Incidental Mutation 'R9378:Yeats2'
| ID |
709817 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Yeats2
|
| Ensembl Gene |
ENSMUSG00000041215 |
| Gene Name |
YEATS domain containing 2 |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.964)
|
| Stock # |
R9378 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
19959813-20051323 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 20033228 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1036
(V1036A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000087506
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000090052]
[ENSMUST00000115560]
[ENSMUST00000232019]
[ENSMUST00000232338]
|
| AlphaFold |
Q3TUF7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000090052
AA Change: V1036A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000087506
Gene: ENSMUSG00000041215
AA Change: V1036A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:YEATS
|
179 |
262 |
2.6e-27 |
PFAM |
|
low complexity region
|
299 |
309 |
N/A |
INTRINSIC |
|
low complexity region
|
312 |
333 |
N/A |
INTRINSIC |
|
low complexity region
|
409 |
429 |
N/A |
INTRINSIC |
|
low complexity region
|
458 |
467 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
471 |
675 |
3.72e-6 |
PROSPERO |
|
low complexity region
|
683 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
738 |
775 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
785 |
978 |
3.72e-6 |
PROSPERO |
|
low complexity region
|
1240 |
1249 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115560
AA Change: V1089A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000111222
Gene: ENSMUSG00000041215
AA Change: V1089A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:YEATS
|
232 |
314 |
2.1e-28 |
PFAM |
|
low complexity region
|
352 |
362 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
386 |
N/A |
INTRINSIC |
|
low complexity region
|
462 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
511 |
520 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
524 |
728 |
4.68e-6 |
PROSPERO |
|
low complexity region
|
736 |
755 |
N/A |
INTRINSIC |
|
low complexity region
|
791 |
828 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
838 |
1031 |
4.68e-6 |
PROSPERO |
|
low complexity region
|
1293 |
1302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232019
AA Change: V1051A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232338
|
| Predicted Effect |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] YEATS2 is a scaffolding subunit of the ADA2A (TADA2A; MIM 602276)-containing (ATAC) histone acetyltransferase complex (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010]
|
| Allele List at MGI |
All alleles(34) : Targeted(1) Gene trapped(33)
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
A |
G |
13: 77,471,735 (GRCm39) |
K1047E |
possibly damaging |
Het |
| Aadacl2fm1 |
A |
G |
3: 59,839,110 (GRCm39) |
T11A |
possibly damaging |
Het |
| Abca14 |
A |
T |
7: 119,807,191 (GRCm39) |
Y79F |
possibly damaging |
Het |
| Abca2 |
T |
A |
2: 25,329,094 (GRCm39) |
M978K |
probably benign |
Het |
| Adamts3 |
A |
T |
5: 89,848,269 (GRCm39) |
C684* |
probably null |
Het |
| Adnp2 |
T |
C |
18: 80,172,637 (GRCm39) |
T591A |
probably benign |
Het |
| Aff4 |
A |
T |
11: 53,263,306 (GRCm39) |
T109S |
probably damaging |
Het |
| Agmo |
A |
G |
12: 37,293,720 (GRCm39) |
I48V |
probably benign |
Het |
| Appl1 |
G |
A |
14: 26,649,784 (GRCm39) |
R581* |
probably null |
Het |
| Armc9 |
A |
T |
1: 86,189,766 (GRCm39) |
M714L |
probably benign |
Het |
| Atp6v0d2 |
T |
A |
4: 19,922,377 (GRCm39) |
T41S |
probably benign |
Het |
| Bin1 |
A |
T |
18: 32,552,921 (GRCm39) |
Q182L |
probably damaging |
Het |
| Bmp10 |
A |
G |
6: 87,410,684 (GRCm39) |
D159G |
probably benign |
Het |
| Bsn |
G |
A |
9: 107,984,854 (GRCm39) |
P295S |
possibly damaging |
Het |
| Cbx6 |
A |
G |
15: 79,712,606 (GRCm39) |
S274P |
probably damaging |
Het |
| Cdc20b |
A |
G |
13: 113,192,631 (GRCm39) |
K108R |
probably benign |
Het |
| Ces1d |
T |
A |
8: 93,912,724 (GRCm39) |
N238I |
probably damaging |
Het |
| Col7a1 |
C |
T |
9: 108,787,708 (GRCm39) |
Q663* |
probably null |
Het |
| Cpsf3 |
T |
C |
12: 21,358,039 (GRCm39) |
I517T |
possibly damaging |
Het |
| Cyp2a5 |
C |
A |
7: 26,539,879 (GRCm39) |
T309N |
probably damaging |
Het |
| Cyp2d40 |
A |
G |
15: 82,645,802 (GRCm39) |
F68L |
possibly damaging |
Het |
| Cyp7b1 |
A |
T |
3: 18,150,837 (GRCm39) |
W301R |
probably damaging |
Het |
| Dnah6 |
T |
A |
6: 73,189,513 (GRCm39) |
N45I |
probably benign |
Het |
| Dnah7a |
A |
T |
1: 53,621,776 (GRCm39) |
H1116Q |
probably benign |
Het |
| Dntt |
A |
G |
19: 41,027,356 (GRCm39) |
N141S |
probably benign |
Het |
| Fbxl13 |
T |
C |
5: 21,790,201 (GRCm39) |
N281D |
probably damaging |
Het |
| Frem2 |
A |
T |
3: 53,559,410 (GRCm39) |
L1699H |
probably damaging |
Het |
| Gabrr3 |
T |
C |
16: 59,282,037 (GRCm39) |
V464A |
possibly damaging |
Het |
| Gdap1 |
T |
A |
1: 17,227,353 (GRCm39) |
I160N |
probably damaging |
Het |
| Hnrnpll |
C |
A |
17: 80,369,291 (GRCm39) |
R44L |
unknown |
Het |
| Hsp90ab1 |
T |
C |
17: 45,881,680 (GRCm39) |
E187G |
probably damaging |
Het |
| Ighm |
T |
A |
12: 113,386,210 (GRCm39) |
T47S |
|
Het |
| Itgb7 |
A |
C |
15: 102,135,831 (GRCm39) |
|
probably null |
Het |
| Kif16b |
A |
T |
2: 142,461,738 (GRCm39) |
C1293* |
probably null |
Het |
| Klf11 |
C |
T |
12: 24,705,043 (GRCm39) |
R166C |
probably benign |
Het |
| Lca5l |
T |
A |
16: 95,977,212 (GRCm39) |
Q198L |
probably damaging |
Het |
| Lnx2 |
A |
T |
5: 146,961,180 (GRCm39) |
M584K |
probably benign |
Het |
| Lpp |
A |
T |
16: 24,540,737 (GRCm39) |
M1L |
probably benign |
Het |
| Lrig3 |
A |
G |
10: 125,832,953 (GRCm39) |
T276A |
probably damaging |
Het |
| Ltbp2 |
G |
A |
12: 84,837,864 (GRCm39) |
P1192L |
probably benign |
Het |
| Megf8 |
A |
T |
7: 25,039,840 (GRCm39) |
|
probably null |
Het |
| Myh1 |
A |
C |
11: 67,093,259 (GRCm39) |
T117P |
probably damaging |
Het |
| Neb |
C |
A |
2: 52,134,113 (GRCm39) |
R3290L |
possibly damaging |
Het |
| Neb |
A |
C |
2: 52,137,304 (GRCm39) |
V220G |
|
Het |
| Nktr |
A |
T |
9: 121,577,264 (GRCm39) |
K444I |
probably damaging |
Het |
| Nol11 |
A |
T |
11: 107,064,505 (GRCm39) |
M483K |
probably benign |
Het |
| Npy1r |
C |
A |
8: 67,156,861 (GRCm39) |
P94T |
probably damaging |
Het |
| Nsmaf |
T |
C |
4: 6,440,940 (GRCm39) |
T37A |
probably benign |
Het |
| Or10ad1b |
A |
G |
15: 98,124,920 (GRCm39) |
L204P |
possibly damaging |
Het |
| Or2y3 |
G |
A |
17: 38,393,056 (GRCm39) |
A271V |
possibly damaging |
Het |
| Or4c119 |
T |
C |
2: 88,987,399 (GRCm39) |
N40S |
probably damaging |
Het |
| Or51v8 |
A |
T |
7: 103,319,389 (GRCm39) |
M283K |
probably damaging |
Het |
| Or5w14 |
C |
A |
2: 87,541,423 (GRCm39) |
V276F |
possibly damaging |
Het |
| Or8a1b |
A |
G |
9: 37,623,473 (GRCm39) |
I34T |
probably damaging |
Het |
| Or8b37 |
G |
A |
9: 37,958,775 (GRCm39) |
V86M |
possibly damaging |
Het |
| Palld |
C |
T |
8: 61,969,691 (GRCm39) |
R1211H |
unknown |
Het |
| Pcdha3 |
A |
G |
18: 37,080,284 (GRCm39) |
D342G |
probably damaging |
Het |
| Pclo |
G |
A |
5: 14,815,877 (GRCm39) |
V1266I |
|
Het |
| Pcnx4 |
T |
C |
12: 72,602,664 (GRCm39) |
Y309H |
probably damaging |
Het |
| Pde8a |
C |
T |
7: 80,982,619 (GRCm39) |
T746I |
probably damaging |
Het |
| Pdzrn3 |
T |
G |
6: 101,127,772 (GRCm39) |
K965Q |
probably damaging |
Het |
| Phldb1 |
G |
A |
9: 44,615,425 (GRCm39) |
A225V |
probably benign |
Het |
| Pierce1 |
TCTCTGGGGCAGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTCTGGGGCAGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTCTGGGGCGGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTC |
TCTCTGGGGCAGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTCTGGGGCGGGCTTAGCCTTGGGCTCCCCCGGCTCCGGCTCCTC |
2: 28,356,122 (GRCm39) |
|
probably benign |
Het |
| Plat |
A |
G |
8: 23,265,599 (GRCm39) |
Y214C |
probably damaging |
Het |
| Plppr1 |
T |
A |
4: 49,325,627 (GRCm39) |
C274* |
probably null |
Het |
| Poglut1 |
A |
G |
16: 38,347,133 (GRCm39) |
F345L |
possibly damaging |
Het |
| Ppara |
A |
T |
15: 85,661,837 (GRCm39) |
E26V |
possibly damaging |
Het |
| Ppcdc |
A |
T |
9: 57,327,571 (GRCm39) |
W79R |
probably damaging |
Het |
| Prdm1 |
C |
T |
10: 44,316,150 (GRCm39) |
C662Y |
probably damaging |
Het |
| Sgms2 |
G |
A |
3: 131,136,011 (GRCm39) |
|
probably benign |
Het |
| Slc31a1 |
T |
A |
4: 62,306,843 (GRCm39) |
M133K |
probably damaging |
Het |
| Smg1 |
G |
A |
7: 117,777,998 (GRCm39) |
Q1309* |
probably null |
Het |
| Sos1 |
T |
C |
17: 80,761,239 (GRCm39) |
I152M |
probably damaging |
Het |
| Stk4 |
A |
T |
2: 163,952,136 (GRCm39) |
|
probably benign |
Het |
| Syne1 |
T |
G |
10: 5,200,954 (GRCm39) |
N3538T |
probably damaging |
Het |
| Tbc1d16 |
A |
G |
11: 119,099,666 (GRCm39) |
F236S |
probably damaging |
Het |
| Tgs1 |
T |
A |
4: 3,595,475 (GRCm39) |
M548K |
probably benign |
Het |
| Twf1 |
G |
A |
15: 94,483,336 (GRCm39) |
T124I |
probably damaging |
Het |
| Tyro3 |
G |
A |
2: 119,642,648 (GRCm39) |
G611R |
probably damaging |
Het |
| Unc13b |
T |
A |
4: 43,173,282 (GRCm39) |
I1370K |
unknown |
Het |
| Usp40 |
A |
G |
1: 87,885,032 (GRCm39) |
W939R |
probably damaging |
Het |
| Vamp8 |
A |
T |
6: 72,362,554 (GRCm39) |
V82E |
probably damaging |
Het |
| Vmn2r17 |
A |
G |
5: 109,575,732 (GRCm39) |
H201R |
possibly damaging |
Het |
| Whrn |
T |
C |
4: 63,350,079 (GRCm39) |
H546R |
probably benign |
Het |
| Zfp352 |
T |
G |
4: 90,112,575 (GRCm39) |
N238K |
probably benign |
Het |
| Zfp36l3 |
TCCAGGGGCGAGGGCAGCCCCAGGAGCAAGGGCCGCCCTAGGAATGAGGGCCGCCCCAGG |
TCCAGG |
X: 52,776,521 (GRCm39) |
|
probably benign |
Het |
| Zfp462 |
T |
A |
4: 55,011,510 (GRCm39) |
S1159T |
probably benign |
Het |
| Zscan4-ps1 |
A |
T |
7: 10,800,192 (GRCm39) |
H232Q |
probably benign |
Het |
|
| Other mutations in Yeats2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01118:Yeats2
|
APN |
16 |
20,005,054 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01128:Yeats2
|
APN |
16 |
19,980,718 (GRCm39) |
splice site |
probably benign |
|
|
IGL01139:Yeats2
|
APN |
16 |
20,033,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01394:Yeats2
|
APN |
16 |
19,980,782 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01482:Yeats2
|
APN |
16 |
20,041,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Yeats2
|
APN |
16 |
20,024,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01925:Yeats2
|
APN |
16 |
19,998,430 (GRCm39) |
splice site |
probably benign |
|
|
IGL02106:Yeats2
|
APN |
16 |
20,011,970 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL02370:Yeats2
|
APN |
16 |
19,969,221 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02447:Yeats2
|
APN |
16 |
20,012,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02669:Yeats2
|
APN |
16 |
20,005,033 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL03155:Yeats2
|
APN |
16 |
20,048,323 (GRCm39) |
critical splice donor site |
probably null |
|
|
tyrion
|
UTSW |
16 |
20,032,151 (GRCm39) |
splice site |
probably benign |
|
|
P0045:Yeats2
|
UTSW |
16 |
19,975,695 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0051:Yeats2
|
UTSW |
16 |
20,012,474 (GRCm39) |
nonsense |
probably null |
|
|
R0051:Yeats2
|
UTSW |
16 |
20,012,474 (GRCm39) |
nonsense |
probably null |
|
|
R0118:Yeats2
|
UTSW |
16 |
19,975,692 (GRCm39) |
nonsense |
probably null |
|
|
R0157:Yeats2
|
UTSW |
16 |
20,040,427 (GRCm39) |
makesense |
probably null |
|
|
R0184:Yeats2
|
UTSW |
16 |
20,022,435 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0194:Yeats2
|
UTSW |
16 |
19,971,719 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R0612:Yeats2
|
UTSW |
16 |
20,005,175 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0655:Yeats2
|
UTSW |
16 |
20,012,574 (GRCm39) |
nonsense |
probably null |
|
|
R0826:Yeats2
|
UTSW |
16 |
20,011,966 (GRCm39) |
nonsense |
probably null |
|
|
R1526:Yeats2
|
UTSW |
16 |
20,024,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Yeats2
|
UTSW |
16 |
20,008,115 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1749:Yeats2
|
UTSW |
16 |
20,005,018 (GRCm39) |
nonsense |
probably null |
|
|
R1842:Yeats2
|
UTSW |
16 |
19,989,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Yeats2
|
UTSW |
16 |
20,048,314 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1926:Yeats2
|
UTSW |
16 |
20,033,176 (GRCm39) |
missense |
probably benign |
|
|
R2000:Yeats2
|
UTSW |
16 |
20,005,141 (GRCm39) |
missense |
probably benign |
0.20 |
|
R2017:Yeats2
|
UTSW |
16 |
19,977,931 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2076:Yeats2
|
UTSW |
16 |
20,005,032 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2153:Yeats2
|
UTSW |
16 |
19,972,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2167:Yeats2
|
UTSW |
16 |
20,032,151 (GRCm39) |
splice site |
probably benign |
|
|
R2981:Yeats2
|
UTSW |
16 |
20,005,051 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3160:Yeats2
|
UTSW |
16 |
20,012,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3161:Yeats2
|
UTSW |
16 |
20,012,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Yeats2
|
UTSW |
16 |
20,012,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3774:Yeats2
|
UTSW |
16 |
19,969,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4250:Yeats2
|
UTSW |
16 |
19,975,685 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4305:Yeats2
|
UTSW |
16 |
20,027,172 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4455:Yeats2
|
UTSW |
16 |
19,980,743 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4458:Yeats2
|
UTSW |
16 |
20,032,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4811:Yeats2
|
UTSW |
16 |
19,971,645 (GRCm39) |
splice site |
probably null |
|
|
R4902:Yeats2
|
UTSW |
16 |
20,026,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5043:Yeats2
|
UTSW |
16 |
20,027,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5047:Yeats2
|
UTSW |
16 |
20,027,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5319:Yeats2
|
UTSW |
16 |
20,005,175 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5328:Yeats2
|
UTSW |
16 |
19,989,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5360:Yeats2
|
UTSW |
16 |
19,972,912 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5416:Yeats2
|
UTSW |
16 |
20,030,319 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5672:Yeats2
|
UTSW |
16 |
19,980,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5684:Yeats2
|
UTSW |
16 |
20,012,553 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5932:Yeats2
|
UTSW |
16 |
20,011,913 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5946:Yeats2
|
UTSW |
16 |
20,026,513 (GRCm39) |
nonsense |
probably null |
|
|
R6168:Yeats2
|
UTSW |
16 |
19,998,308 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6169:Yeats2
|
UTSW |
16 |
20,038,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6179:Yeats2
|
UTSW |
16 |
20,033,225 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6371:Yeats2
|
UTSW |
16 |
20,040,460 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R6877:Yeats2
|
UTSW |
16 |
19,998,344 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7149:Yeats2
|
UTSW |
16 |
19,972,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7405:Yeats2
|
UTSW |
16 |
20,041,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8353:Yeats2
|
UTSW |
16 |
20,041,637 (GRCm39) |
nonsense |
probably null |
|
|
R8367:Yeats2
|
UTSW |
16 |
20,041,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8453:Yeats2
|
UTSW |
16 |
20,041,637 (GRCm39) |
nonsense |
probably null |
|
|
R8506:Yeats2
|
UTSW |
16 |
19,971,684 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8535:Yeats2
|
UTSW |
16 |
19,977,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8828:Yeats2
|
UTSW |
16 |
19,969,260 (GRCm39) |
missense |
probably benign |
0.45 |
|
R8905:Yeats2
|
UTSW |
16 |
20,009,144 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8924:Yeats2
|
UTSW |
16 |
19,969,312 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9087:Yeats2
|
UTSW |
16 |
20,030,500 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9276:Yeats2
|
UTSW |
16 |
19,975,786 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9338:Yeats2
|
UTSW |
16 |
20,041,533 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9338:Yeats2
|
UTSW |
16 |
20,032,078 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9569:Yeats2
|
UTSW |
16 |
19,972,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9664:Yeats2
|
UTSW |
16 |
20,047,491 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGTGGCCAGGATATATTATATGC -3'
(R):5'- TGCAGCTTTCTTGAACCAGG -3'
Sequencing Primer
(F):5'- GTGGTTCAGTCGTTTTCTAC -3'
(R):5'- CAAACAGCTGACAGATGC -3'
|
| Posted On |
2022-04-18 |
Incidental Mutation