Mutagenetix > Incidental Mutation

Incidental Mutation 'R8002:Dnah1'

616419

Institutional Source

Beutler Lab

Gene Symbol

Dnah1

Ensembl Gene

ENSMUSG00000019027

Gene Name

dynein, axonemal, heavy chain 1

Synonyms

MDHC7, B230373P09Rik, ferf1, G1-415-19, E030034C22Rik, Dnahc1

MMRRC Submission

046042-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R8002 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

30982332-31045853 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 31020679 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Histidine at position 1230 (L1230H)

Ref Sequence

ENSEMBL: ENSMUSP00000043281 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048603]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000048603
AA Change: L1230H

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000043281
Gene: ENSMUSG00000019027
AA Change: L1230H

Domain	Start	End	E-Value	Type
low complexity region	43	59	N/A	INTRINSIC
Pfam:DHC_N2	998	1404	6.3e-146	PFAM
AAA	1558	1697	6.02e-1	SMART
AAA	1839	2077	4.66e0	SMART
low complexity region	2149	2157	N/A	INTRINSIC
AAA	2204	2353	2.35e-1	SMART
Pfam:AAA_8	2533	2803	7.7e-84	PFAM
Pfam:MT	2815	3165	9.9e-57	PFAM
Pfam:AAA_9	3185	3410	1.1e-93	PFAM
Pfam:Dynein_heavy	3545	4246	2.7e-275	PFAM

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
PHENOTYPE: Homozygous mutants are male sterile, and show impaired ciliary and flagellar motility that is also observed in the tracheal cilia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acsm2	C	T	7: 119,172,480 (GRCm39)	R133C	possibly damaging	Het
Adgrf4	T	C	17: 42,978,683 (GRCm39)	E220G	probably benign	Het
Alx3	T	A	3: 107,508,055 (GRCm39)	L188*	probably null	Het
Arhgef2	A	T	3: 88,554,117 (GRCm39)	I969F	probably damaging	Het
Atf6	A	G	1: 170,646,823 (GRCm39)	V350A	probably benign	Het
Atp1a3	C	A	7: 24,700,096 (GRCm39)	G88V	probably damaging	Het
Brd8	T	C	18: 34,741,609 (GRCm39)	T360A	probably benign	Het
Casp1	C	A	9: 5,303,164 (GRCm39)	T206K	possibly damaging	Het
Ccdc150	A	G	1: 54,311,656 (GRCm39)	E214G	probably damaging	Het
Ccdc81	T	C	7: 89,525,343 (GRCm39)	E477G	probably benign	Het
Celsr2	G	T	3: 108,311,285 (GRCm39)	R1409S	probably damaging	Het
Chd6	T	C	2: 160,832,241 (GRCm39)	D977G	probably damaging	Het
Cpne3	A	T	4: 19,528,232 (GRCm39)	F342I	probably damaging	Het
Crot	A	C	5: 9,043,599 (GRCm39)	S8A	probably benign	Het
Cyp11b2	T	C	15: 74,727,881 (GRCm39)	H67R	probably damaging	Het
Dqx1	G	A	6: 83,035,558 (GRCm39)	D24N	probably damaging	Het
Gabrg3	T	C	7: 56,384,716 (GRCm39)	T282A	possibly damaging	Het
Gm13199	A	G	2: 5,867,458 (GRCm39)	S13P	unknown	Het
Gnptab	A	T	10: 88,276,130 (GRCm39)	D1139V	probably benign	Het
Hdac1-ps	T	C	17: 78,799,716 (GRCm39)	S236P	probably damaging	Het
Jtb	T	C	3: 90,141,251 (GRCm39)	S76P	probably benign	Het
Klk1b27	T	A	7: 43,705,445 (GRCm39)	D172E	probably benign	Het
Lpcat4	G	A	2: 112,074,699 (GRCm39)	V307I	probably benign	Het
Ltn1	A	C	16: 87,212,835 (GRCm39)	S575R	probably benign	Het
Map3k13	A	G	16: 21,723,878 (GRCm39)	T287A	probably benign	Het
Marco	T	G	1: 120,422,509 (GRCm39)	I58L	probably benign	Het
Nadk	G	T	4: 155,661,655 (GRCm39)		probably null	Het
Or11h7	A	T	14: 50,891,314 (GRCm39)	I207F	probably damaging	Het
Otof	G	A	5: 30,537,954 (GRCm39)	T1215I	probably benign	Het
Pigw	A	T	11: 84,769,249 (GRCm39)	C27S	probably benign	Het
Pla2g10	A	T	16: 13,542,912 (GRCm39)	M125K	unknown	Het
Rfx4	A	C	10: 84,676,721 (GRCm39)	M204L	probably damaging	Het
Septin1	T	C	7: 126,815,074 (GRCm39)	D209G	probably damaging	Het
Slc1a7	G	A	4: 107,869,473 (GRCm39)	V513M	probably benign	Het
Slc26a4	T	C	12: 31,597,969 (GRCm39)	D159G	probably benign	Het
Sptbn4	C	A	7: 27,117,417 (GRCm39)	S444I	possibly damaging	Het
Srebf2	C	T	15: 82,062,966 (GRCm39)	R468C	probably damaging	Het
Stard6	T	A	18: 70,633,597 (GRCm39)	D201E	possibly damaging	Het
Tas2r114	T	C	6: 131,666,102 (GRCm39)	T309A	probably damaging	Het
Tdrd6	C	A	17: 43,940,710 (GRCm39)	A113S	probably damaging	Het
Tigd2	T	G	6: 59,187,494 (GRCm39)	N120K	probably damaging	Het
Tomm70a	A	G	16: 56,957,097 (GRCm39)	N224S	probably damaging	Het
Tspo	T	C	15: 83,455,640 (GRCm39)	V9A	probably benign	Het
Vmn1r21	T	A	6: 57,821,199 (GRCm39)	I82L	probably benign	Het
Vmn2r103	T	A	17: 20,019,511 (GRCm39)	C532S	probably damaging	Het
Vmn2r76	T	C	7: 85,879,271 (GRCm39)	N343S	probably benign	Het
Wdr62	T	C	7: 29,951,785 (GRCm39)	K665E	probably damaging	Het
Xpc	T	A	6: 91,469,287 (GRCm39)	N820I	probably damaging	Het
Zfp418	A	G	7: 7,184,873 (GRCm39)	T279A	probably benign	Het

Other mutations in Dnah1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Dnah1	APN	14	31,009,830 (GRCm39)	missense	probably benign	0.01
IGL00227:Dnah1	APN	14	31,008,853 (GRCm39)	missense	probably damaging	1.00
IGL00491:Dnah1	APN	14	30,983,796 (GRCm39)	missense	probably damaging	1.00
IGL00787:Dnah1	APN	14	31,022,020 (GRCm39)	missense	possibly damaging	0.91
IGL00809:Dnah1	APN	14	31,022,766 (GRCm39)	nonsense	probably null
IGL00911:Dnah1	APN	14	31,026,391 (GRCm39)	splice site	probably null
IGL00949:Dnah1	APN	14	31,029,047 (GRCm39)	missense	probably benign	0.00
IGL00976:Dnah1	APN	14	31,000,095 (GRCm39)	missense	probably damaging	1.00
IGL01484:Dnah1	APN	14	31,021,897 (GRCm39)	missense	probably damaging	0.98
IGL01629:Dnah1	APN	14	31,014,277 (GRCm39)	missense	probably damaging	1.00
IGL01716:Dnah1	APN	14	30,985,335 (GRCm39)	missense	probably benign	0.34
IGL01893:Dnah1	APN	14	30,988,427 (GRCm39)	missense	probably damaging	1.00
IGL01933:Dnah1	APN	14	31,032,872 (GRCm39)	missense	probably benign	0.40
IGL01938:Dnah1	APN	14	31,005,844 (GRCm39)	missense	probably benign
IGL02032:Dnah1	APN	14	30,996,326 (GRCm39)	missense	probably benign
IGL02052:Dnah1	APN	14	30,990,743 (GRCm39)	missense	probably damaging	0.99
IGL02097:Dnah1	APN	14	31,026,958 (GRCm39)	missense	possibly damaging	0.92
IGL02127:Dnah1	APN	14	31,026,885 (GRCm39)	missense	probably benign	0.00
IGL02143:Dnah1	APN	14	31,005,246 (GRCm39)	missense	probably damaging	1.00
IGL02158:Dnah1	APN	14	31,022,924 (GRCm39)	missense	probably benign	0.00
IGL02442:Dnah1	APN	14	31,009,835 (GRCm39)	missense	probably damaging	1.00
IGL02525:Dnah1	APN	14	31,027,790 (GRCm39)	missense	probably benign	0.05
IGL02558:Dnah1	APN	14	30,996,336 (GRCm39)	missense	possibly damaging	0.96
IGL02633:Dnah1	APN	14	31,006,772 (GRCm39)	missense	probably benign	0.05
IGL02720:Dnah1	APN	14	30,984,177 (GRCm39)	missense	probably damaging	0.96
IGL02728:Dnah1	APN	14	31,005,955 (GRCm39)	missense	probably benign	0.44
IGL02738:Dnah1	APN	14	31,014,597 (GRCm39)	missense	probably benign	0.27
IGL02863:Dnah1	APN	14	31,017,250 (GRCm39)	missense	probably damaging	0.99
IGL02944:Dnah1	APN	14	31,022,828 (GRCm39)	missense	possibly damaging	0.88
IGL03110:Dnah1	APN	14	30,988,674 (GRCm39)	missense	probably benign	0.40
IGL03201:Dnah1	APN	14	31,022,906 (GRCm39)	missense	probably benign	0.13
IGL03215:Dnah1	APN	14	30,996,348 (GRCm39)	missense	probably damaging	1.00
IGL03230:Dnah1	APN	14	30,992,023 (GRCm39)	missense	probably damaging	1.00
IGL03248:Dnah1	APN	14	30,991,846 (GRCm39)	missense	probably damaging	1.00
IGL03267:Dnah1	APN	14	31,008,545 (GRCm39)	missense	probably benign	0.00
IGL03299:Dnah1	APN	14	31,037,079 (GRCm39)	nonsense	probably null
IGL03301:Dnah1	APN	14	31,014,649 (GRCm39)	missense	probably damaging	1.00
ergonomic	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
Faraday	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
K3955:Dnah1	UTSW	14	30,988,416 (GRCm39)	missense	probably benign
PIT1430001:Dnah1	UTSW	14	30,984,537 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Dnah1	UTSW	14	31,006,412 (GRCm39)	missense	probably damaging	1.00
R0043:Dnah1	UTSW	14	30,996,362 (GRCm39)	missense	probably damaging	0.97
R0092:Dnah1	UTSW	14	30,993,566 (GRCm39)	missense	probably benign	0.00
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0101:Dnah1	UTSW	14	31,005,856 (GRCm39)	missense	probably damaging	1.00
R0119:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0136:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0144:Dnah1	UTSW	14	30,989,831 (GRCm39)	splice site	probably benign
R0279:Dnah1	UTSW	14	31,024,332 (GRCm39)	missense	possibly damaging	0.94
R0299:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah1	UTSW	14	31,000,108 (GRCm39)	missense	probably benign	0.00
R0739:Dnah1	UTSW	14	30,987,872 (GRCm39)	nonsense	probably null
R0789:Dnah1	UTSW	14	31,026,548 (GRCm39)	missense	probably benign
R0826:Dnah1	UTSW	14	31,025,864 (GRCm39)	missense	probably benign	0.02
R1102:Dnah1	UTSW	14	31,018,414 (GRCm39)	nonsense	probably null
R1116:Dnah1	UTSW	14	31,029,824 (GRCm39)	missense	probably benign	0.13
R1229:Dnah1	UTSW	14	31,032,808 (GRCm39)	missense	probably benign	0.11
R1447:Dnah1	UTSW	14	31,028,855 (GRCm39)	missense	probably benign	0.06
R1449:Dnah1	UTSW	14	30,985,908 (GRCm39)	missense	probably damaging	1.00
R1462:Dnah1	UTSW	14	30,990,738 (GRCm39)	splice site	probably benign
R1482:Dnah1	UTSW	14	31,016,831 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah1	UTSW	14	31,038,715 (GRCm39)	missense	probably benign
R1512:Dnah1	UTSW	14	31,014,994 (GRCm39)	missense	probably damaging	1.00
R1591:Dnah1	UTSW	14	30,994,289 (GRCm39)	missense	probably benign	0.01
R1598:Dnah1	UTSW	14	31,023,219 (GRCm39)	missense	probably benign	0.07
R1644:Dnah1	UTSW	14	31,024,249 (GRCm39)	splice site	probably benign
R1672:Dnah1	UTSW	14	30,998,157 (GRCm39)	missense	probably damaging	1.00
R1713:Dnah1	UTSW	14	31,001,139 (GRCm39)	missense	probably damaging	1.00
R1769:Dnah1	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
R1796:Dnah1	UTSW	14	30,983,050 (GRCm39)	missense	probably benign	0.00
R1902:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1903:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1905:Dnah1	UTSW	14	30,986,587 (GRCm39)	missense	probably benign	0.06
R1908:Dnah1	UTSW	14	30,984,515 (GRCm39)	missense	probably damaging	1.00
R1972:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R1973:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R2004:Dnah1	UTSW	14	31,023,813 (GRCm39)	missense	possibly damaging	0.79
R2051:Dnah1	UTSW	14	31,001,080 (GRCm39)	missense	probably damaging	1.00
R2062:Dnah1	UTSW	14	30,993,086 (GRCm39)	missense	probably damaging	1.00
R2188:Dnah1	UTSW	14	31,001,121 (GRCm39)	missense	probably damaging	0.98
R2240:Dnah1	UTSW	14	31,021,931 (GRCm39)	missense	probably benign	0.00
R2862:Dnah1	UTSW	14	31,006,719 (GRCm39)	missense	probably benign	0.21
R2894:Dnah1	UTSW	14	31,020,718 (GRCm39)	missense	possibly damaging	0.67
R3120:Dnah1	UTSW	14	30,988,779 (GRCm39)	nonsense	probably null
R3410:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3411:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3435:Dnah1	UTSW	14	31,038,631 (GRCm39)	missense	probably damaging	0.96
R3615:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3616:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3741:Dnah1	UTSW	14	30,987,424 (GRCm39)	splice site	probably benign
R3805:Dnah1	UTSW	14	31,016,720 (GRCm39)	missense	possibly damaging	0.67
R3894:Dnah1	UTSW	14	31,028,985 (GRCm39)	missense	probably benign
R4007:Dnah1	UTSW	14	31,025,741 (GRCm39)	splice site	probably benign
R4201:Dnah1	UTSW	14	30,984,227 (GRCm39)	missense	probably benign	0.00
R4232:Dnah1	UTSW	14	31,026,873 (GRCm39)	missense	probably benign
R4372:Dnah1	UTSW	14	31,026,879 (GRCm39)	missense	probably damaging	1.00
R4391:Dnah1	UTSW	14	31,016,792 (GRCm39)	missense	probably damaging	1.00
R4423:Dnah1	UTSW	14	31,006,718 (GRCm39)	missense	probably benign	0.00
R4526:Dnah1	UTSW	14	31,007,955 (GRCm39)	missense	probably benign	0.05
R4650:Dnah1	UTSW	14	31,006,844 (GRCm39)	splice site	probably null
R4723:Dnah1	UTSW	14	30,994,899 (GRCm39)	missense	probably damaging	1.00
R4748:Dnah1	UTSW	14	31,041,902 (GRCm39)	missense	probably benign
R4783:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4784:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4785:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4843:Dnah1	UTSW	14	30,986,920 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah1	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
R4897:Dnah1	UTSW	14	30,989,496 (GRCm39)	missense	probably damaging	1.00
R4911:Dnah1	UTSW	14	31,017,280 (GRCm39)	missense	probably damaging	1.00
R4985:Dnah1	UTSW	14	31,008,855 (GRCm39)	missense	probably null	1.00
R5070:Dnah1	UTSW	14	31,004,375 (GRCm39)	missense	probably benign	0.05
R5128:Dnah1	UTSW	14	31,018,152 (GRCm39)	splice site	probably null
R5409:Dnah1	UTSW	14	30,985,212 (GRCm39)	missense	probably damaging	1.00
R5436:Dnah1	UTSW	14	31,038,704 (GRCm39)	missense	probably benign
R5481:Dnah1	UTSW	14	31,030,828 (GRCm39)	missense	possibly damaging	0.55
R5550:Dnah1	UTSW	14	31,038,665 (GRCm39)	missense	probably benign	0.00
R5555:Dnah1	UTSW	14	31,012,776 (GRCm39)	missense	probably damaging	0.99
R5566:Dnah1	UTSW	14	30,996,323 (GRCm39)	missense	probably benign	0.35
R5623:Dnah1	UTSW	14	31,007,980 (GRCm39)	missense	possibly damaging	0.62
R5701:Dnah1	UTSW	14	30,996,001 (GRCm39)	missense	probably damaging	1.00
R5751:Dnah1	UTSW	14	31,032,863 (GRCm39)	missense	probably benign	0.00
R5823:Dnah1	UTSW	14	30,988,375 (GRCm39)	missense	possibly damaging	0.92
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6090:Dnah1	UTSW	14	30,991,382 (GRCm39)	missense	possibly damaging	0.83
R6139:Dnah1	UTSW	14	31,007,984 (GRCm39)	missense	probably benign	0.02
R6145:Dnah1	UTSW	14	31,022,927 (GRCm39)	missense	probably benign	0.07
R6306:Dnah1	UTSW	14	31,026,544 (GRCm39)	missense	probably damaging	0.97
R6376:Dnah1	UTSW	14	30,997,565 (GRCm39)	missense	probably damaging	1.00
R6451:Dnah1	UTSW	14	31,022,765 (GRCm39)	missense	probably benign	0.08
R6549:Dnah1	UTSW	14	30,991,340 (GRCm39)	missense	probably damaging	1.00
R6748:Dnah1	UTSW	14	31,021,945 (GRCm39)	missense	probably damaging	0.99
R6826:Dnah1	UTSW	14	31,008,247 (GRCm39)	missense	probably benign	0.00
R6870:Dnah1	UTSW	14	30,993,018 (GRCm39)	nonsense	probably null
R6932:Dnah1	UTSW	14	31,009,733 (GRCm39)	missense	probably damaging	1.00
R6944:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R7033:Dnah1	UTSW	14	30,986,882 (GRCm39)	missense	probably damaging	1.00
R7078:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R7133:Dnah1	UTSW	14	31,008,033 (GRCm39)	missense	probably benign
R7136:Dnah1	UTSW	14	31,020,613 (GRCm39)	missense	probably damaging	1.00
R7203:Dnah1	UTSW	14	30,996,339 (GRCm39)	missense	probably benign
R7241:Dnah1	UTSW	14	30,986,896 (GRCm39)	missense	probably benign	0.00
R7260:Dnah1	UTSW	14	30,991,343 (GRCm39)	missense	probably damaging	1.00
R7264:Dnah1	UTSW	14	30,991,851 (GRCm39)	missense	probably benign
R7291:Dnah1	UTSW	14	31,020,662 (GRCm39)	missense	probably damaging	1.00
R7293:Dnah1	UTSW	14	31,009,820 (GRCm39)	missense	probably damaging	1.00
R7300:Dnah1	UTSW	14	30,991,798 (GRCm39)	missense	probably benign	0.05
R7319:Dnah1	UTSW	14	31,018,551 (GRCm39)	missense	probably benign	0.02
R7323:Dnah1	UTSW	14	31,020,664 (GRCm39)	missense	probably damaging	1.00
R7472:Dnah1	UTSW	14	31,022,748 (GRCm39)	missense	possibly damaging	0.80
R7472:Dnah1	UTSW	14	30,983,547 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah1	UTSW	14	31,037,079 (GRCm39)	nonsense	probably null
R7526:Dnah1	UTSW	14	31,009,833 (GRCm39)	missense	possibly damaging	0.49
R7560:Dnah1	UTSW	14	31,026,940 (GRCm39)	missense	probably benign
R7574:Dnah1	UTSW	14	31,041,865 (GRCm39)	missense	probably benign	0.00
R7617:Dnah1	UTSW	14	31,006,739 (GRCm39)	missense	possibly damaging	0.80
R7620:Dnah1	UTSW	14	31,025,863 (GRCm39)	missense	possibly damaging	0.47
R7692:Dnah1	UTSW	14	31,014,295 (GRCm39)	missense	probably benign	0.00
R7702:Dnah1	UTSW	14	31,032,866 (GRCm39)	missense	probably benign
R7786:Dnah1	UTSW	14	30,984,478 (GRCm39)	missense	probably damaging	1.00
R7984:Dnah1	UTSW	14	30,989,772 (GRCm39)	missense	probably damaging	1.00
R8022:Dnah1	UTSW	14	30,986,971 (GRCm39)	missense	probably damaging	1.00
R8032:Dnah1	UTSW	14	30,993,505 (GRCm39)	missense	probably damaging	1.00
R8099:Dnah1	UTSW	14	31,024,321 (GRCm39)	missense	probably benign	0.00
R8171:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R8263:Dnah1	UTSW	14	31,015,134 (GRCm39)	missense	probably damaging	1.00
R8274:Dnah1	UTSW	14	31,017,531 (GRCm39)	missense	probably benign	0.00
R8345:Dnah1	UTSW	14	30,986,551 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8353:Dnah1	UTSW	14	31,005,159 (GRCm39)	missense	probably benign
R8356:Dnah1	UTSW	14	30,994,972 (GRCm39)	missense	probably benign	0.00
R8376:Dnah1	UTSW	14	31,023,303 (GRCm39)	missense	probably damaging	1.00
R8448:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8461:Dnah1	UTSW	14	31,027,915 (GRCm39)	missense	probably benign	0.00
R8534:Dnah1	UTSW	14	31,023,805 (GRCm39)	missense	probably benign	0.16
R8544:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R8679:Dnah1	UTSW	14	30,989,767 (GRCm39)	missense	possibly damaging	0.77
R8716:Dnah1	UTSW	14	30,989,941 (GRCm39)	critical splice donor site	probably benign
R8750:Dnah1	UTSW	14	31,026,924 (GRCm39)	missense	probably benign	0.30
R8790:Dnah1	UTSW	14	31,018,232 (GRCm39)	missense	possibly damaging	0.89
R8808:Dnah1	UTSW	14	31,008,771 (GRCm39)	missense	probably benign
R8821:Dnah1	UTSW	14	31,018,455 (GRCm39)	missense	probably benign
R8887:Dnah1	UTSW	14	31,032,997 (GRCm39)	missense	probably damaging	1.00
R8948:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8950:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8955:Dnah1	UTSW	14	31,007,950 (GRCm39)	missense	probably benign
R8987:Dnah1	UTSW	14	31,033,704 (GRCm39)	missense	possibly damaging	0.93
R8998:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R8999:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R9015:Dnah1	UTSW	14	30,986,316 (GRCm39)	missense	probably damaging	0.96
R9031:Dnah1	UTSW	14	31,001,128 (GRCm39)	missense	probably benign
R9088:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably benign	0.04
R9096:Dnah1	UTSW	14	30,983,027 (GRCm39)	missense	probably damaging	0.99
R9117:Dnah1	UTSW	14	31,033,581 (GRCm39)	splice site	probably benign
R9157:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9296:Dnah1	UTSW	14	30,996,011 (GRCm39)	critical splice acceptor site	probably null
R9313:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9325:Dnah1	UTSW	14	30,998,160 (GRCm39)	missense	possibly damaging	0.69
R9352:Dnah1	UTSW	14	31,038,620 (GRCm39)	missense	probably benign	0.00
R9411:Dnah1	UTSW	14	31,018,256 (GRCm39)	missense	probably damaging	1.00
R9429:Dnah1	UTSW	14	30,997,499 (GRCm39)	nonsense	probably null
R9452:Dnah1	UTSW	14	31,018,448 (GRCm39)	missense	probably benign	0.35
R9562:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9565:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9616:Dnah1	UTSW	14	31,026,400 (GRCm39)	missense	probably null	0.20
R9621:Dnah1	UTSW	14	31,016,772 (GRCm39)	missense	probably damaging	1.00
R9677:Dnah1	UTSW	14	31,029,821 (GRCm39)	missense	probably benign	0.00
R9723:Dnah1	UTSW	14	30,987,946 (GRCm39)	missense	probably damaging	1.00
R9758:Dnah1	UTSW	14	30,985,395 (GRCm39)	missense	probably damaging	0.98
RF006:Dnah1	UTSW	14	31,029,832 (GRCm39)	missense	probably benign	0.08
Z1088:Dnah1	UTSW	14	31,026,768 (GRCm39)	missense	probably benign	0.17

Predicted Primers

PCR Primer
(F):5'- CAATGTGATCAGGACCTTGGG -3'
(R):5'- AAGCCCCAAGTGCAGAATTG -3'

Sequencing Primer
(F):5'- GGAGGTCCTAGCTGTCTTCC -3'
(R):5'- GTAGCGCTACCTAGTAGATGC -3'

Posted On

2020-01-23