Incidental Mutation 'R0512:Tnrc6a'
| ID |
47906 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6a
|
| Ensembl Gene |
ENSMUSG00000052707 |
| Gene Name |
trinucleotide repeat containing 6a |
| Synonyms |
3110054G10Rik, 2010321I05Rik, Tnrc6, CAGH26, D130023A07Rik |
| MMRRC Submission |
038706-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.879)
|
| Stock # |
R0512 (G1)
|
| Quality Score |
223 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
122723108-122794519 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 122785951 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094053]
[ENSMUST00000205514]
|
| AlphaFold |
Q3UHK8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094053
|
| SMART Domains |
Protein: ENSMUSP00000091595
Gene: ENSMUSG00000052707
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
5 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
281 |
294 |
N/A |
INTRINSIC |
|
low complexity region
|
430 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
568 |
590 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
690 |
853 |
3.51e-6 |
PROSPERO |
|
low complexity region
|
858 |
871 |
N/A |
INTRINSIC |
|
Pfam:Ago_hook
|
1028 |
1190 |
1.2e-29 |
PFAM |
|
low complexity region
|
1284 |
1296 |
N/A |
INTRINSIC |
|
low complexity region
|
1301 |
1316 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1392 |
N/A |
INTRINSIC |
|
Pfam:TNRC6-PABC_bdg
|
1439 |
1714 |
1.5e-126 |
PFAM |
|
RRM
|
1717 |
1784 |
4.95e-2 |
SMART |
|
low complexity region
|
1808 |
1820 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205514
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000205760
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206126
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.8%
|
| Validation Efficiency |
100% (92/92) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The human protein associates with messenger RNAs and argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies, and inhibiting its expression delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit partial embryonic lethality during organogenesis associated with impaired hematopoiesis. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(21) : Gene trapped(21) |
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930519G04Rik |
T |
G |
5: 115,001,569 (GRCm39) |
M22R |
probably benign |
Het |
| Abca8b |
C |
A |
11: 109,841,476 (GRCm39) |
M1039I |
probably benign |
Het |
| Actn2 |
A |
T |
13: 12,292,301 (GRCm39) |
I653N |
probably damaging |
Het |
| Actr8 |
G |
T |
14: 29,700,513 (GRCm39) |
V31L |
probably benign |
Het |
| Adam30 |
T |
C |
3: 98,069,441 (GRCm39) |
C425R |
probably damaging |
Het |
| Armc1 |
A |
G |
3: 19,203,659 (GRCm39) |
V89A |
possibly damaging |
Het |
| Atr |
T |
C |
9: 95,817,579 (GRCm39) |
M2090T |
probably damaging |
Het |
| Braf |
T |
A |
6: 39,641,923 (GRCm39) |
|
probably benign |
Het |
| Cant1 |
A |
T |
11: 118,302,091 (GRCm39) |
N75K |
probably benign |
Het |
| Chd7 |
C |
T |
4: 8,805,139 (GRCm39) |
|
probably benign |
Het |
| Clec16a |
A |
G |
16: 10,432,444 (GRCm39) |
Y488C |
probably damaging |
Het |
| Col6a3 |
A |
T |
1: 90,749,520 (GRCm39) |
|
probably benign |
Het |
| Col9a2 |
T |
A |
4: 120,911,504 (GRCm39) |
M615K |
probably benign |
Het |
| Dedd |
G |
A |
1: 171,168,498 (GRCm39) |
R228H |
probably damaging |
Het |
| Dhtkd1 |
C |
T |
2: 5,908,902 (GRCm39) |
D731N |
probably damaging |
Het |
| Ercc2 |
A |
G |
7: 19,127,812 (GRCm39) |
T651A |
probably damaging |
Het |
| Fam13a |
T |
A |
6: 58,933,684 (GRCm39) |
D302V |
probably damaging |
Het |
| Fam193a |
T |
C |
5: 34,583,735 (GRCm39) |
S19P |
probably damaging |
Het |
| Fam43a |
T |
C |
16: 30,420,553 (GRCm39) |
V379A |
possibly damaging |
Het |
| Fat1 |
C |
A |
8: 45,404,369 (GRCm39) |
Y373* |
probably null |
Het |
| Fbxl15 |
A |
C |
19: 46,317,861 (GRCm39) |
D181A |
probably damaging |
Het |
| Flt3 |
A |
T |
5: 147,278,080 (GRCm39) |
C831* |
probably null |
Het |
| Foxj3 |
T |
A |
4: 119,443,033 (GRCm39) |
|
probably benign |
Het |
| Glul |
T |
C |
1: 153,781,132 (GRCm39) |
|
probably benign |
Het |
| Gm16380 |
A |
T |
9: 53,791,529 (GRCm39) |
|
noncoding transcript |
Het |
| Gm7964 |
A |
T |
7: 83,405,158 (GRCm39) |
|
noncoding transcript |
Het |
| Hipk1 |
A |
G |
3: 103,667,890 (GRCm39) |
F559S |
possibly damaging |
Het |
| Hnf4g |
A |
T |
3: 3,716,682 (GRCm39) |
I284F |
probably damaging |
Het |
| Hoxa13 |
CCG |
CCGCG |
6: 52,237,618 (GRCm39) |
|
probably null |
Het |
| Icosl |
A |
G |
10: 77,907,800 (GRCm39) |
N120S |
possibly damaging |
Het |
| Ift172 |
A |
G |
5: 31,442,821 (GRCm39) |
V155A |
possibly damaging |
Het |
| Kdm4c |
A |
G |
4: 74,252,031 (GRCm39) |
E426G |
probably benign |
Het |
| Kif23 |
A |
G |
9: 61,826,257 (GRCm39) |
|
probably benign |
Het |
| Krt81 |
C |
A |
15: 101,361,508 (GRCm39) |
R24L |
possibly damaging |
Het |
| Lama1 |
G |
A |
17: 68,086,129 (GRCm39) |
C1456Y |
possibly damaging |
Het |
| Lamc3 |
T |
A |
2: 31,827,980 (GRCm39) |
L1378Q |
probably damaging |
Het |
| Larp1b |
T |
A |
3: 40,924,469 (GRCm39) |
L121M |
probably benign |
Het |
| Lepr |
T |
A |
4: 101,649,216 (GRCm39) |
D872E |
probably damaging |
Het |
| Lepr |
A |
C |
4: 101,671,901 (GRCm39) |
D975A |
possibly damaging |
Het |
| Magi1 |
A |
G |
6: 93,671,045 (GRCm39) |
V1068A |
probably damaging |
Het |
| Malt1 |
T |
A |
18: 65,591,271 (GRCm39) |
N358K |
probably damaging |
Het |
| Mfap4 |
T |
A |
11: 61,378,771 (GRCm39) |
W240R |
probably damaging |
Het |
| Mis18a |
A |
G |
16: 90,523,244 (GRCm39) |
V84A |
possibly damaging |
Het |
| Mns1 |
A |
G |
9: 72,356,753 (GRCm39) |
E308G |
possibly damaging |
Het |
| Mpp2 |
C |
A |
11: 101,953,116 (GRCm39) |
L258F |
possibly damaging |
Het |
| Myh2 |
A |
G |
11: 67,079,504 (GRCm39) |
E987G |
probably damaging |
Het |
| Myof |
A |
G |
19: 37,942,972 (GRCm39) |
V702A |
possibly damaging |
Het |
| Nhs |
C |
A |
X: 160,620,355 (GRCm39) |
R1467I |
probably damaging |
Het |
| Nrxn2 |
A |
G |
19: 6,567,228 (GRCm39) |
T1360A |
probably damaging |
Het |
| Obox6 |
A |
G |
7: 15,567,874 (GRCm39) |
I191T |
probably benign |
Het |
| Pacs2 |
G |
T |
12: 113,014,547 (GRCm39) |
R236L |
probably damaging |
Het |
| Pcdhb2 |
T |
G |
18: 37,429,032 (GRCm39) |
V335G |
probably damaging |
Het |
| Phyhipl |
T |
C |
10: 70,404,748 (GRCm39) |
I140M |
probably damaging |
Het |
| Pkhd1 |
T |
C |
1: 20,380,738 (GRCm39) |
|
probably benign |
Het |
| Ppp1r3b |
T |
G |
8: 35,851,571 (GRCm39) |
C137G |
probably damaging |
Het |
| Prdm13 |
T |
A |
4: 21,678,490 (GRCm39) |
I667F |
probably damaging |
Het |
| Prex2 |
A |
G |
1: 11,270,157 (GRCm39) |
M1281V |
probably benign |
Het |
| Rab40b |
A |
G |
11: 121,250,412 (GRCm39) |
F81L |
probably damaging |
Het |
| Rb1cc1 |
T |
C |
1: 6,318,767 (GRCm39) |
S729P |
probably damaging |
Het |
| Rcl1 |
A |
G |
19: 29,105,497 (GRCm39) |
D228G |
probably damaging |
Het |
| Rhbdf1 |
A |
T |
11: 32,160,875 (GRCm39) |
C19* |
probably null |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Rnf150 |
G |
A |
8: 83,590,807 (GRCm39) |
V57M |
probably benign |
Het |
| Rp9 |
A |
G |
9: 22,370,015 (GRCm39) |
F51L |
probably benign |
Het |
| Sav1 |
A |
T |
12: 70,015,975 (GRCm39) |
Y274* |
probably null |
Het |
| Scn4a |
A |
T |
11: 106,236,503 (GRCm39) |
D252E |
probably damaging |
Het |
| Scn5a |
T |
C |
9: 119,379,724 (GRCm39) |
T187A |
probably damaging |
Het |
| Sigirr |
T |
A |
7: 140,672,333 (GRCm39) |
D229V |
probably benign |
Het |
| Slc39a13 |
T |
C |
2: 90,896,031 (GRCm39) |
S157G |
possibly damaging |
Het |
| Slc6a20a |
A |
G |
9: 123,489,471 (GRCm39) |
S191P |
probably damaging |
Het |
| Sorl1 |
C |
A |
9: 41,979,128 (GRCm39) |
A457S |
probably benign |
Het |
| Spag5 |
A |
G |
11: 78,210,412 (GRCm39) |
|
probably benign |
Het |
| Spon1 |
A |
G |
7: 113,436,066 (GRCm39) |
E119G |
possibly damaging |
Het |
| Spred2 |
T |
A |
11: 19,958,485 (GRCm39) |
|
probably benign |
Het |
| Sprr3 |
T |
G |
3: 92,364,784 (GRCm39) |
Q20P |
possibly damaging |
Het |
| Strn3 |
A |
T |
12: 51,673,966 (GRCm39) |
F464L |
possibly damaging |
Het |
| Sun1 |
A |
G |
5: 139,220,602 (GRCm39) |
|
probably benign |
Het |
| Sypl2 |
A |
G |
3: 108,133,486 (GRCm39) |
W28R |
possibly damaging |
Het |
| Syt5 |
A |
T |
7: 4,545,813 (GRCm39) |
V150D |
probably damaging |
Het |
| Tasor |
T |
C |
14: 27,168,363 (GRCm39) |
F302L |
probably damaging |
Het |
| Thsd7a |
A |
G |
6: 12,379,604 (GRCm39) |
I940T |
possibly damaging |
Het |
| Tlcd3b |
C |
T |
7: 126,426,795 (GRCm39) |
R73C |
probably damaging |
Het |
| Trp53 |
T |
A |
11: 69,479,509 (GRCm39) |
L203Q |
probably damaging |
Het |
| Tubgcp4 |
T |
C |
2: 121,005,900 (GRCm39) |
V96A |
probably benign |
Het |
| Usp17la |
A |
G |
7: 104,510,246 (GRCm39) |
T284A |
possibly damaging |
Het |
| Usp34 |
T |
C |
11: 23,401,997 (GRCm39) |
M2409T |
probably benign |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r56 |
A |
G |
7: 12,449,350 (GRCm39) |
I296T |
probably benign |
Het |
| Vmn2r67 |
A |
G |
7: 84,799,900 (GRCm39) |
V446A |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zfp267 |
T |
C |
3: 36,220,262 (GRCm39) |
C762R |
probably damaging |
Het |
|
| Other mutations in Tnrc6a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00335:Tnrc6a
|
APN |
7 |
122,770,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00580:Tnrc6a
|
APN |
7 |
122,773,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Tnrc6a
|
APN |
7 |
122,770,717 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02004:Tnrc6a
|
APN |
7 |
122,780,589 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL02142:Tnrc6a
|
APN |
7 |
122,751,414 (GRCm39) |
intron |
probably benign |
|
|
IGL02220:Tnrc6a
|
APN |
7 |
122,769,679 (GRCm39) |
missense |
probably benign |
|
|
IGL02436:Tnrc6a
|
APN |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02670:Tnrc6a
|
APN |
7 |
122,770,535 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02743:Tnrc6a
|
APN |
7 |
122,770,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
0152:Tnrc6a
|
UTSW |
7 |
122,779,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0008:Tnrc6a
|
UTSW |
7 |
122,769,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Tnrc6a
|
UTSW |
7 |
122,770,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0566:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0600:Tnrc6a
|
UTSW |
7 |
122,771,039 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0751:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1184:Tnrc6a
|
UTSW |
7 |
122,769,563 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1319:Tnrc6a
|
UTSW |
7 |
122,783,474 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1405:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Tnrc6a
|
UTSW |
7 |
122,776,098 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1709:Tnrc6a
|
UTSW |
7 |
122,769,205 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1776:Tnrc6a
|
UTSW |
7 |
122,770,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Tnrc6a
|
UTSW |
7 |
122,792,140 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1807:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R1876:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2010:Tnrc6a
|
UTSW |
7 |
122,770,269 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2086:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R2089:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2091:Tnrc6a
|
UTSW |
7 |
122,771,343 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2511:Tnrc6a
|
UTSW |
7 |
122,770,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2830:Tnrc6a
|
UTSW |
7 |
122,792,172 (GRCm39) |
makesense |
probably null |
|
|
R2850:Tnrc6a
|
UTSW |
7 |
122,779,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Tnrc6a
|
UTSW |
7 |
122,780,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Tnrc6a
|
UTSW |
7 |
122,769,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4235:Tnrc6a
|
UTSW |
7 |
122,770,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4439:Tnrc6a
|
UTSW |
7 |
122,751,405 (GRCm39) |
nonsense |
probably null |
|
|
R4525:Tnrc6a
|
UTSW |
7 |
122,779,005 (GRCm39) |
missense |
probably benign |
|
|
R4578:Tnrc6a
|
UTSW |
7 |
122,783,444 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4613:Tnrc6a
|
UTSW |
7 |
122,783,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4711:Tnrc6a
|
UTSW |
7 |
122,770,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Tnrc6a
|
UTSW |
7 |
122,791,313 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4746:Tnrc6a
|
UTSW |
7 |
122,789,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Tnrc6a
|
UTSW |
7 |
122,769,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Tnrc6a
|
UTSW |
7 |
122,791,836 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4967:Tnrc6a
|
UTSW |
7 |
122,789,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5064:Tnrc6a
|
UTSW |
7 |
122,785,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5239:Tnrc6a
|
UTSW |
7 |
122,785,842 (GRCm39) |
missense |
probably benign |
|
|
R5604:Tnrc6a
|
UTSW |
7 |
122,773,459 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5805:Tnrc6a
|
UTSW |
7 |
122,769,299 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5942:Tnrc6a
|
UTSW |
7 |
122,785,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Tnrc6a
|
UTSW |
7 |
122,781,603 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6212:Tnrc6a
|
UTSW |
7 |
122,742,965 (GRCm39) |
splice site |
probably null |
|
|
R6284:Tnrc6a
|
UTSW |
7 |
122,770,558 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6417:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6420:Tnrc6a
|
UTSW |
7 |
122,770,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6575:Tnrc6a
|
UTSW |
7 |
122,769,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6760:Tnrc6a
|
UTSW |
7 |
122,771,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6886:Tnrc6a
|
UTSW |
7 |
122,786,668 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6968:Tnrc6a
|
UTSW |
7 |
122,781,650 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7216:Tnrc6a
|
UTSW |
7 |
122,770,718 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7260:Tnrc6a
|
UTSW |
7 |
122,785,813 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7299:Tnrc6a
|
UTSW |
7 |
122,770,136 (GRCm39) |
missense |
probably benign |
|
|
R7322:Tnrc6a
|
UTSW |
7 |
122,770,731 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7500:Tnrc6a
|
UTSW |
7 |
122,772,673 (GRCm39) |
splice site |
probably null |
|
|
R7872:Tnrc6a
|
UTSW |
7 |
122,779,057 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8270:Tnrc6a
|
UTSW |
7 |
122,769,294 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8313:Tnrc6a
|
UTSW |
7 |
122,769,936 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8348:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8390:Tnrc6a
|
UTSW |
7 |
122,761,794 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8448:Tnrc6a
|
UTSW |
7 |
122,791,346 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8514:Tnrc6a
|
UTSW |
7 |
122,783,438 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Tnrc6a
|
UTSW |
7 |
122,761,669 (GRCm39) |
splice site |
probably benign |
|
|
R8767:Tnrc6a
|
UTSW |
7 |
122,783,133 (GRCm39) |
unclassified |
probably benign |
|
|
R9047:Tnrc6a
|
UTSW |
7 |
122,778,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9147:Tnrc6a
|
UTSW |
7 |
122,785,667 (GRCm39) |
intron |
probably benign |
|
|
R9153:Tnrc6a
|
UTSW |
7 |
122,773,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9166:Tnrc6a
|
UTSW |
7 |
122,786,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9179:Tnrc6a
|
UTSW |
7 |
122,791,881 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9192:Tnrc6a
|
UTSW |
7 |
122,789,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9457:Tnrc6a
|
UTSW |
7 |
122,778,958 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9778:Tnrc6a
|
UTSW |
7 |
122,769,635 (GRCm39) |
missense |
probably benign |
0.43 |
|
X0064:Tnrc6a
|
UTSW |
7 |
122,769,021 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1176:Tnrc6a
|
UTSW |
7 |
122,761,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTGTCAGAATCCTTGCTGTCTGTC -3'
(R):5'- TTCATCCACCATCACTGTGTGGAAC -3'
Sequencing Primer
(F):5'- CCATTTCCCTGATGGGAAGC -3'
(R):5'- CATCACTGTGTGGAACAGAAAACTG -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation