Mutagenetix > Incidental Mutation

Incidental Mutation 'R7526:Dnah1'

583020

Institutional Source

Beutler Lab

Gene Symbol

Dnah1

Ensembl Gene

ENSMUSG00000019027

Gene Name

dynein, axonemal, heavy chain 1

Synonyms

MDHC7, B230373P09Rik, ferf1, G1-415-19, E030034C22Rik, Dnahc1

MMRRC Submission

045598-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R7526 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

30982332-31045853 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 31009833 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Isoleucine at position 1912 (F1912I)

Ref Sequence

ENSEMBL: ENSMUSP00000043281 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048603]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000048603
AA Change: F1912I

PolyPhen 2 Score 0.485 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000043281
Gene: ENSMUSG00000019027
AA Change: F1912I

Domain	Start	End	E-Value	Type
low complexity region	43	59	N/A	INTRINSIC
Pfam:DHC_N2	998	1404	6.3e-146	PFAM
AAA	1558	1697	6.02e-1	SMART
AAA	1839	2077	4.66e0	SMART
low complexity region	2149	2157	N/A	INTRINSIC
AAA	2204	2353	2.35e-1	SMART
Pfam:AAA_8	2533	2803	7.7e-84	PFAM
Pfam:MT	2815	3165	9.9e-57	PFAM
Pfam:AAA_9	3185	3410	1.1e-93	PFAM
Pfam:Dynein_heavy	3545	4246	2.7e-275	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

100% (74/74)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
PHENOTYPE: Homozygous mutants are male sterile, and show impaired ciliary and flagellar motility that is also observed in the tracheal cilia. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 76 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700086D15Rik	A	T	11: 65,043,807 (GRCm39)	F85I	unknown	Het
Ankrd22	A	T	19: 34,126,765 (GRCm39)	W22R	possibly damaging	Het
Aqr	A	T	2: 113,938,590 (GRCm39)	H1287Q	probably damaging	Het
Armh1	C	A	4: 117,070,938 (GRCm39)	A396S	probably benign	Het
Atp8b5	A	G	4: 43,366,609 (GRCm39)	E791G	probably damaging	Het
Bicd1	T	G	6: 149,415,224 (GRCm39)	S646A	possibly damaging	Het
Bmpr1b	A	T	3: 141,562,360 (GRCm39)	Y276N	probably damaging	Het
Cadps2	T	C	6: 23,496,850 (GRCm39)	H465R	probably damaging	Het
Card11	A	T	5: 140,899,184 (GRCm39)		probably null	Het
Ccdc9	A	G	7: 16,016,325 (GRCm39)	L139P	probably damaging	Het
Cdk5rap3	A	T	11: 96,800,771 (GRCm39)	M355K	probably benign	Het
Cnot2	A	T	10: 116,342,985 (GRCm39)	V116E	probably benign	Het
Defb48	A	G	14: 63,215,280 (GRCm39)	V32A	possibly damaging	Het
Dmkn	A	G	7: 30,477,076 (GRCm39)	D460G	possibly damaging	Het
Dmxl2	A	G	9: 54,308,241 (GRCm39)	V2170A	possibly damaging	Het
Dok3	C	T	13: 55,675,306 (GRCm39)	V71I	probably benign	Het
Dzip3	A	T	16: 48,795,837 (GRCm39)	F178Y	probably damaging	Het
Enpp1	T	C	10: 24,550,308 (GRCm39)		probably null	Het
Eogt	A	G	6: 97,090,913 (GRCm39)	F409L	probably damaging	Het
Erich6	A	T	3: 58,538,110 (GRCm39)	L218H	probably damaging	Het
Fam186a	G	C	15: 99,839,796 (GRCm39)	I2149M	possibly damaging	Het
Fat1	G	A	8: 45,476,464 (GRCm39)	V1837I	probably damaging	Het
Flrt3	T	A	2: 140,502,126 (GRCm39)	T501S	probably damaging	Het
Fmn1	A	C	2: 113,518,479 (GRCm39)	E1365D	probably damaging	Het
Fzd5	G	T	1: 64,775,251 (GRCm39)	P170Q	probably benign	Het
Gm14326	G	A	2: 177,588,298 (GRCm39)	H233Y	probably damaging	Het
Gm19410	G	A	8: 36,257,766 (GRCm39)	V735M	probably damaging	Het
Gm21886	ACTCACTGAGGCCTGCAGACAGTAGGTGCTCACTGAGGCCTGCAGACAGTAGGTGCTCACTGAGGCCTGCAGACAGTAGGTGCTCACTGAGACCTGCAGACAGTAGGTGCTCACTGAGACCTGCAGACAGTAGGTGCTCACTGAGG	ACTCACTGAGGCCTGCAGACAGTAGGTGCTCACTGAGGCCTGCAGACAGTAGGTGCTCACTGAGACCTGCAGACAGTAGGTGCTCACTGAGACCTGCAGACAGTAGGTGCTCACTGAGG	18: 80,133,040 (GRCm39)		probably benign	Het
Gm2832	A	T	14: 41,002,919 (GRCm39)	I143L		Het
Greb1	G	A	12: 16,766,766 (GRCm39)	T344I	probably benign	Het
Grik2	A	T	10: 49,399,918 (GRCm39)	Y271N	possibly damaging	Het
Grin3b	A	G	10: 79,808,885 (GRCm39)	N212D	probably benign	Het
Hgsnat	A	G	8: 26,461,077 (GRCm39)	L187P	probably damaging	Het
Hmcn1	A	G	1: 150,532,324 (GRCm39)	I3152T	probably damaging	Het
Hsp90aa1	A	T	12: 110,661,728 (GRCm39)	I96N	unknown	Het
Il18r1	T	A	1: 40,510,932 (GRCm39)	L6I	probably damaging	Het
Ing3	G	A	6: 21,953,798 (GRCm39)	V80I	probably damaging	Het
Kif18b	T	C	11: 102,805,493 (GRCm39)	I255V	probably damaging	Het
Kif2c	A	T	4: 117,039,629 (GRCm39)	N20K	possibly damaging	Het
Mfsd6l	T	C	11: 68,448,864 (GRCm39)	W572R	probably damaging	Het
Mybphl	A	G	3: 108,281,496 (GRCm39)	T71A	probably benign	Het
Myo7a	G	T	7: 97,734,655 (GRCm39)	T613K	possibly damaging	Het
Nfatc3	T	C	8: 106,805,715 (GRCm39)	S195P	probably damaging	Het
Nrg1	T	C	8: 32,308,351 (GRCm39)	N603S	probably benign	Het
Or52ae9	T	C	7: 103,389,607 (GRCm39)	Y280C	probably damaging	Het
Or8k22	A	T	2: 86,163,697 (GRCm39)	M1K	probably null	Het
Or8k37	A	G	2: 86,470,013 (GRCm39)	I13T	possibly damaging	Het
Parp8	T	C	13: 117,031,341 (GRCm39)	E457G	probably damaging	Het
Pclo	T	C	5: 14,571,076 (GRCm39)	F154L	probably benign	Het
Pear1	A	G	3: 87,659,875 (GRCm39)	S704P	probably damaging	Het
Pkib	A	G	10: 57,612,394 (GRCm39)	T92A	probably benign	Het
Pnpla7	A	G	2: 24,888,678 (GRCm39)	R376G	possibly damaging	Het
Pramel28	A	T	4: 143,692,387 (GRCm39)	C205S	probably benign	Het
Ptprd	T	A	4: 75,984,564 (GRCm39)	E527D	probably benign	Het
Pum1	T	C	4: 130,474,337 (GRCm39)	V469A	probably damaging	Het
Rnf148	G	A	6: 23,654,283 (GRCm39)	Q238*	probably null	Het
Scn9a	A	C	2: 66,313,990 (GRCm39)	N1909K	probably benign	Het
Sema3c	A	T	5: 17,932,594 (GRCm39)	H699L	possibly damaging	Het
Sema3f	A	T	9: 107,566,927 (GRCm39)	C201S	probably damaging	Het
Serinc2	T	A	4: 130,152,583 (GRCm39)	D206V	probably benign	Het
Serping1	A	T	2: 84,597,637 (GRCm39)	S415T	probably benign	Het
Sirpb1b	A	T	3: 15,613,932 (GRCm39)	L50Q	probably damaging	Het
Slc25a22	T	C	7: 141,011,296 (GRCm39)	E262G	probably benign	Het
Slc5a8	A	G	10: 88,738,353 (GRCm39)	I205M	probably damaging	Het
Sod2	G	T	17: 13,226,918 (GRCm39)		probably benign	Het
Tec	T	C	5: 72,943,362 (GRCm39)	I118V	probably benign	Het
Tenm3	A	T	8: 48,740,847 (GRCm39)	V1212E	probably damaging	Het
Tex44	G	A	1: 86,354,237 (GRCm39)	V49I	probably benign	Het
Tmem132d	A	T	5: 127,861,205 (GRCm39)	L972*	probably null	Het
Tpte	G	A	8: 22,815,563 (GRCm39)		probably null	Het
Trim6	T	A	7: 103,882,039 (GRCm39)	I456N	probably damaging	Het
Ubr4	G	C	4: 139,149,728 (GRCm39)	V520L	probably benign	Het
Ubxn8	A	T	8: 34,123,635 (GRCm39)	N101K	probably benign	Het
Vmn2r60	AG	A	7: 41,845,158 (GRCm39)		probably null	Het
Vmn2r83	A	G	10: 79,327,392 (GRCm39)	T667A	probably damaging	Het
Zpld2	T	C	4: 133,927,384 (GRCm39)		probably null	Het

Other mutations in Dnah1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Dnah1	APN	14	31,009,830 (GRCm39)	missense	probably benign	0.01
IGL00227:Dnah1	APN	14	31,008,853 (GRCm39)	missense	probably damaging	1.00
IGL00491:Dnah1	APN	14	30,983,796 (GRCm39)	missense	probably damaging	1.00
IGL00787:Dnah1	APN	14	31,022,020 (GRCm39)	missense	possibly damaging	0.91
IGL00809:Dnah1	APN	14	31,022,766 (GRCm39)	nonsense	probably null
IGL00911:Dnah1	APN	14	31,026,391 (GRCm39)	splice site	probably null
IGL00949:Dnah1	APN	14	31,029,047 (GRCm39)	missense	probably benign	0.00
IGL00976:Dnah1	APN	14	31,000,095 (GRCm39)	missense	probably damaging	1.00
IGL01484:Dnah1	APN	14	31,021,897 (GRCm39)	missense	probably damaging	0.98
IGL01629:Dnah1	APN	14	31,014,277 (GRCm39)	missense	probably damaging	1.00
IGL01716:Dnah1	APN	14	30,985,335 (GRCm39)	missense	probably benign	0.34
IGL01893:Dnah1	APN	14	30,988,427 (GRCm39)	missense	probably damaging	1.00
IGL01933:Dnah1	APN	14	31,032,872 (GRCm39)	missense	probably benign	0.40
IGL01938:Dnah1	APN	14	31,005,844 (GRCm39)	missense	probably benign
IGL02032:Dnah1	APN	14	30,996,326 (GRCm39)	missense	probably benign
IGL02052:Dnah1	APN	14	30,990,743 (GRCm39)	missense	probably damaging	0.99
IGL02097:Dnah1	APN	14	31,026,958 (GRCm39)	missense	possibly damaging	0.92
IGL02127:Dnah1	APN	14	31,026,885 (GRCm39)	missense	probably benign	0.00
IGL02143:Dnah1	APN	14	31,005,246 (GRCm39)	missense	probably damaging	1.00
IGL02158:Dnah1	APN	14	31,022,924 (GRCm39)	missense	probably benign	0.00
IGL02442:Dnah1	APN	14	31,009,835 (GRCm39)	missense	probably damaging	1.00
IGL02525:Dnah1	APN	14	31,027,790 (GRCm39)	missense	probably benign	0.05
IGL02558:Dnah1	APN	14	30,996,336 (GRCm39)	missense	possibly damaging	0.96
IGL02633:Dnah1	APN	14	31,006,772 (GRCm39)	missense	probably benign	0.05
IGL02720:Dnah1	APN	14	30,984,177 (GRCm39)	missense	probably damaging	0.96
IGL02728:Dnah1	APN	14	31,005,955 (GRCm39)	missense	probably benign	0.44
IGL02738:Dnah1	APN	14	31,014,597 (GRCm39)	missense	probably benign	0.27
IGL02863:Dnah1	APN	14	31,017,250 (GRCm39)	missense	probably damaging	0.99
IGL02944:Dnah1	APN	14	31,022,828 (GRCm39)	missense	possibly damaging	0.88
IGL03110:Dnah1	APN	14	30,988,674 (GRCm39)	missense	probably benign	0.40
IGL03201:Dnah1	APN	14	31,022,906 (GRCm39)	missense	probably benign	0.13
IGL03215:Dnah1	APN	14	30,996,348 (GRCm39)	missense	probably damaging	1.00
IGL03230:Dnah1	APN	14	30,992,023 (GRCm39)	missense	probably damaging	1.00
IGL03248:Dnah1	APN	14	30,991,846 (GRCm39)	missense	probably damaging	1.00
IGL03267:Dnah1	APN	14	31,008,545 (GRCm39)	missense	probably benign	0.00
IGL03299:Dnah1	APN	14	31,037,079 (GRCm39)	nonsense	probably null
IGL03301:Dnah1	APN	14	31,014,649 (GRCm39)	missense	probably damaging	1.00
ergonomic	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
Faraday	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
K3955:Dnah1	UTSW	14	30,988,416 (GRCm39)	missense	probably benign
PIT1430001:Dnah1	UTSW	14	30,984,537 (GRCm39)	missense	probably damaging	1.00
PIT4382001:Dnah1	UTSW	14	31,006,412 (GRCm39)	missense	probably damaging	1.00
R0043:Dnah1	UTSW	14	30,996,362 (GRCm39)	missense	probably damaging	0.97
R0092:Dnah1	UTSW	14	30,993,566 (GRCm39)	missense	probably benign	0.00
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0100:Dnah1	UTSW	14	30,984,109 (GRCm39)	critical splice donor site	probably null
R0101:Dnah1	UTSW	14	31,005,856 (GRCm39)	missense	probably damaging	1.00
R0119:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0136:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0144:Dnah1	UTSW	14	30,989,831 (GRCm39)	splice site	probably benign
R0279:Dnah1	UTSW	14	31,024,332 (GRCm39)	missense	possibly damaging	0.94
R0299:Dnah1	UTSW	14	30,998,115 (GRCm39)	missense	probably damaging	1.00
R0316:Dnah1	UTSW	14	31,000,108 (GRCm39)	missense	probably benign	0.00
R0739:Dnah1	UTSW	14	30,987,872 (GRCm39)	nonsense	probably null
R0789:Dnah1	UTSW	14	31,026,548 (GRCm39)	missense	probably benign
R0826:Dnah1	UTSW	14	31,025,864 (GRCm39)	missense	probably benign	0.02
R1102:Dnah1	UTSW	14	31,018,414 (GRCm39)	nonsense	probably null
R1116:Dnah1	UTSW	14	31,029,824 (GRCm39)	missense	probably benign	0.13
R1229:Dnah1	UTSW	14	31,032,808 (GRCm39)	missense	probably benign	0.11
R1447:Dnah1	UTSW	14	31,028,855 (GRCm39)	missense	probably benign	0.06
R1449:Dnah1	UTSW	14	30,985,908 (GRCm39)	missense	probably damaging	1.00
R1462:Dnah1	UTSW	14	30,990,738 (GRCm39)	splice site	probably benign
R1482:Dnah1	UTSW	14	31,016,831 (GRCm39)	missense	probably damaging	1.00
R1500:Dnah1	UTSW	14	31,038,715 (GRCm39)	missense	probably benign
R1512:Dnah1	UTSW	14	31,014,994 (GRCm39)	missense	probably damaging	1.00
R1591:Dnah1	UTSW	14	30,994,289 (GRCm39)	missense	probably benign	0.01
R1598:Dnah1	UTSW	14	31,023,219 (GRCm39)	missense	probably benign	0.07
R1644:Dnah1	UTSW	14	31,024,249 (GRCm39)	splice site	probably benign
R1672:Dnah1	UTSW	14	30,998,157 (GRCm39)	missense	probably damaging	1.00
R1713:Dnah1	UTSW	14	31,001,139 (GRCm39)	missense	probably damaging	1.00
R1769:Dnah1	UTSW	14	31,032,839 (GRCm39)	missense	probably null	0.05
R1796:Dnah1	UTSW	14	30,983,050 (GRCm39)	missense	probably benign	0.00
R1902:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1903:Dnah1	UTSW	14	31,041,716 (GRCm39)	missense	probably damaging	0.99
R1905:Dnah1	UTSW	14	30,986,587 (GRCm39)	missense	probably benign	0.06
R1908:Dnah1	UTSW	14	30,984,515 (GRCm39)	missense	probably damaging	1.00
R1972:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R1973:Dnah1	UTSW	14	30,987,348 (GRCm39)	nonsense	probably null
R2004:Dnah1	UTSW	14	31,023,813 (GRCm39)	missense	possibly damaging	0.79
R2051:Dnah1	UTSW	14	31,001,080 (GRCm39)	missense	probably damaging	1.00
R2062:Dnah1	UTSW	14	30,993,086 (GRCm39)	missense	probably damaging	1.00
R2188:Dnah1	UTSW	14	31,001,121 (GRCm39)	missense	probably damaging	0.98
R2240:Dnah1	UTSW	14	31,021,931 (GRCm39)	missense	probably benign	0.00
R2862:Dnah1	UTSW	14	31,006,719 (GRCm39)	missense	probably benign	0.21
R2894:Dnah1	UTSW	14	31,020,718 (GRCm39)	missense	possibly damaging	0.67
R3120:Dnah1	UTSW	14	30,988,779 (GRCm39)	nonsense	probably null
R3410:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3411:Dnah1	UTSW	14	30,991,774 (GRCm39)	missense	possibly damaging	0.55
R3435:Dnah1	UTSW	14	31,038,631 (GRCm39)	missense	probably damaging	0.96
R3615:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3616:Dnah1	UTSW	14	31,037,105 (GRCm39)	missense	possibly damaging	0.92
R3741:Dnah1	UTSW	14	30,987,424 (GRCm39)	splice site	probably benign
R3805:Dnah1	UTSW	14	31,016,720 (GRCm39)	missense	possibly damaging	0.67
R3894:Dnah1	UTSW	14	31,028,985 (GRCm39)	missense	probably benign
R4007:Dnah1	UTSW	14	31,025,741 (GRCm39)	splice site	probably benign
R4201:Dnah1	UTSW	14	30,984,227 (GRCm39)	missense	probably benign	0.00
R4232:Dnah1	UTSW	14	31,026,873 (GRCm39)	missense	probably benign
R4372:Dnah1	UTSW	14	31,026,879 (GRCm39)	missense	probably damaging	1.00
R4391:Dnah1	UTSW	14	31,016,792 (GRCm39)	missense	probably damaging	1.00
R4423:Dnah1	UTSW	14	31,006,718 (GRCm39)	missense	probably benign	0.00
R4526:Dnah1	UTSW	14	31,007,955 (GRCm39)	missense	probably benign	0.05
R4650:Dnah1	UTSW	14	31,006,844 (GRCm39)	splice site	probably null
R4723:Dnah1	UTSW	14	30,994,899 (GRCm39)	missense	probably damaging	1.00
R4748:Dnah1	UTSW	14	31,041,902 (GRCm39)	missense	probably benign
R4783:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4784:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4785:Dnah1	UTSW	14	30,985,436 (GRCm39)	missense	probably damaging	1.00
R4843:Dnah1	UTSW	14	30,986,920 (GRCm39)	missense	probably damaging	1.00
R4879:Dnah1	UTSW	14	31,022,705 (GRCm39)	missense	possibly damaging	0.91
R4897:Dnah1	UTSW	14	30,989,496 (GRCm39)	missense	probably damaging	1.00
R4911:Dnah1	UTSW	14	31,017,280 (GRCm39)	missense	probably damaging	1.00
R4985:Dnah1	UTSW	14	31,008,855 (GRCm39)	missense	probably null	1.00
R5070:Dnah1	UTSW	14	31,004,375 (GRCm39)	missense	probably benign	0.05
R5128:Dnah1	UTSW	14	31,018,152 (GRCm39)	splice site	probably null
R5409:Dnah1	UTSW	14	30,985,212 (GRCm39)	missense	probably damaging	1.00
R5436:Dnah1	UTSW	14	31,038,704 (GRCm39)	missense	probably benign
R5481:Dnah1	UTSW	14	31,030,828 (GRCm39)	missense	possibly damaging	0.55
R5550:Dnah1	UTSW	14	31,038,665 (GRCm39)	missense	probably benign	0.00
R5555:Dnah1	UTSW	14	31,012,776 (GRCm39)	missense	probably damaging	0.99
R5566:Dnah1	UTSW	14	30,996,323 (GRCm39)	missense	probably benign	0.35
R5623:Dnah1	UTSW	14	31,007,980 (GRCm39)	missense	possibly damaging	0.62
R5701:Dnah1	UTSW	14	30,996,001 (GRCm39)	missense	probably damaging	1.00
R5751:Dnah1	UTSW	14	31,032,863 (GRCm39)	missense	probably benign	0.00
R5823:Dnah1	UTSW	14	30,988,375 (GRCm39)	missense	possibly damaging	0.92
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6030:Dnah1	UTSW	14	30,989,984 (GRCm39)	missense	probably damaging	1.00
R6090:Dnah1	UTSW	14	30,991,382 (GRCm39)	missense	possibly damaging	0.83
R6139:Dnah1	UTSW	14	31,007,984 (GRCm39)	missense	probably benign	0.02
R6145:Dnah1	UTSW	14	31,022,927 (GRCm39)	missense	probably benign	0.07
R6306:Dnah1	UTSW	14	31,026,544 (GRCm39)	missense	probably damaging	0.97
R6376:Dnah1	UTSW	14	30,997,565 (GRCm39)	missense	probably damaging	1.00
R6451:Dnah1	UTSW	14	31,022,765 (GRCm39)	missense	probably benign	0.08
R6549:Dnah1	UTSW	14	30,991,340 (GRCm39)	missense	probably damaging	1.00
R6748:Dnah1	UTSW	14	31,021,945 (GRCm39)	missense	probably damaging	0.99
R6826:Dnah1	UTSW	14	31,008,247 (GRCm39)	missense	probably benign	0.00
R6870:Dnah1	UTSW	14	30,993,018 (GRCm39)	nonsense	probably null
R6932:Dnah1	UTSW	14	31,009,733 (GRCm39)	missense	probably damaging	1.00
R6944:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R7033:Dnah1	UTSW	14	30,986,882 (GRCm39)	missense	probably damaging	1.00
R7078:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R7133:Dnah1	UTSW	14	31,008,033 (GRCm39)	missense	probably benign
R7136:Dnah1	UTSW	14	31,020,613 (GRCm39)	missense	probably damaging	1.00
R7203:Dnah1	UTSW	14	30,996,339 (GRCm39)	missense	probably benign
R7241:Dnah1	UTSW	14	30,986,896 (GRCm39)	missense	probably benign	0.00
R7260:Dnah1	UTSW	14	30,991,343 (GRCm39)	missense	probably damaging	1.00
R7264:Dnah1	UTSW	14	30,991,851 (GRCm39)	missense	probably benign
R7291:Dnah1	UTSW	14	31,020,662 (GRCm39)	missense	probably damaging	1.00
R7293:Dnah1	UTSW	14	31,009,820 (GRCm39)	missense	probably damaging	1.00
R7300:Dnah1	UTSW	14	30,991,798 (GRCm39)	missense	probably benign	0.05
R7319:Dnah1	UTSW	14	31,018,551 (GRCm39)	missense	probably benign	0.02
R7323:Dnah1	UTSW	14	31,020,664 (GRCm39)	missense	probably damaging	1.00
R7472:Dnah1	UTSW	14	31,022,748 (GRCm39)	missense	possibly damaging	0.80
R7472:Dnah1	UTSW	14	30,983,547 (GRCm39)	missense	probably damaging	1.00
R7499:Dnah1	UTSW	14	31,037,079 (GRCm39)	nonsense	probably null
R7560:Dnah1	UTSW	14	31,026,940 (GRCm39)	missense	probably benign
R7574:Dnah1	UTSW	14	31,041,865 (GRCm39)	missense	probably benign	0.00
R7617:Dnah1	UTSW	14	31,006,739 (GRCm39)	missense	possibly damaging	0.80
R7620:Dnah1	UTSW	14	31,025,863 (GRCm39)	missense	possibly damaging	0.47
R7692:Dnah1	UTSW	14	31,014,295 (GRCm39)	missense	probably benign	0.00
R7702:Dnah1	UTSW	14	31,032,866 (GRCm39)	missense	probably benign
R7786:Dnah1	UTSW	14	30,984,478 (GRCm39)	missense	probably damaging	1.00
R7984:Dnah1	UTSW	14	30,989,772 (GRCm39)	missense	probably damaging	1.00
R8002:Dnah1	UTSW	14	31,020,679 (GRCm39)	missense	probably damaging	1.00
R8022:Dnah1	UTSW	14	30,986,971 (GRCm39)	missense	probably damaging	1.00
R8032:Dnah1	UTSW	14	30,993,505 (GRCm39)	missense	probably damaging	1.00
R8099:Dnah1	UTSW	14	31,024,321 (GRCm39)	missense	probably benign	0.00
R8171:Dnah1	UTSW	14	31,019,067 (GRCm39)	missense	probably damaging	1.00
R8263:Dnah1	UTSW	14	31,015,134 (GRCm39)	missense	probably damaging	1.00
R8274:Dnah1	UTSW	14	31,017,531 (GRCm39)	missense	probably benign	0.00
R8345:Dnah1	UTSW	14	30,986,551 (GRCm39)	missense	probably damaging	1.00
R8348:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8353:Dnah1	UTSW	14	31,005,159 (GRCm39)	missense	probably benign
R8356:Dnah1	UTSW	14	30,994,972 (GRCm39)	missense	probably benign	0.00
R8376:Dnah1	UTSW	14	31,023,303 (GRCm39)	missense	probably damaging	1.00
R8448:Dnah1	UTSW	14	31,015,682 (GRCm39)	missense	probably damaging	1.00
R8461:Dnah1	UTSW	14	31,027,915 (GRCm39)	missense	probably benign	0.00
R8534:Dnah1	UTSW	14	31,023,805 (GRCm39)	missense	probably benign	0.16
R8544:Dnah1	UTSW	14	30,990,861 (GRCm39)	missense	probably damaging	1.00
R8679:Dnah1	UTSW	14	30,989,767 (GRCm39)	missense	possibly damaging	0.77
R8716:Dnah1	UTSW	14	30,989,941 (GRCm39)	critical splice donor site	probably benign
R8750:Dnah1	UTSW	14	31,026,924 (GRCm39)	missense	probably benign	0.30
R8790:Dnah1	UTSW	14	31,018,232 (GRCm39)	missense	possibly damaging	0.89
R8808:Dnah1	UTSW	14	31,008,771 (GRCm39)	missense	probably benign
R8821:Dnah1	UTSW	14	31,018,455 (GRCm39)	missense	probably benign
R8887:Dnah1	UTSW	14	31,032,997 (GRCm39)	missense	probably damaging	1.00
R8948:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8950:Dnah1	UTSW	14	31,012,396 (GRCm39)	missense	probably damaging	1.00
R8955:Dnah1	UTSW	14	31,007,950 (GRCm39)	missense	probably benign
R8987:Dnah1	UTSW	14	31,033,704 (GRCm39)	missense	possibly damaging	0.93
R8998:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R8999:Dnah1	UTSW	14	31,018,235 (GRCm39)	missense	probably benign	0.12
R9015:Dnah1	UTSW	14	30,986,316 (GRCm39)	missense	probably damaging	0.96
R9031:Dnah1	UTSW	14	31,001,128 (GRCm39)	missense	probably benign
R9088:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably benign	0.04
R9096:Dnah1	UTSW	14	30,983,027 (GRCm39)	missense	probably damaging	0.99
R9117:Dnah1	UTSW	14	31,033,581 (GRCm39)	splice site	probably benign
R9157:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9296:Dnah1	UTSW	14	30,996,011 (GRCm39)	critical splice acceptor site	probably null
R9313:Dnah1	UTSW	14	30,987,970 (GRCm39)	missense	probably damaging	0.97
R9325:Dnah1	UTSW	14	30,998,160 (GRCm39)	missense	possibly damaging	0.69
R9352:Dnah1	UTSW	14	31,038,620 (GRCm39)	missense	probably benign	0.00
R9411:Dnah1	UTSW	14	31,018,256 (GRCm39)	missense	probably damaging	1.00
R9429:Dnah1	UTSW	14	30,997,499 (GRCm39)	nonsense	probably null
R9452:Dnah1	UTSW	14	31,018,448 (GRCm39)	missense	probably benign	0.35
R9562:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9565:Dnah1	UTSW	14	30,986,394 (GRCm39)	missense	probably damaging	1.00
R9616:Dnah1	UTSW	14	31,026,400 (GRCm39)	missense	probably null	0.20
R9621:Dnah1	UTSW	14	31,016,772 (GRCm39)	missense	probably damaging	1.00
R9677:Dnah1	UTSW	14	31,029,821 (GRCm39)	missense	probably benign	0.00
R9723:Dnah1	UTSW	14	30,987,946 (GRCm39)	missense	probably damaging	1.00
R9758:Dnah1	UTSW	14	30,985,395 (GRCm39)	missense	probably damaging	0.98
RF006:Dnah1	UTSW	14	31,029,832 (GRCm39)	missense	probably benign	0.08
Z1088:Dnah1	UTSW	14	31,026,768 (GRCm39)	missense	probably benign	0.17

Predicted Primers

PCR Primer
(F):5'- TAGGACGTGGCTCCAAGAAG -3'
(R):5'- GACCAATACTTCTGTATCTGTTTGG -3'

Sequencing Primer
(F):5'- ATGGCGCAGACTCCAGAG -3'
(R):5'- CTGTTTGGTAACCACTCAAAAACTG -3'

Posted On

2019-10-17