Mutagenetix > Incidental Mutation

Incidental Mutation 'R4586:Dnhd1'

344111

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

041807-MU

Accession Numbers

Variant 1:ENSMUST00000145988; OTTMUST00000062891; Variant 2: ENSMUST00000106773; Variant 3: ENSMUST00000106776; Variant 4: ENSMUST00000163171; Variant 5: ENSMUST00000142363;OTTMUST00000062869; Variant 6: ENSMUST00000142874; OTTMUST00000062870; Variant 7: ENSMUST00000128388; OTTMUST00000062892; MGI:1924755

Essential gene?

Probably non essential (E-score: 0.077) question?

Stock #

R4586 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

105650827-105721799 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 105678049 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Proline at position 735 (L735P)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000106776] [ENSMUST00000142874] [ENSMUST00000145988] [ENSMUST00000210312]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000106776

SMART Domains

Protein: ENSMUSP00000102388
Gene: ENSMUSG00000030882

Domain	Start	End	E-Value	Type
low complexity region	205	224	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000128388

Predicted Effect

probably benign
Transcript: ENSMUST00000142874

Predicted Effect

probably damaging
Transcript: ENSMUST00000145988
AA Change: L735P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: L735P

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000210312

Meta Mutation Damage Score

0.6755

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.3%
20x: 95.3%

Validation Efficiency

100% (96/96)

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 84 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110004E09Rik	A	T	16: 90,927,426 (GRCm38)	V136D	probably damaging	Het
Akap9	T	C	5: 3,976,151 (GRCm38)	S1269P	probably benign	Het
Aqr	T	C	2: 114,112,577 (GRCm38)	T1172A	probably benign	Het
Art2a-ps	A	T	7: 101,554,749 (GRCm38)	L194*	probably null	Het
Atrn	T	C	2: 130,982,042 (GRCm38)	F967S	probably damaging	Het
Btnl1	A	G	17: 34,382,462 (GRCm38)	D323G	probably damaging	Het
Cadps	C	A	14: 12,505,808 (GRCm38)	C754F	probably damaging	Het
Ccdc7b	A	G	8: 129,110,920 (GRCm38)	T131A	probably benign	Het
Cic	A	T	7: 25,272,778 (GRCm38)	I645L	probably benign	Het
Clca1	C	A	3: 145,016,858 (GRCm38)	C251F	probably damaging	Het
Cldn16	A	T	16: 26,477,558 (GRCm38)	T95S	probably benign	Het
Cntnap4	C	T	8: 112,810,710 (GRCm38)	H738Y	probably benign	Het
Col8a2	A	T	4: 126,311,019 (GRCm38)		probably benign	Het
Corin	A	T	5: 72,329,699 (GRCm38)	V706D	probably damaging	Het
Cuzd1	G	A	7: 131,314,800 (GRCm38)	P310L	probably damaging	Het
Cyp4a12a	T	C	4: 115,327,312 (GRCm38)	F295L	probably benign	Het
Cyp4a12b	T	G	4: 115,432,506 (GRCm38)	M190R	probably damaging	Het
Dagla	A	G	19: 10,271,009 (GRCm38)	Y96H	probably damaging	Het
Dapp1	T	C	3: 137,939,171 (GRCm38)	Q148R	probably benign	Het
Dcaf17	T	A	2: 71,088,580 (GRCm38)	S499R	probably benign	Het
Ddx27	T	A	2: 167,019,984 (GRCm38)	D135E	probably benign	Het
Defb3	A	T	8: 19,295,156 (GRCm38)	I43F	possibly damaging	Het
Dnajc10	T	G	2: 80,347,778 (GRCm38)	F710V	probably damaging	Het
Dnmt1	G	A	9: 20,926,693 (GRCm38)	P242S	probably benign	Het
Dync1h1	G	A	12: 110,649,483 (GRCm38)	D3022N	probably benign	Het
Ep400	G	A	5: 110,753,859 (GRCm38)	T464I	probably damaging	Het
Epc1	T	C	18: 6,449,138 (GRCm38)	N453S	possibly damaging	Het
Eral1	A	T	11: 78,078,304 (GRCm38)	N123K	probably damaging	Het
Ercc5	G	A	1: 44,158,857 (GRCm38)	V145I	probably benign	Het
Evc	A	G	5: 37,323,713 (GRCm38)	S263P	probably damaging	Het
Fancc	A	T	13: 63,347,564 (GRCm38)	M182K	probably benign	Het
Fbxl3	G	T	14: 103,083,090 (GRCm38)	A355E	probably damaging	Het
Fig4	A	C	10: 41,188,632 (GRCm38)	S872A	probably damaging	Het
Gm14393	C	A	2: 175,062,704 (GRCm38)		probably benign	Het
Gm16432	A	G	1: 178,122,785 (GRCm38)	D734G	possibly damaging	Het
Gm27013	A	T	6: 130,521,040 (GRCm38)		noncoding transcript	Het
Gprc5a	T	A	6: 135,083,452 (GRCm38)	M313K	probably benign	Het
H2-T3	T	C	17: 36,189,344 (GRCm38)		probably null	Het
Hap1	G	A	11: 100,354,724 (GRCm38)	T138M	probably benign	Het
Hist1h2ak	T	C	13: 21,753,712 (GRCm38)	N39S	possibly damaging	Het
Hook3	T	G	8: 26,032,011 (GRCm38)	K679T	probably damaging	Het
Ints2	G	T	11: 86,249,275 (GRCm38)	R244S	probably damaging	Het
Itgb4	T	C	11: 115,993,325 (GRCm38)	V945A	probably damaging	Het
Itih2	C	T	2: 10,110,400 (GRCm38)	S387N	probably benign	Het
Jmjd7	T	A	2: 120,032,168 (GRCm38)	M306K	probably benign	Het
Klra2	T	A	6: 131,230,157 (GRCm38)	D163V	probably benign	Het
Kmo	T	A	1: 175,650,572 (GRCm38)	M208K	probably damaging	Het
Kmo	G	T	1: 175,650,573 (GRCm38)	M208I	possibly damaging	Het
Masp2	A	G	4: 148,613,901 (GRCm38)	T480A	probably damaging	Het
Mogs	G	T	6: 83,118,638 (GRCm38)	R812L	possibly damaging	Het
Mrpl43	A	G	19: 45,005,889 (GRCm38)	I97T	possibly damaging	Het
Myoz1	A	G	14: 20,650,595 (GRCm38)	W185R	probably damaging	Het
Ncam2	T	A	16: 81,465,569 (GRCm38)	H303Q	probably benign	Het
Nufip2	T	C	11: 77,741,728 (GRCm38)	V690A	unknown	Het
Obox1	A	T	7: 15,556,227 (GRCm38)	N165I	possibly damaging	Het
Olfr1218	T	G	2: 89,055,154 (GRCm38)	I91L	possibly damaging	Het
Olfr3	C	T	2: 36,812,525 (GRCm38)	C189Y	probably damaging	Het
Olfr32	T	A	2: 90,138,214 (GRCm38)	E308D	probably benign	Het
Olfr781	A	G	10: 129,333,273 (GRCm38)	T131A	probably benign	Het
Pex1	A	G	5: 3,633,885 (GRCm38)	Y1127C	probably damaging	Het
Pno1	T	C	11: 17,211,438 (GRCm38)	K24E	probably benign	Het
Qdpr	T	A	5: 45,439,327 (GRCm38)	N165I	possibly damaging	Het
Robo2	A	G	16: 73,961,873 (GRCm38)	V674A	probably damaging	Het
Runx1t1	A	T	4: 13,889,864 (GRCm38)	T598S	unknown	Het
Samd11	A	G	4: 156,249,432 (GRCm38)	L174P	probably damaging	Het
Scn2a	T	A	2: 65,743,051 (GRCm38)		probably null	Het
Slc4a1	G	T	11: 102,361,419 (GRCm38)		probably benign	Het
Snx25	A	T	8: 46,116,437 (GRCm38)		probably benign	Het
Sox2	A	G	3: 34,651,044 (GRCm38)	N210S	probably benign	Het
Spag6	T	C	2: 18,732,147 (GRCm38)		probably null	Het
Speer4b	A	T	5: 27,498,038 (GRCm38)	L154Q	probably null	Het
Stt3a	T	A	9: 36,741,793 (GRCm38)	Q531L	probably damaging	Het
Tcl1	A	C	12: 105,217,508 (GRCm38)		probably benign	Het
Trip11	A	T	12: 101,883,341 (GRCm38)	M1488K	possibly damaging	Het
Ttn	T	C	2: 76,968,403 (GRCm38)	H509R	probably benign	Het
Ulk3	C	T	9: 57,594,310 (GRCm38)	L425F	possibly damaging	Het
Vmn1r238	T	A	18: 3,123,294 (GRCm38)	K40M	probably damaging	Het
Vopp1	G	A	6: 57,754,548 (GRCm38)	P153S	probably damaging	Het
Wdyhv1	A	T	15: 58,148,344 (GRCm38)	I34F	probably damaging	Het
Zbtb42	C	T	12: 112,680,542 (GRCm38)	R384W	probably damaging	Het
Zfp14	G	T	7: 30,038,916 (GRCm38)	Q215K	probably damaging	Het
Zfp473	A	T	7: 44,732,952 (GRCm38)	Y651*	probably null	Het
Zfp735	G	T	11: 73,689,724 (GRCm38)	E16D	possibly damaging	Het
Zfp846	G	T	9: 20,593,513 (GRCm38)	C223F	probably damaging	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,677,995 (GRCm38)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,657,211 (GRCm38)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,692,675 (GRCm38)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,721,688 (GRCm38)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,713,909 (GRCm38)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,720,942 (GRCm38)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,713,754 (GRCm38)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,652,030 (GRCm38)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,721,215 (GRCm38)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,678,309 (GRCm38)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,720,802 (GRCm38)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,721,744 (GRCm38)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,721,481 (GRCm38)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,720,741 (GRCm38)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,719,882 (GRCm38)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,714,475 (GRCm38)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,713,733 (GRCm38)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,655,723 (GRCm38)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,668,514 (GRCm38)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,720,924 (GRCm38)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,721,531 (GRCm38)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,720,114 (GRCm38)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,674,444 (GRCm38)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,720,788 (GRCm38)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,694,395 (GRCm38)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,714,045 (GRCm38)	missense	probably damaging	1.00
R0607:Dnhd1	UTSW	7	105,720,788 (GRCm38)	missense	probably benign	0.04
R0631:Dnhd1	UTSW	7	105,651,624 (GRCm38)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,696,464 (GRCm38)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,695,751 (GRCm38)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,693,704 (GRCm38)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,696,464 (GRCm38)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,651,906 (GRCm38)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,709,171 (GRCm38)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,713,031 (GRCm38)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,696,899 (GRCm38)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,694,153 (GRCm38)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,720,124 (GRCm38)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,721,273 (GRCm38)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,668,463 (GRCm38)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,693,660 (GRCm38)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,704,148 (GRCm38)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,713,706 (GRCm38)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,703,206 (GRCm38)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,714,281 (GRCm38)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,693,828 (GRCm38)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,714,920 (GRCm38)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,693,972 (GRCm38)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,655,767 (GRCm38)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,704,205 (GRCm38)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,713,407 (GRCm38)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,673,854 (GRCm38)	missense	probably damaging	0.96
R1925:Dnhd1	UTSW	7	105,652,252 (GRCm38)	missense	probably damaging	1.00
R1934:Dnhd1	UTSW	7	105,708,582 (GRCm38)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,673,976 (GRCm38)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,673,976 (GRCm38)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,704,921 (GRCm38)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,677,971 (GRCm38)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,693,721 (GRCm38)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,703,772 (GRCm38)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,705,399 (GRCm38)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,674,421 (GRCm38)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,710,090 (GRCm38)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,703,467 (GRCm38)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,693,664 (GRCm38)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,720,231 (GRCm38)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,712,559 (GRCm38)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,720,229 (GRCm38)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,696,565 (GRCm38)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,694,761 (GRCm38)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,694,761 (GRCm38)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,694,785 (GRCm38)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,713,122 (GRCm38)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,714,838 (GRCm38)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,709,588 (GRCm38)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,693,954 (GRCm38)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,712,998 (GRCm38)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,693,954 (GRCm38)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,696,728 (GRCm38)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,651,956 (GRCm38)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,657,166 (GRCm38)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,678,049 (GRCm38)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,714,030 (GRCm38)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,715,446 (GRCm38)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,703,644 (GRCm38)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,655,741 (GRCm38)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4732:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,673,849 (GRCm38)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,674,444 (GRCm38)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,721,117 (GRCm38)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,714,281 (GRCm38)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,703,964 (GRCm38)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,714,808 (GRCm38)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,656,957 (GRCm38)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,713,633 (GRCm38)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,713,076 (GRCm38)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,693,697 (GRCm38)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,713,440 (GRCm38)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,714,552 (GRCm38)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,696,460 (GRCm38)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,703,923 (GRCm38)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,685,761 (GRCm38)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,674,037 (GRCm38)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,674,037 (GRCm38)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,714,482 (GRCm38)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,714,437 (GRCm38)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,713,684 (GRCm38)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,710,123 (GRCm38)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,714,156 (GRCm38)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,714,821 (GRCm38)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,703,209 (GRCm38)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,674,188 (GRCm38)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,705,010 (GRCm38)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,655,774 (GRCm38)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,719,895 (GRCm38)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,720,181 (GRCm38)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,695,748 (GRCm38)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,720,504 (GRCm38)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,713,987 (GRCm38)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,709,440 (GRCm38)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,704,048 (GRCm38)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,652,009 (GRCm38)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,693,370 (GRCm38)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,694,066 (GRCm38)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,694,610 (GRCm38)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,677,886 (GRCm38)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,703,799 (GRCm38)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,685,692 (GRCm38)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,703,875 (GRCm38)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,720,637 (GRCm38)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,703,373 (GRCm38)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,719,930 (GRCm38)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,703,728 (GRCm38)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,678,266 (GRCm38)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,687,377 (GRCm38)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,715,563 (GRCm38)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,713,688 (GRCm38)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,704,585 (GRCm38)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,714,210 (GRCm38)	missense	probably damaging	1.00
R7022:Dnhd1	UTSW	7	105,720,798 (GRCm38)	missense	probably benign	0.36
R7053:Dnhd1	UTSW	7	105,694,954 (GRCm38)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,715,261 (GRCm38)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,708,532 (GRCm38)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,713,985 (GRCm38)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,693,766 (GRCm38)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,710,027 (GRCm38)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,694,993 (GRCm38)	missense	probably damaging	0.98
R7326:Dnhd1	UTSW	7	105,720,930 (GRCm38)	missense	probably damaging	0.96
R7345:Dnhd1	UTSW	7	105,703,967 (GRCm38)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,710,123 (GRCm38)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,705,297 (GRCm38)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,696,048 (GRCm38)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,709,561 (GRCm38)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,720,912 (GRCm38)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,678,309 (GRCm38)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,674,268 (GRCm38)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,684,087 (GRCm38)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,713,963 (GRCm38)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,651,624 (GRCm38)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,705,265 (GRCm38)	missense	probably damaging	1.00
R7767:Dnhd1	UTSW	7	105,694,610 (GRCm38)	missense	probably benign	0.38
R7768:Dnhd1	UTSW	7	105,721,095 (GRCm38)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,677,915 (GRCm38)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,703,439 (GRCm38)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,668,514 (GRCm38)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,678,004 (GRCm38)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,694,788 (GRCm38)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,678,024 (GRCm38)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,677,866 (GRCm38)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,703,343 (GRCm38)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,682,794 (GRCm38)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,694,280 (GRCm38)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,652,123 (GRCm38)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,693,967 (GRCm38)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,721,516 (GRCm38)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,713,648 (GRCm38)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,683,697 (GRCm38)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,714,647 (GRCm38)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,694,779 (GRCm38)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,692,645 (GRCm38)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,709,321 (GRCm38)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,674,035 (GRCm38)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,692,726 (GRCm38)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,684,063 (GRCm38)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,683,966 (GRCm38)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,651,884 (GRCm38)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,714,141 (GRCm38)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,683,966 (GRCm38)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,720,599 (GRCm38)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,704,277 (GRCm38)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,720,599 (GRCm38)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,712,765 (GRCm38)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,695,016 (GRCm38)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,657,247 (GRCm38)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,703,682 (GRCm38)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,651,597 (GRCm38)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,704,502 (GRCm38)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,703,682 (GRCm38)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,704,972 (GRCm38)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,695,533 (GRCm38)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,704,266 (GRCm38)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,704,135 (GRCm38)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,694,927 (GRCm38)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,686,566 (GRCm38)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,714,222 (GRCm38)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,703,928 (GRCm38)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,720,249 (GRCm38)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,704,033 (GRCm38)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,703,710 (GRCm38)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,693,330 (GRCm38)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,712,727 (GRCm38)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,703,036 (GRCm38)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,678,299 (GRCm38)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,668,547 (GRCm38)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,703,580 (GRCm38)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,682,841 (GRCm38)	missense	possibly damaging	0.90

Predicted Primers

PCR Primer
(F):5'- ATTCCTGATGCCCAAGTTTCATG -3'
(R):5'- CTCCAGGCTTTCAGGAACTC -3'

Sequencing Primer
(F):5'- CCTGATGCCCAAGTTTCATGGAAAG -3'
(R):5'- GGCTTTCAGGAACTCATAGATGCC -3'

Posted On

2015-09-24