Incidental Mutation 'R8338:Ptprj'
| ID |
644717 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprj
|
| Ensembl Gene |
ENSMUSG00000025314 |
| Gene Name |
protein tyrosine phosphatase receptor type J |
| Synonyms |
Byp, RPTPJ, Scc1, CD148, DEP-1, Scc-1 |
| MMRRC Submission |
067730-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.223)
|
| Stock # |
R8338 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
90260098-90410939 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 90301481 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 217
(I217N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000129592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111493]
[ENSMUST00000111495]
[ENSMUST00000168621]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111493
AA Change: I31N
PolyPhen 2
Score 0.129 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000107119
Gene: ENSMUSG00000025314
AA Change: I31N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
46 |
N/A |
INTRINSIC |
|
FN3
|
47 |
182 |
3.76e-6 |
SMART |
|
FN3
|
194 |
271 |
4.56e-5 |
SMART |
|
FN3
|
282 |
357 |
5.32e-6 |
SMART |
|
FN3
|
368 |
446 |
2.19e-7 |
SMART |
|
FN3
|
455 |
531 |
5e-2 |
SMART |
|
FN3
|
546 |
628 |
2.77e1 |
SMART |
|
low complexity region
|
637 |
650 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
714 |
797 |
8e-26 |
BLAST |
|
PTPc
|
867 |
1127 |
3.37e-133 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111495
AA Change: I124N
PolyPhen 2
Score 0.479 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000107121
Gene: ENSMUSG00000025314
AA Change: I124N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
25 |
N/A |
INTRINSIC |
|
FN3
|
59 |
131 |
2.85e-6 |
SMART |
|
FN3
|
140 |
275 |
3.76e-6 |
SMART |
|
FN3
|
287 |
364 |
4.56e-5 |
SMART |
|
FN3
|
375 |
450 |
5.32e-6 |
SMART |
|
FN3
|
461 |
539 |
2.19e-7 |
SMART |
|
FN3
|
548 |
624 |
5e-2 |
SMART |
|
FN3
|
639 |
721 |
2.77e1 |
SMART |
|
low complexity region
|
730 |
743 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
807 |
890 |
1e-25 |
BLAST |
|
PTPc
|
960 |
1220 |
3.37e-133 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000168621
AA Change: I217N
PolyPhen 2
Score 0.479 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000129592
Gene: ENSMUSG00000025314
AA Change: I217N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
26 |
94 |
N/A |
INTRINSIC |
|
low complexity region
|
133 |
140 |
N/A |
INTRINSIC |
|
FN3
|
152 |
224 |
2.85e-6 |
SMART |
|
FN3
|
233 |
368 |
3.76e-6 |
SMART |
|
FN3
|
380 |
457 |
4.56e-5 |
SMART |
|
FN3
|
468 |
543 |
5.32e-6 |
SMART |
|
FN3
|
554 |
632 |
2.19e-7 |
SMART |
|
FN3
|
641 |
717 |
5e-2 |
SMART |
|
FN3
|
732 |
814 |
2.77e1 |
SMART |
|
low complexity region
|
823 |
836 |
N/A |
INTRINSIC |
|
Blast:PTPc
|
900 |
983 |
1e-25 |
BLAST |
|
PTPc
|
1053 |
1313 |
3.37e-133 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null allele die in utero displaying severe growth retardation and cardiovascular defects. Homozygotes for a second null allele are viable, fertile and healthy with no spontaneous tumor formation. Homozygotes for a third null allele show sterility and a block B cell development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ache |
T |
C |
5: 137,290,006 (GRCm39) |
L445P |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,253,018 (GRCm39) |
T1773I |
probably benign |
Het |
| Arap3 |
A |
G |
18: 38,106,683 (GRCm39) |
S1387P |
probably damaging |
Het |
| Bcl11a |
G |
C |
11: 24,114,578 (GRCm39) |
K640N |
probably damaging |
Het |
| Bicd1 |
G |
A |
6: 149,414,621 (GRCm39) |
V445I |
probably benign |
Het |
| Bltp3a |
A |
G |
17: 28,095,669 (GRCm39) |
N26S |
probably damaging |
Het |
| C2cd6 |
A |
C |
1: 59,099,734 (GRCm39) |
N402K |
probably benign |
Het |
| Celsr3 |
C |
T |
9: 108,704,539 (GRCm39) |
Q341* |
probably null |
Het |
| Cers1 |
A |
G |
8: 70,783,772 (GRCm39) |
E240G |
possibly damaging |
Het |
| Cfap157 |
G |
T |
2: 32,668,018 (GRCm39) |
T441N |
possibly damaging |
Het |
| Cfap44 |
G |
A |
16: 44,239,698 (GRCm39) |
|
probably null |
Het |
| Chd1 |
A |
G |
17: 15,990,242 (GRCm39) |
Y1598C |
probably damaging |
Het |
| Ckap2l |
T |
G |
2: 129,126,939 (GRCm39) |
Q413P |
probably damaging |
Het |
| Cobl |
T |
C |
11: 12,203,696 (GRCm39) |
E1002G |
probably benign |
Het |
| Cryge |
G |
A |
1: 65,087,933 (GRCm39) |
T156M |
unknown |
Het |
| Cubn |
A |
C |
2: 13,435,658 (GRCm39) |
F1099L |
probably benign |
Het |
| Cyp7b1 |
T |
C |
3: 18,151,730 (GRCm39) |
E161G |
probably benign |
Het |
| Dnah10 |
A |
G |
5: 124,909,566 (GRCm39) |
E4452G |
probably damaging |
Het |
| Dnah2 |
C |
T |
11: 69,378,122 (GRCm39) |
R1273Q |
probably damaging |
Het |
| Dnah3 |
T |
C |
7: 119,671,104 (GRCm39) |
E593G |
probably benign |
Het |
| Dnah9 |
C |
A |
11: 65,732,067 (GRCm39) |
|
probably null |
Het |
| Dnajc22 |
C |
A |
15: 98,999,022 (GRCm39) |
P69Q |
probably benign |
Het |
| Fam171a2 |
T |
A |
11: 102,329,172 (GRCm39) |
D529V |
probably benign |
Het |
| Fbxl17 |
T |
C |
17: 63,663,753 (GRCm39) |
I579V |
possibly damaging |
Het |
| Fry |
C |
T |
5: 150,282,516 (GRCm39) |
T347M |
probably damaging |
Het |
| Gm13272 |
A |
C |
4: 88,698,364 (GRCm39) |
D93A |
probably benign |
Het |
| Grm4 |
A |
T |
17: 27,653,977 (GRCm39) |
F658I |
probably damaging |
Het |
| Hmcn1 |
G |
A |
1: 150,614,485 (GRCm39) |
T1307I |
probably benign |
Het |
| Igkv12-98 |
G |
A |
6: 68,548,159 (GRCm39) |
S96N |
probably benign |
Het |
| Il2ra |
A |
T |
2: 11,687,885 (GRCm39) |
T222S |
probably benign |
Het |
| Il5ra |
G |
T |
6: 106,689,350 (GRCm39) |
T414K |
probably benign |
Het |
| Isg15 |
T |
A |
4: 156,284,088 (GRCm39) |
I147F |
probably benign |
Het |
| Kif14 |
C |
A |
1: 136,422,416 (GRCm39) |
A902E |
probably damaging |
Het |
| Lcat |
G |
A |
8: 106,666,719 (GRCm39) |
R268C |
probably damaging |
Het |
| Lipa |
T |
C |
19: 34,471,477 (GRCm39) |
N366S |
probably benign |
Het |
| Lrp4 |
A |
G |
2: 91,322,713 (GRCm39) |
T1101A |
probably benign |
Het |
| Man1a |
T |
A |
10: 53,801,643 (GRCm39) |
|
probably null |
Het |
| Mib1 |
A |
G |
18: 10,726,372 (GRCm39) |
D23G |
probably benign |
Het |
| Morc2b |
A |
T |
17: 33,355,387 (GRCm39) |
M795K |
probably benign |
Het |
| Msantd5f1 |
T |
A |
4: 73,605,435 (GRCm39) |
M282K |
possibly damaging |
Het |
| Mycbp2 |
T |
A |
14: 103,372,701 (GRCm39) |
E4048D |
probably damaging |
Het |
| Myo7b |
A |
G |
18: 32,104,408 (GRCm39) |
S1447P |
probably damaging |
Het |
| Myt1 |
A |
T |
2: 181,443,655 (GRCm39) |
T536S |
possibly damaging |
Het |
| Nod1 |
A |
T |
6: 54,920,956 (GRCm39) |
L454Q |
probably damaging |
Het |
| Nrf1 |
T |
A |
6: 30,140,247 (GRCm39) |
W199R |
|
Het |
| Or10w1 |
T |
A |
19: 13,632,216 (GRCm39) |
M141K |
possibly damaging |
Het |
| Or13a27 |
T |
A |
7: 139,925,306 (GRCm39) |
M199L |
probably benign |
Het |
| Or14c44 |
T |
C |
7: 86,061,702 (GRCm39) |
I44T |
probably benign |
Het |
| Or8k27 |
A |
T |
2: 86,275,729 (GRCm39) |
M199K |
probably benign |
Het |
| Or9a4 |
T |
C |
6: 40,548,910 (GRCm39) |
F197L |
probably benign |
Het |
| Ostn |
G |
T |
16: 27,143,285 (GRCm39) |
A38S |
probably benign |
Het |
| Paxbp1 |
A |
T |
16: 90,833,435 (GRCm39) |
D266E |
probably damaging |
Het |
| Pcdhb14 |
G |
T |
18: 37,582,175 (GRCm39) |
G427V |
probably damaging |
Het |
| Pdzrn3 |
A |
T |
6: 101,127,783 (GRCm39) |
M961K |
probably benign |
Het |
| Peg10 |
CCACATCAGGATCCACATCAGGATGCACATCAGCATCAGGATCCCCATCAGGATGCACATCAGGATCCACATCAGGATGCACATCAG |
CCACATCAGGATCCACATCAGGATGCACATCAG |
6: 4,756,398 (GRCm39) |
|
probably benign |
Het |
| Prdx5 |
T |
C |
19: 6,884,632 (GRCm39) |
D148G |
probably damaging |
Het |
| Rccd1 |
A |
T |
7: 79,970,618 (GRCm39) |
L54Q |
possibly damaging |
Het |
| Rfx6 |
T |
A |
10: 51,594,190 (GRCm39) |
V370E |
probably damaging |
Het |
| Sdr16c6 |
C |
T |
4: 4,076,620 (GRCm39) |
C93Y |
probably damaging |
Het |
| Shroom1 |
A |
G |
11: 53,354,107 (GRCm39) |
D9G |
probably benign |
Het |
| Snrpe |
A |
G |
1: 133,536,681 (GRCm39) |
V33A |
probably benign |
Het |
| Spats2 |
T |
A |
15: 99,076,340 (GRCm39) |
D139E |
probably damaging |
Het |
| Spopfm1 |
A |
G |
3: 94,173,285 (GRCm39) |
I94V |
possibly damaging |
Het |
| St18 |
A |
G |
1: 6,879,516 (GRCm39) |
E405G |
probably damaging |
Het |
| Strap |
A |
T |
6: 137,718,976 (GRCm39) |
E176V |
possibly damaging |
Het |
| Stxbp5l |
G |
T |
16: 36,994,718 (GRCm39) |
T729K |
probably damaging |
Het |
| Synj2bp |
G |
A |
12: 81,551,326 (GRCm39) |
Q97* |
probably null |
Het |
| Tbc1d32 |
T |
A |
10: 55,904,173 (GRCm39) |
Q1198L |
possibly damaging |
Het |
| Tmem98 |
T |
C |
11: 80,712,135 (GRCm39) |
S191P |
probably benign |
Het |
| Tnn |
C |
T |
1: 159,946,053 (GRCm39) |
G922R |
probably damaging |
Het |
| Treh |
A |
G |
9: 44,595,808 (GRCm39) |
N366S |
probably benign |
Het |
| Ttn |
T |
G |
2: 76,750,136 (GRCm39) |
S3638R |
probably benign |
Het |
| Uggt1 |
A |
G |
1: 36,266,602 (GRCm39) |
L124P |
probably damaging |
Het |
| V1rd19 |
A |
T |
7: 23,702,674 (GRCm39) |
K47* |
probably null |
Het |
| Wdhd1 |
T |
C |
14: 47,506,120 (GRCm39) |
M265V |
probably benign |
Het |
| Wsb1 |
T |
C |
11: 79,137,103 (GRCm39) |
D168G |
probably damaging |
Het |
|
| Other mutations in Ptprj |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01528:Ptprj
|
APN |
2 |
90,282,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01594:Ptprj
|
APN |
2 |
90,271,139 (GRCm39) |
splice site |
probably benign |
|
|
IGL01767:Ptprj
|
APN |
2 |
90,299,918 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01917:Ptprj
|
APN |
2 |
90,300,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01981:Ptprj
|
APN |
2 |
90,270,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02830:Ptprj
|
APN |
2 |
90,283,488 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02955:Ptprj
|
APN |
2 |
90,298,808 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03102:Ptprj
|
APN |
2 |
90,309,312 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03150:Ptprj
|
APN |
2 |
90,290,955 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03210:Ptprj
|
APN |
2 |
90,300,070 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02799:Ptprj
|
UTSW |
2 |
90,299,942 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0083:Ptprj
|
UTSW |
2 |
90,300,121 (GRCm39) |
splice site |
probably null |
|
|
R0108:Ptprj
|
UTSW |
2 |
90,300,121 (GRCm39) |
splice site |
probably null |
|
|
R0579:Ptprj
|
UTSW |
2 |
90,266,913 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1130:Ptprj
|
UTSW |
2 |
90,283,765 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1160:Ptprj
|
UTSW |
2 |
90,274,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1238:Ptprj
|
UTSW |
2 |
90,274,758 (GRCm39) |
splice site |
probably null |
|
|
R1507:Ptprj
|
UTSW |
2 |
90,301,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1552:Ptprj
|
UTSW |
2 |
90,301,497 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1607:Ptprj
|
UTSW |
2 |
90,293,664 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1693:Ptprj
|
UTSW |
2 |
90,280,141 (GRCm39) |
nonsense |
probably null |
|
|
R2016:Ptprj
|
UTSW |
2 |
90,294,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2017:Ptprj
|
UTSW |
2 |
90,294,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2044:Ptprj
|
UTSW |
2 |
90,293,439 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2322:Ptprj
|
UTSW |
2 |
90,301,473 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2516:Ptprj
|
UTSW |
2 |
90,305,340 (GRCm39) |
splice site |
probably benign |
|
|
R3106:Ptprj
|
UTSW |
2 |
90,270,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3964:Ptprj
|
UTSW |
2 |
90,298,785 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4201:Ptprj
|
UTSW |
2 |
90,293,439 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4533:Ptprj
|
UTSW |
2 |
90,270,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4680:Ptprj
|
UTSW |
2 |
90,290,840 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4738:Ptprj
|
UTSW |
2 |
90,270,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4983:Ptprj
|
UTSW |
2 |
90,290,876 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5137:Ptprj
|
UTSW |
2 |
90,299,992 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5349:Ptprj
|
UTSW |
2 |
90,301,605 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5369:Ptprj
|
UTSW |
2 |
90,299,985 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5718:Ptprj
|
UTSW |
2 |
90,288,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5914:Ptprj
|
UTSW |
2 |
90,283,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6022:Ptprj
|
UTSW |
2 |
90,301,667 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6341:Ptprj
|
UTSW |
2 |
90,288,693 (GRCm39) |
missense |
probably benign |
|
|
R6421:Ptprj
|
UTSW |
2 |
90,301,484 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6724:Ptprj
|
UTSW |
2 |
90,281,195 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6831:Ptprj
|
UTSW |
2 |
90,290,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6939:Ptprj
|
UTSW |
2 |
90,289,858 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6972:Ptprj
|
UTSW |
2 |
90,410,747 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7134:Ptprj
|
UTSW |
2 |
90,294,822 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7149:Ptprj
|
UTSW |
2 |
90,274,790 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7243:Ptprj
|
UTSW |
2 |
90,276,765 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7335:Ptprj
|
UTSW |
2 |
90,271,126 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7439:Ptprj
|
UTSW |
2 |
90,280,163 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7441:Ptprj
|
UTSW |
2 |
90,280,163 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7498:Ptprj
|
UTSW |
2 |
90,266,909 (GRCm39) |
nonsense |
probably null |
|
|
R7571:Ptprj
|
UTSW |
2 |
90,285,530 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7657:Ptprj
|
UTSW |
2 |
90,282,501 (GRCm39) |
splice site |
probably null |
|
|
R7672:Ptprj
|
UTSW |
2 |
90,290,940 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R7849:Ptprj
|
UTSW |
2 |
90,274,804 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7939:Ptprj
|
UTSW |
2 |
90,295,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7958:Ptprj
|
UTSW |
2 |
90,299,971 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8354:Ptprj
|
UTSW |
2 |
90,300,061 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8556:Ptprj
|
UTSW |
2 |
90,271,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8695:Ptprj
|
UTSW |
2 |
90,301,481 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8784:Ptprj
|
UTSW |
2 |
90,290,856 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8984:Ptprj
|
UTSW |
2 |
90,270,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9054:Ptprj
|
UTSW |
2 |
90,290,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9056:Ptprj
|
UTSW |
2 |
90,288,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9147:Ptprj
|
UTSW |
2 |
90,288,562 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9148:Ptprj
|
UTSW |
2 |
90,288,562 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9168:Ptprj
|
UTSW |
2 |
90,294,916 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9314:Ptprj
|
UTSW |
2 |
90,301,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9337:Ptprj
|
UTSW |
2 |
90,270,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9546:Ptprj
|
UTSW |
2 |
90,274,805 (GRCm39) |
missense |
probably benign |
0.08 |
|
RF013:Ptprj
|
UTSW |
2 |
90,301,514 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Ptprj
|
UTSW |
2 |
90,290,913 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTTGATATCCAGGACTATGGGATC -3'
(R):5'- TGTCGTCAGCCCAACTAGTG -3'
Sequencing Primer
(F):5'- CCTCGGGCTTTATGGAGAC -3'
(R):5'- GTCAGCCCAACTAGTGTGTTATTAAC -3'
|
| Posted On |
2020-09-02 |
Incidental Mutation