Incidental Mutation 'R4656:Adgb'
| ID |
352447 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgb
|
| Ensembl Gene |
ENSMUSG00000050994 |
| Gene Name |
androglobin |
| Synonyms |
9130014G24Rik |
| MMRRC Submission |
041916-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4656 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
10211447-10348070 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 10281050 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 656
(N656K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134378
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045328]
[ENSMUST00000132573]
[ENSMUST00000148816]
[ENSMUST00000172530]
[ENSMUST00000179956]
[ENSMUST00000208717]
|
| AlphaFold |
G3UZ78 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000045328
AA Change: N258K
PolyPhen 2
Score 0.922 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000045452
Gene: ENSMUSG00000050994
AA Change: N258K
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CysPc
|
11 |
257 |
1e-165 |
BLAST |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000132573
AA Change: N656K
PolyPhen 2
Score 0.871 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000120422
Gene: ENSMUSG00000050994
AA Change: N656K
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
655 |
2.7e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148816
|
| SMART Domains |
Protein: ENSMUSP00000133652
Gene: ENSMUSG00000050994
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CysPc
|
1 |
41 |
1e-19 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000172530
AA Change: N656K
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000134378
Gene: ENSMUSG00000050994
AA Change: N656K
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
655 |
2.7e-2 |
SMART |
|
IQ
|
904 |
926 |
6.41e0 |
SMART |
|
low complexity region
|
1179 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1318 |
1335 |
N/A |
INTRINSIC |
|
coiled coil region
|
1534 |
1559 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1633 |
N/A |
INTRINSIC |
|
low complexity region
|
1649 |
1657 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000179956
AA Change: N658K
PolyPhen 2
Score 0.952 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000136386
Gene: ENSMUSG00000050994
AA Change: N658K
| Domain | Start | End | E-Value | Type |
|---|
|
CysPc
|
56 |
657 |
5.36e-2 |
SMART |
|
IQ
|
906 |
928 |
6.41e0 |
SMART |
|
low complexity region
|
1181 |
1192 |
N/A |
INTRINSIC |
|
low complexity region
|
1321 |
1338 |
N/A |
INTRINSIC |
|
coiled coil region
|
1537 |
1562 |
N/A |
INTRINSIC |
|
low complexity region
|
1619 |
1636 |
N/A |
INTRINSIC |
|
low complexity region
|
1652 |
1660 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000208717
AA Change: N632K
PolyPhen 2
Score 0.842 (Sensitivity: 0.83; Specificity: 0.93)
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.5%
- 20x: 95.8%
|
| Validation Efficiency |
96% (80/83) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310003L06Rik |
G |
A |
5: 88,112,534 (GRCm39) |
|
probably benign |
Het |
| 4931406B18Rik |
T |
A |
7: 43,150,565 (GRCm39) |
H69L |
probably benign |
Het |
| Ace2 |
T |
C |
X: 162,936,110 (GRCm39) |
S84P |
probably benign |
Het |
| Ago3 |
G |
T |
4: 126,257,545 (GRCm39) |
Y495* |
probably null |
Het |
| Ahnak |
G |
A |
19: 8,982,219 (GRCm39) |
V1168M |
possibly damaging |
Het |
| Armc10 |
A |
G |
5: 21,866,548 (GRCm39) |
R271G |
probably benign |
Het |
| Atp4a |
T |
G |
7: 30,419,373 (GRCm39) |
|
probably benign |
Het |
| Casp1 |
C |
T |
9: 5,304,324 (GRCm39) |
P333S |
probably damaging |
Het |
| Ceacam9 |
C |
T |
7: 16,457,574 (GRCm39) |
A34V |
probably benign |
Het |
| Ces1b |
C |
G |
8: 93,784,042 (GRCm39) |
E488Q |
probably damaging |
Het |
| Ces2h |
A |
T |
8: 105,741,271 (GRCm39) |
T88S |
possibly damaging |
Het |
| Cfap410 |
G |
A |
10: 77,817,450 (GRCm39) |
R59H |
probably benign |
Het |
| Col2a1 |
C |
T |
15: 97,874,057 (GRCm39) |
G1375D |
unknown |
Het |
| Cyp1a1 |
T |
C |
9: 57,609,893 (GRCm39) |
F436L |
probably damaging |
Het |
| Dcaf7 |
T |
C |
11: 105,944,624 (GRCm39) |
V269A |
probably damaging |
Het |
| Disp2 |
T |
C |
2: 118,621,044 (GRCm39) |
L592P |
probably damaging |
Het |
| Eda2r |
T |
A |
X: 96,385,239 (GRCm39) |
Q171L |
probably damaging |
Het |
| Egln2 |
A |
G |
7: 26,858,618 (GRCm39) |
V408A |
probably benign |
Het |
| Gabpb2 |
A |
G |
3: 95,096,252 (GRCm39) |
L325P |
probably damaging |
Het |
| Gigyf1 |
C |
A |
5: 137,523,477 (GRCm39) |
Y936* |
probably null |
Het |
| Gm14149 |
A |
T |
2: 151,072,684 (GRCm39) |
|
noncoding transcript |
Het |
| Gnl2 |
C |
T |
4: 124,934,790 (GRCm39) |
Q149* |
probably null |
Het |
| Gpr107 |
C |
T |
2: 31,104,261 (GRCm39) |
T522M |
probably damaging |
Het |
| Grpr |
T |
A |
X: 162,297,992 (GRCm39) |
S351C |
probably damaging |
Het |
| Gsdma |
T |
C |
11: 98,563,907 (GRCm39) |
L287P |
probably damaging |
Het |
| Herc1 |
A |
G |
9: 66,301,993 (GRCm39) |
T652A |
probably damaging |
Het |
| Ifi204 |
C |
A |
1: 173,587,927 (GRCm39) |
|
probably benign |
Het |
| Irx2 |
T |
C |
13: 72,779,417 (GRCm39) |
S234P |
probably damaging |
Het |
| Itgal |
T |
A |
7: 126,921,725 (GRCm39) |
D808E |
probably damaging |
Het |
| Krt13 |
C |
A |
11: 100,010,189 (GRCm39) |
R264L |
probably damaging |
Het |
| Marchf1 |
T |
A |
8: 66,839,071 (GRCm39) |
L38I |
probably benign |
Het |
| Megf9 |
T |
C |
4: 70,367,004 (GRCm39) |
H326R |
probably damaging |
Het |
| Mif4gd |
G |
T |
11: 115,499,163 (GRCm39) |
|
probably benign |
Het |
| Mroh9 |
A |
T |
1: 162,893,593 (GRCm39) |
M194K |
probably damaging |
Het |
| Nhlrc3 |
A |
G |
3: 53,370,501 (GRCm39) |
S22P |
probably damaging |
Het |
| Nipal2 |
A |
T |
15: 34,577,714 (GRCm39) |
|
probably null |
Het |
| Nr1h4 |
A |
G |
10: 89,334,115 (GRCm39) |
S78P |
probably benign |
Het |
| Ofcc1 |
G |
A |
13: 40,168,864 (GRCm39) |
T841I |
probably damaging |
Het |
| Olfr908 |
A |
T |
9: 38,427,852 (GRCm39) |
N175Y |
probably damaging |
Het |
| Or1e30 |
A |
T |
11: 73,678,337 (GRCm39) |
D191V |
probably damaging |
Het |
| Or52d13 |
C |
T |
7: 103,109,695 (GRCm39) |
R235Q |
probably benign |
Het |
| Pdzd2 |
A |
G |
15: 12,385,797 (GRCm39) |
V991A |
probably benign |
Het |
| Pex1 |
G |
A |
5: 3,654,880 (GRCm39) |
|
probably null |
Het |
| Plch1 |
G |
T |
3: 63,611,598 (GRCm39) |
A859E |
probably damaging |
Het |
| Pramel32 |
T |
C |
4: 88,548,202 (GRCm39) |
T68A |
probably benign |
Het |
| Ranbp2 |
A |
G |
10: 58,289,244 (GRCm39) |
K84R |
possibly damaging |
Het |
| Rbm14 |
T |
C |
19: 4,861,463 (GRCm39) |
Y25C |
probably damaging |
Het |
| Rmi2 |
A |
G |
16: 10,653,186 (GRCm39) |
D78G |
probably damaging |
Het |
| Serpina3k |
C |
A |
12: 104,311,532 (GRCm39) |
T370K |
probably damaging |
Het |
| Shc2 |
A |
T |
10: 79,457,003 (GRCm39) |
L538M |
probably damaging |
Het |
| Skint1 |
A |
G |
4: 111,878,674 (GRCm39) |
K202R |
probably damaging |
Het |
| Slc22a29 |
C |
A |
19: 8,195,664 (GRCm39) |
S125I |
possibly damaging |
Het |
| Slc5a9 |
C |
A |
4: 111,748,941 (GRCm39) |
|
probably null |
Het |
| Slco4c1 |
A |
T |
1: 96,768,970 (GRCm39) |
D297E |
probably benign |
Het |
| Slco6d1 |
T |
C |
1: 98,350,928 (GRCm39) |
F136S |
probably benign |
Het |
| Smg1 |
A |
T |
7: 117,812,174 (GRCm39) |
V39E |
probably benign |
Het |
| Spns1 |
G |
T |
7: 125,973,474 (GRCm39) |
|
probably benign |
Het |
| Spsb1 |
A |
G |
4: 149,990,867 (GRCm39) |
|
probably null |
Het |
| Sspo |
T |
G |
6: 48,431,010 (GRCm39) |
I631S |
possibly damaging |
Het |
| Syne2 |
T |
C |
12: 76,078,147 (GRCm39) |
L4694P |
probably damaging |
Het |
| Taf5l |
T |
C |
8: 124,724,844 (GRCm39) |
E325G |
probably benign |
Het |
| Tars1 |
A |
T |
15: 11,394,350 (GRCm39) |
S96T |
probably damaging |
Het |
| Tdrd12 |
T |
C |
7: 35,184,679 (GRCm39) |
K745E |
probably damaging |
Het |
| Tenm3 |
A |
G |
8: 48,746,761 (GRCm39) |
Y1015H |
probably damaging |
Het |
| Trpv3 |
T |
A |
11: 73,186,240 (GRCm39) |
M677K |
probably damaging |
Het |
| Txlnb |
A |
T |
10: 17,691,024 (GRCm39) |
K191N |
probably damaging |
Het |
| Ubr1 |
A |
G |
2: 120,756,494 (GRCm39) |
V711A |
probably benign |
Het |
| Uqcrb |
T |
C |
13: 67,049,603 (GRCm39) |
T41A |
probably benign |
Het |
| Usp6nl |
A |
G |
2: 6,445,973 (GRCm39) |
Y627C |
probably damaging |
Het |
| Vezf1 |
A |
G |
11: 87,965,493 (GRCm39) |
D245G |
probably damaging |
Het |
| Vmn2r66 |
A |
G |
7: 84,661,204 (GRCm39) |
W9R |
possibly damaging |
Het |
| Wdr17 |
C |
T |
8: 55,134,434 (GRCm39) |
G349R |
probably damaging |
Het |
| Wdr35 |
T |
A |
12: 9,066,619 (GRCm39) |
M749K |
probably benign |
Het |
| Wrn |
A |
T |
8: 33,826,019 (GRCm39) |
|
probably null |
Het |
| Zfy1 |
T |
G |
Y: 729,626 (GRCm39) |
T339P |
unknown |
Het |
|
| Other mutations in Adgb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00503:Adgb
|
APN |
10 |
10,281,843 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01083:Adgb
|
APN |
10 |
10,283,298 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03064:Adgb
|
APN |
10 |
10,276,316 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0080:Adgb
|
UTSW |
10 |
10,253,583 (GRCm39) |
splice site |
probably benign |
|
|
R0084:Adgb
|
UTSW |
10 |
10,272,088 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R0112:Adgb
|
UTSW |
10 |
10,282,902 (GRCm39) |
splice site |
probably benign |
|
|
R0348:Adgb
|
UTSW |
10 |
10,233,623 (GRCm39) |
missense |
probably benign |
|
|
R0415:Adgb
|
UTSW |
10 |
10,306,811 (GRCm39) |
splice site |
probably null |
|
|
R0633:Adgb
|
UTSW |
10 |
10,267,473 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1052:Adgb
|
UTSW |
10 |
10,318,357 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1248:Adgb
|
UTSW |
10 |
10,271,054 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1278:Adgb
|
UTSW |
10 |
10,258,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1568:Adgb
|
UTSW |
10 |
10,318,409 (GRCm39) |
nonsense |
probably null |
|
|
R1647:Adgb
|
UTSW |
10 |
10,271,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1648:Adgb
|
UTSW |
10 |
10,271,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1663:Adgb
|
UTSW |
10 |
10,215,419 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1688:Adgb
|
UTSW |
10 |
10,226,061 (GRCm39) |
nonsense |
probably null |
|
|
R1758:Adgb
|
UTSW |
10 |
10,302,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1772:Adgb
|
UTSW |
10 |
10,258,465 (GRCm39) |
splice site |
probably benign |
|
|
R1850:Adgb
|
UTSW |
10 |
10,318,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1959:Adgb
|
UTSW |
10 |
10,270,993 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1980:Adgb
|
UTSW |
10 |
10,309,242 (GRCm39) |
missense |
probably benign |
|
|
R2179:Adgb
|
UTSW |
10 |
10,271,018 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2229:Adgb
|
UTSW |
10 |
10,311,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2283:Adgb
|
UTSW |
10 |
10,253,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2870:Adgb
|
UTSW |
10 |
10,307,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2870:Adgb
|
UTSW |
10 |
10,307,025 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2875:Adgb
|
UTSW |
10 |
10,298,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2876:Adgb
|
UTSW |
10 |
10,298,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2920:Adgb
|
UTSW |
10 |
10,265,987 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2931:Adgb
|
UTSW |
10 |
10,318,246 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R3722:Adgb
|
UTSW |
10 |
10,216,254 (GRCm39) |
missense |
probably benign |
0.32 |
|
R3846:Adgb
|
UTSW |
10 |
10,258,465 (GRCm39) |
splice site |
probably benign |
|
|
R3877:Adgb
|
UTSW |
10 |
10,318,227 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4210:Adgb
|
UTSW |
10 |
10,283,209 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4211:Adgb
|
UTSW |
10 |
10,283,209 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4333:Adgb
|
UTSW |
10 |
10,318,246 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4448:Adgb
|
UTSW |
10 |
10,266,569 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4470:Adgb
|
UTSW |
10 |
10,274,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4624:Adgb
|
UTSW |
10 |
10,278,748 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4676:Adgb
|
UTSW |
10 |
10,302,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Adgb
|
UTSW |
10 |
10,274,647 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4795:Adgb
|
UTSW |
10 |
10,233,616 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4858:Adgb
|
UTSW |
10 |
10,225,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4985:Adgb
|
UTSW |
10 |
10,276,376 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5057:Adgb
|
UTSW |
10 |
10,233,722 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5157:Adgb
|
UTSW |
10 |
10,274,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5209:Adgb
|
UTSW |
10 |
10,274,681 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5339:Adgb
|
UTSW |
10 |
10,318,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5376:Adgb
|
UTSW |
10 |
10,222,307 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5426:Adgb
|
UTSW |
10 |
10,226,004 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5516:Adgb
|
UTSW |
10 |
10,306,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5554:Adgb
|
UTSW |
10 |
10,216,217 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Adgb
|
UTSW |
10 |
10,307,070 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5707:Adgb
|
UTSW |
10 |
10,267,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5708:Adgb
|
UTSW |
10 |
10,267,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5891:Adgb
|
UTSW |
10 |
10,253,591 (GRCm39) |
nonsense |
probably null |
|
|
R5928:Adgb
|
UTSW |
10 |
10,254,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6005:Adgb
|
UTSW |
10 |
10,271,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6017:Adgb
|
UTSW |
10 |
10,325,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6049:Adgb
|
UTSW |
10 |
10,253,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6118:Adgb
|
UTSW |
10 |
10,307,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Adgb
|
UTSW |
10 |
10,274,687 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6186:Adgb
|
UTSW |
10 |
10,298,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6234:Adgb
|
UTSW |
10 |
10,228,824 (GRCm39) |
splice site |
probably null |
|
|
R6383:Adgb
|
UTSW |
10 |
10,325,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Adgb
|
UTSW |
10 |
10,253,636 (GRCm39) |
nonsense |
probably null |
|
|
R6639:Adgb
|
UTSW |
10 |
10,311,700 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R6697:Adgb
|
UTSW |
10 |
10,281,870 (GRCm39) |
nonsense |
probably null |
|
|
R6742:Adgb
|
UTSW |
10 |
10,287,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6745:Adgb
|
UTSW |
10 |
10,265,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6850:Adgb
|
UTSW |
10 |
10,270,318 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7128:Adgb
|
UTSW |
10 |
10,347,985 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7326:Adgb
|
UTSW |
10 |
10,276,318 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7386:Adgb
|
UTSW |
10 |
10,253,693 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7431:Adgb
|
UTSW |
10 |
10,267,699 (GRCm39) |
splice site |
probably null |
|
|
R7569:Adgb
|
UTSW |
10 |
10,306,996 (GRCm39) |
missense |
probably benign |
|
|
R7579:Adgb
|
UTSW |
10 |
10,286,562 (GRCm39) |
nonsense |
probably null |
|
|
R7582:Adgb
|
UTSW |
10 |
10,266,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7615:Adgb
|
UTSW |
10 |
10,311,754 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7692:Adgb
|
UTSW |
10 |
10,287,456 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7774:Adgb
|
UTSW |
10 |
10,215,404 (GRCm39) |
nonsense |
probably null |
|
|
R7808:Adgb
|
UTSW |
10 |
10,254,403 (GRCm39) |
splice site |
probably null |
|
|
R8158:Adgb
|
UTSW |
10 |
10,254,478 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8386:Adgb
|
UTSW |
10 |
10,226,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8746:Adgb
|
UTSW |
10 |
10,281,028 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8785:Adgb
|
UTSW |
10 |
10,233,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9089:Adgb
|
UTSW |
10 |
10,318,432 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9140:Adgb
|
UTSW |
10 |
10,216,263 (GRCm39) |
nonsense |
probably null |
|
|
R9386:Adgb
|
UTSW |
10 |
10,274,708 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9777:Adgb
|
UTSW |
10 |
10,283,214 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
X0003:Adgb
|
UTSW |
10 |
10,270,374 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Adgb
|
UTSW |
10 |
10,254,486 (GRCm39) |
missense |
probably benign |
0.09 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGCTCATGGTCTGGACAAG -3'
(R):5'- TGCTGCTGGGAGAAATACCG -3'
Sequencing Primer
(F):5'- CTCATGGTCTGGACAAGGGGTG -3'
(R):5'- CGGATGCATTGACTATCTATCCACAG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation