Incidental Mutation 'R1834:Thada'
| ID |
205117 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
039861-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1834 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 84533432 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1673
(V1673A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000047524
AA Change: V1673A
PolyPhen 2
Score 0.533 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: V1673A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.0606 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.0%
|
| Validation Efficiency |
97% (116/119) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 114 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310033P09Rik |
A |
G |
11: 59,099,313 (GRCm39) |
D20G |
probably damaging |
Het |
| 2310061N02Rik |
T |
A |
16: 88,504,786 (GRCm39) |
S4C |
unknown |
Het |
| Abca3 |
A |
T |
17: 24,595,666 (GRCm39) |
N340Y |
probably benign |
Het |
| Abcc1 |
A |
G |
16: 14,240,981 (GRCm39) |
I513V |
possibly damaging |
Het |
| Acacb |
C |
T |
5: 114,373,536 (GRCm39) |
T1855M |
probably damaging |
Het |
| Ace |
A |
G |
11: 105,876,920 (GRCm39) |
|
probably benign |
Het |
| Acss2 |
T |
A |
2: 155,400,550 (GRCm39) |
Y530N |
probably damaging |
Het |
| Adarb1 |
C |
A |
10: 77,153,065 (GRCm39) |
|
probably benign |
Het |
| Afm |
T |
A |
5: 90,674,283 (GRCm39) |
M265K |
probably benign |
Het |
| Agl |
A |
G |
3: 116,582,000 (GRCm39) |
F293S |
probably benign |
Het |
| Aox1 |
G |
A |
1: 58,348,150 (GRCm39) |
A623T |
probably benign |
Het |
| Arhgap31 |
C |
A |
16: 38,424,065 (GRCm39) |
S667I |
probably benign |
Het |
| Bco1 |
A |
G |
8: 117,844,176 (GRCm39) |
T297A |
probably benign |
Het |
| Bmp1 |
T |
C |
14: 70,746,271 (GRCm39) |
S123G |
possibly damaging |
Het |
| Caps2 |
G |
A |
10: 112,031,623 (GRCm39) |
D283N |
possibly damaging |
Het |
| Ccdc57 |
A |
C |
11: 120,752,045 (GRCm39) |
S845R |
probably benign |
Het |
| Cd209f |
A |
G |
8: 4,154,491 (GRCm39) |
S119P |
probably damaging |
Het |
| Chrna6 |
A |
G |
8: 27,897,242 (GRCm39) |
S212P |
probably benign |
Het |
| Col10a1 |
G |
C |
10: 34,271,011 (GRCm39) |
A328P |
probably damaging |
Het |
| Col4a2 |
A |
G |
8: 11,452,997 (GRCm39) |
E188G |
probably benign |
Het |
| Creb1 |
C |
T |
1: 64,590,109 (GRCm39) |
Q32* |
probably null |
Het |
| Cttnbp2 |
C |
T |
6: 18,501,965 (GRCm39) |
V16M |
probably damaging |
Het |
| D430041D05Rik |
A |
G |
2: 103,998,446 (GRCm39) |
S1102P |
probably damaging |
Het |
| Ddx31 |
C |
T |
2: 28,782,465 (GRCm39) |
H603Y |
probably damaging |
Het |
| Ddx52 |
G |
A |
11: 83,850,323 (GRCm39) |
C568Y |
probably benign |
Het |
| Dgki |
C |
A |
6: 37,011,636 (GRCm39) |
|
probably benign |
Het |
| Dmrt1 |
A |
T |
19: 25,487,063 (GRCm39) |
Q123L |
probably damaging |
Het |
| Dnah5 |
A |
T |
15: 28,409,270 (GRCm39) |
M3563L |
probably benign |
Het |
| Dnah7b |
A |
T |
1: 46,272,919 (GRCm39) |
N2349I |
possibly damaging |
Het |
| Dscaml1 |
T |
G |
9: 45,594,930 (GRCm39) |
S678A |
probably benign |
Het |
| Ece1 |
C |
T |
4: 137,685,312 (GRCm39) |
R601W |
probably damaging |
Het |
| Ece1 |
A |
G |
4: 137,685,439 (GRCm39) |
N643S |
probably damaging |
Het |
| Eno1b |
A |
G |
18: 48,180,530 (GRCm39) |
Y236C |
probably damaging |
Het |
| Esco1 |
T |
C |
18: 10,594,350 (GRCm39) |
E312G |
probably damaging |
Het |
| Eya3 |
T |
A |
4: 132,434,429 (GRCm39) |
V276E |
probably damaging |
Het |
| Fam161b |
A |
G |
12: 84,395,552 (GRCm39) |
|
probably benign |
Het |
| Fem1c |
C |
T |
18: 46,638,349 (GRCm39) |
G551D |
probably damaging |
Het |
| Fer1l6 |
T |
C |
15: 58,429,718 (GRCm39) |
I155T |
possibly damaging |
Het |
| Gbp7 |
A |
G |
3: 142,240,441 (GRCm39) |
Y53C |
probably damaging |
Het |
| Gjb3 |
G |
A |
4: 127,220,224 (GRCm39) |
R103W |
probably damaging |
Het |
| Gm10030 |
C |
T |
9: 110,833,947 (GRCm39) |
|
noncoding transcript |
Het |
| Gm3443 |
T |
A |
19: 21,533,043 (GRCm39) |
H2Q |
unknown |
Het |
| Gm5800 |
T |
C |
14: 51,953,549 (GRCm39) |
E22G |
possibly damaging |
Het |
| Gsdma2 |
G |
T |
11: 98,539,905 (GRCm39) |
R9L |
probably damaging |
Het |
| Gvin3 |
A |
T |
7: 106,202,983 (GRCm39) |
V87D |
possibly damaging |
Het |
| Ica1l |
A |
G |
1: 60,067,395 (GRCm39) |
|
probably benign |
Het |
| Ice1 |
G |
A |
13: 70,763,457 (GRCm39) |
T167I |
probably damaging |
Het |
| Ifi204 |
T |
A |
1: 173,575,172 (GRCm39) |
R618S |
unknown |
Het |
| Itga2 |
C |
A |
13: 114,993,262 (GRCm39) |
K784N |
probably damaging |
Het |
| Itga2 |
T |
A |
13: 114,993,263 (GRCm39) |
K784M |
probably damaging |
Het |
| Kif3b |
A |
G |
2: 153,159,405 (GRCm39) |
E402G |
probably benign |
Het |
| Lrp2 |
T |
C |
2: 69,297,224 (GRCm39) |
I3246V |
probably benign |
Het |
| Lrrn3 |
G |
T |
12: 41,503,517 (GRCm39) |
L267I |
probably damaging |
Het |
| Map1s |
A |
G |
8: 71,369,055 (GRCm39) |
Y868C |
probably damaging |
Het |
| Mcm5 |
A |
G |
8: 75,845,901 (GRCm39) |
T370A |
possibly damaging |
Het |
| Nat8f7 |
T |
C |
6: 85,684,793 (GRCm39) |
S16G |
probably benign |
Het |
| Nav3 |
T |
C |
10: 109,555,883 (GRCm39) |
T1683A |
probably damaging |
Het |
| Nbeal2 |
T |
C |
9: 110,456,197 (GRCm39) |
N2417S |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,126,907 (GRCm39) |
N3605S |
probably damaging |
Het |
| Net1 |
A |
T |
13: 3,962,941 (GRCm39) |
|
probably benign |
Het |
| Nsd1 |
A |
G |
13: 55,461,164 (GRCm39) |
T2464A |
possibly damaging |
Het |
| Nt5e |
T |
A |
9: 88,252,240 (GRCm39) |
I534N |
probably damaging |
Het |
| Nudt12 |
T |
A |
17: 59,318,071 (GRCm39) |
H58L |
probably damaging |
Het |
| Ocrl |
T |
A |
X: 47,050,993 (GRCm39) |
I74N |
probably damaging |
Het |
| Or1a1 |
A |
G |
11: 74,086,479 (GRCm39) |
H50R |
probably benign |
Het |
| Or2ag13 |
A |
G |
7: 106,473,348 (GRCm39) |
Y35H |
probably damaging |
Het |
| Or5ae2 |
A |
G |
7: 84,505,690 (GRCm39) |
T38A |
probably damaging |
Het |
| Or9k2b |
A |
G |
10: 130,016,701 (GRCm39) |
I16T |
probably benign |
Het |
| Pef1 |
C |
A |
4: 130,014,966 (GRCm39) |
C10* |
probably null |
Het |
| Phf21b |
A |
G |
15: 84,681,547 (GRCm39) |
Y256H |
probably damaging |
Het |
| Phox2a |
G |
T |
7: 101,470,152 (GRCm39) |
|
probably null |
Het |
| Pi16 |
A |
G |
17: 29,546,419 (GRCm39) |
E399G |
possibly damaging |
Het |
| Pipox |
A |
T |
11: 77,772,949 (GRCm39) |
Y321N |
probably damaging |
Het |
| Plin4 |
A |
G |
17: 56,410,522 (GRCm39) |
S1170P |
probably damaging |
Het |
| Pnma2 |
C |
T |
14: 67,154,662 (GRCm39) |
S362L |
possibly damaging |
Het |
| Ppp1r9a |
T |
C |
6: 5,113,710 (GRCm39) |
I738T |
probably damaging |
Het |
| Prkcsh |
A |
T |
9: 21,919,634 (GRCm39) |
K188M |
probably damaging |
Het |
| Rcc1l |
A |
T |
5: 134,192,498 (GRCm39) |
Y309N |
probably damaging |
Het |
| Ripk1 |
A |
G |
13: 34,199,196 (GRCm39) |
T123A |
probably benign |
Het |
| Robo4 |
A |
G |
9: 37,324,355 (GRCm39) |
D961G |
probably benign |
Het |
| Rps27a |
A |
G |
11: 29,496,299 (GRCm39) |
Y105H |
probably benign |
Het |
| Scaper |
A |
G |
9: 55,724,018 (GRCm39) |
Y641H |
possibly damaging |
Het |
| Scn1a |
C |
A |
2: 66,154,960 (GRCm39) |
Q666H |
probably benign |
Het |
| Scn1a |
T |
A |
2: 66,154,961 (GRCm39) |
Q666L |
probably benign |
Het |
| Sdhaf4 |
T |
C |
1: 24,042,234 (GRCm39) |
|
probably null |
Het |
| Sec14l3 |
A |
G |
11: 4,016,510 (GRCm39) |
|
probably benign |
Het |
| Selp |
C |
A |
1: 163,955,729 (GRCm39) |
|
probably null |
Het |
| Sim1 |
A |
G |
10: 50,785,924 (GRCm39) |
D259G |
probably damaging |
Het |
| Sptan1 |
T |
A |
2: 29,882,013 (GRCm39) |
|
probably benign |
Het |
| Sptbn4 |
T |
A |
7: 27,066,071 (GRCm39) |
E679V |
probably null |
Het |
| Sytl3 |
G |
A |
17: 6,995,726 (GRCm39) |
E169K |
probably benign |
Het |
| Taar1 |
T |
C |
10: 23,797,087 (GRCm39) |
C262R |
probably benign |
Het |
| Taf7l2 |
T |
C |
10: 115,948,570 (GRCm39) |
R319G |
probably benign |
Het |
| Tbc1d32 |
A |
G |
10: 55,893,700 (GRCm39) |
I1291T |
probably benign |
Het |
| Tet1 |
G |
A |
10: 62,649,444 (GRCm39) |
P89S |
probably damaging |
Het |
| Tgfbrap1 |
C |
A |
1: 43,110,795 (GRCm39) |
G7W |
probably damaging |
Het |
| Thbs4 |
A |
G |
13: 92,897,989 (GRCm39) |
V610A |
probably benign |
Het |
| Tmem163 |
A |
G |
1: 127,605,246 (GRCm39) |
S41P |
probably benign |
Het |
| Tmem65 |
A |
T |
15: 58,658,962 (GRCm39) |
H200Q |
probably damaging |
Het |
| Trgc3 |
A |
G |
13: 19,447,535 (GRCm39) |
T163A |
possibly damaging |
Het |
| Trim62 |
T |
C |
4: 128,803,018 (GRCm39) |
V356A |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,562,502 (GRCm39) |
D28781G |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,593,604 (GRCm39) |
V20679I |
probably benign |
Het |
| Tut7 |
A |
T |
13: 59,962,749 (GRCm39) |
Y339* |
probably null |
Het |
| Unc80 |
A |
T |
1: 66,678,407 (GRCm39) |
T2063S |
possibly damaging |
Het |
| Vav3 |
A |
G |
3: 109,413,742 (GRCm39) |
T227A |
probably benign |
Het |
| Vmn2r118 |
A |
T |
17: 55,899,456 (GRCm39) |
I816N |
probably damaging |
Het |
| Vmn2r26 |
T |
A |
6: 124,038,369 (GRCm39) |
M648K |
possibly damaging |
Het |
| Vmn2r88 |
T |
G |
14: 51,650,487 (GRCm39) |
|
probably benign |
Het |
| Vwa3a |
A |
G |
7: 120,389,359 (GRCm39) |
T66A |
probably benign |
Het |
| Xirp2 |
T |
A |
2: 67,341,484 (GRCm39) |
Y1242N |
probably damaging |
Het |
| Ywhag |
G |
A |
5: 135,940,384 (GRCm39) |
T70M |
probably damaging |
Het |
| Zfp248 |
T |
C |
6: 118,405,931 (GRCm39) |
T452A |
probably damaging |
Het |
| Zfp988 |
A |
T |
4: 147,417,344 (GRCm39) |
I593F |
probably damaging |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCCTGGAATGTGTGTCTC -3'
(R):5'- AGCTCTTGTTACTGGCTGC -3'
Sequencing Primer
(F):5'- TGGAATGTGTGTCTCTTCCTC -3'
(R):5'- GTGGCTTCCCAATAAACCTGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation