Incidental Mutation 'R9404:Megf6'
| ID |
711391 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Megf6
|
| Ensembl Gene |
ENSMUSG00000057751 |
| Gene Name |
multiple EGF-like-domains 6 |
| Synonyms |
2600001P17Rik, Egfl3 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9404 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
154255187-154360170 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 154348225 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 902
(C902S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000030897
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030897]
[ENSMUST00000152159]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000030897
Gene: ENSMUSG00000057751
AA Change: C902S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
EGF_CA
|
122 |
162 |
1.54e-6 |
SMART |
|
EGF_CA
|
163 |
203 |
2.08e-12 |
SMART |
|
EGF
|
207 |
245 |
5.4e-2 |
SMART |
|
EGF
|
249 |
286 |
2.39e-3 |
SMART |
|
EGF_CA
|
287 |
327 |
4.96e-10 |
SMART |
|
EGF
|
336 |
373 |
1.64e-1 |
SMART |
|
EGF
|
377 |
413 |
1.99e1 |
SMART |
|
EGF_CA
|
414 |
454 |
7.4e-9 |
SMART |
|
EGF
|
521 |
554 |
4.26e0 |
SMART |
|
EGF_Lam
|
570 |
609 |
1.19e-3 |
SMART |
|
EGF_like
|
613 |
652 |
5.29e-1 |
SMART |
|
EGF
|
642 |
685 |
2.2e1 |
SMART |
|
EGF_Lam
|
656 |
697 |
1.04e-3 |
SMART |
|
EGF
|
687 |
730 |
1.59e1 |
SMART |
|
EGF_like
|
701 |
742 |
2.27e0 |
SMART |
|
EGF_Lam
|
746 |
784 |
1.33e-1 |
SMART |
|
EGF
|
783 |
816 |
2.85e-1 |
SMART |
|
EGF_Lam
|
832 |
871 |
3.88e-3 |
SMART |
|
EGF_Lam
|
875 |
915 |
3.25e-5 |
SMART |
|
EGF
|
914 |
946 |
4.7e-2 |
SMART |
|
EGF_like
|
962 |
1001 |
1.69e-1 |
SMART |
|
EGF
|
1000 |
1032 |
7.02e-1 |
SMART |
|
EGF_Lam
|
1048 |
1087 |
3.1e-2 |
SMART |
|
EGF
|
1077 |
1118 |
7.53e-1 |
SMART |
|
EGF_like
|
1091 |
1130 |
5.59e-1 |
SMART |
|
EGF
|
1129 |
1161 |
5.04e-2 |
SMART |
|
EGF_Lam
|
1177 |
1216 |
2.94e-3 |
SMART |
|
EGF
|
1206 |
1248 |
1.87e1 |
SMART |
|
EGF_Lam
|
1220 |
1260 |
3.1e-2 |
SMART |
|
EGF
|
1259 |
1291 |
1.73e0 |
SMART |
|
EGF
|
1302 |
1334 |
6.55e-1 |
SMART |
|
EGF
|
1345 |
1377 |
4.39e-2 |
SMART |
|
EGF_Lam
|
1393 |
1432 |
7.64e-2 |
SMART |
|
EGF_Lam
|
1436 |
1475 |
2.64e-5 |
SMART |
|
EGF_like
|
1465 |
1506 |
4.2e1 |
SMART |
|
EGF_Lam
|
1479 |
1518 |
1.19e-3 |
SMART |
|
EGF
|
1517 |
1549 |
1.84e1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128700
|
| SMART Domains |
Protein: ENSMUSP00000117277
Gene: ENSMUSG00000057751
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_Lam
|
3 |
42 |
3.1e-2 |
SMART |
|
EGF
|
32 |
73 |
7.53e-1 |
SMART |
|
EGF_like
|
46 |
85 |
8.92e-1 |
SMART |
|
EGF
|
84 |
116 |
7.13e-2 |
SMART |
|
EGF
|
127 |
159 |
1.73e0 |
SMART |
|
EGF
|
170 |
202 |
6.55e-1 |
SMART |
|
EGF
|
213 |
245 |
4.39e-2 |
SMART |
|
EGF_Lam
|
261 |
300 |
7.64e-2 |
SMART |
|
EGF
|
299 |
331 |
1.51e0 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000152159
AA Change: C794S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000121641
Gene: ENSMUSG00000057751
AA Change: C794S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
EGF_CA
|
55 |
95 |
2.08e-12 |
SMART |
|
EGF
|
99 |
137 |
5.4e-2 |
SMART |
|
EGF
|
141 |
178 |
2.39e-3 |
SMART |
|
EGF_CA
|
179 |
219 |
4.96e-10 |
SMART |
|
EGF
|
228 |
265 |
1.64e-1 |
SMART |
|
EGF
|
269 |
305 |
1.99e1 |
SMART |
|
EGF_CA
|
306 |
346 |
7.4e-9 |
SMART |
|
EGF
|
413 |
446 |
4.26e0 |
SMART |
|
EGF_Lam
|
462 |
501 |
1.19e-3 |
SMART |
|
EGF_like
|
505 |
544 |
5.29e-1 |
SMART |
|
EGF
|
534 |
577 |
2.2e1 |
SMART |
|
EGF_Lam
|
548 |
589 |
1.04e-3 |
SMART |
|
EGF
|
579 |
622 |
1.59e1 |
SMART |
|
EGF_like
|
593 |
634 |
2.27e0 |
SMART |
|
EGF_Lam
|
638 |
676 |
1.33e-1 |
SMART |
|
EGF
|
675 |
708 |
2.85e-1 |
SMART |
|
EGF_Lam
|
724 |
763 |
3.88e-3 |
SMART |
|
EGF_Lam
|
767 |
807 |
3.25e-5 |
SMART |
|
EGF
|
806 |
838 |
4.7e-2 |
SMART |
|
EGF_Lam
|
854 |
893 |
2.56e-3 |
SMART |
|
EGF
|
892 |
924 |
2.02e-1 |
SMART |
|
EGF
|
935 |
967 |
7.13e-2 |
SMART |
|
EGF
|
978 |
1010 |
1.73e0 |
SMART |
|
EGF
|
1021 |
1053 |
6.55e-1 |
SMART |
|
EGF
|
1064 |
1096 |
4.39e-2 |
SMART |
|
EGF
|
1107 |
1139 |
4.97e-1 |
SMART |
|
EGF
|
1159 |
1191 |
1.84e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 74 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acot11 |
T |
C |
4: 106,615,509 (GRCm39) |
K314R |
possibly damaging |
Het |
| Armt1 |
AC |
A |
10: 4,400,848 (GRCm39) |
|
probably null |
Het |
| Atad5 |
T |
C |
11: 80,005,064 (GRCm39) |
V1167A |
probably damaging |
Het |
| Bbs12 |
T |
C |
3: 37,373,557 (GRCm39) |
S2P |
probably damaging |
Het |
| Cdh11 |
A |
T |
8: 103,406,254 (GRCm39) |
L73Q |
probably damaging |
Het |
| Cdk15 |
A |
G |
1: 59,328,914 (GRCm39) |
E274G |
possibly damaging |
Het |
| Col27a1 |
T |
C |
4: 63,194,178 (GRCm39) |
V845A |
possibly damaging |
Het |
| Cyp3a11 |
T |
C |
5: 145,799,258 (GRCm39) |
T310A |
probably benign |
Het |
| Efcab5 |
G |
A |
11: 77,022,934 (GRCm39) |
T593I |
probably damaging |
Het |
| Ewsr1 |
A |
G |
11: 5,022,940 (GRCm39) |
M388T |
unknown |
Het |
| Fat2 |
A |
G |
11: 55,144,348 (GRCm39) |
|
probably null |
Het |
| Gm8225 |
T |
A |
17: 26,762,034 (GRCm39) |
I75N |
probably damaging |
Het |
| Gsap |
A |
G |
5: 21,474,919 (GRCm39) |
Y526C |
probably damaging |
Het |
| Hk1 |
T |
A |
10: 62,131,859 (GRCm39) |
I203F |
possibly damaging |
Het |
| Insl5 |
T |
C |
4: 102,875,535 (GRCm39) |
R72G |
probably benign |
Het |
| Iqcb1 |
T |
C |
16: 36,671,632 (GRCm39) |
V321A |
probably damaging |
Het |
| Iqcd |
A |
C |
5: 120,738,601 (GRCm39) |
T140P |
|
Het |
| Kcnt2 |
T |
A |
1: 140,353,107 (GRCm39) |
I272K |
probably damaging |
Het |
| Klhl25 |
A |
C |
7: 75,515,153 (GRCm39) |
I20L |
probably benign |
Het |
| Krt1 |
AAGCTGCCACCCCCAAAGCCACCACCGCCGTAGCTGCCACCCCCAAAGCCACCACCGCCGTAGCTGCCACCCCCAAAGCCACCAC |
AAGCTGCCACCCCCAAAGCCACCACCGCCGTAGCTGCCACCCCCAAAGCCACCAC |
15: 101,758,813 (GRCm39) |
|
probably benign |
Het |
| Lrba |
T |
C |
3: 86,205,224 (GRCm39) |
V356A |
probably damaging |
Het |
| Mast4 |
A |
G |
13: 102,887,933 (GRCm39) |
Y1159H |
probably damaging |
Het |
| Mavs |
T |
A |
2: 131,083,818 (GRCm39) |
L105Q |
probably damaging |
Het |
| Mmp17 |
A |
G |
5: 129,682,741 (GRCm39) |
D460G |
possibly damaging |
Het |
| Myh2 |
G |
T |
11: 67,070,454 (GRCm39) |
A466S |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,147,788 (GRCm39) |
N2744D |
probably damaging |
Het |
| Oga |
CTCGGGTC |
CTC |
19: 45,743,096 (GRCm39) |
|
probably null |
Het |
| Or13a26 |
T |
A |
7: 140,284,722 (GRCm39) |
L186H |
probably damaging |
Het |
| Or2a12 |
T |
C |
6: 42,904,750 (GRCm39) |
V195A |
probably benign |
Het |
| Or2aj4 |
C |
T |
16: 19,384,731 (GRCm39) |
V301M |
probably benign |
Het |
| Or4a27 |
T |
A |
2: 88,559,551 (GRCm39) |
M131L |
probably benign |
Het |
| Or6d13 |
T |
G |
6: 116,517,708 (GRCm39) |
I98S |
probably damaging |
Het |
| Or8g55 |
A |
T |
9: 39,784,708 (GRCm39) |
I46F |
possibly damaging |
Het |
| Parpbp |
A |
G |
10: 87,950,411 (GRCm39) |
V323A |
possibly damaging |
Het |
| Pax5 |
G |
A |
4: 44,645,565 (GRCm39) |
P255S |
possibly damaging |
Het |
| Pcdhga2 |
A |
G |
18: 37,803,067 (GRCm39) |
T304A |
probably benign |
Het |
| Pcsk1 |
T |
G |
13: 75,280,342 (GRCm39) |
S722R |
probably benign |
Het |
| Pcsk9 |
C |
A |
4: 106,311,723 (GRCm39) |
R218L |
probably damaging |
Het |
| Pds5a |
T |
A |
5: 65,776,307 (GRCm39) |
I96F |
probably damaging |
Het |
| Pkdrej |
C |
A |
15: 85,703,270 (GRCm39) |
V889L |
probably benign |
Het |
| Plekhh2 |
A |
T |
17: 84,878,468 (GRCm39) |
|
probably null |
Het |
| Pnn |
A |
G |
12: 59,118,758 (GRCm39) |
E447G |
probably damaging |
Het |
| Ppp2r3d |
A |
G |
9: 101,025,840 (GRCm39) |
L289P |
probably damaging |
Het |
| Ppp6r2 |
A |
G |
15: 89,152,753 (GRCm39) |
H298R |
probably benign |
Het |
| Ptpn23 |
T |
C |
9: 110,216,025 (GRCm39) |
N1277S |
|
Het |
| Pus10 |
T |
A |
11: 23,661,202 (GRCm39) |
F263L |
possibly damaging |
Het |
| Rexo5 |
A |
G |
7: 119,400,542 (GRCm39) |
Y109C |
probably damaging |
Het |
| Rnf185 |
A |
T |
11: 3,382,615 (GRCm39) |
C23* |
probably null |
Het |
| Runx1 |
T |
C |
16: 92,485,915 (GRCm39) |
N140D |
probably benign |
Het |
| Sbf2 |
T |
C |
7: 110,040,702 (GRCm39) |
Q375R |
possibly damaging |
Het |
| Scn9a |
G |
A |
2: 66,357,040 (GRCm39) |
T1087I |
probably benign |
Het |
| Sh2b1 |
TGGGGACCAGCTCAGCCACGGGGACCAGCTC |
TGGGGACCAGCTCAGCCACGGGGACCAGCTCAGCCACGGGGACCAGCTC |
7: 126,066,742 (GRCm39) |
|
probably benign |
Het |
| Sh2b1 |
TC |
TCAGCCACGGGGACCAGCCC |
7: 126,066,771 (GRCm39) |
|
probably benign |
Het |
| Slc7a11 |
T |
C |
3: 50,335,488 (GRCm39) |
H350R |
possibly damaging |
Het |
| Spaca6 |
T |
C |
17: 18,057,800 (GRCm39) |
C155R |
probably damaging |
Het |
| Spire2 |
C |
T |
8: 124,090,077 (GRCm39) |
R580* |
probably null |
Het |
| Srgap3 |
A |
T |
6: 112,706,616 (GRCm39) |
M851K |
probably benign |
Het |
| Themis |
A |
G |
10: 28,665,743 (GRCm39) |
D602G |
probably benign |
Het |
| Tlcd4 |
T |
C |
3: 121,028,731 (GRCm39) |
N52S |
probably benign |
Het |
| Trak2 |
T |
C |
1: 58,960,296 (GRCm39) |
T236A |
possibly damaging |
Het |
| Trrap |
T |
C |
5: 144,752,225 (GRCm39) |
C1709R |
possibly damaging |
Het |
| Ttn |
A |
T |
2: 76,584,500 (GRCm39) |
S22203T |
probably damaging |
Het |
| Tut7 |
A |
T |
13: 59,947,701 (GRCm39) |
N873K |
probably benign |
Het |
| Ube3a |
A |
G |
7: 58,936,763 (GRCm39) |
T701A |
probably damaging |
Het |
| Ufl1 |
T |
C |
4: 25,275,912 (GRCm39) |
I164V |
probably benign |
Het |
| Vcpip1 |
T |
C |
1: 9,817,856 (GRCm39) |
T176A |
probably damaging |
Het |
| Virma |
T |
A |
4: 11,513,626 (GRCm39) |
D493E |
probably benign |
Het |
| Vmn2r77 |
T |
A |
7: 86,451,247 (GRCm39) |
W378R |
probably benign |
Het |
| Vps13b |
A |
T |
15: 35,876,565 (GRCm39) |
T2799S |
probably damaging |
Het |
| Vps8 |
T |
C |
16: 21,426,927 (GRCm39) |
S1337P |
probably benign |
Het |
| Zfp235 |
A |
T |
7: 23,839,862 (GRCm39) |
I94F |
possibly damaging |
Het |
| Zfp3 |
A |
G |
11: 70,663,366 (GRCm39) |
K442E |
probably damaging |
Het |
| Zfp418 |
A |
T |
7: 7,185,104 (GRCm39) |
I356F |
possibly damaging |
Het |
| Zfp790 |
G |
A |
7: 29,525,185 (GRCm39) |
G68S |
probably benign |
Het |
|
| Other mutations in Megf6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01122:Megf6
|
APN |
4 |
154,338,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Megf6
|
APN |
4 |
154,337,020 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01512:Megf6
|
APN |
4 |
154,347,040 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01824:Megf6
|
APN |
4 |
154,336,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02172:Megf6
|
APN |
4 |
154,355,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02727:Megf6
|
APN |
4 |
154,337,606 (GRCm39) |
splice site |
probably null |
|
|
IGL02966:Megf6
|
APN |
4 |
154,338,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Didactic
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0118:Megf6
|
UTSW |
4 |
154,339,098 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0220:Megf6
|
UTSW |
4 |
154,342,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Megf6
|
UTSW |
4 |
154,339,092 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0383:Megf6
|
UTSW |
4 |
154,349,783 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0417:Megf6
|
UTSW |
4 |
154,352,424 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0526:Megf6
|
UTSW |
4 |
154,343,398 (GRCm39) |
missense |
probably benign |
|
|
R0528:Megf6
|
UTSW |
4 |
154,343,630 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0928:Megf6
|
UTSW |
4 |
154,261,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1311:Megf6
|
UTSW |
4 |
154,348,239 (GRCm39) |
splice site |
probably null |
|
|
R1458:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1470:Megf6
|
UTSW |
4 |
154,336,876 (GRCm39) |
splice site |
probably benign |
|
|
R1476:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1479:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1624:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1626:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1638:Megf6
|
UTSW |
4 |
154,346,967 (GRCm39) |
splice site |
probably benign |
|
|
R1777:Megf6
|
UTSW |
4 |
154,355,147 (GRCm39) |
nonsense |
probably null |
|
|
R1831:Megf6
|
UTSW |
4 |
154,355,134 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1944:Megf6
|
UTSW |
4 |
154,340,523 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1984:Megf6
|
UTSW |
4 |
154,352,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2448:Megf6
|
UTSW |
4 |
154,351,102 (GRCm39) |
splice site |
probably null |
|
|
R2880:Megf6
|
UTSW |
4 |
154,337,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4032:Megf6
|
UTSW |
4 |
154,261,550 (GRCm39) |
nonsense |
probably null |
|
|
R4058:Megf6
|
UTSW |
4 |
154,326,989 (GRCm39) |
splice site |
probably benign |
|
|
R4672:Megf6
|
UTSW |
4 |
154,333,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4688:Megf6
|
UTSW |
4 |
154,338,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4752:Megf6
|
UTSW |
4 |
154,336,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:Megf6
|
UTSW |
4 |
154,338,738 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4909:Megf6
|
UTSW |
4 |
154,349,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Megf6
|
UTSW |
4 |
154,338,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4981:Megf6
|
UTSW |
4 |
154,351,907 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4990:Megf6
|
UTSW |
4 |
154,351,683 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5001:Megf6
|
UTSW |
4 |
154,352,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5189:Megf6
|
UTSW |
4 |
154,336,980 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5210:Megf6
|
UTSW |
4 |
154,354,273 (GRCm39) |
intron |
probably benign |
|
|
R5220:Megf6
|
UTSW |
4 |
154,338,295 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5250:Megf6
|
UTSW |
4 |
154,340,467 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5697:Megf6
|
UTSW |
4 |
154,342,686 (GRCm39) |
missense |
probably null |
0.15 |
|
R5808:Megf6
|
UTSW |
4 |
154,352,119 (GRCm39) |
missense |
probably benign |
|
|
R5916:Megf6
|
UTSW |
4 |
154,333,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6054:Megf6
|
UTSW |
4 |
154,347,636 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6075:Megf6
|
UTSW |
4 |
154,347,056 (GRCm39) |
nonsense |
probably null |
|
|
R6515:Megf6
|
UTSW |
4 |
154,343,376 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6599:Megf6
|
UTSW |
4 |
154,342,544 (GRCm39) |
splice site |
probably null |
|
|
R6811:Megf6
|
UTSW |
4 |
154,336,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Megf6
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7023:Megf6
|
UTSW |
4 |
154,338,602 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7117:Megf6
|
UTSW |
4 |
154,343,379 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7163:Megf6
|
UTSW |
4 |
154,351,898 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7345:Megf6
|
UTSW |
4 |
154,351,772 (GRCm39) |
missense |
probably benign |
|
|
R7580:Megf6
|
UTSW |
4 |
154,355,201 (GRCm39) |
nonsense |
probably null |
|
|
R7649:Megf6
|
UTSW |
4 |
154,349,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7702:Megf6
|
UTSW |
4 |
154,354,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8010:Megf6
|
UTSW |
4 |
154,354,964 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8175:Megf6
|
UTSW |
4 |
154,353,076 (GRCm39) |
nonsense |
probably null |
|
|
R8231:Megf6
|
UTSW |
4 |
154,336,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8436:Megf6
|
UTSW |
4 |
154,349,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8460:Megf6
|
UTSW |
4 |
154,350,634 (GRCm39) |
nonsense |
probably null |
|
|
R8738:Megf6
|
UTSW |
4 |
154,352,436 (GRCm39) |
missense |
probably benign |
|
|
R8854:Megf6
|
UTSW |
4 |
154,352,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Megf6
|
UTSW |
4 |
154,326,860 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9098:Megf6
|
UTSW |
4 |
154,354,160 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9147:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9148:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9161:Megf6
|
UTSW |
4 |
154,352,172 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9355:Megf6
|
UTSW |
4 |
154,338,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9386:Megf6
|
UTSW |
4 |
154,340,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9469:Megf6
|
UTSW |
4 |
154,335,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9472:Megf6
|
UTSW |
4 |
154,333,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9777:Megf6
|
UTSW |
4 |
154,343,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Megf6
|
UTSW |
4 |
154,322,283 (GRCm39) |
missense |
probably benign |
0.12 |
|
Z1177:Megf6
|
UTSW |
4 |
154,354,198 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,204 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,139 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Megf6
|
UTSW |
4 |
154,352,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
Z1177:Megf6
|
UTSW |
4 |
154,335,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGCTGCCAGAGAGGTATG -3'
(R):5'- CGATGGGAGACAGTACATGC -3'
Sequencing Primer
(F):5'- CACGATGCCCTGTGTTCTGATG -3'
(R):5'- CATGGTATGTGTGCACCAGAACAC -3'
|
| Posted On |
2022-05-16 |
Incidental Mutation