Incidental Mutation 'R8698:Adgre1'
| ID |
668885 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgre1
|
| Ensembl Gene |
ENSMUSG00000004730 |
| Gene Name |
adhesion G protein-coupled receptor E1 |
| Synonyms |
DD7A5-7, EGF-TM7, Emr1, Ly71, F4/80, TM7LN3 |
| MMRRC Submission |
068552-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.190)
|
| Stock # |
R8698 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
57665691-57790527 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 57709003 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 65
(S65P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000004850
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000004850]
[ENSMUST00000086763]
|
| AlphaFold |
Q61549 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000004850
AA Change: S65P
PolyPhen 2
Score 0.054 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000004850
Gene: ENSMUSG00000004730
AA Change: S65P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
EGF
|
35 |
80 |
1.43e-1 |
SMART |
|
EGF_CA
|
81 |
122 |
3.59e-7 |
SMART |
|
EGF_CA
|
133 |
172 |
4.56e-9 |
SMART |
|
EGF_CA
|
173 |
221 |
1.29e-8 |
SMART |
|
EGF_CA
|
222 |
271 |
2.31e-10 |
SMART |
|
EGF_CA
|
272 |
318 |
1.06e-9 |
SMART |
|
EGF_CA
|
319 |
367 |
1.18e-7 |
SMART |
|
GPS
|
591 |
641 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
644 |
885 |
2.1e-63 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000086763
AA Change: S65P
PolyPhen 2
Score 0.054 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000083971
Gene: ENSMUSG00000004730
AA Change: S65P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
EGF
|
35 |
80 |
1.43e-1 |
SMART |
|
EGF_CA
|
81 |
122 |
3.59e-7 |
SMART |
|
EGF_CA
|
133 |
172 |
4.56e-9 |
SMART |
|
EGF_CA
|
173 |
221 |
1.29e-8 |
SMART |
|
EGF_CA
|
222 |
271 |
2.31e-10 |
SMART |
|
EGF_CA
|
272 |
318 |
1.06e-9 |
SMART |
|
EGF_CA
|
319 |
367 |
1.18e-7 |
SMART |
|
GPS
|
591 |
641 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
644 |
885 |
2.1e-63 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
PHENOTYPE: Homozygous null mice fail to develop peripheral tolerance after inoculation with antigen because of a lack of efferent regulatory T cell development. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Chemically induced(1)
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aaas |
A |
G |
15: 102,247,250 (GRCm39) |
|
probably benign |
Het |
| Adamtsl1 |
A |
G |
4: 86,306,714 (GRCm39) |
N1384S |
probably benign |
Het |
| Adgrl4 |
G |
T |
3: 151,203,512 (GRCm39) |
C124F |
probably damaging |
Het |
| Aldh1b1 |
G |
A |
4: 45,802,942 (GRCm39) |
G160D |
probably damaging |
Het |
| Alpi |
T |
G |
1: 87,028,208 (GRCm39) |
D205A |
probably damaging |
Het |
| AW146154 |
C |
A |
7: 41,129,934 (GRCm39) |
R394L |
probably benign |
Het |
| Bcl10 |
G |
A |
3: 145,639,022 (GRCm39) |
M221I |
probably benign |
Het |
| Brpf3 |
G |
A |
17: 29,037,436 (GRCm39) |
R768H |
probably damaging |
Het |
| Cad |
G |
T |
5: 31,234,819 (GRCm39) |
R2116L |
probably benign |
Het |
| Cand2 |
G |
T |
6: 115,763,852 (GRCm39) |
R258L |
probably damaging |
Het |
| Car4 |
A |
T |
11: 84,855,009 (GRCm39) |
N119I |
probably benign |
Het |
| Carmil1 |
C |
T |
13: 24,220,229 (GRCm39) |
G1165D |
probably damaging |
Het |
| Ccdc66 |
T |
C |
14: 27,212,647 (GRCm39) |
T403A |
probably benign |
Het |
| Cdon |
T |
G |
9: 35,398,269 (GRCm39) |
|
probably null |
Het |
| Cemip |
T |
C |
7: 83,607,790 (GRCm39) |
I739V |
probably damaging |
Het |
| Cep85l |
A |
G |
10: 53,234,201 (GRCm39) |
I59T |
probably damaging |
Het |
| Clec4f |
A |
T |
6: 83,630,267 (GRCm39) |
V97D |
probably benign |
Het |
| Cnot6l |
A |
G |
5: 96,225,149 (GRCm39) |
C515R |
probably damaging |
Het |
| Cntnap2 |
G |
A |
6: 47,026,156 (GRCm39) |
G935D |
probably damaging |
Het |
| Cntrl |
A |
G |
2: 35,023,974 (GRCm39) |
H553R |
probably damaging |
Het |
| Cops3 |
A |
G |
11: 59,708,886 (GRCm39) |
S423P |
probably damaging |
Het |
| Cox15 |
C |
T |
19: 43,739,948 (GRCm39) |
R39H |
probably benign |
Het |
| Ctnna2 |
A |
G |
6: 77,630,100 (GRCm39) |
V131A |
probably benign |
Het |
| Dcst2 |
T |
A |
3: 89,276,044 (GRCm39) |
F392I |
probably benign |
Het |
| Decr1 |
A |
G |
4: 15,922,483 (GRCm39) |
|
probably null |
Het |
| Dennd3 |
A |
C |
15: 73,394,154 (GRCm39) |
T60P |
possibly damaging |
Het |
| Dipk1a |
A |
T |
5: 108,057,776 (GRCm39) |
F261I |
probably damaging |
Het |
| Dmxl2 |
T |
C |
9: 54,281,953 (GRCm39) |
N2859S |
probably benign |
Het |
| Dnah12 |
A |
T |
14: 26,428,418 (GRCm39) |
I280F |
probably benign |
Het |
| Dnah8 |
A |
C |
17: 31,094,009 (GRCm39) |
D4701A |
probably damaging |
Het |
| Dyrk1a |
C |
A |
16: 94,487,414 (GRCm39) |
H541Q |
possibly damaging |
Het |
| Eml4 |
T |
C |
17: 83,785,345 (GRCm39) |
S906P |
probably benign |
Het |
| Fam169a |
G |
T |
13: 97,243,578 (GRCm39) |
V203F |
probably damaging |
Het |
| Fmn1 |
C |
T |
2: 113,260,152 (GRCm39) |
L682F |
unknown |
Het |
| Gli2 |
T |
C |
1: 118,769,887 (GRCm39) |
Y555C |
probably damaging |
Het |
| Gm3278 |
A |
G |
14: 16,081,505 (GRCm39) |
Y130C |
possibly damaging |
Het |
| Gm8237 |
T |
A |
14: 5,863,554 (GRCm38) |
Y37F |
probably damaging |
Het |
| Golga4 |
T |
G |
9: 118,385,029 (GRCm39) |
L717R |
probably damaging |
Het |
| Gtpbp4 |
C |
T |
13: 9,024,249 (GRCm39) |
R568H |
probably benign |
Het |
| Il1f10 |
A |
G |
2: 24,183,197 (GRCm39) |
N47S |
probably damaging |
Het |
| Itga6 |
A |
G |
2: 71,673,618 (GRCm39) |
H884R |
probably benign |
Het |
| Kdm1a |
T |
C |
4: 136,286,518 (GRCm39) |
K482R |
probably benign |
Het |
| Klk12 |
T |
C |
7: 43,419,113 (GRCm39) |
V26A |
probably benign |
Het |
| Lrp2 |
T |
A |
2: 69,278,583 (GRCm39) |
R3923S |
probably benign |
Het |
| Lrp2 |
C |
T |
2: 69,288,767 (GRCm39) |
V3700M |
probably benign |
Het |
| Lrrk2 |
A |
G |
15: 91,636,400 (GRCm39) |
D1458G |
probably benign |
Het |
| Mapre2 |
T |
A |
18: 24,011,090 (GRCm39) |
S233T |
probably benign |
Het |
| Mki67 |
T |
C |
7: 135,296,937 (GRCm39) |
D2699G |
possibly damaging |
Het |
| Mthfr |
T |
A |
4: 148,128,947 (GRCm39) |
Y214* |
probably null |
Het |
| Ncoa6 |
A |
T |
2: 155,257,041 (GRCm39) |
M834K |
possibly damaging |
Het |
| Neurl2 |
C |
T |
2: 164,675,054 (GRCm39) |
D103N |
probably benign |
Het |
| Niban3 |
T |
A |
8: 72,060,159 (GRCm39) |
I93N |
unknown |
Het |
| Or1j15 |
T |
C |
2: 36,458,915 (GRCm39) |
Y102H |
possibly damaging |
Het |
| Or2ag16 |
A |
T |
7: 106,352,571 (GRCm39) |
V8E |
probably benign |
Het |
| Or2b7 |
G |
A |
13: 21,739,890 (GRCm39) |
L101F |
probably damaging |
Het |
| P2ry14 |
A |
G |
3: 59,022,596 (GRCm39) |
V288A |
possibly damaging |
Het |
| Pde6b |
G |
T |
5: 108,576,105 (GRCm39) |
S730I |
possibly damaging |
Het |
| Pdpk1 |
A |
T |
17: 24,298,542 (GRCm39) |
V496D |
probably damaging |
Het |
| Plekho2 |
A |
T |
9: 65,463,554 (GRCm39) |
L432M |
probably damaging |
Het |
| Ppa2 |
T |
C |
3: 133,082,362 (GRCm39) |
L151P |
unknown |
Het |
| Ppp2r3c |
G |
A |
12: 55,328,499 (GRCm39) |
T422I |
probably benign |
Het |
| Prelid3a |
T |
C |
18: 67,610,122 (GRCm39) |
S151P |
probably damaging |
Het |
| Rad21l |
G |
A |
2: 151,487,373 (GRCm39) |
P537L |
probably damaging |
Het |
| Sacs |
T |
A |
14: 61,450,802 (GRCm39) |
S4283T |
probably benign |
Het |
| Samd9l |
A |
T |
6: 3,373,843 (GRCm39) |
D1139E |
probably benign |
Het |
| Scn9a |
G |
T |
2: 66,366,628 (GRCm39) |
H718Q |
probably benign |
Het |
| Slc1a3 |
A |
T |
15: 8,668,636 (GRCm39) |
I443N |
probably damaging |
Het |
| Slc22a6 |
A |
G |
19: 8,600,889 (GRCm39) |
M361V |
probably benign |
Het |
| Slc8a2 |
A |
G |
7: 15,891,132 (GRCm39) |
Y724C |
probably damaging |
Het |
| Slf1 |
A |
T |
13: 77,197,284 (GRCm39) |
S777T |
possibly damaging |
Het |
| Sltm |
T |
C |
9: 70,494,352 (GRCm39) |
S901P |
probably benign |
Het |
| Smc1b |
A |
T |
15: 84,997,047 (GRCm39) |
H524Q |
probably benign |
Het |
| Spast |
T |
C |
17: 74,666,341 (GRCm39) |
S225P |
probably benign |
Het |
| Srsf12 |
C |
T |
4: 33,231,246 (GRCm39) |
R252W |
probably damaging |
Het |
| Syne1 |
A |
G |
10: 5,179,229 (GRCm39) |
L4415P |
probably damaging |
Het |
| Tmem117 |
A |
T |
15: 94,535,990 (GRCm39) |
Y8F |
probably benign |
Het |
| Tmem241 |
T |
C |
18: 12,197,288 (GRCm39) |
D180G |
possibly damaging |
Het |
| Tomm40 |
C |
T |
7: 19,444,890 (GRCm39) |
V164I |
probably benign |
Het |
| Ttc41 |
T |
C |
10: 86,548,841 (GRCm39) |
Y12H |
probably benign |
Het |
| Twnk |
T |
C |
19: 44,996,299 (GRCm39) |
V244A |
probably benign |
Het |
| Ugt1a8 |
T |
C |
1: 88,015,952 (GRCm39) |
S122P |
probably damaging |
Het |
| Vmn1r78 |
A |
G |
7: 11,886,539 (GRCm39) |
K50R |
probably benign |
Het |
| Vmn2r10 |
A |
G |
5: 109,151,390 (GRCm39) |
F75L |
probably benign |
Het |
| Wbp4 |
G |
T |
14: 79,707,573 (GRCm39) |
Y179* |
probably null |
Het |
| Zfp106 |
A |
G |
2: 120,354,600 (GRCm39) |
|
probably null |
Het |
| Zfp974 |
A |
T |
7: 27,610,361 (GRCm39) |
C455S |
possibly damaging |
Het |
|
| Other mutations in Adgre1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Adgre1
|
APN |
17 |
57,757,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00966:Adgre1
|
APN |
17 |
57,726,335 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01680:Adgre1
|
APN |
17 |
57,709,620 (GRCm39) |
missense |
unknown |
|
|
IGL01724:Adgre1
|
APN |
17 |
57,751,064 (GRCm39) |
nonsense |
probably null |
|
|
IGL02172:Adgre1
|
APN |
17 |
57,785,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02260:Adgre1
|
APN |
17 |
57,754,891 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02272:Adgre1
|
APN |
17 |
57,757,021 (GRCm39) |
nonsense |
probably null |
|
|
IGL02336:Adgre1
|
APN |
17 |
57,718,024 (GRCm39) |
nonsense |
probably null |
|
|
IGL02346:Adgre1
|
APN |
17 |
57,750,919 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02398:Adgre1
|
APN |
17 |
57,709,824 (GRCm39) |
nonsense |
probably null |
|
|
IGL02618:Adgre1
|
APN |
17 |
57,751,021 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02690:Adgre1
|
APN |
17 |
57,787,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02936:Adgre1
|
APN |
17 |
57,785,833 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL03112:Adgre1
|
APN |
17 |
57,755,029 (GRCm39) |
splice site |
probably null |
|
|
IGL03350:Adgre1
|
APN |
17 |
57,708,908 (GRCm39) |
missense |
probably benign |
0.16 |
|
F480
|
UTSW |
17 |
57,751,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
lomax
|
UTSW |
17 |
57,709,811 (GRCm39) |
missense |
unknown |
|
|
Onion
|
UTSW |
17 |
57,709,841 (GRCm39) |
nonsense |
probably null |
|
|
Scallion
|
UTSW |
17 |
57,708,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0049:Adgre1
|
UTSW |
17 |
57,709,841 (GRCm39) |
nonsense |
probably null |
|
|
R0153:Adgre1
|
UTSW |
17 |
57,750,939 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0277:Adgre1
|
UTSW |
17 |
57,751,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0278:Adgre1
|
UTSW |
17 |
57,754,872 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0323:Adgre1
|
UTSW |
17 |
57,751,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0389:Adgre1
|
UTSW |
17 |
57,713,839 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0492:Adgre1
|
UTSW |
17 |
57,709,742 (GRCm39) |
missense |
unknown |
|
|
R0621:Adgre1
|
UTSW |
17 |
57,748,359 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0647:Adgre1
|
UTSW |
17 |
57,718,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1310:Adgre1
|
UTSW |
17 |
57,754,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1601:Adgre1
|
UTSW |
17 |
57,748,353 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1689:Adgre1
|
UTSW |
17 |
57,756,921 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1708:Adgre1
|
UTSW |
17 |
57,708,974 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1796:Adgre1
|
UTSW |
17 |
57,748,350 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1839:Adgre1
|
UTSW |
17 |
57,748,299 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1860:Adgre1
|
UTSW |
17 |
57,748,363 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2165:Adgre1
|
UTSW |
17 |
57,726,338 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2219:Adgre1
|
UTSW |
17 |
57,708,912 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2519:Adgre1
|
UTSW |
17 |
57,717,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Adgre1
|
UTSW |
17 |
57,708,925 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3911:Adgre1
|
UTSW |
17 |
57,754,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4190:Adgre1
|
UTSW |
17 |
57,709,811 (GRCm39) |
missense |
unknown |
|
|
R4439:Adgre1
|
UTSW |
17 |
57,754,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4513:Adgre1
|
UTSW |
17 |
57,717,947 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4529:Adgre1
|
UTSW |
17 |
57,727,519 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4543:Adgre1
|
UTSW |
17 |
57,713,874 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4610:Adgre1
|
UTSW |
17 |
57,757,073 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4665:Adgre1
|
UTSW |
17 |
57,787,947 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4911:Adgre1
|
UTSW |
17 |
57,754,832 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4928:Adgre1
|
UTSW |
17 |
57,751,064 (GRCm39) |
nonsense |
probably null |
|
|
R4942:Adgre1
|
UTSW |
17 |
57,713,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Adgre1
|
UTSW |
17 |
57,750,918 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4953:Adgre1
|
UTSW |
17 |
57,748,321 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5107:Adgre1
|
UTSW |
17 |
57,708,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5366:Adgre1
|
UTSW |
17 |
57,709,817 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5590:Adgre1
|
UTSW |
17 |
57,752,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Adgre1
|
UTSW |
17 |
57,727,437 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5699:Adgre1
|
UTSW |
17 |
57,788,007 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5734:Adgre1
|
UTSW |
17 |
57,750,990 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5860:Adgre1
|
UTSW |
17 |
57,752,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6039:Adgre1
|
UTSW |
17 |
57,713,859 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6039:Adgre1
|
UTSW |
17 |
57,713,859 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6149:Adgre1
|
UTSW |
17 |
57,752,018 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6478:Adgre1
|
UTSW |
17 |
57,708,955 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6709:Adgre1
|
UTSW |
17 |
57,713,917 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6864:Adgre1
|
UTSW |
17 |
57,785,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6945:Adgre1
|
UTSW |
17 |
57,727,399 (GRCm39) |
missense |
probably benign |
0.39 |
|
R6945:Adgre1
|
UTSW |
17 |
57,717,844 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6988:Adgre1
|
UTSW |
17 |
57,715,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7019:Adgre1
|
UTSW |
17 |
57,717,945 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7154:Adgre1
|
UTSW |
17 |
57,751,087 (GRCm39) |
splice site |
probably null |
|
|
R7347:Adgre1
|
UTSW |
17 |
57,727,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7459:Adgre1
|
UTSW |
17 |
57,756,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7709:Adgre1
|
UTSW |
17 |
57,709,519 (GRCm39) |
missense |
unknown |
|
|
R7939:Adgre1
|
UTSW |
17 |
57,756,938 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7977:Adgre1
|
UTSW |
17 |
57,754,987 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7987:Adgre1
|
UTSW |
17 |
57,754,987 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8187:Adgre1
|
UTSW |
17 |
57,727,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8210:Adgre1
|
UTSW |
17 |
57,752,061 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8223:Adgre1
|
UTSW |
17 |
57,668,692 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8344:Adgre1
|
UTSW |
17 |
57,715,459 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9236:Adgre1
|
UTSW |
17 |
57,709,782 (GRCm39) |
nonsense |
probably null |
|
|
R9262:Adgre1
|
UTSW |
17 |
57,754,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9303:Adgre1
|
UTSW |
17 |
57,748,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9305:Adgre1
|
UTSW |
17 |
57,748,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:Adgre1
|
UTSW |
17 |
57,718,083 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9661:Adgre1
|
UTSW |
17 |
57,748,368 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9678:Adgre1
|
UTSW |
17 |
57,750,997 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9751:Adgre1
|
UTSW |
17 |
57,757,101 (GRCm39) |
missense |
probably null |
0.06 |
|
R9785:Adgre1
|
UTSW |
17 |
57,785,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgre1
|
UTSW |
17 |
57,668,729 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1177:Adgre1
|
UTSW |
17 |
57,726,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCATAGGCAGGAGACTCTAGGG -3'
(R):5'- TCAGATTCACAAGGTTCCTTCC -3'
Sequencing Primer
(F):5'- AGACTCTAGGGTGTGACTCCTC -3'
(R):5'- AAGGTTCCTTCCCTTGGACATATG -3'
|
| Posted On |
2021-04-30 |
Incidental Mutation