Incidental Mutation 'R1950:Insrr'
| ID |
217180 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Insrr
|
| Ensembl Gene |
ENSMUSG00000005640 |
| Gene Name |
insulin receptor-related receptor |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.274)
|
| Stock # |
R1950 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
87704258-87723408 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 87721820 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 1198
(N1198S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103208
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029711]
[ENSMUST00000029714]
[ENSMUST00000090981]
[ENSMUST00000107582]
|
| AlphaFold |
Q9WTL4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029711
AA Change: N1198S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000029711
Gene: ENSMUSG00000005640
AA Change: N1198S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
1.8e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
3.8e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029714
|
| SMART Domains |
Protein: ENSMUSP00000029714
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000090981
|
| SMART Domains |
Protein: ENSMUSP00000088503
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107582
AA Change: N1198S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000103208
Gene: ENSMUSG00000005640
AA Change: N1198S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
7.7e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
1.6e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no anomalies in pancreatic islet morphology, beta-cell mass or pancreatic secretory function. This mutation in combination with Insr mutant mice does not affect the diabetes predisposition of Insr mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akap9 |
A |
G |
5: 4,010,677 (GRCm39) |
N478S |
probably damaging |
Het |
| Als2 |
T |
A |
1: 59,224,760 (GRCm39) |
|
probably null |
Het |
| Ankfy1 |
A |
G |
11: 72,651,155 (GRCm39) |
Y1035C |
probably damaging |
Het |
| Ankrd11 |
T |
C |
8: 123,616,608 (GRCm39) |
T2394A |
probably damaging |
Het |
| Axin1 |
G |
C |
17: 26,412,938 (GRCm39) |
G780R |
possibly damaging |
Het |
| Carm1 |
A |
T |
9: 21,485,812 (GRCm39) |
T127S |
probably benign |
Het |
| Ccdc73 |
T |
C |
2: 104,757,280 (GRCm39) |
I81T |
probably benign |
Het |
| Cdh12 |
T |
C |
15: 21,237,965 (GRCm39) |
Y67H |
probably damaging |
Het |
| Cfap65 |
C |
A |
1: 74,946,819 (GRCm39) |
G1297V |
probably damaging |
Het |
| Cfap74 |
T |
C |
4: 155,511,887 (GRCm39) |
|
probably null |
Het |
| Chit1 |
A |
G |
1: 134,078,968 (GRCm39) |
Y426C |
probably damaging |
Het |
| Clpp |
A |
G |
17: 57,303,039 (GRCm39) |
|
probably benign |
Het |
| Clrn3 |
T |
G |
7: 135,115,813 (GRCm39) |
Y179S |
possibly damaging |
Het |
| Cntn5 |
A |
C |
9: 9,781,774 (GRCm39) |
M635R |
probably damaging |
Het |
| Col12a1 |
A |
T |
9: 79,537,831 (GRCm39) |
S2546T |
possibly damaging |
Het |
| Ctla2b |
T |
C |
13: 61,043,863 (GRCm39) |
N102S |
possibly damaging |
Het |
| Cwf19l2 |
A |
T |
9: 3,418,674 (GRCm39) |
I154F |
probably benign |
Het |
| Dffa |
C |
A |
4: 149,188,839 (GRCm39) |
S44R |
probably benign |
Het |
| Ehbp1 |
T |
A |
11: 22,009,228 (GRCm39) |
K930M |
probably damaging |
Het |
| Erc2 |
T |
A |
14: 27,634,857 (GRCm39) |
S473T |
probably damaging |
Het |
| Fbxw24 |
A |
T |
9: 109,434,481 (GRCm39) |
L373H |
probably benign |
Het |
| Fer1l4 |
T |
C |
2: 155,890,194 (GRCm39) |
I244V |
probably damaging |
Het |
| Fgfr2 |
G |
A |
7: 129,800,211 (GRCm39) |
T245M |
probably damaging |
Het |
| Garin1b |
C |
T |
6: 29,335,815 (GRCm39) |
|
probably null |
Het |
| Gbp9 |
T |
A |
5: 105,229,112 (GRCm39) |
M512L |
probably benign |
Het |
| Glg1 |
T |
A |
8: 111,892,271 (GRCm39) |
K251I |
possibly damaging |
Het |
| Gm10553 |
A |
G |
1: 85,078,141 (GRCm39) |
D86G |
possibly damaging |
Het |
| Gm5622 |
T |
C |
14: 51,893,229 (GRCm39) |
V52A |
probably benign |
Het |
| Gucy1b1 |
A |
G |
3: 81,952,716 (GRCm39) |
V239A |
probably benign |
Het |
| Gzma |
A |
G |
13: 113,230,463 (GRCm39) |
L246P |
probably damaging |
Het |
| Hibadh |
C |
A |
6: 52,533,448 (GRCm39) |
A223S |
probably benign |
Het |
| Hydin |
C |
A |
8: 111,336,619 (GRCm39) |
T5132N |
possibly damaging |
Het |
| Ivl |
T |
C |
3: 92,479,420 (GRCm39) |
E215G |
possibly damaging |
Het |
| Jmjd1c |
A |
G |
10: 67,075,701 (GRCm39) |
D2037G |
possibly damaging |
Het |
| Kcna3 |
G |
A |
3: 106,944,988 (GRCm39) |
C417Y |
probably damaging |
Het |
| Klra2 |
T |
C |
6: 131,207,078 (GRCm39) |
N177S |
probably benign |
Het |
| Llgl2 |
T |
C |
11: 115,741,892 (GRCm39) |
S645P |
probably damaging |
Het |
| Lrrc15 |
T |
C |
16: 30,092,649 (GRCm39) |
E230G |
probably benign |
Het |
| Magel2 |
C |
A |
7: 62,028,163 (GRCm39) |
Q356K |
possibly damaging |
Het |
| Mcm6 |
A |
G |
1: 128,273,726 (GRCm39) |
V368A |
probably benign |
Het |
| Myh8 |
G |
A |
11: 67,169,830 (GRCm39) |
V50M |
possibly damaging |
Het |
| Myrf |
A |
T |
19: 10,195,554 (GRCm39) |
F419I |
possibly damaging |
Het |
| Nrbp1 |
T |
A |
5: 31,403,157 (GRCm39) |
I210N |
probably damaging |
Het |
| Or10ak16 |
G |
A |
4: 118,750,537 (GRCm39) |
V86M |
probably benign |
Het |
| Or52i2 |
A |
G |
7: 102,319,684 (GRCm39) |
M186V |
probably benign |
Het |
| Otud4 |
G |
A |
8: 80,372,961 (GRCm39) |
R93H |
probably damaging |
Het |
| Pank4 |
T |
A |
4: 155,056,977 (GRCm39) |
M390K |
probably benign |
Het |
| Pecam1 |
A |
G |
11: 106,576,029 (GRCm39) |
V401A |
probably damaging |
Het |
| Prdm6 |
C |
A |
18: 53,669,796 (GRCm39) |
T138K |
possibly damaging |
Het |
| Prl2c2 |
G |
C |
13: 13,176,786 (GRCm39) |
T47R |
probably damaging |
Het |
| Prpf8 |
A |
G |
11: 75,387,337 (GRCm39) |
E1206G |
possibly damaging |
Het |
| Prr30 |
A |
T |
14: 101,435,377 (GRCm39) |
I395N |
probably benign |
Het |
| Rab27a |
G |
A |
9: 72,982,751 (GRCm39) |
G19R |
probably damaging |
Het |
| Ramacl |
A |
G |
13: 67,055,269 (GRCm39) |
|
probably benign |
Het |
| Rrp12 |
A |
G |
19: 41,881,029 (GRCm39) |
V134A |
probably damaging |
Het |
| Scly |
A |
G |
1: 91,233,116 (GRCm39) |
T76A |
probably benign |
Het |
| Scube3 |
T |
C |
17: 28,383,274 (GRCm39) |
S439P |
possibly damaging |
Het |
| Shf |
G |
A |
2: 122,199,163 (GRCm39) |
P51S |
probably damaging |
Het |
| Sipa1l1 |
T |
C |
12: 82,388,233 (GRCm39) |
F153S |
probably damaging |
Het |
| Slc25a30 |
T |
G |
14: 76,007,007 (GRCm39) |
K163T |
possibly damaging |
Het |
| Slc26a8 |
T |
A |
17: 28,863,614 (GRCm39) |
D715V |
probably benign |
Het |
| Smr2 |
AT |
ATT |
5: 88,256,683 (GRCm39) |
|
probably null |
Het |
| Smr2 |
C |
CT |
5: 88,256,685 (GRCm39) |
|
probably null |
Het |
| Sp6 |
T |
G |
11: 96,912,940 (GRCm39) |
S218A |
probably benign |
Het |
| Spata21 |
T |
C |
4: 140,838,716 (GRCm39) |
V589A |
probably damaging |
Het |
| Sycp2 |
T |
C |
2: 178,044,593 (GRCm39) |
I71V |
probably benign |
Het |
| Syne2 |
G |
T |
12: 75,999,644 (GRCm39) |
G2347C |
probably benign |
Het |
| Tenm2 |
C |
T |
11: 35,954,004 (GRCm39) |
G1236R |
possibly damaging |
Het |
| Thbs4 |
A |
T |
13: 92,906,079 (GRCm39) |
N387K |
probably damaging |
Het |
| Tmem184a |
T |
C |
5: 139,793,381 (GRCm39) |
D216G |
probably damaging |
Het |
| Tprg1 |
T |
A |
16: 25,136,098 (GRCm39) |
S30T |
possibly damaging |
Het |
| Trip12 |
A |
T |
1: 84,738,522 (GRCm39) |
W778R |
probably damaging |
Het |
| Ttpa |
T |
C |
4: 20,008,633 (GRCm39) |
L65P |
probably damaging |
Het |
| Ush2a |
A |
T |
1: 188,487,382 (GRCm39) |
N3050I |
probably damaging |
Het |
| Xpot |
T |
C |
10: 121,455,053 (GRCm39) |
I30V |
probably benign |
Het |
| Zfp944 |
A |
G |
17: 22,558,681 (GRCm39) |
S189P |
probably benign |
Het |
| Zftraf1 |
A |
G |
15: 76,543,417 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Insrr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00718:Insrr
|
APN |
3 |
87,720,981 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00801:Insrr
|
APN |
3 |
87,721,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Insrr
|
APN |
3 |
87,708,099 (GRCm39) |
nonsense |
probably null |
|
|
IGL01755:Insrr
|
APN |
3 |
87,721,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02100:Insrr
|
APN |
3 |
87,718,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02261:Insrr
|
APN |
3 |
87,708,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Insrr
|
APN |
3 |
87,717,216 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02387:Insrr
|
APN |
3 |
87,720,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02478:Insrr
|
APN |
3 |
87,716,719 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02550:Insrr
|
APN |
3 |
87,711,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02555:Insrr
|
APN |
3 |
87,721,124 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02673:Insrr
|
APN |
3 |
87,720,368 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02724:Insrr
|
APN |
3 |
87,716,879 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02798:Insrr
|
APN |
3 |
87,717,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02969:Insrr
|
APN |
3 |
87,721,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL03073:Insrr
|
APN |
3 |
87,717,245 (GRCm39) |
splice site |
probably benign |
|
|
IGL03178:Insrr
|
APN |
3 |
87,709,848 (GRCm39) |
splice site |
probably null |
|
|
IGL03389:Insrr
|
APN |
3 |
87,716,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Insrr
|
APN |
3 |
87,716,638 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL02799:Insrr
|
UTSW |
3 |
87,720,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Insrr
|
UTSW |
3 |
87,716,923 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0357:Insrr
|
UTSW |
3 |
87,715,953 (GRCm39) |
splice site |
probably null |
|
|
R0501:Insrr
|
UTSW |
3 |
87,717,991 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0504:Insrr
|
UTSW |
3 |
87,720,463 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0522:Insrr
|
UTSW |
3 |
87,708,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Insrr
|
UTSW |
3 |
87,721,744 (GRCm39) |
splice site |
probably benign |
|
|
R0558:Insrr
|
UTSW |
3 |
87,718,288 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0599:Insrr
|
UTSW |
3 |
87,720,440 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1312:Insrr
|
UTSW |
3 |
87,707,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Insrr
|
UTSW |
3 |
87,711,369 (GRCm39) |
missense |
probably benign |
|
|
R1785:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1786:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1892:Insrr
|
UTSW |
3 |
87,721,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2080:Insrr
|
UTSW |
3 |
87,721,598 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2094:Insrr
|
UTSW |
3 |
87,710,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2130:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2131:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2133:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2220:Insrr
|
UTSW |
3 |
87,716,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2259:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2404:Insrr
|
UTSW |
3 |
87,709,974 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4027:Insrr
|
UTSW |
3 |
87,716,906 (GRCm39) |
missense |
probably benign |
|
|
R4042:Insrr
|
UTSW |
3 |
87,721,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4511:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4571:Insrr
|
UTSW |
3 |
87,708,194 (GRCm39) |
missense |
probably benign |
|
|
R4870:Insrr
|
UTSW |
3 |
87,718,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Insrr
|
UTSW |
3 |
87,722,572 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5393:Insrr
|
UTSW |
3 |
87,718,007 (GRCm39) |
splice site |
probably null |
|
|
R5685:Insrr
|
UTSW |
3 |
87,707,803 (GRCm39) |
splice site |
probably null |
|
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6047:Insrr
|
UTSW |
3 |
87,711,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6276:Insrr
|
UTSW |
3 |
87,707,826 (GRCm39) |
nonsense |
probably null |
|
|
R6298:Insrr
|
UTSW |
3 |
87,720,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6726:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6727:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6728:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6796:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7041:Insrr
|
UTSW |
3 |
87,722,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7169:Insrr
|
UTSW |
3 |
87,715,901 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7270:Insrr
|
UTSW |
3 |
87,710,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Insrr
|
UTSW |
3 |
87,721,623 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7398:Insrr
|
UTSW |
3 |
87,716,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7473:Insrr
|
UTSW |
3 |
87,711,838 (GRCm39) |
splice site |
probably null |
|
|
R7815:Insrr
|
UTSW |
3 |
87,716,002 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8159:Insrr
|
UTSW |
3 |
87,707,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8289:Insrr
|
UTSW |
3 |
87,721,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8309:Insrr
|
UTSW |
3 |
87,717,749 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8312:Insrr
|
UTSW |
3 |
87,707,791 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8445:Insrr
|
UTSW |
3 |
87,720,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8917:Insrr
|
UTSW |
3 |
87,718,276 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8960:Insrr
|
UTSW |
3 |
87,720,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8989:Insrr
|
UTSW |
3 |
87,722,664 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9015:Insrr
|
UTSW |
3 |
87,720,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:Insrr
|
UTSW |
3 |
87,720,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9251:Insrr
|
UTSW |
3 |
87,717,391 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9327:Insrr
|
UTSW |
3 |
87,721,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9646:Insrr
|
UTSW |
3 |
87,721,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF022:Insrr
|
UTSW |
3 |
87,711,792 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1177:Insrr
|
UTSW |
3 |
87,708,134 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
Z1192:Insrr
|
UTSW |
3 |
87,709,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCACTCACTCAGATGTCTGG -3'
(R):5'- CGCTTTGGAGGAAGAAGGTC -3'
Sequencing Primer
(F):5'- CACTCACTCAGATGTCTGGTAGGG -3'
(R):5'- CCAAGGGTAGTGAGCACAGTG -3'
|
| Posted On |
2014-08-01 |
Incidental Mutation