Incidental Mutation 'R0514:Tmprss15'
| ID |
48153 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tmprss15
|
| Ensembl Gene |
ENSMUSG00000022857 |
| Gene Name |
transmembrane protease, serine 15 |
| Synonyms |
Prss7, enterokinase, enteropeptidase, A130097D21Rik |
| MMRRC Submission |
038708-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0514 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
78749896-78887985 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 78765155 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 816
(S816T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000023566
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023566]
[ENSMUST00000060402]
|
| AlphaFold |
P97435 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000023566
AA Change: S816T
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000023566
Gene: ENSMUSG00000022857
AA Change: S816T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
21 |
43 |
N/A |
INTRINSIC |
|
SEA
|
52 |
172 |
1.62e-22 |
SMART |
|
LDLa
|
228 |
268 |
1.74e-4 |
SMART |
|
CUB
|
270 |
379 |
1.54e-11 |
SMART |
|
MAM
|
387 |
549 |
7.33e-54 |
SMART |
|
low complexity region
|
551 |
567 |
N/A |
INTRINSIC |
|
CUB
|
569 |
679 |
1.72e-32 |
SMART |
|
LDLa
|
687 |
724 |
7.32e-12 |
SMART |
|
SR
|
723 |
813 |
3.12e-5 |
SMART |
|
Tryp_SPc
|
829 |
1064 |
1.48e-95 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000060402
AA Change: S801T
PolyPhen 2
Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000052034
Gene: ENSMUSG00000022857
AA Change: S801T
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
21 |
43 |
N/A |
INTRINSIC |
|
SEA
|
52 |
172 |
1.62e-22 |
SMART |
|
LDLa
|
213 |
253 |
1.74e-4 |
SMART |
|
CUB
|
255 |
364 |
1.54e-11 |
SMART |
|
MAM
|
372 |
534 |
7.33e-54 |
SMART |
|
low complexity region
|
536 |
552 |
N/A |
INTRINSIC |
|
CUB
|
554 |
664 |
1.72e-32 |
SMART |
|
LDLa
|
672 |
709 |
7.32e-12 |
SMART |
|
SR
|
708 |
798 |
3.12e-5 |
SMART |
|
Tryp_SPc
|
814 |
1049 |
1.48e-95 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152173
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes an enzyme that proteolytically activates the pancreatic proenzyme trypsinogen, converting it into trypsin. The encoded protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acp3 |
T |
A |
9: 104,197,177 (GRCm39) |
Y154F |
probably damaging |
Het |
| Acsl6 |
A |
T |
11: 54,241,406 (GRCm39) |
D579V |
probably damaging |
Het |
| Adamts18 |
C |
T |
8: 114,465,401 (GRCm39) |
|
probably null |
Het |
| Adamts20 |
A |
T |
15: 94,168,257 (GRCm39) |
V1882D |
probably damaging |
Het |
| Add3 |
A |
T |
19: 53,225,274 (GRCm39) |
K465* |
probably null |
Het |
| Ago1 |
T |
G |
4: 126,333,388 (GRCm39) |
I524L |
probably benign |
Het |
| Akr1c18 |
A |
G |
13: 4,187,190 (GRCm39) |
M208T |
probably benign |
Het |
| Anapc1 |
C |
A |
2: 128,474,575 (GRCm39) |
L1413F |
probably damaging |
Het |
| Arid4b |
A |
T |
13: 14,358,902 (GRCm39) |
D646V |
probably damaging |
Het |
| Arnt2 |
T |
C |
7: 83,954,067 (GRCm39) |
E261G |
probably benign |
Het |
| Bccip |
C |
T |
7: 133,320,859 (GRCm39) |
T211I |
possibly damaging |
Het |
| Bsn |
T |
C |
9: 108,002,981 (GRCm39) |
S475G |
probably benign |
Het |
| Cdh26 |
G |
A |
2: 178,108,621 (GRCm39) |
|
probably null |
Het |
| Ceacam2 |
A |
G |
7: 25,220,356 (GRCm39) |
F414S |
probably benign |
Het |
| Cep43 |
A |
G |
17: 8,410,266 (GRCm39) |
N342S |
possibly damaging |
Het |
| Cfb |
T |
C |
17: 35,079,874 (GRCm39) |
R172G |
probably damaging |
Het |
| Cntnap5b |
A |
C |
1: 99,700,511 (GRCm39) |
T8P |
probably benign |
Het |
| Cpne9 |
A |
T |
6: 113,266,974 (GRCm39) |
I136L |
probably damaging |
Het |
| Crtc1 |
A |
T |
8: 70,855,079 (GRCm39) |
|
probably null |
Het |
| Dcdc2a |
A |
T |
13: 25,303,369 (GRCm39) |
H300L |
probably benign |
Het |
| Dhdh |
C |
T |
7: 45,138,130 (GRCm39) |
V20M |
probably benign |
Het |
| Dhx34 |
T |
C |
7: 15,944,462 (GRCm39) |
Q584R |
probably benign |
Het |
| Dis3l2 |
A |
G |
1: 86,974,814 (GRCm39) |
Y701C |
probably damaging |
Het |
| Dmrt2 |
T |
C |
19: 25,653,019 (GRCm39) |
|
probably null |
Het |
| Dnah5 |
A |
G |
15: 28,366,467 (GRCm39) |
T2727A |
probably damaging |
Het |
| Dop1a |
A |
G |
9: 86,402,787 (GRCm39) |
E1329G |
probably damaging |
Het |
| Evpl |
A |
G |
11: 116,114,117 (GRCm39) |
V1191A |
probably damaging |
Het |
| Fhl4 |
T |
C |
10: 84,934,250 (GRCm39) |
D177G |
probably damaging |
Het |
| Gask1a |
A |
G |
9: 121,807,418 (GRCm39) |
T521A |
possibly damaging |
Het |
| Heg1 |
A |
G |
16: 33,547,126 (GRCm39) |
T662A |
possibly damaging |
Het |
| Ifih1 |
A |
G |
2: 62,453,735 (GRCm39) |
|
probably null |
Het |
| Il13 |
T |
C |
11: 53,523,345 (GRCm39) |
R87G |
possibly damaging |
Het |
| Kcnc3 |
T |
A |
7: 44,245,352 (GRCm39) |
Y547* |
probably null |
Het |
| Krt81 |
C |
A |
15: 101,361,508 (GRCm39) |
R24L |
possibly damaging |
Het |
| Lama1 |
G |
A |
17: 68,071,693 (GRCm39) |
G860D |
probably benign |
Het |
| Lmo7 |
T |
C |
14: 102,124,609 (GRCm39) |
L356P |
probably damaging |
Het |
| Lmo7 |
A |
T |
14: 102,133,995 (GRCm39) |
K447I |
probably damaging |
Het |
| Lrp2bp |
A |
G |
8: 46,464,995 (GRCm39) |
H38R |
probably damaging |
Het |
| Magi3 |
G |
A |
3: 103,922,338 (GRCm39) |
P1460S |
probably damaging |
Het |
| Megf8 |
T |
A |
7: 25,063,728 (GRCm39) |
C2695S |
possibly damaging |
Het |
| Mrgprb2 |
T |
G |
7: 48,201,718 (GRCm39) |
S336R |
probably benign |
Het |
| Mrgprx2 |
C |
T |
7: 48,132,712 (GRCm39) |
M1I |
probably null |
Het |
| Mug2 |
T |
C |
6: 122,058,558 (GRCm39) |
L1320P |
probably damaging |
Het |
| Noxred1 |
A |
G |
12: 87,273,838 (GRCm39) |
S68P |
probably benign |
Het |
| Or51f5 |
T |
A |
7: 102,424,539 (GRCm39) |
H269Q |
probably benign |
Het |
| Or56b1b |
T |
A |
7: 108,164,879 (GRCm39) |
Y41F |
probably damaging |
Het |
| Os9 |
C |
T |
10: 126,955,508 (GRCm39) |
C123Y |
probably damaging |
Het |
| Ostf1 |
T |
A |
19: 18,573,723 (GRCm39) |
T42S |
probably benign |
Het |
| Parg |
C |
A |
14: 31,976,517 (GRCm39) |
T186K |
possibly damaging |
Het |
| Pcnx1 |
T |
A |
12: 82,041,884 (GRCm39) |
M2172K |
probably benign |
Het |
| Pip4k2a |
A |
G |
2: 18,850,747 (GRCm39) |
I360T |
probably damaging |
Het |
| Pkn2 |
T |
C |
3: 142,516,219 (GRCm39) |
D568G |
possibly damaging |
Het |
| Plch2 |
A |
G |
4: 155,083,343 (GRCm39) |
S431P |
probably damaging |
Het |
| Prl8a6 |
A |
T |
13: 27,616,990 (GRCm39) |
C233* |
probably null |
Het |
| Prox1 |
G |
A |
1: 189,893,653 (GRCm39) |
T264I |
probably damaging |
Het |
| Prr5 |
A |
G |
15: 84,586,967 (GRCm39) |
N248S |
probably benign |
Het |
| Psip1 |
A |
C |
4: 83,378,274 (GRCm39) |
S407R |
probably damaging |
Het |
| Rab32 |
A |
T |
10: 10,426,640 (GRCm39) |
V102E |
probably damaging |
Het |
| Rap1gap2 |
T |
G |
11: 74,279,680 (GRCm39) |
K687Q |
possibly damaging |
Het |
| Rbak |
A |
T |
5: 143,159,169 (GRCm39) |
V628E |
probably damaging |
Het |
| Rnf148 |
T |
C |
6: 23,654,792 (GRCm39) |
E68G |
possibly damaging |
Het |
| Rnf212 |
A |
T |
5: 108,897,308 (GRCm39) |
S3T |
probably damaging |
Het |
| Rrad |
T |
G |
8: 105,355,259 (GRCm39) |
I250L |
probably benign |
Het |
| Sall4 |
T |
C |
2: 168,597,625 (GRCm39) |
H405R |
probably damaging |
Het |
| Scn9a |
T |
C |
2: 66,314,022 (GRCm39) |
R1888G |
probably damaging |
Het |
| Setd5 |
G |
T |
6: 113,096,398 (GRCm39) |
E535* |
probably null |
Het |
| Slc20a1 |
C |
T |
2: 129,041,811 (GRCm39) |
S58L |
probably damaging |
Het |
| Slc31a1 |
A |
G |
4: 62,303,841 (GRCm39) |
|
probably benign |
Het |
| Slc38a11 |
G |
T |
2: 65,147,209 (GRCm39) |
Q423K |
probably benign |
Het |
| Snrpd1 |
A |
T |
18: 10,626,846 (GRCm39) |
T38S |
possibly damaging |
Het |
| Taar4 |
A |
G |
10: 23,836,780 (GRCm39) |
D130G |
probably damaging |
Het |
| Tfb2m |
C |
T |
1: 179,358,869 (GRCm39) |
R338H |
probably benign |
Het |
| Tm2d2 |
A |
G |
8: 25,512,742 (GRCm39) |
I197V |
possibly damaging |
Het |
| Tmem132a |
C |
T |
19: 10,836,355 (GRCm39) |
G725D |
probably damaging |
Het |
| Tmem67 |
T |
C |
4: 12,089,317 (GRCm39) |
T38A |
probably benign |
Het |
| Tnfrsf11a |
A |
G |
1: 105,754,717 (GRCm39) |
E263G |
probably damaging |
Het |
| Tnfrsf17 |
C |
T |
16: 11,133,191 (GRCm39) |
L90F |
probably benign |
Het |
| Tpr |
A |
G |
1: 150,278,024 (GRCm39) |
K117E |
possibly damaging |
Het |
| Trim43a |
C |
T |
9: 88,466,389 (GRCm39) |
Q5* |
probably null |
Het |
| Ubn1 |
A |
T |
16: 4,890,935 (GRCm39) |
D498V |
probably damaging |
Het |
| Vipr1 |
T |
A |
9: 121,487,115 (GRCm39) |
C63S |
probably damaging |
Het |
| Vmn1r237 |
T |
A |
17: 21,534,932 (GRCm39) |
H218Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r95 |
T |
C |
17: 18,671,844 (GRCm39) |
V527A |
probably benign |
Het |
| Vmn2r97 |
A |
T |
17: 19,134,734 (GRCm39) |
T51S |
probably benign |
Het |
| Vwa8 |
G |
A |
14: 79,184,629 (GRCm39) |
V376I |
probably benign |
Het |
| Wdfy4 |
T |
A |
14: 32,802,732 (GRCm39) |
T1838S |
probably benign |
Het |
| Zcwpw1 |
A |
T |
5: 137,794,945 (GRCm39) |
E47V |
probably benign |
Het |
| Zeb2 |
T |
C |
2: 44,892,659 (GRCm39) |
E130G |
possibly damaging |
Het |
| Zfp111 |
A |
G |
7: 23,898,568 (GRCm39) |
Y348H |
probably damaging |
Het |
| Zfp53 |
T |
C |
17: 21,729,271 (GRCm39) |
S435P |
probably damaging |
Het |
|
| Other mutations in Tmprss15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00331:Tmprss15
|
APN |
16 |
78,782,882 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL00477:Tmprss15
|
APN |
16 |
78,818,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01583:Tmprss15
|
APN |
16 |
78,868,149 (GRCm39) |
missense |
probably benign |
|
|
IGL01896:Tmprss15
|
APN |
16 |
78,887,678 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL02052:Tmprss15
|
APN |
16 |
78,884,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02374:Tmprss15
|
APN |
16 |
78,832,056 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02505:Tmprss15
|
APN |
16 |
78,784,629 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02632:Tmprss15
|
APN |
16 |
78,782,790 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02674:Tmprss15
|
APN |
16 |
78,798,682 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
beached
|
UTSW |
16 |
78,821,736 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
Cellulite
|
UTSW |
16 |
78,754,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
lolling
|
UTSW |
16 |
78,800,298 (GRCm39) |
missense |
probably benign |
0.26 |
|
miniature
|
UTSW |
16 |
78,854,497 (GRCm39) |
critical splice donor site |
probably null |
|
|
PIT1430001:Tmprss15
|
UTSW |
16 |
78,821,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0106:Tmprss15
|
UTSW |
16 |
78,800,277 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0106:Tmprss15
|
UTSW |
16 |
78,800,277 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0195:Tmprss15
|
UTSW |
16 |
78,831,222 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0335:Tmprss15
|
UTSW |
16 |
78,821,630 (GRCm39) |
splice site |
probably benign |
|
|
R0552:Tmprss15
|
UTSW |
16 |
78,821,637 (GRCm39) |
splice site |
probably null |
|
|
R0675:Tmprss15
|
UTSW |
16 |
78,782,838 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0739:Tmprss15
|
UTSW |
16 |
78,821,736 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1435:Tmprss15
|
UTSW |
16 |
78,818,342 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1446:Tmprss15
|
UTSW |
16 |
78,875,846 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1572:Tmprss15
|
UTSW |
16 |
78,887,717 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1708:Tmprss15
|
UTSW |
16 |
78,850,958 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1893:Tmprss15
|
UTSW |
16 |
78,868,306 (GRCm39) |
missense |
probably benign |
|
|
R2403:Tmprss15
|
UTSW |
16 |
78,854,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2866:Tmprss15
|
UTSW |
16 |
78,832,121 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2913:Tmprss15
|
UTSW |
16 |
78,759,078 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2914:Tmprss15
|
UTSW |
16 |
78,759,078 (GRCm39) |
missense |
probably benign |
0.45 |
|
R3425:Tmprss15
|
UTSW |
16 |
78,800,321 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3703:Tmprss15
|
UTSW |
16 |
78,851,030 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3916:Tmprss15
|
UTSW |
16 |
78,782,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3950:Tmprss15
|
UTSW |
16 |
78,870,074 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4332:Tmprss15
|
UTSW |
16 |
78,831,222 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4392:Tmprss15
|
UTSW |
16 |
78,821,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4515:Tmprss15
|
UTSW |
16 |
78,754,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4619:Tmprss15
|
UTSW |
16 |
78,818,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4620:Tmprss15
|
UTSW |
16 |
78,818,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4754:Tmprss15
|
UTSW |
16 |
78,851,012 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4853:Tmprss15
|
UTSW |
16 |
78,757,479 (GRCm39) |
missense |
probably benign |
|
|
R5159:Tmprss15
|
UTSW |
16 |
78,800,298 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5441:Tmprss15
|
UTSW |
16 |
78,868,335 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5824:Tmprss15
|
UTSW |
16 |
78,831,201 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5970:Tmprss15
|
UTSW |
16 |
78,854,547 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6224:Tmprss15
|
UTSW |
16 |
78,821,266 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6257:Tmprss15
|
UTSW |
16 |
78,769,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6313:Tmprss15
|
UTSW |
16 |
78,759,058 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6368:Tmprss15
|
UTSW |
16 |
78,802,945 (GRCm39) |
splice site |
probably null |
|
|
R6525:Tmprss15
|
UTSW |
16 |
78,800,266 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6587:Tmprss15
|
UTSW |
16 |
78,868,317 (GRCm39) |
missense |
probably benign |
|
|
R6894:Tmprss15
|
UTSW |
16 |
78,872,702 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Tmprss15
|
UTSW |
16 |
78,821,741 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7180:Tmprss15
|
UTSW |
16 |
78,764,886 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7324:Tmprss15
|
UTSW |
16 |
78,758,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7337:Tmprss15
|
UTSW |
16 |
78,868,164 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7558:Tmprss15
|
UTSW |
16 |
78,800,302 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R7732:Tmprss15
|
UTSW |
16 |
78,800,308 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7792:Tmprss15
|
UTSW |
16 |
78,800,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7829:Tmprss15
|
UTSW |
16 |
78,784,538 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7998:Tmprss15
|
UTSW |
16 |
78,798,731 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8009:Tmprss15
|
UTSW |
16 |
78,887,751 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8145:Tmprss15
|
UTSW |
16 |
78,757,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8183:Tmprss15
|
UTSW |
16 |
78,884,400 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8221:Tmprss15
|
UTSW |
16 |
78,821,223 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8294:Tmprss15
|
UTSW |
16 |
78,868,176 (GRCm39) |
missense |
probably benign |
|
|
R8537:Tmprss15
|
UTSW |
16 |
78,884,403 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8735:Tmprss15
|
UTSW |
16 |
78,798,702 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8858:Tmprss15
|
UTSW |
16 |
78,854,497 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8869:Tmprss15
|
UTSW |
16 |
78,750,834 (GRCm39) |
nonsense |
probably null |
|
|
R8884:Tmprss15
|
UTSW |
16 |
78,821,657 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9014:Tmprss15
|
UTSW |
16 |
78,872,691 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9075:Tmprss15
|
UTSW |
16 |
78,754,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9351:Tmprss15
|
UTSW |
16 |
78,832,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9393:Tmprss15
|
UTSW |
16 |
78,754,211 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9747:Tmprss15
|
UTSW |
16 |
78,884,400 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9767:Tmprss15
|
UTSW |
16 |
78,875,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9783:Tmprss15
|
UTSW |
16 |
78,887,890 (GRCm39) |
start gained |
probably benign |
|
|
RF005:Tmprss15
|
UTSW |
16 |
78,750,689 (GRCm39) |
makesense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCACTGCTGACAAGAGATGCACC -3'
(R):5'- ACACCGTGGGGCATTTTCTTCTG -3'
Sequencing Primer
(F):5'- GACCTGTCTCTGTGATACAAAGC -3'
(R):5'- GGCATTTTCTTCTGTGGATTTCAAC -3'
|
| Posted On |
2013-06-12 |
Incidental Mutation