Mutagenetix > Incidental Mutation

Incidental Mutation 'R7823:Myo9a'

602011

Institutional Source

Beutler Lab

Gene Symbol

Myo9a

Ensembl Gene

ENSMUSG00000039585

Gene Name

myosin IXa

Synonyms

C130068I12Rik, 4732465J09Rik

MMRRC Submission

045877-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7823 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

59658179-59836149 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 59719233 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Isoleucine at position 507 (F507I)

Ref Sequence

ENSEMBL: ENSMUSP00000122852 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000128341] [ENSMUST00000135298] [ENSMUST00000136740]

AlphaFold

Q8C170

Predicted Effect

probably damaging
Transcript: ENSMUST00000128341
AA Change: F507I

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000119401
Gene: ENSMUSG00000039585
AA Change: F507I

Domain	Start	End	E-Value	Type
RA	14	112	5.57e-30	SMART
low complexity region	129	137	N/A	INTRINSIC
MYSc	140	1018	N/A	SMART
IQ	1019	1041	1.79e1	SMART
IQ	1042	1064	4.11e0	SMART
IQ	1074	1096	1.9e-2	SMART
IQ	1115	1137	1.01e-6	SMART
IQ	1138	1160	8.71e-2	SMART
low complexity region	1161	1173	N/A	INTRINSIC
coiled coil region	1265	1285	N/A	INTRINSIC
low complexity region	1372	1384	N/A	INTRINSIC
coiled coil region	1492	1539	N/A	INTRINSIC
Blast:MYSc	1685	1938	6e-89	BLAST
low complexity region	1982	1993	N/A	INTRINSIC
C1	2002	2050	2.6e-9	SMART
RhoGAP	2075	2250	3.36e-73	SMART
coiled coil region	2320	2360	N/A	INTRINSIC
low complexity region	2419	2438	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000135298
AA Change: F507I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000117432
Gene: ENSMUSG00000039585
AA Change: F507I

Domain	Start	End	E-Value	Type
RA	14	112	5.57e-30	SMART
low complexity region	129	137	N/A	INTRINSIC
MYSc	140	1018	N/A	SMART
IQ	1019	1041	1.79e1	SMART
IQ	1042	1064	4.11e0	SMART
IQ	1074	1096	1.9e-2	SMART
IQ	1115	1137	1.01e-6	SMART
IQ	1138	1160	8.71e-2	SMART
low complexity region	1161	1173	N/A	INTRINSIC
coiled coil region	1265	1285	N/A	INTRINSIC
low complexity region	1372	1384	N/A	INTRINSIC
coiled coil region	1492	1539	N/A	INTRINSIC
low complexity region	1744	1759	N/A	INTRINSIC
low complexity region	2053	2064	N/A	INTRINSIC
C1	2073	2121	2.6e-9	SMART
RhoGAP	2146	2321	3.36e-73	SMART
coiled coil region	2391	2431	N/A	INTRINSIC
low complexity region	2490	2509	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000136740
AA Change: F507I

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000122852
Gene: ENSMUSG00000039585
AA Change: F507I

Domain	Start	End	E-Value	Type
RA	14	112	5.57e-30	SMART
low complexity region	129	137	N/A	INTRINSIC
MYSc	140	1018	N/A	SMART
IQ	1019	1041	1.79e1	SMART
IQ	1042	1064	4.11e0	SMART
IQ	1074	1096	1.9e-2	SMART
IQ	1115	1137	1.01e-6	SMART
IQ	1138	1160	8.71e-2	SMART
low complexity region	1161	1173	N/A	INTRINSIC
coiled coil region	1265	1285	N/A	INTRINSIC
low complexity region	1372	1384	N/A	INTRINSIC
coiled coil region	1492	1539	N/A	INTRINSIC
low complexity region	1744	1759	N/A	INTRINSIC
low complexity region	2053	2064	N/A	INTRINSIC
C1	2073	2121	2.6e-9	SMART
RhoGAP	2146	2321	3.36e-73	SMART
coiled coil region	2409	2449	N/A	INTRINSIC
low complexity region	2508	2527	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

99% (68/69)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous KO leads to obstructive hydrocephaly caused by blockage of the third ventricle and the rostral aqueduct caused by developmental failures of their ependymal cells. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc4	A	G	14: 118,771,484 (GRCm39)	V869A	probably benign	Het
Alox15	C	A	11: 70,235,494 (GRCm39)	V623L	possibly damaging	Het
Angpt4	T	G	2: 151,753,286 (GRCm39)	L12R	unknown	Het
Cdh24	C	T	14: 54,874,875 (GRCm39)	A42T	probably damaging	Het
Cep250	T	A	2: 155,807,336 (GRCm39)	S234T	possibly damaging	Het
Clnk	T	A	5: 38,907,694 (GRCm39)	Y188F	probably benign	Het
Csmd2	A	T	4: 128,103,698 (GRCm39)	T306S		Het
Cyp2f2	G	A	7: 26,828,678 (GRCm39)	V183I	probably benign	Het
Dgka	T	A	10: 128,572,135 (GRCm39)	Y50F	probably benign	Het
Dgkh	C	T	14: 78,841,921 (GRCm39)	V434I	probably benign	Het
Epb41	A	G	4: 131,701,993 (GRCm39)		probably null	Het
Fam220a	A	G	5: 143,549,011 (GRCm39)	D141G	probably damaging	Het
Fbxo11	A	G	17: 88,300,610 (GRCm39)	L807S	probably damaging	Het
G530012D18Rik	G	C	1: 85,504,923 (GRCm39)		probably benign	Het
Ggt1	G	A	10: 75,410,175 (GRCm39)	V36M	possibly damaging	Het
Gjb2	T	C	14: 57,337,963 (GRCm39)	I82V	probably benign	Het
Gm7579	T	A	7: 141,766,307 (GRCm39)	C238S	unknown	Het
Hps1	G	A	19: 42,744,146 (GRCm39)	T681M	possibly damaging	Het
Iqck	T	C	7: 118,472,046 (GRCm39)	Y64H	probably damaging	Het
Ldlr	G	A	9: 21,653,602 (GRCm39)		probably null	Het
Macc1	A	C	12: 119,410,800 (GRCm39)	K523Q	probably damaging	Het
Mon2	A	T	10: 122,868,559 (GRCm39)	I498N	probably damaging	Het
Mphosph9	T	C	5: 124,442,319 (GRCm39)	E373G	probably damaging	Het
Mthfr	T	C	4: 148,135,944 (GRCm39)	I314T	probably benign	Het
Mtmr4	T	G	11: 87,503,015 (GRCm39)	I1023S	probably damaging	Het
Nlrp10	T	A	7: 108,523,468 (GRCm39)	M671L	probably benign	Het
Nt5c1a	T	C	4: 123,102,365 (GRCm39)	V97A	probably damaging	Het
Nxpe5	A	G	5: 138,237,844 (GRCm39)	R123G	possibly damaging	Het
Obscn	T	C	11: 58,998,766 (GRCm39)	S1369G	probably damaging	Het
Oga	A	G	19: 45,765,354 (GRCm39)	V151A	possibly damaging	Het
Or4a75	A	G	2: 89,447,613 (GRCm39)	*308Q	probably null	Het
Or52m2	A	G	7: 102,264,164 (GRCm39)	S11P	probably benign	Het
Or5b99	A	T	19: 12,976,781 (GRCm39)	I144F	probably damaging	Het
Or6c33	T	A	10: 129,854,136 (GRCm39)	M302K	probably benign	Het
Or6k2	A	G	1: 173,987,254 (GRCm39)	K305R	probably benign	Het
Or8b57	A	T	9: 40,003,644 (GRCm39)	V202E	probably damaging	Het
Pak6	G	A	2: 118,525,793 (GRCm39)	A618T	probably benign	Het
Pax7	T	A	4: 139,468,150 (GRCm39)	E489V	probably benign	Het
Phactr4	G	A	4: 132,088,930 (GRCm39)	R651*	probably null	Het
Pik3c2b	C	T	1: 133,030,043 (GRCm39)	R1435C	probably damaging	Het
Pla2g4c	A	T	7: 13,063,944 (GRCm39)	I68F	probably damaging	Het
Plppr1	A	G	4: 49,325,703 (GRCm39)	M300V	probably benign	Het
Ptgfrn	C	T	3: 100,950,725 (GRCm39)	V863I	probably damaging	Het
Rabep2	T	C	7: 126,037,893 (GRCm39)	S222P	probably damaging	Het
Ramacl	A	G	13: 67,055,351 (GRCm39)		probably benign	Het
Rbm20	A	T	19: 53,831,785 (GRCm39)	D673V	probably benign	Het
Rsf1	GCG	GCGACGGCGACG	7: 97,229,114 (GRCm39)		probably benign	Het
Scn4a	C	A	11: 106,233,334 (GRCm39)	A413S	probably damaging	Het
Scn9a	A	T	2: 66,314,135 (GRCm39)	M1850K	probably damaging	Het
Sh3tc2	T	A	18: 62,086,188 (GRCm39)	M1K	probably null	Het
Slc22a28	G	A	19: 8,041,890 (GRCm39)	T439I	probably benign	Het
Slc25a36	A	G	9: 96,966,444 (GRCm39)		probably null	Het
Smpd3	A	C	8: 106,982,254 (GRCm39)	C617G	probably benign	Het
Spata3	T	C	1: 85,949,781 (GRCm39)		probably benign	Het
Srp68	C	T	11: 116,156,265 (GRCm39)	R159Q	probably damaging	Het
Ssbp2	C	A	13: 91,790,448 (GRCm39)	L104I	possibly damaging	Het
St8sia3	T	A	18: 64,400,027 (GRCm39)	F7L	probably benign	Het
Stard9	T	C	2: 120,532,587 (GRCm39)	V2948A	probably damaging	Het
Syne4	A	G	7: 30,018,280 (GRCm39)	T341A	probably benign	Het
Tcf7l2	T	A	19: 55,731,521 (GRCm39)	D91E	possibly damaging	Het
Tekt5	T	A	16: 10,203,943 (GRCm39)	I236F	probably damaging	Het
Tlk2	T	C	11: 105,144,133 (GRCm39)	Y316H	probably damaging	Het
Tmem184b	C	T	15: 79,249,491 (GRCm39)	A326T	probably benign	Het
Tnks2	G	A	19: 36,829,954 (GRCm39)		probably null	Het
Trpc4	C	A	3: 54,209,640 (GRCm39)	Y668*	probably null	Het
Ttc9c	A	T	19: 8,793,286 (GRCm39)	F118Y	probably benign	Het
Ulk1	C	T	5: 110,946,780 (GRCm39)	C95Y	probably damaging	Het
Vars2	A	C	17: 35,970,028 (GRCm39)	L787R	probably damaging	Het
Vwa3a	T	C	7: 120,372,185 (GRCm39)	S254P	probably damaging	Het
Wdr81	T	C	11: 75,340,627 (GRCm39)	Y1250C	probably damaging	Het
Xirp2	A	T	2: 67,342,118 (GRCm39)	D1453V	probably damaging	Het
Zbtb38	A	T	9: 96,568,029 (GRCm39)	C1018*	probably null	Het
Zfp622	C	T	15: 25,984,709 (GRCm39)	T25M	probably damaging	Het

Other mutations in Myo9a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00427:Myo9a	APN	9	59,750,342 (GRCm39)	splice site	probably benign
IGL00510:Myo9a	APN	9	59,739,464 (GRCm39)	splice site	probably benign
IGL00710:Myo9a	APN	9	59,782,594 (GRCm39)	missense	probably damaging	1.00
IGL00963:Myo9a	APN	9	59,807,655 (GRCm39)	missense	probably damaging	0.98
IGL01087:Myo9a	APN	9	59,697,361 (GRCm39)	missense	possibly damaging	0.93
IGL01145:Myo9a	APN	9	59,762,658 (GRCm39)	missense	probably benign	0.18
IGL01403:Myo9a	APN	9	59,778,846 (GRCm39)	missense	probably damaging	0.98
IGL01528:Myo9a	APN	9	59,686,957 (GRCm39)	missense	probably damaging	1.00
IGL01608:Myo9a	APN	9	59,778,119 (GRCm39)	nonsense	probably null
IGL01701:Myo9a	APN	9	59,791,877 (GRCm39)	critical splice donor site	probably null
IGL01918:Myo9a	APN	9	59,686,985 (GRCm39)	missense	probably damaging	1.00
IGL02026:Myo9a	APN	9	59,813,245 (GRCm39)	missense	probably damaging	0.99
IGL02139:Myo9a	APN	9	59,687,275 (GRCm39)	missense	probably benign	0.07
IGL02176:Myo9a	APN	9	59,777,836 (GRCm39)	missense	probably benign	0.45
IGL02272:Myo9a	APN	9	59,791,883 (GRCm39)	splice site	probably benign
IGL02283:Myo9a	APN	9	59,778,956 (GRCm39)	missense	probably benign	0.00
IGL02499:Myo9a	APN	9	59,722,669 (GRCm39)	splice site	probably benign
IGL02652:Myo9a	APN	9	59,771,211 (GRCm39)	missense	probably damaging	1.00
IGL02666:Myo9a	APN	9	59,832,187 (GRCm39)	missense	probably benign	0.02
IGL02878:Myo9a	APN	9	59,815,583 (GRCm39)	critical splice donor site	probably null
IGL02982:Myo9a	APN	9	59,815,491 (GRCm39)	nonsense	probably null
IGL03072:Myo9a	APN	9	59,716,725 (GRCm39)	missense	possibly damaging	0.83
IGL03090:Myo9a	APN	9	59,801,418 (GRCm39)	splice site	probably benign
IGL03111:Myo9a	APN	9	59,734,526 (GRCm39)	missense	probably benign	0.19
IGL03389:Myo9a	APN	9	59,776,890 (GRCm39)	missense	probably damaging	1.00
essentials	UTSW	9	59,802,149 (GRCm39)	missense	probably benign	0.09
necessities	UTSW	9	59,722,617 (GRCm39)	missense	probably damaging	1.00
PIT4402001:Myo9a	UTSW	9	59,777,719 (GRCm39)	missense	possibly damaging	0.83
R0013:Myo9a	UTSW	9	59,767,489 (GRCm39)	splice site	probably benign
R0013:Myo9a	UTSW	9	59,767,489 (GRCm39)	splice site	probably benign
R0018:Myo9a	UTSW	9	59,779,007 (GRCm39)	missense	probably benign	0.00
R0018:Myo9a	UTSW	9	59,779,007 (GRCm39)	missense	probably benign	0.00
R0329:Myo9a	UTSW	9	59,830,960 (GRCm39)	missense	probably damaging	1.00
R0423:Myo9a	UTSW	9	59,802,619 (GRCm39)	missense	probably damaging	1.00
R0521:Myo9a	UTSW	9	59,801,635 (GRCm39)	missense	probably damaging	1.00
R0607:Myo9a	UTSW	9	59,829,076 (GRCm39)	missense	probably benign	0.02
R0652:Myo9a	UTSW	9	59,779,209 (GRCm39)	missense	probably benign
R0653:Myo9a	UTSW	9	59,832,274 (GRCm39)	missense	probably damaging	1.00
R0723:Myo9a	UTSW	9	59,778,383 (GRCm39)	missense	probably benign	0.01
R0784:Myo9a	UTSW	9	59,803,828 (GRCm39)	splice site	probably benign
R0842:Myo9a	UTSW	9	59,778,350 (GRCm39)	missense	probably benign	0.02
R1055:Myo9a	UTSW	9	59,762,653 (GRCm39)	missense	probably benign	0.01
R1056:Myo9a	UTSW	9	59,739,484 (GRCm39)	missense	possibly damaging	0.64
R1195:Myo9a	UTSW	9	59,802,483 (GRCm39)	missense	probably damaging	1.00
R1195:Myo9a	UTSW	9	59,802,483 (GRCm39)	missense	probably damaging	1.00
R1195:Myo9a	UTSW	9	59,802,483 (GRCm39)	missense	probably damaging	1.00
R1615:Myo9a	UTSW	9	59,695,739 (GRCm39)	missense	possibly damaging	0.68
R1698:Myo9a	UTSW	9	59,775,464 (GRCm39)	missense	probably benign	0.05
R1715:Myo9a	UTSW	9	59,739,583 (GRCm39)	missense	probably damaging	0.99
R1981:Myo9a	UTSW	9	59,801,429 (GRCm39)	missense	probably benign
R2228:Myo9a	UTSW	9	59,801,463 (GRCm39)	missense	probably benign	0.06
R2272:Myo9a	UTSW	9	59,722,584 (GRCm39)	missense	probably damaging	1.00
R2327:Myo9a	UTSW	9	59,687,048 (GRCm39)	missense	probably benign	0.11
R2990:Myo9a	UTSW	9	59,832,172 (GRCm39)	missense	possibly damaging	0.95
R3161:Myo9a	UTSW	9	59,739,598 (GRCm39)	splice site	probably benign
R3721:Myo9a	UTSW	9	59,775,463 (GRCm39)	missense	probably benign
R3928:Myo9a	UTSW	9	59,802,566 (GRCm39)	missense	probably damaging	1.00
R4197:Myo9a	UTSW	9	59,802,149 (GRCm39)	missense	probably benign	0.09
R4212:Myo9a	UTSW	9	59,813,349 (GRCm39)	nonsense	probably null
R4610:Myo9a	UTSW	9	59,779,165 (GRCm39)	missense	probably benign
R4616:Myo9a	UTSW	9	59,728,932 (GRCm39)	missense	probably damaging	1.00
R4621:Myo9a	UTSW	9	59,778,355 (GRCm39)	missense	probably benign	0.00
R4623:Myo9a	UTSW	9	59,778,355 (GRCm39)	missense	probably benign	0.00
R4632:Myo9a	UTSW	9	59,776,947 (GRCm39)	missense	probably benign	0.00
R4657:Myo9a	UTSW	9	59,782,699 (GRCm39)	critical splice donor site	probably null
R4892:Myo9a	UTSW	9	59,731,525 (GRCm39)	missense	probably damaging	0.98
R4897:Myo9a	UTSW	9	59,803,800 (GRCm39)	missense	probably benign	0.07
R4966:Myo9a	UTSW	9	59,779,017 (GRCm39)	missense	probably benign	0.00
R4993:Myo9a	UTSW	9	59,768,755 (GRCm39)	nonsense	probably null
R5160:Myo9a	UTSW	9	59,779,085 (GRCm39)	missense	probably benign	0.24
R5233:Myo9a	UTSW	9	59,817,900 (GRCm39)	missense	probably damaging	1.00
R5271:Myo9a	UTSW	9	59,814,665 (GRCm39)	missense	probably damaging	1.00
R5308:Myo9a	UTSW	9	59,771,244 (GRCm39)	missense	probably damaging	1.00
R5367:Myo9a	UTSW	9	59,807,732 (GRCm39)	missense	probably damaging	0.96
R5432:Myo9a	UTSW	9	59,772,953 (GRCm39)	missense	possibly damaging	0.94
R5459:Myo9a	UTSW	9	59,791,803 (GRCm39)	missense	probably damaging	0.98
R5511:Myo9a	UTSW	9	59,687,495 (GRCm39)	missense	probably damaging	1.00
R5568:Myo9a	UTSW	9	59,781,911 (GRCm39)	missense	probably benign
R5573:Myo9a	UTSW	9	59,778,284 (GRCm39)	missense	probably benign
R5589:Myo9a	UTSW	9	59,802,527 (GRCm39)	nonsense	probably null
R5607:Myo9a	UTSW	9	59,771,227 (GRCm39)	missense	probably damaging	1.00
R5633:Myo9a	UTSW	9	59,775,467 (GRCm39)	missense	possibly damaging	0.60
R5885:Myo9a	UTSW	9	59,778,503 (GRCm39)	missense	probably benign
R6024:Myo9a	UTSW	9	59,762,671 (GRCm39)	missense	possibly damaging	0.68
R6086:Myo9a	UTSW	9	59,697,340 (GRCm39)	nonsense	probably null
R6146:Myo9a	UTSW	9	59,778,512 (GRCm39)	missense	probably benign	0.01
R6194:Myo9a	UTSW	9	59,777,033 (GRCm39)	missense	probably benign	0.00
R6213:Myo9a	UTSW	9	59,734,541 (GRCm39)	missense	probably damaging	1.00
R6368:Myo9a	UTSW	9	59,832,231 (GRCm39)	missense	probably benign	0.01
R6550:Myo9a	UTSW	9	59,775,482 (GRCm39)	missense	probably damaging	1.00
R6612:Myo9a	UTSW	9	59,734,479 (GRCm39)	missense	probably damaging	1.00
R6665:Myo9a	UTSW	9	59,779,155 (GRCm39)	missense	probably benign	0.09
R6951:Myo9a	UTSW	9	59,802,051 (GRCm39)	missense	probably damaging	1.00
R7026:Myo9a	UTSW	9	59,722,617 (GRCm39)	missense	probably damaging	1.00
R7107:Myo9a	UTSW	9	59,778,098 (GRCm39)	missense	probably benign	0.44
R7310:Myo9a	UTSW	9	59,778,436 (GRCm39)	missense	probably benign	0.08
R7473:Myo9a	UTSW	9	59,802,527 (GRCm39)	missense	probably benign	0.31
R7723:Myo9a	UTSW	9	59,687,141 (GRCm39)	missense	probably damaging	1.00
R7824:Myo9a	UTSW	9	59,767,392 (GRCm39)	missense	probably damaging	1.00
R7965:Myo9a	UTSW	9	59,695,721 (GRCm39)	missense	probably damaging	1.00
R8031:Myo9a	UTSW	9	59,687,374 (GRCm39)	missense	probably benign	0.33
R8055:Myo9a	UTSW	9	59,814,743 (GRCm39)	missense	probably damaging	1.00
R8071:Myo9a	UTSW	9	59,781,931 (GRCm39)	missense	probably benign
R8250:Myo9a	UTSW	9	59,767,392 (GRCm39)	missense	probably damaging	1.00
R8260:Myo9a	UTSW	9	59,817,961 (GRCm39)	missense	probably benign	0.08
R8355:Myo9a	UTSW	9	59,817,130 (GRCm39)	missense	probably damaging	1.00
R8432:Myo9a	UTSW	9	59,687,548 (GRCm39)	missense	probably damaging	1.00
R8470:Myo9a	UTSW	9	59,739,573 (GRCm39)	missense	probably damaging	1.00
R8528:Myo9a	UTSW	9	59,767,423 (GRCm39)	missense	probably damaging	1.00
R8681:Myo9a	UTSW	9	59,775,394 (GRCm39)	missense	probably benign	0.16
R8690:Myo9a	UTSW	9	59,782,657 (GRCm39)	missense	probably benign
R8793:Myo9a	UTSW	9	59,791,850 (GRCm39)	missense	probably benign	0.03
R8812:Myo9a	UTSW	9	59,687,030 (GRCm39)	missense	probably benign	0.14
R9016:Myo9a	UTSW	9	59,775,427 (GRCm39)	nonsense	probably null
R9026:Myo9a	UTSW	9	59,716,757 (GRCm39)	missense	probably damaging	0.96
R9036:Myo9a	UTSW	9	59,687,584 (GRCm39)	nonsense	probably null
R9130:Myo9a	UTSW	9	59,739,514 (GRCm39)	missense	probably damaging	0.98
R9131:Myo9a	UTSW	9	59,768,772 (GRCm39)	missense	probably damaging	1.00
R9213:Myo9a	UTSW	9	59,772,922 (GRCm39)	missense	probably benign	0.04
R9498:Myo9a	UTSW	9	59,734,466 (GRCm39)	missense	probably damaging	1.00
R9575:Myo9a	UTSW	9	59,813,190 (GRCm39)	missense	probably damaging	1.00
R9651:Myo9a	UTSW	9	59,778,764 (GRCm39)	missense	probably damaging	0.96
R9672:Myo9a	UTSW	9	59,687,332 (GRCm39)	missense	probably benign	0.16
RF018:Myo9a	UTSW	9	59,776,869 (GRCm39)	missense	probably benign	0.00
RF019:Myo9a	UTSW	9	59,829,055 (GRCm39)	missense	probably benign	0.00
Z1176:Myo9a	UTSW	9	59,802,542 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GCCAGACTGCATAGCATATGG -3'
(R):5'- GACACACAAAATGGTTAACCTGAATAG -3'

Sequencing Primer
(F):5'- CTGGGAATTGAACTCAGGACCTCTG -3'
(R):5'- GTTCAAGTACTCACCAGTTT -3'

Posted On

2019-12-03