Mutagenetix > Incidental Mutation

Incidental Mutation 'R8692:Dnah7a'

668407

Institutional Source

Beutler Lab

Gene Symbol

Dnah7a

Ensembl Gene

ENSMUSG00000096141

Gene Name

dynein, axonemal, heavy chain 7A

Synonyms

Dnahc7, LOC381341, Dnahc7a

MMRRC Submission

068546-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.147) question?

Stock #

R8692 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

53436165-53745943 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 53472175 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Alanine at position 3531 (S3531A)

Ref Sequence

ENSEMBL: ENSMUSP00000092571 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094964]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000094964
AA Change: S3531A

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000092571
Gene: ENSMUSG00000096141
AA Change: S3531A

Domain	Start	End	E-Value	Type
low complexity region	2	15	N/A	INTRINSIC
coiled coil region	504	537	N/A	INTRINSIC
Pfam:DHC_N2	756	1165	3.1e-149	PFAM
AAA	1320	1459	2.46e-1	SMART
Blast:AAA	1601	1879	1e-87	BLAST
AAA	1968	2116	5.39e-2	SMART
Pfam:AAA_8	2303	2574	6.9e-75	PFAM
Pfam:MT	2586	2936	2.1e-55	PFAM
Pfam:AAA_9	2957	3182	1.3e-98	PFAM
Pfam:Dynein_heavy	3318	4020	2.3e-287	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.5%
20x: 98.1%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca12	A	C	1: 71,327,874 (GRCm39)	I1402S	probably damaging	Het
Abca9	T	C	11: 110,032,409 (GRCm39)	D736G	probably benign	Het
Acy1	T	C	9: 106,310,377 (GRCm39)	E377G	probably damaging	Het
Apob	G	A	12: 8,058,270 (GRCm39)	V2251M	probably damaging	Het
Arhgap23	C	A	11: 97,345,322 (GRCm39)	T657K	probably damaging	Het
Cabin1	T	C	10: 75,587,410 (GRCm39)	K129R	probably benign	Het
Cdh24	A	T	14: 54,875,793 (GRCm39)	F259I	probably benign	Het
Cops6	A	G	5: 138,162,083 (GRCm39)	N307S	probably benign	Het
Cyp4a31	G	A	4: 115,423,769 (GRCm39)	V143M	probably damaging	Het
Deaf1	A	T	7: 140,877,444 (GRCm39)	I561K	probably benign	Het
Dnajc14	T	A	10: 128,642,900 (GRCm39)	I274N	probably damaging	Het
Dnmt1	A	G	9: 20,853,077 (GRCm39)	L48S	probably damaging	Het
Efna4	A	T	3: 89,242,549 (GRCm39)	I115N	probably damaging	Het
Ermp1	T	A	19: 29,594,093 (GRCm39)	L692F	probably benign	Het
Fcho2	GT	G	13: 98,882,382 (GRCm39)		probably null	Het
Fcsk	A	T	8: 111,615,722 (GRCm39)	C536S	probably benign	Het
Fermt2	A	T	14: 45,742,099 (GRCm39)	C82*	probably null	Het
Gabra6	G	T	11: 42,210,537 (GRCm39)	D61E	probably damaging	Het
Gdpd4	T	A	7: 97,690,140 (GRCm39)	S611T	probably benign	Het
Gm10800	AAGAAAACTGAAAATCAT	A	2: 98,497,379 (GRCm39)		probably benign	Het
Gm17430	G	A	18: 9,726,336 (GRCm39)	A112V	probably benign	Het
Gm2381	A	T	7: 42,472,071 (GRCm39)	L2Q	probably damaging	Het
Hif3a	A	T	7: 16,788,701 (GRCm39)	L90Q	probably benign	Het
Irf3	C	T	7: 44,649,889 (GRCm39)	Q168*	probably null	Het
Krt82	T	G	15: 101,456,828 (GRCm39)	D184A	possibly damaging	Het
Lgals4	C	T	7: 28,540,921 (GRCm39)	R282C	probably damaging	Het
Lrrc49	A	G	9: 60,594,445 (GRCm39)	S28P	probably damaging	Het
Mfsd11	T	A	11: 116,752,443 (GRCm39)	N197K	probably benign	Het
Mindy1	A	G	3: 95,199,587 (GRCm39)	D243G	probably damaging	Het
Mphosph9	A	T	5: 124,450,875 (GRCm39)	W299R	probably damaging	Het
Mst1r	G	T	9: 107,792,050 (GRCm39)	R862L	possibly damaging	Het
Nasp	T	A	4: 116,469,280 (GRCm39)		probably null	Het
Ncapg2	T	C	12: 116,414,049 (GRCm39)	I1073T	probably damaging	Het
Nek2	A	T	1: 191,554,745 (GRCm39)	K152N	probably benign	Het
Neurod2	T	C	11: 98,218,960 (GRCm39)	E68G	probably benign	Het
Or1j4	A	T	2: 36,740,096 (GRCm39)	I13F	probably benign	Het
Or2w3b	T	C	11: 58,623,595 (GRCm39)	Y132C	probably damaging	Het
P4ha3	T	A	7: 99,955,228 (GRCm39)	I361N	probably damaging	Het
Pcdh15	T	A	10: 74,289,805 (GRCm39)	S875T	possibly damaging	Het
Pde7b	G	T	10: 20,423,639 (GRCm39)	P79Q	probably benign	Het
Phb2	G	A	6: 124,692,097 (GRCm39)	A228T	probably damaging	Het
Piezo2	A	T	18: 63,225,971 (GRCm39)	C888*	probably null	Het
Pkhd1	A	T	1: 20,462,374 (GRCm39)	L2060Q	probably damaging	Het
Pms1	T	C	1: 53,246,052 (GRCm39)	M496V	probably benign	Het
Ppfibp1	C	T	6: 146,892,013 (GRCm39)	T91I	probably benign	Het
Ppp1r9b	T	C	11: 94,891,077 (GRCm39)	L557P	probably damaging	Het
Ppp2r5c	G	T	12: 110,489,032 (GRCm39)	V68L	probably benign	Het
Qrfp	T	A	2: 31,698,797 (GRCm39)	H45L	probably benign	Het
Rasgrp1	G	A	2: 117,115,353 (GRCm39)	T745I	probably damaging	Het
Rnf144a	G	A	12: 26,370,972 (GRCm39)	T163I	probably benign	Het
Sbsn	A	T	7: 30,451,522 (GRCm39)	H179L	unknown	Het
Simc1	G	A	13: 54,673,193 (GRCm39)	V514I	probably benign	Het
Slc35d1	A	G	4: 103,047,051 (GRCm39)	M249T		Het
Slfn4	T	A	11: 83,079,709 (GRCm39)	H466Q	possibly damaging	Het
Stab2	A	T	10: 86,808,794 (GRCm39)	C172S	probably damaging	Het
Tanc1	T	C	2: 59,673,989 (GRCm39)	I1698T	probably benign	Het
Tenm4	C	T	7: 96,555,148 (GRCm39)	P2618S	probably benign	Het
Tiam2	A	C	17: 3,479,082 (GRCm39)	D605A	probably damaging	Het
Tmed4	A	T	11: 6,223,822 (GRCm39)	D151E	probably benign	Het
Trim62	A	T	4: 128,794,465 (GRCm39)	I211F	possibly damaging	Het
Ttpa	A	G	4: 20,008,585 (GRCm39)	D49G	probably benign	Het
Usf3	T	C	16: 44,040,103 (GRCm39)	S1528P	probably benign	Het
Usp34	C	T	11: 23,379,325 (GRCm39)	T1991I		Het
Vash1	G	A	12: 86,735,863 (GRCm39)	V250M	possibly damaging	Het
Vmn1r199	T	C	13: 22,567,809 (GRCm39)	*368Q	probably null	Het
Vmn1r74	A	G	7: 11,580,972 (GRCm39)	T91A	probably benign	Het
Vmn1r8	T	C	6: 57,013,557 (GRCm39)	F203L	probably benign	Het
Vmn2r13	G	T	5: 109,319,514 (GRCm39)	Q489K	probably benign	Het
Vmn2r-ps158	G	T	7: 42,697,108 (GRCm39)	A722S	probably benign	Het
Zfp385b	A	T	2: 77,549,971 (GRCm39)	V38E	probably damaging	Het
Zfp820	A	G	17: 22,037,876 (GRCm39)	I484T	probably benign	Het

Other mutations in Dnah7a

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00479:Dnah7a	APN	1	53,458,843 (GRCm39)	missense	probably damaging	0.99
IGL00510:Dnah7a	APN	1	53,540,701 (GRCm39)	missense	probably damaging	1.00
IGL00545:Dnah7a	APN	1	53,496,905 (GRCm39)	missense	possibly damaging	0.87
IGL01320:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01322:Dnah7a	APN	1	53,473,205 (GRCm39)	missense	probably benign	0.32
IGL01357:Dnah7a	APN	1	53,701,540 (GRCm39)	missense	probably benign
IGL01417:Dnah7a	APN	1	53,623,759 (GRCm39)	missense	probably benign	0.01
IGL01508:Dnah7a	APN	1	53,666,231 (GRCm39)	missense	probably benign	0.00
IGL01511:Dnah7a	APN	1	53,458,754 (GRCm39)	missense	probably damaging	1.00
IGL01545:Dnah7a	APN	1	53,557,941 (GRCm39)	missense	probably benign
IGL01575:Dnah7a	APN	1	53,466,979 (GRCm39)	splice site	probably benign
IGL01667:Dnah7a	APN	1	53,586,451 (GRCm39)	missense	probably damaging	1.00
IGL01712:Dnah7a	APN	1	53,462,429 (GRCm39)	missense	probably benign	0.23
IGL01824:Dnah7a	APN	1	53,543,429 (GRCm39)	missense	probably benign
IGL01829:Dnah7a	APN	1	53,657,227 (GRCm39)	missense	possibly damaging	0.64
IGL01861:Dnah7a	APN	1	53,623,608 (GRCm39)	splice site	probably benign
IGL01861:Dnah7a	APN	1	53,679,508 (GRCm39)	missense	probably benign	0.01
IGL01984:Dnah7a	APN	1	53,741,174 (GRCm39)	splice site	probably null
IGL02056:Dnah7a	APN	1	53,543,501 (GRCm39)	missense	probably benign	0.17
IGL02069:Dnah7a	APN	1	53,601,053 (GRCm39)	splice site	probably benign
IGL02072:Dnah7a	APN	1	53,644,986 (GRCm39)	missense	probably damaging	1.00
IGL02110:Dnah7a	APN	1	53,450,739 (GRCm39)	missense	possibly damaging	0.52
IGL02120:Dnah7a	APN	1	53,534,876 (GRCm39)	missense	possibly damaging	0.46
IGL02128:Dnah7a	APN	1	53,476,672 (GRCm39)	missense	probably damaging	1.00
IGL02135:Dnah7a	APN	1	53,662,632 (GRCm39)	missense	probably benign	0.01
IGL02151:Dnah7a	APN	1	53,512,023 (GRCm39)	missense	probably benign	0.08
IGL02156:Dnah7a	APN	1	53,458,882 (GRCm39)	missense	probably benign	0.27
IGL02270:Dnah7a	APN	1	53,512,052 (GRCm39)	missense	possibly damaging	0.93
IGL02282:Dnah7a	APN	1	53,682,669 (GRCm39)	missense	possibly damaging	0.93
IGL02328:Dnah7a	APN	1	53,564,096 (GRCm39)	critical splice donor site	probably null
IGL02370:Dnah7a	APN	1	53,674,556 (GRCm39)	missense	probably benign	0.00
IGL02420:Dnah7a	APN	1	53,725,702 (GRCm39)	missense	probably benign
IGL02458:Dnah7a	APN	1	53,657,487 (GRCm39)	nonsense	probably null
IGL02489:Dnah7a	APN	1	53,686,481 (GRCm39)	missense	possibly damaging	0.94
IGL02554:Dnah7a	APN	1	53,657,205 (GRCm39)	missense	possibly damaging	0.93
IGL02578:Dnah7a	APN	1	53,472,074 (GRCm39)	missense	probably benign	0.00
IGL02646:Dnah7a	APN	1	53,564,194 (GRCm39)	missense	probably damaging	0.99
IGL02675:Dnah7a	APN	1	53,543,183 (GRCm39)	missense	possibly damaging	0.96
IGL02688:Dnah7a	APN	1	53,483,631 (GRCm39)	missense	possibly damaging	0.93
IGL02858:Dnah7a	APN	1	53,512,118 (GRCm39)	splice site	probably benign
IGL02874:Dnah7a	APN	1	53,644,973 (GRCm39)	missense	possibly damaging	0.70
IGL02887:Dnah7a	APN	1	53,561,519 (GRCm39)	missense	possibly damaging	0.46
IGL02894:Dnah7a	APN	1	53,616,487 (GRCm39)	missense	probably benign	0.27
IGL02926:Dnah7a	APN	1	53,535,109 (GRCm39)	missense	possibly damaging	0.64
IGL03113:Dnah7a	APN	1	53,472,163 (GRCm39)	missense	possibly damaging	0.64
IGL03156:Dnah7a	APN	1	53,644,983 (GRCm39)	missense	probably damaging	0.97
IGL03195:Dnah7a	APN	1	53,458,766 (GRCm39)	missense	probably damaging	1.00
IGL03209:Dnah7a	APN	1	53,725,773 (GRCm39)	splice site	probably benign
IGL03214:Dnah7a	APN	1	53,561,368 (GRCm39)	critical splice donor site	probably null
IGL03242:Dnah7a	APN	1	53,659,882 (GRCm39)	missense	probably benign	0.02
IGL03251:Dnah7a	APN	1	53,686,433 (GRCm39)	missense	probably benign
IGL03265:Dnah7a	APN	1	53,568,007 (GRCm39)	missense	probably benign
IGL03277:Dnah7a	APN	1	53,669,481 (GRCm39)	missense	probably benign	0.00
IGL03278:Dnah7a	APN	1	53,536,124 (GRCm39)	missense	probably benign	0.07
IGL03356:Dnah7a	APN	1	53,543,093 (GRCm39)	missense	probably benign	0.01
PIT4378001:Dnah7a	UTSW	1	53,570,362 (GRCm39)	missense	probably damaging	0.99
R0046:Dnah7a	UTSW	1	53,496,033 (GRCm39)	splice site	probably null
R0051:Dnah7a	UTSW	1	53,560,245 (GRCm39)	splice site	probably benign
R0082:Dnah7a	UTSW	1	53,557,867 (GRCm39)	missense	probably damaging	1.00
R0111:Dnah7a	UTSW	1	53,507,843 (GRCm39)	missense	probably benign	0.03
R0122:Dnah7a	UTSW	1	53,436,301 (GRCm39)	missense	probably damaging	1.00
R0245:Dnah7a	UTSW	1	53,540,685 (GRCm39)	missense	probably damaging	1.00
R0278:Dnah7a	UTSW	1	53,543,305 (GRCm39)	missense	probably benign	0.00
R0309:Dnah7a	UTSW	1	53,444,849 (GRCm39)	missense	probably damaging	0.97
R0334:Dnah7a	UTSW	1	53,472,213 (GRCm39)	missense	possibly damaging	0.61
R0392:Dnah7a	UTSW	1	53,543,357 (GRCm39)	missense	probably damaging	0.97
R0452:Dnah7a	UTSW	1	53,644,978 (GRCm39)	missense	probably benign	0.00
R0511:Dnah7a	UTSW	1	53,536,285 (GRCm39)	missense	probably benign
R0576:Dnah7a	UTSW	1	53,675,246 (GRCm39)	missense	probably benign	0.12
R0592:Dnah7a	UTSW	1	53,495,771 (GRCm39)	missense	possibly damaging	0.91
R0628:Dnah7a	UTSW	1	53,536,264 (GRCm39)	missense	probably benign	0.18
R0689:Dnah7a	UTSW	1	53,659,840 (GRCm39)	nonsense	probably null
R0735:Dnah7a	UTSW	1	53,583,670 (GRCm39)	missense	possibly damaging	0.70
R0800:Dnah7a	UTSW	1	53,604,855 (GRCm39)	missense	probably damaging	1.00
R0829:Dnah7a	UTSW	1	53,543,238 (GRCm39)	missense	probably benign	0.07
R0842:Dnah7a	UTSW	1	53,540,833 (GRCm39)	missense	possibly damaging	0.88
R0879:Dnah7a	UTSW	1	53,467,019 (GRCm39)	missense	possibly damaging	0.85
R1331:Dnah7a	UTSW	1	53,507,828 (GRCm39)	missense	probably damaging	0.99
R1418:Dnah7a	UTSW	1	53,686,395 (GRCm39)	splice site	probably benign
R1421:Dnah7a	UTSW	1	53,580,032 (GRCm39)	splice site	probably benign
R1445:Dnah7a	UTSW	1	53,567,956 (GRCm39)	missense	probably benign	0.02
R1473:Dnah7a	UTSW	1	53,535,173 (GRCm39)	missense	probably benign	0.00
R1538:Dnah7a	UTSW	1	53,535,148 (GRCm39)	missense	possibly damaging	0.71
R1742:Dnah7a	UTSW	1	53,495,843 (GRCm39)	missense	probably benign	0.39
R1754:Dnah7a	UTSW	1	53,601,059 (GRCm39)	critical splice donor site	probably null
R1754:Dnah7a	UTSW	1	53,543,344 (GRCm39)	missense	probably benign	0.18
R1773:Dnah7a	UTSW	1	53,472,046 (GRCm39)	splice site	probably null
R1779:Dnah7a	UTSW	1	53,616,382 (GRCm39)	missense	probably benign
R1816:Dnah7a	UTSW	1	53,670,901 (GRCm39)	splice site	probably benign
R1817:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1818:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1819:Dnah7a	UTSW	1	53,598,307 (GRCm39)	missense	probably benign
R1873:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1875:Dnah7a	UTSW	1	53,495,691 (GRCm39)	splice site	probably benign
R1884:Dnah7a	UTSW	1	53,580,159 (GRCm39)	missense	probably damaging	0.99
R1902:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1903:Dnah7a	UTSW	1	53,574,637 (GRCm39)	missense	probably damaging	1.00
R1908:Dnah7a	UTSW	1	53,670,721 (GRCm39)	missense	probably benign
R1959:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1960:Dnah7a	UTSW	1	53,724,142 (GRCm39)	missense	probably benign	0.00
R1985:Dnah7a	UTSW	1	53,543,093 (GRCm39)	missense	probably benign	0.01
R1992:Dnah7a	UTSW	1	53,621,835 (GRCm39)	missense	possibly damaging	0.91
R2037:Dnah7a	UTSW	1	53,621,741 (GRCm39)	missense	probably benign	0.00
R2074:Dnah7a	UTSW	1	53,496,855 (GRCm39)	missense	probably benign	0.45
R2076:Dnah7a	UTSW	1	53,542,968 (GRCm39)	missense	probably benign	0.01
R2124:Dnah7a	UTSW	1	53,536,101 (GRCm39)	missense	possibly damaging	0.58
R2191:Dnah7a	UTSW	1	53,645,034 (GRCm39)	missense	possibly damaging	0.54
R2211:Dnah7a	UTSW	1	53,518,932 (GRCm39)	missense	probably benign	0.21
R2220:Dnah7a	UTSW	1	53,560,333 (GRCm39)	missense	probably benign
R2355:Dnah7a	UTSW	1	53,621,661 (GRCm39)	missense	probably benign	0.00
R2495:Dnah7a	UTSW	1	53,645,040 (GRCm39)	missense	probably damaging	1.00
R2901:Dnah7a	UTSW	1	53,467,031 (GRCm39)	missense	probably damaging	0.99
R2911:Dnah7a	UTSW	1	53,466,983 (GRCm39)	critical splice donor site	probably null
R2993:Dnah7a	UTSW	1	53,542,713 (GRCm39)	missense	probably damaging	1.00
R3522:Dnah7a	UTSW	1	53,657,275 (GRCm39)	missense	probably damaging	1.00
R3683:Dnah7a	UTSW	1	53,483,675 (GRCm39)	missense	probably benign
R3723:Dnah7a	UTSW	1	53,486,505 (GRCm39)	missense	probably benign	0.04
R3847:Dnah7a	UTSW	1	53,540,815 (GRCm39)	missense	probably benign	0.01
R4002:Dnah7a	UTSW	1	53,670,840 (GRCm39)	missense	probably benign
R4009:Dnah7a	UTSW	1	53,564,164 (GRCm39)	missense	probably damaging	1.00
R4063:Dnah7a	UTSW	1	53,464,376 (GRCm39)	missense	probably benign
R4193:Dnah7a	UTSW	1	53,486,493 (GRCm39)	missense	probably benign	0.00
R4236:Dnah7a	UTSW	1	53,486,524 (GRCm39)	missense	probably benign	0.00
R4399:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R4469:Dnah7a	UTSW	1	53,483,685 (GRCm39)	missense	probably benign	0.01
R4494:Dnah7a	UTSW	1	53,488,197 (GRCm39)	missense	probably benign	0.01
R4569:Dnah7a	UTSW	1	53,450,818 (GRCm39)	missense	probably benign	0.01
R4609:Dnah7a	UTSW	1	53,495,816 (GRCm39)	missense	possibly damaging	0.80
R4632:Dnah7a	UTSW	1	53,467,110 (GRCm39)	missense	probably damaging	0.97
R4703:Dnah7a	UTSW	1	53,486,476 (GRCm39)	critical splice donor site	probably null
R4781:Dnah7a	UTSW	1	53,464,367 (GRCm39)	missense	probably benign	0.28
R4854:Dnah7a	UTSW	1	53,745,888 (GRCm39)	utr 5 prime	probably benign
R4932:Dnah7a	UTSW	1	53,542,737 (GRCm39)	missense	possibly damaging	0.90
R4976:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5000:Dnah7a	UTSW	1	53,606,201 (GRCm39)	missense	probably damaging	1.00
R5023:Dnah7a	UTSW	1	53,686,407 (GRCm39)	nonsense	probably null
R5026:Dnah7a	UTSW	1	53,701,657 (GRCm39)	missense	probably damaging	0.99
R5050:Dnah7a	UTSW	1	53,536,255 (GRCm39)	missense	probably benign	0.01
R5119:Dnah7a	UTSW	1	53,737,851 (GRCm39)	missense	probably benign
R5151:Dnah7a	UTSW	1	53,659,929 (GRCm39)	missense	probably benign	0.00
R5155:Dnah7a	UTSW	1	53,682,654 (GRCm39)	missense	probably benign	0.01
R5180:Dnah7a	UTSW	1	53,462,446 (GRCm39)	missense	probably damaging	0.97
R5228:Dnah7a	UTSW	1	53,476,768 (GRCm39)	critical splice acceptor site	probably null
R5237:Dnah7a	UTSW	1	53,486,690 (GRCm39)	splice site	probably null
R5267:Dnah7a	UTSW	1	53,518,851 (GRCm39)	missense	probably damaging	1.00
R5334:Dnah7a	UTSW	1	53,542,805 (GRCm39)	missense	probably benign	0.00
R5358:Dnah7a	UTSW	1	53,586,331 (GRCm39)	missense	probably damaging	1.00
R5401:Dnah7a	UTSW	1	53,670,812 (GRCm39)	missense	probably benign	0.01
R5412:Dnah7a	UTSW	1	53,674,503 (GRCm39)	missense	probably benign
R5496:Dnah7a	UTSW	1	53,496,927 (GRCm39)	missense	probably benign
R5531:Dnah7a	UTSW	1	53,458,907 (GRCm39)	missense	possibly damaging	0.50
R5536:Dnah7a	UTSW	1	53,464,412 (GRCm39)	missense	probably benign
R5543:Dnah7a	UTSW	1	53,543,228 (GRCm39)	missense	probably damaging	1.00
R5597:Dnah7a	UTSW	1	53,573,611 (GRCm39)	missense	probably benign	0.00
R5609:Dnah7a	UTSW	1	53,621,753 (GRCm39)	missense	probably benign	0.03
R5643:Dnah7a	UTSW	1	53,444,866 (GRCm39)	missense	probably benign
R5644:Dnah7a	UTSW	1	53,580,138 (GRCm39)	missense	probably benign	0.33
R5689:Dnah7a	UTSW	1	53,444,857 (GRCm39)	missense	possibly damaging	0.87
R5715:Dnah7a	UTSW	1	53,452,937 (GRCm39)	missense	probably damaging	1.00
R5780:Dnah7a	UTSW	1	53,522,478 (GRCm39)	missense	probably benign	0.03
R5893:Dnah7a	UTSW	1	53,496,944 (GRCm39)	missense	possibly damaging	0.66
R5946:Dnah7a	UTSW	1	53,598,467 (GRCm39)	missense	probably damaging	1.00
R5995:Dnah7a	UTSW	1	53,659,829 (GRCm39)	missense	probably benign	0.00
R6102:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R6108:Dnah7a	UTSW	1	53,496,004 (GRCm39)	missense	probably damaging	1.00
R6133:Dnah7a	UTSW	1	53,458,814 (GRCm39)	missense	probably benign	0.05
R6168:Dnah7a	UTSW	1	53,450,727 (GRCm39)	missense	probably damaging	1.00
R6175:Dnah7a	UTSW	1	53,472,181 (GRCm39)	missense	probably damaging	1.00
R6211:Dnah7a	UTSW	1	53,458,795 (GRCm39)	missense	probably damaging	0.99
R6282:Dnah7a	UTSW	1	53,542,760 (GRCm39)	missense	probably damaging	1.00
R6329:Dnah7a	UTSW	1	53,580,273 (GRCm39)	missense	probably damaging	1.00
R6344:Dnah7a	UTSW	1	53,436,349 (GRCm39)	missense	probably benign	0.02
R6530:Dnah7a	UTSW	1	53,542,856 (GRCm39)	missense	probably benign	0.04
R6574:Dnah7a	UTSW	1	53,495,693 (GRCm39)	critical splice donor site	probably null
R6608:Dnah7a	UTSW	1	53,564,277 (GRCm39)	missense	probably benign
R6625:Dnah7a	UTSW	1	53,604,916 (GRCm39)	missense	probably benign	0.05
R6661:Dnah7a	UTSW	1	53,662,609 (GRCm39)	missense	probably benign	0.00
R6681:Dnah7a	UTSW	1	53,560,385 (GRCm39)	critical splice acceptor site	probably null
R6747:Dnah7a	UTSW	1	53,675,221 (GRCm39)	missense	probably benign	0.01
R6774:Dnah7a	UTSW	1	53,737,810 (GRCm39)	missense	probably benign
R6823:Dnah7a	UTSW	1	53,495,863 (GRCm39)	missense	probably benign
R6900:Dnah7a	UTSW	1	53,701,510 (GRCm39)	missense	probably damaging	0.97
R6940:Dnah7a	UTSW	1	53,670,836 (GRCm39)	missense	probably benign	0.09
R6956:Dnah7a	UTSW	1	53,616,446 (GRCm39)	missense	probably benign	0.02
R6978:Dnah7a	UTSW	1	53,701,526 (GRCm39)	missense	probably null
R6988:Dnah7a	UTSW	1	53,621,784 (GRCm39)	missense	possibly damaging	0.62
R7026:Dnah7a	UTSW	1	53,543,448 (GRCm39)	missense	probably benign
R7027:Dnah7a	UTSW	1	53,670,665 (GRCm39)	missense	probably benign	0.01
R7033:Dnah7a	UTSW	1	53,518,820 (GRCm39)	missense	probably damaging	1.00
R7072:Dnah7a	UTSW	1	53,458,912 (GRCm39)	missense	probably benign	0.00
R7096:Dnah7a	UTSW	1	53,522,599 (GRCm39)	missense	possibly damaging	0.90
R7142:Dnah7a	UTSW	1	53,452,927 (GRCm39)	nonsense	probably null
R7144:Dnah7a	UTSW	1	53,737,867 (GRCm39)	splice site	probably null
R7167:Dnah7a	UTSW	1	53,542,935 (GRCm39)	missense	probably benign	0.00
R7182:Dnah7a	UTSW	1	53,659,620 (GRCm39)	splice site	probably null
R7196:Dnah7a	UTSW	1	53,724,000 (GRCm39)	missense	probably benign	0.00
R7206:Dnah7a	UTSW	1	53,737,792 (GRCm39)	nonsense	probably null
R7215:Dnah7a	UTSW	1	53,657,509 (GRCm39)	missense	probably damaging	0.99
R7224:Dnah7a	UTSW	1	53,436,420 (GRCm39)	missense	probably benign	0.00
R7264:Dnah7a	UTSW	1	53,557,973 (GRCm39)	missense	probably benign
R7282:Dnah7a	UTSW	1	53,724,059 (GRCm39)	critical splice acceptor site	probably null
R7365:Dnah7a	UTSW	1	53,536,297 (GRCm39)	missense	probably benign
R7392:Dnah7a	UTSW	1	53,540,820 (GRCm39)	missense	probably benign	0.00
R7454:Dnah7a	UTSW	1	53,557,923 (GRCm39)	missense	probably benign
R7471:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
R7547:Dnah7a	UTSW	1	53,702,996 (GRCm39)	missense	probably benign	0.00
R7554:Dnah7a	UTSW	1	53,567,857 (GRCm39)	missense	possibly damaging	0.87
R7655:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7656:Dnah7a	UTSW	1	53,535,164 (GRCm39)	missense	possibly damaging	0.50
R7666:Dnah7a	UTSW	1	53,586,456 (GRCm39)	missense	probably benign	0.00
R7721:Dnah7a	UTSW	1	53,670,842 (GRCm39)	missense	probably benign
R7813:Dnah7a	UTSW	1	53,657,245 (GRCm39)	missense	probably benign
R7839:Dnah7a	UTSW	1	53,606,334 (GRCm39)	missense	probably benign	0.08
R7959:Dnah7a	UTSW	1	53,682,621 (GRCm39)	missense	probably benign	0.00
R7984:Dnah7a	UTSW	1	53,543,377 (GRCm39)	missense	probably benign	0.01
R7985:Dnah7a	UTSW	1	53,557,886 (GRCm39)	missense	probably damaging	1.00
R8116:Dnah7a	UTSW	1	53,543,049 (GRCm39)	missense	probably benign
R8140:Dnah7a	UTSW	1	53,540,748 (GRCm39)	missense	probably benign	0.02
R8184:Dnah7a	UTSW	1	53,666,194 (GRCm39)	missense	probably benign	0.03
R8339:Dnah7a	UTSW	1	53,724,178 (GRCm39)	missense	probably benign
R8352:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8423:Dnah7a	UTSW	1	53,512,063 (GRCm39)	missense	possibly damaging	0.84
R8428:Dnah7a	UTSW	1	53,512,112 (GRCm39)	missense	probably damaging	0.98
R8432:Dnah7a	UTSW	1	53,657,195 (GRCm39)	missense	possibly damaging	0.46
R8452:Dnah7a	UTSW	1	53,466,986 (GRCm39)	missense	probably null	0.01
R8458:Dnah7a	UTSW	1	53,657,142 (GRCm39)	missense	probably benign	0.01
R8493:Dnah7a	UTSW	1	53,512,067 (GRCm39)	missense	probably damaging	1.00
R8498:Dnah7a	UTSW	1	53,657,139 (GRCm39)	missense	probably benign	0.01
R8502:Dnah7a	UTSW	1	53,679,520 (GRCm39)	missense	probably benign	0.39
R8700:Dnah7a	UTSW	1	53,535,088 (GRCm39)	missense	possibly damaging	0.62
R8709:Dnah7a	UTSW	1	53,674,476 (GRCm39)	missense	probably benign
R8856:Dnah7a	UTSW	1	53,462,422 (GRCm39)	missense	probably damaging	1.00
R8875:Dnah7a	UTSW	1	53,682,682 (GRCm39)	missense	probably benign	0.10
R8967:Dnah7a	UTSW	1	53,682,594 (GRCm39)	splice site	probably benign
R8982:Dnah7a	UTSW	1	53,570,301 (GRCm39)	missense	probably benign
R8984:Dnah7a	UTSW	1	53,674,436 (GRCm39)	nonsense	probably null
R8993:Dnah7a	UTSW	1	53,543,262 (GRCm39)	missense	probably damaging	1.00
R9008:Dnah7a	UTSW	1	53,701,501 (GRCm39)	missense	possibly damaging	0.81
R9022:Dnah7a	UTSW	1	53,512,116 (GRCm39)	critical splice acceptor site	probably null
R9028:Dnah7a	UTSW	1	53,560,297 (GRCm39)	missense	probably benign	0.00
R9077:Dnah7a	UTSW	1	53,741,218 (GRCm39)	missense	unknown
R9167:Dnah7a	UTSW	1	53,657,370 (GRCm39)	missense	probably benign	0.00
R9206:Dnah7a	UTSW	1	53,540,757 (GRCm39)	missense	probably benign	0.11
R9226:Dnah7a	UTSW	1	53,560,326 (GRCm39)	missense	possibly damaging	0.93
R9251:Dnah7a	UTSW	1	53,621,671 (GRCm39)	missense	probably damaging	1.00
R9265:Dnah7a	UTSW	1	53,674,505 (GRCm39)	missense	probably benign
R9350:Dnah7a	UTSW	1	53,436,307 (GRCm39)	missense	probably benign	0.19
R9369:Dnah7a	UTSW	1	53,564,222 (GRCm39)	missense	possibly damaging	0.72
R9369:Dnah7a	UTSW	1	53,543,421 (GRCm39)	missense	probably benign
R9372:Dnah7a	UTSW	1	53,543,474 (GRCm39)	missense	probably benign
R9376:Dnah7a	UTSW	1	53,568,058 (GRCm39)	critical splice acceptor site	probably null
R9378:Dnah7a	UTSW	1	53,621,776 (GRCm39)	missense	probably benign	0.32
R9401:Dnah7a	UTSW	1	53,568,026 (GRCm39)	missense	probably benign	0.01
R9431:Dnah7a	UTSW	1	53,450,812 (GRCm39)	missense	possibly damaging	0.90
R9529:Dnah7a	UTSW	1	53,561,495 (GRCm39)	missense	probably damaging	1.00
R9701:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
R9712:Dnah7a	UTSW	1	53,598,299 (GRCm39)	missense	probably benign	0.00
R9799:Dnah7a	UTSW	1	53,557,968 (GRCm39)	missense	probably benign	0.00
R9802:Dnah7a	UTSW	1	53,561,388 (GRCm39)	missense	probably benign	0.03
X0027:Dnah7a	UTSW	1	53,512,089 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnah7a	UTSW	1	53,507,802 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,522,622 (GRCm39)	missense	probably damaging	1.00
Z1176:Dnah7a	UTSW	1	53,458,858 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah7a	UTSW	1	53,598,261 (GRCm39)	missense	probably benign	0.21
Z1177:Dnah7a	UTSW	1	53,450,815 (GRCm39)	missense	probably benign	0.08
Z1177:Dnah7a	UTSW	1	53,682,616 (GRCm39)	missense	possibly damaging	0.92

Predicted Primers

PCR Primer
(F):5'- GAATTGCTTTACAGGGCTGG -3'
(R):5'- AGCAAGGAATGTTGGGCTTC -3'

Sequencing Primer
(F):5'- CTTTACAGGGCTGGGGTGACAG -3'
(R):5'- GGCTTCTGCTTAAGTTGCAAC -3'

Posted On

2021-04-30