Incidental Mutation 'R0755:Disp2'
| ID |
70391 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Disp2
|
| Ensembl Gene |
ENSMUSG00000040035 |
| Gene Name |
dispatched RND transporter family member 2 |
| Synonyms |
B230210L08Rik, DispB |
| MMRRC Submission |
038935-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.896)
|
| Stock # |
R0755 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
118610183-118625656 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 118620243 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Serine
at position 325
(F325S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037136
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000037547]
[ENSMUST00000063975]
[ENSMUST00000110843]
[ENSMUST00000110846]
|
| AlphaFold |
Q8CIP5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000037547
AA Change: F325S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000037136
Gene: ENSMUSG00000040035
AA Change: F325S
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
Pfam:MMPL
|
435 |
635 |
9.7e-8 |
PFAM |
|
Pfam:Sterol-sensing
|
458 |
611 |
9.1e-9 |
PFAM |
|
transmembrane domain
|
657 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
682 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
761 |
N/A |
INTRINSIC |
|
transmembrane domain
|
914 |
936 |
N/A |
INTRINSIC |
|
transmembrane domain
|
943 |
965 |
N/A |
INTRINSIC |
|
transmembrane domain
|
975 |
997 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1018 |
1040 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063975
|
| SMART Domains |
Protein: ENSMUSP00000070031
Gene: ENSMUSG00000040035
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110843
|
| SMART Domains |
Protein: ENSMUSP00000106467
Gene: ENSMUSG00000040035
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110846
|
| SMART Domains |
Protein: ENSMUSP00000106470
Gene: ENSMUSG00000040035
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
123 |
145 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
203 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142072
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. [provided by RefSeq, Sep 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730061H03Rik |
A |
T |
14: 55,797,638 (GRCm39) |
|
probably benign |
Het |
| Acin1 |
A |
G |
14: 54,889,292 (GRCm39) |
M1T |
probably null |
Het |
| Akp3 |
G |
A |
1: 87,055,593 (GRCm39) |
G547R |
unknown |
Het |
| Aldh1a1 |
A |
G |
19: 20,595,358 (GRCm39) |
M96V |
probably benign |
Het |
| Ankfn1 |
T |
A |
11: 89,282,913 (GRCm39) |
M245L |
probably benign |
Het |
| Arhgap19 |
T |
C |
19: 41,769,614 (GRCm39) |
K54E |
probably damaging |
Het |
| Atp1a2 |
T |
C |
1: 172,116,948 (GRCm39) |
Q223R |
probably benign |
Het |
| Atp8a2 |
C |
T |
14: 60,247,330 (GRCm39) |
V557I |
possibly damaging |
Het |
| AU041133 |
A |
T |
10: 81,986,724 (GRCm39) |
K126* |
probably null |
Het |
| Axin1 |
T |
A |
17: 26,401,480 (GRCm39) |
Y351N |
possibly damaging |
Het |
| Baiap2l1 |
T |
C |
5: 144,221,367 (GRCm39) |
K176E |
probably damaging |
Het |
| Baz2a |
C |
T |
10: 127,955,560 (GRCm39) |
T848I |
possibly damaging |
Het |
| Bbs2 |
A |
C |
8: 94,808,708 (GRCm39) |
V333G |
probably benign |
Het |
| BC051019 |
G |
A |
7: 109,315,302 (GRCm39) |
Q318* |
probably null |
Het |
| Bltp1 |
T |
C |
3: 37,000,513 (GRCm39) |
S1231P |
probably damaging |
Het |
| Cdc37 |
C |
T |
9: 21,051,160 (GRCm39) |
D362N |
probably damaging |
Het |
| Cep170 |
A |
T |
1: 176,583,319 (GRCm39) |
V1020E |
probably damaging |
Het |
| Chrm4 |
T |
C |
2: 91,758,747 (GRCm39) |
V385A |
probably benign |
Het |
| Cntrl |
G |
A |
2: 35,035,151 (GRCm39) |
S373N |
probably damaging |
Het |
| Col23a1 |
G |
A |
11: 51,467,706 (GRCm39) |
G19D |
probably damaging |
Het |
| Cyb5r4 |
G |
T |
9: 86,911,625 (GRCm39) |
A100S |
probably damaging |
Het |
| Dctn1 |
C |
T |
6: 83,166,059 (GRCm39) |
P115S |
probably damaging |
Het |
| Dhrs2 |
C |
T |
14: 55,472,247 (GRCm39) |
T46M |
probably damaging |
Het |
| Dnah11 |
T |
G |
12: 117,918,564 (GRCm39) |
T3456P |
possibly damaging |
Het |
| Dnah11 |
C |
A |
12: 118,162,360 (GRCm39) |
V70F |
probably benign |
Het |
| Duoxa1 |
T |
A |
2: 122,135,161 (GRCm39) |
T195S |
probably benign |
Het |
| Dync2i1 |
T |
C |
12: 116,175,412 (GRCm39) |
I922V |
probably benign |
Het |
| Eif2ak1 |
T |
A |
5: 143,821,742 (GRCm39) |
F353I |
possibly damaging |
Het |
| Esam |
A |
G |
9: 37,447,998 (GRCm39) |
T211A |
probably damaging |
Het |
| Faf1 |
A |
G |
4: 109,819,036 (GRCm39) |
N636S |
probably benign |
Het |
| Fbxo25 |
A |
G |
8: 13,985,219 (GRCm39) |
Y305C |
probably benign |
Het |
| Fchsd1 |
C |
T |
18: 38,101,803 (GRCm39) |
|
probably null |
Het |
| Fdxacb1 |
T |
A |
9: 50,683,025 (GRCm39) |
D329E |
possibly damaging |
Het |
| Gvin2 |
A |
T |
7: 105,545,892 (GRCm39) |
F2387I |
possibly damaging |
Het |
| Hbq1b |
A |
T |
11: 32,237,104 (GRCm39) |
|
probably null |
Het |
| Hmcn2 |
T |
A |
2: 31,343,172 (GRCm39) |
V4566E |
probably damaging |
Het |
| Igkv6-29 |
G |
A |
6: 70,116,053 (GRCm39) |
T5I |
probably benign |
Het |
| Itfg1 |
A |
T |
8: 86,452,834 (GRCm39) |
D511E |
possibly damaging |
Het |
| Jmjd1c |
C |
T |
10: 66,932,378 (GRCm39) |
|
probably benign |
Het |
| Kat6b |
T |
A |
14: 21,687,661 (GRCm39) |
M570K |
probably damaging |
Het |
| Kdm4d |
T |
A |
9: 14,375,591 (GRCm39) |
K89M |
probably damaging |
Het |
| Krt19 |
A |
T |
11: 100,032,965 (GRCm39) |
D194E |
possibly damaging |
Het |
| Lamc1 |
A |
T |
1: 153,123,196 (GRCm39) |
Y665N |
possibly damaging |
Het |
| Lct |
A |
T |
1: 128,221,872 (GRCm39) |
S1556T |
possibly damaging |
Het |
| Macf1 |
A |
G |
4: 123,263,719 (GRCm39) |
L4924P |
probably damaging |
Het |
| Mef2c |
G |
A |
13: 83,804,472 (GRCm39) |
|
probably null |
Het |
| Mff |
G |
A |
1: 82,728,326 (GRCm39) |
|
probably null |
Het |
| Mycbp2 |
A |
T |
14: 103,412,230 (GRCm39) |
L2581Q |
probably damaging |
Het |
| Mylk |
G |
C |
16: 34,699,845 (GRCm39) |
E403Q |
possibly damaging |
Het |
| Nos3 |
T |
A |
5: 24,572,295 (GRCm39) |
L123M |
probably damaging |
Het |
| Ntn5 |
C |
T |
7: 45,335,952 (GRCm39) |
P128S |
probably benign |
Het |
| Nudt9 |
T |
C |
5: 104,212,920 (GRCm39) |
V331A |
probably damaging |
Het |
| Or2y3 |
A |
T |
17: 38,393,085 (GRCm39) |
Y261* |
probably null |
Het |
| Or7g34 |
T |
C |
9: 19,478,415 (GRCm39) |
I88M |
possibly damaging |
Het |
| Pcdh7 |
A |
T |
5: 57,877,664 (GRCm39) |
K406N |
possibly damaging |
Het |
| Pkdrej |
T |
A |
15: 85,700,336 (GRCm39) |
I1867L |
probably benign |
Het |
| Plppr4 |
C |
T |
3: 117,116,319 (GRCm39) |
G455R |
possibly damaging |
Het |
| Pramel11 |
A |
G |
4: 143,624,299 (GRCm39) |
V66A |
probably damaging |
Het |
| Prkag2 |
G |
C |
5: 25,152,629 (GRCm39) |
S158R |
probably benign |
Het |
| Ptprq |
T |
G |
10: 107,418,400 (GRCm39) |
T1659P |
probably benign |
Het |
| Rasl12 |
A |
G |
9: 65,318,241 (GRCm39) |
K202E |
probably benign |
Het |
| Rb1 |
A |
C |
14: 73,434,653 (GRCm39) |
*922G |
probably null |
Het |
| Rsf1 |
C |
T |
7: 97,229,174 (GRCm39) |
P22S |
probably damaging |
Het |
| Scn1a |
T |
G |
2: 66,151,379 (GRCm39) |
T797P |
probably damaging |
Het |
| Sgsm2 |
A |
G |
11: 74,756,323 (GRCm39) |
V342A |
probably damaging |
Het |
| Slc22a7 |
T |
G |
17: 46,749,113 (GRCm39) |
H68P |
possibly damaging |
Het |
| Slc4a2 |
G |
A |
5: 24,640,575 (GRCm39) |
A652T |
probably benign |
Het |
| Slc5a1 |
T |
A |
5: 33,290,733 (GRCm39) |
L106M |
probably benign |
Het |
| Slco1c1 |
C |
T |
6: 141,477,258 (GRCm39) |
P19S |
probably damaging |
Het |
| Snx1 |
A |
G |
9: 66,005,738 (GRCm39) |
F127S |
probably damaging |
Het |
| Snx31 |
A |
T |
15: 36,534,576 (GRCm39) |
I199N |
probably damaging |
Het |
| Snx33 |
T |
C |
9: 56,832,741 (GRCm39) |
I443V |
possibly damaging |
Het |
| Sptbn1 |
A |
G |
11: 30,089,016 (GRCm39) |
F749L |
probably damaging |
Het |
| Stoml3 |
T |
A |
3: 53,405,559 (GRCm39) |
Y53* |
probably null |
Het |
| Stxbp2 |
A |
G |
8: 3,692,019 (GRCm39) |
T554A |
probably benign |
Het |
| Tal1 |
T |
C |
4: 114,925,573 (GRCm39) |
I214T |
probably damaging |
Het |
| Tas2r140 |
T |
A |
6: 40,468,344 (GRCm39) |
I58N |
probably damaging |
Het |
| Thap1 |
A |
G |
8: 26,648,501 (GRCm39) |
Y8C |
probably damaging |
Het |
| Thsd7a |
A |
T |
6: 12,555,368 (GRCm39) |
L172Q |
probably damaging |
Het |
| Ube3c |
T |
A |
5: 29,842,740 (GRCm39) |
D735E |
probably damaging |
Het |
| Unc80 |
G |
A |
1: 66,544,082 (GRCm39) |
D402N |
probably damaging |
Het |
| Upf1 |
G |
T |
8: 70,786,779 (GRCm39) |
R902S |
probably benign |
Het |
| Urb1 |
A |
G |
16: 90,570,982 (GRCm39) |
Y1276H |
probably damaging |
Het |
| Urb1 |
A |
T |
16: 90,576,026 (GRCm39) |
F843L |
probably benign |
Het |
| Vmn1r198 |
C |
T |
13: 22,539,402 (GRCm39) |
T296I |
probably benign |
Het |
| Vmn1r33 |
A |
T |
6: 66,588,892 (GRCm39) |
S221T |
probably damaging |
Het |
| Vmn2r103 |
A |
G |
17: 19,993,830 (GRCm39) |
D69G |
probably benign |
Het |
| Vmn2r14 |
T |
G |
5: 109,364,226 (GRCm39) |
L563F |
possibly damaging |
Het |
| Vmn2r60 |
G |
A |
7: 41,844,869 (GRCm39) |
G744D |
probably damaging |
Het |
| Vstm4 |
T |
C |
14: 32,614,601 (GRCm39) |
V181A |
probably damaging |
Het |
| Wdr72 |
G |
A |
9: 74,052,376 (GRCm39) |
V136I |
probably benign |
Het |
| Zfp236 |
T |
A |
18: 82,638,457 (GRCm39) |
N1388Y |
probably damaging |
Het |
| Zfp53 |
T |
A |
17: 21,728,839 (GRCm39) |
F291I |
probably damaging |
Het |
| Zfp944 |
A |
T |
17: 22,558,889 (GRCm39) |
H119Q |
possibly damaging |
Het |
|
| Other mutations in Disp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Disp2
|
APN |
2 |
118,616,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00970:Disp2
|
APN |
2 |
118,622,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01790:Disp2
|
APN |
2 |
118,621,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01809:Disp2
|
APN |
2 |
118,617,745 (GRCm39) |
splice site |
probably benign |
|
|
IGL02069:Disp2
|
APN |
2 |
118,621,161 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02140:Disp2
|
APN |
2 |
118,621,350 (GRCm39) |
missense |
probably benign |
|
|
IGL02143:Disp2
|
APN |
2 |
118,620,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02155:Disp2
|
APN |
2 |
118,622,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02884:Disp2
|
APN |
2 |
118,618,032 (GRCm39) |
splice site |
probably benign |
|
|
IGL03113:Disp2
|
APN |
2 |
118,621,259 (GRCm39) |
splice site |
probably null |
|
|
IGL03194:Disp2
|
APN |
2 |
118,618,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4453001:Disp2
|
UTSW |
2 |
118,618,125 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0109:Disp2
|
UTSW |
2 |
118,622,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0126:Disp2
|
UTSW |
2 |
118,620,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0603:Disp2
|
UTSW |
2 |
118,622,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0610:Disp2
|
UTSW |
2 |
118,622,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0639:Disp2
|
UTSW |
2 |
118,621,325 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0673:Disp2
|
UTSW |
2 |
118,621,325 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0781:Disp2
|
UTSW |
2 |
118,620,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1110:Disp2
|
UTSW |
2 |
118,620,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Disp2
|
UTSW |
2 |
118,636,899 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1148:Disp2
|
UTSW |
2 |
118,636,899 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1243:Disp2
|
UTSW |
2 |
118,622,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1587:Disp2
|
UTSW |
2 |
118,622,064 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1739:Disp2
|
UTSW |
2 |
118,622,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Disp2
|
UTSW |
2 |
118,621,778 (GRCm39) |
nonsense |
probably null |
|
|
R1781:Disp2
|
UTSW |
2 |
118,623,042 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1918:Disp2
|
UTSW |
2 |
118,622,408 (GRCm39) |
missense |
probably benign |
|
|
R1956:Disp2
|
UTSW |
2 |
118,622,704 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2167:Disp2
|
UTSW |
2 |
118,622,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2206:Disp2
|
UTSW |
2 |
118,622,725 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4031:Disp2
|
UTSW |
2 |
118,622,361 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4617:Disp2
|
UTSW |
2 |
118,620,643 (GRCm39) |
missense |
probably benign |
|
|
R4656:Disp2
|
UTSW |
2 |
118,621,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4684:Disp2
|
UTSW |
2 |
118,623,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Disp2
|
UTSW |
2 |
118,622,165 (GRCm39) |
nonsense |
probably null |
|
|
R4697:Disp2
|
UTSW |
2 |
118,622,165 (GRCm39) |
nonsense |
probably null |
|
|
R4738:Disp2
|
UTSW |
2 |
118,620,807 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4834:Disp2
|
UTSW |
2 |
118,622,985 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4914:Disp2
|
UTSW |
2 |
118,620,935 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4915:Disp2
|
UTSW |
2 |
118,620,935 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4918:Disp2
|
UTSW |
2 |
118,620,935 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5045:Disp2
|
UTSW |
2 |
118,622,543 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5208:Disp2
|
UTSW |
2 |
118,622,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5303:Disp2
|
UTSW |
2 |
118,641,329 (GRCm39) |
unclassified |
probably benign |
|
|
R5350:Disp2
|
UTSW |
2 |
118,618,056 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5355:Disp2
|
UTSW |
2 |
118,617,392 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6011:Disp2
|
UTSW |
2 |
118,621,301 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6031:Disp2
|
UTSW |
2 |
118,620,275 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6031:Disp2
|
UTSW |
2 |
118,620,275 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6139:Disp2
|
UTSW |
2 |
118,621,143 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6169:Disp2
|
UTSW |
2 |
118,622,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6187:Disp2
|
UTSW |
2 |
118,622,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Disp2
|
UTSW |
2 |
118,617,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6250:Disp2
|
UTSW |
2 |
118,621,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6392:Disp2
|
UTSW |
2 |
118,621,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7138:Disp2
|
UTSW |
2 |
118,617,361 (GRCm39) |
missense |
probably benign |
|
|
R7156:Disp2
|
UTSW |
2 |
118,622,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7230:Disp2
|
UTSW |
2 |
118,622,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7400:Disp2
|
UTSW |
2 |
118,622,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7460:Disp2
|
UTSW |
2 |
118,620,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7505:Disp2
|
UTSW |
2 |
118,621,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7542:Disp2
|
UTSW |
2 |
118,621,599 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7728:Disp2
|
UTSW |
2 |
118,621,961 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7757:Disp2
|
UTSW |
2 |
118,621,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7798:Disp2
|
UTSW |
2 |
118,622,360 (GRCm39) |
missense |
probably benign |
|
|
R7945:Disp2
|
UTSW |
2 |
118,623,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8013:Disp2
|
UTSW |
2 |
118,620,163 (GRCm39) |
nonsense |
probably null |
|
|
R8085:Disp2
|
UTSW |
2 |
118,617,452 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8179:Disp2
|
UTSW |
2 |
118,623,030 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8288:Disp2
|
UTSW |
2 |
118,620,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8345:Disp2
|
UTSW |
2 |
118,641,284 (GRCm39) |
missense |
unknown |
|
|
R8385:Disp2
|
UTSW |
2 |
118,620,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8700:Disp2
|
UTSW |
2 |
118,620,340 (GRCm39) |
nonsense |
probably null |
|
|
R8808:Disp2
|
UTSW |
2 |
118,620,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8880:Disp2
|
UTSW |
2 |
118,621,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8997:Disp2
|
UTSW |
2 |
118,617,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9022:Disp2
|
UTSW |
2 |
118,621,179 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9181:Disp2
|
UTSW |
2 |
118,617,393 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9660:Disp2
|
UTSW |
2 |
118,620,627 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Disp2
|
UTSW |
2 |
118,621,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Disp2
|
UTSW |
2 |
118,620,183 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTTCAGCATGACAAGAGGTGAGAG -3'
(R):5'- GCACCCCTAGAAGTGACATGAACG -3'
Sequencing Primer
(F):5'- CAGGGTTAAGGTAACCTGGGC -3'
(R):5'- TCGGCTAGGTAATACTTCAGCAG -3'
|
| Posted On |
2013-09-30 |
Incidental Mutation