Mutagenetix > Incidental Mutation

Incidental Mutation 'R7792:Pcnx2'

599953

Institutional Source

Beutler Lab

Gene Symbol

Pcnx2

Ensembl Gene

ENSMUSG00000060212

Gene Name

pecanex homolog 2

Synonyms

Pcnxl2, E330039K12Rik

MMRRC Submission

045848-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7792 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

126478247-126625056 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 126618757 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 56 (N56K)

Ref Sequence

ENSEMBL: ENSMUSP00000042294 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000047239] [ENSMUST00000131127]

AlphaFold

Q5DU28

Predicted Effect

possibly damaging
Transcript: ENSMUST00000047239
AA Change: N56K

PolyPhen 2 Score 0.629 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000042294
Gene: ENSMUSG00000060212
AA Change: N56K

Domain	Start	End	E-Value	Type
transmembrane domain	36	53	N/A	INTRINSIC
transmembrane domain	60	82	N/A	INTRINSIC
low complexity region	94	104	N/A	INTRINSIC
low complexity region	391	415	N/A	INTRINSIC
low complexity region	457	476	N/A	INTRINSIC
low complexity region	727	742	N/A	INTRINSIC
low complexity region	806	817	N/A	INTRINSIC
transmembrane domain	823	842	N/A	INTRINSIC
transmembrane domain	849	866	N/A	INTRINSIC
transmembrane domain	881	902	N/A	INTRINSIC
transmembrane domain	934	956	N/A	INTRINSIC
transmembrane domain	976	998	N/A	INTRINSIC
transmembrane domain	1011	1030	N/A	INTRINSIC
transmembrane domain	1080	1102	N/A	INTRINSIC
transmembrane domain	1104	1126	N/A	INTRINSIC
Pfam:Pecanex_C	1603	1828	3.5e-113	PFAM
low complexity region	1864	1889	N/A	INTRINSIC
low complexity region	1968	1981	N/A	INTRINSIC
low complexity region	2004	2019	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000131127
AA Change: N56K

PolyPhen 2 Score 0.934 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000119965
Gene: ENSMUSG00000060212
AA Change: N56K

Domain	Start	End	E-Value	Type
transmembrane domain	36	53	N/A	INTRINSIC
transmembrane domain	60	82	N/A	INTRINSIC
low complexity region	94	104	N/A	INTRINSIC
low complexity region	391	415	N/A	INTRINSIC
low complexity region	457	476	N/A	INTRINSIC
low complexity region	727	742	N/A	INTRINSIC
low complexity region	806	817	N/A	INTRINSIC
transmembrane domain	823	842	N/A	INTRINSIC
transmembrane domain	849	866	N/A	INTRINSIC
transmembrane domain	934	956	N/A	INTRINSIC
transmembrane domain	968	990	N/A	INTRINSIC
transmembrane domain	1010	1029	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 98.9%

Validation Efficiency

100% (97/97)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene contains coding mononucleotide repeats that are associated with tumors of high mcrosatellite instability (MSI-H). Defects in this gene are involved in the tumorigenesis of MSI-H colorectal carcinomas. [provided by RefSeq, Jun 2016]

Allele List at MGI

Other mutations in this stock

Total: 99 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars1	G	T	8: 111,769,896 (GRCm39)	V332F	possibly damaging	Het
Abhd15	T	A	11: 77,409,560 (GRCm39)	S425T	probably benign	Het
Acads	A	T	5: 115,250,840 (GRCm39)	F152L	probably damaging	Het
Acp3	T	A	9: 104,204,165 (GRCm39)	H43L	probably damaging	Het
Adora2a	A	G	10: 75,169,480 (GRCm39)	S315G	probably benign	Het
Agxt2	A	T	15: 10,381,472 (GRCm39)	D242V	probably damaging	Het
Alx4	A	G	2: 93,473,056 (GRCm39)	D18G	probably damaging	Het
Ankrd11	A	G	8: 123,610,970 (GRCm39)	S2639P	probably damaging	Het
Arhgap35	A	T	7: 16,295,453 (GRCm39)	V1204D	possibly damaging	Het
Arid2	A	G	15: 96,267,256 (GRCm39)	T579A	probably benign	Het
B4galt1	C	T	4: 40,809,373 (GRCm39)	G332S	probably benign	Het
B4galt4	C	A	16: 38,578,172 (GRCm39)	Y206*	probably null	Het
Bcl2l14	A	T	6: 134,409,277 (GRCm39)	T284S	possibly damaging	Het
Bop1	C	T	15: 76,338,548 (GRCm39)	V465M	probably damaging	Het
Cacna1b	A	T	2: 24,567,977 (GRCm39)	L1037H	probably damaging	Het
Cadm2	G	A	16: 66,568,523 (GRCm39)	T254M	probably benign	Het
Ccdc180	T	C	4: 45,890,389 (GRCm39)		probably null	Het
Ccdc7a	A	T	8: 129,618,918 (GRCm39)	D875E	possibly damaging	Het
Cenpu	A	G	8: 47,015,502 (GRCm39)	D139G	possibly damaging	Het
Cep57l1	A	T	10: 41,598,936 (GRCm39)	C292*	probably null	Het
Cep89	G	A	7: 35,129,353 (GRCm39)	R630H	probably damaging	Het
Chst14	A	G	2: 118,758,256 (GRCm39)	H350R	probably benign	Het
Clca3a1	T	A	3: 144,455,492 (GRCm39)	I434F	possibly damaging	Het
Crispld2	A	G	8: 120,757,809 (GRCm39)	T385A	probably benign	Het
Crmp1	A	C	5: 37,441,439 (GRCm39)	N507T	probably damaging	Het
Cyp4f40	T	A	17: 32,890,143 (GRCm39)	I271N	probably damaging	Het
D630003M21Rik	G	T	2: 158,052,082 (GRCm39)	Q670K	possibly damaging	Het
Ddx42	T	C	11: 106,127,822 (GRCm39)	I342T	probably damaging	Het
Dnah9	T	A	11: 65,740,839 (GRCm39)	I4116F	probably damaging	Het
Ehd2	T	C	7: 15,684,683 (GRCm39)	H372R	probably benign	Het
Gja8	C	A	3: 96,827,092 (GRCm39)	C190F	probably damaging	Het
Gm8297	A	T	14: 16,165,939 (GRCm39)	D72V	possibly damaging	Het
Golgb1	A	G	16: 36,739,092 (GRCm39)	D2518G	probably benign	Het
Hsd17b12	C	A	2: 93,863,986 (GRCm39)	M285I	probably benign	Het
Hus1	T	C	11: 8,950,133 (GRCm39)	E196G	probably damaging	Het
Ift70a2	T	C	2: 75,807,273 (GRCm39)	N413S	probably benign	Het
Irf2	G	A	8: 47,260,314 (GRCm39)	R82Q	probably damaging	Het
Irx2	A	G	13: 72,779,493 (GRCm39)	D259G	possibly damaging	Het
Jph1	T	A	1: 17,074,602 (GRCm39)	Q472L	probably benign	Het
Kif2a	T	C	13: 107,124,490 (GRCm39)	Q142R	probably benign	Het
Lonp1	T	C	17: 56,929,515 (GRCm39)	Y174C	probably damaging	Het
Mapk14	T	C	17: 28,965,271 (GRCm39)	F348L	probably damaging	Het
Marchf10	G	T	11: 105,281,054 (GRCm39)	D410E	probably benign	Het
Mff	A	T	1: 82,724,802 (GRCm39)		probably null	Het
Mtrex	A	T	13: 113,009,443 (GRCm39)	D985E	probably benign	Het
Necab3	G	A	2: 154,388,200 (GRCm39)	R271C	probably damaging	Het
Nlrp4e	T	A	7: 23,021,182 (GRCm39)	F556L	possibly damaging	Het
Nt5c2	T	C	19: 46,878,385 (GRCm39)	K425E	probably benign	Het
Ofcc1	A	T	13: 40,296,302 (GRCm39)	W511R	probably damaging	Het
Or1j18	A	C	2: 36,624,342 (GRCm39)	E3A	probably benign	Het
Or2v1	T	A	11: 49,025,496 (GRCm39)	I159N	possibly damaging	Het
Or4k77	T	C	2: 111,199,748 (GRCm39)	I257T	probably benign	Het
Or52p2	T	A	7: 102,238,090 (GRCm39)		probably benign	Het
P2rx2	G	C	5: 110,488,210 (GRCm39)	A448G	possibly damaging	Het
Pdzd7	A	C	19: 45,028,657 (GRCm39)	M162R	possibly damaging	Het
Phyhd1	A	G	2: 30,156,782 (GRCm39)	M1V	probably null	Het
Plaat3	T	C	19: 7,556,660 (GRCm39)	C154R	probably benign	Het
Plekha5	A	G	6: 140,534,950 (GRCm39)	E1126G	possibly damaging	Het
Plekhm1	A	T	11: 103,287,886 (GRCm39)	V87D	probably damaging	Het
Pole	G	A	5: 110,445,332 (GRCm39)		probably null	Het
Pramel22	A	G	4: 143,381,123 (GRCm39)	L300P	probably benign	Het
R3hcc1	T	C	14: 69,942,957 (GRCm39)	M207V	probably benign	Het
R3hcc1l	T	A	19: 42,552,403 (GRCm39)	S467T	probably damaging	Het
Rasgrp4	G	T	7: 28,842,527 (GRCm39)	R267L	probably damaging	Het
Rbm20	T	C	19: 53,838,567 (GRCm39)	I848T	probably benign	Het
Rims2	T	C	15: 39,061,923 (GRCm39)	S56P	possibly damaging	Het
Rmc1	G	A	18: 12,314,656 (GRCm39)	D289N	probably damaging	Het
Sacs	T	A	14: 61,447,222 (GRCm39)	D3089E	probably benign	Het
Sall2	C	T	14: 52,553,521 (GRCm39)	G16R	probably damaging	Het
Scgb1b19	G	A	7: 32,987,912 (GRCm39)	C93Y	probably damaging	Het
Scn3a	T	A	2: 65,297,334 (GRCm39)	K1442*	probably null	Het
Sepsecs	A	G	5: 52,801,391 (GRCm39)	S424P	probably damaging	Het
Set	G	T	2: 29,960,323 (GRCm39)	V219F	probably benign	Het
Sh3tc1	A	T	5: 35,868,295 (GRCm39)	F390I	probably damaging	Het
Simc1	G	A	13: 54,695,143 (GRCm39)	V1269M	probably damaging	Het
Ska3	T	G	14: 58,047,512 (GRCm39)	D341A	probably damaging	Het
Slc16a10	A	T	10: 39,913,411 (GRCm39)		probably null	Het
Srgap1	T	A	10: 121,761,872 (GRCm39)	N92I	probably damaging	Het
Sspo	T	C	6: 48,431,624 (GRCm39)	V639A	probably damaging	Het
Stk11	A	T	10: 79,961,271 (GRCm39)		probably benign	Het
Sult5a1	G	A	8: 123,872,180 (GRCm39)	H221Y	probably benign	Het
Sytl3	T	A	17: 7,003,977 (GRCm39)	M559K	probably benign	Het
Tab2	A	C	10: 7,794,897 (GRCm39)	D528E	possibly damaging	Het
Tbc1d15	A	G	10: 115,057,492 (GRCm39)	I218T	possibly damaging	Het
Tenm4	T	A	7: 96,423,221 (GRCm39)	M672K	possibly damaging	Het
Tent4b	A	T	8: 88,979,182 (GRCm39)	Q561L	probably benign	Het
Tfrc	A	G	16: 32,437,985 (GRCm39)	K346R	probably benign	Het
Thsd1	G	T	8: 22,733,114 (GRCm39)	G54W	probably damaging	Het
Tmprss15	A	T	16: 78,800,275 (GRCm39)	L618I	probably damaging	Het
Top3a	T	C	11: 60,633,790 (GRCm39)	S769G	probably benign	Het
Trp63	C	A	16: 25,686,974 (GRCm39)	P396Q	possibly damaging	Het
Uggt1	T	C	1: 36,247,065 (GRCm39)	S311G	probably damaging	Het
Usp10	G	A	8: 120,678,740 (GRCm39)	E574K	possibly damaging	Het
Wfdc6b	T	A	2: 164,459,822 (GRCm39)	I148K	probably damaging	Het
Zcchc2	T	G	1: 105,945,982 (GRCm39)	I474R	probably damaging	Het
Zdhhc2	A	G	8: 40,900,182 (GRCm39)	K82R	probably benign	Het
Zfp273	A	G	13: 67,974,135 (GRCm39)	D421G	possibly damaging	Het
Zfp280d	T	C	9: 72,238,601 (GRCm39)	I639T	probably damaging	Het
Zfp429	A	T	13: 67,538,558 (GRCm39)	C295*	probably null	Het

Other mutations in Pcnx2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00898:Pcnx2	APN	8	126,614,324 (GRCm39)	missense	probably damaging	1.00
IGL00900:Pcnx2	APN	8	126,589,975 (GRCm39)	splice site	probably benign
IGL01134:Pcnx2	APN	8	126,589,889 (GRCm39)	missense	probably benign
IGL01370:Pcnx2	APN	8	126,528,222 (GRCm39)	missense	probably damaging	0.96
IGL01452:Pcnx2	APN	8	126,564,771 (GRCm39)	missense	probably damaging	1.00
IGL01477:Pcnx2	APN	8	126,512,044 (GRCm39)	missense	probably damaging	1.00
IGL01610:Pcnx2	APN	8	126,566,372 (GRCm39)	missense	possibly damaging	0.67
IGL01640:Pcnx2	APN	8	126,528,297 (GRCm39)	missense	probably benign	0.14
IGL01645:Pcnx2	APN	8	126,614,656 (GRCm39)	missense	probably damaging	1.00
IGL01876:Pcnx2	APN	8	126,592,770 (GRCm39)	missense	probably benign	0.31
IGL01933:Pcnx2	APN	8	126,488,393 (GRCm39)	missense	probably damaging	1.00
IGL02208:Pcnx2	APN	8	126,478,894 (GRCm39)	missense	probably benign	0.30
IGL02573:Pcnx2	APN	8	126,582,012 (GRCm39)	missense	probably benign	0.34
IGL02810:Pcnx2	APN	8	126,613,942 (GRCm39)	missense	probably benign	0.03
IGL02859:Pcnx2	APN	8	126,589,912 (GRCm39)	missense	probably damaging	1.00
IGL02879:Pcnx2	APN	8	126,498,796 (GRCm39)	missense	probably damaging	1.00
IGL03202:Pcnx2	APN	8	126,498,783 (GRCm39)	missense	probably damaging	0.98
IGL03259:Pcnx2	APN	8	126,480,388 (GRCm39)	missense	probably benign	0.19
IGL03395:Pcnx2	APN	8	126,614,262 (GRCm39)	missense	probably benign	0.00
IGL03410:Pcnx2	APN	8	126,613,779 (GRCm39)	missense	probably damaging	1.00
gallen	UTSW	8	126,617,859 (GRCm39)	missense	probably damaging	1.00
hotzone	UTSW	8	126,617,880 (GRCm39)	missense	probably benign	0.00
R0107:Pcnx2	UTSW	8	126,480,325 (GRCm39)	missense	probably benign	0.29
R0477:Pcnx2	UTSW	8	126,488,306 (GRCm39)	missense	probably damaging	0.99
R0610:Pcnx2	UTSW	8	126,566,426 (GRCm39)	missense	probably damaging	1.00
R0645:Pcnx2	UTSW	8	126,487,459 (GRCm39)	missense	possibly damaging	0.64
R0894:Pcnx2	UTSW	8	126,613,665 (GRCm39)	splice site	probably benign
R1083:Pcnx2	UTSW	8	126,498,843 (GRCm39)	missense	probably damaging	1.00
R1199:Pcnx2	UTSW	8	126,614,053 (GRCm39)	missense	possibly damaging	0.60
R1296:Pcnx2	UTSW	8	126,500,572 (GRCm39)	missense	probably damaging	1.00
R1445:Pcnx2	UTSW	8	126,479,023 (GRCm39)	missense	probably damaging	0.99
R1467:Pcnx2	UTSW	8	126,480,289 (GRCm39)	missense	possibly damaging	0.77
R1467:Pcnx2	UTSW	8	126,480,289 (GRCm39)	missense	possibly damaging	0.77
R1524:Pcnx2	UTSW	8	126,617,880 (GRCm39)	missense	probably benign	0.00
R1537:Pcnx2	UTSW	8	126,604,188 (GRCm39)	missense	possibly damaging	0.94
R1574:Pcnx2	UTSW	8	126,500,669 (GRCm39)	missense	probably damaging	1.00
R1574:Pcnx2	UTSW	8	126,500,669 (GRCm39)	missense	probably damaging	1.00
R1593:Pcnx2	UTSW	8	126,486,012 (GRCm39)	missense	probably benign	0.11
R1598:Pcnx2	UTSW	8	126,498,825 (GRCm39)	missense	probably benign	0.03
R1603:Pcnx2	UTSW	8	126,566,365 (GRCm39)	missense	probably damaging	1.00
R1697:Pcnx2	UTSW	8	126,577,087 (GRCm39)	missense	probably damaging	1.00
R1759:Pcnx2	UTSW	8	126,500,717 (GRCm39)	missense	probably damaging	1.00
R1855:Pcnx2	UTSW	8	126,534,735 (GRCm39)	splice site	probably benign
R1863:Pcnx2	UTSW	8	126,545,525 (GRCm39)	missense	probably damaging	0.98
R1930:Pcnx2	UTSW	8	126,614,453 (GRCm39)	missense	probably benign	0.10
R1967:Pcnx2	UTSW	8	126,542,422 (GRCm39)	missense	possibly damaging	0.51
R1974:Pcnx2	UTSW	8	126,614,110 (GRCm39)	missense	probably benign	0.00
R1998:Pcnx2	UTSW	8	126,613,882 (GRCm39)	missense	probably damaging	1.00
R2034:Pcnx2	UTSW	8	126,545,406 (GRCm39)	critical splice donor site	probably null
R2072:Pcnx2	UTSW	8	126,488,481 (GRCm39)	missense	possibly damaging	0.90
R2096:Pcnx2	UTSW	8	126,485,987 (GRCm39)	missense	probably benign	0.27
R2216:Pcnx2	UTSW	8	126,614,816 (GRCm39)	missense	probably benign	0.00
R2290:Pcnx2	UTSW	8	126,604,334 (GRCm39)	splice site	probably benign
R2373:Pcnx2	UTSW	8	126,480,190 (GRCm39)	missense	probably damaging	1.00
R2484:Pcnx2	UTSW	8	126,617,859 (GRCm39)	missense	probably damaging	1.00
R2849:Pcnx2	UTSW	8	126,487,666 (GRCm39)	missense	probably damaging	1.00
R2891:Pcnx2	UTSW	8	126,617,797 (GRCm39)	missense	probably damaging	1.00
R2892:Pcnx2	UTSW	8	126,617,797 (GRCm39)	missense	probably damaging	1.00
R2970:Pcnx2	UTSW	8	126,528,275 (GRCm39)	missense	probably damaging	1.00
R3013:Pcnx2	UTSW	8	126,614,509 (GRCm39)	missense	probably benign	0.05
R3608:Pcnx2	UTSW	8	126,614,840 (GRCm39)	missense	probably benign
R3876:Pcnx2	UTSW	8	126,614,897 (GRCm39)	missense	probably benign
R4349:Pcnx2	UTSW	8	126,489,590 (GRCm39)	missense	probably damaging	0.98
R4352:Pcnx2	UTSW	8	126,489,590 (GRCm39)	missense	probably damaging	0.98
R4353:Pcnx2	UTSW	8	126,489,590 (GRCm39)	missense	probably damaging	0.98
R4361:Pcnx2	UTSW	8	126,495,037 (GRCm39)	nonsense	probably null
R4735:Pcnx2	UTSW	8	126,554,780 (GRCm39)	critical splice donor site	probably null
R4749:Pcnx2	UTSW	8	126,614,327 (GRCm39)	missense	probably damaging	1.00
R4812:Pcnx2	UTSW	8	126,592,678 (GRCm39)	missense	probably benign	0.00
R4819:Pcnx2	UTSW	8	126,581,969 (GRCm39)	missense	probably benign	0.04
R4829:Pcnx2	UTSW	8	126,587,797 (GRCm39)	splice site	probably null
R4832:Pcnx2	UTSW	8	126,478,927 (GRCm39)	missense	probably damaging	0.99
R4876:Pcnx2	UTSW	8	126,498,847 (GRCm39)	missense	probably damaging	1.00
R4974:Pcnx2	UTSW	8	126,577,869 (GRCm39)	missense	probably benign	0.00
R5057:Pcnx2	UTSW	8	126,581,930 (GRCm39)	missense	possibly damaging	0.95
R5078:Pcnx2	UTSW	8	126,478,895 (GRCm39)	missense	probably benign
R5114:Pcnx2	UTSW	8	126,564,749 (GRCm39)	missense	possibly damaging	0.89
R5195:Pcnx2	UTSW	8	126,528,288 (GRCm39)	missense	possibly damaging	0.69
R5239:Pcnx2	UTSW	8	126,587,821 (GRCm39)	splice site	probably null
R5348:Pcnx2	UTSW	8	126,545,495 (GRCm39)	missense	probably damaging	1.00
R5398:Pcnx2	UTSW	8	126,614,687 (GRCm39)	missense	possibly damaging	0.63
R5448:Pcnx2	UTSW	8	126,614,888 (GRCm39)	missense	probably benign	0.14
R5534:Pcnx2	UTSW	8	126,564,754 (GRCm39)	missense	possibly damaging	0.65
R5624:Pcnx2	UTSW	8	126,488,262 (GRCm39)	critical splice donor site	probably null
R5629:Pcnx2	UTSW	8	126,624,780 (GRCm39)	missense	probably damaging	1.00
R5630:Pcnx2	UTSW	8	126,587,697 (GRCm39)	missense	probably damaging	0.99
R5782:Pcnx2	UTSW	8	126,480,223 (GRCm39)	missense	probably damaging	1.00
R5877:Pcnx2	UTSW	8	126,480,467 (GRCm39)	missense	probably damaging	0.99
R5879:Pcnx2	UTSW	8	126,500,685 (GRCm39)	missense	probably damaging	1.00
R6114:Pcnx2	UTSW	8	126,500,686 (GRCm39)	missense	probably damaging	1.00
R6152:Pcnx2	UTSW	8	126,480,491 (GRCm39)	missense	probably damaging	0.99
R6154:Pcnx2	UTSW	8	126,489,552 (GRCm39)	missense	probably damaging	1.00
R6283:Pcnx2	UTSW	8	126,604,325 (GRCm39)	missense	probably damaging	0.99
R6500:Pcnx2	UTSW	8	126,480,224 (GRCm39)	missense	probably damaging	1.00
R6629:Pcnx2	UTSW	8	126,617,851 (GRCm39)	missense	probably benign	0.00
R6708:Pcnx2	UTSW	8	126,587,692 (GRCm39)	critical splice donor site	probably null
R6736:Pcnx2	UTSW	8	126,479,056 (GRCm39)	splice site	probably null
R6748:Pcnx2	UTSW	8	126,577,074 (GRCm39)	missense	probably damaging	1.00
R6788:Pcnx2	UTSW	8	126,498,839 (GRCm39)	missense	probably damaging	1.00
R6849:Pcnx2	UTSW	8	126,587,949 (GRCm39)	missense	probably damaging	1.00
R6947:Pcnx2	UTSW	8	126,577,021 (GRCm39)	critical splice donor site	probably null
R7034:Pcnx2	UTSW	8	126,512,041 (GRCm39)	missense	probably damaging	1.00
R7100:Pcnx2	UTSW	8	126,485,853 (GRCm39)	missense	probably benign	0.16
R7124:Pcnx2	UTSW	8	126,480,356 (GRCm39)	missense	probably damaging	0.99
R7130:Pcnx2	UTSW	8	126,480,323 (GRCm39)	nonsense	probably null
R7133:Pcnx2	UTSW	8	126,528,243 (GRCm39)	missense	probably benign	0.01
R7271:Pcnx2	UTSW	8	126,613,690 (GRCm39)	missense	probably benign
R7326:Pcnx2	UTSW	8	126,613,822 (GRCm39)	missense	probably damaging	1.00
R7373:Pcnx2	UTSW	8	126,534,766 (GRCm39)	missense	probably damaging	1.00
R7397:Pcnx2	UTSW	8	126,617,624 (GRCm39)	splice site	probably null
R7662:Pcnx2	UTSW	8	126,545,510 (GRCm39)	nonsense	probably null
R7693:Pcnx2	UTSW	8	126,613,864 (GRCm39)	missense	probably benign	0.09
R7726:Pcnx2	UTSW	8	126,577,069 (GRCm39)	missense	probably benign	0.00
R7745:Pcnx2	UTSW	8	126,577,846 (GRCm39)	missense	probably benign	0.04
R7797:Pcnx2	UTSW	8	126,512,087 (GRCm39)	missense	possibly damaging	0.70
R7921:Pcnx2	UTSW	8	126,564,602 (GRCm39)	missense	probably benign
R7984:Pcnx2	UTSW	8	126,485,865 (GRCm39)	missense	probably benign
R8098:Pcnx2	UTSW	8	126,495,040 (GRCm39)	missense	probably damaging	1.00
R8277:Pcnx2	UTSW	8	126,592,755 (GRCm39)	missense	probably damaging	1.00
R8312:Pcnx2	UTSW	8	126,489,589 (GRCm39)	missense	possibly damaging	0.69
R8354:Pcnx2	UTSW	8	126,488,357 (GRCm39)	missense	probably damaging	0.99
R8378:Pcnx2	UTSW	8	126,487,649 (GRCm39)	missense	probably damaging	1.00
R8713:Pcnx2	UTSW	8	126,545,525 (GRCm39)	missense	probably damaging	1.00
R8714:Pcnx2	UTSW	8	126,500,546 (GRCm39)	missense	probably benign
R8753:Pcnx2	UTSW	8	126,613,999 (GRCm39)	missense	probably benign	0.15
R8790:Pcnx2	UTSW	8	126,604,306 (GRCm39)	missense	probably benign
R8925:Pcnx2	UTSW	8	126,614,659 (GRCm39)	missense	probably benign	0.01
R8927:Pcnx2	UTSW	8	126,614,659 (GRCm39)	missense	probably benign	0.01
R8965:Pcnx2	UTSW	8	126,485,853 (GRCm39)	missense	probably benign	0.16
R9006:Pcnx2	UTSW	8	126,613,996 (GRCm39)	missense	probably benign	0.00
R9082:Pcnx2	UTSW	8	126,613,753 (GRCm39)	missense	probably damaging	1.00
R9202:Pcnx2	UTSW	8	126,616,416 (GRCm39)	critical splice acceptor site	probably null
R9315:Pcnx2	UTSW	8	126,614,119 (GRCm39)	missense	probably benign	0.00
R9434:Pcnx2	UTSW	8	126,542,512 (GRCm39)	missense	probably benign	0.00
R9660:Pcnx2	UTSW	8	126,487,592 (GRCm39)	missense	probably damaging	1.00
R9686:Pcnx2	UTSW	8	126,592,766 (GRCm39)	missense	probably benign
R9766:Pcnx2	UTSW	8	126,488,313 (GRCm39)	missense	probably damaging	1.00
R9778:Pcnx2	UTSW	8	126,512,176 (GRCm39)	missense	probably benign	0.00
R9792:Pcnx2	UTSW	8	126,534,820 (GRCm39)	missense	probably damaging	0.99
RF018:Pcnx2	UTSW	8	126,604,258 (GRCm39)	missense	probably damaging	1.00
Z1088:Pcnx2	UTSW	8	126,592,757 (GRCm39)	missense	probably damaging	1.00
Z1088:Pcnx2	UTSW	8	126,553,667 (GRCm39)	missense	probably damaging	1.00
Z1176:Pcnx2	UTSW	8	126,564,753 (GRCm39)	missense	probably benign	0.30
Z1176:Pcnx2	UTSW	8	126,488,393 (GRCm39)	missense	probably damaging	1.00
Z1177:Pcnx2	UTSW	8	126,614,699 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- TTTTGGGAGCTGGCACTCTC -3'
(R):5'- CTGATGAGAACTCGGGAAGC -3'

Sequencing Primer
(F):5'- TGGCACTCTCCTGGACAAG -3'
(R):5'- CTCCTTTCCATTGATATTCTAACCAG -3'

Posted On

2019-11-26