Mutagenetix > Incidental Mutations

Incidental Mutation 'R3547:Hydin'

268263

Institutional Source

Beutler Lab

Gene Symbol

Hydin

Ensembl Gene

ENSMUSG00000059854

Gene Name

HYDIN, axonemal central pair apparatus protein

Synonyms

hy-3, hyrh, hy3, 1700034M11Rik, 4930545D19Rik

MMRRC Submission

040666-MU

Accession Numbers

Ncbi RefSeq: NM_172916; MGI: 2389007

Is this an essential gene?

Possibly essential (E-score: 0.658) question?

Stock #

R3547 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

110266977-110610253 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 110582067 bp

Zygosity

Heterozygous

Amino Acid Change

Glycine to Aspartic acid at position 3995 (G3995D)

Ref Sequence

ENSEMBL: ENSMUSP00000046204 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000043141]

Predicted Effect

possibly damaging
Transcript: ENSMUST00000043141
AA Change: G3995D

PolyPhen 2 Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000046204
Gene: ENSMUSG00000059854
AA Change: G3995D

Domain	Start	End	E-Value	Type
Pfam:Motile_Sperm	246	325	5.6e-8	PFAM
Pfam:ASH	559	659	9.4e-17	PFAM
low complexity region	788	798	N/A	INTRINSIC
Pfam:PapD-like	848	906	1.2e-6	PFAM
low complexity region	998	1024	N/A	INTRINSIC
low complexity region	1279	1292	N/A	INTRINSIC
internal_repeat_6	1317	1549	5.96e-5	PROSPERO
internal_repeat_5	1355	1502	3.23e-5	PROSPERO
low complexity region	1574	1590	N/A	INTRINSIC
internal_repeat_4	1712	1940	5.14e-6	PROSPERO
coiled coil region	1947	1977	N/A	INTRINSIC
low complexity region	2009	2020	N/A	INTRINSIC
low complexity region	2034	2049	N/A	INTRINSIC
SCOP:d1eq1a_	2305	2403	3e-4	SMART
low complexity region	2404	2419	N/A	INTRINSIC
coiled coil region	2543	2588	N/A	INTRINSIC
low complexity region	2636	2656	N/A	INTRINSIC
internal_repeat_7	2772	3008	8.1e-5	PROSPERO
low complexity region	3660	3670	N/A	INTRINSIC
low complexity region	3919	3934	N/A	INTRINSIC
internal_repeat_5	4046	4190	3.23e-5	PROSPERO
internal_repeat_2	4106	4251	6.03e-7	PROSPERO
internal_repeat_4	4317	4532	5.14e-6	PROSPERO
internal_repeat_3	4403	4689	2.05e-6	PROSPERO
internal_repeat_2	4549	4697	6.03e-7	PROSPERO
low complexity region	4951	4964	N/A	INTRINSIC

Meta Mutation Damage Score

0.1717

Coding Region Coverage

1x: 99.1%
3x: 98.5%
10x: 96.9%
20x: 93.9%

Validation Efficiency

98% (62/63)

MGI Phenotype

Strain: 1856913; 3801608
Lethality: D28-D42
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that may be involved in cilia motility. Mutations in this gene cause of autosomal recessive primary ciliary dyskinesia-5, a disorder characterized by the accumulation of cerebrospinal fluid within the ventricles of the brain. A duplicate copy of this gene has been found in humans on chromosome 1. [provided by RefSeq, Jan 2013]
PHENOTYPE: Mice homozygous for a mutation in this gene develop hydrocephaly after birth. Symptoms develop after 3-5 days. Affected animals usually die before 2 months of age. [provided by MGI curators]

Allele List at MGI

All alleles(7) : Targeted(1) Gene trapped(3) Transgenic(1) Spontaneous(2)

Other mutations in this stock

Total: 64 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2010109I03Rik	C	A	15: 74,881,614	A18S	probably null	Het
Alg5	A	G	3: 54,749,315	R316G	probably benign	Het
Anapc1	T	C	2: 128,642,682	N1121D	possibly damaging	Het
Antxr2	A	T	5: 97,977,657	I247N	probably benign	Het
Arid5b	C	T	10: 68,098,462	G294S	probably benign	Het
Arl9	A	G	5: 77,010,479	D136G	probably benign	Het
Atxn1l	A	G	8: 109,732,349	L427P	possibly damaging	Het
Celf3	T	G	3: 94,488,538	C304G	probably damaging	Het
Clcc1	T	A	3: 108,668,113	C169S	probably benign	Het
Clec4a3	A	G	6: 122,964,280	E78G	probably damaging	Het
Clip1	A	G	5: 123,631,078	L532P	probably damaging	Het
Col12a1	T	G	9: 79,633,416	K2429T	probably damaging	Het
Col20a1	G	T	2: 180,994,911	E228D	probably damaging	Het
Cx3cl1	A	C	8: 94,778,124	E56A	possibly damaging	Het
Eprs	G	A	1: 185,379,742		probably null	Het
Fap	A	C	2: 62,519,011	L478R	probably damaging	Het
Fhit	T	C	14: 9,870,095	T125A	probably benign	Het
Gdi1	T	A	X: 74,307,808	F175L	possibly damaging	Het
Golga7b	T	C	19: 42,267,071	M129T	possibly damaging	Het
Gpr149	A	T	3: 62,595,128	C436S	probably benign	Het
Grid2	T	C	6: 64,320,021	V456A	probably damaging	Het
Gstcd	G	T	3: 133,084,838	T56K	possibly damaging	Het
Igkv4-50	G	A	6: 69,700,781	T113I	probably benign	Het
Igkv5-45	A	G	6: 69,776,256		probably benign	Het
Igsf10	G	A	3: 59,330,541	H740Y	probably benign	Het
Igsf10	C	A	3: 59,336,514	R133L	probably damaging	Het
Lcmt1	A	G	7: 123,400,479	E94G	probably benign	Het
Lrp1b	A	T	2: 40,600,288	L287H	probably damaging	Het
Map3k3	C	T	11: 106,142,553	Q211*	probably null	Het
Map4	T	A	9: 110,052,198	F43L	possibly damaging	Het
Mcf2	T	C	X: 60,135,446	K74R	probably damaging	Het
Mylk	G	A	16: 34,880,168	V460I	possibly damaging	Het
Nat1	A	G	8: 67,491,032	D23G	possibly damaging	Het
Nbeal1	T	C	1: 60,278,780	F1959L	probably damaging	Het
Ncf1	T	A	5: 134,226,609	K143*	probably null	Het
Nlrp6	T	G	7: 140,926,769	V849G	probably benign	Het
Olfr549	A	G	7: 102,554,470	Y62C	probably damaging	Het
Pi4k2a	C	T	19: 42,090,548	P16L	probably benign	Het
Pitx3	T	A	19: 46,136,109	Q273L	possibly damaging	Het
Ppp1r27	T	A	11: 120,550,685	I90F	probably damaging	Het
Prickle2	T	C	6: 92,411,137	Y428C	probably damaging	Het
Prkcq	A	G	2: 11,283,816	K527E	probably benign	Het
Prune2	T	A	19: 17,124,348	S2405R	probably damaging	Het
Reln	A	G	5: 22,227,600	V134A	possibly damaging	Het
Rnf167	T	C	11: 70,649,681	I129T	possibly damaging	Het
Rufy4	T	C	1: 74,147,663	C537R	probably damaging	Het
Sfxn2	T	C	19: 46,590,196	S217P	probably damaging	Het
Slc16a7	T	A	10: 125,294,700	K39*	probably null	Het
Slc22a17	A	G	14: 54,907,237	L573P	probably damaging	Het
Slc25a45	T	C	19: 5,884,546	Y181H	probably damaging	Het
Slc6a20a	A	G	9: 123,660,502	S159P	probably damaging	Het
Tbc1d1	G	A	5: 64,286,007	R523Q	probably damaging	Het
Thnsl1	T	G	2: 21,212,627	D397E	probably benign	Het
Ttn	T	A	2: 76,745,106	I25148F	probably damaging	Het
Ube4b	T	C	4: 149,335,116	D1045G	probably damaging	Het
Ugt8a	A	T	3: 125,867,382	L487*	probably null	Het
Uprt	T	A	X: 104,483,328	L123H	probably damaging	Het
Usp9x	T	C	X: 13,128,390	L940P	probably benign	Het
Utp20	T	C	10: 88,782,689	K1150E	probably damaging	Het
Uty	A	C	Y: 1,158,512	D463E	possibly damaging	Het
Vmn1r7	A	G	6: 57,024,849	I142T	possibly damaging	Het
Vps13d	T	G	4: 145,074,975	T3558P	probably damaging	Het
Zfp319	A	G	8: 95,328,817	S253P	probably damaging	Het
Zfp831	A	G	2: 174,657,683	S1265G	probably benign	Het

Other mutations in Hydin

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00338:Hydin	APN	8	110569802	missense	possibly damaging	0.69
IGL00432:Hydin	APN	8	110601252	missense	probably damaging	0.98
IGL01025:Hydin	APN	8	110326401	missense	probably benign	0.38
IGL01140:Hydin	APN	8	110398062	missense	probably benign	0.14
IGL01317:Hydin	APN	8	110326446	missense	probably damaging	0.98
IGL01473:Hydin	APN	8	110312160	missense	probably benign	0.08
IGL01473:Hydin	APN	8	110354953	missense	probably damaging	1.00
IGL01610:Hydin	APN	8	110557713	missense	probably benign	0.00
IGL01685:Hydin	APN	8	110355033	nonsense	probably null
IGL01734:Hydin	APN	8	110490789	nonsense	probably null
IGL01743:Hydin	APN	8	110592776	missense	possibly damaging	0.94
IGL01829:Hydin	APN	8	110589522	missense	possibly damaging	0.68
IGL01919:Hydin	APN	8	110519174	missense	possibly damaging	0.89
IGL01946:Hydin	APN	8	110490718	missense	possibly damaging	0.91
IGL01983:Hydin	APN	8	110514895	missense	probably benign	0.02
IGL02122:Hydin	APN	8	110494415	missense	possibly damaging	0.86
IGL02140:Hydin	APN	8	110566938	missense	probably benign
IGL02158:Hydin	APN	8	110609966	missense	possibly damaging	0.89
IGL02167:Hydin	APN	8	110418423	missense	possibly damaging	0.96
IGL02171:Hydin	APN	8	110451958	nonsense	probably null
IGL02185:Hydin	APN	8	110506476	missense	possibly damaging	0.86
IGL02517:Hydin	APN	8	110566972	missense	probably benign	0.01
IGL02639:Hydin	APN	8	110538449	missense	probably benign	0.01
IGL02644:Hydin	APN	8	110538468	missense	probably damaging	1.00
IGL02652:Hydin	APN	8	110589522	missense	possibly damaging	0.68
IGL02658:Hydin	APN	8	110413276	missense	possibly damaging	0.86
IGL02706:Hydin	APN	8	110410566	missense	probably damaging	0.99
IGL02892:Hydin	APN	8	110598959	missense	possibly damaging	0.89
IGL02947:Hydin	APN	8	110418462	missense	probably damaging	0.96
IGL03136:Hydin	APN	8	110418524	missense	probably benign	0.22
IGL03248:Hydin	APN	8	110595289	missense	probably damaging	0.97
IGL03251:Hydin	APN	8	110490596	missense	probably damaging	1.00
IGL03350:Hydin	APN	8	110312224	missense	possibly damaging	0.86
IGL03366:Hydin	APN	8	110267363	missense	unknown
IGL03404:Hydin	APN	8	110569777	missense	probably benign	0.06
Franz_joseph	UTSW	8	110601318	missense	probably damaging	1.00
maria	UTSW	8	110509127	splice site	probably benign
teresa	UTSW	8	110609671	missense	possibly damaging	0.79
P0005:Hydin	UTSW	8	110494289	critical splice acceptor site	probably null
R0099:Hydin	UTSW	8	110589561	missense	probably damaging	1.00
R0125:Hydin	UTSW	8	110462531	missense	probably benign	0.12
R0157:Hydin	UTSW	8	110300010	missense	possibly damaging	0.86
R0241:Hydin	UTSW	8	110398023	missense	probably benign	0.04
R0241:Hydin	UTSW	8	110398023	missense	probably benign	0.04
R0255:Hydin	UTSW	8	110565018	missense	probably benign	0.00
R0352:Hydin	UTSW	8	110569901	critical splice donor site	probably null
R0379:Hydin	UTSW	8	110509127	splice site	probably benign
R0468:Hydin	UTSW	8	110413223	missense	possibly damaging	0.96
R0477:Hydin	UTSW	8	110418498	missense	probably damaging	1.00
R0479:Hydin	UTSW	8	110599088	missense	probably damaging	1.00
R0539:Hydin	UTSW	8	110523072	missense	probably benign
R0550:Hydin	UTSW	8	110587775	missense	probably benign	0.01
R0571:Hydin	UTSW	8	110514103	splice site	probably null
R0606:Hydin	UTSW	8	110549798	splice site	probably benign
R0789:Hydin	UTSW	8	110566971	missense	possibly damaging	0.53
R0849:Hydin	UTSW	8	110598984	missense	probably damaging	1.00
R0946:Hydin	UTSW	8	110531053	missense	probably benign	0.25
R1201:Hydin	UTSW	8	110569855	missense	probably benign	0.01
R1375:Hydin	UTSW	8	110506222	critical splice donor site	probably null
R1385:Hydin	UTSW	8	110523204	missense	probably benign	0.40
R1411:Hydin	UTSW	8	110575031	missense	probably benign	0.04
R1437:Hydin	UTSW	8	110581985	nonsense	probably null
R1447:Hydin	UTSW	8	110523166	missense	probably damaging	1.00
R1448:Hydin	UTSW	8	110446585	missense	probably benign	0.27
R1466:Hydin	UTSW	8	110532953	missense	possibly damaging	0.47
R1466:Hydin	UTSW	8	110532953	missense	possibly damaging	0.47
R1523:Hydin	UTSW	8	110533271	missense	probably benign	0.05
R1544:Hydin	UTSW	8	110574854	missense	probably benign	0.30
R1581:Hydin	UTSW	8	110410460	missense	probably benign
R1584:Hydin	UTSW	8	110580815	missense	probably benign	0.27
R1598:Hydin	UTSW	8	110410674	missense	possibly damaging	0.96
R1633:Hydin	UTSW	8	110506982	missense	probably benign	0.10
R1777:Hydin	UTSW	8	110589571	missense	probably benign	0.14
R1817:Hydin	UTSW	8	110532827	missense	probably benign	0.00
R1828:Hydin	UTSW	8	110510894	missense	probably benign	0.03
R1837:Hydin	UTSW	8	110569625	missense	probably benign	0.20
R1848:Hydin	UTSW	8	110569808	missense	probably benign	0.19
R1869:Hydin	UTSW	8	110500705	missense	possibly damaging	0.94
R1909:Hydin	UTSW	8	110587772	missense	probably damaging	1.00
R1928:Hydin	UTSW	8	110502947	missense	possibly damaging	0.93
R1950:Hydin	UTSW	8	110609987	missense	possibly damaging	0.64
R2095:Hydin	UTSW	8	110462657	missense	probably damaging	0.96
R2172:Hydin	UTSW	8	110582049	missense	probably benign	0.42
R2217:Hydin	UTSW	8	110418506	missense	probably benign
R2248:Hydin	UTSW	8	110578203	missense	probably benign	0.09
R2272:Hydin	UTSW	8	110309132	missense	probably benign	0.01
R2294:Hydin	UTSW	8	110299959	missense	probably damaging	0.99
R2315:Hydin	UTSW	8	110398044	missense	probably benign	0.01
R2330:Hydin	UTSW	8	110565009	missense	probably benign	0.01
R2374:Hydin	UTSW	8	110565148	missense	probably damaging	1.00
R2446:Hydin	UTSW	8	110587715	missense	possibly damaging	0.82
R2484:Hydin	UTSW	8	110513115	missense	possibly damaging	0.76
R2698:Hydin	UTSW	8	110609929	missense	possibly damaging	0.70
R2843:Hydin	UTSW	8	110519114	missense	probably benign
R2844:Hydin	UTSW	8	110519114	missense	probably benign
R2846:Hydin	UTSW	8	110519114	missense	probably benign
R2882:Hydin	UTSW	8	110566923	missense	possibly damaging	0.92
R2937:Hydin	UTSW	8	110404295	missense	possibly damaging	0.88
R3031:Hydin	UTSW	8	110603216	missense	possibly damaging	0.83
R3038:Hydin	UTSW	8	110582689	missense	probably damaging	1.00
R3121:Hydin	UTSW	8	110506506	missense	probably benign
R3157:Hydin	UTSW	8	110267373	missense	unknown
R3696:Hydin	UTSW	8	110603279	missense	probably damaging	1.00
R3850:Hydin	UTSW	8	110563929	missense	probably damaging	0.99
R3896:Hydin	UTSW	8	110509079	missense	possibly damaging	0.93
R3983:Hydin	UTSW	8	110392325	missense	probably damaging	1.00
R4031:Hydin	UTSW	8	110610047	missense	probably benign	0.30
R4072:Hydin	UTSW	8	110505256	missense	possibly damaging	0.68
R4095:Hydin	UTSW	8	110541547	missense	probably damaging	0.98
R4176:Hydin	UTSW	8	110593820	missense	probably benign	0.00
R4213:Hydin	UTSW	8	110456507	missense	possibly damaging	0.91
R4412:Hydin	UTSW	8	110415736	missense	probably damaging	0.99
R4471:Hydin	UTSW	8	110587132	missense	probably damaging	1.00
R4474:Hydin	UTSW	8	110563865	missense	probably benign	0.11
R4495:Hydin	UTSW	8	110595402	missense	probably damaging	0.99
R4508:Hydin	UTSW	8	110519254	missense	possibly damaging	0.91
R4578:Hydin	UTSW	8	110267339	missense	unknown
R4583:Hydin	UTSW	8	110595225	missense	probably benign	0.36
R4600:Hydin	UTSW	8	110566950	missense	probably benign	0.04
R4681:Hydin	UTSW	8	110506471	missense	possibly damaging	0.85
R4685:Hydin	UTSW	8	110462522	missense	probably damaging	0.99
R4689:Hydin	UTSW	8	110595414	missense	probably benign	0.18
R4735:Hydin	UTSW	8	110555632	critical splice donor site	probably null
R4736:Hydin	UTSW	8	110523208	missense	probably benign	0.02
R4740:Hydin	UTSW	8	110446439	missense	probably benign	0.06
R4771:Hydin	UTSW	8	110532883	missense	probably benign
R4777:Hydin	UTSW	8	110410464	missense	probably damaging	0.98
R4859:Hydin	UTSW	8	110506494	missense	possibly damaging	0.93
R4911:Hydin	UTSW	8	110595438	missense	probably benign	0.01
R4964:Hydin	UTSW	8	110490673	missense	possibly damaging	0.86
R4965:Hydin	UTSW	8	110398095	missense	probably benign
R4989:Hydin	UTSW	8	110563922	missense	possibly damaging	0.84
R4995:Hydin	UTSW	8	110569642	missense	probably damaging	0.97
R5059:Hydin	UTSW	8	110505769	missense	probably damaging	0.96
R5071:Hydin	UTSW	8	110538473	missense	probably benign	0.03
R5073:Hydin	UTSW	8	110538473	missense	probably benign	0.03
R5092:Hydin	UTSW	8	110582668	missense	probably benign	0.16
R5156:Hydin	UTSW	8	110609701	missense	probably benign	0.00
R5166:Hydin	UTSW	8	110523142	missense	possibly damaging	0.89
R5189:Hydin	UTSW	8	110413211	critical splice acceptor site	probably null
R5243:Hydin	UTSW	8	110505748	missense	possibly damaging	0.92
R5244:Hydin	UTSW	8	110532819	missense	possibly damaging	0.77
R5256:Hydin	UTSW	8	110587223	missense	possibly damaging	0.92
R5266:Hydin	UTSW	8	110334784	missense	possibly damaging	0.87
R5283:Hydin	UTSW	8	110451980	missense	possibly damaging	0.96
R5343:Hydin	UTSW	8	110485419	missense	probably benign	0.40
R5359:Hydin	UTSW	8	110538372	missense	probably benign	0.00
R5390:Hydin	UTSW	8	110595467	missense	probably benign
R5394:Hydin	UTSW	8	110539842	splice site	probably null
R5441:Hydin	UTSW	8	110565109	missense	possibly damaging	0.72
R5461:Hydin	UTSW	8	110519231	missense	probably damaging	0.96
R5662:Hydin	UTSW	8	110580709	missense	probably benign	0.02
R5695:Hydin	UTSW	8	110535283	missense	probably benign	0.35
R5732:Hydin	UTSW	8	110452058	missense	probably benign	0.03
R5774:Hydin	UTSW	8	110571915	nonsense	probably null
R5780:Hydin	UTSW	8	110586080	missense	probably damaging	1.00
R5787:Hydin	UTSW	8	110326353	missense	probably damaging	0.99
R5802:Hydin	UTSW	8	110452060	missense	possibly damaging	0.86
R5841:Hydin	UTSW	8	110533214	missense	possibly damaging	0.76
R5856:Hydin	UTSW	8	110541842	missense	probably damaging	0.99
R5893:Hydin	UTSW	8	110490676	missense	probably benign	0.12
R5963:Hydin	UTSW	8	110494294	missense	possibly damaging	0.93
R6008:Hydin	UTSW	8	110599085	missense	probably benign	0.02
R6019:Hydin	UTSW	8	110566620	missense	probably benign
R6038:Hydin	UTSW	8	110599031	missense	probably benign	0.16
R6038:Hydin	UTSW	8	110599031	missense	probably benign	0.16
R6133:Hydin	UTSW	8	110601276	missense	probably benign	0.00
R6135:Hydin	UTSW	8	110462660	missense	possibly damaging	0.85
R6157:Hydin	UTSW	8	110528016	missense	probably benign
R6209:Hydin	UTSW	8	110593802	missense	probably benign	0.05
R6238:Hydin	UTSW	8	110392111	intron	probably null
R6293:Hydin	UTSW	8	110597911	missense	possibly damaging	0.83
R6340:Hydin	UTSW	8	110354942	splice site	probably null
R6349:Hydin	UTSW	8	110418459	nonsense	probably null
R6357:Hydin	UTSW	8	110541657	missense	possibly damaging	0.86
R6385:Hydin	UTSW	8	110312224	missense	possibly damaging	0.86
R6396:Hydin	UTSW	8	110506889	missense	probably damaging	0.96
R6466:Hydin	UTSW	8	110506968	missense	possibly damaging	0.85
R6648:Hydin	UTSW	8	110525667	intron	probably null
R6671:Hydin	UTSW	8	110601318	missense	probably damaging	1.00
R6695:Hydin	UTSW	8	110326460	missense	probably benign	0.05
R6800:Hydin	UTSW	8	110597971	missense	probably benign	0.09
R6841:Hydin	UTSW	8	110538375	missense	probably benign	0.09
R6867:Hydin	UTSW	8	110539802	missense	probably benign	0.08
R6889:Hydin	UTSW	8	110532856	missense	possibly damaging	0.79
R6895:Hydin	UTSW	8	110312251	missense	probably benign	0.00
R6940:Hydin	UTSW	8	110490611	missense	probably damaging	1.00
R6951:Hydin	UTSW	8	110398125	missense	probably benign
R6980:Hydin	UTSW	8	110413284	missense	possibly damaging	0.91
R6981:Hydin	UTSW	8	110531072	missense	possibly damaging	0.89
R7061:Hydin	UTSW	8	110603288	missense	possibly damaging	0.90
R7085:Hydin	UTSW	8	110603330	missense	probably benign	0.03
R7086:Hydin	UTSW	8	110600245	missense	possibly damaging	0.68
R7110:Hydin	UTSW	8	110354951	critical splice acceptor site	probably null
R7158:Hydin	UTSW	8	110609671	missense	possibly damaging	0.79
R7163:Hydin	UTSW	8	110603336	missense	probably benign	0.25
R7209:Hydin	UTSW	8	110489792	nonsense	probably null
R7244:Hydin	UTSW	8	110549675	missense	probably damaging	0.98
R7347:Hydin	UTSW	8	110600362	missense	probably benign	0.06
R7349:Hydin	UTSW	8	110398171	splice site	probably null
R7359:Hydin	UTSW	8	110506101	missense	probably damaging	0.98
R7365:Hydin	UTSW	8	110557662	missense	probably damaging	0.99
R7365:Hydin	UTSW	8	110601273	missense	probably damaging	1.00
R7436:Hydin	UTSW	8	110583914	missense	probably damaging	0.96
R7528:Hydin	UTSW	8	110380572	nonsense	probably null
R7544:Hydin	UTSW	8	110589525	missense	probably benign	0.35
R7625:Hydin	UTSW	8	110541844	missense	probably benign	0.01
R7713:Hydin	UTSW	8	110593812	missense	possibly damaging	0.69
R7763:Hydin	UTSW	8	110505843	missense	possibly damaging	0.92
R7771:Hydin	UTSW	8	110565085	missense	probably damaging	0.97
R7794:Hydin	UTSW	8	110509083	missense	probably damaging	1.00
R7894:Hydin	UTSW	8	110513010	missense	possibly damaging	0.88
R7899:Hydin	UTSW	8	110587748	missense	probably benign	0.00
R7908:Hydin	UTSW	8	110510867	missense	probably benign	0.01
R7912:Hydin	UTSW	8	110555607	missense	possibly damaging	0.68
R7916:Hydin	UTSW	8	110589460	missense	probably damaging	0.99
R7977:Hydin	UTSW	8	110513010	missense	possibly damaging	0.88
R7982:Hydin	UTSW	8	110587748	missense	probably benign	0.00
R7989:Hydin	UTSW	8	110510867	missense	probably benign	0.01
R7993:Hydin	UTSW	8	110555607	missense	possibly damaging	0.68
R8011:Hydin	UTSW	8	110583909	missense	probably damaging	1.00
R8041:Hydin	UTSW	8	110574994	missense	probably benign	0.02
X0063:Hydin	UTSW	8	110551319	missense	probably damaging	1.00
Z1088:Hydin	UTSW	8	110299973	missense	probably benign	0.12
Z1088:Hydin	UTSW	8	110586048	missense	probably benign	0.00
Z1088:Hydin	UTSW	8	110592791	frame shift	probably null
Z1176:Hydin	UTSW	8	110541600	missense	possibly damaging	0.65
Z1177:Hydin	UTSW	8	110380610	missense	probably damaging	1.00
Z1177:Hydin	UTSW	8	110450232	missense	possibly damaging	0.47
Z1177:Hydin	UTSW	8	110587142	frame shift	probably null
Z1177:Hydin	UTSW	8	110609989	missense	probably benign	0.10

Predicted Primers

PCR Primer
(F):5'- TTTCCAACCAGCTAAGAAAGGGAC -3'
(R):5'- CCTCGAGATGTCCAGTTTGC -3'

Sequencing Primer
(F):5'- CCAGCTAAGAAAGGGACAACGG -3'
(R):5'- GCTTCTAGGCATCAGCATGG -3'

Posted On

2015-02-19