Mutagenetix > Incidental Mutation

Incidental Mutation 'R6297:Dnah10'

508835

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

044464-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R6297 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

124802149-124911372 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 124852144 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 1824 (D1824G)

Ref Sequence

ENSEMBL: ENSMUSP00000062995 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000058440
AA Change: D1824G

PolyPhen 2 Score 0.545 (Sensitivity: 0.88; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: D1824G

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000141137
AA Change: D1767G

PolyPhen 2 Score 0.320 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: D1767G

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Meta Mutation Damage Score

0.1795

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.5%
20x: 98.4%

Validation Efficiency

98% (45/46)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca4	T	C	3: 121,926,179 (GRCm39)	V1205A	probably benign	Het
Adgra3	G	A	5: 50,118,189 (GRCm39)	P1120S	probably benign	Het
Ate1	A	G	7: 130,105,570 (GRCm39)	V316A	probably damaging	Het
Bpifa1	A	G	2: 153,986,180 (GRCm39)	I102V	probably benign	Het
Catsperb	A	G	12: 101,557,655 (GRCm39)		probably null	Het
Ccdc47	T	C	11: 106,094,427 (GRCm39)	Y324C	probably damaging	Het
Cdh22	T	C	2: 164,985,564 (GRCm39)	K341E	possibly damaging	Het
Cenpb	A	G	2: 131,020,289 (GRCm39)		probably benign	Het
Dgkd	A	G	1: 87,853,866 (GRCm39)	I570V	possibly damaging	Het
Dhx32	A	T	7: 133,344,529 (GRCm39)	Y27N	probably damaging	Het
Fbxo8	T	A	8: 57,022,323 (GRCm39)	C112S	probably damaging	Het
Fndc3a	T	C	14: 72,800,980 (GRCm39)	D590G	probably damaging	Het
Gm19965	T	A	1: 116,750,410 (GRCm39)	I697N	possibly damaging	Het
Greb1l	G	A	18: 10,469,494 (GRCm39)	D170N	probably damaging	Het
Haus5	C	T	7: 30,358,401 (GRCm39)	W298*	probably null	Het
Igfn1	A	T	1: 135,892,399 (GRCm39)		probably null	Het
Ighg2b	T	C	12: 113,270,512 (GRCm39)	E206G	unknown	Het
Ints15	A	T	5: 143,293,787 (GRCm39)	L230Q	possibly damaging	Het
Lman2	T	C	13: 55,496,244 (GRCm39)	N267S	probably damaging	Het
Lrfn5	A	T	12: 61,890,348 (GRCm39)	I546F	probably benign	Het
Lrrc4c	T	C	2: 97,459,964 (GRCm39)	S197P	probably damaging	Het
Mbtd1	C	T	11: 93,823,058 (GRCm39)	H493Y	possibly damaging	Het
Mdga2	A	G	12: 66,553,027 (GRCm39)	Y793H	probably damaging	Het
Mdn1	C	T	4: 32,730,054 (GRCm39)	R2799*	probably null	Het
Mup13	T	A	4: 61,181,634 (GRCm39)	I148F	probably benign	Het
Or2aj5	A	C	16: 19,424,680 (GRCm39)	V246G	possibly damaging	Het
Or5m10	A	G	2: 85,717,159 (GRCm39)	N5S	probably benign	Het
Or8g53	A	T	9: 39,683,522 (GRCm39)	D191E	possibly damaging	Het
Pdgfra	A	G	5: 75,334,135 (GRCm39)	K403E	possibly damaging	Het
Pigz	A	T	16: 31,763,755 (GRCm39)	Y271F	probably damaging	Het
Plekhg4	T	C	8: 106,104,472 (GRCm39)	L517P	probably damaging	Het
Rnf20	T	C	4: 49,642,132 (GRCm39)	L232P	probably damaging	Het
Rpa3	C	A	6: 8,256,767 (GRCm39)	G71*	probably null	Het
Rsf1	GCG	GCGACGGCGTCG	7: 97,229,114 (GRCm39)		probably benign	Het
Rubcnl	A	G	14: 75,287,584 (GRCm39)	T623A	probably benign	Het
Sltm	A	G	9: 70,488,641 (GRCm39)	D597G	probably damaging	Het
Stpg2	T	C	3: 139,407,432 (GRCm39)	V528A	possibly damaging	Het
Supt6	C	T	11: 78,116,885 (GRCm39)	R589Q	possibly damaging	Het
Tas1r2	T	A	4: 139,389,361 (GRCm39)	M419K	possibly damaging	Het
Txndc16	T	C	14: 45,389,243 (GRCm39)	T486A	probably benign	Het
Vamp9	A	G	5: 100,089,092 (GRCm39)	Y119C	probably damaging	Het
Vmn1r185	A	G	7: 26,311,046 (GRCm39)	V153A	probably benign	Het
Vmn2r48	T	C	7: 9,668,807 (GRCm39)	N548D	probably damaging	Het
Washc5	A	G	15: 59,215,895 (GRCm39)	I378T	possibly damaging	Het
Wdr37	A	G	13: 8,892,764 (GRCm39)		probably null	Het
Xrn2	G	A	2: 146,868,490 (GRCm39)	R181H	probably damaging	Het
Ylpm1	C	G	12: 85,062,051 (GRCm39)	P651A	unknown	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,905,667 (GRCm39)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,823,680 (GRCm39)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,871,405 (GRCm39)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,852,576 (GRCm39)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,854,276 (GRCm39)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,856,218 (GRCm39)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,861,010 (GRCm39)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,898,405 (GRCm39)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,809,553 (GRCm39)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,880,392 (GRCm39)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,864,529 (GRCm39)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,845,991 (GRCm39)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,832,850 (GRCm39)	missense	probably benign
IGL01767:Dnah10	APN	5	124,820,801 (GRCm39)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,842,008 (GRCm39)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,860,985 (GRCm39)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,866,876 (GRCm39)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,881,810 (GRCm39)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,896,430 (GRCm39)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,910,487 (GRCm39)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,850,131 (GRCm39)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,850,883 (GRCm39)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,870,916 (GRCm39)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,898,351 (GRCm39)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,864,395 (GRCm39)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,876,069 (GRCm39)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,850,809 (GRCm39)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,903,927 (GRCm39)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,807,150 (GRCm39)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,875,078 (GRCm39)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,878,886 (GRCm39)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,840,197 (GRCm39)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,807,226 (GRCm39)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,841,950 (GRCm39)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,825,521 (GRCm39)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,894,707 (GRCm39)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,894,761 (GRCm39)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,831,354 (GRCm39)	missense	probably benign	0.06
frosty	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,906,593 (GRCm39)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,807,164 (GRCm39)	missense	probably benign
P0019:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
P0037:Dnah10	UTSW	5	124,895,056 (GRCm39)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,852,588 (GRCm39)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,803,966 (GRCm39)	missense	probably benign
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,907,808 (GRCm39)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,840,140 (GRCm39)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,911,139 (GRCm39)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,873,433 (GRCm39)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,900,416 (GRCm39)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,832,799 (GRCm39)	missense	probably benign
R0480:Dnah10	UTSW	5	124,885,915 (GRCm39)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,889,787 (GRCm39)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,852,314 (GRCm39)	splice site	probably null
R0599:Dnah10	UTSW	5	124,878,017 (GRCm39)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,827,876 (GRCm39)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,906,641 (GRCm39)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,875,002 (GRCm39)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,837,078 (GRCm39)	splice site	probably null
R1248:Dnah10	UTSW	5	124,832,887 (GRCm39)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,830,390 (GRCm39)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,852,050 (GRCm39)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,839,285 (GRCm39)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,876,009 (GRCm39)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,820,750 (GRCm39)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1479:Dnah10	UTSW	5	124,854,953 (GRCm39)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,831,303 (GRCm39)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,838,016 (GRCm39)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,906,678 (GRCm39)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,842,626 (GRCm39)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,837,155 (GRCm39)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,850,254 (GRCm39)	splice site	probably null
R1828:Dnah10	UTSW	5	124,838,343 (GRCm39)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,881,753 (GRCm39)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,909,590 (GRCm39)	splice site	probably null
R1893:Dnah10	UTSW	5	124,831,381 (GRCm39)	missense	probably benign	0.13
R1895:Dnah10	UTSW	5	124,835,494 (GRCm39)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,878,048 (GRCm39)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,859,332 (GRCm39)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,852,267 (GRCm39)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,911,052 (GRCm39)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,906,651 (GRCm39)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,823,768 (GRCm39)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,873,405 (GRCm39)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,891,738 (GRCm39)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,852,045 (GRCm39)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,838,301 (GRCm39)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,808,530 (GRCm39)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,896,285 (GRCm39)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,819,064 (GRCm39)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,839,929 (GRCm39)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,852,542 (GRCm39)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,894,734 (GRCm39)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,896,476 (GRCm39)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,873,322 (GRCm39)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,824,694 (GRCm39)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,850,095 (GRCm39)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,854,990 (GRCm39)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,807,201 (GRCm39)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,809,394 (GRCm39)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,896,989 (GRCm39)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,839,933 (GRCm39)	splice site	probably null
R4651:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,852,581 (GRCm39)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,824,809 (GRCm39)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,896,408 (GRCm39)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,850,196 (GRCm39)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,894,812 (GRCm39)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,839,260 (GRCm39)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,909,577 (GRCm39)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,856,322 (GRCm39)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,876,024 (GRCm39)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,864,484 (GRCm39)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,862,220 (GRCm39)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,868,851 (GRCm39)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,850,630 (GRCm39)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,820,693 (GRCm39)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,907,557 (GRCm39)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,830,232 (GRCm39)	missense	probably benign
R5587:Dnah10	UTSW	5	124,870,977 (GRCm39)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,819,090 (GRCm39)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,898,450 (GRCm39)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,824,810 (GRCm39)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,900,437 (GRCm39)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,885,793 (GRCm39)	missense	probably benign
R6021:Dnah10	UTSW	5	124,814,048 (GRCm39)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,878,924 (GRCm39)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,896,274 (GRCm39)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,882,961 (GRCm39)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,830,238 (GRCm39)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,862,239 (GRCm39)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,847,663 (GRCm39)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,900,382 (GRCm39)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,820,743 (GRCm39)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,871,283 (GRCm39)	splice site	probably null
R6275:Dnah10	UTSW	5	124,862,248 (GRCm39)	missense	probably damaging	1.00
R6388:Dnah10	UTSW	5	124,906,710 (GRCm39)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,886,333 (GRCm39)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,839,846 (GRCm39)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,835,419 (GRCm39)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,907,097 (GRCm39)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,837,223 (GRCm39)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,882,869 (GRCm39)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,885,876 (GRCm39)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,854,890 (GRCm39)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,867,064 (GRCm39)	splice site	probably null
R6932:Dnah10	UTSW	5	124,898,514 (GRCm39)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,864,490 (GRCm39)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,893,206 (GRCm39)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,900,009 (GRCm39)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,900,006 (GRCm39)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,890,892 (GRCm39)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,909,662 (GRCm39)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,898,333 (GRCm39)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,824,803 (GRCm39)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,876,095 (GRCm39)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,823,608 (GRCm39)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,894,776 (GRCm39)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,854,298 (GRCm39)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,859,425 (GRCm39)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,803,949 (GRCm39)	missense	probably benign
R7999:Dnah10	UTSW	5	124,802,322 (GRCm39)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,877,949 (GRCm39)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,823,676 (GRCm39)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,905,575 (GRCm39)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,831,330 (GRCm39)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,877,946 (GRCm39)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,832,790 (GRCm39)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,905,524 (GRCm39)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,827,858 (GRCm39)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,859,410 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,909,566 (GRCm39)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,850,606 (GRCm39)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,813,895 (GRCm39)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,893,164 (GRCm39)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,803,911 (GRCm39)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,891,685 (GRCm39)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,852,410 (GRCm39)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,842,614 (GRCm39)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,895,181 (GRCm39)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,866,828 (GRCm39)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,878,015 (GRCm39)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,891,006 (GRCm39)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,814,057 (GRCm39)	missense
R9001:Dnah10	UTSW	5	124,852,515 (GRCm39)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,820,783 (GRCm39)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,905,141 (GRCm39)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,839,237 (GRCm39)	missense
R9133:Dnah10	UTSW	5	124,859,423 (GRCm39)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,907,475 (GRCm39)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,871,437 (GRCm39)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,818,989 (GRCm39)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,813,900 (GRCm39)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,845,990 (GRCm39)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,871,507 (GRCm39)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,823,677 (GRCm39)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,900,508 (GRCm39)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,907,107 (GRCm39)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,852,249 (GRCm39)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,895,141 (GRCm39)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,854,971 (GRCm39)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
U24488:Dnah10	UTSW	5	124,891,044 (GRCm39)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,842,761 (GRCm39)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,852,419 (GRCm39)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,819,019 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,895,052 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,824,683 (GRCm39)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- AGCCCTGGAGTTTTCTTGGC -3'
(R):5'- TGAAGCAATCCCAGTGTCC -3'

Sequencing Primer
(F):5'- TGTTCCTGGCCAGACATGC -3'
(R):5'- AATCCCAGTGTCCCAGGGATG -3'

Posted On

2018-04-02