Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01335:Naa16'

74616

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Naa16

Ensembl Gene

ENSMUSG00000022020

Gene Name

N(alpha)-acetyltransferase 16, NatA auxiliary subunit

Synonyms

Narg1l, 1300019C06Rik

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.066) question?

Stock #

IGL01335

Quality Score

Status

Chromosome

Chromosomal Location

79325269-79390778 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 79345116 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000131268 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022597] [ENSMUST00000163486]

AlphaFold

Q9DBB4

Predicted Effect

probably benign
Transcript: ENSMUST00000022597

SMART Domains

Protein: ENSMUSP00000022597
Gene: ENSMUSG00000022020

Domain	Start	End	E-Value	Type
TPR	46	79	2.99e1	SMART
TPR	80	113	2.98e-3	SMART
Blast:TPR	224	257	1e-10	BLAST
TPR	374	407	9.96e0	SMART
TPR	408	441	7.47e0	SMART
low complexity region	616	633	N/A	INTRINSIC
Blast:TPR	672	705	3e-12	BLAST
low complexity region	830	841	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000163486

SMART Domains

Protein: ENSMUSP00000131268
Gene: ENSMUSG00000022020

Domain	Start	End	E-Value	Type
TPR	12	45	2.99e1	SMART
TPR	46	79	2.98e-3	SMART
Blast:TPR	190	223	3e-10	BLAST
TPR	340	373	9.96e0	SMART
TPR	374	407	7.47e0	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000171928

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000227775

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700029J07Rik	A	T	8: 45,973,605		probably benign	Het
6820408C15Rik	T	A	2: 152,442,387	M300K	possibly damaging	Het
Adamts14	T	A	10: 61,198,681	R1143W	possibly damaging	Het
Ankrd28	T	C	14: 31,702,024	Y1083C	probably damaging	Het
Anxa8	T	C	14: 34,089,590	M34T	probably damaging	Het
Aox1	G	T	1: 58,082,153	E928*	probably null	Het
Atp8b5	T	A	4: 43,302,628	F50L	possibly damaging	Het
Brpf1	A	G	6: 113,319,337	S863G	probably damaging	Het
Cdc42bpb	A	G	12: 111,294,096		probably benign	Het
Cdh6	C	T	15: 13,051,309	A413T	probably benign	Het
Cfap97	A	G	8: 46,170,455	Q294R	probably damaging	Het
Cit	C	T	5: 115,908,830		probably benign	Het
Dmbt1	A	G	7: 131,088,767	Y736C	possibly damaging	Het
Eno2	C	T	6: 124,766,655	G107E	probably damaging	Het
Gja8	T	C	3: 96,919,242	Q368R	probably benign	Het
Gm3633	T	A	14: 42,640,638		probably benign	Het
Gm4987	A	T	X: 46,455,878		noncoding transcript	Het
Gna13	G	A	11: 109,365,743	R164Q	probably damaging	Het
Grhl1	A	T	12: 24,608,058	E351D	probably damaging	Het
Idua	A	G	5: 108,680,871	Q280R	probably benign	Het
Igsf5	T	A	16: 96,373,153		probably benign	Het
Mrpl52	T	C	14: 54,427,199	Y39H	probably damaging	Het
Naa35	T	A	13: 59,616,796	L338Q	probably damaging	Het
Nat8l	A	T	5: 33,998,447	Y149F	probably benign	Het
Nck1	A	T	9: 100,497,737	W154R	probably damaging	Het
Ncoa1	A	T	12: 4,297,520	S351R	probably benign	Het
Olfr1046	A	T	2: 86,217,572	L46Q	probably damaging	Het
Olfr1145	A	T	2: 87,810,446	T209S	probably damaging	Het
Olfr1490	A	T	19: 13,655,176	H249L	probably damaging	Het
Olfr765	T	C	10: 129,046,511	K184R	probably benign	Het
Pacs1	A	T	19: 5,142,632	V624E	probably damaging	Het
Pde6b	G	A	5: 108,423,513	R444H	probably benign	Het
Pigk	A	T	3: 152,742,536	T226S	probably benign	Het
Prkdc	T	C	16: 15,816,896		probably null	Het
Ptbp1	G	A	10: 79,862,874		probably null	Het
Pyroxd1	T	C	6: 142,361,758	V418A	probably damaging	Het
Rhot1	A	T	11: 80,250,229	D421V	probably damaging	Het
Rimkla	T	C	4: 119,477,959	T76A	possibly damaging	Het
Rtn1	A	G	12: 72,308,350	V274A	probably benign	Het
Tatdn2	T	A	6: 113,704,056	M289K	probably benign	Het
Trak1	A	G	9: 121,454,316	T476A	possibly damaging	Het
Ube2i	C	A	17: 25,269,436	Q11H	probably damaging	Het
Ugt2a3	A	T	5: 87,336,785	C127S	probably damaging	Het
Uimc1	T	A	13: 55,034,911	Q619L	probably benign	Het
Upk3a	T	A	15: 85,019,585	Y162N	probably damaging	Het
Usp33	T	C	3: 152,392,217	S849P	probably damaging	Het
Vmn2r120	G	A	17: 57,525,732	T149I	possibly damaging	Het
Vmn2r15	G	A	5: 109,286,736	P701S	possibly damaging	Het
Vmn2r28	T	C	7: 5,481,088	I704M	possibly damaging	Het
Wdhd1	T	C	14: 47,250,782	E756G	possibly damaging	Het
Xlr3c	C	A	X: 73,260,033	V102F	probably benign	Het
Zfp384	T	G	6: 125,025,053	D220E	probably benign	Het
Zfp521	A	T	18: 13,844,719	V879E	probably benign	Het

Other mutations in Naa16

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00551:Naa16	APN	14	79355729	missense	probably damaging	1.00
IGL01025:Naa16	APN	14	79384756	missense	probably damaging	1.00
IGL01155:Naa16	APN	14	79384715	missense	probably damaging	0.98
IGL01981:Naa16	APN	14	79381516	missense	probably benign	0.05
IGL02230:Naa16	APN	14	79377361	splice site	probably benign
IGL02313:Naa16	APN	14	79384668	missense	probably damaging	1.00
IGL02418:Naa16	APN	14	79383366	missense	probably damaging	1.00
IGL02544:Naa16	APN	14	79335820	missense	probably damaging	1.00
IGL03051:Naa16	APN	14	79369082	missense	probably benign	0.01
IGL03064:Naa16	APN	14	79339628	missense	probably damaging	0.98
IGL03205:Naa16	APN	14	79356512	missense	possibly damaging	0.89
PIT4508001:Naa16	UTSW	14	79369087	missense	probably benign	0.15
R0651:Naa16	UTSW	14	79351392	missense	probably damaging	1.00
R1429:Naa16	UTSW	14	79359527	missense	probably benign	0.01
R1674:Naa16	UTSW	14	79387057	start codon destroyed	probably null	0.65
R1693:Naa16	UTSW	14	79351456	missense	probably damaging	1.00
R1874:Naa16	UTSW	14	79355743	missense	possibly damaging	0.62
R1992:Naa16	UTSW	14	79356491	missense	probably damaging	1.00
R2015:Naa16	UTSW	14	79345059	missense	probably damaging	1.00
R2391:Naa16	UTSW	14	79370049	missense	probably benign	0.16
R2847:Naa16	UTSW	14	79335883	missense	probably damaging	1.00
R2848:Naa16	UTSW	14	79335883	missense	probably damaging	1.00
R2877:Naa16	UTSW	14	79343298	missense	probably benign	0.00
R3884:Naa16	UTSW	14	79343262	missense	probably damaging	0.98
R4001:Naa16	UTSW	14	79343121	splice site	probably null
R4199:Naa16	UTSW	14	79355871	missense	probably damaging	1.00
R4638:Naa16	UTSW	14	79340033	splice site	probably null
R4676:Naa16	UTSW	14	79336348	unclassified	probably benign
R4690:Naa16	UTSW	14	79345057	missense	probably damaging	1.00
R4952:Naa16	UTSW	14	79345085	missense	probably damaging	1.00
R5087:Naa16	UTSW	14	79377415	missense	possibly damaging	0.68
R5104:Naa16	UTSW	14	79384700	nonsense	probably null
R5729:Naa16	UTSW	14	79355780	missense	probably damaging	1.00
R6178:Naa16	UTSW	14	79383340	missense	possibly damaging	0.93
R6960:Naa16	UTSW	14	79359471	missense	possibly damaging	0.65
R7794:Naa16	UTSW	14	79377494	missense	probably damaging	1.00
R7936:Naa16	UTSW	14	79341046	missense	possibly damaging	0.47
R8356:Naa16	UTSW	14	79359475	missense	probably benign	0.00
R8456:Naa16	UTSW	14	79359475	missense	probably benign	0.00
R8892:Naa16	UTSW	14	79390576	missense	probably benign	0.32
R8931:Naa16	UTSW	14	79344955	missense	probably damaging	1.00
R9010:Naa16	UTSW	14	79370042	missense	probably benign	0.01
R9068:Naa16	UTSW	14	79374849	missense	probably benign	0.18
R9360:Naa16	UTSW	14	79356503	missense	probably benign	0.05
R9688:Naa16	UTSW	14	79335869	nonsense	probably null
X0064:Naa16	UTSW	14	79351389	missense	probably damaging	1.00
Z1177:Naa16	UTSW	14	79344979	missense	probably damaging	1.00

Posted On

2013-10-07