Incidental Mutation 'R1968:Dop1b'
| ID |
219323 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dop1b
|
| Ensembl Gene |
ENSMUSG00000022946 |
| Gene Name |
DOP1 leucine zipper like protein B |
| Synonyms |
Dopey2, 0610038M01Rik, 2610510B01Rik |
| MMRRC Submission |
039981-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1968 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
93508795-93607476 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 93579307 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 1690
(N1690D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154771
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045004]
[ENSMUST00000227156]
[ENSMUST00000228261]
|
| AlphaFold |
Q3UHQ6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000045004
AA Change: N1808D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000044437
Gene: ENSMUSG00000022946
AA Change: N1808D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Dopey_N
|
11 |
308 |
3.9e-104 |
PFAM |
|
low complexity region
|
651 |
666 |
N/A |
INTRINSIC |
|
low complexity region
|
709 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
747 |
759 |
N/A |
INTRINSIC |
|
low complexity region
|
1186 |
1199 |
N/A |
INTRINSIC |
|
low complexity region
|
1436 |
1451 |
N/A |
INTRINSIC |
|
low complexity region
|
1893 |
1908 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000226215
AA Change: N1018D
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226535
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000227156
AA Change: N1690D
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000227939
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000228261
AA Change: N113D
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm4 |
A |
G |
4: 144,397,193 (GRCm39) |
Y180H |
possibly damaging |
Het |
| Abcc10 |
A |
T |
17: 46,633,125 (GRCm39) |
L528Q |
probably damaging |
Het |
| Adam18 |
T |
A |
8: 25,136,463 (GRCm39) |
T353S |
probably benign |
Het |
| Aldh1a3 |
A |
G |
7: 66,061,248 (GRCm39) |
|
probably null |
Het |
| Aldh3b2 |
T |
A |
19: 4,030,705 (GRCm39) |
M390K |
probably benign |
Het |
| Arhgap45 |
T |
C |
10: 79,863,536 (GRCm39) |
I793T |
probably damaging |
Het |
| Arsb |
A |
G |
13: 93,944,067 (GRCm39) |
M253V |
probably benign |
Het |
| Atcay |
T |
C |
10: 81,048,312 (GRCm39) |
D258G |
possibly damaging |
Het |
| Atf1 |
G |
T |
15: 100,152,395 (GRCm39) |
|
probably null |
Het |
| Atp1a4 |
C |
T |
1: 172,067,731 (GRCm39) |
E511K |
probably benign |
Het |
| Atp8a1 |
A |
G |
5: 67,825,000 (GRCm39) |
V777A |
probably benign |
Het |
| Baz1a |
T |
C |
12: 54,947,122 (GRCm39) |
T1173A |
possibly damaging |
Het |
| Bdh2 |
A |
T |
3: 134,991,370 (GRCm39) |
D15V |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,576,240 (GRCm39) |
Y69C |
probably damaging |
Het |
| Caskin2 |
A |
G |
11: 115,694,440 (GRCm39) |
L387P |
probably benign |
Het |
| Cat |
T |
C |
2: 103,315,334 (GRCm39) |
E17G |
probably benign |
Het |
| Ccdc15 |
T |
C |
9: 37,259,091 (GRCm39) |
I54M |
probably benign |
Het |
| Ccn1 |
T |
C |
3: 145,353,965 (GRCm39) |
Y275C |
probably damaging |
Het |
| Cdhr1 |
T |
G |
14: 36,801,682 (GRCm39) |
I754L |
probably benign |
Het |
| Cep120 |
G |
A |
18: 53,856,313 (GRCm39) |
T368I |
probably benign |
Het |
| Cep126 |
C |
A |
9: 8,100,909 (GRCm39) |
D542Y |
probably damaging |
Het |
| Cep135 |
T |
C |
5: 76,772,594 (GRCm39) |
S660P |
possibly damaging |
Het |
| Cfap70 |
A |
T |
14: 20,470,879 (GRCm39) |
S455R |
possibly damaging |
Het |
| Chd8 |
A |
G |
14: 52,458,450 (GRCm39) |
M886T |
probably damaging |
Het |
| Ckap5 |
T |
C |
2: 91,416,688 (GRCm39) |
S1098P |
probably benign |
Het |
| Clec4e |
A |
T |
6: 123,260,533 (GRCm39) |
I204N |
probably damaging |
Het |
| Cntnap5c |
G |
A |
17: 58,666,291 (GRCm39) |
R1107H |
probably damaging |
Het |
| Cramp1 |
T |
C |
17: 25,183,913 (GRCm39) |
D1234G |
probably damaging |
Het |
| Csf1r |
A |
T |
18: 61,245,867 (GRCm39) |
I275L |
probably benign |
Het |
| Cyp27a1 |
A |
G |
1: 74,776,435 (GRCm39) |
E457G |
probably benign |
Het |
| Cyp2d11 |
T |
C |
15: 82,273,749 (GRCm39) |
T410A |
probably benign |
Het |
| Cyp2d22 |
G |
C |
15: 82,257,373 (GRCm39) |
T264S |
probably benign |
Het |
| Daam2 |
G |
A |
17: 49,790,088 (GRCm39) |
R390W |
probably damaging |
Het |
| Decr2 |
T |
C |
17: 26,302,053 (GRCm39) |
S226G |
probably benign |
Het |
| Dennd6b |
T |
C |
15: 89,074,544 (GRCm39) |
D91G |
possibly damaging |
Het |
| Dglucy |
T |
C |
12: 100,825,903 (GRCm39) |
V515A |
possibly damaging |
Het |
| Dlg5 |
A |
T |
14: 24,214,187 (GRCm39) |
L734* |
probably null |
Het |
| Exoc5 |
A |
G |
14: 49,272,347 (GRCm39) |
Y356H |
probably benign |
Het |
| Fut7 |
T |
A |
2: 25,315,738 (GRCm39) |
V332D |
probably benign |
Het |
| Gnas |
T |
C |
2: 174,140,526 (GRCm39) |
S232P |
probably damaging |
Het |
| Gramd4 |
A |
G |
15: 86,017,106 (GRCm39) |
E522G |
probably damaging |
Het |
| Gys1 |
A |
G |
7: 45,092,970 (GRCm39) |
T297A |
probably damaging |
Het |
| Herc4 |
T |
C |
10: 63,109,304 (GRCm39) |
S180P |
probably benign |
Het |
| Hivep3 |
C |
T |
4: 119,953,435 (GRCm39) |
P584S |
possibly damaging |
Het |
| Irag2 |
T |
A |
6: 145,115,499 (GRCm39) |
S310T |
probably damaging |
Het |
| Itpk1 |
G |
T |
12: 102,641,729 (GRCm39) |
|
probably null |
Het |
| Jmjd1c |
A |
T |
10: 67,061,219 (GRCm39) |
S1191C |
probably damaging |
Het |
| Lima1 |
T |
C |
15: 99,717,565 (GRCm39) |
N147S |
probably benign |
Het |
| Map4k5 |
G |
A |
12: 69,865,266 (GRCm39) |
T506I |
probably damaging |
Het |
| Mat1a |
A |
T |
14: 40,832,991 (GRCm39) |
E58V |
probably damaging |
Het |
| Mfsd13a |
T |
C |
19: 46,360,492 (GRCm39) |
L348P |
probably damaging |
Het |
| Mon2 |
A |
G |
10: 122,845,470 (GRCm39) |
Y1413H |
probably damaging |
Het |
| Mpp3 |
C |
A |
11: 101,909,378 (GRCm39) |
|
probably benign |
Het |
| Mpp4 |
T |
A |
1: 59,183,961 (GRCm39) |
I260F |
probably damaging |
Het |
| Myocd |
C |
A |
11: 65,091,733 (GRCm39) |
G70C |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,348,286 (GRCm39) |
S889N |
probably benign |
Het |
| Nckap5 |
T |
A |
1: 125,942,367 (GRCm39) |
D209V |
probably damaging |
Het |
| Nlrp9a |
A |
G |
7: 26,264,366 (GRCm39) |
K707R |
probably benign |
Het |
| Npr3 |
A |
G |
15: 11,905,055 (GRCm39) |
L224S |
probably benign |
Het |
| Or5m9b |
T |
A |
2: 85,905,549 (GRCm39) |
L155Q |
probably damaging |
Het |
| Or5w20 |
T |
A |
2: 87,727,383 (GRCm39) |
V280E |
probably damaging |
Het |
| Or6c74 |
A |
G |
10: 129,869,602 (GRCm39) |
S36G |
probably damaging |
Het |
| Otof |
C |
T |
5: 30,545,998 (GRCm39) |
D467N |
probably damaging |
Het |
| Paxx |
T |
C |
2: 25,350,640 (GRCm39) |
|
probably benign |
Het |
| Pcmt1 |
G |
A |
10: 7,516,474 (GRCm39) |
R179* |
probably null |
Het |
| Phkb |
T |
A |
8: 86,697,580 (GRCm39) |
V463D |
probably benign |
Het |
| Prkcq |
T |
C |
2: 11,250,208 (GRCm39) |
V175A |
probably damaging |
Het |
| Rasl11b |
T |
G |
5: 74,356,797 (GRCm39) |
I58S |
probably damaging |
Het |
| Rb1cc1 |
A |
T |
1: 6,318,419 (GRCm39) |
|
probably null |
Het |
| Reck |
T |
A |
4: 43,913,771 (GRCm39) |
|
probably null |
Het |
| Riox1 |
G |
T |
12: 83,998,156 (GRCm39) |
D231Y |
probably damaging |
Het |
| Rlf |
T |
A |
4: 121,005,617 (GRCm39) |
N1231I |
probably damaging |
Het |
| Rpn1 |
A |
G |
6: 88,072,530 (GRCm39) |
D291G |
possibly damaging |
Het |
| Samsn1 |
C |
T |
16: 75,742,461 (GRCm39) |
|
noncoding transcript |
Het |
| Scara5 |
T |
C |
14: 65,927,249 (GRCm39) |
C49R |
possibly damaging |
Het |
| Serpini1 |
A |
G |
3: 75,521,785 (GRCm39) |
D92G |
probably benign |
Het |
| Setdb2 |
A |
T |
14: 59,656,858 (GRCm39) |
L153Q |
probably damaging |
Het |
| Sh3rf3 |
C |
T |
10: 58,649,809 (GRCm39) |
T138M |
probably benign |
Het |
| Shkbp1 |
C |
T |
7: 27,054,825 (GRCm39) |
|
probably null |
Het |
| Slc22a29 |
G |
A |
19: 8,195,707 (GRCm39) |
P111S |
probably benign |
Het |
| Smarca1 |
A |
G |
X: 46,941,564 (GRCm39) |
V618A |
probably damaging |
Het |
| Spef2 |
T |
A |
15: 9,609,602 (GRCm39) |
M1308L |
probably damaging |
Het |
| Spink5 |
A |
G |
18: 44,123,775 (GRCm39) |
N354S |
probably benign |
Het |
| Srrm2 |
T |
C |
17: 24,040,465 (GRCm39) |
S2370P |
probably damaging |
Het |
| Ssxb3 |
A |
T |
X: 8,454,905 (GRCm39) |
I28N |
probably damaging |
Het |
| Sucla2 |
A |
G |
14: 73,831,119 (GRCm39) |
T411A |
probably damaging |
Het |
| Tex38 |
A |
C |
4: 115,637,537 (GRCm39) |
S89A |
probably benign |
Het |
| Tjp2 |
A |
T |
19: 24,088,437 (GRCm39) |
D723E |
probably damaging |
Het |
| Tln2 |
A |
T |
9: 67,163,183 (GRCm39) |
N1121K |
probably damaging |
Het |
| Tti1 |
T |
C |
2: 157,850,966 (GRCm39) |
E91G |
possibly damaging |
Het |
| Wbp2 |
A |
T |
11: 115,973,191 (GRCm39) |
M72K |
possibly damaging |
Het |
| Wdfy4 |
C |
A |
14: 32,828,001 (GRCm39) |
C1062F |
possibly damaging |
Het |
| Wiz |
A |
G |
17: 32,578,346 (GRCm39) |
Y389H |
probably damaging |
Het |
| Zcchc3 |
T |
C |
2: 152,256,012 (GRCm39) |
K229R |
probably damaging |
Het |
| Zmat3 |
C |
A |
3: 32,415,131 (GRCm39) |
D60Y |
probably damaging |
Het |
|
| Other mutations in Dop1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dop1b
|
APN |
16 |
93,596,914 (GRCm39) |
unclassified |
probably benign |
|
|
IGL00492:Dop1b
|
APN |
16 |
93,577,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00753:Dop1b
|
APN |
16 |
93,566,512 (GRCm39) |
missense |
probably benign |
|
|
IGL00832:Dop1b
|
APN |
16 |
93,560,289 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00939:Dop1b
|
APN |
16 |
93,570,971 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL01019:Dop1b
|
APN |
16 |
93,607,117 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01288:Dop1b
|
APN |
16 |
93,536,181 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01505:Dop1b
|
APN |
16 |
93,554,004 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01535:Dop1b
|
APN |
16 |
93,566,846 (GRCm39) |
nonsense |
probably null |
|
|
IGL01696:Dop1b
|
APN |
16 |
93,567,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02077:Dop1b
|
APN |
16 |
93,577,648 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02163:Dop1b
|
APN |
16 |
93,559,315 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02234:Dop1b
|
APN |
16 |
93,549,039 (GRCm39) |
missense |
probably benign |
|
|
IGL02302:Dop1b
|
APN |
16 |
93,607,005 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL02485:Dop1b
|
APN |
16 |
93,567,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02563:Dop1b
|
APN |
16 |
93,574,293 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02733:Dop1b
|
APN |
16 |
93,536,079 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02792:Dop1b
|
APN |
16 |
93,598,460 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL02941:Dop1b
|
APN |
16 |
93,552,361 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03143:Dop1b
|
APN |
16 |
93,556,543 (GRCm39) |
missense |
probably benign |
|
|
PIT4519001:Dop1b
|
UTSW |
16 |
93,558,942 (GRCm39) |
missense |
probably benign |
|
|
R0320:Dop1b
|
UTSW |
16 |
93,607,035 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0499:Dop1b
|
UTSW |
16 |
93,567,325 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0501:Dop1b
|
UTSW |
16 |
93,549,750 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0534:Dop1b
|
UTSW |
16 |
93,559,393 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0583:Dop1b
|
UTSW |
16 |
93,552,374 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0626:Dop1b
|
UTSW |
16 |
93,560,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0724:Dop1b
|
UTSW |
16 |
93,559,213 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0907:Dop1b
|
UTSW |
16 |
93,598,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1263:Dop1b
|
UTSW |
16 |
93,574,274 (GRCm39) |
missense |
probably benign |
|
|
R1378:Dop1b
|
UTSW |
16 |
93,567,280 (GRCm39) |
missense |
probably benign |
|
|
R1572:Dop1b
|
UTSW |
16 |
93,567,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1604:Dop1b
|
UTSW |
16 |
93,559,458 (GRCm39) |
missense |
probably benign |
|
|
R1642:Dop1b
|
UTSW |
16 |
93,559,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1668:Dop1b
|
UTSW |
16 |
93,562,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1669:Dop1b
|
UTSW |
16 |
93,566,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1702:Dop1b
|
UTSW |
16 |
93,544,509 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1711:Dop1b
|
UTSW |
16 |
93,596,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Dop1b
|
UTSW |
16 |
93,513,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1988:Dop1b
|
UTSW |
16 |
93,563,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2029:Dop1b
|
UTSW |
16 |
93,566,323 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2139:Dop1b
|
UTSW |
16 |
93,567,895 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2355:Dop1b
|
UTSW |
16 |
93,567,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3609:Dop1b
|
UTSW |
16 |
93,536,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3792:Dop1b
|
UTSW |
16 |
93,568,734 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R4364:Dop1b
|
UTSW |
16 |
93,567,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4380:Dop1b
|
UTSW |
16 |
93,513,120 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4455:Dop1b
|
UTSW |
16 |
93,563,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4779:Dop1b
|
UTSW |
16 |
93,553,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4820:Dop1b
|
UTSW |
16 |
93,589,978 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4834:Dop1b
|
UTSW |
16 |
93,536,892 (GRCm39) |
start codon destroyed |
probably null |
0.70 |
|
R4866:Dop1b
|
UTSW |
16 |
93,560,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4882:Dop1b
|
UTSW |
16 |
93,549,802 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4900:Dop1b
|
UTSW |
16 |
93,560,318 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5153:Dop1b
|
UTSW |
16 |
93,570,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5176:Dop1b
|
UTSW |
16 |
93,536,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5206:Dop1b
|
UTSW |
16 |
93,598,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5320:Dop1b
|
UTSW |
16 |
93,536,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5361:Dop1b
|
UTSW |
16 |
93,567,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5380:Dop1b
|
UTSW |
16 |
93,560,298 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5476:Dop1b
|
UTSW |
16 |
93,570,801 (GRCm39) |
splice site |
probably null |
|
|
R5502:Dop1b
|
UTSW |
16 |
93,590,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5543:Dop1b
|
UTSW |
16 |
93,595,808 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5557:Dop1b
|
UTSW |
16 |
93,560,819 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5901:Dop1b
|
UTSW |
16 |
93,566,639 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5907:Dop1b
|
UTSW |
16 |
93,598,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6174:Dop1b
|
UTSW |
16 |
93,563,110 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6256:Dop1b
|
UTSW |
16 |
93,604,102 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6383:Dop1b
|
UTSW |
16 |
93,579,136 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6525:Dop1b
|
UTSW |
16 |
93,606,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6554:Dop1b
|
UTSW |
16 |
93,557,346 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6823:Dop1b
|
UTSW |
16 |
93,552,373 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7036:Dop1b
|
UTSW |
16 |
93,574,378 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7058:Dop1b
|
UTSW |
16 |
93,573,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7061:Dop1b
|
UTSW |
16 |
93,558,951 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7209:Dop1b
|
UTSW |
16 |
93,566,733 (GRCm39) |
missense |
probably benign |
|
|
R7214:Dop1b
|
UTSW |
16 |
93,607,023 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7232:Dop1b
|
UTSW |
16 |
93,557,373 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7255:Dop1b
|
UTSW |
16 |
93,567,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7335:Dop1b
|
UTSW |
16 |
93,544,396 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7535:Dop1b
|
UTSW |
16 |
93,603,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7700:Dop1b
|
UTSW |
16 |
93,595,649 (GRCm39) |
splice site |
probably null |
|
|
R7763:Dop1b
|
UTSW |
16 |
93,552,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7814:Dop1b
|
UTSW |
16 |
93,596,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7839:Dop1b
|
UTSW |
16 |
93,560,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7862:Dop1b
|
UTSW |
16 |
93,546,851 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7894:Dop1b
|
UTSW |
16 |
93,607,092 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7952:Dop1b
|
UTSW |
16 |
93,546,848 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7956:Dop1b
|
UTSW |
16 |
93,567,916 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8033:Dop1b
|
UTSW |
16 |
93,566,371 (GRCm39) |
missense |
probably benign |
|
|
R8061:Dop1b
|
UTSW |
16 |
93,546,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8067:Dop1b
|
UTSW |
16 |
93,562,336 (GRCm39) |
nonsense |
probably null |
|
|
R8146:Dop1b
|
UTSW |
16 |
93,546,827 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8184:Dop1b
|
UTSW |
16 |
93,573,881 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8221:Dop1b
|
UTSW |
16 |
93,546,847 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8263:Dop1b
|
UTSW |
16 |
93,559,083 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8329:Dop1b
|
UTSW |
16 |
93,568,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8555:Dop1b
|
UTSW |
16 |
93,568,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8683:Dop1b
|
UTSW |
16 |
93,570,809 (GRCm39) |
missense |
probably benign |
|
|
R8683:Dop1b
|
UTSW |
16 |
93,568,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8716:Dop1b
|
UTSW |
16 |
93,577,673 (GRCm39) |
nonsense |
probably null |
|
|
R8807:Dop1b
|
UTSW |
16 |
93,558,973 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8840:Dop1b
|
UTSW |
16 |
93,607,005 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8851:Dop1b
|
UTSW |
16 |
93,559,398 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8884:Dop1b
|
UTSW |
16 |
93,556,550 (GRCm39) |
missense |
probably benign |
|
|
R8976:Dop1b
|
UTSW |
16 |
93,558,969 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9219:Dop1b
|
UTSW |
16 |
93,567,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9238:Dop1b
|
UTSW |
16 |
93,546,018 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9284:Dop1b
|
UTSW |
16 |
93,557,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9289:Dop1b
|
UTSW |
16 |
93,568,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9298:Dop1b
|
UTSW |
16 |
93,597,087 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9338:Dop1b
|
UTSW |
16 |
93,600,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9346:Dop1b
|
UTSW |
16 |
93,577,702 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9444:Dop1b
|
UTSW |
16 |
93,607,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9500:Dop1b
|
UTSW |
16 |
93,607,171 (GRCm39) |
missense |
probably benign |
|
|
R9601:Dop1b
|
UTSW |
16 |
93,544,531 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9793:Dop1b
|
UTSW |
16 |
93,598,503 (GRCm39) |
missense |
probably benign |
0.30 |
|
Z1088:Dop1b
|
UTSW |
16 |
93,560,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,604,756 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,600,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dop1b
|
UTSW |
16 |
93,566,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dop1b
|
UTSW |
16 |
93,560,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGACTGTCCATACCAGACCTG -3'
(R):5'- AAGAGGCTTAGAACCCAGGC -3'
Sequencing Primer
(F):5'- GTCCATACCAGACCTGCAGGAG -3'
(R):5'- CCAGGCAAAGCTAAGATGCAGTTC -3'
|
| Posted On |
2014-08-25 |
Incidental Mutation