Incidental Mutation 'R8169:Arhgap45'
| ID |
633980 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgap45
|
| Ensembl Gene |
ENSMUSG00000035697 |
| Gene Name |
Rho GTPase activating protein 45 |
| Synonyms |
6330406L22Rik, Hmha1 |
| MMRRC Submission |
067595-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R8169 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
79852505-79867305 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 79863706 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 819
(A819T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043311]
[ENSMUST00000099501]
[ENSMUST00000105373]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000043311
AA Change: A692T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000041019
Gene: ENSMUSG00000035697
AA Change: A692T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
142 |
153 |
N/A |
INTRINSIC |
|
FCH
|
157 |
244 |
4.14e-17 |
SMART |
|
low complexity region
|
255 |
269 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
330 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
527 |
536 |
N/A |
INTRINSIC |
|
C1
|
582 |
628 |
3.15e-8 |
SMART |
|
RhoGAP
|
653 |
852 |
2.73e-73 |
SMART |
|
low complexity region
|
856 |
869 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
876 |
999 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099501
AA Change: A808T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000097100
Gene: ENSMUSG00000035697
AA Change: A808T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
258 |
269 |
N/A |
INTRINSIC |
|
FCH
|
273 |
360 |
4.14e-17 |
SMART |
|
low complexity region
|
371 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
440 |
N/A |
INTRINSIC |
|
low complexity region
|
446 |
461 |
N/A |
INTRINSIC |
|
low complexity region
|
643 |
652 |
N/A |
INTRINSIC |
|
C1
|
698 |
744 |
3.15e-8 |
SMART |
|
RhoGAP
|
769 |
968 |
2.73e-73 |
SMART |
|
low complexity region
|
972 |
985 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
992 |
1115 |
1e-21 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105373
AA Change: A819T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000101012
Gene: ENSMUSG00000035697
AA Change: A819T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
269 |
280 |
N/A |
INTRINSIC |
|
FCH
|
284 |
371 |
4.14e-17 |
SMART |
|
low complexity region
|
382 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
451 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
654 |
663 |
N/A |
INTRINSIC |
|
C1
|
709 |
755 |
3.15e-8 |
SMART |
|
RhoGAP
|
780 |
979 |
2.73e-73 |
SMART |
|
low complexity region
|
983 |
996 |
N/A |
INTRINSIC |
|
Blast:RhoGAP
|
1003 |
1126 |
1e-21 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
99% (80/81) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 3110082I17Rik |
C |
A |
5: 139,349,812 (GRCm39) |
G79V |
probably damaging |
Het |
| 4930562C15Rik |
T |
A |
16: 4,684,082 (GRCm39) |
Y226N |
probably benign |
Het |
| Bach1 |
G |
A |
16: 87,519,390 (GRCm39) |
C560Y |
possibly damaging |
Het |
| Capn13 |
T |
A |
17: 73,633,467 (GRCm39) |
|
probably null |
Het |
| Casq2 |
G |
T |
3: 102,017,628 (GRCm39) |
A103S |
possibly damaging |
Het |
| Cfap100 |
A |
G |
6: 90,394,656 (GRCm39) |
F57S |
|
Het |
| Clca3a2 |
A |
T |
3: 144,783,653 (GRCm39) |
L654Q |
probably damaging |
Het |
| Cntnap5c |
T |
A |
17: 58,411,765 (GRCm39) |
|
probably null |
Het |
| Cplane2 |
A |
G |
4: 140,945,530 (GRCm39) |
H127R |
probably damaging |
Het |
| Crtc2 |
G |
C |
3: 90,170,883 (GRCm39) |
G652A |
probably damaging |
Het |
| Csnk1g2 |
A |
G |
10: 80,475,636 (GRCm39) |
D401G |
probably damaging |
Het |
| Dars1 |
T |
C |
1: 128,304,002 (GRCm39) |
N242D |
probably null |
Het |
| Dnah10 |
T |
C |
5: 124,877,946 (GRCm39) |
L2677P |
probably damaging |
Het |
| Dnal1 |
G |
A |
12: 84,171,330 (GRCm39) |
A3T |
probably benign |
Het |
| Dpep2 |
C |
T |
8: 106,722,849 (GRCm39) |
V60I |
|
Het |
| Eeig1 |
T |
C |
2: 32,453,760 (GRCm39) |
I203T |
probably benign |
Het |
| Ehmt2 |
T |
A |
17: 35,122,339 (GRCm39) |
I302N |
probably benign |
Het |
| Eif3a |
C |
T |
19: 60,750,628 (GRCm39) |
R1309Q |
unknown |
Het |
| Eno4 |
T |
A |
19: 58,935,084 (GRCm39) |
Y100N |
probably benign |
Het |
| Ephx2 |
A |
T |
14: 66,349,602 (GRCm39) |
|
probably null |
Het |
| Fbxw14 |
A |
T |
9: 109,106,284 (GRCm39) |
I251K |
probably benign |
Het |
| Fcgbp |
T |
C |
7: 27,784,919 (GRCm39) |
|
probably null |
Het |
| Foxm1 |
A |
C |
6: 128,348,671 (GRCm39) |
|
probably null |
Het |
| Fscn3 |
T |
A |
6: 28,430,328 (GRCm39) |
I166N |
possibly damaging |
Het |
| Gdpd4 |
G |
T |
7: 97,621,335 (GRCm39) |
V193L |
probably benign |
Het |
| Gnpat |
T |
G |
8: 125,606,869 (GRCm39) |
C352G |
probably benign |
Het |
| H2-Q7 |
T |
A |
17: 35,658,910 (GRCm39) |
Y120* |
probably null |
Het |
| Klri1 |
G |
A |
6: 129,694,070 (GRCm39) |
R6C |
probably benign |
Het |
| Kmo |
T |
C |
1: 175,476,729 (GRCm39) |
V154A |
probably benign |
Het |
| Kmt2c |
A |
G |
5: 25,559,685 (GRCm39) |
L1031P |
probably damaging |
Het |
| Lrrc14b |
T |
G |
13: 74,511,286 (GRCm39) |
T265P |
possibly damaging |
Het |
| Lrrc2 |
C |
T |
9: 110,809,954 (GRCm39) |
T330I |
probably benign |
Het |
| Lyn |
T |
A |
4: 3,783,050 (GRCm39) |
S428T |
probably damaging |
Het |
| Lypd10 |
T |
A |
7: 24,412,000 (GRCm39) |
M60K |
probably benign |
Het |
| Mfsd8 |
T |
A |
3: 40,791,550 (GRCm39) |
M59L |
probably benign |
Het |
| Mok |
T |
A |
12: 110,774,799 (GRCm39) |
Q341L |
probably benign |
Het |
| Muc21 |
T |
C |
17: 35,932,072 (GRCm39) |
T705A |
unknown |
Het |
| Myh3 |
C |
A |
11: 66,979,856 (GRCm39) |
N598K |
probably benign |
Het |
| Nbeal1 |
G |
C |
1: 60,276,310 (GRCm39) |
V684L |
probably benign |
Het |
| Nlrp4e |
A |
G |
7: 23,019,931 (GRCm39) |
I139M |
probably benign |
Het |
| Or11g25 |
T |
C |
14: 50,723,692 (GRCm39) |
V259A |
probably benign |
Het |
| Or3a10 |
T |
A |
11: 73,935,707 (GRCm39) |
Q131L |
possibly damaging |
Het |
| Or4b13 |
G |
A |
2: 90,082,442 (GRCm39) |
R297* |
probably null |
Het |
| Or51g2 |
A |
G |
7: 102,622,545 (GRCm39) |
L218P |
probably damaging |
Het |
| Or52n2b |
A |
T |
7: 104,565,619 (GRCm39) |
Y295N |
possibly damaging |
Het |
| Osbpl7 |
G |
A |
11: 96,945,676 (GRCm39) |
S312N |
probably damaging |
Het |
| Paxip1 |
A |
G |
5: 27,977,093 (GRCm39) |
L323P |
unknown |
Het |
| Pcdh18 |
T |
A |
3: 49,699,684 (GRCm39) |
H926L |
probably damaging |
Het |
| Pcm1 |
T |
G |
8: 41,763,153 (GRCm39) |
S1460R |
possibly damaging |
Het |
| Pdha2 |
A |
G |
3: 140,917,155 (GRCm39) |
S118P |
possibly damaging |
Het |
| Pdss1 |
A |
T |
2: 22,791,824 (GRCm39) |
Y86F |
probably benign |
Het |
| Ppargc1a |
A |
T |
5: 51,631,026 (GRCm39) |
D534E |
probably benign |
Het |
| Prune2 |
A |
G |
19: 17,102,455 (GRCm39) |
K2538R |
probably benign |
Het |
| Ptprq |
A |
T |
10: 107,418,351 (GRCm39) |
I1675N |
probably damaging |
Het |
| Rgma |
C |
T |
7: 73,025,630 (GRCm39) |
P3L |
probably benign |
Het |
| Ros1 |
A |
G |
10: 51,940,768 (GRCm39) |
|
probably null |
Het |
| Sema4g |
C |
T |
19: 44,987,410 (GRCm39) |
R519W |
probably damaging |
Het |
| Serpinc1 |
T |
A |
1: 160,820,971 (GRCm39) |
F139L |
probably damaging |
Het |
| Slc22a29 |
A |
G |
19: 8,184,696 (GRCm39) |
I198T |
probably damaging |
Het |
| Slc4a5 |
T |
C |
6: 83,280,373 (GRCm39) |
V1007A |
probably benign |
Het |
| Sptbn1 |
T |
C |
11: 30,147,783 (GRCm39) |
Y17C |
possibly damaging |
Het |
| Tex261 |
C |
A |
6: 83,751,999 (GRCm39) |
|
probably null |
Het |
| Timmdc1 |
T |
A |
16: 38,331,148 (GRCm39) |
T128S |
probably benign |
Het |
| Tmem120b |
C |
A |
5: 123,237,999 (GRCm39) |
Y96* |
probably null |
Het |
| Tmem196 |
T |
A |
12: 119,982,311 (GRCm39) |
F182I |
possibly damaging |
Het |
| Tnxb |
G |
A |
17: 34,918,181 (GRCm39) |
V2365M |
possibly damaging |
Het |
| Tph1 |
T |
C |
7: 46,303,233 (GRCm39) |
|
silent |
Het |
| Trmt9b |
A |
T |
8: 36,978,857 (GRCm39) |
K153N |
probably damaging |
Het |
| Trpc1 |
G |
A |
9: 95,592,323 (GRCm39) |
Q551* |
probably null |
Het |
| Tubgcp3 |
T |
C |
8: 12,666,099 (GRCm39) |
N828D |
probably benign |
Het |
| Unc13a |
C |
A |
8: 72,108,933 (GRCm39) |
G478W |
probably damaging |
Het |
| Usp15 |
T |
A |
10: 122,961,798 (GRCm39) |
T627S |
|
Het |
| Vmn1r115 |
A |
T |
7: 20,578,144 (GRCm39) |
I256N |
probably damaging |
Het |
| Vmn2r6 |
T |
A |
3: 64,447,310 (GRCm39) |
K585N |
probably benign |
Het |
| Vsir |
G |
T |
10: 60,194,047 (GRCm39) |
|
probably null |
Het |
| Xirp2 |
A |
G |
2: 67,343,543 (GRCm39) |
D1928G |
probably benign |
Het |
| Xylt1 |
A |
G |
7: 117,249,846 (GRCm39) |
Y672C |
probably damaging |
Het |
| Yrdc |
A |
G |
4: 124,744,880 (GRCm39) |
S105G |
probably benign |
Het |
| Zfc3h1 |
T |
A |
10: 115,254,616 (GRCm39) |
N1403K |
probably damaging |
Het |
| Zfp160 |
A |
T |
17: 21,247,298 (GRCm39) |
H616L |
probably damaging |
Het |
| Zfp637 |
T |
A |
6: 117,822,252 (GRCm39) |
F127I |
probably damaging |
Het |
| Zfp69 |
G |
T |
4: 120,787,731 (GRCm39) |
A528D |
probably damaging |
Het |
| Zpr1 |
T |
A |
9: 46,189,645 (GRCm39) |
L342Q |
possibly damaging |
Het |
|
| Other mutations in Arhgap45 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01360:Arhgap45
|
APN |
10 |
79,864,482 (GRCm39) |
splice site |
probably benign |
|
|
IGL01414:Arhgap45
|
APN |
10 |
79,862,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01505:Arhgap45
|
APN |
10 |
79,862,376 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02203:Arhgap45
|
APN |
10 |
79,863,387 (GRCm39) |
nonsense |
probably null |
|
|
IGL02557:Arhgap45
|
APN |
10 |
79,857,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arhgap45
|
APN |
10 |
79,853,768 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL03292:Arhgap45
|
APN |
10 |
79,856,803 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03352:Arhgap45
|
APN |
10 |
79,866,585 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Celt
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
celtic
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
druid
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
Mistletoe
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
Roman
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stonehenge
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03048:Arhgap45
|
UTSW |
10 |
79,852,851 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4677001:Arhgap45
|
UTSW |
10 |
79,856,583 (GRCm39) |
missense |
probably benign |
|
|
R0532:Arhgap45
|
UTSW |
10 |
79,857,917 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1233:Arhgap45
|
UTSW |
10 |
79,863,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Arhgap45
|
UTSW |
10 |
79,864,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1666:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1668:Arhgap45
|
UTSW |
10 |
79,864,584 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1688:Arhgap45
|
UTSW |
10 |
79,864,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Arhgap45
|
UTSW |
10 |
79,853,932 (GRCm39) |
nonsense |
probably null |
|
|
R1902:Arhgap45
|
UTSW |
10 |
79,861,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1912:Arhgap45
|
UTSW |
10 |
79,856,524 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1935:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1936:Arhgap45
|
UTSW |
10 |
79,866,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1955:Arhgap45
|
UTSW |
10 |
79,862,326 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1968:Arhgap45
|
UTSW |
10 |
79,863,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1977:Arhgap45
|
UTSW |
10 |
79,856,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Arhgap45
|
UTSW |
10 |
79,856,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2074:Arhgap45
|
UTSW |
10 |
79,863,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2081:Arhgap45
|
UTSW |
10 |
79,863,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2162:Arhgap45
|
UTSW |
10 |
79,852,813 (GRCm39) |
start codon destroyed |
probably null |
0.02 |
|
R2937:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Arhgap45
|
UTSW |
10 |
79,864,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3081:Arhgap45
|
UTSW |
10 |
79,862,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4695:Arhgap45
|
UTSW |
10 |
79,861,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4736:Arhgap45
|
UTSW |
10 |
79,862,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4758:Arhgap45
|
UTSW |
10 |
79,866,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4860:Arhgap45
|
UTSW |
10 |
79,862,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Arhgap45
|
UTSW |
10 |
79,856,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4943:Arhgap45
|
UTSW |
10 |
79,862,337 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5102:Arhgap45
|
UTSW |
10 |
79,857,262 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5128:Arhgap45
|
UTSW |
10 |
79,866,793 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5667:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5671:Arhgap45
|
UTSW |
10 |
79,861,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5920:Arhgap45
|
UTSW |
10 |
79,864,965 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5998:Arhgap45
|
UTSW |
10 |
79,866,784 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6276:Arhgap45
|
UTSW |
10 |
79,862,068 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6675:Arhgap45
|
UTSW |
10 |
79,853,938 (GRCm39) |
missense |
probably null |
0.98 |
|
R6738:Arhgap45
|
UTSW |
10 |
79,863,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6783:Arhgap45
|
UTSW |
10 |
79,853,698 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6863:Arhgap45
|
UTSW |
10 |
79,853,616 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6978:Arhgap45
|
UTSW |
10 |
79,857,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7089:Arhgap45
|
UTSW |
10 |
79,862,181 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7215:Arhgap45
|
UTSW |
10 |
79,861,316 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7307:Arhgap45
|
UTSW |
10 |
79,865,016 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7308:Arhgap45
|
UTSW |
10 |
79,862,392 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7480:Arhgap45
|
UTSW |
10 |
79,862,936 (GRCm39) |
nonsense |
probably null |
|
|
R7481:Arhgap45
|
UTSW |
10 |
79,858,134 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7649:Arhgap45
|
UTSW |
10 |
79,866,835 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7652:Arhgap45
|
UTSW |
10 |
79,864,672 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7748:Arhgap45
|
UTSW |
10 |
79,852,766 (GRCm39) |
unclassified |
probably benign |
|
|
R7883:Arhgap45
|
UTSW |
10 |
79,863,423 (GRCm39) |
nonsense |
probably null |
|
|
R8121:Arhgap45
|
UTSW |
10 |
79,853,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8170:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8175:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8178:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8186:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8187:Arhgap45
|
UTSW |
10 |
79,863,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8687:Arhgap45
|
UTSW |
10 |
79,852,621 (GRCm39) |
unclassified |
probably benign |
|
|
R8866:Arhgap45
|
UTSW |
10 |
79,853,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8905:Arhgap45
|
UTSW |
10 |
79,855,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9299:Arhgap45
|
UTSW |
10 |
79,862,565 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9412:Arhgap45
|
UTSW |
10 |
79,855,564 (GRCm39) |
start codon destroyed |
probably null |
0.66 |
|
R9579:Arhgap45
|
UTSW |
10 |
79,853,843 (GRCm39) |
missense |
probably benign |
|
|
R9629:Arhgap45
|
UTSW |
10 |
79,863,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Arhgap45
|
UTSW |
10 |
79,857,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0023:Arhgap45
|
UTSW |
10 |
79,866,634 (GRCm39) |
missense |
probably damaging |
0.98 |
|
X0063:Arhgap45
|
UTSW |
10 |
79,866,190 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,864,886 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Arhgap45
|
UTSW |
10 |
79,861,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGGGTGCCCTTCATTGTC -3'
(R):5'- TAGCAAACTCACAGTAGAGGCC -3'
Sequencing Primer
(F):5'- AAAATGTGTCTGTGAGATTGAGC -3'
(R):5'- AGTAGAGGCCCATCCAGC -3'
|
| Posted On |
2020-07-13 |
Incidental Mutation