Incidental Mutation 'R7392:Arap2'
| ID |
573500 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arap2
|
| Ensembl Gene |
ENSMUSG00000037999 |
| Gene Name |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| Synonyms |
Centd1 |
| MMRRC Submission |
045474-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7392 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
62759788-62923502 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 62855728 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 569
(S569R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075924
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000076623]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000076623
AA Change: S569R
PolyPhen 2
Score 0.539 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000075924
Gene: ENSMUSG00000037999
AA Change: S569R
| Domain | Start | End | E-Value | Type |
|---|
|
SAM
|
3 |
70 |
3.69e-7 |
SMART |
|
low complexity region
|
222 |
233 |
N/A |
INTRINSIC |
|
PH
|
481 |
574 |
6.45e-17 |
SMART |
|
PH
|
586 |
679 |
9.05e-12 |
SMART |
|
ArfGap
|
684 |
805 |
9.2e-33 |
SMART |
|
PH
|
891 |
1003 |
1.51e-8 |
SMART |
|
PH
|
1013 |
1112 |
9.21e-4 |
SMART |
|
RhoGAP
|
1124 |
1300 |
1.36e-50 |
SMART |
|
Pfam:RA
|
1325 |
1416 |
2.1e-7 |
PFAM |
|
PH
|
1429 |
1533 |
2.68e-14 |
SMART |
|
coiled coil region
|
1561 |
1590 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
A |
7: 41,275,990 (GRCm39) |
F564L |
probably damaging |
Het |
| Abcc2 |
T |
C |
19: 43,797,126 (GRCm39) |
I499T |
probably damaging |
Het |
| Adamts13 |
C |
T |
2: 26,879,336 (GRCm39) |
R630C |
probably damaging |
Het |
| Adgrv1 |
A |
T |
13: 81,708,808 (GRCm39) |
F1199I |
probably damaging |
Het |
| Agbl5 |
G |
A |
5: 31,048,115 (GRCm39) |
|
probably null |
Het |
| Anks1b |
A |
G |
10: 90,516,648 (GRCm39) |
D881G |
possibly damaging |
Het |
| Arhgap15 |
T |
C |
2: 43,953,786 (GRCm39) |
S171P |
possibly damaging |
Het |
| Arhgef11 |
G |
A |
3: 87,624,482 (GRCm39) |
|
probably null |
Het |
| Baz1a |
C |
A |
12: 54,945,550 (GRCm39) |
L1271F |
probably damaging |
Het |
| Bdnf |
A |
C |
2: 109,554,275 (GRCm39) |
K216N |
probably benign |
Het |
| Bmp7 |
C |
T |
2: 172,711,998 (GRCm39) |
D409N |
probably damaging |
Het |
| Bnip5 |
A |
T |
17: 29,127,351 (GRCm39) |
D219E |
probably benign |
Het |
| Cacna1c |
T |
A |
6: 118,718,881 (GRCm39) |
I390F |
|
Het |
| Chd8 |
A |
G |
14: 52,470,312 (GRCm39) |
S433P |
probably benign |
Het |
| Clrn2 |
A |
G |
5: 45,621,251 (GRCm39) |
E215G |
possibly damaging |
Het |
| Col19a1 |
T |
G |
1: 24,573,115 (GRCm39) |
D219A |
unknown |
Het |
| Col2a1 |
G |
A |
15: 97,878,032 (GRCm39) |
R1036* |
probably null |
Het |
| Copg1 |
T |
A |
6: 87,867,257 (GRCm39) |
V110D |
probably benign |
Het |
| Cpd |
C |
T |
11: 76,692,605 (GRCm39) |
G744D |
probably damaging |
Het |
| Crygs |
G |
A |
16: 22,625,252 (GRCm39) |
P63L |
probably benign |
Het |
| Dcn |
A |
G |
10: 97,345,860 (GRCm39) |
D224G |
probably damaging |
Het |
| Dnah7a |
T |
C |
1: 53,540,820 (GRCm39) |
E2518G |
probably benign |
Het |
| Efcab6 |
C |
A |
15: 83,873,152 (GRCm39) |
R197L |
probably benign |
Het |
| Efr3b |
T |
A |
12: 4,019,588 (GRCm39) |
Y723F |
probably benign |
Het |
| Enam |
A |
G |
5: 88,649,523 (GRCm39) |
N344S |
probably damaging |
Het |
| Erich4 |
A |
G |
7: 25,315,101 (GRCm39) |
I58T |
possibly damaging |
Het |
| Esrp1 |
A |
G |
4: 11,338,809 (GRCm39) |
V665A |
probably benign |
Het |
| Etf1 |
G |
A |
18: 35,039,103 (GRCm39) |
T388I |
probably benign |
Het |
| Faf1 |
A |
G |
4: 109,652,040 (GRCm39) |
T244A |
probably benign |
Het |
| Fbn1 |
T |
C |
2: 125,185,844 (GRCm39) |
D1610G |
probably damaging |
Het |
| Fcgbpl1 |
C |
T |
7: 27,863,797 (GRCm39) |
T2523M |
possibly damaging |
Het |
| Frem1 |
G |
T |
4: 82,932,064 (GRCm39) |
F212L |
probably benign |
Het |
| Fuom |
T |
A |
7: 139,681,073 (GRCm39) |
D85V |
probably damaging |
Het |
| Gcfc2 |
T |
C |
6: 81,919,993 (GRCm39) |
|
probably null |
Het |
| Gpr37 |
C |
T |
6: 25,688,786 (GRCm39) |
A104T |
probably benign |
Het |
| Hsp90ab1 |
G |
C |
17: 45,879,974 (GRCm39) |
T514S |
probably benign |
Het |
| Ifnl2 |
A |
G |
7: 28,209,094 (GRCm39) |
F74L |
probably benign |
Het |
| Ipo11 |
G |
A |
13: 107,028,199 (GRCm39) |
R367* |
probably null |
Het |
| Itpr2 |
T |
C |
6: 146,260,838 (GRCm39) |
D963G |
possibly damaging |
Het |
| Krt15 |
A |
T |
11: 100,026,386 (GRCm39) |
V100E |
possibly damaging |
Het |
| Lrch3 |
T |
A |
16: 32,807,125 (GRCm39) |
L466* |
probably null |
Het |
| Lrfn5 |
A |
T |
12: 61,887,090 (GRCm39) |
T293S |
probably benign |
Het |
| Lrp5 |
A |
G |
19: 3,660,199 (GRCm39) |
I955T |
probably damaging |
Het |
| Lrrc4b |
C |
T |
7: 44,111,439 (GRCm39) |
T437M |
probably damaging |
Het |
| Man1a |
A |
G |
10: 53,795,283 (GRCm39) |
Y657H |
probably damaging |
Het |
| Mapkap1 |
G |
T |
2: 34,325,166 (GRCm39) |
R94L |
probably damaging |
Het |
| Mtmr4 |
T |
A |
11: 87,495,383 (GRCm39) |
L480Q |
probably damaging |
Het |
| Mycbp2 |
T |
C |
14: 103,389,627 (GRCm39) |
I3504M |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,480,564 (GRCm39) |
C1169S |
probably damaging |
Het |
| Myo15a |
T |
C |
11: 60,396,802 (GRCm39) |
S1455P |
|
Het |
| Niban1 |
A |
G |
1: 151,571,975 (GRCm39) |
T307A |
probably damaging |
Het |
| Nid2 |
A |
G |
14: 19,818,724 (GRCm39) |
D406G |
probably benign |
Het |
| Nrip2 |
A |
G |
6: 128,381,913 (GRCm39) |
I69V |
probably benign |
Het |
| Nthl1 |
G |
A |
17: 24,857,598 (GRCm39) |
V266I |
probably benign |
Het |
| Or2ag16 |
T |
C |
7: 106,352,589 (GRCm39) |
E2G |
possibly damaging |
Het |
| Or5an6 |
G |
T |
19: 12,371,829 (GRCm39) |
L67F |
probably damaging |
Het |
| Or5b21 |
A |
G |
19: 12,839,951 (GRCm39) |
T271A |
probably benign |
Het |
| Or5g23 |
A |
C |
2: 85,438,832 (GRCm39) |
C141G |
possibly damaging |
Het |
| Or5p75-ps1 |
C |
A |
7: 108,107,291 (GRCm39) |
H9Q |
possibly damaging |
Het |
| Or8k25 |
A |
G |
2: 86,243,496 (GRCm39) |
V300A |
probably benign |
Het |
| Or8s5 |
A |
G |
15: 98,238,192 (GRCm39) |
V226A |
probably benign |
Het |
| Pcdhb1 |
A |
C |
18: 37,398,171 (GRCm39) |
S41R |
possibly damaging |
Het |
| Pdcd11 |
T |
A |
19: 47,116,436 (GRCm39) |
F1529I |
probably damaging |
Het |
| Plcd3 |
C |
A |
11: 102,992,383 (GRCm39) |
|
probably benign |
Het |
| Qdpr |
T |
C |
5: 45,596,718 (GRCm39) |
M149V |
probably benign |
Het |
| R3hcc1 |
T |
A |
14: 69,943,329 (GRCm39) |
|
probably null |
Het |
| Rasgrf2 |
T |
C |
13: 92,041,856 (GRCm39) |
Y392C |
|
Het |
| Slc8a3 |
A |
C |
12: 81,361,577 (GRCm39) |
V414G |
probably damaging |
Het |
| Slco1a6 |
A |
G |
6: 142,103,003 (GRCm39) |
S54P |
probably benign |
Het |
| Sos1 |
C |
A |
17: 80,731,629 (GRCm39) |
V624F |
probably damaging |
Het |
| Spdef |
T |
C |
17: 27,936,262 (GRCm39) |
D227G |
probably benign |
Het |
| Sptb |
G |
T |
12: 76,671,003 (GRCm39) |
Q447K |
probably damaging |
Het |
| Srsf12 |
A |
T |
4: 33,209,265 (GRCm39) |
R62W |
unknown |
Het |
| Stag3 |
T |
C |
5: 138,289,628 (GRCm39) |
L266P |
probably damaging |
Het |
| Sult2b1 |
T |
C |
7: 45,391,862 (GRCm39) |
|
probably benign |
Het |
| Taf1a |
A |
G |
1: 183,190,095 (GRCm39) |
T66A |
|
Het |
| Tfg |
A |
T |
16: 56,532,972 (GRCm39) |
|
probably null |
Het |
| Trim34b |
A |
G |
7: 103,985,604 (GRCm39) |
N413S |
probably benign |
Het |
| Txndc15 |
T |
A |
13: 55,869,399 (GRCm39) |
M184K |
probably damaging |
Het |
| Umodl1 |
A |
C |
17: 31,201,306 (GRCm39) |
S412R |
probably damaging |
Het |
| Zbtb8b |
T |
A |
4: 129,326,683 (GRCm39) |
M161L |
probably benign |
Het |
| Zfp597 |
A |
T |
16: 3,684,369 (GRCm39) |
V129E |
probably benign |
Het |
| Zfp790 |
T |
C |
7: 29,528,050 (GRCm39) |
I245T |
possibly damaging |
Het |
|
| Other mutations in Arap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00481:Arap2
|
APN |
5 |
62,793,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00642:Arap2
|
APN |
5 |
62,890,401 (GRCm39) |
nonsense |
probably null |
|
|
IGL00705:Arap2
|
APN |
5 |
62,835,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00942:Arap2
|
APN |
5 |
62,855,732 (GRCm39) |
nonsense |
probably null |
|
|
IGL01069:Arap2
|
APN |
5 |
62,807,199 (GRCm39) |
missense |
probably benign |
|
|
IGL01601:Arap2
|
APN |
5 |
62,798,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01986:Arap2
|
APN |
5 |
62,779,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02032:Arap2
|
APN |
5 |
62,828,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02262:Arap2
|
APN |
5 |
62,800,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02331:Arap2
|
APN |
5 |
62,807,025 (GRCm39) |
splice site |
probably benign |
|
|
IGL02527:Arap2
|
APN |
5 |
62,906,650 (GRCm39) |
missense |
probably benign |
|
|
IGL02803:Arap2
|
APN |
5 |
62,906,452 (GRCm39) |
missense |
probably benign |
|
|
IGL02864:Arap2
|
APN |
5 |
62,835,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03078:Arap2
|
APN |
5 |
62,890,408 (GRCm39) |
splice site |
probably benign |
|
|
IGL03154:Arap2
|
APN |
5 |
62,800,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03213:Arap2
|
APN |
5 |
62,906,438 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Arap2
|
APN |
5 |
62,779,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03288:Arap2
|
APN |
5 |
62,761,959 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4354001:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0012:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Arap2
|
UTSW |
5 |
62,840,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0166:Arap2
|
UTSW |
5 |
62,833,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0472:Arap2
|
UTSW |
5 |
62,864,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0551:Arap2
|
UTSW |
5 |
62,798,666 (GRCm39) |
splice site |
probably null |
|
|
R0607:Arap2
|
UTSW |
5 |
62,763,474 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0617:Arap2
|
UTSW |
5 |
62,807,250 (GRCm39) |
splice site |
probably benign |
|
|
R0975:Arap2
|
UTSW |
5 |
62,888,229 (GRCm39) |
splice site |
probably benign |
|
|
R0976:Arap2
|
UTSW |
5 |
62,807,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1164:Arap2
|
UTSW |
5 |
62,840,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1268:Arap2
|
UTSW |
5 |
62,887,964 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1480:Arap2
|
UTSW |
5 |
62,826,472 (GRCm39) |
nonsense |
probably null |
|
|
R1502:Arap2
|
UTSW |
5 |
62,761,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1543:Arap2
|
UTSW |
5 |
62,763,498 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1962:Arap2
|
UTSW |
5 |
62,834,007 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2040:Arap2
|
UTSW |
5 |
62,906,259 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2118:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2131:Arap2
|
UTSW |
5 |
62,835,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2201:Arap2
|
UTSW |
5 |
62,864,028 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2215:Arap2
|
UTSW |
5 |
62,834,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3027:Arap2
|
UTSW |
5 |
62,827,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3053:Arap2
|
UTSW |
5 |
62,906,200 (GRCm39) |
missense |
probably benign |
0.35 |
|
R3975:Arap2
|
UTSW |
5 |
62,906,237 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4272:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4273:Arap2
|
UTSW |
5 |
62,828,322 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4326:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4327:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4328:Arap2
|
UTSW |
5 |
62,779,206 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4451:Arap2
|
UTSW |
5 |
62,906,513 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4659:Arap2
|
UTSW |
5 |
62,811,469 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4665:Arap2
|
UTSW |
5 |
62,827,312 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4715:Arap2
|
UTSW |
5 |
62,906,437 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4808:Arap2
|
UTSW |
5 |
62,887,984 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4941:Arap2
|
UTSW |
5 |
62,906,821 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4983:Arap2
|
UTSW |
5 |
62,833,868 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5095:Arap2
|
UTSW |
5 |
62,811,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5156:Arap2
|
UTSW |
5 |
62,826,524 (GRCm39) |
nonsense |
probably null |
|
|
R5201:Arap2
|
UTSW |
5 |
62,840,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Arap2
|
UTSW |
5 |
62,872,089 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5359:Arap2
|
UTSW |
5 |
62,840,762 (GRCm39) |
nonsense |
probably null |
|
|
R5426:Arap2
|
UTSW |
5 |
62,800,159 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5503:Arap2
|
UTSW |
5 |
62,787,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5605:Arap2
|
UTSW |
5 |
62,772,410 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R5764:Arap2
|
UTSW |
5 |
62,800,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Arap2
|
UTSW |
5 |
62,834,506 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5846:Arap2
|
UTSW |
5 |
62,807,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Arap2
|
UTSW |
5 |
62,828,297 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6173:Arap2
|
UTSW |
5 |
62,906,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Arap2
|
UTSW |
5 |
62,872,074 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6249:Arap2
|
UTSW |
5 |
62,803,536 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6386:Arap2
|
UTSW |
5 |
62,761,865 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6424:Arap2
|
UTSW |
5 |
62,840,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6744:Arap2
|
UTSW |
5 |
62,906,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6766:Arap2
|
UTSW |
5 |
62,834,443 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6990:Arap2
|
UTSW |
5 |
62,833,860 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7067:Arap2
|
UTSW |
5 |
62,811,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7098:Arap2
|
UTSW |
5 |
62,833,293 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7107:Arap2
|
UTSW |
5 |
62,763,551 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7156:Arap2
|
UTSW |
5 |
62,761,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7174:Arap2
|
UTSW |
5 |
62,761,621 (GRCm39) |
missense |
probably benign |
|
|
R7187:Arap2
|
UTSW |
5 |
62,826,396 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7197:Arap2
|
UTSW |
5 |
62,798,729 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7214:Arap2
|
UTSW |
5 |
62,906,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7317:Arap2
|
UTSW |
5 |
62,807,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7438:Arap2
|
UTSW |
5 |
62,906,818 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7452:Arap2
|
UTSW |
5 |
62,833,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7495:Arap2
|
UTSW |
5 |
62,833,893 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7796:Arap2
|
UTSW |
5 |
62,888,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7936:Arap2
|
UTSW |
5 |
62,888,048 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8116:Arap2
|
UTSW |
5 |
62,887,954 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Arap2
|
UTSW |
5 |
62,779,324 (GRCm39) |
splice site |
probably null |
|
|
R8277:Arap2
|
UTSW |
5 |
62,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Arap2
|
UTSW |
5 |
62,761,669 (GRCm39) |
nonsense |
probably null |
|
|
R8398:Arap2
|
UTSW |
5 |
62,906,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Arap2
|
UTSW |
5 |
62,888,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8973:Arap2
|
UTSW |
5 |
62,855,668 (GRCm39) |
nonsense |
probably null |
|
|
R9102:Arap2
|
UTSW |
5 |
62,906,341 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9121:Arap2
|
UTSW |
5 |
62,906,326 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9174:Arap2
|
UTSW |
5 |
62,855,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9222:Arap2
|
UTSW |
5 |
62,828,421 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9281:Arap2
|
UTSW |
5 |
62,906,848 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9399:Arap2
|
UTSW |
5 |
62,763,455 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9450:Arap2
|
UTSW |
5 |
62,855,762 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9467:Arap2
|
UTSW |
5 |
62,887,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9567:Arap2
|
UTSW |
5 |
62,761,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9577:Arap2
|
UTSW |
5 |
62,769,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9626:Arap2
|
UTSW |
5 |
62,906,878 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9688:Arap2
|
UTSW |
5 |
62,872,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACAGTCGCTATCATTAAAGAAGAGC -3'
(R):5'- AAGGTCATCATCCTGGCTCC -3'
Sequencing Primer
(F):5'- TCGCTATCATTAAAGAAGAGCAATTC -3'
(R):5'- TCCAGGGCATCTGCATAGG -3'
|
| Posted On |
2019-09-13 |
Incidental Mutation