Mutagenetix > Incidental Mutation

Incidental Mutation 'R7426:Fsip2'

576040

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

045504-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

R7426 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

82773978-82839281 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 82810441 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Phenylalanine at position 2253 (L2253F)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000143764
AA Change: L2253F

PolyPhen 2 Score 0.976 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: L2253F

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.0%

Validation Efficiency

97% (114/118)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 117 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca15	C	A	7: 119,945,221 (GRCm39)	N432K	possibly damaging	Het
Abitram	A	G	4: 56,804,230 (GRCm39)	I82V	probably null	Het
Adamtsl5	G	A	10: 80,180,693 (GRCm39)	T123I	probably benign	Het
Aff4	T	C	11: 53,263,702 (GRCm39)	S241P	probably damaging	Het
Agl	A	G	3: 116,552,404 (GRCm39)	L510P		Het
Aox1	A	T	1: 58,329,142 (GRCm39)	K196*	probably null	Het
Arhgef37	A	G	18: 61,637,456 (GRCm39)	L402P	probably damaging	Het
Arid4b	T	C	13: 14,355,891 (GRCm39)		probably null	Het
Atp5pb	A	G	3: 105,851,118 (GRCm39)	V193A	probably benign	Het
Atp8b3	A	G	10: 80,365,463 (GRCm39)		probably null	Het
Baz2a	G	T	10: 127,951,947 (GRCm39)	R555L	probably damaging	Het
Casp4	G	T	9: 5,321,345 (GRCm39)	S32I	possibly damaging	Het
Cd300lb	A	G	11: 114,819,128 (GRCm39)	V167A	probably damaging	Het
Cdc42bpg	C	T	19: 6,368,428 (GRCm39)	T1042I	probably damaging	Het
Ceacam20	T	C	7: 19,704,159 (GRCm39)	F70S	probably damaging	Het
Cep162	C	T	9: 87,074,819 (GRCm39)	V1388I	probably damaging	Het
Cfap65	A	G	1: 74,959,585 (GRCm39)	V855A	possibly damaging	Het
Chil3	G	T	3: 106,063,022 (GRCm39)	D189E	probably benign	Het
Cln3	A	G	7: 126,180,912 (GRCm39)	I43T	probably benign	Het
Cntnap5a	A	G	1: 116,370,110 (GRCm39)	Q909R	probably benign	Het
Ctsd	C	A	7: 141,937,278 (GRCm39)	A77S	probably damaging	Het
Dnah12	T	A	14: 26,445,781 (GRCm39)	S781T	probably benign	Het
Dnah17	T	A	11: 117,981,543 (GRCm39)	Q1716L	probably null	Het
Dock3	C	A	9: 106,772,782 (GRCm39)	M490I	probably benign	Het
Erg	T	C	16: 95,260,015 (GRCm39)		probably null	Het
Farp2	A	T	1: 93,548,950 (GRCm39)	M1019L	possibly damaging	Het
Fcgbp	A	G	7: 27,785,949 (GRCm39)	K462R	probably benign	Het
Fn1	A	T	1: 71,688,384 (GRCm39)	N173K	probably damaging	Het
Gabrd	C	T	4: 155,469,970 (GRCm39)	R413H	possibly damaging	Het
Galnt5	A	T	2: 57,907,151 (GRCm39)	D538V	probably damaging	Het
Gje1	T	A	10: 14,592,223 (GRCm39)	L186F	probably damaging	Het
Gm16686	A	T	4: 88,673,563 (GRCm39)	C89S	unknown	Het
Gna15	G	T	10: 81,338,831 (GRCm39)	A336E	probably benign	Het
Golga4	C	T	9: 118,388,563 (GRCm39)	S1895L	probably benign	Het
Gon4l	A	T	3: 88,814,829 (GRCm39)	M1933L	probably benign	Het
Gpr183	T	C	14: 122,192,156 (GRCm39)	S122G	possibly damaging	Het
Gtf2h4	G	A	17: 35,980,250 (GRCm39)	T348I	probably damaging	Het
Hace1	T	C	10: 45,481,636 (GRCm39)	Y120H	probably damaging	Het
Hivep2	C	T	10: 14,007,061 (GRCm39)	H1220Y	possibly damaging	Het
Hmx2	T	C	7: 131,156,232 (GRCm39)	F66S	probably benign	Het
Hoxd12	A	T	2: 74,505,569 (GRCm39)	S47C	possibly damaging	Het
Hp	C	A	8: 110,301,832 (GRCm39)		probably null	Het
Idh3a	T	A	9: 54,508,492 (GRCm39)	D355E	probably benign	Het
Itga2b	A	T	11: 102,347,120 (GRCm39)	M921K	probably benign	Het
Jcad	A	G	18: 4,675,529 (GRCm39)	D1097G	probably benign	Het
Kdm5b	A	T	1: 134,523,571 (GRCm39)	T249S	probably benign	Het
Klhl11	G	T	11: 100,355,178 (GRCm39)	H214Q	probably benign	Het
L3hypdh	A	T	12: 72,131,705 (GRCm39)	Y76N	probably damaging	Het
Lama4	G	T	10: 38,921,751 (GRCm39)	R424L	possibly damaging	Het
Lepr	A	G	4: 101,602,853 (GRCm39)	I214V	probably benign	Het
Lipc	G	T	9: 70,709,450 (GRCm39)	N432K	probably benign	Het
Lipm	C	T	19: 34,093,598 (GRCm39)	A216V	possibly damaging	Het
Lrrc23	A	G	6: 124,756,088 (GRCm39)	S2P	unknown	Het
Lyst	T	A	13: 13,812,109 (GRCm39)	D840E	probably benign	Het
Mmp23	T	A	4: 155,736,041 (GRCm39)	T204S	probably damaging	Het
Mms19	T	C	19: 41,936,717 (GRCm39)	T785A	probably benign	Het
Mov10	A	T	3: 104,707,368 (GRCm39)		probably null	Het
Mtf2	A	G	5: 108,248,836 (GRCm39)	T383A	probably benign	Het
Myo5c	G	A	9: 75,158,809 (GRCm39)		probably null	Het
Nfxl1	A	T	5: 72,681,517 (GRCm39)	C671*	probably null	Het
Npepps	A	G	11: 97,103,982 (GRCm39)	V813A	probably benign	Het
Nrn1	C	A	13: 36,910,825 (GRCm39)	W69L	probably damaging	Het
Oprd1	A	C	4: 131,841,378 (GRCm39)	D193E	probably benign	Het
Or2ag1b	T	A	7: 106,288,417 (GRCm39)	I174F	possibly damaging	Het
Or52p1	C	T	7: 104,267,059 (GRCm39)	H58Y	probably damaging	Het
Or55b3	A	T	7: 102,126,883 (GRCm39)	Y65N	probably damaging	Het
Or56b2j	T	A	7: 104,352,796 (GRCm39)	D7E	probably benign	Het
Or6c202	A	G	10: 128,996,620 (GRCm39)	Y78H	possibly damaging	Het
Or6c209	T	C	10: 129,483,027 (GRCm39)	I10T	probably damaging	Het
Or6k6	A	C	1: 173,944,753 (GRCm39)	F276L	probably benign	Het
Pcdhac1	G	T	18: 37,225,550 (GRCm39)	V788L	probably benign	Het
Pcdhb11	G	A	18: 37,556,313 (GRCm39)	V548M	probably damaging	Het
Pde4c	A	T	8: 71,201,621 (GRCm39)	E517V	possibly damaging	Het
Pdzd7	T	C	19: 45,022,086 (GRCm39)	R521G	possibly damaging	Het
Pik3c2a	T	A	7: 115,972,089 (GRCm39)	K780N	probably damaging	Het
Plb1	T	G	5: 32,478,591 (GRCm39)		probably null	Het
Plcb4	T	A	2: 135,842,139 (GRCm39)	L1041Q	probably benign	Het
Pnpla6	G	A	8: 3,566,540 (GRCm39)		probably null	Het
Ppat	A	T	5: 77,063,826 (GRCm39)	N441K	probably damaging	Het
Ppp1r1b	G	A	11: 98,246,305 (GRCm39)	A132T	probably damaging	Het
Prl2c2	A	C	13: 13,172,065 (GRCm39)		probably null	Het
Prr14	T	C	7: 127,074,458 (GRCm39)	I330T	probably benign	Het
Pycr1	T	C	11: 120,533,749 (GRCm39)	D36G	probably benign	Het
Rabep2	T	A	7: 126,037,891 (GRCm39)	I221N	probably damaging	Het
Rad23b	A	G	4: 55,370,469 (GRCm39)	D165G	probably benign	Het
Reln	G	A	5: 22,176,951 (GRCm39)	T1905I	probably damaging	Het
Ripor2	T	C	13: 24,878,188 (GRCm39)	V321A	probably benign	Het
Rnf43	A	G	11: 87,622,678 (GRCm39)	D466G	probably benign	Het
Rpl6	A	T	5: 121,343,655 (GRCm39)	R63W	possibly damaging	Het
S100a14	A	G	3: 90,435,511 (GRCm39)	T102A	probably benign	Het
Samd11	C	A	4: 156,333,857 (GRCm39)	V195L	probably benign	Het
Scaper	G	A	9: 55,669,561 (GRCm39)	Q372*	probably null	Het
Sec14l5	G	T	16: 4,998,739 (GRCm39)	C593F	probably damaging	Het
Sema6d	T	C	2: 124,496,078 (GRCm39)	Y41H	probably damaging	Het
Serac1	G	A	17: 6,119,589 (GRCm39)	R114W	probably damaging	Het
Slc12a4	T	C	8: 106,677,468 (GRCm39)	E388G	probably benign	Het
Smarcd3	T	C	5: 24,800,810 (GRCm39)	T164A	probably benign	Het
Smtn	C	A	11: 3,480,249 (GRCm39)	R324L	probably benign	Het
Spata31d1c	C	T	13: 65,183,175 (GRCm39)	P239L	probably benign	Het
Srcap	T	C	7: 127,137,689 (GRCm39)	V1013A	possibly damaging	Het
Sv2b	T	C	7: 74,773,812 (GRCm39)	N553S	probably damaging	Het
Tex35	T	A	1: 156,932,656 (GRCm39)	N52I	probably damaging	Het
Ticrr	T	C	7: 79,343,734 (GRCm39)	S1200P	probably benign	Het
Tmem19	A	G	10: 115,183,604 (GRCm39)	L125P	probably damaging	Het
Trio	A	G	15: 27,856,193 (GRCm39)	V666A	probably benign	Het
Ttn	T	C	2: 76,747,627 (GRCm39)	D4474G	probably benign	Het
Usp43	A	T	11: 67,783,842 (GRCm39)	S368T	possibly damaging	Het
Vmn2r72	T	A	7: 85,400,348 (GRCm39)	M234L	probably benign	Het
Wdr93	T	A	7: 79,427,055 (GRCm39)		probably null	Het
Wrap73	T	A	4: 154,240,584 (GRCm39)	W359R	probably damaging	Het
Ywhah	A	G	5: 33,183,985 (GRCm39)	I63V	probably benign	Het
Zbtb7b	G	T	3: 89,288,366 (GRCm39)	P151T	probably damaging	Het
Zfp318	A	G	17: 46,710,995 (GRCm39)	N906S	probably damaging	Het
Zfp423	C	A	8: 88,507,341 (GRCm39)	C1001F	probably damaging	Het
Zmym1	A	G	4: 126,943,191 (GRCm39)	I399T	possibly damaging	Het
Zmynd15	G	A	11: 70,353,014 (GRCm39)	G296D	probably benign	Het
Znfx1	T	A	2: 166,890,475 (GRCm39)	I670F	probably damaging	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,820,730 (GRCm39)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,821,657 (GRCm39)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,830,163 (GRCm39)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,823,326 (GRCm39)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,807,863 (GRCm39)	missense	probably benign
IGL01554:Fsip2	APN	2	82,807,622 (GRCm39)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,821,430 (GRCm39)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,808,691 (GRCm39)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,812,983 (GRCm39)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,815,273 (GRCm39)	missense	probably benign
IGL01918:Fsip2	APN	2	82,822,482 (GRCm39)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,824,349 (GRCm39)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,824,211 (GRCm39)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,822,204 (GRCm39)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,809,065 (GRCm39)	missense	probably benign
IGL02155:Fsip2	APN	2	82,828,696 (GRCm39)	missense	probably benign
IGL02219:Fsip2	APN	2	82,808,174 (GRCm39)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,813,116 (GRCm39)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,809,137 (GRCm39)	missense	probably benign
IGL02478:Fsip2	APN	2	82,814,736 (GRCm39)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,809,199 (GRCm39)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,822,347 (GRCm39)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,779,836 (GRCm39)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,823,407 (GRCm39)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,828,662 (GRCm39)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,812,501 (GRCm39)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,781,370 (GRCm39)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,823,839 (GRCm39)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,822,701 (GRCm39)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,813,398 (GRCm39)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,820,968 (GRCm39)	intron	probably benign
IGL03076:Fsip2	APN	2	82,812,482 (GRCm39)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,808,420 (GRCm39)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,807,737 (GRCm39)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,820,814 (GRCm39)	missense	probably benign
bubblegum	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
Dao	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
engulf	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
envelope	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
gladius	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
glove	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
Katana	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
scarf	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
Sock	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
swaddle	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
wrap	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
Wrapper	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,818,756 (GRCm39)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,814,709 (GRCm39)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,814,706 (GRCm39)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,821,196 (GRCm39)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,830,201 (GRCm39)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,806,952 (GRCm39)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,815,269 (GRCm39)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,821,465 (GRCm39)	missense	probably benign
R0149:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,811,151 (GRCm39)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,815,521 (GRCm39)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,816,240 (GRCm39)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,813,677 (GRCm39)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,814,908 (GRCm39)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,821,419 (GRCm39)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,808,129 (GRCm39)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,777,296 (GRCm39)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,824,139 (GRCm39)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,807,877 (GRCm39)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,774,484 (GRCm39)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,819,302 (GRCm39)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,807,241 (GRCm39)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,816,513 (GRCm39)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,821,703 (GRCm39)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,812,683 (GRCm39)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,816,617 (GRCm39)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,815,828 (GRCm39)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,828,375 (GRCm39)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,819,780 (GRCm39)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,818,805 (GRCm39)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,805,378 (GRCm39)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,821,844 (GRCm39)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,805,570 (GRCm39)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,805,361 (GRCm39)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,811,355 (GRCm39)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,820,107 (GRCm39)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,819,752 (GRCm39)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,820,089 (GRCm39)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,828,407 (GRCm39)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,817,539 (GRCm39)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,810,155 (GRCm39)	missense	probably benign
R1520:Fsip2	UTSW	2	82,811,058 (GRCm39)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,811,931 (GRCm39)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,816,626 (GRCm39)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,808,861 (GRCm39)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,816,689 (GRCm39)	missense	probably benign
R1700:Fsip2	UTSW	2	82,822,081 (GRCm39)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,805,289 (GRCm39)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,820,256 (GRCm39)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,818,055 (GRCm39)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,815,240 (GRCm39)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,830,185 (GRCm39)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,807,906 (GRCm39)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,814,933 (GRCm39)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,823,601 (GRCm39)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,811,127 (GRCm39)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,817,077 (GRCm39)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,810,902 (GRCm39)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,821,894 (GRCm39)	missense	probably benign
R1965:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,810,175 (GRCm39)	missense	probably benign
R1988:Fsip2	UTSW	2	82,806,861 (GRCm39)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,819,788 (GRCm39)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,808,856 (GRCm39)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,806,699 (GRCm39)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	82,839,159 (GRCm39)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,818,923 (GRCm39)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,820,615 (GRCm39)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,807,823 (GRCm39)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,793,095 (GRCm39)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,805,437 (GRCm39)	missense	probably benign
R2344:Fsip2	UTSW	2	82,820,257 (GRCm39)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,806,593 (GRCm39)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,811,064 (GRCm39)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,815,685 (GRCm39)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,809,954 (GRCm39)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,782,001 (GRCm39)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,808,511 (GRCm39)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,820,775 (GRCm39)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,809,389 (GRCm39)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,821,868 (GRCm39)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,816,854 (GRCm39)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,822,354 (GRCm39)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,817,071 (GRCm39)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,815,253 (GRCm39)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,819,311 (GRCm39)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,808,561 (GRCm39)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,813,058 (GRCm39)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,781,290 (GRCm39)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,819,950 (GRCm39)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,816,759 (GRCm39)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,789,006 (GRCm39)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,813,862 (GRCm39)	missense	probably benign
R4042:Fsip2	UTSW	2	82,813,896 (GRCm39)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,813,245 (GRCm39)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,817,413 (GRCm39)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,808,201 (GRCm39)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,821,550 (GRCm39)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,782,009 (GRCm39)	missense	probably benign
R4549:Fsip2	UTSW	2	82,819,972 (GRCm39)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,815,297 (GRCm39)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,816,510 (GRCm39)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,809,017 (GRCm39)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,818,103 (GRCm39)	missense	probably benign
R4700:Fsip2	UTSW	2	82,817,373 (GRCm39)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,805,203 (GRCm39)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,805,697 (GRCm39)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,819,629 (GRCm39)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,812,452 (GRCm39)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,818,044 (GRCm39)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,818,786 (GRCm39)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,820,515 (GRCm39)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,815,815 (GRCm39)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,779,739 (GRCm39)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,821,295 (GRCm39)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,805,202 (GRCm39)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,818,438 (GRCm39)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,811,837 (GRCm39)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,824,114 (GRCm39)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,815,384 (GRCm39)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,807,758 (GRCm39)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,777,276 (GRCm39)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,816,222 (GRCm39)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,809,773 (GRCm39)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,819,477 (GRCm39)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,818,836 (GRCm39)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,821,460 (GRCm39)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,822,329 (GRCm39)	missense	probably benign
R5119:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,811,768 (GRCm39)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,808,916 (GRCm39)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,813,338 (GRCm39)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,823,505 (GRCm39)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,808,925 (GRCm39)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,818,489 (GRCm39)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,820,185 (GRCm39)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,805,742 (GRCm39)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,821,262 (GRCm39)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,812,572 (GRCm39)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,810,230 (GRCm39)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,815,654 (GRCm39)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,815,542 (GRCm39)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,781,256 (GRCm39)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,781,252 (GRCm39)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,793,090 (GRCm39)	missense	probably benign
R5568:Fsip2	UTSW	2	82,816,908 (GRCm39)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,828,472 (GRCm39)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,818,439 (GRCm39)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,817,838 (GRCm39)	nonsense	probably null
R5712:Fsip2	UTSW	2	82,839,192 (GRCm39)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,808,260 (GRCm39)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,815,084 (GRCm39)	missense	probably benign
R5881:Fsip2	UTSW	2	82,814,785 (GRCm39)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,822,953 (GRCm39)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,818,852 (GRCm39)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,817,092 (GRCm39)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,807,835 (GRCm39)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,793,657 (GRCm39)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,820,812 (GRCm39)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,818,283 (GRCm39)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,822,471 (GRCm39)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,816,017 (GRCm39)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,809,777 (GRCm39)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,821,388 (GRCm39)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,824,112 (GRCm39)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,818,289 (GRCm39)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,817,601 (GRCm39)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,811,071 (GRCm39)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,812,798 (GRCm39)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,820,227 (GRCm39)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,810,785 (GRCm39)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,819,242 (GRCm39)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,823,416 (GRCm39)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,823,028 (GRCm39)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,813,836 (GRCm39)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,812,657 (GRCm39)	missense	probably benign
R6621:Fsip2	UTSW	2	82,820,158 (GRCm39)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,813,571 (GRCm39)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,798,161 (GRCm39)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,809,878 (GRCm39)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,816,776 (GRCm39)	missense	probably benign
R6790:Fsip2	UTSW	2	82,821,283 (GRCm39)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,811,303 (GRCm39)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,815,544 (GRCm39)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,813,969 (GRCm39)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,816,332 (GRCm39)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,809,061 (GRCm39)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,778,630 (GRCm39)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,807,298 (GRCm39)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,817,269 (GRCm39)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,820,979 (GRCm39)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,821,235 (GRCm39)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,811,078 (GRCm39)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,813,496 (GRCm39)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,817,968 (GRCm39)	missense	probably benign
R7126:Fsip2	UTSW	2	82,813,485 (GRCm39)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,813,085 (GRCm39)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,811,541 (GRCm39)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,816,571 (GRCm39)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,823,581 (GRCm39)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,819,412 (GRCm39)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,814,015 (GRCm39)	missense	probably benign
R7228:Fsip2	UTSW	2	82,822,651 (GRCm39)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,812,484 (GRCm39)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,823,607 (GRCm39)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,809,425 (GRCm39)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,812,474 (GRCm39)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,810,863 (GRCm39)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,820,035 (GRCm39)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,813,462 (GRCm39)	missense	probably benign
R7343:Fsip2	UTSW	2	82,809,711 (GRCm39)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,819,140 (GRCm39)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,820,663 (GRCm39)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,815,601 (GRCm39)	missense	possibly damaging	0.53
R7450:Fsip2	UTSW	2	82,782,024 (GRCm39)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,818,894 (GRCm39)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,815,196 (GRCm39)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,824,337 (GRCm39)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,819,361 (GRCm39)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,805,585 (GRCm39)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,817,256 (GRCm39)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,812,149 (GRCm39)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,820,455 (GRCm39)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,811,252 (GRCm39)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,818,723 (GRCm39)	missense	probably benign
R7811:Fsip2	UTSW	2	82,828,797 (GRCm39)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,807,044 (GRCm39)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,808,168 (GRCm39)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,781,365 (GRCm39)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,816,120 (GRCm39)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,818,793 (GRCm39)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
R8034:Fsip2	UTSW	2	82,819,699 (GRCm39)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,816,322 (GRCm39)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,789,017 (GRCm39)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,823,296 (GRCm39)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,806,141 (GRCm39)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,818,021 (GRCm39)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,815,088 (GRCm39)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,806,951 (GRCm39)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,820,808 (GRCm39)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,808,487 (GRCm39)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,811,346 (GRCm39)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,818,724 (GRCm39)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,821,099 (GRCm39)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,818,198 (GRCm39)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,822,239 (GRCm39)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8419:Fsip2	UTSW	2	82,808,963 (GRCm39)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,811,910 (GRCm39)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,807,430 (GRCm39)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8459:Fsip2	UTSW	2	82,810,022 (GRCm39)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,810,284 (GRCm39)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,777,336 (GRCm39)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,821,871 (GRCm39)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,815,246 (GRCm39)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,811,453 (GRCm39)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,815,822 (GRCm39)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,813,453 (GRCm39)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,821,606 (GRCm39)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,820,782 (GRCm39)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,809,524 (GRCm39)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,807,681 (GRCm39)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,816,984 (GRCm39)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,810,938 (GRCm39)	missense	probably benign
R8926:Fsip2	UTSW	2	82,823,927 (GRCm39)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,815,370 (GRCm39)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,806,898 (GRCm39)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,817,075 (GRCm39)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,828,545 (GRCm39)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,806,180 (GRCm39)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,807,301 (GRCm39)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,816,103 (GRCm39)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,813,170 (GRCm39)	missense	probably benign
R9149:Fsip2	UTSW	2	82,812,374 (GRCm39)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,815,574 (GRCm39)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,817,844 (GRCm39)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,820,425 (GRCm39)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,823,062 (GRCm39)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,815,958 (GRCm39)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,807,662 (GRCm39)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,818,604 (GRCm39)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,818,747 (GRCm39)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,811,039 (GRCm39)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,822,756 (GRCm39)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,819,793 (GRCm39)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,805,907 (GRCm39)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,816,702 (GRCm39)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,806,132 (GRCm39)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,817,285 (GRCm39)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,793,062 (GRCm39)	missense	probably benign
R9523:Fsip2	UTSW	2	82,807,972 (GRCm39)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,798,173 (GRCm39)	missense	probably benign
R9636:Fsip2	UTSW	2	82,820,563 (GRCm39)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,821,984 (GRCm39)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,819,272 (GRCm39)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,806,226 (GRCm39)	missense	probably benign
R9705:Fsip2	UTSW	2	82,823,634 (GRCm39)	missense	probably benign
R9739:Fsip2	UTSW	2	82,823,896 (GRCm39)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,818,241 (GRCm39)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,821,994 (GRCm39)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,810,225 (GRCm39)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,821,865 (GRCm39)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,822,876 (GRCm39)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,808,184 (GRCm39)	missense	probably benign
RF028:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,812,851 (GRCm39)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,781,364 (GRCm39)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,785,290 (GRCm39)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,807,122 (GRCm39)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,817,807 (GRCm39)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,818,978 (GRCm39)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,817,997 (GRCm39)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,805,792 (GRCm39)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,820,009 (GRCm39)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,814,868 (GRCm39)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,777,304 (GRCm39)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,817,547 (GRCm39)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- GCAAGAGTGGCCATCTATGAC -3'
(R):5'- TGGGTTCTACAAGCTCTTGG -3'

Sequencing Primer
(F):5'- AGAGTGGCCATCTATGACATTTTTCC -3'
(R):5'- GCTCTTGGCTAGTAACTGTTCTAG -3'

Posted On

2019-10-07