Incidental Mutation 'R9751:Igflr1'
| ID |
732514 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Igflr1
|
| Ensembl Gene |
ENSMUSG00000036826 |
| Gene Name |
IGF-like family receptor 1 |
| Synonyms |
F630003I17Rik, Tmem149 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9751 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
30264852-30267387 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 30266653 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Leucine
at position 167
(Q167L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132400
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000006470]
[ENSMUST00000043273]
[ENSMUST00000043850]
[ENSMUST00000043898]
[ENSMUST00000108154]
[ENSMUST00000108161]
[ENSMUST00000163276]
[ENSMUST00000163330]
[ENSMUST00000163464]
[ENSMUST00000163482]
[ENSMUST00000163654]
[ENSMUST00000163848]
[ENSMUST00000164365]
[ENSMUST00000166257]
[ENSMUST00000166510]
[ENSMUST00000166960]
[ENSMUST00000167042]
[ENSMUST00000167202]
[ENSMUST00000167361]
[ENSMUST00000172251]
[ENSMUST00000167501]
[ENSMUST00000168229]
[ENSMUST00000168333]
[ENSMUST00000168555]
[ENSMUST00000168931]
[ENSMUST00000171850]
[ENSMUST00000171912]
[ENSMUST00000207031]
[ENSMUST00000207747]
[ENSMUST00000207797]
[ENSMUST00000208628]
|
| AlphaFold |
Q3U4N7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000006470
|
| SMART Domains |
Protein: ENSMUSP00000006470
Gene: ENSMUSG00000006307
| Domain | Start | End | E-Value | Type |
|---|
|
AT_hook
|
18 |
30 |
2.82e2 |
SMART |
|
low complexity region
|
66 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
122 |
N/A |
INTRINSIC |
|
AT_hook
|
149 |
159 |
2.4e2 |
SMART |
|
AT_hook
|
218 |
230 |
1.95e2 |
SMART |
|
low complexity region
|
249 |
263 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
302 |
N/A |
INTRINSIC |
|
coiled coil region
|
353 |
413 |
N/A |
INTRINSIC |
|
AT_hook
|
476 |
488 |
5.47e-1 |
SMART |
|
low complexity region
|
501 |
517 |
N/A |
INTRINSIC |
|
low complexity region
|
578 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
657 |
N/A |
INTRINSIC |
|
low complexity region
|
673 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
715 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
777 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
922 |
N/A |
INTRINSIC |
|
Pfam:zf-CXXC
|
963 |
1010 |
7.2e-15 |
PFAM |
|
low complexity region
|
1039 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1115 |
N/A |
INTRINSIC |
|
PHD
|
1209 |
1256 |
1.25e-5 |
SMART |
|
PHD
|
1257 |
1307 |
5.4e-10 |
SMART |
|
PHD
|
1343 |
1400 |
1.27e-6 |
SMART |
|
low complexity region
|
1415 |
1427 |
N/A |
INTRINSIC |
|
PHD
|
1646 |
1692 |
3.82e-1 |
SMART |
|
FYRN
|
1745 |
1788 |
3.25e-19 |
SMART |
|
low complexity region
|
1881 |
1899 |
N/A |
INTRINSIC |
|
low complexity region
|
1912 |
1942 |
N/A |
INTRINSIC |
|
low complexity region
|
1961 |
1978 |
N/A |
INTRINSIC |
|
low complexity region
|
1991 |
2003 |
N/A |
INTRINSIC |
|
low complexity region
|
2013 |
2026 |
N/A |
INTRINSIC |
|
low complexity region
|
2048 |
2061 |
N/A |
INTRINSIC |
|
low complexity region
|
2087 |
2105 |
N/A |
INTRINSIC |
|
low complexity region
|
2127 |
2138 |
N/A |
INTRINSIC |
|
low complexity region
|
2215 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2239 |
2270 |
N/A |
INTRINSIC |
|
low complexity region
|
2396 |
2406 |
N/A |
INTRINSIC |
|
FYRC
|
2419 |
2504 |
4.83e-36 |
SMART |
|
SET
|
2581 |
2703 |
1.67e-42 |
SMART |
|
PostSET
|
2705 |
2721 |
4.65e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043273
|
| SMART Domains |
Protein: ENSMUSP00000039406
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
RRM
|
66 |
143 |
5.99e-4 |
SMART |
|
ZnF_C3H1
|
149 |
175 |
2.49e-1 |
SMART |
|
low complexity region
|
187 |
219 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000043850
AA Change: Q147L
PolyPhen 2
Score 0.462 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000042312
Gene: ENSMUSG00000036826
AA Change: Q147L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
transmembrane domain
|
166 |
188 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
264 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043898
|
| SMART Domains |
Protein: ENSMUSP00000044682
Gene: ENSMUSG00000036835
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PEN-2
|
7 |
99 |
2.9e-43 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108154
|
| SMART Domains |
Protein: ENSMUSP00000103789
Gene: ENSMUSG00000006307
| Domain | Start | End | E-Value | Type |
|---|
|
AT_hook
|
18 |
30 |
2.82e2 |
SMART |
|
low complexity region
|
66 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
122 |
N/A |
INTRINSIC |
|
AT_hook
|
149 |
159 |
2.4e2 |
SMART |
|
AT_hook
|
218 |
230 |
1.95e2 |
SMART |
|
low complexity region
|
249 |
263 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
302 |
N/A |
INTRINSIC |
|
coiled coil region
|
353 |
413 |
N/A |
INTRINSIC |
|
AT_hook
|
476 |
488 |
5.47e-1 |
SMART |
|
low complexity region
|
501 |
517 |
N/A |
INTRINSIC |
|
low complexity region
|
578 |
606 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
657 |
N/A |
INTRINSIC |
|
low complexity region
|
673 |
700 |
N/A |
INTRINSIC |
|
low complexity region
|
715 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
777 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
922 |
N/A |
INTRINSIC |
|
Pfam:zf-CXXC
|
963 |
1010 |
1e-14 |
PFAM |
|
low complexity region
|
1039 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1115 |
N/A |
INTRINSIC |
|
PHD
|
1209 |
1256 |
1.25e-5 |
SMART |
|
PHD
|
1257 |
1307 |
5.4e-10 |
SMART |
|
PHD
|
1343 |
1400 |
1.27e-6 |
SMART |
|
low complexity region
|
1415 |
1427 |
N/A |
INTRINSIC |
|
PHD
|
1646 |
1692 |
3.82e-1 |
SMART |
|
FYRN
|
1745 |
1788 |
3.25e-19 |
SMART |
|
low complexity region
|
1872 |
1890 |
N/A |
INTRINSIC |
|
low complexity region
|
1903 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1952 |
1969 |
N/A |
INTRINSIC |
|
low complexity region
|
1982 |
1994 |
N/A |
INTRINSIC |
|
low complexity region
|
2004 |
2017 |
N/A |
INTRINSIC |
|
low complexity region
|
2039 |
2052 |
N/A |
INTRINSIC |
|
low complexity region
|
2078 |
2096 |
N/A |
INTRINSIC |
|
low complexity region
|
2118 |
2129 |
N/A |
INTRINSIC |
|
low complexity region
|
2206 |
2226 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2261 |
N/A |
INTRINSIC |
|
low complexity region
|
2383 |
2398 |
N/A |
INTRINSIC |
|
FYRC
|
2411 |
2496 |
4.83e-36 |
SMART |
|
SET
|
2573 |
2695 |
1.67e-42 |
SMART |
|
PostSET
|
2697 |
2713 |
4.65e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108161
|
| SMART Domains |
Protein: ENSMUSP00000103796
Gene: ENSMUSG00000109378
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-CCCH
|
13 |
39 |
8.8e-10 |
PFAM |
|
SCOP:d1jmta_
|
43 |
115 |
2e-17 |
SMART |
|
PDB:1JMT|A
|
43 |
116 |
3e-40 |
PDB |
|
Blast:RRM
|
45 |
116 |
2e-36 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131002
|
| SMART Domains |
Protein: ENSMUSP00000118486
Gene: ENSMUSG00000006307
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
202 |
214 |
N/A |
INTRINSIC |
|
Pfam:zf-CXXC
|
255 |
302 |
5.2e-15 |
PFAM |
|
low complexity region
|
331 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
395 |
407 |
N/A |
INTRINSIC |
|
PHD
|
501 |
548 |
1.25e-5 |
SMART |
|
PHD
|
549 |
599 |
5.4e-10 |
SMART |
|
PHD
|
635 |
692 |
1.27e-6 |
SMART |
|
low complexity region
|
707 |
719 |
N/A |
INTRINSIC |
|
PHD
|
938 |
984 |
3.82e-1 |
SMART |
|
FYRN
|
1037 |
1080 |
3.25e-19 |
SMART |
|
low complexity region
|
1173 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1204 |
1234 |
N/A |
INTRINSIC |
|
low complexity region
|
1253 |
1270 |
N/A |
INTRINSIC |
|
low complexity region
|
1283 |
1295 |
N/A |
INTRINSIC |
|
low complexity region
|
1305 |
1318 |
N/A |
INTRINSIC |
|
low complexity region
|
1340 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1379 |
1397 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1430 |
N/A |
INTRINSIC |
|
low complexity region
|
1507 |
1527 |
N/A |
INTRINSIC |
|
low complexity region
|
1531 |
1562 |
N/A |
INTRINSIC |
|
low complexity region
|
1684 |
1699 |
N/A |
INTRINSIC |
|
FYRC
|
1712 |
1797 |
4.83e-36 |
SMART |
|
SET
|
1874 |
1996 |
1.67e-42 |
SMART |
|
PostSET
|
1998 |
2014 |
4.65e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163276
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163330
|
| SMART Domains |
Protein: ENSMUSP00000129385
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
RRM
|
39 |
116 |
5.99e-4 |
SMART |
|
Pfam:zf-CCCH
|
122 |
148 |
4.9e-8 |
PFAM |
|
low complexity region
|
160 |
192 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163464
|
| SMART Domains |
Protein: ENSMUSP00000125959
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
RRM
|
66 |
143 |
5.99e-4 |
SMART |
|
ZnF_C3H1
|
149 |
171 |
3.95e1 |
SMART |
|
low complexity region
|
183 |
215 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163482
|
| SMART Domains |
Protein: ENSMUSP00000130649
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
54 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163654
|
| SMART Domains |
Protein: ENSMUSP00000131048
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-CCCH
|
13 |
39 |
1.3e-9 |
PFAM |
|
RRM
|
66 |
143 |
5.99e-4 |
SMART |
|
low complexity region
|
167 |
187 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163848
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164365
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165722
|
| SMART Domains |
Protein: ENSMUSP00000125790
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-CCCH
|
1 |
26 |
4.7e-10 |
PFAM |
|
PDB:1JMT|A
|
30 |
51 |
2e-6 |
PDB |
|
SCOP:d1jmta_
|
30 |
51 |
5e-3 |
SMART |
|
Blast:RRM
|
32 |
53 |
7e-8 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166257
|
| SMART Domains |
Protein: ENSMUSP00000125838
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
RRM
|
33 |
104 |
2.35e-2 |
SMART |
|
ZnF_C3H1
|
110 |
136 |
2.49e-1 |
SMART |
|
low complexity region
|
148 |
180 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166510
|
| SMART Domains |
Protein: ENSMUSP00000132316
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
RRM
|
45 |
133 |
2.51e-6 |
SMART |
|
ZnF_C3H1
|
139 |
165 |
2.49e-1 |
SMART |
|
low complexity region
|
177 |
209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166960
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167042
|
| SMART Domains |
Protein: ENSMUSP00000128886
Gene: ENSMUSG00000109378
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
RRM
|
66 |
143 |
5.99e-4 |
SMART |
|
ZnF_C3H1
|
149 |
175 |
2.49e-1 |
SMART |
|
low complexity region
|
187 |
219 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167202
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167361
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000172251
AA Change: Q167L
PolyPhen 2
Score 0.462 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000132400
Gene: ENSMUSG00000036826
AA Change: Q167L
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
41 |
N/A |
INTRINSIC |
|
transmembrane domain
|
186 |
208 |
N/A |
INTRINSIC |
|
low complexity region
|
267 |
284 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167501
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168229
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168333
|
| SMART Domains |
Protein: ENSMUSP00000128950
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:zf-CCCH
|
13 |
39 |
4.8e-10 |
PFAM |
|
PDB:1JMT|A
|
43 |
94 |
5e-21 |
PDB |
|
SCOP:d1jmta_
|
43 |
94 |
2e-9 |
SMART |
|
Blast:RRM
|
45 |
94 |
5e-17 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168555
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168931
|
| SMART Domains |
Protein: ENSMUSP00000129697
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
RRM
|
44 |
119 |
4.14e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171850
|
| SMART Domains |
Protein: ENSMUSP00000131781
Gene: ENSMUSG00000078765
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
PDB:1JMT|A
|
43 |
113 |
1e-16 |
PDB |
|
SCOP:d1jmta_
|
43 |
113 |
1e-9 |
SMART |
|
Blast:RRM
|
45 |
110 |
3e-17 |
BLAST |
|
ZnF_C3H1
|
116 |
142 |
2.49e-1 |
SMART |
|
low complexity region
|
154 |
186 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000171912
|
| SMART Domains |
Protein: ENSMUSP00000130983
Gene: ENSMUSG00000109378
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C3H1
|
13 |
39 |
4.79e-3 |
SMART |
|
RRM
|
66 |
143 |
5.99e-4 |
SMART |
|
ZnF_C3H1
|
149 |
175 |
2.49e-1 |
SMART |
|
low complexity region
|
187 |
219 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207031
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207747
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000207797
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000208628
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.8%
- 10x: 99.5%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 52 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca4 |
A |
G |
3: 121,881,126 (GRCm39) |
N514D |
probably benign |
Het |
| Adgre1 |
G |
A |
17: 57,757,101 (GRCm39) |
R786H |
probably null |
Het |
| Ankrd7 |
G |
A |
6: 18,868,024 (GRCm39) |
V97I |
probably damaging |
Het |
| Bltp1 |
A |
G |
3: 37,065,889 (GRCm39) |
I54M |
|
Het |
| Bmper |
C |
T |
9: 23,318,009 (GRCm39) |
P543S |
possibly damaging |
Het |
| Brwd1 |
A |
T |
16: 95,795,015 (GRCm39) |
M2233K |
possibly damaging |
Het |
| C1s2 |
G |
T |
6: 124,602,553 (GRCm39) |
P553T |
probably damaging |
Het |
| Cachd1 |
G |
A |
4: 100,823,438 (GRCm39) |
V497I |
possibly damaging |
Het |
| Cacng4 |
A |
G |
11: 107,626,019 (GRCm39) |
S191P |
probably damaging |
Het |
| Cd109 |
C |
A |
9: 78,605,442 (GRCm39) |
T1015K |
probably damaging |
Het |
| Clstn2 |
A |
G |
9: 97,339,703 (GRCm39) |
L756P |
probably damaging |
Het |
| Crybg3 |
A |
T |
16: 59,377,887 (GRCm39) |
D1122E |
possibly damaging |
Het |
| Csf2 |
A |
T |
11: 54,140,420 (GRCm39) |
L6* |
probably null |
Het |
| Csnk1g2 |
T |
A |
10: 80,473,745 (GRCm39) |
Y71N |
possibly damaging |
Het |
| Dlg2 |
C |
A |
7: 90,564,731 (GRCm39) |
H116N |
probably benign |
Het |
| Dnah14 |
C |
T |
1: 181,619,610 (GRCm39) |
S3978L |
probably damaging |
Het |
| Dpp8 |
C |
T |
9: 64,960,453 (GRCm39) |
T328I |
probably null |
Het |
| Dync2i1 |
T |
A |
12: 116,205,403 (GRCm39) |
|
probably null |
Het |
| Dysf |
T |
C |
6: 84,163,450 (GRCm39) |
V1625A |
probably damaging |
Het |
| Efcab3 |
G |
A |
11: 104,783,911 (GRCm39) |
G2754E |
probably benign |
Het |
| Egf |
C |
A |
3: 129,548,538 (GRCm39) |
V26F |
probably damaging |
Het |
| Eif1ad19 |
T |
C |
12: 87,740,526 (GRCm39) |
N11S |
possibly damaging |
Het |
| Fam20a |
T |
A |
11: 109,565,992 (GRCm39) |
Y414F |
probably damaging |
Het |
| Fsip2 |
T |
C |
2: 82,818,241 (GRCm39) |
I4658T |
probably benign |
Het |
| Hycc1 |
C |
T |
5: 24,196,748 (GRCm39) |
E47K |
probably benign |
Het |
| Krt79 |
T |
G |
15: 101,839,196 (GRCm39) |
E424D |
probably benign |
Het |
| Map3k6 |
A |
G |
4: 132,979,168 (GRCm39) |
|
probably null |
Het |
| Mcpt4 |
A |
G |
14: 56,297,511 (GRCm39) |
I215T |
probably damaging |
Het |
| Med13 |
T |
C |
11: 86,189,984 (GRCm39) |
Y975C |
probably damaging |
Het |
| Meioc |
T |
A |
11: 102,566,419 (GRCm39) |
Y678* |
probably null |
Het |
| Myof |
T |
C |
19: 37,924,818 (GRCm39) |
T1190A |
probably benign |
Het |
| Nap1l4 |
A |
C |
7: 143,088,132 (GRCm39) |
|
probably benign |
Het |
| Ncapg |
T |
C |
5: 45,851,195 (GRCm39) |
V796A |
probably damaging |
Het |
| Or4c10b |
C |
T |
2: 89,711,956 (GRCm39) |
T262I |
probably benign |
Het |
| Or4c119 |
C |
T |
2: 88,986,782 (GRCm39) |
V246M |
possibly damaging |
Het |
| Or5d39 |
T |
A |
2: 87,979,614 (GRCm39) |
I250L |
probably benign |
Het |
| Or5d40 |
T |
A |
2: 88,015,260 (GRCm39) |
V13E |
possibly damaging |
Het |
| Or5p68 |
T |
C |
7: 107,945,645 (GRCm39) |
Y181C |
probably benign |
Het |
| Paxbp1 |
A |
G |
16: 90,824,188 (GRCm39) |
S515P |
probably benign |
Het |
| Pip4p1 |
A |
G |
14: 51,165,436 (GRCm39) |
V257A |
probably benign |
Het |
| Plce1 |
C |
T |
19: 38,717,414 (GRCm39) |
S1401F |
probably damaging |
Het |
| Rptor |
A |
G |
11: 119,777,964 (GRCm39) |
K1043E |
probably benign |
Het |
| Rtn4rl2 |
T |
G |
2: 84,711,039 (GRCm39) |
N75T |
probably damaging |
Het |
| Slc35f4 |
A |
G |
14: 49,536,291 (GRCm39) |
I448T |
possibly damaging |
Het |
| Styk1 |
CTCTTCATGATTTTCTT |
CTCTT |
6: 131,278,612 (GRCm39) |
|
probably benign |
Het |
| Tas2r115 |
A |
G |
6: 132,714,918 (GRCm39) |
I11T |
possibly damaging |
Het |
| Tbc1d5 |
A |
G |
17: 51,181,680 (GRCm39) |
V351A |
possibly damaging |
Het |
| Trim43b |
A |
T |
9: 88,971,570 (GRCm39) |
D195E |
probably benign |
Het |
| Trim65 |
C |
A |
11: 116,021,564 (GRCm39) |
A90S |
probably benign |
Het |
| Trip11 |
C |
T |
12: 101,850,765 (GRCm39) |
V1100I |
possibly damaging |
Het |
| Tyrp1 |
A |
G |
4: 80,759,012 (GRCm39) |
E295G |
probably null |
Het |
| Ube2g2 |
G |
A |
10: 77,480,307 (GRCm39) |
V138I |
probably benign |
Het |
|
| Other mutations in Igflr1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00902:Igflr1
|
APN |
7 |
30,266,700 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2209:Igflr1
|
UTSW |
7 |
30,267,222 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5451:Igflr1
|
UTSW |
7 |
30,265,747 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7560:Igflr1
|
UTSW |
7 |
30,266,776 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8939:Igflr1
|
UTSW |
7 |
30,266,888 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCCATGGGTAAAGCTTGGGTC -3'
(R):5'- TCTCCAAAAGCTGAGCTGG -3'
Sequencing Primer
(F):5'- CCCAAGTGGAGTGCCTGAAAG -3'
(R):5'- CTGAGCTGGAACCAGGACG -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation