Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00427:Dchs1'

5174

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dchs1

Ensembl Gene

ENSMUSG00000036862

Gene Name

dachsous cadherin related 1

Synonyms

C130033F22Rik, 3110041P15Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL00427

Quality Score

Status

Chromosome

Chromosomal Location

105402197-105436861 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 105407631 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 2067 (E2067G)

Ref Sequence

ENSEMBL: ENSMUSP00000077574 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078482]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000078482
AA Change: E2067G

PolyPhen 2 Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000077574
Gene: ENSMUSG00000036862
AA Change: E2067G

Domain	Start	End	E-Value	Type
signal peptide	1	36	N/A	INTRINSIC
CA	58	135	5.2e-11	SMART
CA	159	247	6.1e-17	SMART
CA	271	354	2.6e-30	SMART
CA	382	464	7.8e-26	SMART
CA	489	570	1.2e-34	SMART
CA	594	677	1.9e-27	SMART
CA	701	782	5.3e-11	SMART
CA	806	886	1e-12	SMART
CA	910	990	3.3e-14	SMART
CA	1016	1097	3.6e-18	SMART
CA	1121	1203	3.1e-34	SMART
CA	1233	1307	8.8e-16	SMART
low complexity region	1323	1335	N/A	INTRINSIC
CA	1344	1427	9.9e-9	SMART
CA	1451	1537	1.5e-23	SMART
CA	1560	1640	7.2e-32	SMART
CA	1664	1742	1.8e-31	SMART
CA	1765	1846	7.8e-30	SMART
CA	1870	1951	3.7e-26	SMART
low complexity region	1957	1965	N/A	INTRINSIC
CA	1979	2059	1.1e-6	SMART
CA	2083	2162	2.7e-18	SMART
CA	2186	2268	2.2e-26	SMART
CA	2291	2367	1e-18	SMART
CA	2391	2473	1.8e-23	SMART
CA	2497	2593	3.5e-21	SMART
CA	2617	2697	1.2e-25	SMART
CA	2721	2804	1.9e-18	SMART
CA	2828	2919	3e-3	SMART
transmembrane domain	2932	2954	N/A	INTRINSIC
low complexity region	3001	3017	N/A	INTRINSIC
low complexity region	3046	3055	N/A	INTRINSIC
low complexity region	3088	3097	N/A	INTRINSIC
low complexity region	3185	3196	N/A	INTRINSIC
low complexity region	3237	3259	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000131504

Predicted Effect

probably benign
Transcript: ENSMUST00000140959

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit postnatal lethality, growth retardation, small lungs, abnormal cochlea morphology, abnormal kidney morphology, cardiovascular abnormalities and skeletal abnormalities. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adcy3	A	G	12: 4,244,357 (GRCm39)	D289G	probably damaging	Het
Adnp	C	T	2: 168,024,482 (GRCm39)	D938N	probably benign	Het
Arpin	T	A	7: 79,577,423 (GRCm39)	N208I	probably benign	Het
Cby3	A	G	11: 50,248,638 (GRCm39)		probably benign	Het
Cmklr2	A	T	1: 63,222,497 (GRCm39)	I246N	probably damaging	Het
Cnih4	T	A	1: 180,981,312 (GRCm39)	S28T	probably damaging	Het
D130052B06Rik	G	T	11: 33,573,558 (GRCm39)	V97L	possibly damaging	Het
Dennd6a	C	T	14: 26,329,768 (GRCm39)	T113I	probably damaging	Het
Dock4	T	A	12: 40,882,305 (GRCm39)	F1590L	possibly damaging	Het
Dop1a	G	T	9: 86,403,553 (GRCm39)	Q1582H	probably benign	Het
Dop1a	A	T	9: 86,403,552 (GRCm39)	Q1582L	probably damaging	Het
Dop1a	C	A	9: 86,403,551 (GRCm39)	Q1582K	possibly damaging	Het
Ebna1bp2	A	T	4: 118,483,018 (GRCm39)	K291M	probably damaging	Het
Evpl	G	T	11: 116,125,331 (GRCm39)	Q73K	probably benign	Het
Fam131b	G	T	6: 42,295,895 (GRCm39)	T139K	probably damaging	Het
Golga3	A	G	5: 110,368,753 (GRCm39)	T1358A	probably damaging	Het
Hgf	G	A	5: 16,783,484 (GRCm39)	D265N	probably benign	Het
Homer1	A	G	13: 93,538,622 (GRCm39)	N333S	probably benign	Het
Igkv17-134	A	T	6: 67,697,968 (GRCm39)		probably benign	Het
Il16	T	C	7: 83,301,666 (GRCm39)	D152G	probably benign	Het
Ireb2	T	C	9: 54,806,766 (GRCm39)		probably benign	Het
Itgb2	C	T	10: 77,393,790 (GRCm39)	T410I	probably benign	Het
Kctd14	C	A	7: 97,106,919 (GRCm39)	A111E	possibly damaging	Het
Lmod3	A	C	6: 97,229,258 (GRCm39)	V92G	probably damaging	Het
Lmtk2	A	G	5: 144,070,973 (GRCm39)	D83G	probably damaging	Het
Myh1	A	G	11: 67,111,691 (GRCm39)	E1682G	probably damaging	Het
Myo9a	T	A	9: 59,750,342 (GRCm39)		probably benign	Het
Nlrc4	T	C	17: 74,754,087 (GRCm39)	N99D	probably benign	Het
P2rx3	A	G	2: 84,865,616 (GRCm39)	Y10H	probably damaging	Het
Pcsk7	C	A	9: 45,838,958 (GRCm39)	D623E	probably benign	Het
Plxna1	A	G	6: 89,297,980 (GRCm39)	I1766T	probably damaging	Het
Ptk7	T	C	17: 46,885,353 (GRCm39)	Y691C	probably damaging	Het
Rec8	A	T	14: 55,856,108 (GRCm39)	T17S	probably damaging	Het
Rtraf-ps	A	C	3: 88,484,230 (GRCm39)		probably benign	Het
Ryr1	T	C	7: 28,804,162 (GRCm39)		probably benign	Het
Scg3	T	G	9: 75,570,519 (GRCm39)	K345T	probably damaging	Het
Serpina3b	A	T	12: 104,099,200 (GRCm39)	K238N	probably benign	Het
Slc38a9	T	A	13: 112,838,152 (GRCm39)	S306T	probably damaging	Het
Txndc16	A	G	14: 45,382,547 (GRCm39)		probably benign	Het
Vmn1r238	T	A	18: 3,123,243 (GRCm39)	Y57F	probably benign	Het
Vmn2r104	A	T	17: 20,258,501 (GRCm39)	S548T	probably damaging	Het
Xrcc1	T	A	7: 24,247,309 (GRCm39)		probably null	Het

Other mutations in Dchs1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00235:Dchs1	APN	7	105,407,950 (GRCm39)	missense	probably damaging	1.00
IGL00422:Dchs1	APN	7	105,407,236 (GRCm39)	missense	possibly damaging	0.88
IGL00469:Dchs1	APN	7	105,404,468 (GRCm39)	missense	probably damaging	1.00
IGL00470:Dchs1	APN	7	105,407,414 (GRCm39)	missense	probably damaging	1.00
IGL00534:Dchs1	APN	7	105,407,150 (GRCm39)	missense	probably benign
IGL01292:Dchs1	APN	7	105,410,098 (GRCm39)	missense	probably damaging	0.98
IGL01380:Dchs1	APN	7	105,411,418 (GRCm39)	missense	probably damaging	1.00
IGL01396:Dchs1	APN	7	105,421,490 (GRCm39)	missense	probably damaging	1.00
IGL01448:Dchs1	APN	7	105,421,134 (GRCm39)	missense	probably damaging	0.98
IGL01759:Dchs1	APN	7	105,404,509 (GRCm39)	missense	probably benign	0.00
IGL01829:Dchs1	APN	7	105,404,604 (GRCm39)	missense	probably damaging	0.99
IGL01946:Dchs1	APN	7	105,408,312 (GRCm39)	missense	probably damaging	1.00
IGL01955:Dchs1	APN	7	105,406,798 (GRCm39)	missense	probably benign	0.00
IGL02012:Dchs1	APN	7	105,413,504 (GRCm39)	missense	probably damaging	0.98
IGL02222:Dchs1	APN	7	105,414,094 (GRCm39)	missense	probably damaging	1.00
IGL02261:Dchs1	APN	7	105,421,776 (GRCm39)	missense	probably damaging	1.00
IGL02365:Dchs1	APN	7	105,404,395 (GRCm39)	missense	probably benign	0.22
IGL02430:Dchs1	APN	7	105,421,178 (GRCm39)	missense	probably benign	0.34
IGL02500:Dchs1	APN	7	105,405,013 (GRCm39)	missense	probably benign
IGL02741:Dchs1	APN	7	105,406,530 (GRCm39)	missense	probably damaging	1.00
IGL02890:Dchs1	APN	7	105,405,698 (GRCm39)	missense	probably damaging	1.00
IGL03213:Dchs1	APN	7	105,404,279 (GRCm39)	missense	probably damaging	1.00
G1patch:Dchs1	UTSW	7	105,408,000 (GRCm39)	missense	probably damaging	0.99
P0026:Dchs1	UTSW	7	105,407,612 (GRCm39)	missense	probably damaging	0.99
PIT4377001:Dchs1	UTSW	7	105,406,795 (GRCm39)	missense	probably damaging	1.00
PIT4791001:Dchs1	UTSW	7	105,408,178 (GRCm39)	missense	probably damaging	1.00
R0013:Dchs1	UTSW	7	105,405,043 (GRCm39)	missense	possibly damaging	0.90
R0090:Dchs1	UTSW	7	105,405,139 (GRCm39)	missense	probably benign	0.18
R0091:Dchs1	UTSW	7	105,415,301 (GRCm39)	splice site	probably benign
R0193:Dchs1	UTSW	7	105,414,190 (GRCm39)	missense	probably benign	0.40
R0395:Dchs1	UTSW	7	105,407,745 (GRCm39)	missense	probably damaging	1.00
R0448:Dchs1	UTSW	7	105,415,134 (GRCm39)	missense	probably benign	0.00
R0480:Dchs1	UTSW	7	105,420,696 (GRCm39)	missense	probably benign	0.14
R0485:Dchs1	UTSW	7	105,421,934 (GRCm39)	missense	probably benign	0.00
R0566:Dchs1	UTSW	7	105,408,402 (GRCm39)	missense	probably benign	0.00
R0571:Dchs1	UTSW	7	105,421,203 (GRCm39)	missense	probably damaging	1.00
R0573:Dchs1	UTSW	7	105,407,985 (GRCm39)	missense	probably damaging	0.98
R0577:Dchs1	UTSW	7	105,413,462 (GRCm39)	missense	possibly damaging	0.78
R0622:Dchs1	UTSW	7	105,412,656 (GRCm39)	missense	probably damaging	1.00
R0654:Dchs1	UTSW	7	105,421,556 (GRCm39)	missense	probably damaging	1.00
R0677:Dchs1	UTSW	7	105,414,191 (GRCm39)	missense	probably damaging	1.00
R1171:Dchs1	UTSW	7	105,406,921 (GRCm39)	missense	probably benign
R1241:Dchs1	UTSW	7	105,407,385 (GRCm39)	missense	probably damaging	1.00
R1389:Dchs1	UTSW	7	105,404,778 (GRCm39)	missense	probably benign	0.40
R1427:Dchs1	UTSW	7	105,415,398 (GRCm39)	missense	probably benign	0.06
R1458:Dchs1	UTSW	7	105,404,451 (GRCm39)	missense	probably damaging	1.00
R1513:Dchs1	UTSW	7	105,421,278 (GRCm39)	nonsense	probably null
R1524:Dchs1	UTSW	7	105,413,732 (GRCm39)	missense	probably damaging	1.00
R1525:Dchs1	UTSW	7	105,408,138 (GRCm39)	missense	probably damaging	1.00
R1534:Dchs1	UTSW	7	105,421,247 (GRCm39)	missense	probably damaging	0.98
R1567:Dchs1	UTSW	7	105,421,068 (GRCm39)	missense	probably benign	0.01
R1577:Dchs1	UTSW	7	105,415,162 (GRCm39)	missense	probably damaging	1.00
R1603:Dchs1	UTSW	7	105,411,977 (GRCm39)	missense	probably benign	0.24
R1676:Dchs1	UTSW	7	105,404,128 (GRCm39)	missense	probably benign	0.40
R1794:Dchs1	UTSW	7	105,420,927 (GRCm39)	missense	probably benign	0.02
R1826:Dchs1	UTSW	7	105,406,834 (GRCm39)	missense	probably damaging	1.00
R1892:Dchs1	UTSW	7	105,413,363 (GRCm39)	missense	probably benign	0.00
R1924:Dchs1	UTSW	7	105,421,487 (GRCm39)	missense	possibly damaging	0.81
R1932:Dchs1	UTSW	7	105,415,109 (GRCm39)	missense	probably damaging	1.00
R1962:Dchs1	UTSW	7	105,413,408 (GRCm39)	missense	probably damaging	1.00
R1985:Dchs1	UTSW	7	105,421,605 (GRCm39)	missense	possibly damaging	0.72
R1993:Dchs1	UTSW	7	105,411,755 (GRCm39)	missense	probably benign	0.00
R2007:Dchs1	UTSW	7	105,404,532 (GRCm39)	missense	probably damaging	1.00
R2316:Dchs1	UTSW	7	105,413,411 (GRCm39)	missense	possibly damaging	0.71
R2351:Dchs1	UTSW	7	105,403,301 (GRCm39)	missense	probably benign
R2474:Dchs1	UTSW	7	105,422,045 (GRCm39)	missense	probably damaging	1.00
R2474:Dchs1	UTSW	7	105,404,281 (GRCm39)	missense	probably benign	0.37
R3429:Dchs1	UTSW	7	105,405,711 (GRCm39)	missense	possibly damaging	0.85
R3430:Dchs1	UTSW	7	105,405,711 (GRCm39)	missense	possibly damaging	0.85
R3737:Dchs1	UTSW	7	105,411,523 (GRCm39)	missense	possibly damaging	0.88
R3767:Dchs1	UTSW	7	105,406,292 (GRCm39)	missense	possibly damaging	0.67
R3874:Dchs1	UTSW	7	105,410,842 (GRCm39)	missense	probably damaging	1.00
R3883:Dchs1	UTSW	7	105,411,770 (GRCm39)	missense	probably damaging	1.00
R4105:Dchs1	UTSW	7	105,414,347 (GRCm39)	missense	probably damaging	1.00
R4209:Dchs1	UTSW	7	105,415,397 (GRCm39)	missense	probably damaging	0.99
R4329:Dchs1	UTSW	7	105,402,966 (GRCm39)	missense	probably damaging	1.00
R4516:Dchs1	UTSW	7	105,404,059 (GRCm39)	missense	probably damaging	1.00
R4579:Dchs1	UTSW	7	105,408,180 (GRCm39)	missense	probably benign
R4579:Dchs1	UTSW	7	105,403,972 (GRCm39)	missense	probably damaging	1.00
R4588:Dchs1	UTSW	7	105,405,248 (GRCm39)	missense	probably benign
R4613:Dchs1	UTSW	7	105,421,931 (GRCm39)	missense	probably damaging	1.00
R4632:Dchs1	UTSW	7	105,403,562 (GRCm39)	missense	probably benign	0.02
R4696:Dchs1	UTSW	7	105,413,834 (GRCm39)	missense	probably damaging	1.00
R4725:Dchs1	UTSW	7	105,414,759 (GRCm39)	missense	probably damaging	1.00
R4725:Dchs1	UTSW	7	105,404,460 (GRCm39)	missense	probably damaging	0.98
R4738:Dchs1	UTSW	7	105,407,880 (GRCm39)	missense	probably damaging	0.96
R4768:Dchs1	UTSW	7	105,420,827 (GRCm39)	missense	possibly damaging	0.96
R4784:Dchs1	UTSW	7	105,415,133 (GRCm39)	missense	probably damaging	1.00
R4864:Dchs1	UTSW	7	105,404,460 (GRCm39)	missense	probably damaging	0.98
R4880:Dchs1	UTSW	7	105,404,937 (GRCm39)	missense	probably benign	0.00
R4909:Dchs1	UTSW	7	105,415,462 (GRCm39)	missense	probably damaging	1.00
R5102:Dchs1	UTSW	7	105,421,384 (GRCm39)	missense	probably benign	0.09
R5109:Dchs1	UTSW	7	105,414,221 (GRCm39)	missense	probably benign
R5126:Dchs1	UTSW	7	105,402,724 (GRCm39)	missense	probably damaging	1.00
R5149:Dchs1	UTSW	7	105,404,865 (GRCm39)	missense	probably damaging	0.98
R5330:Dchs1	UTSW	7	105,403,809 (GRCm39)	missense	probably damaging	1.00
R5384:Dchs1	UTSW	7	105,421,262 (GRCm39)	missense	probably damaging	1.00
R5384:Dchs1	UTSW	7	105,407,236 (GRCm39)	missense	probably damaging	1.00
R5386:Dchs1	UTSW	7	105,407,236 (GRCm39)	missense	probably damaging	1.00
R5622:Dchs1	UTSW	7	105,404,500 (GRCm39)	missense	probably benign	0.11
R5623:Dchs1	UTSW	7	105,421,976 (GRCm39)	missense	probably damaging	1.00
R5708:Dchs1	UTSW	7	105,422,016 (GRCm39)	missense	probably damaging	1.00
R5718:Dchs1	UTSW	7	105,404,955 (GRCm39)	missense	probably benign	0.01
R5743:Dchs1	UTSW	7	105,420,803 (GRCm39)	missense	probably benign
R5759:Dchs1	UTSW	7	105,413,383 (GRCm39)	missense	probably damaging	0.99
R5772:Dchs1	UTSW	7	105,422,247 (GRCm39)	missense	probably damaging	1.00
R5860:Dchs1	UTSW	7	105,421,242 (GRCm39)	missense	probably damaging	1.00
R5916:Dchs1	UTSW	7	105,408,373 (GRCm39)	missense	probably damaging	1.00
R5965:Dchs1	UTSW	7	105,405,132 (GRCm39)	missense	probably damaging	1.00
R5997:Dchs1	UTSW	7	105,403,302 (GRCm39)	missense	probably benign	0.08
R6065:Dchs1	UTSW	7	105,404,628 (GRCm39)	missense	probably damaging	1.00
R6136:Dchs1	UTSW	7	105,410,132 (GRCm39)	missense	probably benign
R6137:Dchs1	UTSW	7	105,414,313 (GRCm39)	missense	probably damaging	0.99
R6324:Dchs1	UTSW	7	105,414,145 (GRCm39)	missense	probably benign	0.05
R6363:Dchs1	UTSW	7	105,407,679 (GRCm39)	missense	probably benign	0.12
R6466:Dchs1	UTSW	7	105,413,748 (GRCm39)	missense	probably benign	0.09
R6544:Dchs1	UTSW	7	105,407,385 (GRCm39)	missense	probably damaging	1.00
R6572:Dchs1	UTSW	7	105,408,013 (GRCm39)	missense	possibly damaging	0.94
R6579:Dchs1	UTSW	7	105,412,120 (GRCm39)	missense	probably benign	0.17
R6632:Dchs1	UTSW	7	105,411,085 (GRCm39)	missense	probably damaging	1.00
R6725:Dchs1	UTSW	7	105,408,000 (GRCm39)	missense	probably damaging	0.99
R6789:Dchs1	UTSW	7	105,406,210 (GRCm39)	missense	possibly damaging	0.61
R6868:Dchs1	UTSW	7	105,412,710 (GRCm39)	missense	possibly damaging	0.91
R7058:Dchs1	UTSW	7	105,406,228 (GRCm39)	missense	probably benign
R7064:Dchs1	UTSW	7	105,412,392 (GRCm39)	missense	probably damaging	0.99
R7076:Dchs1	UTSW	7	105,411,078 (GRCm39)	missense	probably benign	0.04
R7191:Dchs1	UTSW	7	105,414,646 (GRCm39)	missense	possibly damaging	0.89
R7298:Dchs1	UTSW	7	105,404,338 (GRCm39)	nonsense	probably null
R7380:Dchs1	UTSW	7	105,407,835 (GRCm39)	missense	probably benign	0.35
R7438:Dchs1	UTSW	7	105,404,155 (GRCm39)	missense	probably benign	0.30
R7496:Dchs1	UTSW	7	105,411,066 (GRCm39)	missense	probably damaging	1.00
R7534:Dchs1	UTSW	7	105,421,580 (GRCm39)	missense	probably benign	0.00
R7604:Dchs1	UTSW	7	105,415,189 (GRCm39)	missense	probably damaging	1.00
R7631:Dchs1	UTSW	7	105,408,445 (GRCm39)	missense	probably benign
R7821:Dchs1	UTSW	7	105,414,352 (GRCm39)	missense	probably benign	0.00
R7834:Dchs1	UTSW	7	105,414,774 (GRCm39)	missense	probably benign	0.39
R7841:Dchs1	UTSW	7	105,412,180 (GRCm39)	missense	probably benign
R7913:Dchs1	UTSW	7	105,408,435 (GRCm39)	missense	possibly damaging	0.61
R8041:Dchs1	UTSW	7	105,404,395 (GRCm39)	missense	probably benign	0.45
R8076:Dchs1	UTSW	7	105,411,189 (GRCm39)	missense	probably damaging	1.00
R8076:Dchs1	UTSW	7	105,405,128 (GRCm39)	missense	possibly damaging	0.52
R8087:Dchs1	UTSW	7	105,402,706 (GRCm39)	missense	probably benign	0.41
R8125:Dchs1	UTSW	7	105,414,089 (GRCm39)	missense	possibly damaging	0.91
R8223:Dchs1	UTSW	7	105,411,824 (GRCm39)	missense	possibly damaging	0.81
R8239:Dchs1	UTSW	7	105,414,718 (GRCm39)	missense	probably benign	0.22
R8476:Dchs1	UTSW	7	105,408,015 (GRCm39)	missense	probably benign	0.05
R8497:Dchs1	UTSW	7	105,408,168 (GRCm39)	missense	probably damaging	1.00
R8770:Dchs1	UTSW	7	105,420,945 (GRCm39)	missense	probably damaging	1.00
R8856:Dchs1	UTSW	7	105,410,064 (GRCm39)	missense	probably damaging	1.00
R8866:Dchs1	UTSW	7	105,404,597 (GRCm39)	missense	probably benign	0.00
R8948:Dchs1	UTSW	7	105,408,212 (GRCm39)	missense	probably benign	0.30
R8950:Dchs1	UTSW	7	105,408,212 (GRCm39)	missense	probably benign	0.30
R9029:Dchs1	UTSW	7	105,402,919 (GRCm39)	missense	probably benign	0.13
R9039:Dchs1	UTSW	7	105,405,215 (GRCm39)	missense	probably benign	0.11
R9081:Dchs1	UTSW	7	105,403,636 (GRCm39)	missense	probably benign	0.00
R9134:Dchs1	UTSW	7	105,404,910 (GRCm39)	missense	probably damaging	0.96
R9159:Dchs1	UTSW	7	105,415,126 (GRCm39)	missense	probably benign
R9162:Dchs1	UTSW	7	105,414,732 (GRCm39)	missense	probably damaging	1.00
R9169:Dchs1	UTSW	7	105,422,114 (GRCm39)	missense	probably damaging	1.00
R9262:Dchs1	UTSW	7	105,404,833 (GRCm39)	missense	probably damaging	1.00
R9292:Dchs1	UTSW	7	105,403,120 (GRCm39)	missense	probably damaging	1.00
R9325:Dchs1	UTSW	7	105,415,402 (GRCm39)	missense	possibly damaging	0.51
R9376:Dchs1	UTSW	7	105,414,981 (GRCm39)	critical splice donor site	probably null
R9392:Dchs1	UTSW	7	105,421,869 (GRCm39)	missense	probably benign	0.09
R9619:Dchs1	UTSW	7	105,413,662 (GRCm39)	missense	probably benign	0.07
R9680:Dchs1	UTSW	7	105,411,625 (GRCm39)	missense	probably damaging	1.00
R9687:Dchs1	UTSW	7	105,407,191 (GRCm39)	missense	probably damaging	0.99
R9747:Dchs1	UTSW	7	105,412,682 (GRCm39)	missense	probably damaging	1.00
Z1177:Dchs1	UTSW	7	105,406,900 (GRCm39)	missense	probably damaging	1.00
Z1177:Dchs1	UTSW	7	105,407,758 (GRCm39)	missense	probably benign	0.00

Posted On

2012-04-20