Incidental Mutation 'IGL01646:Vmn2r99'
| ID |
102691 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn2r99
|
| Ensembl Gene |
ENSMUSG00000090304 |
| Gene Name |
vomeronasal 2, receptor 99 |
| Synonyms |
EG665376 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.131)
|
| Stock # |
IGL01646
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
19361949-19401098 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
C to A
at 19393658 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156067
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000176107]
[ENSMUST00000231989]
|
| AlphaFold |
H3BK37 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176107
|
| SMART Domains |
Protein: ENSMUSP00000135236
Gene: ENSMUSG00000090304
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:ANF_receptor
|
81 |
448 |
5.7e-33 |
PFAM |
|
Pfam:NCD3G
|
508 |
561 |
1.8e-21 |
PFAM |
|
Pfam:7tm_3
|
593 |
829 |
4.6e-52 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231989
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 46 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700011I03Rik |
T |
A |
18: 57,667,345 |
C171* |
probably null |
Het |
| Ambp |
C |
T |
4: 63,148,740 |
V188I |
probably benign |
Het |
| Bbs9 |
G |
T |
9: 22,670,925 |
E638* |
probably null |
Het |
| Bmp6 |
A |
G |
13: 38,498,928 |
M465V |
probably damaging |
Het |
| Cemip |
T |
C |
7: 83,983,232 |
E374G |
possibly damaging |
Het |
| Cnbd1 |
A |
T |
4: 18,895,141 |
Y200* |
probably null |
Het |
| Cox6b1 |
G |
T |
7: 30,624,504 |
Y34* |
probably null |
Het |
| Cyp2d26 |
A |
C |
15: 82,791,418 |
I303M |
probably benign |
Het |
| Diaph1 |
T |
A |
18: 37,893,416 |
|
probably null |
Het |
| Dmp1 |
T |
C |
5: 104,211,865 |
S136P |
probably damaging |
Het |
| Dpy19l1 |
C |
T |
9: 24,485,069 |
R117Q |
probably damaging |
Het |
| Eea1 |
A |
G |
10: 95,997,015 |
T241A |
probably damaging |
Het |
| Erap1 |
C |
A |
13: 74,666,172 |
T25K |
probably damaging |
Het |
| Fras1 |
A |
G |
5: 96,758,148 |
E3137G |
probably benign |
Het |
| Fryl |
C |
T |
5: 73,022,501 |
|
probably null |
Het |
| Gldc |
T |
G |
19: 30,100,765 |
D944A |
possibly damaging |
Het |
| Grm5 |
A |
G |
7: 88,040,059 |
Y546C |
probably damaging |
Het |
| Igkv1-122 |
G |
A |
6: 68,016,744 |
M1I |
probably null |
Het |
| Jag2 |
G |
A |
12: 112,916,349 |
P380S |
possibly damaging |
Het |
| Kcnc2 |
T |
C |
10: 112,272,406 |
|
probably null |
Het |
| Kmt2a |
T |
C |
9: 44,825,484 |
|
probably benign |
Het |
| Lrrc55 |
A |
G |
2: 85,191,989 |
V286A |
probably damaging |
Het |
| Mllt10 |
C |
A |
2: 18,122,317 |
H82N |
probably damaging |
Het |
| Myh11 |
C |
A |
16: 14,221,775 |
R837L |
probably damaging |
Het |
| Nsg1 |
C |
A |
5: 38,155,691 |
D55Y |
probably damaging |
Het |
| Nup107 |
C |
A |
10: 117,781,342 |
R221M |
probably damaging |
Het |
| Nup153 |
G |
T |
13: 46,684,107 |
A1213D |
possibly damaging |
Het |
| Ovgp1 |
G |
A |
3: 105,978,349 |
G174S |
probably damaging |
Het |
| Papss2 |
C |
T |
19: 32,652,082 |
A357V |
probably benign |
Het |
| Pclo |
A |
G |
5: 14,713,867 |
K4118R |
unknown |
Het |
| Pde2a |
T |
C |
7: 101,507,711 |
I628T |
possibly damaging |
Het |
| Pla2r1 |
A |
G |
2: 60,495,364 |
W521R |
probably damaging |
Het |
| Pld1 |
A |
T |
3: 28,099,664 |
Q744L |
probably damaging |
Het |
| Pnpo |
T |
A |
11: 96,938,949 |
E251V |
possibly damaging |
Het |
| Rdh10 |
C |
T |
1: 16,108,022 |
H173Y |
possibly damaging |
Het |
| Sgpp2 |
A |
T |
1: 78,416,896 |
I179F |
probably damaging |
Het |
| Slc11a1 |
C |
T |
1: 74,384,740 |
P409L |
probably damaging |
Het |
| Slc35b4 |
T |
A |
6: 34,158,429 |
N316I |
probably benign |
Het |
| Snrnp200 |
A |
G |
2: 127,222,228 |
I712V |
probably benign |
Het |
| Spr |
T |
C |
6: 85,134,240 |
D216G |
possibly damaging |
Het |
| Sri |
G |
A |
5: 8,063,755 |
|
probably null |
Het |
| Tas2r124 |
T |
C |
6: 132,755,369 |
S214P |
probably damaging |
Het |
| Tg |
T |
A |
15: 66,678,087 |
S233T |
probably damaging |
Het |
| Tgfbr3 |
A |
T |
5: 107,121,413 |
|
probably benign |
Het |
| Vmn2r45 |
A |
G |
7: 8,483,338 |
F317S |
probably benign |
Het |
| Zfp957 |
T |
C |
14: 79,213,891 |
E156G |
probably benign |
Het |
|
| Other mutations in Vmn2r99 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00503:Vmn2r99
|
APN |
17 |
19,378,854 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01113:Vmn2r99
|
APN |
17 |
19,394,256 (GRCm38) |
missense |
probably benign |
0.20 |
|
IGL01138:Vmn2r99
|
APN |
17 |
19,382,623 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL01769:Vmn2r99
|
APN |
17 |
19,380,115 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02112:Vmn2r99
|
APN |
17 |
19,380,232 (GRCm38) |
missense |
probably null |
0.99 |
|
IGL02891:Vmn2r99
|
APN |
17 |
19,378,690 (GRCm38) |
nonsense |
probably null |
|
|
IGL03132:Vmn2r99
|
APN |
17 |
19,378,223 (GRCm38) |
nonsense |
probably null |
|
|
FR4548:Vmn2r99
|
UTSW |
17 |
19,394,285 (GRCm38) |
missense |
probably damaging |
0.97 |
|
FR4976:Vmn2r99
|
UTSW |
17 |
19,394,285 (GRCm38) |
missense |
probably damaging |
0.97 |
|
PIT4382001:Vmn2r99
|
UTSW |
17 |
19,394,343 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0196:Vmn2r99
|
UTSW |
17 |
19,394,573 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0720:Vmn2r99
|
UTSW |
17 |
19,379,043 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1501:Vmn2r99
|
UTSW |
17 |
19,362,259 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R1519:Vmn2r99
|
UTSW |
17 |
19,380,060 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1670:Vmn2r99
|
UTSW |
17 |
19,362,252 (GRCm38) |
missense |
probably benign |
0.37 |
|
R1682:Vmn2r99
|
UTSW |
17 |
19,377,945 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1873:Vmn2r99
|
UTSW |
17 |
19,362,153 (GRCm38) |
missense |
probably benign |
0.25 |
|
R1967:Vmn2r99
|
UTSW |
17 |
19,378,815 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2101:Vmn2r99
|
UTSW |
17 |
19,377,991 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2474:Vmn2r99
|
UTSW |
17 |
19,378,629 (GRCm38) |
missense |
probably benign |
0.04 |
|
R2519:Vmn2r99
|
UTSW |
17 |
19,378,708 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3911:Vmn2r99
|
UTSW |
17 |
19,394,373 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R3947:Vmn2r99
|
UTSW |
17 |
19,378,990 (GRCm38) |
missense |
probably benign |
0.40 |
|
R3949:Vmn2r99
|
UTSW |
17 |
19,378,990 (GRCm38) |
missense |
probably benign |
0.40 |
|
R4016:Vmn2r99
|
UTSW |
17 |
19,378,570 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4413:Vmn2r99
|
UTSW |
17 |
19,379,260 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4594:Vmn2r99
|
UTSW |
17 |
19,393,662 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4999:Vmn2r99
|
UTSW |
17 |
19,362,135 (GRCm38) |
start codon destroyed |
probably null |
0.96 |
|
R5206:Vmn2r99
|
UTSW |
17 |
19,378,606 (GRCm38) |
missense |
probably benign |
0.40 |
|
R5362:Vmn2r99
|
UTSW |
17 |
19,379,339 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5377:Vmn2r99
|
UTSW |
17 |
19,379,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5455:Vmn2r99
|
UTSW |
17 |
19,394,146 (GRCm38) |
nonsense |
probably null |
|
|
R6021:Vmn2r99
|
UTSW |
17 |
19,377,948 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6059:Vmn2r99
|
UTSW |
17 |
19,378,980 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6214:Vmn2r99
|
UTSW |
17 |
19,382,558 (GRCm38) |
missense |
probably benign |
0.19 |
|
R6215:Vmn2r99
|
UTSW |
17 |
19,382,558 (GRCm38) |
missense |
probably benign |
0.19 |
|
R6313:Vmn2r99
|
UTSW |
17 |
19,382,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6646:Vmn2r99
|
UTSW |
17 |
19,380,031 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6810:Vmn2r99
|
UTSW |
17 |
19,380,034 (GRCm38) |
missense |
probably benign |
0.20 |
|
R6885:Vmn2r99
|
UTSW |
17 |
19,380,195 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R6991:Vmn2r99
|
UTSW |
17 |
19,378,110 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7060:Vmn2r99
|
UTSW |
17 |
19,394,564 (GRCm38) |
nonsense |
probably null |
|
|
R7090:Vmn2r99
|
UTSW |
17 |
19,393,710 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7094:Vmn2r99
|
UTSW |
17 |
19,379,311 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7449:Vmn2r99
|
UTSW |
17 |
19,379,145 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7789:Vmn2r99
|
UTSW |
17 |
19,393,817 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R8039:Vmn2r99
|
UTSW |
17 |
19,380,040 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8493:Vmn2r99
|
UTSW |
17 |
19,393,758 (GRCm38) |
missense |
probably benign |
0.15 |
|
R8511:Vmn2r99
|
UTSW |
17 |
19,394,181 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8715:Vmn2r99
|
UTSW |
17 |
19,393,660 (GRCm38) |
critical splice acceptor site |
probably benign |
|
|
R9462:Vmn2r99
|
UTSW |
17 |
19,378,126 (GRCm38) |
nonsense |
probably null |
|
|
R9681:Vmn2r99
|
UTSW |
17 |
19,378,627 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9737:Vmn2r99
|
UTSW |
17 |
19,362,301 (GRCm38) |
missense |
probably benign |
|
|
Z1088:Vmn2r99
|
UTSW |
17 |
19,379,301 (GRCm38) |
missense |
probably benign |
0.18 |
|
| Posted On |
2014-01-21 |
Incidental Mutation