validation Efficiency |
100% (60/60) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 62 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003E16Rik |
A |
T |
6: 83,138,893 (GRCm39) |
M273L |
probably benign |
Het |
| Abi3bp |
A |
T |
16: 56,452,241 (GRCm39) |
K912N |
unknown |
Het |
| Arfgap2 |
T |
C |
2: 91,096,028 (GRCm39) |
F62L |
probably benign |
Het |
| Atraid |
G |
A |
5: 31,211,642 (GRCm39) |
|
probably null |
Het |
| Cd101 |
G |
A |
3: 100,927,898 (GRCm39) |
A65V |
probably damaging |
Het |
| Cd177 |
A |
G |
7: 24,459,067 (GRCm39) |
V114A |
probably benign |
Het |
| Cdh6 |
T |
C |
15: 13,044,757 (GRCm39) |
N455S |
probably damaging |
Het |
| Cdk14 |
A |
T |
5: 5,277,195 (GRCm39) |
S145T |
possibly damaging |
Het |
| Ces1h |
T |
C |
8: 94,080,104 (GRCm39) |
E470G |
unknown |
Het |
| Cfap58 |
A |
G |
19: 48,017,543 (GRCm39) |
Y801C |
probably benign |
Het |
| Clec2d |
C |
T |
6: 129,161,847 (GRCm39) |
T160M |
probably benign |
Het |
| Cryz |
A |
G |
3: 154,327,382 (GRCm39) |
I269V |
probably benign |
Het |
| Ctdp1 |
A |
T |
18: 80,499,223 (GRCm39) |
Y240N |
probably damaging |
Het |
| Dapk1 |
A |
G |
13: 60,909,212 (GRCm39) |
Y1275C |
probably damaging |
Het |
| Dnah9 |
A |
G |
11: 65,908,201 (GRCm39) |
I2385T |
probably benign |
Het |
| Dpp8 |
A |
G |
9: 64,985,362 (GRCm39) |
M807V |
probably benign |
Het |
| Entpd3 |
T |
A |
9: 120,384,720 (GRCm39) |
I99N |
probably damaging |
Het |
| Fbxw11 |
A |
G |
11: 32,670,646 (GRCm39) |
E204G |
possibly damaging |
Het |
| Fscn1 |
T |
C |
5: 142,946,616 (GRCm39) |
M138T |
probably damaging |
Het |
| Gm5114 |
T |
A |
7: 39,057,552 (GRCm39) |
Q689L |
probably benign |
Het |
| Iqgap2 |
T |
C |
13: 95,861,076 (GRCm39) |
N350S |
probably benign |
Het |
| Kcnj10 |
T |
A |
1: 172,196,809 (GRCm39) |
C108S |
probably damaging |
Het |
| Krtap10-4 |
G |
A |
10: 77,662,840 (GRCm39) |
R13C |
unknown |
Het |
| Lmo7 |
T |
C |
14: 102,163,736 (GRCm39) |
I1527T |
unknown |
Het |
| Lrrc17 |
A |
G |
5: 21,775,329 (GRCm39) |
K297R |
probably benign |
Het |
| Ltb4r1 |
G |
A |
14: 56,005,579 (GRCm39) |
R294H |
probably damaging |
Het |
| Macc1 |
A |
G |
12: 119,410,324 (GRCm39) |
D364G |
probably damaging |
Het |
| Mavs |
A |
C |
2: 131,087,395 (GRCm39) |
T298P |
probably damaging |
Het |
| Myh8 |
G |
T |
11: 67,180,647 (GRCm39) |
A628S |
probably benign |
Het |
| Neurl4 |
A |
T |
11: 69,799,056 (GRCm39) |
|
probably null |
Het |
| Nicn1 |
C |
A |
9: 108,172,304 (GRCm39) |
T213K |
probably damaging |
Het |
| Nptx1 |
G |
A |
11: 119,433,492 (GRCm39) |
T369I |
probably damaging |
Het |
| Nt5c1a |
T |
C |
4: 123,102,235 (GRCm39) |
S54P |
probably damaging |
Het |
| Nup210l |
G |
A |
3: 90,022,428 (GRCm39) |
R132Q |
probably damaging |
Het |
| Or2b11 |
A |
T |
11: 59,461,870 (GRCm39) |
I232N |
probably damaging |
Het |
| Or4k41 |
A |
G |
2: 111,279,505 (GRCm39) |
T7A |
probably benign |
Het |
| Or4p18 |
A |
T |
2: 88,233,040 (GRCm39) |
F79L |
probably benign |
Het |
| Or7g22 |
G |
A |
9: 19,048,988 (GRCm39) |
G233E |
probably damaging |
Het |
| Pip5k1b |
A |
T |
19: 24,337,355 (GRCm39) |
I311N |
probably damaging |
Het |
| Pkdrej |
C |
T |
15: 85,699,655 (GRCm39) |
V2094I |
probably benign |
Het |
| Pla2g2f |
A |
G |
4: 138,479,621 (GRCm39) |
Y179H |
probably damaging |
Het |
| Plekha3 |
A |
T |
2: 76,516,992 (GRCm39) |
T115S |
probably damaging |
Het |
| Ppp4c |
A |
G |
7: 126,386,496 (GRCm39) |
L167P |
probably damaging |
Het |
| Pramel28 |
T |
A |
4: 143,691,611 (GRCm39) |
S371C |
probably benign |
Het |
| Rarg |
A |
G |
15: 102,148,393 (GRCm39) |
I238T |
probably damaging |
Het |
| Scn7a |
A |
T |
2: 66,531,203 (GRCm39) |
I558N |
probably damaging |
Het |
| Sema3a |
C |
A |
5: 13,649,215 (GRCm39) |
H655N |
probably damaging |
Het |
| Serpinb6c |
T |
C |
13: 34,064,201 (GRCm39) |
M285V |
probably benign |
Het |
| Setx |
T |
A |
2: 29,035,046 (GRCm39) |
S510R |
possibly damaging |
Het |
| Sgcz |
A |
G |
8: 37,990,457 (GRCm39) |
S299P |
probably damaging |
Het |
| Slc12a2 |
T |
A |
18: 58,032,403 (GRCm39) |
F368I |
probably benign |
Het |
| Slc7a9 |
C |
A |
7: 35,153,542 (GRCm39) |
T181K |
probably damaging |
Het |
| Slco2b1 |
G |
A |
7: 99,334,760 (GRCm39) |
T237M |
probably benign |
Het |
| Spg11 |
A |
G |
2: 121,900,348 (GRCm39) |
|
probably null |
Het |
| Tbc1d22b |
G |
T |
17: 29,791,945 (GRCm39) |
G225V |
probably damaging |
Het |
| Tbcd |
A |
G |
11: 121,487,969 (GRCm39) |
|
probably null |
Het |
| Unc93a |
T |
C |
17: 13,328,560 (GRCm39) |
Y431C |
probably benign |
Het |
| Vmn1r65 |
C |
T |
7: 6,011,464 (GRCm39) |
V257I |
possibly damaging |
Het |
| Vmn2r124 |
A |
T |
17: 18,282,433 (GRCm39) |
T154S |
probably benign |
Het |
| Wnk2 |
A |
T |
13: 49,214,415 (GRCm39) |
L1487* |
probably null |
Het |
| Zfp853 |
G |
A |
5: 143,274,018 (GRCm39) |
A549V |
probably damaging |
Het |
| Zfp936 |
C |
T |
7: 42,839,547 (GRCm39) |
T338I |
possibly damaging |
Het |
|
| Other mutations in Arhgap45 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01360:Arhgap45
|
APN |
10 |
79,864,482 (GRCm39) |
splice site |
probably benign |
|
|
IGL01414:Arhgap45
|
APN |
10 |
79,862,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01505:Arhgap45
|
APN |
10 |
79,862,376 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02203:Arhgap45
|
APN |
10 |
79,863,387 (GRCm39) |
nonsense |
probably null |
|
|
IGL02557:Arhgap45
|
APN |
10 |
79,857,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arhgap45
|
APN |
10 |
79,853,768 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03292:Arhgap45
|
APN |
10 |
79,856,803 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03352:Arhgap45
|
APN |
10 |
79,866,585 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Celt
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
celtic
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
druid
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
Mistletoe
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
Roman
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stonehenge
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03048:Arhgap45
|
UTSW |
10 |
79,852,851 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4677001:Arhgap45
|
UTSW |
10 |
79,856,583 (GRCm39) |
missense |
probably benign |
|
|
R0532:Arhgap45
|
UTSW |
10 |
79,857,917 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1233:Arhgap45
|
UTSW |
10 |
79,863,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Arhgap45
|
UTSW |
10 |
79,864,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1666:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1668:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1688:Arhgap45
|
UTSW |
10 |
79,864,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Arhgap45
|
UTSW |
10 |
79,853,932 (GRCm39) |
nonsense |
probably null |
|
|
R1902:Arhgap45
|
UTSW |
10 |
79,861,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1912:Arhgap45
|
UTSW |
10 |
79,856,524 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1935:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1955:Arhgap45
|
UTSW |
10 |
79,862,326 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1968:Arhgap45
|
UTSW |
10 |
79,863,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1977:Arhgap45
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Arhgap45
|
UTSW |
10 |
79,856,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2074:Arhgap45
|
UTSW |
10 |
79,863,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2081:Arhgap45
|
UTSW |
10 |
79,863,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2162:Arhgap45
|
UTSW |
10 |
79,852,813 (GRCm39) |
start codon destroyed |
probably null |
0.02 |
|
R2937:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Arhgap45
|
UTSW |
10 |
79,862,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4695:Arhgap45
|
UTSW |
10 |
79,861,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4736:Arhgap45
|
UTSW |
10 |
79,862,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4758:Arhgap45
|
UTSW |
10 |
79,866,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Arhgap45
|
UTSW |
10 |
79,856,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4943:Arhgap45
|
UTSW |
10 |
79,862,337 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5102:Arhgap45
|
UTSW |
10 |
79,857,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5128:Arhgap45
|
UTSW |
10 |
79,866,793 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5667:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5920:Arhgap45
|
UTSW |
10 |
79,864,965 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5998:Arhgap45
|
UTSW |
10 |
79,866,784 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6276:Arhgap45
|
UTSW |
10 |
79,862,068 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6675:Arhgap45
|
UTSW |
10 |
79,853,938 (GRCm39) |
missense |
probably null |
0.98 |
|
R6738:Arhgap45
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6783:Arhgap45
|
UTSW |
10 |
79,853,698 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6863:Arhgap45
|
UTSW |
10 |
79,853,616 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6978:Arhgap45
|
UTSW |
10 |
79,857,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7089:Arhgap45
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7215:Arhgap45
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7307:Arhgap45
|
UTSW |
10 |
79,865,016 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7308:Arhgap45
|
UTSW |
10 |
79,862,392 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7480:Arhgap45
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
R7481:Arhgap45
|
UTSW |
10 |
79,858,134 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7649:Arhgap45
|
UTSW |
10 |
79,866,835 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7652:Arhgap45
|
UTSW |
10 |
79,864,672 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7748:Arhgap45
|
UTSW |
10 |
79,852,766 (GRCm39) |
unclassified |
probably benign |
|
|
R7883:Arhgap45
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
R8169:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8170:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8175:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8178:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8186:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8187:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8687:Arhgap45
|
UTSW |
10 |
79,852,621 (GRCm39) |
unclassified |
probably benign |
|
|
R8866:Arhgap45
|
UTSW |
10 |
79,853,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Arhgap45
|
UTSW |
10 |
79,855,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9299:Arhgap45
|
UTSW |
10 |
79,862,565 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9412:Arhgap45
|
UTSW |
10 |
79,855,564 (GRCm39) |
start codon destroyed |
probably null |
0.66 |
|
R9579:Arhgap45
|
UTSW |
10 |
79,853,843 (GRCm39) |
missense |
probably benign |
|
|
R9629:Arhgap45
|
UTSW |
10 |
79,863,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Arhgap45
|
UTSW |
10 |
79,857,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0023:Arhgap45
|
UTSW |
10 |
79,866,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0063:Arhgap45
|
UTSW |
10 |
79,866,190 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,864,886 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,861,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGGGCACAGGGACACTC -3'
(R):5'- GAACTTTAGTTGACACATGCACTTC -3'
Sequencing Primer
(F):5'- GGCACAGGGACACTCAAAAGAC -3'
(R):5'- CTGGAACTCACTTTGTAGACCAGG -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation