Incidental Mutation 'R8079:Ablim1'
| ID |
629255 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ablim1
|
| Ensembl Gene |
ENSMUSG00000025085 |
| Gene Name |
actin-binding LIM protein 1 |
| Synonyms |
4833406P10Rik, 9330196J19Rik, 2610209L21Rik, Limab1, 2210411C18Rik, abLIM-S, abLIM-M, abLIM-L |
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.355)
|
| Stock # |
R8079 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
19 |
| Chromosomal Location |
57021165-57303351 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to T
at 57170656 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000079360]
[ENSMUST00000099294]
[ENSMUST00000111524]
[ENSMUST00000111544]
[ENSMUST00000111546]
[ENSMUST00000111550]
[ENSMUST00000111555]
[ENSMUST00000111558]
[ENSMUST00000111559]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000079360
|
| SMART Domains |
Protein: ENSMUSP00000078336
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
16 |
N/A |
INTRINSIC |
|
LIM
|
98 |
149 |
1.14e-9 |
SMART |
|
LIM
|
157 |
209 |
1.37e-12 |
SMART |
|
LIM
|
225 |
276 |
1.12e-17 |
SMART |
|
LIM
|
284 |
336 |
5.87e-12 |
SMART |
|
Pfam:AbLIM_anchor
|
393 |
825 |
1.9e-139 |
PFAM |
|
VHP
|
826 |
861 |
1.22e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099294
|
| SMART Domains |
Protein: ENSMUSP00000096897
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
22 |
73 |
1.14e-9 |
SMART |
|
LIM
|
81 |
133 |
1.37e-12 |
SMART |
|
LIM
|
149 |
200 |
1.12e-17 |
SMART |
|
LIM
|
208 |
260 |
5.87e-12 |
SMART |
|
low complexity region
|
284 |
293 |
N/A |
INTRINSIC |
|
coiled coil region
|
467 |
491 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
531 |
N/A |
INTRINSIC |
|
VHP
|
619 |
654 |
1.22e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111524
|
| SMART Domains |
Protein: ENSMUSP00000107149
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
21 |
72 |
1.14e-9 |
SMART |
|
LIM
|
80 |
132 |
1.37e-12 |
SMART |
|
LIM
|
148 |
199 |
1.12e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111544
|
| SMART Domains |
Protein: ENSMUSP00000107169
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
22 |
73 |
1.14e-9 |
SMART |
|
LIM
|
81 |
133 |
1.37e-12 |
SMART |
|
LIM
|
149 |
200 |
1.12e-17 |
SMART |
|
LIM
|
208 |
260 |
5.87e-12 |
SMART |
|
low complexity region
|
284 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
427 |
N/A |
INTRINSIC |
|
coiled coil region
|
481 |
505 |
N/A |
INTRINSIC |
|
low complexity region
|
530 |
545 |
N/A |
INTRINSIC |
|
VHP
|
633 |
668 |
1.22e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111546
|
| SMART Domains |
Protein: ENSMUSP00000107172
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
22 |
73 |
5.7e-12 |
SMART |
|
LIM
|
81 |
133 |
6.6e-15 |
SMART |
|
LIM
|
149 |
200 |
5.4e-20 |
SMART |
|
LIM
|
208 |
260 |
2.8e-14 |
SMART |
|
low complexity region
|
284 |
293 |
N/A |
INTRINSIC |
|
coiled coil region
|
514 |
538 |
N/A |
INTRINSIC |
|
low complexity region
|
563 |
578 |
N/A |
INTRINSIC |
|
VHP
|
666 |
700 |
1.2e-15 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111550
|
| SMART Domains |
Protein: ENSMUSP00000107175
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
22 |
73 |
1.14e-9 |
SMART |
|
LIM
|
81 |
133 |
1.37e-12 |
SMART |
|
LIM
|
149 |
200 |
1.12e-17 |
SMART |
|
LIM
|
208 |
260 |
5.87e-12 |
SMART |
|
low complexity region
|
312 |
321 |
N/A |
INTRINSIC |
|
coiled coil region
|
495 |
519 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
VHP
|
647 |
682 |
1.22e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111555
|
| SMART Domains |
Protein: ENSMUSP00000107180
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
16 |
N/A |
INTRINSIC |
|
LIM
|
98 |
149 |
1.14e-9 |
SMART |
|
LIM
|
157 |
209 |
1.37e-12 |
SMART |
|
LIM
|
225 |
276 |
1.12e-17 |
SMART |
|
LIM
|
284 |
336 |
5.87e-12 |
SMART |
|
low complexity region
|
360 |
369 |
N/A |
INTRINSIC |
|
coiled coil region
|
590 |
614 |
N/A |
INTRINSIC |
|
low complexity region
|
639 |
654 |
N/A |
INTRINSIC |
|
VHP
|
742 |
777 |
1.22e-17 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000133369
|
| SMART Domains |
Protein: ENSMUSP00000117798
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
45 |
96 |
1.14e-9 |
SMART |
|
LIM
|
104 |
156 |
1.37e-12 |
SMART |
|
LIM
|
172 |
223 |
1.12e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111558
|
| SMART Domains |
Protein: ENSMUSP00000107183
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
35 |
86 |
1.14e-9 |
SMART |
|
LIM
|
94 |
146 |
1.37e-12 |
SMART |
|
LIM
|
162 |
213 |
1.12e-17 |
SMART |
|
LIM
|
221 |
273 |
5.87e-12 |
SMART |
|
low complexity region
|
325 |
334 |
N/A |
INTRINSIC |
|
low complexity region
|
498 |
503 |
N/A |
INTRINSIC |
|
coiled coil region
|
557 |
581 |
N/A |
INTRINSIC |
|
low complexity region
|
606 |
621 |
N/A |
INTRINSIC |
|
VHP
|
709 |
744 |
1.22e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111559
|
| SMART Domains |
Protein: ENSMUSP00000107184
Gene: ENSMUSG00000025085
| Domain | Start | End | E-Value | Type |
|---|
|
LIM
|
35 |
86 |
1.14e-9 |
SMART |
|
LIM
|
94 |
146 |
1.37e-12 |
SMART |
|
LIM
|
162 |
213 |
1.12e-17 |
SMART |
|
LIM
|
221 |
273 |
5.87e-12 |
SMART |
|
low complexity region
|
297 |
306 |
N/A |
INTRINSIC |
|
coiled coil region
|
527 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
576 |
591 |
N/A |
INTRINSIC |
|
VHP
|
679 |
714 |
1.22e-17 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 99.0%
- 20x: 96.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mutant mice lacking the retina-specific isoform are healthy, fertile, and show no defects in retinal development or retinofugal projections. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(6) : Targeted, knock-out(1) Targeted, other(1) Gene trapped(4) |
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb9 |
A |
G |
5: 124,221,186 (GRCm39) |
I255T |
possibly damaging |
Het |
| Akap10 |
G |
A |
11: 61,820,880 (GRCm39) |
P8L |
possibly damaging |
Het |
| Ankle2 |
C |
T |
5: 110,379,182 (GRCm39) |
A27V |
probably damaging |
Het |
| Anxa8 |
A |
G |
14: 33,816,769 (GRCm39) |
T246A |
probably benign |
Het |
| Arhgap5 |
A |
G |
12: 52,613,988 (GRCm39) |
N1460S |
probably benign |
Het |
| Arid5b |
T |
G |
10: 67,934,186 (GRCm39) |
D572A |
possibly damaging |
Het |
| Atrn |
T |
A |
2: 130,855,561 (GRCm39) |
L1278Q |
probably null |
Het |
| AU040320 |
G |
T |
4: 126,725,953 (GRCm39) |
K454N |
possibly damaging |
Het |
| Baz2b |
T |
A |
2: 59,731,112 (GRCm39) |
R2085W |
probably damaging |
Het |
| Bbx |
A |
T |
16: 50,030,821 (GRCm39) |
N649K |
probably damaging |
Het |
| BC034090 |
G |
A |
1: 155,101,032 (GRCm39) |
P411S |
probably damaging |
Het |
| Calcoco2 |
A |
T |
11: 95,998,363 (GRCm39) |
F20Y |
probably damaging |
Het |
| Carmil2 |
A |
G |
8: 106,413,393 (GRCm39) |
R50G |
probably damaging |
Het |
| Catspere2 |
A |
G |
1: 177,874,525 (GRCm39) |
T131A |
probably benign |
Het |
| Cdcp1 |
C |
A |
9: 123,002,855 (GRCm39) |
V739L |
probably damaging |
Het |
| Chit1 |
A |
G |
1: 134,071,765 (GRCm39) |
T92A |
possibly damaging |
Het |
| Clstn3 |
A |
G |
6: 124,436,763 (GRCm39) |
I185T |
probably damaging |
Het |
| Dctpp1 |
C |
A |
7: 126,858,561 (GRCm39) |
V61L |
probably damaging |
Het |
| Dip2a |
T |
C |
10: 76,123,155 (GRCm39) |
T760A |
probably benign |
Het |
| Dock10 |
C |
T |
1: 80,556,421 (GRCm39) |
V552I |
probably benign |
Het |
| Dpp8 |
A |
G |
9: 64,951,017 (GRCm39) |
E151G |
probably damaging |
Het |
| Dvl2 |
G |
C |
11: 69,898,344 (GRCm39) |
R367P |
possibly damaging |
Het |
| Fem1b |
A |
T |
9: 62,703,643 (GRCm39) |
I539N |
probably damaging |
Het |
| Frat2 |
A |
T |
19: 41,836,277 (GRCm39) |
L25H |
probably damaging |
Het |
| Garnl3 |
A |
T |
2: 32,908,511 (GRCm39) |
|
probably null |
Het |
| Gh |
T |
C |
11: 106,192,253 (GRCm39) |
H47R |
possibly damaging |
Het |
| Glmp |
T |
C |
3: 88,233,045 (GRCm39) |
V61A |
probably damaging |
Het |
| Gm9925 |
T |
C |
18: 74,198,558 (GRCm39) |
V129A |
unknown |
Het |
| H2-M9 |
T |
A |
17: 36,953,025 (GRCm39) |
E94V |
probably benign |
Het |
| Hira |
A |
T |
16: 18,744,507 (GRCm39) |
Q408L |
probably benign |
Het |
| Hook3 |
A |
G |
8: 26,578,086 (GRCm39) |
|
probably null |
Het |
| Ifi206 |
G |
A |
1: 173,308,724 (GRCm39) |
P424L |
|
Het |
| Impdh2 |
T |
C |
9: 108,440,524 (GRCm39) |
V270A |
probably benign |
Het |
| Klhl14 |
A |
G |
18: 21,785,022 (GRCm39) |
I135T |
probably benign |
Het |
| Klra10 |
C |
A |
6: 130,252,738 (GRCm39) |
V179L |
probably benign |
Het |
| Kmt2c |
T |
C |
5: 25,507,730 (GRCm39) |
S3236G |
probably damaging |
Het |
| Krt76 |
G |
T |
15: 101,796,825 (GRCm39) |
A358D |
possibly damaging |
Het |
| Lacc1 |
C |
A |
14: 77,266,992 (GRCm39) |
G424C |
probably damaging |
Het |
| Limch1 |
A |
G |
5: 67,204,096 (GRCm39) |
I878V |
possibly damaging |
Het |
| Lipi |
C |
T |
16: 75,362,418 (GRCm39) |
|
probably null |
Het |
| Lrrc17 |
C |
T |
5: 21,766,069 (GRCm39) |
R184W |
probably damaging |
Het |
| Mllt10 |
A |
G |
2: 18,128,567 (GRCm39) |
N183D |
probably damaging |
Het |
| Mterf2 |
C |
T |
10: 84,956,027 (GRCm39) |
G199D |
probably damaging |
Het |
| Mucl3 |
T |
C |
17: 35,949,084 (GRCm39) |
T172A |
unknown |
Het |
| Nat8f4 |
A |
T |
6: 85,877,976 (GRCm39) |
S182R |
probably benign |
Het |
| Ndrg3 |
C |
A |
2: 156,779,452 (GRCm39) |
E238* |
probably null |
Het |
| Nop14 |
A |
T |
5: 34,811,805 (GRCm39) |
L194H |
probably damaging |
Het |
| Obscn |
T |
C |
11: 58,972,731 (GRCm39) |
E2105G |
possibly damaging |
Het |
| Or5b104 |
A |
C |
19: 13,072,648 (GRCm39) |
Y121* |
probably null |
Het |
| Or5g9 |
A |
T |
2: 85,552,387 (GRCm39) |
T213S |
probably benign |
Het |
| Or7g17 |
A |
T |
9: 18,768,725 (GRCm39) |
Y259F |
possibly damaging |
Het |
| Or8k32 |
T |
A |
2: 86,368,725 (GRCm39) |
H176L |
possibly damaging |
Het |
| Pbx3 |
C |
T |
2: 34,068,240 (GRCm39) |
A320T |
probably benign |
Het |
| Pcdhac2 |
A |
T |
18: 37,279,197 (GRCm39) |
S726C |
probably damaging |
Het |
| Pcdhgb2 |
A |
G |
18: 37,823,816 (GRCm39) |
D269G |
probably damaging |
Het |
| Pcgf6 |
A |
T |
19: 47,034,271 (GRCm39) |
S257T |
probably damaging |
Het |
| Pclo |
A |
T |
5: 14,590,472 (GRCm39) |
H924L |
unknown |
Het |
| Per3 |
T |
A |
4: 151,127,135 (GRCm39) |
T129S |
possibly damaging |
Het |
| Pi4ka |
A |
T |
16: 17,120,924 (GRCm39) |
M1270K |
|
Het |
| Plec |
G |
A |
15: 76,063,750 (GRCm39) |
Q2277* |
probably null |
Het |
| Pnma1 |
T |
A |
12: 84,194,109 (GRCm39) |
K198M |
probably damaging |
Het |
| Prc1 |
T |
A |
7: 79,954,515 (GRCm39) |
F196L |
possibly damaging |
Het |
| Prkcz |
T |
C |
4: 155,441,962 (GRCm39) |
T57A |
probably damaging |
Het |
| Repin1 |
G |
T |
6: 48,574,279 (GRCm39) |
E403* |
probably null |
Het |
| Robo4 |
A |
G |
9: 37,313,931 (GRCm39) |
M61V |
possibly damaging |
Het |
| Rps12 |
C |
T |
10: 23,661,575 (GRCm39) |
V79I |
probably benign |
Het |
| Rsph3a |
A |
G |
17: 8,198,020 (GRCm39) |
K466E |
probably benign |
Het |
| Scly |
A |
T |
1: 91,236,089 (GRCm39) |
I168F |
probably damaging |
Het |
| Setd1a |
T |
A |
7: 127,384,225 (GRCm39) |
F359I |
unknown |
Het |
| Sh3tc1 |
A |
G |
5: 35,864,201 (GRCm39) |
L662P |
possibly damaging |
Het |
| Slc12a5 |
T |
C |
2: 164,834,372 (GRCm39) |
W798R |
probably damaging |
Het |
| Slc16a6 |
C |
T |
11: 109,364,281 (GRCm39) |
R13Q |
unknown |
Het |
| Slco1a8 |
T |
G |
6: 141,933,460 (GRCm39) |
M462L |
probably benign |
Het |
| Smarcad1 |
A |
G |
6: 65,029,766 (GRCm39) |
D118G |
possibly damaging |
Het |
| Sos2 |
T |
C |
12: 69,653,989 (GRCm39) |
T788A |
probably damaging |
Het |
| Syvn1 |
A |
G |
19: 6,098,396 (GRCm39) |
E75G |
probably null |
Het |
| Thpo |
T |
C |
16: 20,545,144 (GRCm39) |
E103G |
probably benign |
Het |
| Trav7d-3 |
A |
T |
14: 52,982,193 (GRCm39) |
E78V |
possibly damaging |
Het |
| Uap1 |
A |
G |
1: 169,986,332 (GRCm39) |
S217P |
probably damaging |
Het |
| Unc45a |
T |
G |
7: 79,981,310 (GRCm39) |
R497S |
probably damaging |
Het |
| Upf1 |
A |
G |
8: 70,791,534 (GRCm39) |
|
probably null |
Het |
| Usp47 |
A |
T |
7: 111,646,177 (GRCm39) |
K28M |
probably damaging |
Het |
| Wdr72 |
A |
C |
9: 74,126,054 (GRCm39) |
T1062P |
probably damaging |
Het |
| Wnt7b |
A |
T |
15: 85,421,646 (GRCm39) |
C339S |
probably damaging |
Het |
| Zfp954 |
G |
T |
7: 7,118,470 (GRCm39) |
T358K |
probably benign |
Het |
| Zmynd15 |
G |
T |
11: 70,350,278 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Ablim1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Ablim1
|
APN |
19 |
57,056,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00466:Ablim1
|
APN |
19 |
57,056,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00478:Ablim1
|
APN |
19 |
57,056,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00847:Ablim1
|
APN |
19 |
57,140,722 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL01063:Ablim1
|
APN |
19 |
57,049,760 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01304:Ablim1
|
APN |
19 |
57,204,153 (GRCm39) |
missense |
probably benign |
|
|
IGL01385:Ablim1
|
APN |
19 |
57,057,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01707:Ablim1
|
APN |
19 |
57,027,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02386:Ablim1
|
APN |
19 |
57,123,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02427:Ablim1
|
APN |
19 |
57,068,312 (GRCm39) |
splice site |
probably benign |
|
|
IGL02498:Ablim1
|
APN |
19 |
57,140,751 (GRCm39) |
nonsense |
probably null |
|
|
A9681:Ablim1
|
UTSW |
19 |
57,161,755 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0089:Ablim1
|
UTSW |
19 |
57,031,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0226:Ablim1
|
UTSW |
19 |
57,032,302 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1419:Ablim1
|
UTSW |
19 |
57,123,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Ablim1
|
UTSW |
19 |
57,056,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1587:Ablim1
|
UTSW |
19 |
57,071,979 (GRCm39) |
start codon destroyed |
probably null |
0.99 |
|
R1588:Ablim1
|
UTSW |
19 |
57,071,979 (GRCm39) |
start codon destroyed |
probably null |
0.99 |
|
R1935:Ablim1
|
UTSW |
19 |
57,204,397 (GRCm39) |
start gained |
probably null |
|
|
R1936:Ablim1
|
UTSW |
19 |
57,204,397 (GRCm39) |
start gained |
probably null |
|
|
R2021:Ablim1
|
UTSW |
19 |
57,035,450 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2110:Ablim1
|
UTSW |
19 |
57,032,245 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2270:Ablim1
|
UTSW |
19 |
57,065,863 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2509:Ablim1
|
UTSW |
19 |
57,140,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3621:Ablim1
|
UTSW |
19 |
57,140,735 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3732:Ablim1
|
UTSW |
19 |
57,037,892 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3732:Ablim1
|
UTSW |
19 |
57,037,892 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3733:Ablim1
|
UTSW |
19 |
57,037,892 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3734:Ablim1
|
UTSW |
19 |
57,037,892 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3878:Ablim1
|
UTSW |
19 |
57,025,642 (GRCm39) |
splice site |
probably null |
|
|
R4354:Ablim1
|
UTSW |
19 |
57,143,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4543:Ablim1
|
UTSW |
19 |
57,065,874 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4749:Ablim1
|
UTSW |
19 |
57,204,153 (GRCm39) |
missense |
probably benign |
|
|
R4860:Ablim1
|
UTSW |
19 |
57,068,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4860:Ablim1
|
UTSW |
19 |
57,068,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5072:Ablim1
|
UTSW |
19 |
57,062,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5277:Ablim1
|
UTSW |
19 |
57,143,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5331:Ablim1
|
UTSW |
19 |
57,143,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5354:Ablim1
|
UTSW |
19 |
57,119,355 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5893:Ablim1
|
UTSW |
19 |
57,204,285 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5958:Ablim1
|
UTSW |
19 |
57,030,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6435:Ablim1
|
UTSW |
19 |
57,049,787 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6460:Ablim1
|
UTSW |
19 |
57,068,271 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6642:Ablim1
|
UTSW |
19 |
57,119,284 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6662:Ablim1
|
UTSW |
19 |
57,062,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6705:Ablim1
|
UTSW |
19 |
57,204,253 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7111:Ablim1
|
UTSW |
19 |
57,062,309 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7291:Ablim1
|
UTSW |
19 |
57,204,340 (GRCm39) |
missense |
probably benign |
|
|
R7363:Ablim1
|
UTSW |
19 |
57,204,173 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7901:Ablim1
|
UTSW |
19 |
57,119,434 (GRCm39) |
splice site |
probably null |
|
|
R7974:Ablim1
|
UTSW |
19 |
57,033,405 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8087:Ablim1
|
UTSW |
19 |
57,170,688 (GRCm39) |
missense |
|
|
|
R8120:Ablim1
|
UTSW |
19 |
57,035,360 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8277:Ablim1
|
UTSW |
19 |
57,204,351 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8339:Ablim1
|
UTSW |
19 |
57,032,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8536:Ablim1
|
UTSW |
19 |
57,170,718 (GRCm39) |
intron |
probably benign |
|
|
R8857:Ablim1
|
UTSW |
19 |
57,119,287 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8875:Ablim1
|
UTSW |
19 |
57,119,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8983:Ablim1
|
UTSW |
19 |
57,227,644 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9055:Ablim1
|
UTSW |
19 |
57,030,398 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9475:Ablim1
|
UTSW |
19 |
57,227,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9505:Ablim1
|
UTSW |
19 |
57,185,782 (GRCm39) |
intron |
probably benign |
|
|
R9695:Ablim1
|
UTSW |
19 |
57,170,739 (GRCm39) |
missense |
|
|
|
R9762:Ablim1
|
UTSW |
19 |
57,025,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCCTTACTCGGTAGCTTAAAGG -3'
(R):5'- TCATACTGAAAGCCTGATCGGG -3'
Sequencing Primer
(F):5'- ACTCGGTAGCTTAAAGGTTGCTAAG -3'
(R):5'- ATCGGGCTGAACTTCAGGTC -3'
|
| Posted On |
2020-06-30 |
Incidental Mutation