|Institutional Source||Beutler Lab|
|Gene Name||dipeptidase 3|
|Is this an essential gene?||Probably non essential (E-score: 0.091)|
|Stock #||R0422 (G1)|
|Chromosomal Location||105973513-105979429 bp(-) (GRCm38)|
|Type of Mutation||critical splice donor site (2 bp from exon)|
|DNA Base Change (assembly)||A to G at 105976118 bp|
|Amino Acid Change|
|Ref Sequence||ENSEMBL: ENSMUSP00000034371 (fasta)|
|Gene Model||predicted gene model for transcript(s): [ENSMUST00000034371]|
|Predicted Effect||probably null
|Predicted Effect||noncoding transcript
|Coding Region Coverage||
|MGI Phenotype||FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Allele List at MGI|
|Other mutations in this stock||
|Other mutations in Dpep3||
(F):5'- CAGTACGGAGCGGAGTTTATCGTC -3'
(R):5'- AGCAAGCACAATGGCAGTCCAG -3'
(F):5'- gccccaagttcaattcccag -3'
(R):5'- CAATGGCAGTCCAGAGGGTC -3'