Incidental Mutation 'IGL02891:Vmn2r99'
ID 363170
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r99
Ensembl Gene ENSMUSG00000090304
Gene Name vomeronasal 2, receptor 99
Synonyms EG665376
Accession Numbers
Essential gene? Probably non essential (E-score: 0.164) question?
Stock # IGL02891
Quality Score
Status
Chromosome 17
Chromosomal Location 19582397-19614852 bp(+) (GRCm39)
Type of Mutation nonsense
DNA Base Change (assembly) G to A at 19598952 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Tryptophan to Stop codon at position 212 (W212*)
Ref Sequence ENSEMBL: ENSMUSP00000156067 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000176107] [ENSMUST00000231989]
AlphaFold H3BK37
Predicted Effect probably null
Transcript: ENSMUST00000176107
AA Change: W212*
SMART Domains Protein: ENSMUSP00000135236
Gene: ENSMUSG00000090304
AA Change: W212*

DomainStartEndE-ValueType
signal peptide 1 19 N/A INTRINSIC
Pfam:ANF_receptor 81 448 5.7e-33 PFAM
Pfam:NCD3G 508 561 1.8e-21 PFAM
Pfam:7tm_3 593 829 4.6e-52 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000231989
AA Change: W212*
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca17 A G 17: 24,500,340 (GRCm39) S1284P probably damaging Het
Adgrf1 T C 17: 43,622,052 (GRCm39) V763A probably damaging Het
Adhfe1 T A 1: 9,628,396 (GRCm39) M256K probably benign Het
Afg2a T A 3: 37,480,341 (GRCm39) V130D probably damaging Het
Chit1 A G 1: 134,073,048 (GRCm39) S125G probably benign Het
Clu T A 14: 66,213,433 (GRCm39) F273Y probably damaging Het
Dgki T C 6: 36,890,676 (GRCm39) D869G probably benign Het
Elapor1 C T 3: 108,371,708 (GRCm39) R672Q probably benign Het
Emx1 T C 6: 85,181,067 (GRCm39) probably benign Het
Ercc2 T G 7: 19,127,211 (GRCm39) F316C probably damaging Het
Fam81a A G 9: 70,017,558 (GRCm39) L129P probably damaging Het
Fat4 T A 3: 39,005,422 (GRCm39) N1940K probably damaging Het
Fbxl13 G A 5: 21,727,098 (GRCm39) probably benign Het
Ift70b C T 2: 75,767,404 (GRCm39) V450M possibly damaging Het
Kcnt2 T A 1: 140,502,544 (GRCm39) D879E probably damaging Het
Kti12 T G 4: 108,705,730 (GRCm39) S215A probably benign Het
Lama1 G A 17: 68,111,531 (GRCm39) G2261R probably damaging Het
Ntn5 G T 7: 45,335,648 (GRCm39) L26F probably damaging Het
Nwd2 A G 5: 63,882,570 (GRCm39) N74S possibly damaging Het
Or12d17 T A 17: 37,777,835 (GRCm39) V246E probably damaging Het
Or2d3c A G 7: 106,526,288 (GRCm39) V126A probably damaging Het
Phactr4 T C 4: 132,114,334 (GRCm39) D20G probably damaging Het
Ptpn23 G A 9: 110,217,088 (GRCm39) Q923* probably null Het
Rfx6 T A 10: 51,599,942 (GRCm39) S333T possibly damaging Het
Skint10 T A 4: 112,586,023 (GRCm39) I198F probably benign Het
Taf3 G A 2: 9,926,038 (GRCm39) P647L probably damaging Het
Tbcb T C 7: 29,932,859 (GRCm39) probably benign Het
Tmem63c T C 12: 87,118,042 (GRCm39) F216L probably benign Het
Uba5 A G 9: 103,931,392 (GRCm39) probably benign Het
Usp34 C A 11: 23,437,166 (GRCm39) Q217K probably benign Het
Vmn1r202 G A 13: 22,685,640 (GRCm39) T259I probably benign Het
Zfp687 G T 3: 94,919,257 (GRCm39) P172T probably damaging Het
Other mutations in Vmn2r99
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00503:Vmn2r99 APN 17 19,599,116 (GRCm39) missense probably benign 0.01
IGL01113:Vmn2r99 APN 17 19,614,518 (GRCm39) missense probably benign 0.20
IGL01138:Vmn2r99 APN 17 19,602,885 (GRCm39) missense probably damaging 0.97
IGL01646:Vmn2r99 APN 17 19,613,920 (GRCm39) splice site probably benign
IGL01769:Vmn2r99 APN 17 19,600,377 (GRCm39) missense probably damaging 1.00
IGL02112:Vmn2r99 APN 17 19,600,494 (GRCm39) missense probably null 0.99
IGL03132:Vmn2r99 APN 17 19,598,485 (GRCm39) nonsense probably null
FR4548:Vmn2r99 UTSW 17 19,614,547 (GRCm39) missense probably damaging 0.97
FR4976:Vmn2r99 UTSW 17 19,614,547 (GRCm39) missense probably damaging 0.97
PIT4382001:Vmn2r99 UTSW 17 19,614,605 (GRCm39) missense probably damaging 1.00
R0196:Vmn2r99 UTSW 17 19,614,835 (GRCm39) missense probably benign 0.00
R0720:Vmn2r99 UTSW 17 19,599,305 (GRCm39) missense probably benign 0.00
R1501:Vmn2r99 UTSW 17 19,582,521 (GRCm39) missense possibly damaging 0.93
R1519:Vmn2r99 UTSW 17 19,600,322 (GRCm39) missense probably benign 0.00
R1670:Vmn2r99 UTSW 17 19,582,514 (GRCm39) missense probably benign 0.37
R1682:Vmn2r99 UTSW 17 19,598,207 (GRCm39) missense probably damaging 0.97
R1873:Vmn2r99 UTSW 17 19,582,415 (GRCm39) missense probably benign 0.25
R1967:Vmn2r99 UTSW 17 19,599,077 (GRCm39) missense probably benign 0.01
R2101:Vmn2r99 UTSW 17 19,598,253 (GRCm39) missense probably damaging 1.00
R2474:Vmn2r99 UTSW 17 19,598,891 (GRCm39) missense probably benign 0.04
R2519:Vmn2r99 UTSW 17 19,598,970 (GRCm39) missense probably damaging 0.99
R3911:Vmn2r99 UTSW 17 19,614,635 (GRCm39) missense possibly damaging 0.92
R3947:Vmn2r99 UTSW 17 19,599,252 (GRCm39) missense probably benign 0.40
R3949:Vmn2r99 UTSW 17 19,599,252 (GRCm39) missense probably benign 0.40
R4016:Vmn2r99 UTSW 17 19,598,832 (GRCm39) missense possibly damaging 0.86
R4413:Vmn2r99 UTSW 17 19,599,522 (GRCm39) missense probably damaging 1.00
R4594:Vmn2r99 UTSW 17 19,613,924 (GRCm39) missense probably damaging 1.00
R4999:Vmn2r99 UTSW 17 19,582,397 (GRCm39) start codon destroyed probably null 0.96
R5206:Vmn2r99 UTSW 17 19,598,868 (GRCm39) missense probably benign 0.40
R5362:Vmn2r99 UTSW 17 19,599,601 (GRCm39) missense probably benign 0.00
R5377:Vmn2r99 UTSW 17 19,599,531 (GRCm39) missense probably damaging 1.00
R5455:Vmn2r99 UTSW 17 19,614,408 (GRCm39) nonsense probably null
R6021:Vmn2r99 UTSW 17 19,598,210 (GRCm39) missense probably damaging 1.00
R6059:Vmn2r99 UTSW 17 19,599,242 (GRCm39) missense probably benign 0.00
R6214:Vmn2r99 UTSW 17 19,602,820 (GRCm39) missense probably benign 0.19
R6215:Vmn2r99 UTSW 17 19,602,820 (GRCm39) missense probably benign 0.19
R6313:Vmn2r99 UTSW 17 19,602,867 (GRCm39) missense probably damaging 1.00
R6646:Vmn2r99 UTSW 17 19,600,293 (GRCm39) missense probably damaging 1.00
R6810:Vmn2r99 UTSW 17 19,600,296 (GRCm39) missense probably benign 0.20
R6885:Vmn2r99 UTSW 17 19,600,457 (GRCm39) missense possibly damaging 0.52
R6991:Vmn2r99 UTSW 17 19,598,372 (GRCm39) missense probably benign 0.03
R7060:Vmn2r99 UTSW 17 19,614,826 (GRCm39) nonsense probably null
R7090:Vmn2r99 UTSW 17 19,613,972 (GRCm39) missense possibly damaging 0.83
R7094:Vmn2r99 UTSW 17 19,599,573 (GRCm39) missense probably benign 0.00
R7449:Vmn2r99 UTSW 17 19,599,407 (GRCm39) missense probably benign 0.01
R7789:Vmn2r99 UTSW 17 19,614,079 (GRCm39) missense possibly damaging 0.91
R8039:Vmn2r99 UTSW 17 19,600,302 (GRCm39) missense probably benign 0.00
R8493:Vmn2r99 UTSW 17 19,614,020 (GRCm39) missense probably benign 0.15
R8511:Vmn2r99 UTSW 17 19,614,443 (GRCm39) missense probably damaging 1.00
R8715:Vmn2r99 UTSW 17 19,613,922 (GRCm39) critical splice acceptor site probably benign
R9462:Vmn2r99 UTSW 17 19,598,388 (GRCm39) nonsense probably null
R9681:Vmn2r99 UTSW 17 19,598,889 (GRCm39) missense probably damaging 1.00
R9737:Vmn2r99 UTSW 17 19,582,563 (GRCm39) missense probably benign
Z1088:Vmn2r99 UTSW 17 19,599,563 (GRCm39) missense probably benign 0.18
Posted On 2015-12-18