Incidental Mutation 'R1773:Zfhx2'
| ID |
196855 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfhx2
|
| Ensembl Gene |
ENSMUSG00000040721 |
| Gene Name |
zinc finger homeobox 2 |
| Synonyms |
zfh-5 |
| MMRRC Submission |
039804-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.354)
|
| Stock # |
R1773 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
55297719-55329781 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 55310348 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Glycine
at position 733
(C733G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045156
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036328]
[ENSMUST00000183822]
[ENSMUST00000185121]
|
| AlphaFold |
Q2MHN3 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000036328
AA Change: C733G
PolyPhen 2
Score 0.533 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000045156
Gene: ENSMUSG00000040721
AA Change: C733G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
22 |
42 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
230 |
252 |
1.43e1 |
SMART |
|
low complexity region
|
333 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
428 |
439 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
446 |
469 |
8.94e-3 |
SMART |
|
ZnF_U1
|
498 |
532 |
6.98e-1 |
SMART |
|
ZnF_C2H2
|
501 |
525 |
3.21e-4 |
SMART |
|
ZnF_U1
|
560 |
594 |
1.36e0 |
SMART |
|
ZnF_C2H2
|
563 |
587 |
3.29e-1 |
SMART |
|
low complexity region
|
597 |
623 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
752 |
776 |
6.4e0 |
SMART |
|
ZnF_C2H2
|
815 |
839 |
2.02e-1 |
SMART |
|
ZnF_U1
|
861 |
895 |
1.78e1 |
SMART |
|
ZnF_C2H2
|
864 |
888 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
974 |
997 |
1.51e1 |
SMART |
|
ZnF_C2H2
|
1003 |
1026 |
1.51e0 |
SMART |
|
low complexity region
|
1087 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1106 |
1126 |
N/A |
INTRINSIC |
|
ZnF_U1
|
1182 |
1216 |
3.42e0 |
SMART |
|
ZnF_C2H2
|
1185 |
1209 |
8.22e-2 |
SMART |
|
ZnF_U1
|
1239 |
1273 |
3.73e0 |
SMART |
|
ZnF_C2H2
|
1242 |
1266 |
6.67e-2 |
SMART |
|
low complexity region
|
1277 |
1304 |
N/A |
INTRINSIC |
|
low complexity region
|
1314 |
1326 |
N/A |
INTRINSIC |
|
low complexity region
|
1332 |
1346 |
N/A |
INTRINSIC |
|
low complexity region
|
1349 |
1359 |
N/A |
INTRINSIC |
|
low complexity region
|
1379 |
1400 |
N/A |
INTRINSIC |
|
low complexity region
|
1457 |
1465 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1474 |
1497 |
5.34e0 |
SMART |
|
low complexity region
|
1522 |
1531 |
N/A |
INTRINSIC |
|
low complexity region
|
1542 |
1554 |
N/A |
INTRINSIC |
|
low complexity region
|
1562 |
1583 |
N/A |
INTRINSIC |
|
HOX
|
1589 |
1651 |
1.97e-16 |
SMART |
|
low complexity region
|
1656 |
1665 |
N/A |
INTRINSIC |
|
coiled coil region
|
1693 |
1723 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1761 |
1783 |
2.53e-2 |
SMART |
|
low complexity region
|
1837 |
1847 |
N/A |
INTRINSIC |
|
HOX
|
1851 |
1913 |
2.34e-18 |
SMART |
|
low complexity region
|
1984 |
1995 |
N/A |
INTRINSIC |
|
low complexity region
|
2001 |
2051 |
N/A |
INTRINSIC |
|
HOX
|
2058 |
2120 |
1.52e-17 |
SMART |
|
ZnF_U1
|
2136 |
2170 |
1.09e1 |
SMART |
|
ZnF_C2H2
|
2139 |
2163 |
5.4e1 |
SMART |
|
low complexity region
|
2328 |
2354 |
N/A |
INTRINSIC |
|
low complexity region
|
2385 |
2426 |
N/A |
INTRINSIC |
|
ZnF_U1
|
2482 |
2516 |
8.31e-1 |
SMART |
|
ZnF_C2H2
|
2485 |
2509 |
9.46e0 |
SMART |
|
low complexity region
|
2523 |
2538 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2562 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176665
|
| SMART Domains |
Protein: ENSMUSP00000134955
Gene: ENSMUSG00000040721
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
13 |
37 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
133 |
156 |
1.51e1 |
SMART |
|
ZnF_C2H2
|
162 |
185 |
1.51e0 |
SMART |
|
low complexity region
|
246 |
262 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
285 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
344 |
368 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
401 |
425 |
6.67e-2 |
SMART |
|
low complexity region
|
436 |
463 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
485 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
505 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
518 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
559 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176872
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183750
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183822
|
| SMART Domains |
Protein: ENSMUSP00000140371
Gene: ENSMUSG00000045691
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:2JMU|A
|
5 |
64 |
3e-23 |
PDB |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183993
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185121
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000185430
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
A |
G |
7: 27,280,020 (GRCm39) |
K334E |
probably damaging |
Het |
| Abca12 |
A |
G |
1: 71,327,755 (GRCm39) |
Y1442H |
probably damaging |
Het |
| Acot12 |
A |
G |
13: 91,905,676 (GRCm39) |
T79A |
probably benign |
Het |
| Adipoq |
A |
C |
16: 22,973,988 (GRCm39) |
Q26P |
unknown |
Het |
| Afg2a |
T |
C |
3: 37,493,334 (GRCm39) |
F515L |
probably damaging |
Het |
| Akap13 |
T |
A |
7: 75,333,199 (GRCm39) |
N1582K |
possibly damaging |
Het |
| Alg9 |
A |
G |
9: 50,690,396 (GRCm39) |
T133A |
probably benign |
Het |
| Anks3 |
T |
C |
16: 4,765,158 (GRCm39) |
T418A |
probably benign |
Het |
| Ano3 |
A |
C |
2: 110,591,800 (GRCm39) |
L37R |
probably damaging |
Het |
| Ano9 |
A |
G |
7: 140,688,291 (GRCm39) |
F178L |
possibly damaging |
Het |
| Arhgef12 |
A |
G |
9: 42,916,838 (GRCm39) |
|
probably null |
Het |
| Arl16 |
T |
A |
11: 120,356,589 (GRCm39) |
I137F |
possibly damaging |
Het |
| Brpf1 |
T |
A |
6: 113,296,892 (GRCm39) |
S959T |
possibly damaging |
Het |
| Ccdc27 |
C |
T |
4: 154,126,222 (GRCm39) |
R89Q |
unknown |
Het |
| Cd109 |
A |
C |
9: 78,611,006 (GRCm39) |
Q1207H |
probably benign |
Het |
| Cd14 |
A |
T |
18: 36,858,357 (GRCm39) |
V366D |
possibly damaging |
Het |
| Cep290 |
G |
A |
10: 100,346,435 (GRCm39) |
V538I |
probably benign |
Het |
| Cep57 |
G |
A |
9: 13,727,364 (GRCm39) |
A202V |
probably damaging |
Het |
| Chl1 |
T |
C |
6: 103,624,292 (GRCm39) |
|
probably null |
Het |
| Cmah |
T |
G |
13: 24,601,282 (GRCm39) |
F29L |
probably benign |
Het |
| Cracd |
G |
T |
5: 77,015,052 (GRCm39) |
A42S |
possibly damaging |
Het |
| Crybg1 |
A |
G |
10: 43,868,544 (GRCm39) |
V1378A |
possibly damaging |
Het |
| Cryzl2 |
A |
G |
1: 157,298,292 (GRCm39) |
K227R |
probably benign |
Het |
| D130043K22Rik |
T |
G |
13: 25,066,585 (GRCm39) |
V794G |
possibly damaging |
Het |
| Ddx4 |
T |
A |
13: 112,736,436 (GRCm39) |
T645S |
probably benign |
Het |
| Dhcr7 |
C |
T |
7: 143,401,195 (GRCm39) |
R453C |
possibly damaging |
Het |
| Dhx8 |
T |
C |
11: 101,643,189 (GRCm39) |
Y754H |
possibly damaging |
Het |
| Dip2b |
T |
A |
15: 100,091,842 (GRCm39) |
D860E |
probably benign |
Het |
| Dnah7a |
T |
C |
1: 53,472,046 (GRCm39) |
|
probably null |
Het |
| Dst |
A |
G |
1: 34,330,980 (GRCm39) |
D6937G |
probably damaging |
Het |
| Dusp1 |
A |
G |
17: 26,726,081 (GRCm39) |
I204T |
probably damaging |
Het |
| Dync2h1 |
T |
A |
9: 7,128,256 (GRCm39) |
Q1859L |
probably damaging |
Het |
| E4f1 |
C |
A |
17: 24,665,558 (GRCm39) |
G328V |
probably damaging |
Het |
| Eml5 |
T |
C |
12: 98,765,098 (GRCm39) |
Y1617C |
probably damaging |
Het |
| Espn |
G |
T |
4: 152,212,686 (GRCm39) |
P622Q |
probably damaging |
Het |
| Fam184b |
G |
A |
5: 45,741,676 (GRCm39) |
P185L |
possibly damaging |
Het |
| Fn1 |
T |
A |
1: 71,676,542 (GRCm39) |
D563V |
probably damaging |
Het |
| Gad2 |
A |
G |
2: 22,580,219 (GRCm39) |
Y540C |
probably benign |
Het |
| Garin1b |
T |
C |
6: 29,334,152 (GRCm39) |
S335P |
possibly damaging |
Het |
| Gdf11 |
T |
C |
10: 128,727,163 (GRCm39) |
D131G |
probably damaging |
Het |
| Gm19965 |
T |
A |
1: 116,748,989 (GRCm39) |
Y223* |
probably null |
Het |
| H2-M10.6 |
A |
G |
17: 37,123,076 (GRCm39) |
K3R |
probably benign |
Het |
| Hid1 |
A |
G |
11: 115,239,336 (GRCm39) |
Y776H |
probably damaging |
Het |
| Hivep3 |
A |
T |
4: 119,956,034 (GRCm39) |
K1450I |
probably damaging |
Het |
| Icam5 |
T |
C |
9: 20,944,821 (GRCm39) |
L128P |
possibly damaging |
Het |
| Idnk |
T |
C |
13: 58,305,526 (GRCm39) |
V9A |
probably damaging |
Het |
| Il4ra |
A |
T |
7: 125,166,354 (GRCm39) |
T33S |
possibly damaging |
Het |
| Ino80 |
A |
G |
2: 119,248,890 (GRCm39) |
V990A |
probably benign |
Het |
| Krtap4-9 |
T |
C |
11: 99,676,396 (GRCm39) |
|
probably benign |
Het |
| Lrrk2 |
A |
G |
15: 91,664,184 (GRCm39) |
I1974V |
possibly damaging |
Het |
| Mcm3ap |
C |
T |
10: 76,306,994 (GRCm39) |
A369V |
probably benign |
Het |
| Nek6 |
A |
G |
2: 38,472,431 (GRCm39) |
M252V |
probably benign |
Het |
| Nfasc |
T |
A |
1: 132,538,577 (GRCm39) |
I443F |
probably damaging |
Het |
| Nme8 |
T |
G |
13: 19,881,206 (GRCm39) |
M1L |
probably damaging |
Het |
| Npnt |
T |
A |
3: 132,610,454 (GRCm39) |
Q423L |
possibly damaging |
Het |
| Nup133 |
A |
T |
8: 124,657,722 (GRCm39) |
C404* |
probably null |
Het |
| Or2b7 |
T |
C |
13: 21,739,982 (GRCm39) |
D70G |
probably damaging |
Het |
| Or4c124 |
A |
G |
2: 89,156,086 (GRCm39) |
V146A |
probably benign |
Het |
| Or4f14b |
A |
G |
2: 111,775,204 (GRCm39) |
V199A |
possibly damaging |
Het |
| Or56a4 |
T |
C |
7: 104,806,190 (GRCm39) |
E233G |
probably benign |
Het |
| Or5an1c |
T |
C |
19: 12,219,023 (GRCm39) |
M1V |
probably null |
Het |
| Or6c213 |
A |
G |
10: 129,574,312 (GRCm39) |
L158S |
probably damaging |
Het |
| Otog |
T |
A |
7: 45,937,583 (GRCm39) |
I1764N |
probably benign |
Het |
| Oxa1l |
A |
G |
14: 54,600,909 (GRCm39) |
I127M |
probably benign |
Het |
| P4hb |
C |
A |
11: 120,463,552 (GRCm39) |
V28F |
probably damaging |
Het |
| Pbld2 |
C |
T |
10: 62,890,150 (GRCm39) |
A186V |
probably benign |
Het |
| Pdzph1 |
G |
T |
17: 59,281,808 (GRCm39) |
T158K |
probably damaging |
Het |
| Pgm2 |
T |
A |
5: 64,265,194 (GRCm39) |
|
probably null |
Het |
| Phip |
A |
T |
9: 82,758,242 (GRCm39) |
S1484T |
probably benign |
Het |
| Pikfyve |
T |
C |
1: 65,231,430 (GRCm39) |
L100P |
probably damaging |
Het |
| Pikfyve |
T |
C |
1: 65,285,529 (GRCm39) |
S923P |
probably benign |
Het |
| Pla2g4e |
A |
G |
2: 120,075,202 (GRCm39) |
S63P |
probably benign |
Het |
| Plekhh2 |
A |
G |
17: 84,906,693 (GRCm39) |
E1176G |
probably damaging |
Het |
| Prlr |
T |
A |
15: 10,325,404 (GRCm39) |
Y192* |
probably null |
Het |
| Pten |
T |
A |
19: 32,775,472 (GRCm39) |
C71S |
probably damaging |
Het |
| Rbbp8nl |
A |
G |
2: 179,922,987 (GRCm39) |
L202P |
probably benign |
Het |
| Ripor2 |
T |
A |
13: 24,885,237 (GRCm39) |
S491T |
probably benign |
Het |
| Robo1 |
A |
T |
16: 72,801,399 (GRCm39) |
I1008F |
probably benign |
Het |
| Scg2 |
T |
C |
1: 79,413,352 (GRCm39) |
N417S |
probably benign |
Het |
| Scn8a |
A |
G |
15: 100,937,496 (GRCm39) |
I1581V |
probably damaging |
Het |
| Slc22a8 |
T |
A |
19: 8,571,593 (GRCm39) |
I108N |
probably damaging |
Het |
| Slc9a8 |
A |
T |
2: 167,313,385 (GRCm39) |
T416S |
possibly damaging |
Het |
| Spata32 |
T |
A |
11: 103,099,644 (GRCm39) |
E287V |
probably damaging |
Het |
| Tgfbrap1 |
C |
T |
1: 43,114,512 (GRCm39) |
G196D |
probably damaging |
Het |
| Tgm5 |
G |
T |
2: 120,908,131 (GRCm39) |
T15K |
possibly damaging |
Het |
| Tmc1 |
C |
T |
19: 20,803,865 (GRCm39) |
|
probably null |
Het |
| Tmem177 |
T |
C |
1: 119,838,306 (GRCm39) |
I124M |
possibly damaging |
Het |
| Trim30a |
A |
G |
7: 104,085,108 (GRCm39) |
F34S |
probably damaging |
Het |
| Tsn |
T |
C |
1: 118,232,969 (GRCm39) |
T112A |
probably benign |
Het |
| Tspyl5 |
T |
G |
15: 33,686,922 (GRCm39) |
N341T |
probably benign |
Het |
| Vmn2r108 |
C |
T |
17: 20,689,335 (GRCm39) |
C540Y |
probably damaging |
Het |
| Vrtn |
C |
T |
12: 84,696,998 (GRCm39) |
R583W |
probably damaging |
Het |
| Wnt1 |
T |
C |
15: 98,689,638 (GRCm39) |
S142P |
probably damaging |
Het |
| Wrn |
A |
T |
8: 33,833,589 (GRCm39) |
I108N |
probably damaging |
Het |
| Zfp219 |
T |
C |
14: 52,244,563 (GRCm39) |
T539A |
probably damaging |
Het |
| Zswim8 |
T |
A |
14: 20,761,598 (GRCm39) |
M177K |
probably damaging |
Het |
|
| Other mutations in Zfhx2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00091:Zfhx2
|
APN |
14 |
55,304,022 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00164:Zfhx2
|
APN |
14 |
55,302,483 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL00235:Zfhx2
|
APN |
14 |
55,300,714 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL00925:Zfhx2
|
APN |
14 |
55,310,518 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01025:Zfhx2
|
APN |
14 |
55,301,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01061:Zfhx2
|
APN |
14 |
55,311,339 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL01486:Zfhx2
|
APN |
14 |
55,304,547 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Zfhx2
|
APN |
14 |
55,301,372 (GRCm39) |
missense |
unknown |
|
|
IGL01990:Zfhx2
|
APN |
14 |
55,311,047 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02097:Zfhx2
|
APN |
14 |
55,300,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02269:Zfhx2
|
APN |
14 |
55,309,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Zfhx2
|
APN |
14 |
55,302,560 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL02624:Zfhx2
|
APN |
14 |
55,304,085 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03087:Zfhx2
|
APN |
14 |
55,310,302 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
G1patch:Zfhx2
|
UTSW |
14 |
55,301,539 (GRCm39) |
nonsense |
probably null |
|
|
PIT4403001:Zfhx2
|
UTSW |
14 |
55,312,437 (GRCm39) |
missense |
probably benign |
|
|
R0148:Zfhx2
|
UTSW |
14 |
55,310,354 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0323:Zfhx2
|
UTSW |
14 |
55,303,436 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0328:Zfhx2
|
UTSW |
14 |
55,309,445 (GRCm39) |
missense |
probably benign |
|
|
R0348:Zfhx2
|
UTSW |
14 |
55,300,965 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0442:Zfhx2
|
UTSW |
14 |
55,304,357 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0533:Zfhx2
|
UTSW |
14 |
55,301,547 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0561:Zfhx2
|
UTSW |
14 |
55,303,346 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0627:Zfhx2
|
UTSW |
14 |
55,302,784 (GRCm39) |
missense |
probably benign |
|
|
R0659:Zfhx2
|
UTSW |
14 |
55,311,258 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0675:Zfhx2
|
UTSW |
14 |
55,300,620 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1301:Zfhx2
|
UTSW |
14 |
55,300,854 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1563:Zfhx2
|
UTSW |
14 |
55,302,545 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1607:Zfhx2
|
UTSW |
14 |
55,300,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Zfhx2
|
UTSW |
14 |
55,311,401 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1710:Zfhx2
|
UTSW |
14 |
55,303,455 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1879:Zfhx2
|
UTSW |
14 |
55,310,206 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1879:Zfhx2
|
UTSW |
14 |
55,303,074 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1933:Zfhx2
|
UTSW |
14 |
55,312,695 (GRCm39) |
start gained |
probably benign |
|
|
R1944:Zfhx2
|
UTSW |
14 |
55,312,189 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2888:Zfhx2
|
UTSW |
14 |
55,302,260 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2889:Zfhx2
|
UTSW |
14 |
55,302,260 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2915:Zfhx2
|
UTSW |
14 |
55,302,014 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3971:Zfhx2
|
UTSW |
14 |
55,311,932 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4082:Zfhx2
|
UTSW |
14 |
55,302,662 (GRCm39) |
missense |
probably benign |
|
|
R4134:Zfhx2
|
UTSW |
14 |
55,302,600 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4231:Zfhx2
|
UTSW |
14 |
55,310,991 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4675:Zfhx2
|
UTSW |
14 |
55,304,678 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4764:Zfhx2
|
UTSW |
14 |
55,304,372 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4866:Zfhx2
|
UTSW |
14 |
55,302,993 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4940:Zfhx2
|
UTSW |
14 |
55,303,891 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5125:Zfhx2
|
UTSW |
14 |
55,312,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5178:Zfhx2
|
UTSW |
14 |
55,312,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5554:Zfhx2
|
UTSW |
14 |
55,301,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5689:Zfhx2
|
UTSW |
14 |
55,311,360 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5768:Zfhx2
|
UTSW |
14 |
55,311,822 (GRCm39) |
missense |
probably benign |
|
|
R5792:Zfhx2
|
UTSW |
14 |
55,304,303 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5834:Zfhx2
|
UTSW |
14 |
55,310,787 (GRCm39) |
nonsense |
probably null |
|
|
R5895:Zfhx2
|
UTSW |
14 |
55,303,348 (GRCm39) |
missense |
probably benign |
|
|
R5999:Zfhx2
|
UTSW |
14 |
55,311,462 (GRCm39) |
missense |
probably benign |
|
|
R6025:Zfhx2
|
UTSW |
14 |
55,302,665 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6106:Zfhx2
|
UTSW |
14 |
55,305,767 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6135:Zfhx2
|
UTSW |
14 |
55,311,653 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6186:Zfhx2
|
UTSW |
14 |
55,300,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6379:Zfhx2
|
UTSW |
14 |
55,311,795 (GRCm39) |
missense |
probably benign |
|
|
R6725:Zfhx2
|
UTSW |
14 |
55,301,539 (GRCm39) |
nonsense |
probably null |
|
|
R7089:Zfhx2
|
UTSW |
14 |
55,303,229 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7383:Zfhx2
|
UTSW |
14 |
55,305,710 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7470:Zfhx2
|
UTSW |
14 |
55,304,207 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7606:Zfhx2
|
UTSW |
14 |
55,304,120 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7607:Zfhx2
|
UTSW |
14 |
55,303,688 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7698:Zfhx2
|
UTSW |
14 |
55,300,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7730:Zfhx2
|
UTSW |
14 |
55,304,357 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8142:Zfhx2
|
UTSW |
14 |
55,310,895 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8188:Zfhx2
|
UTSW |
14 |
55,301,898 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8212:Zfhx2
|
UTSW |
14 |
55,310,373 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8264:Zfhx2
|
UTSW |
14 |
55,302,969 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8331:Zfhx2
|
UTSW |
14 |
55,309,444 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8369:Zfhx2
|
UTSW |
14 |
55,304,201 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8371:Zfhx2
|
UTSW |
14 |
55,301,549 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8383:Zfhx2
|
UTSW |
14 |
55,311,528 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8415:Zfhx2
|
UTSW |
14 |
55,308,079 (GRCm39) |
missense |
probably benign |
|
|
R8441:Zfhx2
|
UTSW |
14 |
55,303,985 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8466:Zfhx2
|
UTSW |
14 |
55,310,353 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8504:Zfhx2
|
UTSW |
14 |
55,303,243 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8708:Zfhx2
|
UTSW |
14 |
55,312,509 (GRCm39) |
missense |
probably benign |
|
|
R8804:Zfhx2
|
UTSW |
14 |
55,312,191 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8913:Zfhx2
|
UTSW |
14 |
55,309,543 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8952:Zfhx2
|
UTSW |
14 |
55,310,207 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9057:Zfhx2
|
UTSW |
14 |
55,310,027 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9060:Zfhx2
|
UTSW |
14 |
55,311,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9197:Zfhx2
|
UTSW |
14 |
55,312,179 (GRCm39) |
nonsense |
probably null |
|
|
R9622:Zfhx2
|
UTSW |
14 |
55,303,483 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9623:Zfhx2
|
UTSW |
14 |
55,302,191 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9775:Zfhx2
|
UTSW |
14 |
55,304,562 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9780:Zfhx2
|
UTSW |
14 |
55,312,494 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0065:Zfhx2
|
UTSW |
14 |
55,304,417 (GRCm39) |
missense |
probably benign |
0.33 |
|
Z1088:Zfhx2
|
UTSW |
14 |
55,311,637 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
Z1177:Zfhx2
|
UTSW |
14 |
55,304,439 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
Z1177:Zfhx2
|
UTSW |
14 |
55,303,377 (GRCm39) |
missense |
probably benign |
0.40 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGACTCGAAGTCACAGATGTTGC -3'
(R):5'- ACACAGCTTATCCTAAGTGCCCCG -3'
Sequencing Primer
(F):5'- TGGAGCCGTAAGAAGCCC -3'
(R):5'- AAGTGCCCCGCTCATTTC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation