Incidental Mutation 'R5190:Vmn1r195'
ID398070
Institutional Source Beutler Lab
Gene Symbol Vmn1r195
Ensembl Gene ENSMUSG00000069296
Gene Namevomeronasal 1 receptor 195
SynonymsV1ri6
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.050) question?
Stock #R5190 (G1)
Quality Score225
Status Not validated
Chromosome13
Chromosomal Location22270522-22281230 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) C to T at 22278386 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Stop codon at position 9 (R9*)
Ref Sequence ENSEMBL: ENSMUSP00000154274 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000091736] [ENSMUST00000228711]
Predicted Effect probably null
Transcript: ENSMUST00000091736
AA Change: R9*
SMART Domains Protein: ENSMUSP00000089330
Gene: ENSMUSG00000069296
AA Change: R9*

DomainStartEndE-ValueType
transmembrane domain 10 32 N/A INTRINSIC
Pfam:V1R 34 300 5.6e-41 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000121379
Predicted Effect probably null
Transcript: ENSMUST00000228711
AA Change: R9*
Coding Region Coverage
  • 1x: 99.2%
  • 3x: 98.5%
  • 10x: 96.9%
  • 20x: 94.1%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2700049A03Rik G T 12: 71,164,546 E685* probably null Het
2700049A03Rik A T 12: 71,164,547 E685V possibly damaging Het
Abca7 T C 10: 79,999,593 probably null Het
Abca8a C T 11: 110,089,909 probably null Het
Ablim3 A G 18: 61,819,911 Y361H probably benign Het
Acan C T 7: 79,098,541 T1020I probably benign Het
Baat A G 4: 49,499,652 L218P probably damaging Het
Bcl11b C A 12: 107,989,716 C58F probably damaging Het
Cand2 G T 6: 115,789,513 A360S probably damaging Het
Cdh2 A G 18: 16,650,315 V62A possibly damaging Het
Cep44 C T 8: 56,532,796 V354I probably benign Het
Col3a1 G A 1: 45,329,084 R309Q unknown Het
Col3a1 G A 1: 45,344,807 probably benign Het
Coq5 A G 5: 115,295,780 probably null Het
Crtac1 A G 19: 42,333,908 I131T possibly damaging Het
Decr1 C T 4: 15,924,270 V217M probably damaging Het
Dnajc13 A G 9: 104,174,525 V1706A probably benign Het
Dopey1 A G 9: 86,487,304 I63M probably damaging Het
F830045P16Rik T C 2: 129,472,715 D214G probably benign Het
Fam216a T A 5: 122,367,521 probably null Het
Fdxacb1 A C 9: 50,772,087 H248P possibly damaging Het
Gnai1 A T 5: 18,291,598 V109E probably benign Het
Helz2 A T 2: 181,230,757 probably null Het
Itgam T C 7: 128,116,317 probably null Het
Kcnh1 A G 1: 192,505,528 S766G probably benign Het
Klra1 C A 6: 130,375,278 C167F probably damaging Het
Krtap9-3 T A 11: 99,597,982 T25S probably benign Het
Mapk6 T C 9: 75,388,344 Y624C probably damaging Het
Olfr1123 A G 2: 87,418,843 Y263C probably damaging Het
Olfr1158 T A 2: 87,990,763 Y217* probably null Het
Olfr1393 T C 11: 49,280,382 V78A probably damaging Het
Olfr51 T G 11: 51,007,554 I194S probably damaging Het
Olfr677 C T 7: 105,056,453 S69L probably damaging Het
P3h2 A G 16: 25,984,949 S356P possibly damaging Het
Pde12 C T 14: 26,666,377 probably null Het
Rln3 T G 8: 84,043,237 K94N probably damaging Het
Skint5 T C 4: 113,763,514 I668V unknown Het
Slitrk5 C A 14: 111,679,420 Q159K probably damaging Het
Trim3 G T 7: 105,619,509 N79K probably damaging Het
Tyw1 T A 5: 130,267,915 C101* probably null Het
Ulk2 T C 11: 61,781,711 T934A probably benign Het
Unc5b T C 10: 60,772,293 Y687C probably benign Het
Zfc3h1 T G 10: 115,418,692 L1397R probably damaging Het
Zfp296 T C 7: 19,577,407 V9A probably benign Het
Zfp423 T A 8: 87,782,463 S397C probably damaging Het
Other mutations in Vmn1r195
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01751:Vmn1r195 APN 13 22279251 missense probably benign 0.45
IGL01752:Vmn1r195 APN 13 22279251 missense probably benign 0.45
IGL01780:Vmn1r195 APN 13 22279085 missense probably benign 0.34
PIT4812001:Vmn1r195 UTSW 13 22278863 missense probably benign 0.22
R0066:Vmn1r195 UTSW 13 22279239 missense possibly damaging 0.94
R0066:Vmn1r195 UTSW 13 22279239 missense possibly damaging 0.94
R0350:Vmn1r195 UTSW 13 22279233 missense probably damaging 0.99
R0639:Vmn1r195 UTSW 13 22278941 missense probably damaging 1.00
R0751:Vmn1r195 UTSW 13 22279011 missense probably damaging 1.00
R1184:Vmn1r195 UTSW 13 22279011 missense probably damaging 1.00
R1464:Vmn1r195 UTSW 13 22279178 missense probably benign 0.01
R1464:Vmn1r195 UTSW 13 22279178 missense probably benign 0.01
R1999:Vmn1r195 UTSW 13 22278764 missense possibly damaging 0.83
R2150:Vmn1r195 UTSW 13 22278764 missense possibly damaging 0.83
R4924:Vmn1r195 UTSW 13 22279019 missense probably benign 0.03
R5522:Vmn1r195 UTSW 13 22278950 missense probably damaging 1.00
R5621:Vmn1r195 UTSW 13 22278389 missense probably benign 0.01
R6509:Vmn1r195 UTSW 13 22279109 missense probably benign 0.45
R7288:Vmn1r195 UTSW 13 22279004 missense probably damaging 1.00
R7291:Vmn1r195 UTSW 13 22278749 missense probably damaging 1.00
R7428:Vmn1r195 UTSW 13 22278852 missense probably benign 0.01
R7810:Vmn1r195 UTSW 13 22279074 missense probably damaging 1.00
Predicted Primers PCR Primer
(F):5'- AGCAAAGAATTCAATCAGGTGCATG -3'
(R):5'- TTTTACAGCCTGCAATGCCCAG -3'

Sequencing Primer
(F):5'- GTGCATGCTGTAAAAGAACCATGTAC -3'
(R):5'- GTGGCTACATATCTGATCCCCGAAG -3'
Posted On2016-07-06