Incidental Mutation 'R0612:Parp14'
| ID |
54845 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Parp14
|
| Ensembl Gene |
ENSMUSG00000034422 |
| Gene Name |
poly (ADP-ribose) polymerase family, member 14 |
| Synonyms |
CoaSt6, collaborator of Stat6, 1600029O10Rik |
| MMRRC Submission |
038801-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.493)
|
| Stock # |
R0612 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
35653244-35691914 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 35677130 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Valine
at position 946
(A946V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037657
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042665]
|
| AlphaFold |
Q2EMV9 |
| PDB Structure |
Solution structure of WWE domain in Parp14 protein [SOLUTION NMR]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000042665
AA Change: A946V
PolyPhen 2
Score 0.089 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000037657
Gene: ENSMUSG00000034422
AA Change: A946V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
38 |
49 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
115 |
N/A |
INTRINSIC |
|
RRM
|
228 |
297 |
4.71e-2 |
SMART |
|
coiled coil region
|
443 |
468 |
N/A |
INTRINSIC |
|
Blast:A1pp
|
693 |
746 |
6e-6 |
BLAST |
|
low complexity region
|
771 |
795 |
N/A |
INTRINSIC |
|
A1pp
|
814 |
948 |
7.62e-41 |
SMART |
|
A1pp
|
1026 |
1160 |
5.88e-24 |
SMART |
|
A1pp
|
1239 |
1358 |
6.82e-20 |
SMART |
|
PDB:1X4R|A
|
1532 |
1619 |
9e-53 |
PDB |
|
Pfam:PARP
|
1632 |
1817 |
2.5e-29 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142946
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.6%
- 3x: 99.0%
- 10x: 97.2%
- 20x: 93.5%
|
| Validation Efficiency |
98% (92/94) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the poly(ADP-ribose) polymerase (PARP) protein family. The encoded anti-apoptotic protein may regulate aerobic glycolysis and promote survival of cancer cells. Increased expression of this gene has been reported in a variety of tumor types. [provided by RefSeq, Jul 2016]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit altered B cell subsets and inability to respond to the apoptosis protective affects of IL4. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca15 |
T |
C |
7: 119,936,478 (GRCm39) |
L181P |
probably damaging |
Het |
| Aldh3a1 |
A |
T |
11: 61,105,445 (GRCm39) |
I184F |
probably damaging |
Het |
| Arl6ip4 |
A |
G |
5: 124,254,596 (GRCm39) |
S30G |
probably benign |
Het |
| Atp9b |
T |
C |
18: 80,797,171 (GRCm39) |
E891G |
possibly damaging |
Het |
| Brsk1 |
T |
C |
7: 4,710,425 (GRCm39) |
L478P |
possibly damaging |
Het |
| Btaf1 |
G |
A |
19: 36,946,537 (GRCm39) |
V448I |
probably damaging |
Het |
| Cab39 |
T |
C |
1: 85,746,236 (GRCm39) |
|
probably null |
Het |
| Cacna2d4 |
G |
T |
6: 119,258,679 (GRCm39) |
|
probably benign |
Het |
| Capzb |
C |
T |
4: 139,018,340 (GRCm39) |
S253L |
probably benign |
Het |
| Ccdc174 |
A |
G |
6: 91,867,873 (GRCm39) |
|
probably benign |
Het |
| Ccdc180 |
C |
T |
4: 45,927,969 (GRCm39) |
A1168V |
probably damaging |
Het |
| Cdh19 |
T |
C |
1: 110,820,900 (GRCm39) |
|
probably benign |
Het |
| Cdh8 |
T |
C |
8: 100,127,546 (GRCm39) |
T22A |
probably benign |
Het |
| Cdk10 |
T |
C |
8: 123,957,419 (GRCm39) |
V181A |
probably benign |
Het |
| Ceacam15 |
A |
C |
7: 16,407,445 (GRCm39) |
L24* |
probably null |
Het |
| Cftr |
A |
C |
6: 18,198,125 (GRCm39) |
T20P |
probably benign |
Het |
| Cip2a |
C |
T |
16: 48,819,402 (GRCm39) |
A112V |
probably benign |
Het |
| Clstn3 |
T |
C |
6: 124,426,459 (GRCm39) |
T576A |
probably damaging |
Het |
| Col1a2 |
G |
A |
6: 4,516,003 (GRCm39) |
V165I |
unknown |
Het |
| Copg2 |
A |
T |
6: 30,838,404 (GRCm39) |
|
probably null |
Het |
| Cps1 |
A |
G |
1: 67,178,929 (GRCm39) |
H47R |
probably benign |
Het |
| Cytip |
T |
C |
2: 58,024,202 (GRCm39) |
D206G |
possibly damaging |
Het |
| Dcaf8l |
G |
A |
X: 88,448,972 (GRCm39) |
R386* |
probably null |
Het |
| Dnmt1 |
C |
T |
9: 20,829,489 (GRCm39) |
E824K |
probably damaging |
Het |
| Dock7 |
A |
C |
4: 98,877,470 (GRCm39) |
V442G |
probably benign |
Het |
| Dsc1 |
T |
G |
18: 20,247,573 (GRCm39) |
K14T |
probably damaging |
Het |
| Dync1h1 |
C |
T |
12: 110,582,930 (GRCm39) |
P371L |
probably damaging |
Het |
| Enah |
A |
G |
1: 181,734,013 (GRCm39) |
|
probably benign |
Het |
| Entrep2 |
C |
T |
7: 64,411,549 (GRCm39) |
V395M |
probably benign |
Het |
| Fastkd1 |
T |
C |
2: 69,542,727 (GRCm39) |
T27A |
probably benign |
Het |
| Fcho1 |
A |
G |
8: 72,168,168 (GRCm39) |
L248P |
probably damaging |
Het |
| Fezf1 |
A |
T |
6: 23,247,028 (GRCm39) |
V268D |
probably damaging |
Het |
| Fgd2 |
T |
A |
17: 29,597,321 (GRCm39) |
V547E |
probably benign |
Het |
| Flnb |
T |
A |
14: 7,887,682 (GRCm38) |
|
probably benign |
Het |
| Gabrg3 |
A |
G |
7: 56,379,454 (GRCm39) |
M316T |
probably damaging |
Het |
| Gigyf2 |
T |
C |
1: 87,376,802 (GRCm39) |
F1265L |
probably damaging |
Het |
| Git2 |
A |
G |
5: 114,890,342 (GRCm39) |
S271P |
probably damaging |
Het |
| Gorab |
T |
C |
1: 163,224,738 (GRCm39) |
D21G |
possibly damaging |
Het |
| Gpr179 |
T |
A |
11: 97,229,264 (GRCm39) |
T964S |
possibly damaging |
Het |
| Hdac5 |
A |
G |
11: 102,087,078 (GRCm39) |
V1042A |
possibly damaging |
Het |
| Hoxa2 |
T |
A |
6: 52,140,540 (GRCm39) |
T149S |
probably damaging |
Het |
| Igsf8 |
G |
T |
1: 172,146,974 (GRCm39) |
*108L |
probably null |
Het |
| Il1rap |
C |
T |
16: 26,519,855 (GRCm39) |
T307M |
possibly damaging |
Het |
| Itih2 |
T |
C |
2: 10,122,205 (GRCm39) |
D232G |
probably benign |
Het |
| Jak3 |
A |
G |
8: 72,136,021 (GRCm39) |
Y607C |
probably damaging |
Het |
| Kcnh1 |
C |
T |
1: 191,959,361 (GRCm39) |
P305L |
probably damaging |
Het |
| Lrrc7 |
T |
A |
3: 157,869,990 (GRCm39) |
I644F |
probably damaging |
Het |
| Lrrn2 |
T |
C |
1: 132,865,466 (GRCm39) |
L177P |
probably damaging |
Het |
| Lypd8l |
A |
G |
11: 58,502,799 (GRCm39) |
|
probably null |
Het |
| Map4k3 |
C |
A |
17: 80,909,622 (GRCm39) |
K712N |
probably damaging |
Het |
| Med11 |
A |
G |
11: 70,342,910 (GRCm39) |
T36A |
probably benign |
Het |
| Mmp14 |
A |
G |
14: 54,677,891 (GRCm39) |
D504G |
probably damaging |
Het |
| Mob1a |
A |
G |
6: 83,311,140 (GRCm39) |
T120A |
probably benign |
Het |
| Mr1 |
T |
A |
1: 155,013,436 (GRCm39) |
D47V |
probably damaging |
Het |
| Nacad |
G |
T |
11: 6,551,382 (GRCm39) |
A603E |
possibly damaging |
Het |
| Nwd1 |
T |
A |
8: 73,394,308 (GRCm39) |
W524R |
probably damaging |
Het |
| Or11g26 |
A |
T |
14: 50,752,939 (GRCm39) |
T93S |
probably benign |
Het |
| Or13a19 |
T |
A |
7: 139,903,101 (GRCm39) |
M163K |
possibly damaging |
Het |
| Or4e1 |
T |
C |
14: 52,701,008 (GRCm39) |
T153A |
probably benign |
Het |
| Pde6c |
T |
A |
19: 38,121,694 (GRCm39) |
C101S |
probably benign |
Het |
| Pdia3 |
G |
A |
2: 121,262,858 (GRCm39) |
G275S |
probably damaging |
Het |
| Pdlim4 |
G |
A |
11: 53,959,713 (GRCm39) |
R16C |
probably damaging |
Het |
| Pfkp |
A |
G |
13: 6,655,670 (GRCm39) |
|
probably null |
Het |
| Plcg2 |
T |
A |
8: 118,300,104 (GRCm39) |
S225T |
probably benign |
Het |
| Pramel1 |
T |
C |
4: 143,124,101 (GRCm39) |
S259P |
probably damaging |
Het |
| Pramel27 |
G |
T |
4: 143,578,658 (GRCm39) |
|
probably benign |
Het |
| Rc3h2 |
T |
C |
2: 37,301,227 (GRCm39) |
N92D |
possibly damaging |
Het |
| Ric8b |
C |
A |
10: 84,837,745 (GRCm39) |
N517K |
probably damaging |
Het |
| Rnf34 |
G |
A |
5: 123,002,237 (GRCm39) |
R65H |
probably damaging |
Het |
| Rraga |
C |
T |
4: 86,494,564 (GRCm39) |
R137C |
probably damaging |
Het |
| Scube2 |
C |
T |
7: 109,403,971 (GRCm39) |
|
probably benign |
Het |
| Slc28a2b |
T |
C |
2: 122,352,179 (GRCm39) |
M339T |
probably damaging |
Het |
| Spata31d1d |
T |
C |
13: 59,875,787 (GRCm39) |
I583V |
probably benign |
Het |
| Suox |
T |
C |
10: 128,506,525 (GRCm39) |
E501G |
probably benign |
Het |
| Susd1 |
A |
G |
4: 59,390,561 (GRCm39) |
|
probably benign |
Het |
| Tac1 |
T |
C |
6: 7,555,653 (GRCm39) |
S14P |
probably damaging |
Het |
| Tbc1d8 |
T |
C |
1: 39,411,596 (GRCm39) |
E1080G |
possibly damaging |
Het |
| Tll1 |
A |
C |
8: 64,524,344 (GRCm39) |
S447R |
possibly damaging |
Het |
| Tmem132e |
G |
A |
11: 82,334,198 (GRCm39) |
V662M |
probably damaging |
Het |
| Upf2 |
G |
T |
2: 6,038,909 (GRCm39) |
|
probably benign |
Het |
| Uspl1 |
A |
G |
5: 149,151,767 (GRCm39) |
E989G |
probably damaging |
Het |
| Vmn1r58 |
T |
C |
7: 5,413,618 (GRCm39) |
H204R |
probably damaging |
Het |
| Vmn2r25 |
A |
T |
6: 123,816,481 (GRCm39) |
C367S |
probably damaging |
Het |
| Vps13b |
A |
T |
15: 35,623,803 (GRCm39) |
Q1240L |
probably benign |
Het |
| Xrcc1 |
C |
T |
7: 24,269,744 (GRCm39) |
|
probably benign |
Het |
| Yeats2 |
T |
G |
16: 20,005,175 (GRCm39) |
V385G |
probably benign |
Het |
|
| Other mutations in Parp14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Parp14
|
APN |
16 |
35,661,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00497:Parp14
|
APN |
16 |
35,655,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00754:Parp14
|
APN |
16 |
35,659,741 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL00960:Parp14
|
APN |
16 |
35,661,589 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL01321:Parp14
|
APN |
16 |
35,676,929 (GRCm39) |
missense |
probably benign |
|
|
IGL01397:Parp14
|
APN |
16 |
35,679,098 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01591:Parp14
|
APN |
16 |
35,678,877 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01728:Parp14
|
APN |
16 |
35,677,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01734:Parp14
|
APN |
16 |
35,678,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02156:Parp14
|
APN |
16 |
35,678,967 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02951:Parp14
|
APN |
16 |
35,678,903 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03067:Parp14
|
APN |
16 |
35,676,878 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL03135:Parp14
|
APN |
16 |
35,678,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03141:Parp14
|
APN |
16 |
35,659,663 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03146:Parp14
|
APN |
16 |
35,678,823 (GRCm39) |
nonsense |
probably null |
|
|
IGL03333:Parp14
|
APN |
16 |
35,661,800 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03391:Parp14
|
APN |
16 |
35,678,640 (GRCm39) |
missense |
probably benign |
|
|
thurston
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
PIT4585001:Parp14
|
UTSW |
16 |
35,678,975 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0306:Parp14
|
UTSW |
16 |
35,676,944 (GRCm39) |
missense |
probably benign |
|
|
R0506:Parp14
|
UTSW |
16 |
35,661,779 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R0586:Parp14
|
UTSW |
16 |
35,661,382 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0606:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0699:Parp14
|
UTSW |
16 |
35,680,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0786:Parp14
|
UTSW |
16 |
35,661,172 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0883:Parp14
|
UTSW |
16 |
35,678,888 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0900:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1087:Parp14
|
UTSW |
16 |
35,678,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Parp14
|
UTSW |
16 |
35,664,785 (GRCm39) |
splice site |
probably benign |
|
|
R1120:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1134:Parp14
|
UTSW |
16 |
35,655,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1153:Parp14
|
UTSW |
16 |
35,678,041 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1159:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1160:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1237:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1238:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1239:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1423:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1511:Parp14
|
UTSW |
16 |
35,677,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1518:Parp14
|
UTSW |
16 |
35,677,008 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1619:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1707:Parp14
|
UTSW |
16 |
35,678,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1792:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1831:Parp14
|
UTSW |
16 |
35,678,958 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1840:Parp14
|
UTSW |
16 |
35,683,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Parp14
|
UTSW |
16 |
35,677,130 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1902:Parp14
|
UTSW |
16 |
35,673,888 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1943:Parp14
|
UTSW |
16 |
35,656,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Parp14
|
UTSW |
16 |
35,678,671 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2115:Parp14
|
UTSW |
16 |
35,678,904 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2216:Parp14
|
UTSW |
16 |
35,677,575 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2519:Parp14
|
UTSW |
16 |
35,678,573 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3851:Parp14
|
UTSW |
16 |
35,674,118 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4052:Parp14
|
UTSW |
16 |
35,678,771 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4671:Parp14
|
UTSW |
16 |
35,678,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4867:Parp14
|
UTSW |
16 |
35,677,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4941:Parp14
|
UTSW |
16 |
35,666,403 (GRCm39) |
missense |
probably benign |
|
|
R4992:Parp14
|
UTSW |
16 |
35,661,512 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5055:Parp14
|
UTSW |
16 |
35,664,733 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5073:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5170:Parp14
|
UTSW |
16 |
35,677,649 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5422:Parp14
|
UTSW |
16 |
35,686,545 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5543:Parp14
|
UTSW |
16 |
35,655,137 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5549:Parp14
|
UTSW |
16 |
35,661,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5553:Parp14
|
UTSW |
16 |
35,677,306 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5691:Parp14
|
UTSW |
16 |
35,683,909 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5774:Parp14
|
UTSW |
16 |
35,678,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5855:Parp14
|
UTSW |
16 |
35,661,297 (GRCm39) |
nonsense |
probably null |
|
|
R5942:Parp14
|
UTSW |
16 |
35,659,737 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5990:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5991:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6018:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6022:Parp14
|
UTSW |
16 |
35,661,827 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6075:Parp14
|
UTSW |
16 |
35,677,389 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6395:Parp14
|
UTSW |
16 |
35,676,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6525:Parp14
|
UTSW |
16 |
35,680,811 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6683:Parp14
|
UTSW |
16 |
35,655,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7525:Parp14
|
UTSW |
16 |
35,677,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8011:Parp14
|
UTSW |
16 |
35,677,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8192:Parp14
|
UTSW |
16 |
35,691,584 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8367:Parp14
|
UTSW |
16 |
35,678,124 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8526:Parp14
|
UTSW |
16 |
35,661,307 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8751:Parp14
|
UTSW |
16 |
35,677,181 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8962:Parp14
|
UTSW |
16 |
35,677,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Parp14
|
UTSW |
16 |
35,661,583 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9363:Parp14
|
UTSW |
16 |
35,678,586 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9366:Parp14
|
UTSW |
16 |
35,659,630 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9379:Parp14
|
UTSW |
16 |
35,680,853 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9562:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9565:Parp14
|
UTSW |
16 |
35,677,775 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,252 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9696:Parp14
|
UTSW |
16 |
35,661,251 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0026:Parp14
|
UTSW |
16 |
35,677,527 (GRCm39) |
nonsense |
probably null |
|
|
X0060:Parp14
|
UTSW |
16 |
35,655,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Parp14
|
UTSW |
16 |
35,661,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,665,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Parp14
|
UTSW |
16 |
35,691,573 (GRCm39) |
missense |
probably benign |
0.16 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTACCGTAGCATTCTGCACGCC -3'
(R):5'- AAGCATATCAGCGGTCTCGCAC -3'
Sequencing Primer
(F):5'- TCTACCAGGCGGATTCTCAG -3'
(R):5'- GCTGTTATCTCAAAAGCAGGC -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation