Mutagenetix > Incidental Mutation

Incidental Mutation 'R4802:Nav2'

472781

Institutional Source

Beutler Lab

Gene Symbol

Nav2

Ensembl Gene

ENSMUSG00000052512

Gene Name

neuron navigator 2

Synonyms

Rainb1, Unc53H2, 5330421F07Rik, POMFIL2, HELAD1, RAINB2

MMRRC Submission

042424-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.550) question?

Stock #

R4802 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

48608796-49259838 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 49195600 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Valine at position 992 (D992V)

Ref Sequence

ENSEMBL: ENSMUSP00000139045 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000064395] [ENSMUST00000183659] [ENSMUST00000184109] [ENSMUST00000184945]

AlphaFold

E9Q842

Predicted Effect

possibly damaging
Transcript: ENSMUST00000064395
AA Change: D992V

PolyPhen 2 Score 0.945 (Sensitivity: 0.80; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000067448
Gene: ENSMUSG00000052512
AA Change: D992V

Domain	Start	End	E-Value	Type
CH	84	187	1.58e-13	SMART
low complexity region	202	210	N/A	INTRINSIC
low complexity region	297	310	N/A	INTRINSIC
low complexity region	337	348	N/A	INTRINSIC
low complexity region	412	424	N/A	INTRINSIC
coiled coil region	486	516	N/A	INTRINSIC
low complexity region	580	591	N/A	INTRINSIC
low complexity region	613	625	N/A	INTRINSIC
low complexity region	640	662	N/A	INTRINSIC
low complexity region	846	857	N/A	INTRINSIC
low complexity region	920	944	N/A	INTRINSIC
low complexity region	947	967	N/A	INTRINSIC
low complexity region	990	1004	N/A	INTRINSIC
low complexity region	1062	1074	N/A	INTRINSIC
low complexity region	1343	1360	N/A	INTRINSIC
low complexity region	1368	1385	N/A	INTRINSIC
low complexity region	1417	1432	N/A	INTRINSIC
low complexity region	1454	1466	N/A	INTRINSIC
low complexity region	1526	1540	N/A	INTRINSIC
low complexity region	1614	1628	N/A	INTRINSIC
coiled coil region	1630	1717	N/A	INTRINSIC
low complexity region	1789	1800	N/A	INTRINSIC
coiled coil region	1841	1909	N/A	INTRINSIC
AAA	2093	2247	1.69e-5	SMART
low complexity region	2404	2430	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000183659
AA Change: D931V

PolyPhen 2 Score 0.862 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000139309
Gene: ENSMUSG00000052512
AA Change: D931V

Domain	Start	End	E-Value	Type
low complexity region	2	11	N/A	INTRINSIC
CH	23	126	6.19e-16	SMART
low complexity region	141	149	N/A	INTRINSIC
low complexity region	236	249	N/A	INTRINSIC
low complexity region	276	287	N/A	INTRINSIC
low complexity region	351	363	N/A	INTRINSIC
coiled coil region	425	455	N/A	INTRINSIC
low complexity region	519	530	N/A	INTRINSIC
low complexity region	552	564	N/A	INTRINSIC
low complexity region	579	601	N/A	INTRINSIC
low complexity region	785	796	N/A	INTRINSIC
low complexity region	859	883	N/A	INTRINSIC
low complexity region	886	906	N/A	INTRINSIC
low complexity region	929	943	N/A	INTRINSIC
low complexity region	1001	1013	N/A	INTRINSIC
low complexity region	1282	1299	N/A	INTRINSIC
low complexity region	1307	1324	N/A	INTRINSIC
low complexity region	1356	1371	N/A	INTRINSIC
low complexity region	1393	1405	N/A	INTRINSIC
low complexity region	1465	1479	N/A	INTRINSIC
low complexity region	1553	1567	N/A	INTRINSIC
coiled coil region	1569	1656	N/A	INTRINSIC
low complexity region	1728	1739	N/A	INTRINSIC
coiled coil region	1780	1848	N/A	INTRINSIC
AAA	2032	2186	1.69e-5	SMART
low complexity region	2343	2369	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000184109

SMART Domains

Protein: ENSMUSP00000138846
Gene: ENSMUSG00000052512

Domain	Start	End	E-Value	Type
low complexity region	154	171	N/A	INTRINSIC
low complexity region	179	196	N/A	INTRINSIC
low complexity region	228	243	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000184945
AA Change: D992V

PolyPhen 2 Score 0.945 (Sensitivity: 0.80; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000139045
Gene: ENSMUSG00000052512
AA Change: D992V

Domain	Start	End	E-Value	Type
CH	84	187	1.58e-13	SMART
low complexity region	202	210	N/A	INTRINSIC
low complexity region	297	310	N/A	INTRINSIC
low complexity region	337	348	N/A	INTRINSIC
low complexity region	412	424	N/A	INTRINSIC
coiled coil region	486	516	N/A	INTRINSIC
low complexity region	580	591	N/A	INTRINSIC
low complexity region	613	625	N/A	INTRINSIC
low complexity region	640	662	N/A	INTRINSIC
low complexity region	846	857	N/A	INTRINSIC
low complexity region	920	944	N/A	INTRINSIC
low complexity region	947	967	N/A	INTRINSIC
low complexity region	990	1004	N/A	INTRINSIC
low complexity region	1062	1074	N/A	INTRINSIC
low complexity region	1343	1360	N/A	INTRINSIC
low complexity region	1368	1385	N/A	INTRINSIC
low complexity region	1417	1432	N/A	INTRINSIC
low complexity region	1454	1466	N/A	INTRINSIC
low complexity region	1526	1540	N/A	INTRINSIC
low complexity region	1614	1628	N/A	INTRINSIC
coiled coil region	1630	1717	N/A	INTRINSIC
low complexity region	1789	1800	N/A	INTRINSIC
coiled coil region	1841	1909	N/A	INTRINSIC
AAA	2093	2247	1.69e-5	SMART
low complexity region	2404	2430	N/A	INTRINSIC

Meta Mutation Damage Score

0.1203

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.9%
20x: 94.3%

Validation Efficiency

97% (93/96)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Homozygous null mice display impaired olfaction and hearing, increased latency in a hot plate test, degeneration of the optic nerve, decreased exploration in new environments, and weight loss. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 167 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2310057J18Rik	A	G	10: 28,859,922 (GRCm39)		probably null	Het
4932416K20Rik	T	A	8: 105,523,664 (GRCm39)		noncoding transcript	Het
Aadacl3	A	G	4: 144,182,802 (GRCm39)	I222T	probably damaging	Het
Abca13	G	T	11: 9,472,341 (GRCm39)	G4249V	possibly damaging	Het
Abcb10	A	G	8: 124,693,266 (GRCm39)	V346A	probably benign	Het
Abcc2	A	T	19: 43,807,800 (GRCm39)	I814F	probably damaging	Het
Alkbh2	C	T	5: 114,262,287 (GRCm39)	E148K	probably damaging	Het
Ankrd28	A	C	14: 31,458,787 (GRCm39)	D335E	probably damaging	Het
Ankrd44	T	C	1: 54,801,475 (GRCm39)	H284R	probably damaging	Het
Arfgef3	G	T	10: 18,467,654 (GRCm39)	Q1849K	probably benign	Het
Bach1	T	A	16: 87,519,340 (GRCm39)	D543E	probably damaging	Het
Bahcc1	G	A	11: 120,173,051 (GRCm39)	V1558I	probably benign	Het
Bbs5	T	A	2: 69,485,958 (GRCm39)	W168R	probably damaging	Het
Bcar3	A	T	3: 122,323,243 (GRCm39)	D766V	probably benign	Het
C1ra	A	G	6: 124,490,727 (GRCm39)	D40G	probably benign	Het
Cbr4	T	C	8: 61,943,113 (GRCm39)		probably benign	Het
Ccdc138	G	A	10: 58,409,465 (GRCm39)	C598Y	probably damaging	Het
Cd200r3	T	A	16: 44,778,188 (GRCm39)	N197K	possibly damaging	Het
Cenpf	T	A	1: 189,383,417 (GRCm39)	E2634D	probably damaging	Het
Cisd2	T	C	3: 135,116,902 (GRCm39)	K63R	probably damaging	Het
Clca3a2	A	T	3: 144,513,112 (GRCm39)	S478T	possibly damaging	Het
Clptm1l	T	C	13: 73,755,981 (GRCm39)	M199T	possibly damaging	Het
Cntnap4	T	A	8: 113,500,222 (GRCm39)	S505T	possibly damaging	Het
Cr2	C	T	1: 194,845,619 (GRCm39)	G112D	probably damaging	Het
Crb2	T	A	2: 37,683,768 (GRCm39)	I1090N	probably benign	Het
Csmd3	G	T	15: 47,484,688 (GRCm39)	P3057Q	probably damaging	Het
Ctso	G	A	3: 81,861,547 (GRCm39)	V307I	probably damaging	Het
Cyp3a41b	T	A	5: 145,510,461 (GRCm39)	T138S	probably benign	Het
Dctn3	G	T	4: 41,719,904 (GRCm39)	Y67*	probably null	Het
Dennd4c	C	A	4: 86,738,121 (GRCm39)	Y918*	probably null	Het
Dlg5	C	T	14: 24,204,757 (GRCm39)	G1262D	probably damaging	Het
Dnaaf1	G	A	8: 120,304,100 (GRCm39)	G46D	probably benign	Het
Dnah6	A	G	6: 73,066,681 (GRCm39)	V2563A	probably damaging	Het
Dnajc13	A	G	9: 104,052,926 (GRCm39)	Y1679H	probably benign	Het
Eif2ak3	T	C	6: 70,864,877 (GRCm39)	Y578H	probably benign	Het
Endod1	C	T	9: 14,268,319 (GRCm39)	V389M	probably benign	Het
Entpd2	T	G	2: 25,289,776 (GRCm39)		probably null	Het
Ephb4	T	C	5: 137,363,768 (GRCm39)	L582P	probably damaging	Het
Eps15	T	C	4: 109,181,414 (GRCm39)	L316S	possibly damaging	Het
Erbb4	G	T	1: 68,369,405 (GRCm39)	T412K	probably damaging	Het
Fam117a	T	A	11: 95,254,896 (GRCm39)	F90I	probably damaging	Het
Fam187b	T	G	7: 30,676,515 (GRCm39)	V8G	possibly damaging	Het
Far1	T	A	7: 113,138,660 (GRCm39)	I59N	possibly damaging	Het
Fbxo34	T	A	14: 47,768,326 (GRCm39)	L562Q	probably damaging	Het
Frem1	T	A	4: 82,834,865 (GRCm39)		probably benign	Het
Gfra3	G	T	18: 34,853,245 (GRCm39)	P10Q	probably damaging	Het
Gm10619	T	A	7: 73,459,773 (GRCm39)		noncoding transcript	Het
Gm19965	T	A	1: 116,749,626 (GRCm39)	Y436N	probably benign	Het
Gm28042	T	C	2: 119,872,535 (GRCm39)		probably benign	Het
Gm4953	A	T	1: 158,995,988 (GRCm39)		noncoding transcript	Het
Gm5799	A	T	14: 43,782,005 (GRCm39)	H59L	probably damaging	Het
Gmppb	T	A	9: 107,927,416 (GRCm39)	V121E	probably benign	Het
Ighv7-4	G	C	12: 114,186,899 (GRCm39)		probably benign	Het
Ipo4	A	G	14: 55,868,671 (GRCm39)	S446P	probably damaging	Het
Itpr2	T	C	6: 146,272,829 (GRCm39)	T855A	probably damaging	Het
Jaml	T	C	9: 45,012,362 (GRCm39)	I283T	possibly damaging	Het
Klhl32	T	C	4: 24,649,698 (GRCm39)	Y399C	possibly damaging	Het
Lratd2	C	A	15: 60,695,793 (GRCm39)		probably benign	Het
Lrriq1	G	A	10: 103,057,179 (GRCm39)	T207I	probably benign	Het
Lrriq3	A	T	3: 154,893,607 (GRCm39)	H436L	probably benign	Het
Mad2l1bp	T	C	17: 46,459,189 (GRCm39)	K114E	possibly damaging	Het
Mamstr	T	C	7: 45,291,842 (GRCm39)	V64A	possibly damaging	Het
Map4	T	A	9: 109,864,325 (GRCm39)	S517T	probably benign	Het
Matn1	A	T	4: 130,677,336 (GRCm39)	I182F	possibly damaging	Het
Mcm3	A	G	1: 20,880,380 (GRCm39)	I484T	probably damaging	Het
Med13	T	A	11: 86,169,599 (GRCm39)	I1922F	probably damaging	Het
Metap2	A	G	10: 93,704,757 (GRCm39)	V137A	probably damaging	Het
Mex3d	A	G	10: 80,222,788 (GRCm39)	V156A	possibly damaging	Het
Mfsd6	G	A	1: 52,748,755 (GRCm39)	P37S	probably benign	Het
Mmut	A	G	17: 41,248,242 (GRCm39)	T90A	probably benign	Het
Mrgprx1	A	C	7: 47,670,959 (GRCm39)	S263A	possibly damaging	Het
Mrtfa	T	C	15: 80,989,000 (GRCm39)	E7G	probably benign	Het
Msantd5f6	C	T	4: 73,319,504 (GRCm39)	W80*	probably null	Het
Msl1	C	T	11: 98,694,795 (GRCm39)	R505*	probably null	Het
Mta2	T	C	19: 8,923,215 (GRCm39)	S96P	probably damaging	Het
Mtr	A	T	13: 12,210,137 (GRCm39)	N986K	probably benign	Het
Mutyh	C	T	4: 116,674,226 (GRCm39)	T259I	probably benign	Het
Myof	T	C	19: 37,934,186 (GRCm39)	T908A	probably benign	Het
Neb	T	C	2: 52,090,715 (GRCm39)	T1352A	possibly damaging	Het
Nfix	CAAAAA	CAAAA	8: 85,442,876 (GRCm39)		probably null	Het
Nudt19	T	C	7: 35,255,564 (GRCm39)		probably benign	Het
Nudt6	G	A	3: 37,459,503 (GRCm39)	R161C	probably benign	Het
Olr1	A	G	6: 129,465,053 (GRCm39)	F141S	possibly damaging	Het
Oprl1	G	T	2: 181,361,046 (GRCm39)	M340I	probably benign	Het
Or10ag57	T	A	2: 87,218,553 (GRCm39)	V168E	probably benign	Het
Or10d1	T	G	9: 39,484,154 (GRCm39)	M134L	probably benign	Het
Or11g2	A	G	14: 50,856,479 (GRCm39)	T267A	probably benign	Het
Or14j1	T	C	17: 38,146,240 (GRCm39)	Y117H	probably damaging	Het
Or1e17	T	A	11: 73,831,696 (GRCm39)	I208K	possibly damaging	Het
Or2ak6	T	C	11: 58,592,617 (GRCm39)	V30A	probably benign	Het
Or2r2	A	T	6: 42,463,613 (GRCm39)	N171K	probably benign	Het
Or4f53	T	A	2: 111,087,497 (GRCm39)	F12L	probably damaging	Het
Or5d43	T	A	2: 88,105,223 (GRCm39)	M57L	probably damaging	Het
Or5g26	T	A	2: 85,494,622 (GRCm39)	D52V	probably damaging	Het
Or9s15	T	A	1: 92,524,720 (GRCm39)	C160S	probably benign	Het
Otogl	A	C	10: 107,737,197 (GRCm39)	C72W	probably damaging	Het
Pcdha11	T	A	18: 37,138,518 (GRCm39)	I49N	probably damaging	Het
Pcdha4	T	A	18: 37,087,008 (GRCm39)	L397*	probably null	Het
Pcdhb14	A	G	18: 37,581,331 (GRCm39)	S146G	probably benign	Het
Pclo	T	A	5: 14,725,829 (GRCm39)	H1562Q	unknown	Het
Pcsk9	T	C	4: 106,304,766 (GRCm39)	E434G	probably benign	Het
Phc2	A	G	4: 128,645,391 (GRCm39)	K833E	probably damaging	Het
Pja2	A	T	17: 64,599,857 (GRCm39)	S480R	probably damaging	Het
Pkd1	G	A	17: 24,797,070 (GRCm39)	G2493D	probably damaging	Het
Plk5	G	A	10: 80,195,138 (GRCm39)	V179M	possibly damaging	Het
Polr1a	G	A	6: 71,953,054 (GRCm39)	V1541I	probably benign	Het
Ppard	C	G	17: 28,505,348 (GRCm39)	R12G	unknown	Het
Ppp1r14a	A	G	7: 28,990,951 (GRCm39)	D73G	probably damaging	Het
Psd3	C	T	8: 68,573,800 (GRCm39)	R127H	probably benign	Het
Pten	G	T	19: 32,735,903 (GRCm39)	G20V	possibly damaging	Het
Ptprf	G	A	4: 118,067,526 (GRCm39)		probably benign	Het
Rad54l	T	C	4: 115,980,121 (GRCm39)	D21G	probably null	Het
Rgs14	T	C	13: 55,528,770 (GRCm39)	Y304H	probably damaging	Het
Rgs9	T	C	11: 109,131,694 (GRCm39)	K346R	probably damaging	Het
Rnf169	C	G	7: 99,575,653 (GRCm39)	G314A	probably damaging	Het
Rpgrip1l	T	A	8: 91,996,805 (GRCm39)	T692S	probably damaging	Het
Rtf1	T	C	2: 119,505,709 (GRCm39)	V54A	possibly damaging	Het
Rtn4	T	C	11: 29,658,660 (GRCm39)	V938A	probably benign	Het
Ryr2	T	C	13: 11,723,113 (GRCm39)	T2509A	probably damaging	Het
Ryr2	T	A	13: 11,702,818 (GRCm39)	D2890V	probably damaging	Het
Scel	A	C	14: 103,820,536 (GRCm39)	T348P	probably benign	Het
Scgb1b2	G	T	7: 30,990,998 (GRCm39)	L37I	possibly damaging	Het
Sdf4	A	G	4: 156,085,178 (GRCm39)	H171R	possibly damaging	Het
Sec31a	A	G	5: 100,541,222 (GRCm39)	V295A	probably damaging	Het
Semp2l2a	T	A	8: 13,886,970 (GRCm39)	I374F	possibly damaging	Het
Setx	T	A	2: 29,036,385 (GRCm39)	S957T	probably benign	Het
Shroom3	G	T	5: 93,090,945 (GRCm39)	V1151F	probably damaging	Het
Six5	A	G	7: 18,830,894 (GRCm39)	N507S	probably benign	Het
Slc12a7	T	C	13: 73,912,011 (GRCm39)		probably null	Het
Slc1a7	T	A	4: 107,850,237 (GRCm39)	V116E	probably damaging	Het
Slc22a1	A	G	17: 12,894,422 (GRCm39)	L42P	probably damaging	Het
Slc25a31	A	T	3: 40,675,975 (GRCm39)	I174F	probably damaging	Het
Slc31a2	A	T	4: 62,210,869 (GRCm39)	M3L	probably damaging	Het
Slco1a4	T	A	6: 141,791,223 (GRCm39)		probably benign	Het
Smcr8	C	T	11: 60,669,436 (GRCm39)		probably null	Het
Smg5	G	T	3: 88,262,999 (GRCm39)	E801*	probably null	Het
Smgc	C	A	15: 91,738,819 (GRCm39)	H492Q	probably benign	Het
Smyd4	G	T	11: 75,294,010 (GRCm39)	G694V	probably damaging	Het
Sorcs3	A	G	19: 48,387,183 (GRCm39)	T223A	possibly damaging	Het
Stab1	G	T	14: 30,863,328 (GRCm39)	C2119*	probably null	Het
Taar9	A	G	10: 23,984,741 (GRCm39)	I231T	probably damaging	Het
Tacr2	A	G	10: 62,097,327 (GRCm39)	Y269C	probably damaging	Het
Taf3	T	G	2: 9,955,934 (GRCm39)	K744N	possibly damaging	Het
Tarbp1	C	G	8: 127,201,628 (GRCm39)	E59D	possibly damaging	Het
Tcstv1b	T	A	13: 120,634,758 (GRCm39)	S13R	probably benign	Het
Tenm4	T	A	7: 96,555,452 (GRCm39)	V2682E	probably damaging	Het
Tet1	A	C	10: 62,658,442 (GRCm39)	L1468R	probably damaging	Het
Tgfb2	A	T	1: 186,361,110 (GRCm39)	Y380*	probably null	Het
Tgm5	T	G	2: 120,882,953 (GRCm39)	K435Q	probably damaging	Het
Themis	A	G	10: 28,637,507 (GRCm39)	T204A	probably benign	Het
Tm4sf1	T	C	3: 57,202,100 (GRCm39)	Y37C	probably damaging	Het
Tnn	T	C	1: 159,972,603 (GRCm39)	N333S	possibly damaging	Het
Tppp2	A	G	14: 52,156,805 (GRCm39)	N61D	probably benign	Het
Treml2	A	G	17: 48,616,187 (GRCm39)	T276A	probably benign	Het
Trit1	T	C	4: 122,910,431 (GRCm39)	V10A	probably benign	Het
Ttn	T	A	2: 76,794,990 (GRCm39)		probably benign	Het
Uba1y	T	G	Y: 825,890 (GRCm39)		probably null	Het
Vcam1	C	G	3: 115,909,584 (GRCm39)	G581A	probably damaging	Het
Vmn1r16	G	A	6: 57,300,175 (GRCm39)	T149I	probably benign	Het
Vmn1r209	T	C	13: 22,989,826 (GRCm39)	D288G	probably damaging	Het
Vmn1r78	T	A	7: 11,886,891 (GRCm39)	Y167*	probably null	Het
Vmn2r103	T	A	17: 20,015,338 (GRCm39)	S493T	probably benign	Het
Vmn2r105	T	A	17: 20,447,556 (GRCm39)	M423L	probably benign	Het
Vps13c	T	C	9: 67,871,564 (GRCm39)	F3244L	probably damaging	Het
Zfp119b	A	T	17: 56,246,642 (GRCm39)	D149E	probably damaging	Het
Zfp345	T	C	2: 150,315,228 (GRCm39)	Y103C	possibly damaging	Het
Zmym6	C	T	4: 127,017,009 (GRCm39)	T930I	probably benign	Het

Other mutations in Nav2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01097:Nav2	APN	7	49,220,942 (GRCm39)	missense	probably damaging	1.00
IGL01150:Nav2	APN	7	49,102,269 (GRCm39)	missense	probably benign	0.17
IGL01649:Nav2	APN	7	49,225,477 (GRCm39)	missense	probably damaging	1.00
IGL01662:Nav2	APN	7	49,220,957 (GRCm39)	missense	probably damaging	1.00
IGL02297:Nav2	APN	7	49,243,977 (GRCm39)	missense	probably damaging	0.98
IGL02313:Nav2	APN	7	49,208,521 (GRCm39)	missense	probably damaging	0.99
IGL02441:Nav2	APN	7	49,102,260 (GRCm39)	missense	probably damaging	1.00
IGL02472:Nav2	APN	7	49,195,789 (GRCm39)	missense	probably damaging	1.00
IGL02477:Nav2	APN	7	49,232,623 (GRCm39)	missense	probably damaging	0.99
IGL02725:Nav2	APN	7	49,214,843 (GRCm39)	missense	probably damaging	1.00
IGL02944:Nav2	APN	7	49,070,004 (GRCm39)	missense	probably damaging	0.99
IGL02953:Nav2	APN	7	49,198,171 (GRCm39)	missense	probably damaging	1.00
IGL03105:Nav2	APN	7	49,114,627 (GRCm39)	missense	probably damaging	1.00
IGL03234:Nav2	APN	7	49,111,756 (GRCm39)	missense	possibly damaging	0.94
IGL03274:Nav2	APN	7	49,011,847 (GRCm39)	missense	probably damaging	1.00
IGL03294:Nav2	APN	7	49,141,205 (GRCm39)	nonsense	probably null
R0006:Nav2	UTSW	7	49,102,978 (GRCm39)	missense	possibly damaging	0.50
R0070:Nav2	UTSW	7	49,220,462 (GRCm39)	missense	probably damaging	1.00
R0113:Nav2	UTSW	7	49,185,701 (GRCm39)	missense	probably damaging	1.00
R0306:Nav2	UTSW	7	49,195,651 (GRCm39)	missense	probably benign	0.01
R0346:Nav2	UTSW	7	49,254,333 (GRCm39)	missense	probably benign	0.11
R0539:Nav2	UTSW	7	49,111,686 (GRCm39)	missense	probably damaging	1.00
R0669:Nav2	UTSW	7	49,058,431 (GRCm39)	missense	probably damaging	1.00
R0785:Nav2	UTSW	7	49,070,081 (GRCm39)	missense	probably benign	0.06
R0970:Nav2	UTSW	7	49,233,901 (GRCm39)	missense	probably damaging	1.00
R1162:Nav2	UTSW	7	49,185,788 (GRCm39)	splice site	probably benign
R1274:Nav2	UTSW	7	49,254,178 (GRCm39)	nonsense	probably null
R1463:Nav2	UTSW	7	49,185,710 (GRCm39)	missense	probably damaging	1.00
R1464:Nav2	UTSW	7	49,011,952 (GRCm39)	missense	probably damaging	1.00
R1464:Nav2	UTSW	7	49,011,952 (GRCm39)	missense	probably damaging	1.00
R1536:Nav2	UTSW	7	49,195,682 (GRCm39)	missense	probably damaging	1.00
R1612:Nav2	UTSW	7	49,220,959 (GRCm39)	missense	probably damaging	1.00
R1638:Nav2	UTSW	7	49,102,213 (GRCm39)	missense	probably benign
R1731:Nav2	UTSW	7	49,197,922 (GRCm39)	missense	probably damaging	1.00
R1734:Nav2	UTSW	7	49,225,468 (GRCm39)	missense	probably damaging	1.00
R1865:Nav2	UTSW	7	49,197,943 (GRCm39)	missense	possibly damaging	0.95
R1945:Nav2	UTSW	7	49,114,620 (GRCm39)	missense	probably damaging	1.00
R1997:Nav2	UTSW	7	49,198,219 (GRCm39)	missense	probably benign	0.16
R2061:Nav2	UTSW	7	49,248,645 (GRCm39)	splice site	probably benign
R2117:Nav2	UTSW	7	49,114,328 (GRCm39)	missense	probably benign	0.00
R2174:Nav2	UTSW	7	49,102,411 (GRCm39)	missense	probably damaging	0.99
R2182:Nav2	UTSW	7	49,247,002 (GRCm39)	missense	probably benign	0.38
R2251:Nav2	UTSW	7	49,103,025 (GRCm39)	missense	probably damaging	1.00
R2283:Nav2	UTSW	7	49,141,152 (GRCm39)	missense	probably damaging	1.00
R2343:Nav2	UTSW	7	49,248,565 (GRCm39)	missense	possibly damaging	0.82
R2472:Nav2	UTSW	7	49,058,632 (GRCm39)	missense	probably benign
R2568:Nav2	UTSW	7	49,247,312 (GRCm39)	missense	probably damaging	1.00
R2656:Nav2	UTSW	7	49,195,690 (GRCm39)	missense	probably damaging	1.00
R2964:Nav2	UTSW	7	49,206,780 (GRCm39)	missense	probably damaging	1.00
R2966:Nav2	UTSW	7	49,206,780 (GRCm39)	missense	probably damaging	1.00
R3817:Nav2	UTSW	7	49,114,310 (GRCm39)	missense	probably benign	0.00
R3834:Nav2	UTSW	7	49,195,606 (GRCm39)	missense	possibly damaging	0.91
R4207:Nav2	UTSW	7	49,246,979 (GRCm39)	missense	probably damaging	1.00
R4207:Nav2	UTSW	7	49,222,046 (GRCm39)	splice site	probably null
R4411:Nav2	UTSW	7	49,047,857 (GRCm39)	missense	probably benign	0.37
R4413:Nav2	UTSW	7	49,047,857 (GRCm39)	missense	probably benign	0.37
R4440:Nav2	UTSW	7	49,225,011 (GRCm39)	splice site	probably benign
R4440:Nav2	UTSW	7	49,201,785 (GRCm39)	missense	possibly damaging	0.86
R4454:Nav2	UTSW	7	49,198,292 (GRCm39)	splice site	probably null
R4729:Nav2	UTSW	7	49,102,567 (GRCm39)	missense	probably benign	0.17
R4801:Nav2	UTSW	7	49,195,600 (GRCm39)	missense	possibly damaging	0.94
R4824:Nav2	UTSW	7	49,058,749 (GRCm39)	intron	probably benign
R4887:Nav2	UTSW	7	49,198,182 (GRCm39)	nonsense	probably null
R4908:Nav2	UTSW	7	49,254,258 (GRCm39)	missense	probably damaging	1.00
R4952:Nav2	UTSW	7	48,954,288 (GRCm39)	intron	probably benign
R4965:Nav2	UTSW	7	49,202,625 (GRCm39)	nonsense	probably null
R5169:Nav2	UTSW	7	49,198,231 (GRCm39)	nonsense	probably null
R5224:Nav2	UTSW	7	49,201,473 (GRCm39)	missense	probably benign	0.00
R5249:Nav2	UTSW	7	49,185,661 (GRCm39)	missense	probably damaging	1.00
R5285:Nav2	UTSW	7	49,197,982 (GRCm39)	missense	probably damaging	1.00
R5314:Nav2	UTSW	7	49,058,440 (GRCm39)	small deletion	probably benign
R5320:Nav2	UTSW	7	49,141,121 (GRCm39)	missense	probably benign	0.00
R5377:Nav2	UTSW	7	49,238,908 (GRCm39)	missense	probably benign	0.02
R5471:Nav2	UTSW	7	49,197,917 (GRCm39)	missense	probably damaging	1.00
R5754:Nav2	UTSW	7	49,206,794 (GRCm39)	missense	probably damaging	1.00
R5832:Nav2	UTSW	7	49,197,817 (GRCm39)	splice site	probably null
R5884:Nav2	UTSW	7	49,246,917 (GRCm39)	nonsense	probably null
R5921:Nav2	UTSW	7	48,954,324 (GRCm39)	intron	probably benign
R6180:Nav2	UTSW	7	49,107,915 (GRCm39)	missense	probably benign	0.39
R6208:Nav2	UTSW	7	49,213,851 (GRCm39)	missense	probably damaging	0.99
R6373:Nav2	UTSW	7	49,102,923 (GRCm39)	missense	probably damaging	1.00
R6450:Nav2	UTSW	7	49,244,114 (GRCm39)	missense	probably damaging	1.00
R6522:Nav2	UTSW	7	49,247,281 (GRCm39)	missense	probably damaging	1.00
R6626:Nav2	UTSW	7	49,244,100 (GRCm39)	missense	probably damaging	1.00
R6695:Nav2	UTSW	7	49,114,652 (GRCm39)	missense	probably benign	0.04
R6705:Nav2	UTSW	7	49,201,664 (GRCm39)	missense	probably damaging	1.00
R6842:Nav2	UTSW	7	49,107,917 (GRCm39)	missense	possibly damaging	0.91
R6847:Nav2	UTSW	7	49,141,204 (GRCm39)	missense	probably benign	0.14
R7287:Nav2	UTSW	7	49,070,076 (GRCm39)	missense	probably benign	0.01
R7312:Nav2	UTSW	7	49,111,672 (GRCm39)	missense	possibly damaging	0.55
R7315:Nav2	UTSW	7	49,198,037 (GRCm39)	missense	possibly damaging	0.61
R7337:Nav2	UTSW	7	49,201,521 (GRCm39)	missense	possibly damaging	0.56
R7366:Nav2	UTSW	7	49,203,951 (GRCm39)	splice site	probably null
R7451:Nav2	UTSW	7	49,202,577 (GRCm39)	splice site	probably null
R7545:Nav2	UTSW	7	49,232,605 (GRCm39)	missense	probably damaging	1.00
R7706:Nav2	UTSW	7	49,244,067 (GRCm39)	missense	probably benign	0.35
R7730:Nav2	UTSW	7	49,222,145 (GRCm39)	missense	probably damaging	1.00
R7812:Nav2	UTSW	7	49,246,921 (GRCm39)	missense	probably benign	0.13
R8097:Nav2	UTSW	7	49,237,525 (GRCm39)	missense	probably damaging	1.00
R8110:Nav2	UTSW	7	49,201,698 (GRCm39)	nonsense	probably null
R8119:Nav2	UTSW	7	49,103,232 (GRCm39)	missense	probably damaging	0.99
R8298:Nav2	UTSW	7	49,204,009 (GRCm39)	critical splice donor site	probably null
R8306:Nav2	UTSW	7	49,195,765 (GRCm39)	missense	probably benign	0.33
R8331:Nav2	UTSW	7	49,102,371 (GRCm39)	missense	probably benign
R8402:Nav2	UTSW	7	49,103,185 (GRCm39)	missense	probably benign	0.43
R8421:Nav2	UTSW	7	49,102,269 (GRCm39)	missense	probably benign
R8478:Nav2	UTSW	7	49,111,733 (GRCm39)	missense	probably damaging	0.99
R8724:Nav2	UTSW	7	49,141,184 (GRCm39)	missense	possibly damaging	0.82
R8753:Nav2	UTSW	7	49,102,320 (GRCm39)	missense	probably benign
R8835:Nav2	UTSW	7	49,248,551 (GRCm39)	missense	possibly damaging	0.83
R8933:Nav2	UTSW	7	49,111,705 (GRCm39)	missense	probably damaging	1.00
R8957:Nav2	UTSW	7	49,220,964 (GRCm39)	missense	probably damaging	1.00
R9069:Nav2	UTSW	7	49,208,561 (GRCm39)	missense	probably damaging	0.99
R9095:Nav2	UTSW	7	49,254,293 (GRCm39)	missense	probably damaging	1.00
R9223:Nav2	UTSW	7	49,202,599 (GRCm39)	missense	probably damaging	1.00
R9261:Nav2	UTSW	7	49,246,904 (GRCm39)	missense	probably damaging	1.00
X0023:Nav2	UTSW	7	49,197,647 (GRCm39)	missense	possibly damaging	0.47
Z1177:Nav2	UTSW	7	49,243,971 (GRCm39)	missense	probably benign	0.01
Z1177:Nav2	UTSW	7	49,102,509 (GRCm39)	missense	possibly damaging	0.47

Predicted Primers

Posted On

2017-04-14