Incidental Mutation 'R7361:Plxna4'
| ID |
571330 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxna4
|
| Ensembl Gene |
ENSMUSG00000029765 |
| Gene Name |
plexin A4 |
| Synonyms |
Plxa4 |
| MMRRC Submission |
045447-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.600)
|
| Stock # |
R7361 (G1)
|
| Quality Score |
221.009 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
32121478-32565127 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 32173057 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110748
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000115096]
|
| AlphaFold |
Q80UG2 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000115096
|
| SMART Domains |
Protein: ENSMUSP00000110748
Gene: ENSMUSG00000029765
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Sema
|
50 |
490 |
2.3e-131 |
SMART |
|
PSI
|
508 |
558 |
2.21e-14 |
SMART |
|
PSI
|
654 |
701 |
2.44e-7 |
SMART |
|
PSI
|
802 |
855 |
1.2e-6 |
SMART |
|
IPT
|
856 |
950 |
7.25e-16 |
SMART |
|
IPT
|
952 |
1036 |
4.1e-15 |
SMART |
|
IPT
|
1038 |
1138 |
2.86e-14 |
SMART |
|
IPT
|
1140 |
1229 |
6.88e-1 |
SMART |
|
transmembrane domain
|
1237 |
1259 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1310 |
1863 |
1.8e-264 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mice exhibit defective trajecotory and projection of peripheral sensory axons and sympathetic ganglion axons and the formation of the anterior commissure and the barrels. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(2) : Targeted, knock-out(2) |
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A630073D07Rik |
C |
T |
6: 132,604,434 (GRCm39) |
V4I |
unknown |
Het |
| Actn1 |
A |
T |
12: 80,240,489 (GRCm39) |
D199E |
probably benign |
Het |
| Adam17 |
T |
C |
12: 21,375,602 (GRCm39) |
D739G |
probably damaging |
Het |
| Agmat |
T |
C |
4: 141,474,163 (GRCm39) |
S15P |
probably benign |
Het |
| Ahsa2 |
A |
G |
11: 23,441,099 (GRCm39) |
S229P |
probably damaging |
Het |
| Arhgef3 |
A |
G |
14: 26,987,535 (GRCm39) |
D36G |
possibly damaging |
Het |
| C6 |
C |
A |
15: 4,826,404 (GRCm39) |
Y662* |
probably null |
Het |
| Ccs |
T |
C |
19: 4,883,378 (GRCm39) |
D140G |
probably benign |
Het |
| Cdc42bpb |
A |
G |
12: 111,312,039 (GRCm39) |
L65P |
probably damaging |
Het |
| Cdh24 |
A |
T |
14: 54,876,378 (GRCm39) |
V149E |
possibly damaging |
Het |
| Cdk12 |
C |
A |
11: 98,101,294 (GRCm39) |
S384* |
probably null |
Het |
| Cep350 |
G |
A |
1: 155,777,237 (GRCm39) |
A1701V |
probably damaging |
Het |
| Ces1g |
T |
C |
8: 94,060,307 (GRCm39) |
Q104R |
not run |
Het |
| Chd5 |
A |
G |
4: 152,447,745 (GRCm39) |
H537R |
probably damaging |
Het |
| Cln5 |
T |
A |
14: 103,313,339 (GRCm39) |
V197D |
probably damaging |
Het |
| Coq7 |
A |
G |
7: 118,128,798 (GRCm39) |
V79A |
probably benign |
Het |
| Cp |
A |
T |
3: 20,018,470 (GRCm39) |
N58I |
probably benign |
Het |
| Cplx2 |
A |
T |
13: 54,526,639 (GRCm39) |
M16L |
probably benign |
Het |
| Crot |
A |
G |
5: 9,027,534 (GRCm39) |
L266S |
probably damaging |
Het |
| Ctbs |
T |
A |
3: 146,164,509 (GRCm39) |
Y221N |
probably damaging |
Het |
| Cul7 |
T |
A |
17: 46,967,933 (GRCm39) |
L707Q |
probably damaging |
Het |
| D430041D05Rik |
G |
A |
2: 104,085,363 (GRCm39) |
T378I |
possibly damaging |
Het |
| Dixdc1 |
T |
C |
9: 50,599,953 (GRCm39) |
I364V |
probably damaging |
Het |
| Dnah11 |
T |
A |
12: 117,982,477 (GRCm39) |
H2564L |
probably damaging |
Het |
| Dnajc3 |
T |
C |
14: 119,175,576 (GRCm39) |
Y26H |
probably benign |
Het |
| Dpysl2 |
G |
A |
14: 67,071,664 (GRCm39) |
H159Y |
possibly damaging |
Het |
| Ehmt1 |
T |
A |
2: 24,746,713 (GRCm39) |
K423I |
possibly damaging |
Het |
| Eif1ad4 |
A |
G |
12: 87,862,170 (GRCm39) |
N11D |
unknown |
Het |
| Enpp7 |
A |
G |
11: 118,882,985 (GRCm39) |
N353S |
probably benign |
Het |
| Ext1 |
G |
A |
15: 53,208,119 (GRCm39) |
A214V |
probably damaging |
Het |
| Fbh1 |
A |
T |
2: 11,751,887 (GRCm39) |
I937N |
probably damaging |
Het |
| Fbxo39 |
T |
C |
11: 72,207,800 (GRCm39) |
Y51H |
possibly damaging |
Het |
| Firrm |
A |
T |
1: 163,813,602 (GRCm39) |
D207E |
possibly damaging |
Het |
| Fry |
A |
G |
5: 150,360,312 (GRCm39) |
H1986R |
possibly damaging |
Het |
| Grem2 |
T |
C |
1: 174,664,514 (GRCm39) |
K112E |
probably benign |
Het |
| Gucy1a1 |
A |
G |
3: 82,005,027 (GRCm39) |
V586A |
probably damaging |
Het |
| Il12rb2 |
G |
T |
6: 67,280,450 (GRCm39) |
L586I |
possibly damaging |
Het |
| Il18 |
T |
C |
9: 50,490,614 (GRCm39) |
I83T |
probably damaging |
Het |
| Irs1 |
A |
T |
1: 82,266,835 (GRCm39) |
Y460* |
probably null |
Het |
| Jak1 |
G |
T |
4: 101,041,536 (GRCm39) |
Q161K |
possibly damaging |
Het |
| Jakmip1 |
T |
A |
5: 37,276,148 (GRCm39) |
L486Q |
probably damaging |
Het |
| Jmjd1c |
C |
A |
10: 67,054,143 (GRCm39) |
Q16K |
probably benign |
Het |
| Kidins220 |
T |
C |
12: 25,106,999 (GRCm39) |
L1393P |
probably benign |
Het |
| Klhl24 |
A |
C |
16: 19,936,750 (GRCm39) |
I453L |
probably benign |
Het |
| Krtap2-4 |
C |
T |
11: 99,505,420 (GRCm39) |
D64N |
probably damaging |
Het |
| Man1a |
T |
A |
10: 53,784,105 (GRCm39) |
D592V |
probably damaging |
Het |
| Mepe |
T |
A |
5: 104,485,009 (GRCm39) |
Y50N |
probably benign |
Het |
| Mier3 |
G |
A |
13: 111,841,783 (GRCm39) |
G115S |
possibly damaging |
Het |
| Muc4 |
T |
A |
16: 32,754,670 (GRCm38) |
S1515T |
probably benign |
Het |
| Nalcn |
T |
C |
14: 123,529,251 (GRCm39) |
D1408G |
probably benign |
Het |
| Nav1 |
T |
C |
1: 135,380,591 (GRCm39) |
M1443V |
unknown |
Het |
| Nckap1l |
A |
C |
15: 103,379,709 (GRCm39) |
N332T |
possibly damaging |
Het |
| Neurl4 |
T |
A |
11: 69,802,905 (GRCm39) |
L1467Q |
probably benign |
Het |
| Notch2 |
A |
G |
3: 98,038,718 (GRCm39) |
N1287S |
probably benign |
Het |
| Nr4a3 |
C |
T |
4: 48,083,203 (GRCm39) |
P579S |
probably benign |
Het |
| Nrxn2 |
A |
T |
19: 6,567,112 (GRCm39) |
H1329L |
probably benign |
Het |
| Nynrin |
A |
T |
14: 56,107,857 (GRCm39) |
H988L |
possibly damaging |
Het |
| Or1e34 |
T |
A |
11: 73,778,827 (GRCm39) |
I124F |
probably damaging |
Het |
| Or4c31 |
A |
G |
2: 88,291,836 (GRCm39) |
T70A |
probably benign |
Het |
| Or4c3d |
A |
G |
2: 89,882,089 (GRCm39) |
I193T |
probably benign |
Het |
| Or52e3 |
G |
T |
7: 102,869,830 (GRCm39) |
D302Y |
possibly damaging |
Het |
| Or7g35 |
T |
A |
9: 19,495,856 (GRCm39) |
F8I |
probably benign |
Het |
| Pclo |
G |
A |
5: 14,843,882 (GRCm39) |
S1534N |
probably damaging |
Het |
| Pign |
A |
G |
1: 105,512,778 (GRCm39) |
V635A |
probably benign |
Het |
| Pkhd1 |
T |
C |
1: 20,664,177 (GRCm39) |
T134A |
probably damaging |
Het |
| Plcb4 |
A |
T |
2: 135,818,068 (GRCm39) |
N790I |
possibly damaging |
Het |
| Plxna2 |
G |
T |
1: 194,482,087 (GRCm39) |
C1453F |
probably damaging |
Het |
| Pnpla2 |
A |
G |
7: 141,037,344 (GRCm39) |
I116V |
possibly damaging |
Het |
| Polq |
A |
G |
16: 36,880,790 (GRCm39) |
T985A |
probably benign |
Het |
| Pramel11 |
T |
C |
4: 143,622,456 (GRCm39) |
T300A |
possibly damaging |
Het |
| Prex1 |
T |
C |
2: 166,555,490 (GRCm39) |
N50S |
probably benign |
Het |
| Ptgfrn |
G |
A |
3: 100,984,760 (GRCm39) |
A144V |
probably benign |
Het |
| Rad54b |
G |
A |
4: 11,599,782 (GRCm39) |
G329S |
probably damaging |
Het |
| Rrbp1 |
A |
G |
2: 143,809,364 (GRCm39) |
L931S |
probably benign |
Het |
| Saxo4 |
T |
G |
19: 10,456,943 (GRCm39) |
D134A |
probably damaging |
Het |
| Sipa1l2 |
A |
G |
8: 126,180,071 (GRCm39) |
S1109P |
probably damaging |
Het |
| Slc26a7 |
G |
T |
4: 14,546,305 (GRCm39) |
N341K |
probably damaging |
Het |
| Smg1 |
A |
C |
7: 117,784,200 (GRCm39) |
D958E |
unknown |
Het |
| Smg6 |
T |
A |
11: 74,820,979 (GRCm39) |
S417T |
probably benign |
Het |
| Srgap3 |
A |
G |
6: 112,723,882 (GRCm39) |
V550A |
probably damaging |
Het |
| Terb1 |
T |
A |
8: 105,195,431 (GRCm39) |
D570V |
probably damaging |
Het |
| Tet3 |
A |
G |
6: 83,345,076 (GRCm39) |
V1787A |
probably benign |
Het |
| Tor1a |
A |
T |
2: 30,853,753 (GRCm39) |
D192E |
probably benign |
Het |
| Tpr |
T |
C |
1: 150,323,372 (GRCm39) |
S2379P |
possibly damaging |
Het |
| Trip12 |
A |
T |
1: 84,728,163 (GRCm39) |
F1138L |
probably damaging |
Het |
| Trpv1 |
T |
C |
11: 73,151,203 (GRCm39) |
L797P |
probably damaging |
Het |
| Tut1 |
T |
C |
19: 8,942,698 (GRCm39) |
L595P |
probably damaging |
Het |
| Ubl7 |
T |
C |
9: 57,821,905 (GRCm39) |
S85P |
probably damaging |
Het |
| Urb1 |
C |
A |
16: 90,571,656 (GRCm39) |
S1051I |
probably damaging |
Het |
| Usp17le |
A |
G |
7: 104,418,084 (GRCm39) |
W353R |
probably damaging |
Het |
| Usp44 |
T |
C |
10: 93,682,330 (GRCm39) |
L260S |
probably benign |
Het |
| Wsb1 |
T |
A |
11: 79,131,623 (GRCm39) |
|
probably null |
Het |
| Xrcc2 |
A |
T |
5: 25,897,755 (GRCm39) |
C65S |
probably damaging |
Het |
| Zfp316 |
T |
A |
5: 143,240,430 (GRCm39) |
M530L |
probably benign |
Het |
| Zfp473 |
T |
C |
7: 44,382,563 (GRCm39) |
H590R |
probably damaging |
Het |
| Zfp983 |
T |
A |
17: 21,880,850 (GRCm39) |
H259Q |
probably damaging |
Het |
|
| Other mutations in Plxna4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Plxna4
|
APN |
6 |
32,139,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01395:Plxna4
|
APN |
6 |
32,216,368 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01506:Plxna4
|
APN |
6 |
32,493,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01606:Plxna4
|
APN |
6 |
32,134,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01753:Plxna4
|
APN |
6 |
32,287,413 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01767:Plxna4
|
APN |
6 |
32,214,613 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01968:Plxna4
|
APN |
6 |
32,192,139 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02109:Plxna4
|
APN |
6 |
32,192,576 (GRCm39) |
missense |
probably benign |
|
|
IGL02299:Plxna4
|
APN |
6 |
32,142,091 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02306:Plxna4
|
APN |
6 |
32,183,059 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02312:Plxna4
|
APN |
6 |
32,142,052 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL02326:Plxna4
|
APN |
6 |
32,129,840 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02658:Plxna4
|
APN |
6 |
32,162,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02683:Plxna4
|
APN |
6 |
32,494,541 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02701:Plxna4
|
APN |
6 |
32,494,494 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02995:Plxna4
|
APN |
6 |
32,493,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03030:Plxna4
|
APN |
6 |
32,179,160 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03264:Plxna4
|
APN |
6 |
32,155,337 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL03304:Plxna4
|
APN |
6 |
32,141,986 (GRCm39) |
splice site |
probably benign |
|
|
IGL03382:Plxna4
|
APN |
6 |
32,179,129 (GRCm39) |
missense |
probably benign |
0.23 |
|
corona
|
UTSW |
6 |
32,494,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Disposed
|
UTSW |
6 |
32,493,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
inclined
|
UTSW |
6 |
32,214,658 (GRCm39) |
nonsense |
probably null |
|
|
Slope
|
UTSW |
6 |
32,211,541 (GRCm39) |
missense |
probably benign |
0.00 |
|
G4846:Plxna4
|
UTSW |
6 |
32,169,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0133:Plxna4
|
UTSW |
6 |
32,174,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0200:Plxna4
|
UTSW |
6 |
32,174,023 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0308:Plxna4
|
UTSW |
6 |
32,214,703 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0468:Plxna4
|
UTSW |
6 |
32,192,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0505:Plxna4
|
UTSW |
6 |
32,179,054 (GRCm39) |
missense |
probably benign |
|
|
R0542:Plxna4
|
UTSW |
6 |
32,169,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0548:Plxna4
|
UTSW |
6 |
32,134,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Plxna4
|
UTSW |
6 |
32,162,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1144:Plxna4
|
UTSW |
6 |
32,174,091 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1190:Plxna4
|
UTSW |
6 |
32,228,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1228:Plxna4
|
UTSW |
6 |
32,201,087 (GRCm39) |
splice site |
probably null |
|
|
R1569:Plxna4
|
UTSW |
6 |
32,162,410 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1803:Plxna4
|
UTSW |
6 |
32,494,379 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1832:Plxna4
|
UTSW |
6 |
32,174,761 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2068:Plxna4
|
UTSW |
6 |
32,494,551 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2157:Plxna4
|
UTSW |
6 |
32,493,909 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2842:Plxna4
|
UTSW |
6 |
32,192,566 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2849:Plxna4
|
UTSW |
6 |
32,162,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2892:Plxna4
|
UTSW |
6 |
32,493,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2930:Plxna4
|
UTSW |
6 |
32,142,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3892:Plxna4
|
UTSW |
6 |
32,192,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4065:Plxna4
|
UTSW |
6 |
32,213,300 (GRCm39) |
nonsense |
probably null |
|
|
R4276:Plxna4
|
UTSW |
6 |
32,177,883 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4307:Plxna4
|
UTSW |
6 |
32,140,444 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4331:Plxna4
|
UTSW |
6 |
32,127,480 (GRCm39) |
nonsense |
probably null |
|
|
R4478:Plxna4
|
UTSW |
6 |
32,173,068 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4529:Plxna4
|
UTSW |
6 |
32,473,831 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4566:Plxna4
|
UTSW |
6 |
32,494,338 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4568:Plxna4
|
UTSW |
6 |
32,129,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4664:Plxna4
|
UTSW |
6 |
32,493,885 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4685:Plxna4
|
UTSW |
6 |
32,142,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Plxna4
|
UTSW |
6 |
32,493,623 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4939:Plxna4
|
UTSW |
6 |
32,142,697 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5153:Plxna4
|
UTSW |
6 |
32,201,094 (GRCm39) |
splice site |
probably null |
|
|
R5181:Plxna4
|
UTSW |
6 |
32,493,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5256:Plxna4
|
UTSW |
6 |
32,228,007 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5259:Plxna4
|
UTSW |
6 |
32,493,956 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5306:Plxna4
|
UTSW |
6 |
32,183,056 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5487:Plxna4
|
UTSW |
6 |
32,494,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5510:Plxna4
|
UTSW |
6 |
32,155,293 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5542:Plxna4
|
UTSW |
6 |
32,183,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Plxna4
|
UTSW |
6 |
32,134,915 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R5634:Plxna4
|
UTSW |
6 |
32,214,658 (GRCm39) |
nonsense |
probably null |
|
|
R5653:Plxna4
|
UTSW |
6 |
32,494,551 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5665:Plxna4
|
UTSW |
6 |
32,192,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5845:Plxna4
|
UTSW |
6 |
32,214,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Plxna4
|
UTSW |
6 |
32,494,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5938:Plxna4
|
UTSW |
6 |
32,211,541 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5973:Plxna4
|
UTSW |
6 |
32,228,000 (GRCm39) |
splice site |
probably null |
|
|
R6433:Plxna4
|
UTSW |
6 |
32,192,613 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6482:Plxna4
|
UTSW |
6 |
32,493,672 (GRCm39) |
missense |
probably benign |
|
|
R6560:Plxna4
|
UTSW |
6 |
32,192,613 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6721:Plxna4
|
UTSW |
6 |
32,177,794 (GRCm39) |
missense |
probably benign |
0.26 |
|
R6810:Plxna4
|
UTSW |
6 |
32,287,457 (GRCm39) |
missense |
probably benign |
0.18 |
|
R6985:Plxna4
|
UTSW |
6 |
32,214,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7024:Plxna4
|
UTSW |
6 |
32,169,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7046:Plxna4
|
UTSW |
6 |
32,493,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7137:Plxna4
|
UTSW |
6 |
32,494,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7163:Plxna4
|
UTSW |
6 |
32,473,691 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7199:Plxna4
|
UTSW |
6 |
32,192,113 (GRCm39) |
nonsense |
probably null |
|
|
R7248:Plxna4
|
UTSW |
6 |
32,139,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7260:Plxna4
|
UTSW |
6 |
32,216,455 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7383:Plxna4
|
UTSW |
6 |
32,129,734 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7405:Plxna4
|
UTSW |
6 |
32,173,254 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Plxna4
|
UTSW |
6 |
32,214,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7635:Plxna4
|
UTSW |
6 |
32,473,676 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7754:Plxna4
|
UTSW |
6 |
32,129,807 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7763:Plxna4
|
UTSW |
6 |
32,200,915 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7789:Plxna4
|
UTSW |
6 |
32,183,168 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8167:Plxna4
|
UTSW |
6 |
32,493,981 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8191:Plxna4
|
UTSW |
6 |
32,493,885 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8225:Plxna4
|
UTSW |
6 |
32,139,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8284:Plxna4
|
UTSW |
6 |
32,129,789 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8305:Plxna4
|
UTSW |
6 |
32,188,000 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8438:Plxna4
|
UTSW |
6 |
32,179,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8493:Plxna4
|
UTSW |
6 |
32,192,647 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8714:Plxna4
|
UTSW |
6 |
32,140,379 (GRCm39) |
nonsense |
probably null |
|
|
R8759:Plxna4
|
UTSW |
6 |
32,169,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8822:Plxna4
|
UTSW |
6 |
32,127,431 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8844:Plxna4
|
UTSW |
6 |
32,174,026 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8974:Plxna4
|
UTSW |
6 |
32,216,447 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9020:Plxna4
|
UTSW |
6 |
32,211,497 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9144:Plxna4
|
UTSW |
6 |
32,162,496 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9206:Plxna4
|
UTSW |
6 |
32,494,379 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9208:Plxna4
|
UTSW |
6 |
32,494,379 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9257:Plxna4
|
UTSW |
6 |
32,139,018 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9269:Plxna4
|
UTSW |
6 |
32,155,315 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9411:Plxna4
|
UTSW |
6 |
32,159,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9469:Plxna4
|
UTSW |
6 |
32,494,526 (GRCm39) |
missense |
probably benign |
|
|
R9583:Plxna4
|
UTSW |
6 |
32,192,169 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9647:Plxna4
|
UTSW |
6 |
32,228,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9695:Plxna4
|
UTSW |
6 |
32,183,056 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9801:Plxna4
|
UTSW |
6 |
32,140,526 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
V1024:Plxna4
|
UTSW |
6 |
32,211,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Plxna4
|
UTSW |
6 |
32,493,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATTACCTCCAAATGCTGCC -3'
(R):5'- ATGGTATACATCGCCCCAGACAG -3'
Sequencing Primer
(F):5'- CCAGGCTGGTTGGTACAGTACAG -3'
(R):5'- CCAGACAGCCCGCTCAG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation