Incidental Mutation 'R4609:Tanc2'
| ID |
344535 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tanc2
|
| Ensembl Gene |
ENSMUSG00000053580 |
| Gene Name |
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| Synonyms |
5730590C14Rik, 3526402J09Rik |
| MMRRC Submission |
041820-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4609 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
105480812-105820130 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 105801066 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 1094
(N1094S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097904
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100330]
|
| AlphaFold |
A2A690 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000089485
AA Change: N138S
|
| SMART Domains |
Protein: ENSMUSP00000086912
Gene: ENSMUSG00000053580
AA Change: N138S
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
35 |
63 |
1.16e3 |
SMART |
|
ANK
|
78 |
107 |
3.31e-1 |
SMART |
|
ANK
|
111 |
140 |
7.71e-2 |
SMART |
|
ANK
|
144 |
173 |
6.12e-5 |
SMART |
|
ANK
|
177 |
206 |
8.99e-3 |
SMART |
|
ANK
|
210 |
239 |
5.71e-5 |
SMART |
|
ANK
|
243 |
272 |
2.11e2 |
SMART |
|
Blast:TPR
|
289 |
322 |
3e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100330
AA Change: N1094S
PolyPhen 2
Score 0.236 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000097904
Gene: ENSMUSG00000053580
AA Change: N1094S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
32 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
129 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
362 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
436 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
823 |
834 |
N/A |
INTRINSIC |
|
ANK
|
846 |
878 |
2.08e3 |
SMART |
|
ANK
|
882 |
913 |
2.97e2 |
SMART |
|
ANK
|
917 |
946 |
5.75e-1 |
SMART |
|
ANK
|
950 |
979 |
8.62e1 |
SMART |
|
ANK
|
990 |
1018 |
1.16e3 |
SMART |
|
ANK
|
1033 |
1062 |
3.31e-1 |
SMART |
|
ANK
|
1066 |
1095 |
7.71e-2 |
SMART |
|
ANK
|
1099 |
1128 |
6.12e-5 |
SMART |
|
ANK
|
1132 |
1161 |
8.99e-3 |
SMART |
|
ANK
|
1165 |
1194 |
5.71e-5 |
SMART |
|
ANK
|
1198 |
1227 |
2.11e2 |
SMART |
|
TPR
|
1244 |
1277 |
3.89e1 |
SMART |
|
TPR
|
1291 |
1324 |
3.61e-2 |
SMART |
|
TPR
|
1325 |
1358 |
2.82e-4 |
SMART |
|
low complexity region
|
1369 |
1406 |
N/A |
INTRINSIC |
|
low complexity region
|
1533 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1787 |
1802 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000146162
AA Change: N226S
|
| SMART Domains |
Protein: ENSMUSP00000123674
Gene: ENSMUSG00000053580
AA Change: N226S
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
15 |
46 |
2.97e2 |
SMART |
|
ANK
|
50 |
79 |
5.75e-1 |
SMART |
|
ANK
|
83 |
112 |
8.62e1 |
SMART |
|
ANK
|
123 |
151 |
1.16e3 |
SMART |
|
ANK
|
166 |
195 |
3.31e-1 |
SMART |
|
ANK
|
199 |
228 |
7.71e-2 |
SMART |
|
ANK
|
232 |
261 |
6.12e-5 |
SMART |
|
ANK
|
265 |
294 |
8.99e-3 |
SMART |
|
ANK
|
298 |
327 |
5.71e-5 |
SMART |
|
ANK
|
331 |
360 |
3.44e1 |
SMART |
|
TPR
|
387 |
420 |
3.89e1 |
SMART |
|
TPR
|
434 |
467 |
3.61e-2 |
SMART |
|
TPR
|
468 |
501 |
2.82e-4 |
SMART |
|
low complexity region
|
512 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
682 |
N/A |
INTRINSIC |
|
low complexity region
|
930 |
945 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147975
|
| Meta Mutation Damage Score |
0.1831 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 94.9%
|
| Validation Efficiency |
99% (78/79) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap vector die prior to E12. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 7530416G11Rik |
T |
C |
15: 85,378,370 (GRCm39) |
D91G |
unknown |
Het |
| Adam10 |
T |
C |
9: 70,647,425 (GRCm39) |
Y42H |
probably damaging |
Het |
| Baiap3 |
A |
T |
17: 25,469,235 (GRCm39) |
C183S |
probably damaging |
Het |
| Bbs10 |
A |
G |
10: 111,136,995 (GRCm39) |
K703E |
probably benign |
Het |
| Bmp1 |
C |
T |
14: 70,715,406 (GRCm39) |
V910M |
probably benign |
Het |
| Brdt |
G |
A |
5: 107,507,802 (GRCm39) |
A677T |
probably benign |
Het |
| Cadps2 |
A |
T |
6: 23,587,578 (GRCm39) |
M304K |
probably damaging |
Het |
| Car9 |
A |
T |
4: 43,507,267 (GRCm39) |
D71V |
possibly damaging |
Het |
| Chml |
A |
T |
1: 175,514,723 (GRCm39) |
Y399* |
probably null |
Het |
| Cilk1 |
T |
A |
9: 78,075,071 (GRCm39) |
|
probably benign |
Het |
| Clasp1 |
A |
G |
1: 118,430,765 (GRCm39) |
|
probably benign |
Het |
| Cntnap5b |
G |
A |
1: 99,700,572 (GRCm39) |
|
probably null |
Het |
| Cpvl |
A |
T |
6: 53,951,605 (GRCm39) |
|
probably null |
Het |
| Crocc2 |
G |
A |
1: 93,096,516 (GRCm39) |
V24M |
possibly damaging |
Het |
| Cxcl16 |
T |
C |
11: 70,346,255 (GRCm39) |
Y226C |
probably damaging |
Het |
| Dio3 |
G |
T |
12: 110,246,444 (GRCm39) |
R260L |
probably damaging |
Het |
| Dmxl2 |
A |
G |
9: 54,353,796 (GRCm39) |
L724P |
probably damaging |
Het |
| Dnah7a |
A |
C |
1: 53,495,816 (GRCm39) |
F3214V |
possibly damaging |
Het |
| Dpy19l4 |
A |
T |
4: 11,295,999 (GRCm39) |
Y223* |
probably null |
Het |
| Dpysl4 |
T |
C |
7: 138,678,537 (GRCm39) |
V499A |
probably damaging |
Het |
| Ets2 |
A |
T |
16: 95,512,818 (GRCm39) |
K101N |
probably benign |
Het |
| Fbn2 |
A |
T |
18: 58,323,341 (GRCm39) |
Y200* |
probably null |
Het |
| Fem1c |
A |
T |
18: 46,639,015 (GRCm39) |
I329N |
probably damaging |
Het |
| Fhip1b |
A |
G |
7: 105,037,431 (GRCm39) |
I384T |
probably damaging |
Het |
| Gm8919 |
T |
C |
3: 11,724,530 (GRCm39) |
|
noncoding transcript |
Het |
| H2-Q5 |
A |
T |
17: 35,616,056 (GRCm39) |
H206L |
probably benign |
Het |
| Hexa |
T |
C |
9: 59,464,602 (GRCm39) |
F164S |
probably benign |
Het |
| Hk1 |
G |
T |
10: 62,194,194 (GRCm39) |
|
probably benign |
Het |
| Itih4 |
G |
A |
14: 30,623,626 (GRCm39) |
G915R |
probably damaging |
Het |
| Kcnq5 |
A |
T |
1: 21,475,292 (GRCm39) |
|
probably null |
Het |
| Krtap10-4 |
A |
T |
10: 77,662,630 (GRCm39) |
|
probably benign |
Het |
| Maml3 |
G |
T |
3: 51,763,013 (GRCm39) |
H650Q |
probably damaging |
Het |
| Mief1 |
C |
A |
15: 80,132,454 (GRCm39) |
P112Q |
probably benign |
Het |
| Morc3 |
A |
G |
16: 93,661,856 (GRCm39) |
E472G |
probably benign |
Het |
| Nap1l1 |
T |
A |
10: 111,328,741 (GRCm39) |
Y223* |
probably null |
Het |
| Nfix |
A |
T |
8: 85,453,119 (GRCm39) |
W312R |
probably damaging |
Het |
| Nfkbie |
A |
T |
17: 45,869,510 (GRCm39) |
N155I |
probably damaging |
Het |
| Nlgn2 |
A |
T |
11: 69,724,912 (GRCm39) |
M118K |
probably damaging |
Het |
| Nlrp5 |
A |
T |
7: 23,117,173 (GRCm39) |
Y299F |
probably benign |
Het |
| Nnt |
T |
C |
13: 119,494,072 (GRCm39) |
I556V |
possibly damaging |
Het |
| Oasl2 |
A |
T |
5: 115,037,857 (GRCm39) |
I85F |
possibly damaging |
Het |
| Ogg1 |
A |
C |
6: 113,305,393 (GRCm39) |
T69P |
probably damaging |
Het |
| Olfml2a |
G |
T |
2: 38,847,733 (GRCm39) |
V431L |
probably damaging |
Het |
| Or4d5 |
T |
C |
9: 40,012,102 (GRCm39) |
H228R |
possibly damaging |
Het |
| Or5p79 |
A |
T |
7: 108,221,711 (GRCm39) |
M231L |
probably benign |
Het |
| Palb2 |
G |
T |
7: 121,723,946 (GRCm39) |
A601E |
probably benign |
Het |
| Pcdhb20 |
G |
A |
18: 37,638,849 (GRCm39) |
M458I |
probably benign |
Het |
| Pde11a |
T |
C |
2: 76,121,585 (GRCm39) |
D332G |
possibly damaging |
Het |
| Pkd1l1 |
C |
T |
11: 8,908,964 (GRCm39) |
E347K |
unknown |
Het |
| Pou2af1 |
G |
A |
9: 51,149,525 (GRCm39) |
V206I |
possibly damaging |
Het |
| Prr16 |
A |
G |
18: 51,251,139 (GRCm39) |
D46G |
possibly damaging |
Het |
| Pus1 |
A |
G |
5: 110,928,184 (GRCm39) |
M1T |
probably null |
Het |
| Pygm |
T |
A |
19: 6,441,439 (GRCm39) |
V566D |
possibly damaging |
Het |
| Rb1 |
T |
A |
14: 73,499,954 (GRCm39) |
|
probably benign |
Het |
| Rhoj |
A |
T |
12: 75,446,980 (GRCm39) |
K200* |
probably null |
Het |
| Rnf213 |
A |
G |
11: 119,328,521 (GRCm39) |
I1985V |
possibly damaging |
Het |
| Septin11 |
G |
T |
5: 93,310,113 (GRCm39) |
M305I |
possibly damaging |
Het |
| Setdb2 |
T |
C |
14: 59,653,153 (GRCm39) |
Y383C |
probably damaging |
Het |
| Sfpq |
G |
C |
4: 126,915,404 (GRCm39) |
Q65H |
unknown |
Het |
| Skic8 |
A |
G |
9: 54,635,463 (GRCm39) |
V46A |
probably benign |
Het |
| Stard3nl |
G |
T |
13: 19,554,434 (GRCm39) |
A180E |
probably damaging |
Het |
| Trf |
C |
T |
9: 103,089,184 (GRCm39) |
A554T |
possibly damaging |
Het |
| Trmt13 |
T |
C |
3: 116,388,476 (GRCm39) |
|
probably benign |
Het |
| Tubb3 |
A |
G |
8: 124,147,658 (GRCm39) |
D197G |
probably damaging |
Het |
| Ube2e3 |
A |
G |
2: 78,749,056 (GRCm39) |
H135R |
probably damaging |
Het |
| Ugt1a10 |
A |
T |
1: 87,983,204 (GRCm39) |
M1L |
possibly damaging |
Het |
| Vmn1r233 |
A |
T |
17: 21,214,677 (GRCm39) |
I91N |
possibly damaging |
Het |
| Vmn2r88 |
A |
T |
14: 51,655,531 (GRCm39) |
D580V |
probably damaging |
Het |
| Vps33b |
A |
G |
7: 79,940,866 (GRCm39) |
Y593C |
probably benign |
Het |
| Wdr19 |
A |
G |
5: 65,385,885 (GRCm39) |
T622A |
possibly damaging |
Het |
| Wdr3 |
C |
T |
3: 100,047,516 (GRCm39) |
R853Q |
probably damaging |
Het |
| Xirp1 |
T |
C |
9: 119,845,572 (GRCm39) |
T1104A |
probably benign |
Het |
| Yipf1 |
G |
A |
4: 107,201,880 (GRCm39) |
|
probably null |
Het |
| Zbtb17 |
A |
G |
4: 141,193,809 (GRCm39) |
D651G |
probably damaging |
Het |
| Zbtb42 |
C |
T |
12: 112,646,976 (GRCm39) |
R384W |
probably damaging |
Het |
| Zbtb43 |
A |
T |
2: 33,344,055 (GRCm39) |
M390K |
probably benign |
Het |
| Zfp462 |
C |
T |
4: 55,011,889 (GRCm39) |
T1285M |
probably damaging |
Het |
|
| Other mutations in Tanc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00501:Tanc2
|
APN |
11 |
105,814,046 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00688:Tanc2
|
APN |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00709:Tanc2
|
APN |
11 |
105,689,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01013:Tanc2
|
APN |
11 |
105,515,891 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01141:Tanc2
|
APN |
11 |
105,777,300 (GRCm39) |
splice site |
probably benign |
|
|
IGL01386:Tanc2
|
APN |
11 |
105,777,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01433:Tanc2
|
APN |
11 |
105,701,348 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01562:Tanc2
|
APN |
11 |
105,670,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01979:Tanc2
|
APN |
11 |
105,667,746 (GRCm39) |
missense |
probably benign |
|
|
IGL02104:Tanc2
|
APN |
11 |
105,670,959 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02434:Tanc2
|
APN |
11 |
105,670,868 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02534:Tanc2
|
APN |
11 |
105,725,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02568:Tanc2
|
APN |
11 |
105,667,777 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03279:Tanc2
|
APN |
11 |
105,803,918 (GRCm39) |
splice site |
probably null |
|
|
R0595:Tanc2
|
UTSW |
11 |
105,605,003 (GRCm39) |
splice site |
probably null |
|
|
R1131:Tanc2
|
UTSW |
11 |
105,725,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1320:Tanc2
|
UTSW |
11 |
105,777,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1487:Tanc2
|
UTSW |
11 |
105,814,460 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1497:Tanc2
|
UTSW |
11 |
105,812,963 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1692:Tanc2
|
UTSW |
11 |
105,748,326 (GRCm39) |
missense |
probably benign |
|
|
R1712:Tanc2
|
UTSW |
11 |
105,790,606 (GRCm39) |
missense |
probably benign |
|
|
R1793:Tanc2
|
UTSW |
11 |
105,515,859 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1812:Tanc2
|
UTSW |
11 |
105,777,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1905:Tanc2
|
UTSW |
11 |
105,813,689 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1959:Tanc2
|
UTSW |
11 |
105,801,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Tanc2
|
UTSW |
11 |
105,689,558 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2122:Tanc2
|
UTSW |
11 |
105,786,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Tanc2
|
UTSW |
11 |
105,801,135 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2341:Tanc2
|
UTSW |
11 |
105,725,877 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2497:Tanc2
|
UTSW |
11 |
105,564,319 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3438:Tanc2
|
UTSW |
11 |
105,748,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3711:Tanc2
|
UTSW |
11 |
105,689,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3765:Tanc2
|
UTSW |
11 |
105,805,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Tanc2
|
UTSW |
11 |
105,689,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Tanc2
|
UTSW |
11 |
105,804,888 (GRCm39) |
intron |
probably benign |
|
|
R4674:Tanc2
|
UTSW |
11 |
105,758,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4928:Tanc2
|
UTSW |
11 |
105,758,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Tanc2
|
UTSW |
11 |
105,515,886 (GRCm39) |
start codon destroyed |
probably null |
0.46 |
|
R5010:Tanc2
|
UTSW |
11 |
105,670,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5135:Tanc2
|
UTSW |
11 |
105,748,379 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5385:Tanc2
|
UTSW |
11 |
105,667,672 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5409:Tanc2
|
UTSW |
11 |
105,758,311 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5419:Tanc2
|
UTSW |
11 |
105,813,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5501:Tanc2
|
UTSW |
11 |
105,805,811 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5590:Tanc2
|
UTSW |
11 |
105,814,132 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5651:Tanc2
|
UTSW |
11 |
105,689,526 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5798:Tanc2
|
UTSW |
11 |
105,812,681 (GRCm39) |
small deletion |
probably benign |
|
|
R5876:Tanc2
|
UTSW |
11 |
105,813,439 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5889:Tanc2
|
UTSW |
11 |
105,812,633 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5958:Tanc2
|
UTSW |
11 |
105,731,451 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5999:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,814,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6024:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6025:Tanc2
|
UTSW |
11 |
105,787,373 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6025:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6048:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Tanc2
|
UTSW |
11 |
105,758,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6185:Tanc2
|
UTSW |
11 |
105,803,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6335:Tanc2
|
UTSW |
11 |
105,748,382 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6821:Tanc2
|
UTSW |
11 |
105,777,316 (GRCm39) |
splice site |
probably null |
|
|
R6846:Tanc2
|
UTSW |
11 |
105,689,479 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6857:Tanc2
|
UTSW |
11 |
105,801,114 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6904:Tanc2
|
UTSW |
11 |
105,726,056 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7009:Tanc2
|
UTSW |
11 |
105,731,525 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7017:Tanc2
|
UTSW |
11 |
105,813,934 (GRCm39) |
missense |
probably benign |
|
|
R7371:Tanc2
|
UTSW |
11 |
105,689,422 (GRCm39) |
missense |
probably benign |
|
|
R7556:Tanc2
|
UTSW |
11 |
105,799,857 (GRCm39) |
missense |
|
|
|
R7630:Tanc2
|
UTSW |
11 |
105,667,734 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7693:Tanc2
|
UTSW |
11 |
105,814,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Tanc2
|
UTSW |
11 |
105,667,684 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7807:Tanc2
|
UTSW |
11 |
105,758,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7878:Tanc2
|
UTSW |
11 |
105,804,241 (GRCm39) |
missense |
|
|
|
R7895:Tanc2
|
UTSW |
11 |
105,812,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Tanc2
|
UTSW |
11 |
105,787,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8099:Tanc2
|
UTSW |
11 |
105,754,833 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Tanc2
|
UTSW |
11 |
105,725,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8133:Tanc2
|
UTSW |
11 |
105,814,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8422:Tanc2
|
UTSW |
11 |
105,726,014 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8527:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8542:Tanc2
|
UTSW |
11 |
105,807,834 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8834:Tanc2
|
UTSW |
11 |
105,807,845 (GRCm39) |
missense |
|
|
|
R8912:Tanc2
|
UTSW |
11 |
105,758,153 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8927:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8928:Tanc2
|
UTSW |
11 |
105,701,331 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8968:Tanc2
|
UTSW |
11 |
105,758,400 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9065:Tanc2
|
UTSW |
11 |
105,689,518 (GRCm39) |
nonsense |
probably null |
|
|
R9095:Tanc2
|
UTSW |
11 |
105,758,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9108:Tanc2
|
UTSW |
11 |
105,810,580 (GRCm39) |
intron |
probably benign |
|
|
R9131:Tanc2
|
UTSW |
11 |
105,689,603 (GRCm39) |
missense |
probably benign |
|
|
R9294:Tanc2
|
UTSW |
11 |
105,777,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9445:Tanc2
|
UTSW |
11 |
105,758,290 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
X0027:Tanc2
|
UTSW |
11 |
105,726,009 (GRCm39) |
missense |
probably benign |
0.26 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTACAGAAAGTCTTAAGTAGGTTGC -3'
(R):5'- CAGGAGCATCTGGTTTTGCG -3'
Sequencing Primer
(F):5'- TTAAGTAGGTTGCTACAATAGAAAGC -3'
(R):5'- TTTGAACTCAGGACCTCTGGAAG -3'
|
| Posted On |
2015-09-25 |
Incidental Mutation