Incidental Mutation 'R1911:Arid1b'
| ID |
210314 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arid1b
|
| Ensembl Gene |
ENSMUSG00000069729 |
| Gene Name |
AT-rich interaction domain 1B |
| Synonyms |
9330189K18Rik, B230217J03Rik |
| MMRRC Submission |
039929-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.783)
|
| Stock # |
R1911 (G1)
|
| Quality Score |
224 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
5044607-5397931 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 5393241 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 2257
(E2257G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156119
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092723]
[ENSMUST00000115797]
[ENSMUST00000115799]
[ENSMUST00000232180]
|
| AlphaFold |
E9Q4N7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000092723
AA Change: E2204G
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000090398
Gene: ENSMUSG00000069729
AA Change: E2204G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
150 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
257 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
371 |
N/A |
INTRINSIC |
|
low complexity region
|
379 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
485 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
574 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
640 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
707 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
740 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
773 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
816 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
974 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1045 |
N/A |
INTRINSIC |
|
ARID
|
1057 |
1147 |
9.9e-33 |
SMART |
|
BRIGHT
|
1061 |
1152 |
7.62e-41 |
SMART |
|
low complexity region
|
1166 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1336 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1456 |
N/A |
INTRINSIC |
|
low complexity region
|
1473 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1579 |
1595 |
N/A |
INTRINSIC |
|
coiled coil region
|
1724 |
1745 |
N/A |
INTRINSIC |
|
low complexity region
|
1835 |
1843 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1933 |
2189 |
1.5e-152 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000115797
AA Change: E2205G
PolyPhen 2
Score 0.968 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000111463
Gene: ENSMUSG00000069729
AA Change: E2205G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
149 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
180 |
195 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
386 |
424 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
506 |
N/A |
INTRINSIC |
|
low complexity region
|
522 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
563 |
588 |
N/A |
INTRINSIC |
|
low complexity region
|
639 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
688 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
860 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
922 |
933 |
N/A |
INTRINSIC |
|
Blast:ARID
|
981 |
1028 |
1e-8 |
BLAST |
|
low complexity region
|
1029 |
1054 |
N/A |
INTRINSIC |
|
ARID
|
1058 |
1148 |
9.9e-33 |
SMART |
|
BRIGHT
|
1062 |
1153 |
7.62e-41 |
SMART |
|
low complexity region
|
1167 |
1178 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1457 |
N/A |
INTRINSIC |
|
low complexity region
|
1474 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1580 |
1596 |
N/A |
INTRINSIC |
|
coiled coil region
|
1725 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1836 |
1844 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1935 |
2190 |
6.3e-121 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000115799
AA Change: E1723G
PolyPhen 2
Score 0.968 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000111465
Gene: ENSMUSG00000069729
AA Change: E1723G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
70 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
92 |
107 |
N/A |
INTRINSIC |
|
low complexity region
|
111 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
187 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
282 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
451 |
N/A |
INTRINSIC |
|
Blast:ARID
|
499 |
546 |
1e-8 |
BLAST |
|
low complexity region
|
547 |
572 |
N/A |
INTRINSIC |
|
ARID
|
576 |
666 |
9.9e-33 |
SMART |
|
BRIGHT
|
580 |
671 |
7.62e-41 |
SMART |
|
low complexity region
|
685 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
776 |
787 |
N/A |
INTRINSIC |
|
low complexity region
|
855 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
945 |
975 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1005 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1114 |
N/A |
INTRINSIC |
|
coiled coil region
|
1243 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1362 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1452 |
1708 |
1.1e-152 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000232180
AA Change: E2257G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Meta Mutation Damage Score |
0.1482 |
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.2%
|
| Validation Efficiency |
99% (99/100) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
All alleles(61) : Targeted(2) Gene trapped(59)
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930590J08Rik |
T |
A |
6: 91,927,050 (GRCm39) |
|
probably benign |
Het |
| Abca7 |
T |
C |
10: 79,842,468 (GRCm39) |
V1134A |
probably benign |
Het |
| Acaa2 |
A |
G |
18: 74,925,483 (GRCm39) |
E82G |
probably benign |
Het |
| Acap1 |
T |
C |
11: 69,772,548 (GRCm39) |
D521G |
probably damaging |
Het |
| Adam19 |
T |
C |
11: 46,012,281 (GRCm39) |
V259A |
probably damaging |
Het |
| Adss1 |
T |
C |
12: 112,599,443 (GRCm39) |
V140A |
probably benign |
Het |
| Aif1 |
G |
A |
17: 35,391,127 (GRCm39) |
P44L |
probably benign |
Het |
| Aldh3b1 |
T |
G |
19: 3,971,187 (GRCm39) |
D159A |
probably damaging |
Het |
| Ank1 |
T |
C |
8: 23,589,666 (GRCm39) |
V589A |
probably damaging |
Het |
| Ano2 |
G |
A |
6: 125,990,654 (GRCm39) |
D803N |
probably benign |
Het |
| Asb17 |
T |
C |
3: 153,550,138 (GRCm39) |
Y57H |
probably benign |
Het |
| Asph |
T |
C |
4: 9,453,335 (GRCm39) |
E646G |
probably damaging |
Het |
| Aspm |
T |
A |
1: 139,405,832 (GRCm39) |
I1573K |
probably benign |
Het |
| Bcas1 |
C |
A |
2: 170,229,863 (GRCm39) |
D236Y |
probably damaging |
Het |
| Bcas2 |
G |
T |
3: 103,079,113 (GRCm39) |
G9* |
probably null |
Het |
| Btaf1 |
A |
G |
19: 36,964,030 (GRCm39) |
Q867R |
probably benign |
Het |
| Calhm3 |
C |
T |
19: 47,143,908 (GRCm39) |
V132I |
possibly damaging |
Het |
| Ccer1 |
A |
T |
10: 97,530,539 (GRCm39) |
I401F |
possibly damaging |
Het |
| Cdcp3 |
T |
C |
7: 130,839,818 (GRCm39) |
V580A |
probably damaging |
Het |
| Cecr2 |
T |
A |
6: 120,739,526 (GRCm39) |
|
probably benign |
Het |
| Cep104 |
G |
A |
4: 154,091,255 (GRCm39) |
R925Q |
possibly damaging |
Het |
| Cep164 |
T |
A |
9: 45,682,104 (GRCm39) |
M1900L |
probably benign |
Het |
| Crybg1 |
A |
G |
10: 43,873,673 (GRCm39) |
V1145A |
possibly damaging |
Het |
| Cyp2a4 |
T |
A |
7: 26,008,399 (GRCm39) |
N180K |
possibly damaging |
Het |
| Dennd4a |
T |
C |
9: 64,796,368 (GRCm39) |
L798P |
probably damaging |
Het |
| Dmxl1 |
T |
C |
18: 50,011,230 (GRCm39) |
I1129T |
probably benign |
Het |
| Dnah2 |
T |
C |
11: 69,406,578 (GRCm39) |
N555D |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,601,029 (GRCm39) |
M988K |
probably damaging |
Het |
| Elp4 |
T |
A |
2: 105,533,088 (GRCm39) |
H419L |
probably damaging |
Het |
| Endov |
T |
C |
11: 119,393,177 (GRCm39) |
V109A |
possibly damaging |
Het |
| Epha8 |
T |
C |
4: 136,663,625 (GRCm39) |
Y477C |
probably damaging |
Het |
| Erlin1 |
A |
G |
19: 44,037,561 (GRCm39) |
M188T |
probably damaging |
Het |
| Fhip1a |
T |
A |
3: 85,568,525 (GRCm39) |
D998V |
probably benign |
Het |
| Fhod3 |
A |
T |
18: 25,245,643 (GRCm39) |
D1231V |
possibly damaging |
Het |
| Gimap3 |
T |
A |
6: 48,742,646 (GRCm39) |
I95F |
possibly damaging |
Het |
| Gm10717 |
T |
G |
9: 3,026,317 (GRCm39) |
F205C |
probably damaging |
Het |
| Grk1 |
C |
A |
8: 13,457,923 (GRCm39) |
D274E |
probably damaging |
Het |
| Gsdmc2 |
G |
A |
15: 63,699,621 (GRCm39) |
A269V |
probably benign |
Het |
| Krt33a |
T |
A |
11: 99,903,175 (GRCm39) |
Q289L |
probably benign |
Het |
| Krt76 |
T |
A |
15: 101,796,600 (GRCm39) |
K403* |
probably null |
Het |
| Lcn4 |
T |
C |
2: 26,560,607 (GRCm39) |
|
probably benign |
Het |
| Mab21l1 |
T |
C |
3: 55,691,048 (GRCm39) |
S212P |
possibly damaging |
Het |
| Mapk8ip3 |
A |
C |
17: 25,123,025 (GRCm39) |
D610E |
probably benign |
Het |
| Mastl |
G |
T |
2: 23,022,692 (GRCm39) |
S677* |
probably null |
Het |
| Mfap3 |
T |
C |
11: 57,420,562 (GRCm39) |
F181S |
probably damaging |
Het |
| Mlkl |
T |
C |
8: 112,038,732 (GRCm39) |
|
probably benign |
Het |
| Mov10 |
G |
A |
3: 104,708,876 (GRCm39) |
|
probably benign |
Het |
| Muc5ac |
T |
C |
7: 141,350,041 (GRCm39) |
F595L |
probably benign |
Het |
| Nbas |
T |
A |
12: 13,616,145 (GRCm39) |
C2228S |
probably benign |
Het |
| Nit2 |
G |
A |
16: 56,982,046 (GRCm39) |
|
probably benign |
Het |
| Nod1 |
C |
T |
6: 54,921,425 (GRCm39) |
V298M |
probably damaging |
Het |
| Or3a4 |
C |
A |
11: 73,945,210 (GRCm39) |
R125L |
probably damaging |
Het |
| Or4c111 |
A |
G |
2: 88,843,565 (GRCm39) |
L281P |
probably damaging |
Het |
| Or52b1 |
T |
A |
7: 104,978,590 (GRCm39) |
I270F |
probably benign |
Het |
| Or6c210 |
A |
T |
10: 129,495,981 (GRCm39) |
D102V |
probably benign |
Het |
| Or7g12 |
T |
C |
9: 18,900,196 (GRCm39) |
L304P |
probably damaging |
Het |
| Osbpl5 |
C |
A |
7: 143,243,662 (GRCm39) |
R864L |
probably benign |
Het |
| Pcnt |
G |
A |
10: 76,204,650 (GRCm39) |
T2585M |
possibly damaging |
Het |
| Pepd |
C |
T |
7: 34,634,174 (GRCm39) |
|
probably benign |
Het |
| Pou6f2 |
T |
C |
13: 18,326,548 (GRCm39) |
I341V |
probably damaging |
Het |
| Pramel32 |
T |
C |
4: 88,548,309 (GRCm39) |
Q32R |
possibly damaging |
Het |
| Prune2 |
T |
A |
19: 17,091,038 (GRCm39) |
F281I |
probably benign |
Het |
| Psg19 |
T |
G |
7: 18,528,193 (GRCm39) |
Q183H |
probably damaging |
Het |
| Psme4 |
T |
G |
11: 30,765,658 (GRCm39) |
S587A |
probably benign |
Het |
| Ptpro |
T |
C |
6: 137,377,617 (GRCm39) |
|
probably benign |
Het |
| Pttg1ip2 |
C |
A |
5: 5,502,019 (GRCm39) |
W144C |
probably benign |
Het |
| Rasgrp4 |
T |
C |
7: 28,838,302 (GRCm39) |
V92A |
probably damaging |
Het |
| Rem1 |
G |
A |
2: 152,476,455 (GRCm39) |
V238M |
probably damaging |
Het |
| Rexo5 |
C |
T |
7: 119,398,867 (GRCm39) |
A68V |
probably damaging |
Het |
| Robo2 |
A |
T |
16: 73,755,213 (GRCm39) |
N769K |
probably damaging |
Het |
| Sfrp5 |
C |
T |
19: 42,187,237 (GRCm39) |
V278I |
probably benign |
Het |
| Sidt1 |
A |
G |
16: 44,102,234 (GRCm39) |
S309P |
possibly damaging |
Het |
| Slc22a6 |
A |
C |
19: 8,599,246 (GRCm39) |
Q292H |
probably benign |
Het |
| Slc4a3 |
G |
A |
1: 75,530,367 (GRCm39) |
R690H |
probably damaging |
Het |
| Snx7 |
A |
T |
3: 117,623,317 (GRCm39) |
|
probably null |
Het |
| Spag6 |
T |
A |
2: 18,720,616 (GRCm39) |
Y129* |
probably null |
Het |
| Srcap |
T |
C |
7: 127,133,994 (GRCm39) |
I905T |
probably damaging |
Het |
| St6gal1 |
T |
G |
16: 23,140,383 (GRCm39) |
S185A |
probably damaging |
Het |
| Sult6b1 |
G |
A |
17: 79,196,393 (GRCm39) |
H250Y |
possibly damaging |
Het |
| Tdrd6 |
T |
G |
17: 43,937,979 (GRCm39) |
N1023T |
probably benign |
Het |
| Tecta |
C |
T |
9: 42,249,232 (GRCm39) |
E1877K |
probably damaging |
Het |
| Tex10 |
C |
T |
4: 48,456,800 (GRCm39) |
R637Q |
probably benign |
Het |
| Tex14 |
T |
A |
11: 87,385,861 (GRCm39) |
D240E |
probably damaging |
Het |
| Tex47 |
T |
C |
5: 7,355,022 (GRCm39) |
Y68H |
probably damaging |
Het |
| Thbs2 |
A |
G |
17: 14,910,104 (GRCm39) |
V165A |
probably benign |
Het |
| Tmem126b |
T |
A |
7: 90,118,367 (GRCm39) |
Y171F |
possibly damaging |
Het |
| Tpsg1 |
G |
T |
17: 25,592,374 (GRCm39) |
M46I |
probably benign |
Het |
| Trmt2a |
A |
G |
16: 18,069,070 (GRCm39) |
K304R |
probably benign |
Het |
| Ttc28 |
G |
T |
5: 111,428,616 (GRCm39) |
R1845L |
possibly damaging |
Het |
| Umodl1 |
A |
T |
17: 31,211,128 (GRCm39) |
T884S |
possibly damaging |
Het |
| Vmn2r77 |
A |
G |
7: 86,461,001 (GRCm39) |
K776E |
probably damaging |
Het |
| Vmn2r88 |
T |
C |
14: 51,655,671 (GRCm39) |
S627P |
probably damaging |
Het |
| Vrk1 |
T |
C |
12: 106,024,236 (GRCm39) |
|
probably null |
Het |
| Zfp644 |
A |
G |
5: 106,783,137 (GRCm39) |
M1079T |
possibly damaging |
Het |
| Znrf1 |
T |
C |
8: 112,348,233 (GRCm39) |
*41Q |
probably null |
Het |
| Znrf1 |
T |
C |
8: 112,348,244 (GRCm39) |
F183L |
possibly damaging |
Het |
|
| Other mutations in Arid1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Arid1b
|
APN |
17 |
5,387,385 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00340:Arid1b
|
APN |
17 |
5,371,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00886:Arid1b
|
APN |
17 |
5,177,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01161:Arid1b
|
APN |
17 |
5,392,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01391:Arid1b
|
APN |
17 |
5,369,133 (GRCm39) |
splice site |
probably benign |
|
|
IGL01456:Arid1b
|
APN |
17 |
5,341,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02152:Arid1b
|
APN |
17 |
5,364,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02288:Arid1b
|
APN |
17 |
5,314,315 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02713:Arid1b
|
APN |
17 |
5,393,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arid1b
|
APN |
17 |
5,392,166 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02885:Arid1b
|
APN |
17 |
5,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Arid1b
|
APN |
17 |
5,385,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4449:Arid1b
|
UTSW |
17 |
5,045,864 (GRCm39) |
small insertion |
probably benign |
|
|
PIT4142001:Arid1b
|
UTSW |
17 |
5,389,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Arid1b
|
UTSW |
17 |
5,364,309 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0124:Arid1b
|
UTSW |
17 |
5,389,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Arid1b
|
UTSW |
17 |
5,393,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Arid1b
|
UTSW |
17 |
5,046,535 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0825:Arid1b
|
UTSW |
17 |
5,392,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1172:Arid1b
|
UTSW |
17 |
5,389,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Arid1b
|
UTSW |
17 |
5,389,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Arid1b
|
UTSW |
17 |
5,329,476 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1760:Arid1b
|
UTSW |
17 |
5,392,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1812:Arid1b
|
UTSW |
17 |
5,387,304 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3874:Arid1b
|
UTSW |
17 |
5,386,790 (GRCm39) |
splice site |
probably null |
|
|
R3913:Arid1b
|
UTSW |
17 |
5,392,532 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3916:Arid1b
|
UTSW |
17 |
5,392,928 (GRCm39) |
missense |
probably benign |
0.25 |
|
R3922:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4119:Arid1b
|
UTSW |
17 |
5,046,069 (GRCm39) |
unclassified |
probably benign |
|
|
R4290:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4352:Arid1b
|
UTSW |
17 |
5,147,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4386:Arid1b
|
UTSW |
17 |
5,045,247 (GRCm39) |
unclassified |
probably benign |
|
|
R4458:Arid1b
|
UTSW |
17 |
5,293,191 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4524:Arid1b
|
UTSW |
17 |
5,147,895 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4622:Arid1b
|
UTSW |
17 |
5,045,325 (GRCm39) |
unclassified |
probably benign |
|
|
R4723:Arid1b
|
UTSW |
17 |
5,387,565 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4782:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4910:Arid1b
|
UTSW |
17 |
5,392,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Arid1b
|
UTSW |
17 |
5,393,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5083:Arid1b
|
UTSW |
17 |
5,364,293 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5204:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5347:Arid1b
|
UTSW |
17 |
5,341,332 (GRCm39) |
nonsense |
probably null |
|
|
R5553:Arid1b
|
UTSW |
17 |
5,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5713:Arid1b
|
UTSW |
17 |
5,387,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5820:Arid1b
|
UTSW |
17 |
5,046,529 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5992:Arid1b
|
UTSW |
17 |
5,045,231 (GRCm39) |
unclassified |
probably benign |
|
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6153:Arid1b
|
UTSW |
17 |
5,293,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6222:Arid1b
|
UTSW |
17 |
5,377,922 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6249:Arid1b
|
UTSW |
17 |
5,329,636 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R6279:Arid1b
|
UTSW |
17 |
5,392,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6329:Arid1b
|
UTSW |
17 |
5,387,538 (GRCm39) |
nonsense |
probably null |
|
|
R6368:Arid1b
|
UTSW |
17 |
5,382,808 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6466:Arid1b
|
UTSW |
17 |
5,377,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6861:Arid1b
|
UTSW |
17 |
5,377,961 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7008:Arid1b
|
UTSW |
17 |
5,341,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7270:Arid1b
|
UTSW |
17 |
5,046,318 (GRCm39) |
missense |
unknown |
|
|
R7514:Arid1b
|
UTSW |
17 |
5,391,989 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7519:Arid1b
|
UTSW |
17 |
5,046,128 (GRCm39) |
small insertion |
probably benign |
|
|
R7519:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,392,865 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7521:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,046,135 (GRCm39) |
small insertion |
probably benign |
|
|
R7616:Arid1b
|
UTSW |
17 |
5,045,661 (GRCm39) |
missense |
unknown |
|
|
R7654:Arid1b
|
UTSW |
17 |
5,341,360 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7711:Arid1b
|
UTSW |
17 |
5,387,095 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7828:Arid1b
|
UTSW |
17 |
5,147,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7864:Arid1b
|
UTSW |
17 |
5,392,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7998:Arid1b
|
UTSW |
17 |
5,377,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8105:Arid1b
|
UTSW |
17 |
5,341,518 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8260:Arid1b
|
UTSW |
17 |
5,382,788 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8374:Arid1b
|
UTSW |
17 |
5,392,919 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8779:Arid1b
|
UTSW |
17 |
5,391,809 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8801:Arid1b
|
UTSW |
17 |
5,387,103 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8894:Arid1b
|
UTSW |
17 |
5,377,668 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8982:Arid1b
|
UTSW |
17 |
5,293,316 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9034:Arid1b
|
UTSW |
17 |
5,387,180 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9272:Arid1b
|
UTSW |
17 |
5,386,879 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9300:Arid1b
|
UTSW |
17 |
5,293,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Arid1b
|
UTSW |
17 |
5,045,584 (GRCm39) |
missense |
unknown |
|
|
R9481:Arid1b
|
UTSW |
17 |
5,369,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9493:Arid1b
|
UTSW |
17 |
5,046,423 (GRCm39) |
missense |
unknown |
|
|
R9512:Arid1b
|
UTSW |
17 |
5,391,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9548:Arid1b
|
UTSW |
17 |
5,385,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF007:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,871 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF028:Arid1b
|
UTSW |
17 |
5,045,873 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Arid1b
|
UTSW |
17 |
5,045,860 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF045:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
RF046:Arid1b
|
UTSW |
17 |
5,045,865 (GRCm39) |
small insertion |
probably benign |
|
|
RF058:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
X0023:Arid1b
|
UTSW |
17 |
5,392,668 (GRCm39) |
missense |
probably benign |
0.39 |
|
X0027:Arid1b
|
UTSW |
17 |
5,392,647 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Arid1b
|
UTSW |
17 |
5,046,603 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTTTATCGAACCTTGCCCAG -3'
(R):5'- ACAGCCAGTTATATGTGACCCTC -3'
Sequencing Primer
(F):5'- CGAGGGCAATAGCTGTGC -3'
(R):5'- GCCAGTTATATGTGACCCTCTAATG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation