Incidental Mutation 'R0482:Nckap5'
| ID |
41997 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
038682-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0482 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 125954102 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 753
(S753P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000062229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057846
AA Change: S753P
PolyPhen 2
Score 0.921 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: S753P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112583
AA Change: S885P
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: S885P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159934
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161954
AA Change: S817P
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: S817P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Meta Mutation Damage Score |
0.0778 |
| Coding Region Coverage |
- 1x: 99.6%
- 3x: 98.8%
- 10x: 96.8%
- 20x: 93.4%
|
| Validation Efficiency |
95% (94/99) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
T |
C |
17: 9,207,255 (GRCm39) |
|
probably null |
Het |
| Abca13 |
G |
A |
11: 9,278,207 (GRCm39) |
G3129D |
possibly damaging |
Het |
| Acnat2 |
T |
C |
4: 49,383,534 (GRCm39) |
I6M |
probably benign |
Het |
| Adcy4 |
T |
A |
14: 56,012,029 (GRCm39) |
|
probably null |
Het |
| Agrn |
A |
G |
4: 156,258,012 (GRCm39) |
S1117P |
probably damaging |
Het |
| Anks1b |
A |
G |
10: 90,195,057 (GRCm39) |
N545S |
probably benign |
Het |
| Antxr1 |
C |
T |
6: 87,246,220 (GRCm39) |
|
probably null |
Het |
| Arhgef17 |
T |
C |
7: 100,529,828 (GRCm39) |
K476E |
probably damaging |
Het |
| Bptf |
T |
C |
11: 106,972,088 (GRCm39) |
S927G |
probably benign |
Het |
| Cacna1s |
C |
T |
1: 136,041,132 (GRCm39) |
T1286I |
probably benign |
Het |
| Ccdc174 |
T |
A |
6: 91,872,247 (GRCm39) |
M292K |
probably benign |
Het |
| Cdk5rap2 |
G |
A |
4: 70,328,506 (GRCm39) |
|
probably benign |
Het |
| Celsr3 |
T |
A |
9: 108,706,272 (GRCm39) |
Y918* |
probably null |
Het |
| Cep250 |
T |
C |
2: 155,806,894 (GRCm39) |
|
probably benign |
Het |
| Ces2h |
A |
G |
8: 105,746,903 (GRCm39) |
D513G |
possibly damaging |
Het |
| Clec2l |
A |
G |
6: 38,640,327 (GRCm39) |
T53A |
probably benign |
Het |
| Cntnap2 |
C |
T |
6: 45,692,750 (GRCm39) |
S77L |
probably benign |
Het |
| Cped1 |
A |
T |
6: 22,016,957 (GRCm39) |
H102L |
probably benign |
Het |
| Crim1 |
T |
A |
17: 78,680,008 (GRCm39) |
D916E |
probably benign |
Het |
| Csmd1 |
T |
A |
8: 16,283,115 (GRCm39) |
I614F |
probably damaging |
Het |
| Csnk1g1 |
G |
A |
9: 65,917,751 (GRCm39) |
E37K |
probably damaging |
Het |
| Ctnnbl1 |
T |
A |
2: 157,713,110 (GRCm39) |
|
probably null |
Het |
| Cuzd1 |
A |
T |
7: 130,911,601 (GRCm39) |
|
probably benign |
Het |
| Cyp4f16 |
T |
A |
17: 32,769,525 (GRCm39) |
V433D |
probably damaging |
Het |
| Ddi1 |
A |
G |
9: 6,266,144 (GRCm39) |
L75P |
probably damaging |
Het |
| Ddias |
G |
A |
7: 92,508,736 (GRCm39) |
A393V |
probably benign |
Het |
| Dgka |
A |
T |
10: 128,569,990 (GRCm39) |
Y123* |
probably null |
Het |
| Dlgap1 |
T |
C |
17: 70,823,185 (GRCm39) |
C57R |
probably benign |
Het |
| Dysf |
T |
A |
6: 84,129,387 (GRCm39) |
V1458D |
probably benign |
Het |
| Eif2ak4 |
T |
A |
2: 118,292,828 (GRCm39) |
Y1230N |
probably damaging |
Het |
| Fbxl7 |
A |
T |
15: 26,543,632 (GRCm39) |
S338R |
probably benign |
Het |
| Fgf23 |
A |
T |
6: 127,050,122 (GRCm39) |
T44S |
probably damaging |
Het |
| Fhip1b |
G |
A |
7: 105,033,419 (GRCm39) |
P599L |
possibly damaging |
Het |
| Folh1 |
A |
T |
7: 86,395,309 (GRCm39) |
|
probably benign |
Het |
| Gpsm2 |
A |
T |
3: 108,609,710 (GRCm39) |
|
probably benign |
Het |
| H2bc13 |
A |
G |
13: 21,900,295 (GRCm39) |
|
probably benign |
Het |
| Hdac2 |
T |
A |
10: 36,865,130 (GRCm39) |
|
probably benign |
Het |
| Il31ra |
G |
T |
13: 112,664,015 (GRCm39) |
T446N |
possibly damaging |
Het |
| Irf5 |
T |
A |
6: 29,535,369 (GRCm39) |
L199H |
probably benign |
Het |
| Kif18a |
T |
A |
2: 109,118,188 (GRCm39) |
M1K |
probably null |
Het |
| Kif4-ps |
A |
C |
12: 101,114,921 (GRCm39) |
I1017L |
probably benign |
Het |
| Klhl2 |
C |
T |
8: 65,211,164 (GRCm39) |
V295M |
probably benign |
Het |
| Krt75 |
A |
T |
15: 101,478,746 (GRCm39) |
M296K |
probably benign |
Het |
| Krt81 |
C |
A |
15: 101,361,508 (GRCm39) |
R24L |
possibly damaging |
Het |
| Lgr4 |
T |
C |
2: 109,838,437 (GRCm39) |
S439P |
probably damaging |
Het |
| Lhfpl2 |
C |
A |
13: 94,311,118 (GRCm39) |
N129K |
probably damaging |
Het |
| Lnx2 |
A |
G |
5: 146,955,771 (GRCm39) |
V675A |
probably damaging |
Het |
| Med13 |
T |
C |
11: 86,175,977 (GRCm39) |
T1673A |
probably benign |
Het |
| Mif |
A |
G |
10: 75,695,974 (GRCm39) |
V10A |
possibly damaging |
Het |
| Mki67 |
A |
T |
7: 135,301,158 (GRCm39) |
I1292N |
possibly damaging |
Het |
| Mylip |
C |
A |
13: 45,558,059 (GRCm39) |
N89K |
probably benign |
Het |
| Myo19 |
G |
T |
11: 84,800,245 (GRCm39) |
D877Y |
probably benign |
Het |
| Nlrc3 |
T |
C |
16: 3,783,056 (GRCm39) |
T118A |
possibly damaging |
Het |
| Nptx2 |
T |
C |
5: 144,490,269 (GRCm39) |
Y233H |
probably damaging |
Het |
| Nsl1 |
T |
A |
1: 190,795,237 (GRCm39) |
M1K |
probably null |
Het |
| Ntsr1 |
T |
A |
2: 180,142,849 (GRCm39) |
S213R |
possibly damaging |
Het |
| Or4c120 |
A |
T |
2: 89,000,975 (GRCm39) |
F194I |
probably benign |
Het |
| Or4c58 |
A |
G |
2: 89,674,513 (GRCm39) |
V268A |
probably benign |
Het |
| Or52n5 |
T |
A |
7: 104,588,021 (GRCm39) |
F96Y |
possibly damaging |
Het |
| Pde4d |
G |
A |
13: 110,073,244 (GRCm39) |
V347I |
probably benign |
Het |
| Pik3r4 |
T |
A |
9: 105,546,244 (GRCm39) |
S865T |
probably benign |
Het |
| Ppp2r2d |
A |
G |
7: 138,472,160 (GRCm39) |
R136G |
probably benign |
Het |
| Proser2 |
A |
C |
2: 6,118,721 (GRCm39) |
S41A |
probably damaging |
Het |
| Proz |
A |
T |
8: 13,123,460 (GRCm39) |
K244* |
probably null |
Het |
| Prpf38b |
A |
T |
3: 108,812,586 (GRCm39) |
L209H |
probably damaging |
Het |
| R3hdm1 |
C |
A |
1: 128,112,254 (GRCm39) |
A390E |
probably benign |
Het |
| Rb1cc1 |
A |
C |
1: 6,310,547 (GRCm39) |
D315A |
probably damaging |
Het |
| Rnf141 |
G |
A |
7: 110,436,345 (GRCm39) |
R28* |
probably null |
Het |
| Rps6kc1 |
A |
T |
1: 190,531,627 (GRCm39) |
S792T |
probably benign |
Het |
| Rxrg |
A |
G |
1: 167,458,606 (GRCm39) |
D233G |
possibly damaging |
Het |
| Sh2d7 |
A |
G |
9: 54,448,321 (GRCm39) |
N114S |
probably benign |
Het |
| Slc25a38 |
T |
C |
9: 119,949,899 (GRCm39) |
V205A |
probably benign |
Het |
| Slc4a10 |
T |
C |
2: 62,127,361 (GRCm39) |
|
probably benign |
Het |
| Spred1 |
T |
A |
2: 116,983,459 (GRCm39) |
|
probably null |
Het |
| Stt3b |
A |
G |
9: 115,077,635 (GRCm39) |
S706P |
probably benign |
Het |
| Tcerg1 |
C |
A |
18: 42,697,305 (GRCm39) |
|
probably benign |
Het |
| Tent5a |
T |
C |
9: 85,207,108 (GRCm39) |
Y230C |
probably damaging |
Het |
| Thsd4 |
A |
T |
9: 59,910,261 (GRCm39) |
I109N |
probably damaging |
Het |
| Ticrr |
C |
A |
7: 79,344,236 (GRCm39) |
P1367Q |
probably damaging |
Het |
| Trpv1 |
A |
G |
11: 73,130,255 (GRCm39) |
D146G |
probably damaging |
Het |
| Tubd1 |
T |
G |
11: 86,448,602 (GRCm39) |
V305G |
possibly damaging |
Het |
| Tubgcp4 |
T |
C |
2: 121,005,855 (GRCm39) |
L81P |
probably benign |
Het |
| Ubxn2b |
T |
A |
4: 6,196,404 (GRCm39) |
|
probably null |
Het |
| Usp36 |
A |
T |
11: 118,156,020 (GRCm39) |
S586T |
probably benign |
Het |
| Vcan |
T |
A |
13: 89,826,264 (GRCm39) |
D2220V |
probably damaging |
Het |
| Vmn1r173 |
T |
A |
7: 23,402,216 (GRCm39) |
N150K |
probably damaging |
Het |
| Vmn1r70 |
G |
A |
7: 10,368,204 (GRCm39) |
A231T |
probably damaging |
Het |
| Vmn2r97 |
A |
G |
17: 19,167,930 (GRCm39) |
D728G |
probably damaging |
Het |
| Zbtb40 |
T |
C |
4: 136,710,539 (GRCm39) |
E1200G |
probably damaging |
Het |
| Zfp365 |
A |
T |
10: 67,733,436 (GRCm39) |
V252D |
probably damaging |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
125,952,659 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
125,954,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
125,954,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
125,955,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
125,953,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
125,953,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCAACCCTGGACTTACAGCGTCTC -3'
(R):5'- CAGTGCCCTAGTGACTCCTGAAAAG -3'
Sequencing Primer
(F):5'- ACTTACAGCGTCTCCAGGG -3'
(R):5'- TCTCTGTGATGTACAGCCAGAATC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation