Incidental Mutation 'R8944:Sphkap'
| ID |
681131 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sphkap
|
| Ensembl Gene |
ENSMUSG00000026163 |
| Gene Name |
SPHK1 interactor, AKAP domain containing |
| Synonyms |
SKIP, A930009L15Rik, 4930544G21Rik |
| MMRRC Submission |
068783-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.079)
|
| Stock # |
R8944 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
83233163-83385853 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 83256927 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 274
(H274L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124872
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159078]
[ENSMUST00000160953]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159078
|
| SMART Domains |
Protein: ENSMUSP00000124384
Gene: ENSMUSG00000026163
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
303 |
314 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
382 |
462 |
5e-3 |
SMART |
|
low complexity region
|
809 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1221 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1254 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1281 |
1398 |
7.5e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160953
AA Change: H274L
PolyPhen 2
Score 0.387 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000124872
Gene: ENSMUSG00000026163
AA Change: H274L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
590 |
601 |
N/A |
INTRINSIC |
|
SCOP:d1ash__
|
669 |
749 |
6e-3 |
SMART |
|
low complexity region
|
1096 |
1106 |
N/A |
INTRINSIC |
|
low complexity region
|
1141 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1508 |
N/A |
INTRINSIC |
|
Pfam:AKAP_110
|
1540 |
1655 |
6.4e-12 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (88/88) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
A |
T |
11: 72,049,851 (GRCm39) |
|
probably benign |
Het |
| A830018L16Rik |
A |
T |
1: 11,484,706 (GRCm39) |
|
probably benign |
Het |
| Acox1 |
C |
T |
11: 116,066,040 (GRCm39) |
R454H |
probably damaging |
Het |
| Acte1 |
G |
T |
7: 143,434,902 (GRCm39) |
|
probably null |
Het |
| Adam18 |
A |
G |
8: 25,164,703 (GRCm39) |
L4P |
probably damaging |
Het |
| AI182371 |
A |
C |
2: 34,990,622 (GRCm39) |
L25R |
probably damaging |
Het |
| Ankrd12 |
A |
C |
17: 66,277,195 (GRCm39) |
Y2026* |
probably null |
Het |
| Atad5 |
C |
T |
11: 79,986,524 (GRCm39) |
T537M |
possibly damaging |
Het |
| Atosa |
A |
G |
9: 74,911,562 (GRCm39) |
Y11C |
probably damaging |
Het |
| Avil |
G |
T |
10: 126,846,455 (GRCm39) |
G420V |
probably damaging |
Het |
| Bche |
A |
T |
3: 73,608,008 (GRCm39) |
F473I |
probably damaging |
Het |
| Borcs5 |
T |
C |
6: 134,621,437 (GRCm39) |
|
probably null |
Het |
| C4b |
T |
C |
17: 34,961,913 (GRCm39) |
Q111R |
probably benign |
Het |
| Carmil2 |
T |
A |
8: 106,417,437 (GRCm39) |
I565N |
probably damaging |
Het |
| Cd74 |
T |
C |
18: 60,943,127 (GRCm39) |
M155T |
probably damaging |
Het |
| Chrnd |
G |
T |
1: 87,119,997 (GRCm39) |
R105L |
probably damaging |
Het |
| Clpp |
G |
T |
17: 57,300,553 (GRCm39) |
E217* |
probably null |
Het |
| Cpq |
T |
A |
15: 33,594,269 (GRCm39) |
Y427N |
probably damaging |
Het |
| Crxos |
G |
A |
7: 15,636,900 (GRCm39) |
E54K |
possibly damaging |
Het |
| Dcaf13 |
A |
G |
15: 39,001,612 (GRCm39) |
R307G |
possibly damaging |
Het |
| Ddx55 |
A |
G |
5: 124,706,788 (GRCm39) |
D595G |
probably damaging |
Het |
| Dld |
T |
A |
12: 31,390,868 (GRCm39) |
I193F |
possibly damaging |
Het |
| Dnah11 |
T |
G |
12: 118,091,381 (GRCm39) |
E917A |
possibly damaging |
Het |
| Dnai2 |
T |
A |
11: 114,641,302 (GRCm39) |
Y376N |
possibly damaging |
Het |
| Dock7 |
A |
G |
4: 98,829,243 (GRCm39) |
Y2078H |
probably damaging |
Het |
| Dusp4 |
A |
T |
8: 35,274,941 (GRCm39) |
N20I |
probably benign |
Het |
| Dzank1 |
A |
G |
2: 144,333,729 (GRCm39) |
L367P |
probably benign |
Het |
| Eea1 |
T |
A |
10: 95,832,822 (GRCm39) |
D222E |
probably damaging |
Het |
| Erich3 |
G |
C |
3: 154,462,692 (GRCm39) |
R742S |
|
Het |
| Erich6 |
C |
T |
3: 58,537,275 (GRCm39) |
M246I |
probably benign |
Het |
| Galnt16 |
T |
G |
12: 80,623,314 (GRCm39) |
I158S |
probably damaging |
Het |
| Gm28363 |
A |
G |
1: 117,655,080 (GRCm39) |
T100A |
possibly damaging |
Het |
| Gm8257 |
A |
T |
14: 44,893,849 (GRCm39) |
Y36N |
probably damaging |
Het |
| Gmpr2 |
T |
C |
14: 55,913,149 (GRCm39) |
V142A |
possibly damaging |
Het |
| Grid2ip |
T |
C |
5: 143,366,260 (GRCm39) |
|
probably null |
Het |
| Hamp2 |
A |
G |
7: 30,622,001 (GRCm39) |
F63L |
possibly damaging |
Het |
| Hmga2 |
T |
C |
10: 120,309,159 (GRCm39) |
K66E |
probably damaging |
Het |
| Hspa1a |
T |
C |
17: 35,190,019 (GRCm39) |
T295A |
probably benign |
Het |
| Ift74 |
G |
A |
4: 94,510,128 (GRCm39) |
G53D |
probably damaging |
Het |
| Ighv6-7 |
T |
C |
12: 114,419,703 (GRCm39) |
M1V |
probably null |
Het |
| Ints4 |
T |
A |
7: 97,183,593 (GRCm39) |
D769E |
probably benign |
Het |
| Kif7 |
G |
A |
7: 79,360,005 (GRCm39) |
R411C |
probably damaging |
Het |
| Klhl30 |
T |
A |
1: 91,287,174 (GRCm39) |
Y487N |
probably damaging |
Het |
| Kras |
T |
C |
6: 145,170,853 (GRCm39) |
E174G |
probably benign |
Het |
| Krt84 |
T |
C |
15: 101,437,183 (GRCm39) |
I327V |
probably benign |
Het |
| Lamb3 |
T |
A |
1: 193,014,525 (GRCm39) |
C561* |
probably null |
Het |
| Lmbrd1 |
A |
G |
1: 24,767,407 (GRCm39) |
|
probably benign |
Het |
| Lmnb1 |
T |
A |
18: 56,876,331 (GRCm39) |
S480T |
probably benign |
Het |
| Lrp2 |
C |
T |
2: 69,341,348 (GRCm39) |
G944D |
probably damaging |
Het |
| Mta3 |
G |
A |
17: 84,083,146 (GRCm39) |
E280K |
probably damaging |
Het |
| Muc5b |
A |
T |
7: 141,421,115 (GRCm39) |
I4236F |
|
Het |
| Myh9 |
T |
C |
15: 77,655,432 (GRCm39) |
T1175A |
probably benign |
Het |
| Myt1l |
T |
A |
12: 29,861,564 (GRCm39) |
D115E |
unknown |
Het |
| Naa25 |
A |
G |
5: 121,552,573 (GRCm39) |
N167D |
probably benign |
Het |
| Ncam1 |
G |
A |
9: 49,431,493 (GRCm39) |
P648L |
probably damaging |
Het |
| Or2t26 |
T |
C |
11: 49,039,266 (GRCm39) |
Y61H |
probably damaging |
Het |
| Or2t44 |
A |
T |
11: 58,677,519 (GRCm39) |
D153V |
probably damaging |
Het |
| P3h3 |
G |
T |
6: 124,832,196 (GRCm39) |
A230E |
possibly damaging |
Het |
| Pacs2 |
A |
G |
12: 113,020,476 (GRCm39) |
E253G |
probably damaging |
Het |
| Pbld1 |
A |
T |
10: 62,901,648 (GRCm39) |
D57V |
probably benign |
Het |
| Pcsk5 |
T |
C |
19: 17,452,275 (GRCm39) |
T1077A |
probably damaging |
Het |
| Pou4f2 |
T |
A |
8: 79,161,932 (GRCm39) |
M224L |
|
Het |
| Ppcdc |
C |
T |
9: 57,342,265 (GRCm39) |
R19H |
probably benign |
Het |
| Ppp1r10 |
T |
A |
17: 36,241,018 (GRCm39) |
M640K |
probably benign |
Het |
| Prdx6 |
A |
T |
1: 161,069,432 (GRCm39) |
|
probably benign |
Het |
| Rab40b |
A |
G |
11: 121,250,384 (GRCm39) |
|
probably null |
Het |
| Rassf9 |
T |
A |
10: 102,381,329 (GRCm39) |
M237K |
probably benign |
Het |
| Rbbp8nl |
G |
T |
2: 179,919,769 (GRCm39) |
Y604* |
probably null |
Het |
| Reep2 |
G |
T |
18: 34,975,929 (GRCm39) |
W42L |
possibly damaging |
Het |
| Serpinb6e |
A |
T |
13: 34,017,261 (GRCm39) |
M253K |
probably damaging |
Het |
| Shank2 |
A |
G |
7: 143,623,927 (GRCm39) |
Q304R |
probably damaging |
Het |
| Slk |
T |
C |
19: 47,600,057 (GRCm39) |
M120T |
probably damaging |
Het |
| Spata31e5 |
T |
C |
1: 28,816,155 (GRCm39) |
I626V |
probably benign |
Het |
| Stc1 |
T |
G |
14: 69,269,884 (GRCm39) |
F155V |
possibly damaging |
Het |
| Tbc1d12 |
A |
G |
19: 38,899,510 (GRCm39) |
T477A |
probably damaging |
Het |
| Tmem19 |
T |
A |
10: 115,183,671 (GRCm39) |
I54F |
possibly damaging |
Het |
| Tmem62 |
G |
A |
2: 120,817,316 (GRCm39) |
|
probably null |
Het |
| Ttc6 |
A |
T |
12: 57,689,826 (GRCm39) |
R505S |
|
Het |
| Ttn |
G |
T |
2: 76,623,184 (GRCm39) |
R15418S |
probably damaging |
Het |
| Ugt2a3 |
C |
A |
5: 87,473,417 (GRCm39) |
C500F |
possibly damaging |
Het |
| Ugt2b35 |
T |
C |
5: 87,149,310 (GRCm39) |
F187S |
probably benign |
Het |
| Ung |
T |
A |
5: 114,269,456 (GRCm39) |
I56N |
probably damaging |
Het |
| Vmn1r17 |
G |
T |
6: 57,338,142 (GRCm39) |
F25L |
probably benign |
Het |
| Vmn1r29 |
C |
A |
6: 58,284,274 (GRCm39) |
|
probably benign |
Het |
| Vps26c |
T |
A |
16: 94,302,481 (GRCm39) |
I242F |
probably benign |
Het |
| Wdhd1 |
T |
C |
14: 47,504,470 (GRCm39) |
D368G |
probably benign |
Het |
| Wdr3 |
A |
T |
3: 100,057,259 (GRCm39) |
I448N |
probably damaging |
Het |
| Wdr47 |
T |
A |
3: 108,550,480 (GRCm39) |
M835K |
possibly damaging |
Het |
| Wt1 |
G |
A |
2: 104,957,584 (GRCm39) |
G10D |
possibly damaging |
Het |
| Zdhhc19 |
G |
A |
16: 32,316,500 (GRCm39) |
G85D |
probably damaging |
Het |
|
| Other mutations in Sphkap |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00332:Sphkap
|
APN |
1 |
83,258,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00337:Sphkap
|
APN |
1 |
83,317,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00470:Sphkap
|
APN |
1 |
83,255,631 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL00577:Sphkap
|
APN |
1 |
83,256,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00657:Sphkap
|
APN |
1 |
83,254,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01868:Sphkap
|
APN |
1 |
83,258,120 (GRCm39) |
splice site |
probably null |
|
|
IGL02101:Sphkap
|
APN |
1 |
83,268,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02471:Sphkap
|
APN |
1 |
83,253,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02945:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03008:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03031:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03059:Sphkap
|
APN |
1 |
83,234,963 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03085:Sphkap
|
APN |
1 |
83,258,075 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03355:Sphkap
|
APN |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03356:Sphkap
|
APN |
1 |
83,254,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03368:Sphkap
|
APN |
1 |
83,253,397 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0294:Sphkap
|
UTSW |
1 |
83,255,966 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0308:Sphkap
|
UTSW |
1 |
83,254,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0478:Sphkap
|
UTSW |
1 |
83,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Sphkap
|
UTSW |
1 |
83,258,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0678:Sphkap
|
UTSW |
1 |
83,256,349 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1216:Sphkap
|
UTSW |
1 |
83,268,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1253:Sphkap
|
UTSW |
1 |
83,256,619 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1532:Sphkap
|
UTSW |
1 |
83,234,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Sphkap
|
UTSW |
1 |
83,256,121 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1655:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1657:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1701:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1734:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1736:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1743:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1744:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1760:Sphkap
|
UTSW |
1 |
83,255,265 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1893:Sphkap
|
UTSW |
1 |
83,256,687 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1937:Sphkap
|
UTSW |
1 |
83,245,162 (GRCm39) |
nonsense |
probably null |
|
|
R1986:Sphkap
|
UTSW |
1 |
83,255,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1993:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R1995:Sphkap
|
UTSW |
1 |
83,255,236 (GRCm39) |
nonsense |
probably null |
|
|
R2001:Sphkap
|
UTSW |
1 |
83,254,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Sphkap
|
UTSW |
1 |
83,255,632 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2111:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2112:Sphkap
|
UTSW |
1 |
83,253,602 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2156:Sphkap
|
UTSW |
1 |
83,255,710 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2182:Sphkap
|
UTSW |
1 |
83,254,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Sphkap
|
UTSW |
1 |
83,234,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Sphkap
|
UTSW |
1 |
83,254,833 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3919:Sphkap
|
UTSW |
1 |
83,254,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3980:Sphkap
|
UTSW |
1 |
83,245,215 (GRCm39) |
splice site |
probably null |
|
|
R4130:Sphkap
|
UTSW |
1 |
83,255,619 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4539:Sphkap
|
UTSW |
1 |
83,255,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4602:Sphkap
|
UTSW |
1 |
83,256,782 (GRCm39) |
nonsense |
probably null |
|
|
R4735:Sphkap
|
UTSW |
1 |
83,256,838 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4793:Sphkap
|
UTSW |
1 |
83,255,805 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4849:Sphkap
|
UTSW |
1 |
83,255,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4880:Sphkap
|
UTSW |
1 |
83,266,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Sphkap
|
UTSW |
1 |
83,258,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5277:Sphkap
|
UTSW |
1 |
83,253,885 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5331:Sphkap
|
UTSW |
1 |
83,254,503 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5632:Sphkap
|
UTSW |
1 |
83,256,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5647:Sphkap
|
UTSW |
1 |
83,385,720 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5751:Sphkap
|
UTSW |
1 |
83,253,618 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5935:Sphkap
|
UTSW |
1 |
83,317,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5999:Sphkap
|
UTSW |
1 |
83,245,126 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6232:Sphkap
|
UTSW |
1 |
83,258,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6318:Sphkap
|
UTSW |
1 |
83,256,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Sphkap
|
UTSW |
1 |
83,256,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6602:Sphkap
|
UTSW |
1 |
83,253,479 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6674:Sphkap
|
UTSW |
1 |
83,255,555 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6716:Sphkap
|
UTSW |
1 |
83,339,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6803:Sphkap
|
UTSW |
1 |
83,258,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6880:Sphkap
|
UTSW |
1 |
83,234,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6941:Sphkap
|
UTSW |
1 |
83,385,811 (GRCm39) |
start gained |
probably benign |
|
|
R7170:Sphkap
|
UTSW |
1 |
83,243,706 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7263:Sphkap
|
UTSW |
1 |
83,254,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7422:Sphkap
|
UTSW |
1 |
83,241,547 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7640:Sphkap
|
UTSW |
1 |
83,256,649 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7722:Sphkap
|
UTSW |
1 |
83,256,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7810:Sphkap
|
UTSW |
1 |
83,254,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Sphkap
|
UTSW |
1 |
83,255,133 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7974:Sphkap
|
UTSW |
1 |
83,256,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7990:Sphkap
|
UTSW |
1 |
83,245,066 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8096:Sphkap
|
UTSW |
1 |
83,255,279 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8110:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8125:Sphkap
|
UTSW |
1 |
83,241,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8153:Sphkap
|
UTSW |
1 |
83,255,730 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8245:Sphkap
|
UTSW |
1 |
83,256,492 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8394:Sphkap
|
UTSW |
1 |
83,253,797 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8443:Sphkap
|
UTSW |
1 |
83,255,953 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8508:Sphkap
|
UTSW |
1 |
83,254,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8531:Sphkap
|
UTSW |
1 |
83,254,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Sphkap
|
UTSW |
1 |
83,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8674:Sphkap
|
UTSW |
1 |
83,255,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8682:Sphkap
|
UTSW |
1 |
83,256,997 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8837:Sphkap
|
UTSW |
1 |
83,253,384 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8857:Sphkap
|
UTSW |
1 |
83,258,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8902:Sphkap
|
UTSW |
1 |
83,256,685 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8916:Sphkap
|
UTSW |
1 |
83,255,108 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9154:Sphkap
|
UTSW |
1 |
83,234,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9579:Sphkap
|
UTSW |
1 |
83,255,295 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9616:Sphkap
|
UTSW |
1 |
83,254,989 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9781:Sphkap
|
UTSW |
1 |
83,255,772 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,256,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Sphkap
|
UTSW |
1 |
83,254,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,258,163 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
Z1176:Sphkap
|
UTSW |
1 |
83,253,754 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Sphkap
|
UTSW |
1 |
83,254,152 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCTTAACCATGGAGAGATAGGCATC -3'
(R):5'- TTGCTCCCTGGGAAGTAACAG -3'
Sequencing Primer
(F):5'- GCATCTCTAGGGATGAACAGCATTTG -3'
(R):5'- CTCCCTGGGAAGTAACAGTGTTTC -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation