Incidental Mutation 'R9336:Myo15b'
| ID |
707181 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo15b
|
| Ensembl Gene |
ENSMUSG00000034427 |
| Gene Name |
myosin XVB |
| Synonyms |
LOC217328, LOC380737, E330039G21Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.069)
|
| Stock # |
R9336 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
115749232-115783429 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 115771064 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1654
(T1654A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091439
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040703]
[ENSMUST00000093911]
[ENSMUST00000222123]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000040703
|
| SMART Domains |
Protein: ENSMUSP00000048072
Gene: ENSMUSG00000034427
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
93 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
179 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
250 |
289 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
370 |
N/A |
INTRINSIC |
|
low complexity region
|
497 |
511 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
552 |
N/A |
INTRINSIC |
|
Blast:MYSc
|
587 |
775 |
3e-15 |
BLAST |
|
SH3
|
778 |
835 |
1.15e-7 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000091439
Gene: ENSMUSG00000034427
AA Change: T1654A
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
1 |
640 |
2.4e-134 |
SMART |
|
IQ
|
660 |
682 |
1.03e1 |
SMART |
|
Pfam:MyTH4
|
837 |
945 |
2.1e-23 |
PFAM |
|
low complexity region
|
1050 |
1068 |
N/A |
INTRINSIC |
|
low complexity region
|
1136 |
1170 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1246 |
N/A |
INTRINSIC |
|
low complexity region
|
1302 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1468 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1509 |
N/A |
INTRINSIC |
|
SH3
|
1735 |
1792 |
1.15e-7 |
SMART |
|
Pfam:MyTH4
|
1928 |
2029 |
8.3e-25 |
PFAM |
|
B41
|
2032 |
2235 |
6.99e-4 |
SMART |
|
low complexity region
|
2243 |
2253 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000222123
AA Change: T232A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2510039O18Rik |
C |
T |
4: 148,029,490 (GRCm39) |
R487C |
probably benign |
Het |
| 2900026A02Rik |
A |
T |
5: 113,240,966 (GRCm39) |
|
probably null |
Het |
| Adamts15 |
T |
A |
9: 30,816,085 (GRCm39) |
T625S |
probably damaging |
Het |
| Adamtsl1 |
T |
C |
4: 86,240,264 (GRCm39) |
V675A |
probably benign |
Het |
| Ank3 |
A |
T |
10: 69,809,578 (GRCm39) |
T1120S |
probably benign |
Het |
| Armh3 |
A |
T |
19: 45,945,120 (GRCm39) |
M277K |
probably damaging |
Het |
| Babam2 |
A |
T |
5: 31,859,194 (GRCm39) |
M1L |
possibly damaging |
Het |
| Cadm3 |
G |
A |
1: 173,168,786 (GRCm39) |
Q261* |
probably null |
Het |
| Cdc27 |
A |
T |
11: 104,396,496 (GRCm39) |
D802E |
probably benign |
Het |
| Cfap206 |
C |
T |
4: 34,716,494 (GRCm39) |
V324I |
probably benign |
Het |
| Cfap44 |
T |
C |
16: 44,242,807 (GRCm39) |
I737T |
probably damaging |
Het |
| Chrm3 |
A |
T |
13: 9,928,652 (GRCm39) |
I128N |
probably damaging |
Het |
| Cyfip1 |
T |
A |
7: 55,554,189 (GRCm39) |
S743T |
probably benign |
Het |
| Ddias |
A |
G |
7: 92,507,314 (GRCm39) |
V867A |
possibly damaging |
Het |
| Ddx20 |
G |
C |
3: 105,585,903 (GRCm39) |
T814R |
possibly damaging |
Het |
| Dgka |
A |
T |
10: 128,566,935 (GRCm39) |
|
probably null |
Het |
| Dnah9 |
A |
T |
11: 65,761,775 (GRCm39) |
V3905E |
probably damaging |
Het |
| Dsg3 |
C |
A |
18: 20,657,742 (GRCm39) |
Q271K |
probably benign |
Het |
| Dvl2 |
T |
A |
11: 69,897,180 (GRCm39) |
I294N |
probably damaging |
Het |
| E2f3 |
G |
A |
13: 30,095,239 (GRCm39) |
H350Y |
possibly damaging |
Het |
| Eif2b5 |
G |
A |
16: 20,324,027 (GRCm39) |
D457N |
probably damaging |
Het |
| Erbb3 |
T |
C |
10: 128,420,929 (GRCm39) |
T125A |
probably benign |
Het |
| Etv5 |
A |
C |
16: 22,254,627 (GRCm39) |
C78G |
probably benign |
Het |
| Frrs1 |
G |
A |
3: 116,684,582 (GRCm39) |
R263H |
probably benign |
Het |
| Grid1 |
G |
A |
14: 35,043,664 (GRCm39) |
D340N |
probably damaging |
Het |
| Hivep3 |
A |
T |
4: 119,952,400 (GRCm39) |
I239F |
possibly damaging |
Het |
| Ifi208 |
C |
T |
1: 173,510,394 (GRCm39) |
T183I |
probably damaging |
Het |
| Ifitm2 |
AG |
A |
7: 140,535,814 (GRCm39) |
|
probably null |
Het |
| Igkv1-88 |
T |
A |
6: 68,839,313 (GRCm39) |
I100F |
probably damaging |
Het |
| Kmt2c |
T |
C |
5: 25,614,165 (GRCm39) |
N185S |
probably benign |
Het |
| Kmt2d |
A |
C |
15: 98,743,697 (GRCm39) |
L3821R |
unknown |
Het |
| Krtap22-2 |
T |
G |
16: 88,807,478 (GRCm39) |
Y40S |
unknown |
Het |
| Lrrc1 |
A |
G |
9: 77,349,480 (GRCm39) |
V362A |
probably damaging |
Het |
| Malsu1 |
T |
A |
6: 49,061,449 (GRCm39) |
I171N |
probably damaging |
Het |
| Mark1 |
C |
T |
1: 184,648,345 (GRCm39) |
G314S |
possibly damaging |
Het |
| Mib2 |
T |
C |
4: 155,743,394 (GRCm39) |
N135S |
probably benign |
Het |
| Mos |
A |
T |
4: 3,870,886 (GRCm39) |
L310Q |
probably damaging |
Het |
| Muc4 |
C |
T |
16: 32,569,756 (GRCm39) |
T272I |
possibly damaging |
Het |
| Napsa |
G |
T |
7: 44,231,769 (GRCm39) |
G153W |
probably damaging |
Het |
| Nos3 |
A |
C |
5: 24,584,761 (GRCm39) |
I722L |
probably benign |
Het |
| Or10z1 |
A |
T |
1: 174,077,679 (GRCm39) |
D271E |
probably damaging |
Het |
| Or1p1c |
A |
T |
11: 74,160,743 (GRCm39) |
D176V |
probably damaging |
Het |
| Or51h1 |
A |
T |
7: 102,308,199 (GRCm39) |
H57L |
probably damaging |
Het |
| Or5b104 |
A |
T |
19: 13,072,513 (GRCm39) |
S166R |
probably benign |
Het |
| P4ha2 |
T |
A |
11: 54,002,390 (GRCm39) |
D109E |
possibly damaging |
Het |
| Pappa |
G |
T |
4: 65,042,918 (GRCm39) |
C47F |
unknown |
Het |
| Pbx3 |
T |
A |
2: 34,261,832 (GRCm39) |
H34L |
probably benign |
Het |
| Pcca |
A |
G |
14: 122,887,738 (GRCm39) |
T234A |
probably benign |
Het |
| Pcdha11 |
C |
T |
18: 37,144,514 (GRCm39) |
R202W |
probably damaging |
Het |
| Pcdhga1 |
T |
G |
18: 37,795,251 (GRCm39) |
V85G |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,726,562 (GRCm39) |
I1807V |
unknown |
Het |
| Pgm3 |
A |
T |
9: 86,437,413 (GRCm39) |
F528Y |
probably benign |
Het |
| Pigz |
T |
C |
16: 31,763,694 (GRCm39) |
Y251H |
probably damaging |
Het |
| Pik3c2g |
G |
T |
6: 139,821,161 (GRCm39) |
Q687H |
|
Het |
| Pja2 |
A |
T |
17: 64,590,432 (GRCm39) |
N700K |
unknown |
Het |
| Pkd2l2 |
T |
C |
18: 34,561,158 (GRCm39) |
F389L |
probably damaging |
Het |
| Plcz1 |
T |
A |
6: 139,985,446 (GRCm39) |
T32S |
possibly damaging |
Het |
| Pola2 |
A |
G |
19: 5,991,029 (GRCm39) |
V555A |
possibly damaging |
Het |
| Ppp4r3a |
A |
C |
12: 101,015,919 (GRCm39) |
C541G |
probably benign |
Het |
| Prr15l |
A |
T |
11: 96,825,599 (GRCm39) |
K76N |
probably damaging |
Het |
| Psg28 |
C |
A |
7: 18,156,905 (GRCm39) |
K443N |
possibly damaging |
Het |
| Ptch2 |
G |
T |
4: 116,954,197 (GRCm39) |
A76S |
probably damaging |
Het |
| Ptch2 |
A |
G |
4: 116,966,776 (GRCm39) |
D553G |
possibly damaging |
Het |
| Ptprz1 |
T |
C |
6: 23,000,855 (GRCm39) |
S982P |
probably benign |
Het |
| Rnd3 |
T |
C |
2: 51,038,844 (GRCm39) |
I15V |
probably benign |
Het |
| Rtn3 |
T |
C |
19: 7,460,328 (GRCm39) |
K41E |
unknown |
Het |
| Sap25 |
T |
C |
5: 137,639,985 (GRCm39) |
S30P |
probably benign |
Het |
| Scfd2 |
A |
T |
5: 74,692,006 (GRCm39) |
I92N |
probably damaging |
Het |
| Sdr16c5 |
T |
C |
4: 4,016,108 (GRCm39) |
Y106C |
probably damaging |
Het |
| Sell |
T |
C |
1: 163,893,177 (GRCm39) |
I131T |
probably damaging |
Het |
| Sesn3 |
T |
A |
9: 14,225,850 (GRCm39) |
V195D |
probably damaging |
Het |
| Setdb2 |
A |
G |
14: 59,660,816 (GRCm39) |
V109A |
unknown |
Het |
| Skint2 |
T |
C |
4: 112,483,054 (GRCm39) |
I153T |
probably benign |
Het |
| Slc22a1 |
A |
G |
17: 12,886,142 (GRCm39) |
S164P |
probably damaging |
Het |
| Sowahc |
G |
A |
10: 59,058,305 (GRCm39) |
G147D |
probably benign |
Het |
| Strip2 |
G |
C |
6: 29,931,824 (GRCm39) |
G456R |
probably benign |
Het |
| Synpo |
G |
T |
18: 60,735,472 (GRCm39) |
R825S |
probably damaging |
Het |
| Tango6 |
A |
G |
8: 107,415,701 (GRCm39) |
D174G |
probably benign |
Het |
| Tas1r2 |
T |
C |
4: 139,389,316 (GRCm39) |
F433S |
probably damaging |
Het |
| Tas2r126 |
T |
C |
6: 42,411,877 (GRCm39) |
S137P |
probably benign |
Het |
| Tbc1d15 |
A |
G |
10: 115,044,866 (GRCm39) |
F512S |
probably damaging |
Het |
| Tenm3 |
A |
T |
8: 48,870,115 (GRCm39) |
L226Q |
probably damaging |
Het |
| Tmod1 |
A |
G |
4: 46,078,368 (GRCm39) |
T59A |
probably damaging |
Het |
| Tmprss9 |
T |
A |
10: 80,730,787 (GRCm39) |
M771K |
probably benign |
Het |
| Trim29 |
T |
C |
9: 43,238,350 (GRCm39) |
Y485H |
possibly damaging |
Het |
| Ttc17 |
T |
C |
2: 94,189,198 (GRCm39) |
K144E |
probably benign |
Het |
| Ttc21b |
A |
G |
2: 66,057,287 (GRCm39) |
Y562H |
probably benign |
Het |
| Ugt2b5 |
T |
C |
5: 87,285,130 (GRCm39) |
H269R |
probably benign |
Het |
| Utp20 |
A |
G |
10: 88,649,798 (GRCm39) |
F471L |
probably damaging |
Het |
| Vmn2r120 |
T |
A |
17: 57,832,201 (GRCm39) |
D196V |
possibly damaging |
Het |
| Wdr72 |
T |
C |
9: 74,117,292 (GRCm39) |
V680A |
probably damaging |
Het |
| Wee1 |
G |
A |
7: 109,721,689 (GRCm39) |
G45S |
probably damaging |
Het |
| Zfp1006 |
A |
T |
8: 129,944,149 (GRCm39) |
D91E |
unknown |
Het |
| Zfp518a |
G |
A |
19: 40,901,225 (GRCm39) |
V385I |
probably benign |
Het |
|
| Other mutations in Myo15b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Myo15b
|
APN |
11 |
115,782,742 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01409:Myo15b
|
APN |
11 |
115,760,330 (GRCm39) |
nonsense |
probably null |
|
|
IGL01539:Myo15b
|
APN |
11 |
115,754,299 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01895:Myo15b
|
APN |
11 |
115,774,324 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02254:Myo15b
|
APN |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02343:Myo15b
|
APN |
11 |
115,764,226 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02349:Myo15b
|
APN |
11 |
115,753,931 (GRCm39) |
splice site |
probably benign |
|
|
IGL02368:Myo15b
|
APN |
11 |
115,767,828 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02576:Myo15b
|
APN |
11 |
115,780,879 (GRCm39) |
missense |
probably null |
0.97 |
|
IGL02650:Myo15b
|
APN |
11 |
115,777,337 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02661:Myo15b
|
APN |
11 |
115,774,895 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02716:Myo15b
|
APN |
11 |
115,774,535 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02733:Myo15b
|
APN |
11 |
115,775,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02951:Myo15b
|
APN |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03017:Myo15b
|
APN |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03029:Myo15b
|
APN |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
ANU74:Myo15b
|
UTSW |
11 |
115,769,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0092:Myo15b
|
UTSW |
11 |
115,753,812 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0255:Myo15b
|
UTSW |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0325:Myo15b
|
UTSW |
11 |
115,775,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Myo15b
|
UTSW |
11 |
115,773,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Myo15b
|
UTSW |
11 |
115,755,468 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0711:Myo15b
|
UTSW |
11 |
115,774,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0815:Myo15b
|
UTSW |
11 |
115,757,162 (GRCm39) |
splice site |
probably benign |
|
|
R0961:Myo15b
|
UTSW |
11 |
115,773,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1066:Myo15b
|
UTSW |
11 |
115,770,577 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1221:Myo15b
|
UTSW |
11 |
115,777,546 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1240:Myo15b
|
UTSW |
11 |
115,771,327 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1275:Myo15b
|
UTSW |
11 |
115,774,318 (GRCm39) |
small deletion |
probably benign |
|
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1317:Myo15b
|
UTSW |
11 |
115,774,460 (GRCm39) |
missense |
probably null |
0.14 |
|
R1491:Myo15b
|
UTSW |
11 |
115,777,683 (GRCm39) |
splice site |
probably null |
|
|
R1552:Myo15b
|
UTSW |
11 |
115,757,461 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1731:Myo15b
|
UTSW |
11 |
115,782,386 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1800:Myo15b
|
UTSW |
11 |
115,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1843:Myo15b
|
UTSW |
11 |
115,760,412 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Myo15b
|
UTSW |
11 |
115,773,080 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1934:Myo15b
|
UTSW |
11 |
115,754,310 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1939:Myo15b
|
UTSW |
11 |
115,778,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1945:Myo15b
|
UTSW |
11 |
115,769,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Myo15b
|
UTSW |
11 |
115,773,701 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2130:Myo15b
|
UTSW |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2138:Myo15b
|
UTSW |
11 |
115,774,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2176:Myo15b
|
UTSW |
11 |
115,757,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Myo15b
|
UTSW |
11 |
115,770,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Myo15b
|
UTSW |
11 |
115,755,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3620:Myo15b
|
UTSW |
11 |
115,762,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3716:Myo15b
|
UTSW |
11 |
115,754,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4013:Myo15b
|
UTSW |
11 |
115,762,282 (GRCm39) |
nonsense |
probably null |
|
|
R4021:Myo15b
|
UTSW |
11 |
115,764,331 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4119:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4120:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4499:Myo15b
|
UTSW |
11 |
115,781,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4653:Myo15b
|
UTSW |
11 |
115,770,813 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4655:Myo15b
|
UTSW |
11 |
115,781,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Myo15b
|
UTSW |
11 |
115,752,761 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4702:Myo15b
|
UTSW |
11 |
115,774,834 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4777:Myo15b
|
UTSW |
11 |
115,770,478 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4833:Myo15b
|
UTSW |
11 |
115,778,428 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5083:Myo15b
|
UTSW |
11 |
115,757,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5121:Myo15b
|
UTSW |
11 |
115,776,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5146:Myo15b
|
UTSW |
11 |
115,782,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5535:Myo15b
|
UTSW |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5647:Myo15b
|
UTSW |
11 |
115,762,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5849:Myo15b
|
UTSW |
11 |
115,772,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5882:Myo15b
|
UTSW |
11 |
115,760,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5956:Myo15b
|
UTSW |
11 |
115,764,583 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6273:Myo15b
|
UTSW |
11 |
115,753,625 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6302:Myo15b
|
UTSW |
11 |
115,777,065 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6318:Myo15b
|
UTSW |
11 |
115,781,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6462:Myo15b
|
UTSW |
11 |
115,750,268 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6792:Myo15b
|
UTSW |
11 |
115,775,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo15b
|
UTSW |
11 |
115,781,540 (GRCm39) |
splice site |
probably null |
|
|
R7015:Myo15b
|
UTSW |
11 |
115,762,670 (GRCm39) |
missense |
|
|
|
R7020:Myo15b
|
UTSW |
11 |
115,757,493 (GRCm39) |
nonsense |
probably null |
|
|
R7096:Myo15b
|
UTSW |
11 |
115,782,324 (GRCm39) |
splice site |
probably null |
|
|
R7219:Myo15b
|
UTSW |
11 |
115,767,921 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7400:Myo15b
|
UTSW |
11 |
115,750,939 (GRCm39) |
missense |
|
|
|
R7413:Myo15b
|
UTSW |
11 |
115,768,970 (GRCm39) |
missense |
|
|
|
R7483:Myo15b
|
UTSW |
11 |
115,749,570 (GRCm39) |
missense |
|
|
|
R7523:Myo15b
|
UTSW |
11 |
115,781,684 (GRCm39) |
missense |
unknown |
|
|
R7737:Myo15b
|
UTSW |
11 |
115,778,749 (GRCm39) |
missense |
unknown |
|
|
R7784:Myo15b
|
UTSW |
11 |
115,752,166 (GRCm39) |
missense |
|
|
|
R7842:Myo15b
|
UTSW |
11 |
115,762,321 (GRCm39) |
missense |
|
|
|
R7921:Myo15b
|
UTSW |
11 |
115,778,004 (GRCm39) |
nonsense |
probably null |
|
|
R8065:Myo15b
|
UTSW |
11 |
115,778,769 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8183:Myo15b
|
UTSW |
11 |
115,773,843 (GRCm39) |
splice site |
probably null |
|
|
R8193:Myo15b
|
UTSW |
11 |
115,775,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Myo15b
|
UTSW |
11 |
115,767,827 (GRCm39) |
missense |
|
|
|
R8430:Myo15b
|
UTSW |
11 |
115,773,049 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8482:Myo15b
|
UTSW |
11 |
115,774,083 (GRCm39) |
nonsense |
probably null |
|
|
R8515:Myo15b
|
UTSW |
11 |
115,749,610 (GRCm39) |
missense |
|
|
|
R8798:Myo15b
|
UTSW |
11 |
115,754,232 (GRCm39) |
missense |
|
|
|
R8937:Myo15b
|
UTSW |
11 |
115,773,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8975:Myo15b
|
UTSW |
11 |
115,781,780 (GRCm39) |
missense |
unknown |
|
|
R9045:Myo15b
|
UTSW |
11 |
115,783,178 (GRCm39) |
makesense |
probably null |
|
|
R9117:Myo15b
|
UTSW |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9185:Myo15b
|
UTSW |
11 |
115,771,255 (GRCm39) |
missense |
unknown |
|
|
R9226:Myo15b
|
UTSW |
11 |
115,750,924 (GRCm39) |
missense |
|
|
|
R9302:Myo15b
|
UTSW |
11 |
115,776,238 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9318:Myo15b
|
UTSW |
11 |
115,775,965 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9337:Myo15b
|
UTSW |
11 |
115,749,861 (GRCm39) |
missense |
|
|
|
R9338:Myo15b
|
UTSW |
11 |
115,762,238 (GRCm39) |
missense |
|
|
|
R9498:Myo15b
|
UTSW |
11 |
115,770,784 (GRCm39) |
missense |
|
|
|
R9500:Myo15b
|
UTSW |
11 |
115,777,466 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9602:Myo15b
|
UTSW |
11 |
115,769,269 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9642:Myo15b
|
UTSW |
11 |
115,772,335 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0020:Myo15b
|
UTSW |
11 |
115,762,625 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,778,751 (GRCm39) |
missense |
unknown |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,774,278 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATTTGTATCTGACCAGGCTCC -3'
(R):5'- GTGGTCCAGGATTCCACTTC -3'
Sequencing Primer
(F):5'- TATCTGACCAGGCTCCCAGTG -3'
(R):5'- ATTCCACTTCCGCGGAGTAG -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation