Incidental Mutation 'R4858:Ccdc180'
| ID |
372210 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ccdc180
|
| Ensembl Gene |
ENSMUSG00000035539 |
| Gene Name |
coiled-coil domain containing 180 |
| Synonyms |
LOC381522, E230008N13Rik |
| MMRRC Submission |
042469-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4858 (G1)
|
| Quality Score |
181 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
45890303-45950774 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 45923244 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Serine
at position 1066
(I1066S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000136714
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000178561]
|
| AlphaFold |
J3QNE4 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000149903
AA Change: I890S
|
| SMART Domains |
Protein: ENSMUSP00000119784
Gene: ENSMUSG00000035539
AA Change: I890S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
42 |
N/A |
INTRINSIC |
|
coiled coil region
|
90 |
117 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
141 |
609 |
2e-189 |
PFAM |
|
low complexity region
|
628 |
642 |
N/A |
INTRINSIC |
|
low complexity region
|
658 |
675 |
N/A |
INTRINSIC |
|
coiled coil region
|
710 |
780 |
N/A |
INTRINSIC |
|
coiled coil region
|
945 |
979 |
N/A |
INTRINSIC |
|
low complexity region
|
1100 |
1123 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1169 |
1372 |
9.5e-77 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151024
|
| SMART Domains |
Protein: ENSMUSP00000122332
Gene: ENSMUSG00000035539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
22 |
N/A |
INTRINSIC |
|
low complexity region
|
38 |
55 |
N/A |
INTRINSIC |
|
coiled coil region
|
90 |
160 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000178561
AA Change: I1066S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000136714
Gene: ENSMUSG00000035539
AA Change: I1066S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
49 |
N/A |
INTRINSIC |
|
coiled coil region
|
98 |
125 |
N/A |
INTRINSIC |
|
Pfam:DUF4455
|
148 |
616 |
7.3e-189 |
PFAM |
|
low complexity region
|
635 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
682 |
N/A |
INTRINSIC |
|
coiled coil region
|
718 |
788 |
N/A |
INTRINSIC |
|
coiled coil region
|
1121 |
1155 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1298 |
N/A |
INTRINSIC |
|
Pfam:DUF4456
|
1344 |
1547 |
2.2e-76 |
PFAM |
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 96.0%
- 20x: 91.5%
|
| Validation Efficiency |
94% (103/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a coiled-coil domain. Alternative splicing results in multiple transcript variants encoding different isoforms. A single nucleotide polymorphism (SNP) in this gene has been associated with increased susceptibility to Behcet's Disease (PMID: 19442274). [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgb |
T |
C |
10: 10,225,321 (GRCm39) |
Y1415C |
probably damaging |
Het |
| Adgrf1 |
T |
C |
17: 43,614,563 (GRCm39) |
S216P |
probably damaging |
Het |
| Ankrd12 |
T |
C |
17: 66,338,428 (GRCm39) |
D197G |
probably damaging |
Het |
| Aoc3 |
C |
A |
11: 101,222,488 (GRCm39) |
H198Q |
probably damaging |
Het |
| Aox1 |
C |
A |
1: 58,143,640 (GRCm39) |
H1253N |
probably benign |
Het |
| Arg1 |
T |
A |
10: 24,798,536 (GRCm39) |
E38V |
possibly damaging |
Het |
| Baz2b |
T |
A |
2: 59,738,087 (GRCm39) |
M1741L |
probably benign |
Het |
| Bend4 |
T |
C |
5: 67,574,915 (GRCm39) |
E322G |
probably damaging |
Het |
| Brpf1 |
T |
C |
6: 113,294,639 (GRCm39) |
V661A |
possibly damaging |
Het |
| C2cd3 |
A |
T |
7: 100,104,160 (GRCm39) |
T2058S |
probably damaging |
Het |
| Camk4 |
T |
C |
18: 33,309,266 (GRCm39) |
V223A |
probably damaging |
Het |
| Casp1 |
C |
T |
9: 5,306,742 (GRCm39) |
R395C |
probably damaging |
Het |
| Ccne1 |
A |
G |
7: 37,798,744 (GRCm39) |
F292L |
probably damaging |
Het |
| Ccz1 |
A |
T |
5: 143,949,628 (GRCm39) |
M100K |
probably damaging |
Het |
| Cep128 |
T |
C |
12: 91,226,936 (GRCm39) |
T678A |
probably benign |
Het |
| Cep290 |
G |
A |
10: 100,330,773 (GRCm39) |
R151Q |
probably benign |
Het |
| Crip3 |
A |
G |
17: 46,741,673 (GRCm39) |
|
probably benign |
Het |
| Ddx60 |
A |
G |
8: 62,474,348 (GRCm39) |
M1479V |
possibly damaging |
Het |
| Defb40 |
T |
A |
8: 19,025,093 (GRCm39) |
I38F |
probably benign |
Het |
| Dnajb2 |
C |
T |
1: 75,220,198 (GRCm39) |
T221I |
possibly damaging |
Het |
| Dpysl3 |
T |
C |
18: 43,467,079 (GRCm39) |
I279V |
probably damaging |
Het |
| Echs1 |
G |
A |
7: 139,692,499 (GRCm39) |
|
probably benign |
Het |
| Efl1 |
T |
A |
7: 82,320,835 (GRCm39) |
N89K |
probably damaging |
Het |
| Extl3 |
T |
C |
14: 65,313,443 (GRCm39) |
T580A |
probably benign |
Het |
| Fam171a2 |
C |
T |
11: 102,330,982 (GRCm39) |
G193E |
probably damaging |
Het |
| Fam234a |
A |
T |
17: 26,435,591 (GRCm39) |
D264E |
probably benign |
Het |
| Fbxw20 |
A |
T |
9: 109,063,763 (GRCm39) |
V3D |
possibly damaging |
Het |
| Fig4 |
G |
A |
10: 41,109,586 (GRCm39) |
P637L |
probably benign |
Het |
| Fnbp1l |
G |
A |
3: 122,339,964 (GRCm39) |
T496I |
probably benign |
Het |
| Fry |
T |
C |
5: 150,325,108 (GRCm39) |
V1175A |
possibly damaging |
Het |
| Gm5617 |
C |
T |
9: 48,406,968 (GRCm39) |
A34V |
possibly damaging |
Het |
| Gnai1 |
A |
T |
5: 18,496,596 (GRCm39) |
V109E |
probably benign |
Het |
| H2-K2 |
A |
T |
17: 34,216,298 (GRCm39) |
Y283N |
probably benign |
Het |
| Hectd2 |
A |
T |
19: 36,582,682 (GRCm39) |
I471F |
probably damaging |
Het |
| Hsdl2 |
T |
C |
4: 59,612,812 (GRCm39) |
|
probably null |
Het |
| Igkv3-1 |
T |
C |
6: 70,681,028 (GRCm39) |
S76P |
probably damaging |
Het |
| Krt15 |
A |
T |
11: 100,022,897 (GRCm39) |
S439R |
probably benign |
Het |
| Lama2 |
TTTGCGCATT |
TTT |
10: 26,919,639 (GRCm39) |
|
probably null |
Het |
| Lima1 |
G |
A |
15: 99,717,457 (GRCm39) |
T23I |
probably benign |
Het |
| Map4k1 |
C |
A |
7: 28,688,195 (GRCm39) |
H248Q |
probably damaging |
Het |
| Mcf2l |
C |
A |
8: 13,063,972 (GRCm39) |
T1004K |
probably damaging |
Het |
| Meak7 |
T |
G |
8: 120,499,262 (GRCm39) |
T77P |
probably benign |
Het |
| Micall1 |
T |
A |
15: 79,007,146 (GRCm39) |
|
probably benign |
Het |
| Ms4a14 |
A |
G |
19: 11,278,976 (GRCm39) |
I1194T |
probably benign |
Het |
| Mtor |
T |
C |
4: 148,539,273 (GRCm39) |
*257Q |
probably null |
Het |
| Mucl3 |
G |
A |
17: 35,948,468 (GRCm39) |
T377I |
possibly damaging |
Het |
| Ncan |
T |
A |
8: 70,556,705 (GRCm39) |
T961S |
probably benign |
Het |
| Odad4 |
A |
G |
11: 100,441,147 (GRCm39) |
N126S |
probably damaging |
Het |
| Or10z1 |
A |
T |
1: 174,078,262 (GRCm39) |
I77N |
probably damaging |
Het |
| Or1e29 |
T |
A |
11: 73,667,372 (GRCm39) |
L260F |
probably benign |
Het |
| Or1f19 |
T |
C |
16: 3,410,706 (GRCm39) |
S149P |
probably damaging |
Het |
| Or2t49 |
T |
A |
11: 58,392,735 (GRCm39) |
I216F |
probably damaging |
Het |
| Or8h10 |
T |
G |
2: 86,808,693 (GRCm39) |
Y149S |
probably damaging |
Het |
| Or9e1 |
T |
A |
11: 58,732,033 (GRCm39) |
L31H |
possibly damaging |
Het |
| Pcdhgb2 |
A |
G |
18: 37,825,153 (GRCm39) |
R715G |
probably benign |
Het |
| Pik3c3 |
T |
C |
18: 30,477,131 (GRCm39) |
|
probably null |
Het |
| Pkhd1l1 |
A |
T |
15: 44,354,497 (GRCm39) |
D296V |
probably damaging |
Het |
| Plekhh2 |
A |
G |
17: 84,908,125 (GRCm39) |
I1189V |
probably damaging |
Het |
| Psg18 |
A |
T |
7: 18,087,409 (GRCm39) |
L83Q |
possibly damaging |
Het |
| Rps6kc1 |
A |
G |
1: 190,532,515 (GRCm39) |
W496R |
probably damaging |
Het |
| Setd5 |
C |
T |
6: 113,126,527 (GRCm39) |
T1188I |
probably damaging |
Het |
| Slc4a3 |
T |
C |
1: 75,531,729 (GRCm39) |
F899L |
probably damaging |
Het |
| Slitrk6 |
T |
C |
14: 110,989,315 (GRCm39) |
T131A |
probably damaging |
Het |
| Speg |
G |
T |
1: 75,398,379 (GRCm39) |
R1942L |
probably damaging |
Het |
| Sulf2 |
C |
A |
2: 165,923,524 (GRCm39) |
R565L |
probably benign |
Het |
| Tcerg1 |
T |
C |
18: 42,657,046 (GRCm39) |
M176T |
unknown |
Het |
| Tfcp2l1 |
T |
C |
1: 118,597,239 (GRCm39) |
I440T |
possibly damaging |
Het |
| Tgm7 |
A |
T |
2: 120,929,445 (GRCm39) |
|
probably null |
Het |
| Tjp2 |
C |
A |
19: 24,099,484 (GRCm39) |
G433V |
probably damaging |
Het |
| Tmc7 |
C |
T |
7: 118,142,565 (GRCm39) |
G608R |
probably damaging |
Het |
| Tmed4 |
A |
G |
11: 6,224,456 (GRCm39) |
F68S |
possibly damaging |
Het |
| Tmem30b |
G |
A |
12: 73,592,686 (GRCm39) |
P143L |
probably damaging |
Het |
| Tnfrsf23 |
C |
T |
7: 143,235,217 (GRCm39) |
C49Y |
probably damaging |
Het |
| Tnni3k |
A |
T |
3: 154,492,445 (GRCm39) |
|
probably null |
Het |
| Trav12-2 |
G |
T |
14: 53,854,150 (GRCm39) |
M41I |
probably benign |
Het |
| Trim6 |
T |
A |
7: 103,881,692 (GRCm39) |
Y314* |
probably null |
Het |
| Utp25 |
A |
G |
1: 192,796,072 (GRCm39) |
Y686H |
probably damaging |
Het |
| Vmn2r118 |
A |
G |
17: 55,899,894 (GRCm39) |
V670A |
probably damaging |
Het |
| Zfp438 |
A |
T |
18: 5,213,154 (GRCm39) |
D601E |
probably benign |
Het |
| Zfp606 |
T |
A |
7: 12,226,983 (GRCm39) |
I310N |
possibly damaging |
Het |
|
| Other mutations in Ccdc180 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01369:Ccdc180
|
APN |
4 |
45,900,256 (GRCm39) |
missense |
probably benign |
|
|
IGL01713:Ccdc180
|
APN |
4 |
45,921,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01915:Ccdc180
|
APN |
4 |
45,904,544 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01935:Ccdc180
|
APN |
4 |
45,906,889 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL02539:Ccdc180
|
APN |
4 |
45,921,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02982:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03071:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
IGL03146:Ccdc180
|
APN |
4 |
45,903,840 (GRCm39) |
splice site |
probably benign |
|
|
PIT4687001:Ccdc180
|
UTSW |
4 |
45,949,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0049:Ccdc180
|
UTSW |
4 |
45,930,119 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0054:Ccdc180
|
UTSW |
4 |
45,890,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0080:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0082:Ccdc180
|
UTSW |
4 |
45,896,205 (GRCm39) |
missense |
probably null |
0.00 |
|
R0126:Ccdc180
|
UTSW |
4 |
45,912,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0193:Ccdc180
|
UTSW |
4 |
45,914,803 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0276:Ccdc180
|
UTSW |
4 |
45,923,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Ccdc180
|
UTSW |
4 |
45,923,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Ccdc180
|
UTSW |
4 |
45,930,197 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0468:Ccdc180
|
UTSW |
4 |
45,923,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0539:Ccdc180
|
UTSW |
4 |
45,922,010 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0543:Ccdc180
|
UTSW |
4 |
45,900,041 (GRCm39) |
nonsense |
probably null |
|
|
R0546:Ccdc180
|
UTSW |
4 |
45,904,597 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0612:Ccdc180
|
UTSW |
4 |
45,927,969 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0792:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1056:Ccdc180
|
UTSW |
4 |
45,916,375 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1099:Ccdc180
|
UTSW |
4 |
45,914,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1136:Ccdc180
|
UTSW |
4 |
45,914,589 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1263:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1331:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1522:Ccdc180
|
UTSW |
4 |
45,927,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1819:Ccdc180
|
UTSW |
4 |
45,926,195 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R2022:Ccdc180
|
UTSW |
4 |
45,944,418 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2056:Ccdc180
|
UTSW |
4 |
45,932,477 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2219:Ccdc180
|
UTSW |
4 |
45,944,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2228:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2229:Ccdc180
|
UTSW |
4 |
45,948,856 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2255:Ccdc180
|
UTSW |
4 |
45,921,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2427:Ccdc180
|
UTSW |
4 |
45,929,545 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3001:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3002:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3003:Ccdc180
|
UTSW |
4 |
45,899,988 (GRCm39) |
missense |
probably benign |
|
|
R3110:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3111:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3112:Ccdc180
|
UTSW |
4 |
45,900,470 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3898:Ccdc180
|
UTSW |
4 |
45,912,799 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4022:Ccdc180
|
UTSW |
4 |
45,904,560 (GRCm39) |
nonsense |
probably null |
|
|
R4084:Ccdc180
|
UTSW |
4 |
45,950,632 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4377:Ccdc180
|
UTSW |
4 |
45,941,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4595:Ccdc180
|
UTSW |
4 |
45,945,023 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4637:Ccdc180
|
UTSW |
4 |
45,914,443 (GRCm39) |
missense |
probably benign |
|
|
R4811:Ccdc180
|
UTSW |
4 |
45,928,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4825:Ccdc180
|
UTSW |
4 |
45,912,794 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4888:Ccdc180
|
UTSW |
4 |
45,909,308 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Ccdc180
|
UTSW |
4 |
45,917,453 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5042:Ccdc180
|
UTSW |
4 |
45,916,255 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5119:Ccdc180
|
UTSW |
4 |
45,914,603 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5177:Ccdc180
|
UTSW |
4 |
45,917,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5311:Ccdc180
|
UTSW |
4 |
45,917,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5333:Ccdc180
|
UTSW |
4 |
45,890,935 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5448:Ccdc180
|
UTSW |
4 |
45,920,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5510:Ccdc180
|
UTSW |
4 |
45,928,046 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6018:Ccdc180
|
UTSW |
4 |
45,926,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6108:Ccdc180
|
UTSW |
4 |
45,911,389 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6283:Ccdc180
|
UTSW |
4 |
45,902,486 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6483:Ccdc180
|
UTSW |
4 |
45,921,950 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6618:Ccdc180
|
UTSW |
4 |
45,950,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Ccdc180
|
UTSW |
4 |
45,940,934 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7205:Ccdc180
|
UTSW |
4 |
45,914,588 (GRCm39) |
missense |
probably benign |
|
|
R7341:Ccdc180
|
UTSW |
4 |
45,898,644 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7351:Ccdc180
|
UTSW |
4 |
45,903,887 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7418:Ccdc180
|
UTSW |
4 |
45,904,616 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7492:Ccdc180
|
UTSW |
4 |
45,930,009 (GRCm39) |
splice site |
probably null |
|
|
R7573:Ccdc180
|
UTSW |
4 |
45,922,015 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7639:Ccdc180
|
UTSW |
4 |
45,928,043 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7792:Ccdc180
|
UTSW |
4 |
45,890,389 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7806:Ccdc180
|
UTSW |
4 |
45,912,801 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7812:Ccdc180
|
UTSW |
4 |
45,906,952 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7840:Ccdc180
|
UTSW |
4 |
45,900,461 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7842:Ccdc180
|
UTSW |
4 |
45,909,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8712:Ccdc180
|
UTSW |
4 |
45,920,842 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8818:Ccdc180
|
UTSW |
4 |
45,900,484 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8961:Ccdc180
|
UTSW |
4 |
45,929,573 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R8983:Ccdc180
|
UTSW |
4 |
45,909,359 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9035:Ccdc180
|
UTSW |
4 |
45,906,922 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Ccdc180
|
UTSW |
4 |
45,949,466 (GRCm39) |
nonsense |
probably null |
|
|
R9240:Ccdc180
|
UTSW |
4 |
45,917,566 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9293:Ccdc180
|
UTSW |
4 |
45,944,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9328:Ccdc180
|
UTSW |
4 |
45,902,447 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9346:Ccdc180
|
UTSW |
4 |
45,927,953 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9521:Ccdc180
|
UTSW |
4 |
45,916,283 (GRCm39) |
missense |
probably null |
0.50 |
|
R9653:Ccdc180
|
UTSW |
4 |
45,923,495 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9667:Ccdc180
|
UTSW |
4 |
45,920,861 (GRCm39) |
nonsense |
probably null |
|
|
X0017:Ccdc180
|
UTSW |
4 |
45,909,350 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,920,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ccdc180
|
UTSW |
4 |
45,916,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGGGATGTAAAGCCATGG -3'
(R):5'- TCGTTGGCCTGTAAGGAAAAG -3'
Sequencing Primer
(F):5'- CATGGGCCTCGGGATGTG -3'
(R):5'- ACCTAGACCTGGAGTGTTAGAACTTG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation