Incidental Mutation 'R7387:Sgsm1'
| ID |
573164 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sgsm1
|
| Ensembl Gene |
ENSMUSG00000042216 |
| Gene Name |
small G protein signaling modulator 1 |
| Synonyms |
Rutbc2, D5Bwg1524e, 2410098H20Rik |
| MMRRC Submission |
045469-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7387 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
113391086-113458652 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 113411566 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Cysteine
at position 720
(F720C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000046544
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048112]
[ENSMUST00000057209]
[ENSMUST00000112325]
[ENSMUST00000154248]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000048112
AA Change: F720C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000046544
Gene: ENSMUSG00000042216
AA Change: F720C
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
469 |
N/A |
INTRINSIC |
|
TBC
|
559 |
1053 |
2.88e-29 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057209
AA Change: F433C
PolyPhen 2
Score 0.677 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000084106
Gene: ENSMUSG00000042216
AA Change: F433C
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
114 |
126 |
N/A |
INTRINSIC |
|
low complexity region
|
167 |
182 |
N/A |
INTRINSIC |
|
TBC
|
272 |
766 |
2.88e-29 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112325
|
| SMART Domains |
Protein: ENSMUSP00000107944
Gene: ENSMUSG00000042216
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
454 |
469 |
N/A |
INTRINSIC |
|
SCOP:d1fkma1
|
539 |
615 |
1e-6 |
SMART |
|
Blast:TBC
|
559 |
675 |
1e-71 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154248
|
| SMART Domains |
Protein: ENSMUSP00000114932
Gene: ENSMUSG00000042216
| Domain | Start | End | E-Value | Type |
|---|
|
RUN
|
127 |
187 |
6.52e-18 |
SMART |
|
low complexity region
|
401 |
413 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
524 |
N/A |
INTRINSIC |
|
SCOP:d1fkma1
|
594 |
670 |
9e-7 |
SMART |
|
Blast:TBC
|
614 |
706 |
3e-55 |
BLAST |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522H14Rik |
A |
G |
4: 109,362,774 (GRCm39) |
Y182H |
probably damaging |
Het |
| Abca6 |
A |
G |
11: 110,093,246 (GRCm39) |
V1009A |
probably benign |
Het |
| Abcg2 |
A |
T |
6: 58,666,609 (GRCm39) |
I573F |
possibly damaging |
Het |
| Adck1 |
A |
G |
12: 88,427,822 (GRCm39) |
T480A |
probably benign |
Het |
| Adcy5 |
T |
C |
16: 35,092,460 (GRCm39) |
I607T |
probably damaging |
Het |
| Add2 |
A |
G |
6: 86,062,997 (GRCm39) |
K52E |
probably damaging |
Het |
| Arid4a |
T |
A |
12: 71,134,270 (GRCm39) |
S1191T |
probably damaging |
Het |
| Atg2a |
G |
T |
19: 6,305,198 (GRCm39) |
C1207F |
possibly damaging |
Het |
| Atg2b |
T |
C |
12: 105,589,034 (GRCm39) |
D1875G |
probably damaging |
Het |
| B3gntl1 |
A |
G |
11: 121,520,741 (GRCm39) |
L224P |
possibly damaging |
Het |
| BC035947 |
A |
G |
1: 78,475,098 (GRCm39) |
V478A |
possibly damaging |
Het |
| Cachd1 |
T |
C |
4: 100,634,375 (GRCm39) |
V17A |
unknown |
Het |
| Cad |
T |
C |
5: 31,219,284 (GRCm39) |
Y669H |
probably damaging |
Het |
| Ccdc110 |
A |
T |
8: 46,395,233 (GRCm39) |
M375L |
probably benign |
Het |
| Cdc6 |
C |
T |
11: 98,799,042 (GRCm39) |
|
probably benign |
Het |
| Cdhr4 |
T |
A |
9: 107,874,111 (GRCm39) |
Y72* |
probably null |
Het |
| Cenpe |
T |
G |
3: 134,952,798 (GRCm39) |
M1496R |
probably benign |
Het |
| Clec4a1 |
T |
G |
6: 122,899,016 (GRCm39) |
C28W |
possibly damaging |
Het |
| Cma2 |
A |
G |
14: 56,210,505 (GRCm39) |
N120S |
probably benign |
Het |
| Cped1 |
A |
T |
6: 22,059,933 (GRCm39) |
I200L |
probably benign |
Het |
| Cpsf1 |
A |
T |
15: 76,486,766 (GRCm39) |
S257T |
possibly damaging |
Het |
| Dnah6 |
G |
A |
6: 73,189,595 (GRCm39) |
Q18* |
probably null |
Het |
| Dpp10 |
T |
C |
1: 123,268,869 (GRCm39) |
E720G |
probably benign |
Het |
| Dus2 |
G |
A |
8: 106,772,619 (GRCm39) |
R243Q |
probably damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,157,932 (GRCm39) |
N769S |
possibly damaging |
Het |
| Ece1 |
T |
A |
4: 137,666,095 (GRCm39) |
I313N |
possibly damaging |
Het |
| Ern1 |
A |
T |
11: 106,312,778 (GRCm39) |
V201E |
probably damaging |
Het |
| Exoc3l |
A |
G |
8: 106,021,605 (GRCm39) |
L141P |
probably damaging |
Het |
| Fam168b |
G |
A |
1: 34,858,789 (GRCm39) |
T131M |
probably damaging |
Het |
| Fez1 |
T |
C |
9: 36,779,108 (GRCm39) |
F262L |
probably damaging |
Het |
| H2-DMa |
T |
C |
17: 34,357,101 (GRCm39) |
Y200H |
probably damaging |
Het |
| H2-Eb1 |
T |
A |
17: 34,533,207 (GRCm39) |
V143D |
probably damaging |
Het |
| Ighv1-39 |
G |
A |
12: 114,878,488 (GRCm39) |
P28S |
probably benign |
Het |
| Inka1 |
C |
T |
9: 107,861,626 (GRCm39) |
R230H |
probably damaging |
Het |
| Iqgap1 |
C |
T |
7: 80,370,738 (GRCm39) |
V1544I |
probably benign |
Het |
| Itga10 |
A |
T |
3: 96,560,094 (GRCm39) |
Q536L |
probably benign |
Het |
| Itih2 |
C |
T |
2: 10,135,319 (GRCm39) |
E24K |
possibly damaging |
Het |
| Itsn2 |
A |
T |
12: 4,689,781 (GRCm39) |
N618I |
probably damaging |
Het |
| Kcnd2 |
T |
A |
6: 21,216,777 (GRCm39) |
S160R |
probably benign |
Het |
| Kif11 |
T |
A |
19: 37,398,204 (GRCm39) |
F677I |
probably damaging |
Het |
| Ldlrad2 |
C |
T |
4: 137,301,828 (GRCm39) |
C18Y |
probably damaging |
Het |
| Lrp4 |
T |
C |
2: 91,306,959 (GRCm39) |
V360A |
probably benign |
Het |
| Lrrtm2 |
T |
C |
18: 35,346,025 (GRCm39) |
T426A |
probably damaging |
Het |
| Mcidas |
T |
C |
13: 113,130,622 (GRCm39) |
F40L |
probably benign |
Het |
| Med27 |
T |
A |
2: 29,303,419 (GRCm39) |
L123Q |
possibly damaging |
Het |
| Mettl2 |
T |
C |
11: 105,023,364 (GRCm39) |
V249A |
probably benign |
Het |
| Mllt6 |
C |
A |
11: 97,565,426 (GRCm39) |
A592D |
probably benign |
Het |
| Mrps5 |
C |
T |
2: 127,442,804 (GRCm39) |
T291I |
probably damaging |
Het |
| Muc16 |
T |
A |
9: 18,553,016 (GRCm39) |
T4426S |
probably benign |
Het |
| Myh1 |
A |
T |
11: 67,099,715 (GRCm39) |
M542L |
probably benign |
Het |
| Nlrp12 |
G |
T |
7: 3,289,831 (GRCm39) |
A227D |
probably damaging |
Het |
| Nlrp14 |
T |
C |
7: 106,782,314 (GRCm39) |
Y504H |
probably damaging |
Het |
| Nr1i2 |
T |
C |
16: 38,086,442 (GRCm39) |
S8G |
probably benign |
Het |
| Ntrk2 |
A |
G |
13: 59,133,793 (GRCm39) |
K524R |
probably damaging |
Het |
| Nup210 |
C |
T |
6: 90,998,378 (GRCm39) |
|
probably null |
Het |
| Ogfr |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
GGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGG |
2: 180,237,059 (GRCm39) |
|
probably benign |
Het |
| Or4c100 |
T |
A |
2: 88,356,744 (GRCm39) |
Y272* |
probably null |
Het |
| Or52e4 |
T |
A |
7: 104,706,297 (GRCm39) |
Y281* |
probably null |
Het |
| Or5h27 |
A |
T |
16: 59,006,699 (GRCm39) |
I49N |
probably damaging |
Het |
| Patl1 |
A |
G |
19: 11,911,094 (GRCm39) |
I525M |
probably benign |
Het |
| Pcnx3 |
A |
G |
19: 5,723,364 (GRCm39) |
L1277P |
probably benign |
Het |
| Pelp1 |
G |
A |
11: 70,287,425 (GRCm39) |
T461I |
probably damaging |
Het |
| Phf20 |
T |
C |
2: 156,136,160 (GRCm39) |
C660R |
probably damaging |
Het |
| Pkd1l1 |
T |
A |
11: 8,851,203 (GRCm39) |
Y1193F |
|
Het |
| Pknox2 |
G |
T |
9: 36,868,364 (GRCm39) |
|
probably benign |
Het |
| Pml |
T |
C |
9: 58,137,177 (GRCm39) |
T541A |
probably benign |
Het |
| Prss35 |
C |
T |
9: 86,637,974 (GRCm39) |
T248I |
probably damaging |
Het |
| Rccd1 |
T |
A |
7: 79,970,350 (GRCm39) |
N89I |
probably benign |
Het |
| Rcor3 |
T |
C |
1: 191,821,824 (GRCm39) |
|
probably benign |
Het |
| Rreb1 |
A |
G |
13: 38,131,040 (GRCm39) |
E16G |
unknown |
Het |
| Scgb2b12 |
T |
A |
7: 32,026,060 (GRCm39) |
H44L |
probably benign |
Het |
| Sec23ip |
C |
T |
7: 128,346,727 (GRCm39) |
|
probably benign |
Het |
| Slc25a51 |
A |
T |
4: 45,399,841 (GRCm39) |
F116L |
possibly damaging |
Het |
| Spats2l |
T |
C |
1: 57,941,293 (GRCm39) |
V253A |
probably damaging |
Het |
| Spopl |
A |
T |
2: 23,427,521 (GRCm39) |
F204I |
probably benign |
Het |
| Sqle |
G |
A |
15: 59,202,603 (GRCm39) |
R519Q |
probably benign |
Het |
| Stil |
T |
G |
4: 114,881,233 (GRCm39) |
H592Q |
probably benign |
Het |
| Strip1 |
T |
A |
3: 107,533,046 (GRCm39) |
S201C |
probably damaging |
Het |
| Tcp11l1 |
C |
A |
2: 104,530,275 (GRCm39) |
A70S |
possibly damaging |
Het |
| Tmem163 |
T |
C |
1: 127,447,180 (GRCm39) |
|
probably null |
Het |
| Tmem184c |
A |
T |
8: 78,324,559 (GRCm39) |
Y310* |
probably null |
Het |
| Tmem30c |
T |
C |
16: 57,090,386 (GRCm39) |
N274D |
probably benign |
Het |
| Trim30c |
T |
A |
7: 104,039,397 (GRCm39) |
I133F |
probably damaging |
Het |
| Vars1 |
C |
T |
17: 35,223,768 (GRCm39) |
Q228* |
probably null |
Het |
| Zdbf2 |
G |
A |
1: 63,343,198 (GRCm39) |
V526I |
possibly damaging |
Het |
| Zfp819 |
T |
G |
7: 43,262,065 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Sgsm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00230:Sgsm1
|
APN |
5 |
113,392,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Sgsm1
|
APN |
5 |
113,424,008 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01377:Sgsm1
|
APN |
5 |
113,424,048 (GRCm39) |
splice site |
probably benign |
|
|
IGL01602:Sgsm1
|
APN |
5 |
113,433,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01605:Sgsm1
|
APN |
5 |
113,433,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01669:Sgsm1
|
APN |
5 |
113,411,356 (GRCm39) |
missense |
probably benign |
|
|
IGL01920:Sgsm1
|
APN |
5 |
113,421,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01951:Sgsm1
|
APN |
5 |
113,434,633 (GRCm39) |
splice site |
probably benign |
|
|
IGL02387:Sgsm1
|
APN |
5 |
113,400,929 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02690:Sgsm1
|
APN |
5 |
113,434,633 (GRCm39) |
splice site |
probably benign |
|
|
IGL03177:Sgsm1
|
APN |
5 |
113,398,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03186:Sgsm1
|
APN |
5 |
113,432,887 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03398:Sgsm1
|
APN |
5 |
113,403,182 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
caliente
|
UTSW |
5 |
113,428,328 (GRCm39) |
intron |
probably benign |
|
|
Chili
|
UTSW |
5 |
113,405,989 (GRCm39) |
intron |
probably benign |
|
|
pimiento
|
UTSW |
5 |
113,411,123 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0048:Sgsm1
|
UTSW |
5 |
113,416,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Sgsm1
|
UTSW |
5 |
113,432,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0058:Sgsm1
|
UTSW |
5 |
113,432,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Sgsm1
|
UTSW |
5 |
113,436,702 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0085:Sgsm1
|
UTSW |
5 |
113,427,136 (GRCm39) |
splice site |
probably benign |
|
|
R0099:Sgsm1
|
UTSW |
5 |
113,422,226 (GRCm39) |
splice site |
probably benign |
|
|
R0269:Sgsm1
|
UTSW |
5 |
113,434,795 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0310:Sgsm1
|
UTSW |
5 |
113,411,571 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0325:Sgsm1
|
UTSW |
5 |
113,436,701 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0420:Sgsm1
|
UTSW |
5 |
113,411,625 (GRCm39) |
missense |
probably benign |
0.16 |
|
R0594:Sgsm1
|
UTSW |
5 |
113,458,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0599:Sgsm1
|
UTSW |
5 |
113,392,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0631:Sgsm1
|
UTSW |
5 |
113,432,989 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Sgsm1
|
UTSW |
5 |
113,427,050 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0833:Sgsm1
|
UTSW |
5 |
113,427,050 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0919:Sgsm1
|
UTSW |
5 |
113,406,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0944:Sgsm1
|
UTSW |
5 |
113,413,740 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1169:Sgsm1
|
UTSW |
5 |
113,427,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1232:Sgsm1
|
UTSW |
5 |
113,421,577 (GRCm39) |
nonsense |
probably null |
|
|
R1473:Sgsm1
|
UTSW |
5 |
113,411,123 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1535:Sgsm1
|
UTSW |
5 |
113,411,135 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1796:Sgsm1
|
UTSW |
5 |
113,421,483 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1878:Sgsm1
|
UTSW |
5 |
113,411,381 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2084:Sgsm1
|
UTSW |
5 |
113,433,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Sgsm1
|
UTSW |
5 |
113,411,125 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3856:Sgsm1
|
UTSW |
5 |
113,411,125 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4294:Sgsm1
|
UTSW |
5 |
113,433,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4373:Sgsm1
|
UTSW |
5 |
113,405,989 (GRCm39) |
intron |
probably benign |
|
|
R4558:Sgsm1
|
UTSW |
5 |
113,405,977 (GRCm39) |
intron |
probably benign |
|
|
R4610:Sgsm1
|
UTSW |
5 |
113,403,173 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4667:Sgsm1
|
UTSW |
5 |
113,407,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4838:Sgsm1
|
UTSW |
5 |
113,430,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4890:Sgsm1
|
UTSW |
5 |
113,428,328 (GRCm39) |
intron |
probably benign |
|
|
R4992:Sgsm1
|
UTSW |
5 |
113,430,486 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5366:Sgsm1
|
UTSW |
5 |
113,398,905 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5776:Sgsm1
|
UTSW |
5 |
113,398,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Sgsm1
|
UTSW |
5 |
113,398,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6000:Sgsm1
|
UTSW |
5 |
113,434,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6354:Sgsm1
|
UTSW |
5 |
113,430,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6440:Sgsm1
|
UTSW |
5 |
113,426,997 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6831:Sgsm1
|
UTSW |
5 |
113,428,246 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7307:Sgsm1
|
UTSW |
5 |
113,421,512 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7309:Sgsm1
|
UTSW |
5 |
113,416,712 (GRCm39) |
splice site |
probably null |
|
|
R7439:Sgsm1
|
UTSW |
5 |
113,422,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7485:Sgsm1
|
UTSW |
5 |
113,427,501 (GRCm39) |
splice site |
probably null |
|
|
R7624:Sgsm1
|
UTSW |
5 |
113,422,201 (GRCm39) |
nonsense |
probably null |
|
|
R7632:Sgsm1
|
UTSW |
5 |
113,423,948 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7669:Sgsm1
|
UTSW |
5 |
113,400,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7727:Sgsm1
|
UTSW |
5 |
113,422,193 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7732:Sgsm1
|
UTSW |
5 |
113,414,196 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7961:Sgsm1
|
UTSW |
5 |
113,430,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8088:Sgsm1
|
UTSW |
5 |
113,403,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8213:Sgsm1
|
UTSW |
5 |
113,398,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8278:Sgsm1
|
UTSW |
5 |
113,407,958 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8480:Sgsm1
|
UTSW |
5 |
113,411,284 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8796:Sgsm1
|
UTSW |
5 |
113,411,123 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8816:Sgsm1
|
UTSW |
5 |
113,435,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8904:Sgsm1
|
UTSW |
5 |
113,421,495 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8905:Sgsm1
|
UTSW |
5 |
113,421,495 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8952:Sgsm1
|
UTSW |
5 |
113,432,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9046:Sgsm1
|
UTSW |
5 |
113,436,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9162:Sgsm1
|
UTSW |
5 |
113,430,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9249:Sgsm1
|
UTSW |
5 |
113,428,201 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9375:Sgsm1
|
UTSW |
5 |
113,422,139 (GRCm39) |
missense |
unknown |
|
|
R9377:Sgsm1
|
UTSW |
5 |
113,436,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9461:Sgsm1
|
UTSW |
5 |
113,423,898 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9662:Sgsm1
|
UTSW |
5 |
113,427,097 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9722:Sgsm1
|
UTSW |
5 |
113,428,207 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R9726:Sgsm1
|
UTSW |
5 |
113,458,418 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Sgsm1
|
UTSW |
5 |
113,430,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAGGAGGTCACTCTCAAGG -3'
(R):5'- GCCATGAGCTATGTTGCCATG -3'
Sequencing Primer
(F):5'- AGGAGGTCACTCTCAAGGCTATC -3'
(R):5'- ATGTTGCCATGCGAGTCC -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation