Incidental Mutation 'R4654:Tnrc6c'
| ID |
351564 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnrc6c
|
| Ensembl Gene |
ENSMUSG00000025571 |
| Gene Name |
trinucleotide repeat containing 6C |
| Synonyms |
9930033H14Rik |
| MMRRC Submission |
041914-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4654 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
117545115-117654265 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 117611797 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 145
(V145A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101951
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026658]
[ENSMUST00000106344]
[ENSMUST00000138299]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026658
AA Change: V145A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000026658
Gene: ENSMUSG00000025571
AA Change: V145A
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106344
AA Change: V145A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000101951
Gene: ENSMUSG00000025571
AA Change: V145A
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
37 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
248 |
257 |
N/A |
INTRINSIC |
|
low complexity region
|
298 |
318 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
457 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
472 |
573 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
594 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
632 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
639 |
704 |
5.49e-5 |
PROSPERO |
|
internal_repeat_1
|
799 |
902 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
964 |
981 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
991 |
1051 |
5.49e-5 |
PROSPERO |
|
low complexity region
|
1063 |
1079 |
N/A |
INTRINSIC |
|
low complexity region
|
1111 |
1125 |
N/A |
INTRINSIC |
|
UBA
|
1145 |
1182 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1232 |
1459 |
6.8e-77 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1468 |
1646 |
4.1e-75 |
PFAM |
|
Pfam:TNRC6-PABC_bdg
|
1643 |
1722 |
3.7e-33 |
PFAM |
|
RRM
|
1725 |
1792 |
1.81e-2 |
SMART |
|
low complexity region
|
1813 |
1823 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138299
|
| SMART Domains |
Protein: ENSMUSP00000115221
Gene: ENSMUSG00000025571
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
88 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
138 |
158 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
248 |
N/A |
INTRINSIC |
|
low complexity region
|
280 |
297 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
312 |
413 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
434 |
454 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
472 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
639 |
742 |
9.45e-5 |
PROSPERO |
|
low complexity region
|
804 |
821 |
N/A |
INTRINSIC |
|
low complexity region
|
903 |
919 |
N/A |
INTRINSIC |
|
low complexity region
|
951 |
965 |
N/A |
INTRINSIC |
|
UBA
|
985 |
1022 |
3.68e-4 |
SMART |
|
Pfam:M_domain
|
1036 |
1293 |
1.7e-53 |
PFAM |
|
low complexity region
|
1397 |
1406 |
N/A |
INTRINSIC |
|
PDB:3KTP|B
|
1422 |
1443 |
7e-7 |
PDB |
|
low complexity region
|
1507 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1531 |
1552 |
N/A |
INTRINSIC |
|
RRM
|
1557 |
1624 |
1.81e-2 |
SMART |
|
low complexity region
|
1645 |
1655 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141115
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.2%
|
| Validation Efficiency |
97% (98/101) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele exhibit complete neonatal lethality with cyanosis, respiratory distress and thickened mesenchyme in air sacs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam3 |
A |
T |
8: 25,193,819 (GRCm39) |
C398S |
probably damaging |
Het |
| Adamts10 |
A |
G |
17: 33,756,304 (GRCm39) |
K316E |
possibly damaging |
Het |
| Ap1m1 |
T |
C |
8: 73,006,717 (GRCm39) |
F238L |
possibly damaging |
Het |
| Aph1a |
T |
A |
3: 95,803,088 (GRCm39) |
D180E |
probably benign |
Het |
| Atp9b |
A |
G |
18: 80,935,093 (GRCm39) |
F201L |
probably benign |
Het |
| Btbd9 |
A |
C |
17: 30,704,561 (GRCm39) |
|
probably benign |
Het |
| C2cd5 |
T |
C |
6: 142,975,910 (GRCm39) |
T768A |
probably benign |
Het |
| Casq1 |
C |
T |
1: 172,037,965 (GRCm39) |
|
probably benign |
Het |
| Cimap2 |
C |
A |
4: 106,467,612 (GRCm39) |
M341I |
probably benign |
Het |
| Cltc |
A |
T |
11: 86,617,196 (GRCm39) |
M351K |
probably benign |
Het |
| Cnp |
A |
G |
11: 100,469,877 (GRCm39) |
E271G |
possibly damaging |
Het |
| Col22a1 |
T |
C |
15: 71,845,544 (GRCm39) |
D406G |
possibly damaging |
Het |
| Cylc2 |
T |
C |
4: 51,228,279 (GRCm39) |
S117P |
probably benign |
Het |
| Cyp2b13 |
T |
C |
7: 25,761,072 (GRCm39) |
L43P |
probably damaging |
Het |
| Cyp3a16 |
A |
G |
5: 145,373,267 (GRCm39) |
V500A |
probably benign |
Het |
| Dclk2 |
T |
C |
3: 86,743,683 (GRCm39) |
D262G |
probably damaging |
Het |
| Dcun1d3 |
A |
C |
7: 119,458,742 (GRCm39) |
Y98D |
probably damaging |
Het |
| Ddx39b |
A |
G |
17: 35,472,464 (GRCm39) |
*429W |
probably null |
Het |
| Dennd5b |
T |
C |
6: 148,908,335 (GRCm39) |
N986S |
probably damaging |
Het |
| Dipk1a |
T |
C |
5: 108,057,982 (GRCm39) |
|
probably null |
Het |
| Dusp9 |
G |
A |
X: 72,684,378 (GRCm39) |
R182Q |
probably benign |
Het |
| Ecpas |
A |
T |
4: 58,834,523 (GRCm39) |
I785N |
possibly damaging |
Het |
| Edil3 |
A |
G |
13: 89,437,589 (GRCm39) |
K397E |
probably damaging |
Het |
| Ehd1 |
T |
C |
19: 6,326,994 (GRCm39) |
|
probably benign |
Het |
| Fam13a |
A |
T |
6: 58,964,152 (GRCm39) |
H93Q |
probably benign |
Het |
| Farp1 |
T |
C |
14: 121,513,716 (GRCm39) |
I837T |
possibly damaging |
Het |
| Fbxl5 |
T |
A |
5: 43,922,771 (GRCm39) |
I216F |
probably damaging |
Het |
| Gadl1 |
G |
A |
9: 115,770,408 (GRCm39) |
E74K |
probably damaging |
Het |
| Gnpnat1 |
A |
G |
14: 45,618,436 (GRCm39) |
V122A |
probably damaging |
Het |
| Hdac10 |
C |
T |
15: 89,011,036 (GRCm39) |
|
probably benign |
Het |
| Heatr5b |
T |
C |
17: 79,128,130 (GRCm39) |
S502G |
possibly damaging |
Het |
| Hr |
C |
A |
14: 70,801,013 (GRCm39) |
A695E |
probably damaging |
Het |
| Ift80 |
A |
T |
3: 68,825,870 (GRCm39) |
I490N |
possibly damaging |
Het |
| Ipo11 |
A |
G |
13: 106,970,692 (GRCm39) |
|
probably benign |
Het |
| Iqch |
T |
G |
9: 63,432,195 (GRCm39) |
Y400S |
probably damaging |
Het |
| Jag2 |
C |
T |
12: 112,877,266 (GRCm39) |
D702N |
probably benign |
Het |
| Kiss1r |
T |
A |
10: 79,757,624 (GRCm39) |
L326Q |
probably damaging |
Het |
| Lrrc42 |
A |
T |
4: 107,104,746 (GRCm39) |
I73N |
probably damaging |
Het |
| Lrrc55 |
C |
T |
2: 85,026,880 (GRCm39) |
G48D |
possibly damaging |
Het |
| Lrrk2 |
T |
C |
15: 91,649,884 (GRCm39) |
S1674P |
probably damaging |
Het |
| Mctp2 |
A |
G |
7: 71,739,942 (GRCm39) |
L816P |
probably damaging |
Het |
| Mipol1 |
A |
T |
12: 57,352,918 (GRCm39) |
T86S |
probably benign |
Het |
| Mkrn3 |
C |
T |
7: 62,069,452 (GRCm39) |
R113H |
probably damaging |
Het |
| Mmp1b |
A |
G |
9: 7,370,849 (GRCm39) |
V302A |
probably benign |
Het |
| Msc |
A |
T |
1: 14,826,053 (GRCm39) |
|
probably null |
Het |
| Msmo1 |
C |
A |
8: 65,180,888 (GRCm39) |
V9L |
probably benign |
Het |
| Nbeal2 |
G |
A |
9: 110,461,072 (GRCm39) |
R1630C |
probably damaging |
Het |
| Nlgn1 |
C |
T |
3: 26,187,850 (GRCm39) |
V12I |
possibly damaging |
Het |
| Npas3 |
T |
C |
12: 54,108,915 (GRCm39) |
|
probably null |
Het |
| Nr2e3 |
A |
G |
9: 59,856,355 (GRCm39) |
|
probably benign |
Het |
| Oca2 |
C |
T |
7: 55,978,560 (GRCm39) |
A576V |
probably benign |
Het |
| Or5b21 |
T |
A |
19: 12,839,596 (GRCm39) |
C152* |
probably null |
Het |
| Or6d12 |
T |
C |
6: 116,493,409 (GRCm39) |
Y224H |
probably damaging |
Het |
| Or6z7 |
T |
C |
7: 6,484,045 (GRCm39) |
T37A |
probably benign |
Het |
| Parp6 |
A |
G |
9: 59,548,383 (GRCm39) |
|
probably null |
Het |
| Pate13 |
T |
A |
9: 35,820,287 (GRCm39) |
C4S |
probably damaging |
Het |
| Phlpp1 |
A |
T |
1: 106,267,231 (GRCm39) |
M715L |
probably benign |
Het |
| Pi4k2a |
G |
A |
19: 42,101,544 (GRCm39) |
|
probably null |
Het |
| Pik3ap1 |
A |
G |
19: 41,316,348 (GRCm39) |
S305P |
probably damaging |
Het |
| Plcg2 |
G |
A |
8: 118,231,054 (GRCm39) |
M45I |
probably benign |
Het |
| Ppm1m |
A |
T |
9: 106,073,601 (GRCm39) |
L317H |
probably damaging |
Het |
| Ppp1r21 |
T |
G |
17: 88,866,227 (GRCm39) |
M341R |
probably benign |
Het |
| Prdx3 |
A |
G |
19: 60,853,674 (GRCm39) |
V217A |
possibly damaging |
Het |
| Ptk2b |
A |
G |
14: 66,400,496 (GRCm39) |
V773A |
possibly damaging |
Het |
| Raly |
T |
C |
2: 154,699,376 (GRCm39) |
V60A |
probably damaging |
Het |
| Reps1 |
A |
G |
10: 17,990,148 (GRCm39) |
D420G |
probably damaging |
Het |
| Rev1 |
A |
T |
1: 38,118,337 (GRCm39) |
|
probably benign |
Het |
| Rgs2 |
T |
G |
1: 143,878,650 (GRCm39) |
|
probably benign |
Het |
| Rlf |
G |
T |
4: 121,007,798 (GRCm39) |
T394K |
probably benign |
Het |
| Rptn |
A |
T |
3: 93,304,792 (GRCm39) |
R708S |
possibly damaging |
Het |
| Sec23b |
T |
A |
2: 144,414,494 (GRCm39) |
M402K |
probably benign |
Het |
| Skic2 |
A |
G |
17: 35,068,922 (GRCm39) |
C26R |
probably damaging |
Het |
| Slx9 |
T |
C |
10: 77,325,860 (GRCm39) |
M170V |
possibly damaging |
Het |
| Smpd4 |
A |
G |
16: 17,459,992 (GRCm39) |
|
probably benign |
Het |
| Synj2 |
A |
G |
17: 6,063,813 (GRCm39) |
E434G |
probably damaging |
Het |
| Tatdn2 |
T |
A |
6: 113,684,326 (GRCm39) |
F64I |
probably benign |
Het |
| Tex21 |
A |
C |
12: 76,263,860 (GRCm39) |
H177Q |
probably benign |
Het |
| Tln1 |
T |
A |
4: 43,535,954 (GRCm39) |
Q2077L |
probably null |
Het |
| Ttn |
C |
T |
2: 76,616,936 (GRCm39) |
|
probably benign |
Het |
| Uggt2 |
A |
G |
14: 119,269,670 (GRCm39) |
F954S |
possibly damaging |
Het |
| Ugt2a1 |
A |
G |
5: 87,634,083 (GRCm39) |
S175P |
probably damaging |
Het |
| Vcl |
A |
G |
14: 21,035,820 (GRCm39) |
|
probably null |
Het |
| Vegfa |
A |
T |
17: 46,336,176 (GRCm39) |
|
probably benign |
Het |
| Vmn2r68 |
G |
A |
7: 84,882,769 (GRCm39) |
Q328* |
probably null |
Het |
| Vmn2r7 |
A |
G |
3: 64,626,864 (GRCm39) |
Y142H |
probably benign |
Het |
| Wdr17 |
C |
T |
8: 55,134,434 (GRCm39) |
G349R |
probably damaging |
Het |
| Ybx3 |
G |
T |
6: 131,347,290 (GRCm39) |
R282S |
probably damaging |
Het |
| Zfp566 |
T |
C |
7: 29,777,194 (GRCm39) |
H329R |
probably damaging |
Het |
| Zfp786 |
T |
C |
6: 47,797,868 (GRCm39) |
I357V |
probably benign |
Het |
| Zfr2 |
C |
A |
10: 81,087,083 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Tnrc6c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00839:Tnrc6c
|
APN |
11 |
117,605,011 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01013:Tnrc6c
|
APN |
11 |
117,612,855 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL01092:Tnrc6c
|
APN |
11 |
117,612,811 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01383:Tnrc6c
|
APN |
11 |
117,605,083 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01395:Tnrc6c
|
APN |
11 |
117,613,939 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01726:Tnrc6c
|
APN |
11 |
117,640,161 (GRCm39) |
splice site |
probably benign |
|
|
IGL01869:Tnrc6c
|
APN |
11 |
117,646,274 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL02108:Tnrc6c
|
APN |
11 |
117,612,025 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02457:Tnrc6c
|
APN |
11 |
117,613,803 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02612:Tnrc6c
|
APN |
11 |
117,633,826 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02748:Tnrc6c
|
APN |
11 |
117,622,996 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03160:Tnrc6c
|
APN |
11 |
117,640,651 (GRCm39) |
splice site |
probably benign |
|
|
rodion
|
UTSW |
11 |
117,629,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
F5770:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
K3955:Tnrc6c
|
UTSW |
11 |
117,651,564 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0015:Tnrc6c
|
UTSW |
11 |
117,612,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0143:Tnrc6c
|
UTSW |
11 |
117,643,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0277:Tnrc6c
|
UTSW |
11 |
117,630,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0323:Tnrc6c
|
UTSW |
11 |
117,630,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0464:Tnrc6c
|
UTSW |
11 |
117,651,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0699:Tnrc6c
|
UTSW |
11 |
117,613,447 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1015:Tnrc6c
|
UTSW |
11 |
117,612,748 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1201:Tnrc6c
|
UTSW |
11 |
117,612,500 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1297:Tnrc6c
|
UTSW |
11 |
117,624,529 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1560:Tnrc6c
|
UTSW |
11 |
117,650,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1596:Tnrc6c
|
UTSW |
11 |
117,648,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnrc6c
|
UTSW |
11 |
117,651,556 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1892:Tnrc6c
|
UTSW |
11 |
117,605,188 (GRCm39) |
missense |
probably benign |
|
|
R1901:Tnrc6c
|
UTSW |
11 |
117,613,831 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1935:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1936:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1937:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1940:Tnrc6c
|
UTSW |
11 |
117,646,849 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3622:Tnrc6c
|
UTSW |
11 |
117,640,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3711:Tnrc6c
|
UTSW |
11 |
117,613,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3725:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3775:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3776:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3836:Tnrc6c
|
UTSW |
11 |
117,614,055 (GRCm39) |
missense |
probably benign |
0.20 |
|
R3844:Tnrc6c
|
UTSW |
11 |
117,646,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3928:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3929:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3937:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3943:Tnrc6c
|
UTSW |
11 |
117,614,355 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4501:Tnrc6c
|
UTSW |
11 |
117,613,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Tnrc6c
|
UTSW |
11 |
117,633,784 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4511:Tnrc6c
|
UTSW |
11 |
117,633,784 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4765:Tnrc6c
|
UTSW |
11 |
117,633,753 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4824:Tnrc6c
|
UTSW |
11 |
117,613,731 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5004:Tnrc6c
|
UTSW |
11 |
117,611,872 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5094:Tnrc6c
|
UTSW |
11 |
117,611,872 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5130:Tnrc6c
|
UTSW |
11 |
117,629,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5234:Tnrc6c
|
UTSW |
11 |
117,651,555 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5235:Tnrc6c
|
UTSW |
11 |
117,651,555 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5345:Tnrc6c
|
UTSW |
11 |
117,614,113 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5359:Tnrc6c
|
UTSW |
11 |
117,649,731 (GRCm39) |
splice site |
silent |
|
|
R5428:Tnrc6c
|
UTSW |
11 |
117,591,588 (GRCm39) |
start codon destroyed |
probably null |
|
|
R5548:Tnrc6c
|
UTSW |
11 |
117,651,669 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5587:Tnrc6c
|
UTSW |
11 |
117,640,097 (GRCm39) |
nonsense |
probably null |
|
|
R5875:Tnrc6c
|
UTSW |
11 |
117,650,534 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5947:Tnrc6c
|
UTSW |
11 |
117,613,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6135:Tnrc6c
|
UTSW |
11 |
117,626,831 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6354:Tnrc6c
|
UTSW |
11 |
117,640,440 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6389:Tnrc6c
|
UTSW |
11 |
117,613,567 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7027:Tnrc6c
|
UTSW |
11 |
117,624,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7048:Tnrc6c
|
UTSW |
11 |
117,612,800 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7098:Tnrc6c
|
UTSW |
11 |
117,604,952 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7315:Tnrc6c
|
UTSW |
11 |
117,614,354 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7378:Tnrc6c
|
UTSW |
11 |
117,632,606 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7386:Tnrc6c
|
UTSW |
11 |
117,612,780 (GRCm39) |
missense |
probably benign |
|
|
R7515:Tnrc6c
|
UTSW |
11 |
117,632,507 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7665:Tnrc6c
|
UTSW |
11 |
117,611,777 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7755:Tnrc6c
|
UTSW |
11 |
117,648,912 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8679:Tnrc6c
|
UTSW |
11 |
117,604,961 (GRCm39) |
missense |
probably benign |
|
|
R8824:Tnrc6c
|
UTSW |
11 |
117,630,680 (GRCm39) |
splice site |
probably benign |
|
|
R8971:Tnrc6c
|
UTSW |
11 |
117,640,089 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9261:Tnrc6c
|
UTSW |
11 |
117,605,105 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9283:Tnrc6c
|
UTSW |
11 |
117,591,630 (GRCm39) |
missense |
unknown |
|
|
R9342:Tnrc6c
|
UTSW |
11 |
117,630,720 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9633:Tnrc6c
|
UTSW |
11 |
117,638,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Tnrc6c
|
UTSW |
11 |
117,623,136 (GRCm39) |
missense |
probably benign |
|
|
V7580:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7581:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7582:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V7583:Tnrc6c
|
UTSW |
11 |
117,614,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnrc6c
|
UTSW |
11 |
117,623,003 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGGAAACATTCGGGGTTTTAAGG -3'
(R):5'- TTGGAGGCAGAGTCAGTGTC -3'
Sequencing Primer
(F):5'- CCCAGGAACTTAGATGTGCTG -3'
(R):5'- CGGTAGGACATTCTGAGGCAGATTC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation