Incidental Mutation 'R4771:Usp24'
| ID |
367479 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Usp24
|
| Ensembl Gene |
ENSMUSG00000028514 |
| Gene Name |
ubiquitin specific peptidase 24 |
| Synonyms |
2700066K03Rik, 2810030C21Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4771 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
106173410-106298519 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 106219377 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133095
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094933]
[ENSMUST00000165709]
|
| AlphaFold |
B1AY13 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000094933
|
| SMART Domains |
Protein: ENSMUSP00000092538
Gene: ENSMUSG00000028514
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:UBA
|
5 |
43 |
2e-16 |
BLAST |
|
low complexity region
|
57 |
96 |
N/A |
INTRINSIC |
|
SCOP:d1gw5a_
|
348 |
882 |
6e-7 |
SMART |
|
low complexity region
|
1031 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1124 |
1150 |
N/A |
INTRINSIC |
|
low complexity region
|
1365 |
1378 |
N/A |
INTRINSIC |
|
Pfam:UCH
|
1685 |
2036 |
3.7e-54 |
PFAM |
|
Pfam:UCH_1
|
1686 |
1993 |
1.8e-27 |
PFAM |
|
low complexity region
|
2066 |
2081 |
N/A |
INTRINSIC |
|
low complexity region
|
2256 |
2267 |
N/A |
INTRINSIC |
|
low complexity region
|
2576 |
2592 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000106798
|
| SMART Domains |
Protein: ENSMUSP00000102410
Gene: ENSMUSG00000028514
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ifya_
|
3 |
47 |
2e-6 |
SMART |
|
Blast:UBA
|
5 |
43 |
2e-17 |
BLAST |
|
low complexity region
|
57 |
96 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000165709
|
| SMART Domains |
Protein: ENSMUSP00000133095
Gene: ENSMUSG00000028514
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:UBA
|
5 |
43 |
2e-16 |
BLAST |
|
low complexity region
|
57 |
96 |
N/A |
INTRINSIC |
|
SCOP:d1gw5a_
|
348 |
883 |
8e-7 |
SMART |
|
low complexity region
|
1032 |
1060 |
N/A |
INTRINSIC |
|
low complexity region
|
1125 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1379 |
N/A |
INTRINSIC |
|
Pfam:UCH
|
1686 |
2037 |
2e-49 |
PFAM |
|
Pfam:UCH_1
|
1687 |
1994 |
4e-24 |
PFAM |
|
low complexity region
|
2067 |
2082 |
N/A |
INTRINSIC |
|
low complexity region
|
2257 |
2268 |
N/A |
INTRINSIC |
|
low complexity region
|
2577 |
2593 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022B05Rik |
T |
C |
8: 125,366,300 (GRCm39) |
T148A |
probably benign |
Het |
| Abcc4 |
G |
T |
14: 118,721,796 (GRCm39) |
N1234K |
probably benign |
Het |
| Adamts20 |
C |
T |
15: 94,249,516 (GRCm39) |
|
probably null |
Het |
| Aqp9 |
C |
T |
9: 71,030,152 (GRCm39) |
G212S |
probably damaging |
Het |
| Asb15 |
A |
T |
6: 24,570,621 (GRCm39) |
N533I |
probably damaging |
Het |
| Brwd1 |
A |
G |
16: 95,804,518 (GRCm39) |
V1884A |
probably benign |
Het |
| Ccdc106 |
G |
A |
7: 5,060,521 (GRCm39) |
|
probably null |
Het |
| Cfap46 |
A |
T |
7: 139,210,524 (GRCm39) |
L1774Q |
probably null |
Het |
| Cfap95 |
A |
G |
19: 23,536,337 (GRCm39) |
L190P |
probably damaging |
Het |
| Cibar1 |
T |
A |
4: 12,155,689 (GRCm39) |
Q311L |
probably benign |
Het |
| Clec2h |
G |
A |
6: 128,651,118 (GRCm39) |
E133K |
probably damaging |
Het |
| Cntn1 |
T |
A |
15: 92,202,972 (GRCm39) |
F751L |
possibly damaging |
Het |
| Col20a1 |
A |
T |
2: 180,630,917 (GRCm39) |
M62L |
probably benign |
Het |
| Col7a1 |
T |
C |
9: 108,800,993 (GRCm39) |
V1899A |
probably damaging |
Het |
| Cpa5 |
T |
A |
6: 30,612,684 (GRCm39) |
L28* |
probably null |
Het |
| Crb1 |
T |
A |
1: 139,255,942 (GRCm39) |
E264D |
probably damaging |
Het |
| Creb3l2 |
A |
T |
6: 37,311,512 (GRCm39) |
S426T |
probably benign |
Het |
| Cspg5 |
T |
A |
9: 110,080,195 (GRCm39) |
N373K |
probably damaging |
Het |
| Ctso |
T |
C |
3: 81,840,047 (GRCm39) |
S26P |
probably benign |
Het |
| Depdc1b |
A |
C |
13: 108,519,434 (GRCm39) |
D348A |
probably benign |
Het |
| Diaph1 |
A |
T |
18: 37,986,604 (GRCm39) |
M1127K |
probably damaging |
Het |
| Dlgap1 |
A |
T |
17: 70,900,375 (GRCm39) |
K397* |
probably null |
Het |
| Dock3 |
T |
A |
9: 106,829,557 (GRCm39) |
H1119L |
possibly damaging |
Het |
| Dok4 |
G |
T |
8: 95,591,795 (GRCm39) |
|
probably null |
Het |
| Dram2 |
A |
G |
3: 106,480,361 (GRCm39) |
T225A |
probably damaging |
Het |
| Dst |
G |
A |
1: 34,288,565 (GRCm39) |
R5603H |
probably damaging |
Het |
| Ehbp1l1 |
A |
G |
19: 5,775,996 (GRCm39) |
F18S |
probably damaging |
Het |
| Epha5 |
A |
G |
5: 84,298,278 (GRCm39) |
V427A |
probably damaging |
Het |
| Exoc4 |
A |
T |
6: 33,418,884 (GRCm39) |
|
probably null |
Het |
| Exph5 |
C |
T |
9: 53,284,965 (GRCm39) |
T682I |
possibly damaging |
Het |
| Fnbp1l |
A |
T |
3: 122,351,752 (GRCm39) |
S264T |
possibly damaging |
Het |
| Ggnbp2 |
A |
T |
11: 84,725,314 (GRCm39) |
D580E |
probably benign |
Het |
| Gm10277 |
G |
A |
11: 77,676,534 (GRCm39) |
|
probably benign |
Het |
| Golm2 |
T |
A |
2: 121,756,126 (GRCm39) |
V352E |
probably damaging |
Het |
| Gtf2a1l |
C |
A |
17: 88,997,448 (GRCm39) |
P93Q |
probably benign |
Het |
| Hydin |
A |
T |
8: 111,259,515 (GRCm39) |
I2496F |
probably benign |
Het |
| Ighv7-2 |
A |
C |
12: 113,876,087 (GRCm39) |
I6S |
probably benign |
Het |
| Irs1 |
A |
G |
1: 82,265,696 (GRCm39) |
V840A |
probably benign |
Het |
| Itgal |
A |
G |
7: 126,927,405 (GRCm39) |
E965G |
probably damaging |
Het |
| Izumo1 |
T |
G |
7: 45,272,233 (GRCm39) |
F5V |
probably benign |
Het |
| Izumo1 |
T |
A |
7: 45,272,234 (GRCm39) |
F5Y |
probably damaging |
Het |
| Kif13a |
A |
G |
13: 46,978,687 (GRCm39) |
S175P |
probably damaging |
Het |
| Klf14 |
A |
G |
6: 30,934,960 (GRCm39) |
F225L |
probably damaging |
Het |
| Kpna1 |
T |
C |
16: 35,853,773 (GRCm39) |
Y468H |
probably damaging |
Het |
| Krt5 |
T |
A |
15: 101,617,494 (GRCm39) |
Q413L |
probably damaging |
Het |
| Lbr |
T |
C |
1: 181,665,986 (GRCm39) |
Y41C |
probably damaging |
Het |
| Lmcd1 |
A |
T |
6: 112,292,834 (GRCm39) |
N229Y |
probably damaging |
Het |
| Marchf3 |
T |
A |
18: 56,916,170 (GRCm39) |
H175L |
probably benign |
Het |
| Mcmbp |
A |
G |
7: 128,300,124 (GRCm39) |
|
probably null |
Het |
| Med27 |
T |
A |
2: 29,303,515 (GRCm39) |
L16Q |
probably damaging |
Het |
| Mex3b |
A |
T |
7: 82,518,273 (GRCm39) |
Q196L |
possibly damaging |
Het |
| Mga |
T |
C |
2: 119,794,775 (GRCm39) |
S2820P |
probably damaging |
Het |
| Mroh2a |
C |
T |
1: 88,179,087 (GRCm39) |
L1104F |
probably damaging |
Het |
| Mta3 |
A |
G |
17: 84,063,103 (GRCm39) |
E166G |
probably damaging |
Het |
| Mthfd2l |
A |
G |
5: 91,096,727 (GRCm39) |
E116G |
possibly damaging |
Het |
| Musk |
A |
G |
4: 58,301,706 (GRCm39) |
I155V |
probably benign |
Het |
| Myh7b |
G |
A |
2: 155,468,314 (GRCm39) |
W834* |
probably null |
Het |
| Myo18b |
T |
A |
5: 112,840,093 (GRCm39) |
R2567* |
probably null |
Het |
| Nars2 |
A |
T |
7: 96,684,452 (GRCm39) |
E325V |
probably damaging |
Het |
| Nploc4 |
A |
G |
11: 120,312,260 (GRCm39) |
V106A |
possibly damaging |
Het |
| Nudcd1 |
A |
T |
15: 44,268,878 (GRCm39) |
S167R |
probably damaging |
Het |
| Nup133 |
T |
A |
8: 124,656,137 (GRCm39) |
D448V |
probably damaging |
Het |
| Or5al1 |
G |
T |
2: 85,990,417 (GRCm39) |
T99N |
probably benign |
Het |
| Or5p70 |
A |
T |
7: 107,995,229 (GRCm39) |
K301* |
probably null |
Het |
| Pax6 |
C |
A |
2: 105,526,847 (GRCm39) |
P251Q |
probably benign |
Het |
| Pcdh8 |
C |
T |
14: 80,005,710 (GRCm39) |
A893T |
possibly damaging |
Het |
| Per3 |
A |
T |
4: 151,093,716 (GRCm39) |
V1033E |
probably damaging |
Het |
| Polr1e |
T |
C |
4: 45,019,282 (GRCm39) |
S44P |
probably damaging |
Het |
| Pou4f2 |
T |
A |
8: 79,161,865 (GRCm39) |
H246L |
possibly damaging |
Het |
| Psmd2 |
G |
A |
16: 20,481,429 (GRCm39) |
R828Q |
probably damaging |
Het |
| Ptprq |
A |
G |
10: 107,524,288 (GRCm39) |
S482P |
probably benign |
Het |
| Rbm14 |
G |
T |
19: 4,852,671 (GRCm39) |
|
probably benign |
Het |
| Reln |
T |
C |
5: 22,254,698 (GRCm39) |
D557G |
probably damaging |
Het |
| Rhobtb2 |
A |
G |
14: 70,034,499 (GRCm39) |
I242T |
probably benign |
Het |
| Runx1 |
C |
A |
16: 92,492,629 (GRCm39) |
V5L |
possibly damaging |
Het |
| Shld2 |
G |
A |
14: 33,990,663 (GRCm39) |
T81M |
probably damaging |
Het |
| Slc13a1 |
A |
T |
6: 24,100,339 (GRCm39) |
Y381* |
probably null |
Het |
| Smyd3 |
A |
T |
1: 178,921,961 (GRCm39) |
C180S |
probably damaging |
Het |
| Sntg2 |
T |
A |
12: 30,326,658 (GRCm39) |
|
probably null |
Het |
| Snx19 |
G |
A |
9: 30,344,934 (GRCm39) |
V678I |
probably damaging |
Het |
| Spag5 |
G |
A |
11: 78,195,592 (GRCm39) |
A300T |
probably damaging |
Het |
| Spdl1 |
T |
A |
11: 34,704,154 (GRCm39) |
R560W |
probably damaging |
Het |
| Spen |
T |
C |
4: 141,199,907 (GRCm39) |
T2884A |
probably benign |
Het |
| Spg11 |
G |
A |
2: 121,895,963 (GRCm39) |
Q1752* |
probably null |
Het |
| Srrm4 |
C |
A |
5: 116,613,234 (GRCm39) |
|
probably null |
Het |
| Ssc4d |
A |
G |
5: 135,999,074 (GRCm39) |
L43P |
probably damaging |
Het |
| Sspo |
A |
G |
6: 48,437,813 (GRCm39) |
D1324G |
probably damaging |
Het |
| Tkt |
T |
G |
14: 30,288,982 (GRCm39) |
I238S |
probably damaging |
Het |
| Tmem184b |
A |
T |
15: 79,261,377 (GRCm39) |
N76K |
probably benign |
Het |
| Trpm6 |
A |
G |
19: 18,790,857 (GRCm39) |
M631V |
probably damaging |
Het |
| Ttll6 |
A |
C |
11: 96,024,655 (GRCm39) |
E15A |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,569,296 (GRCm39) |
D27199G |
probably damaging |
Het |
| Ubn2 |
A |
T |
6: 38,464,088 (GRCm39) |
|
probably null |
Het |
| Ubr5 |
A |
C |
15: 38,018,541 (GRCm39) |
I866M |
possibly damaging |
Het |
| Urb1 |
T |
C |
16: 90,550,406 (GRCm39) |
T2149A |
probably benign |
Het |
| Ush2a |
G |
T |
1: 188,529,966 (GRCm39) |
V3252L |
possibly damaging |
Het |
| Vill |
T |
A |
9: 118,897,502 (GRCm39) |
M259K |
probably damaging |
Het |
| Vldlr |
T |
C |
19: 27,217,290 (GRCm39) |
I411T |
probably damaging |
Het |
| Vmn2r120 |
A |
T |
17: 57,831,887 (GRCm39) |
W301R |
probably damaging |
Het |
| Vps13b |
G |
A |
15: 35,910,946 (GRCm39) |
S3570N |
probably damaging |
Het |
| Vps13c |
T |
C |
9: 67,836,821 (GRCm39) |
V1773A |
probably benign |
Het |
| Vtn |
A |
G |
11: 78,392,400 (GRCm39) |
D326G |
probably benign |
Het |
| Wdr93 |
A |
T |
7: 79,426,511 (GRCm39) |
H592L |
probably damaging |
Het |
| Zdhhc19 |
A |
G |
16: 32,317,953 (GRCm39) |
D94G |
probably damaging |
Het |
| Zfand4 |
A |
T |
6: 116,291,311 (GRCm39) |
E188V |
probably damaging |
Het |
| Zfp523 |
C |
A |
17: 28,420,312 (GRCm39) |
|
probably null |
Het |
| Zfp536 |
T |
C |
7: 37,268,309 (GRCm39) |
D369G |
probably damaging |
Het |
| Zfp608 |
T |
A |
18: 55,121,372 (GRCm39) |
T72S |
probably benign |
Het |
| Zfp804a |
T |
A |
2: 82,088,286 (GRCm39) |
V705E |
probably benign |
Het |
| Zfp974 |
T |
C |
7: 27,625,733 (GRCm39) |
T46A |
probably damaging |
Het |
| Zkscan4 |
C |
T |
13: 21,663,416 (GRCm39) |
Q52* |
probably null |
Het |
|
| Other mutations in Usp24 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00329:Usp24
|
APN |
4 |
106,216,288 (GRCm39) |
missense |
probably benign |
|
|
IGL00340:Usp24
|
APN |
4 |
106,258,336 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00480:Usp24
|
APN |
4 |
106,225,303 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00548:Usp24
|
APN |
4 |
106,198,495 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00655:Usp24
|
APN |
4 |
106,247,515 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00674:Usp24
|
APN |
4 |
106,229,876 (GRCm39) |
splice site |
probably benign |
|
|
IGL00718:Usp24
|
APN |
4 |
106,266,901 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL00803:Usp24
|
APN |
4 |
106,242,723 (GRCm39) |
splice site |
probably benign |
|
|
IGL01161:Usp24
|
APN |
4 |
106,294,041 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01344:Usp24
|
APN |
4 |
106,236,582 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01374:Usp24
|
APN |
4 |
106,237,296 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL01485:Usp24
|
APN |
4 |
106,219,429 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01736:Usp24
|
APN |
4 |
106,280,658 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01737:Usp24
|
APN |
4 |
106,244,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01862:Usp24
|
APN |
4 |
106,266,095 (GRCm39) |
splice site |
probably benign |
|
|
IGL01981:Usp24
|
APN |
4 |
106,232,965 (GRCm39) |
splice site |
probably benign |
|
|
IGL02090:Usp24
|
APN |
4 |
106,268,623 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL02275:Usp24
|
APN |
4 |
106,244,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02352:Usp24
|
APN |
4 |
106,261,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02359:Usp24
|
APN |
4 |
106,261,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02391:Usp24
|
APN |
4 |
106,264,326 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
IGL02418:Usp24
|
APN |
4 |
106,293,557 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02537:Usp24
|
APN |
4 |
106,249,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02638:Usp24
|
APN |
4 |
106,295,969 (GRCm39) |
splice site |
probably benign |
|
|
IGL02638:Usp24
|
APN |
4 |
106,295,967 (GRCm39) |
splice site |
probably benign |
|
|
IGL02830:Usp24
|
APN |
4 |
106,204,584 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL03125:Usp24
|
APN |
4 |
106,249,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03280:Usp24
|
APN |
4 |
106,237,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03350:Usp24
|
APN |
4 |
106,228,276 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Usp24
|
UTSW |
4 |
106,285,686 (GRCm39) |
missense |
probably benign |
|
|
BB020:Usp24
|
UTSW |
4 |
106,285,686 (GRCm39) |
missense |
probably benign |
|
|
IGL03098:Usp24
|
UTSW |
4 |
106,228,230 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0035:Usp24
|
UTSW |
4 |
106,225,224 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0044:Usp24
|
UTSW |
4 |
106,269,281 (GRCm39) |
splice site |
probably benign |
|
|
R0086:Usp24
|
UTSW |
4 |
106,249,557 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0125:Usp24
|
UTSW |
4 |
106,254,496 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0197:Usp24
|
UTSW |
4 |
106,264,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0240:Usp24
|
UTSW |
4 |
106,271,601 (GRCm39) |
nonsense |
probably null |
|
|
R0240:Usp24
|
UTSW |
4 |
106,271,601 (GRCm39) |
nonsense |
probably null |
|
|
R0491:Usp24
|
UTSW |
4 |
106,259,302 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0687:Usp24
|
UTSW |
4 |
106,277,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Usp24
|
UTSW |
4 |
106,270,875 (GRCm39) |
splice site |
probably null |
|
|
R0973:Usp24
|
UTSW |
4 |
106,228,276 (GRCm39) |
nonsense |
probably null |
|
|
R0973:Usp24
|
UTSW |
4 |
106,228,276 (GRCm39) |
nonsense |
probably null |
|
|
R0974:Usp24
|
UTSW |
4 |
106,270,875 (GRCm39) |
splice site |
probably null |
|
|
R0974:Usp24
|
UTSW |
4 |
106,228,276 (GRCm39) |
nonsense |
probably null |
|
|
R1163:Usp24
|
UTSW |
4 |
106,278,157 (GRCm39) |
missense |
probably benign |
|
|
R1293:Usp24
|
UTSW |
4 |
106,280,750 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1333:Usp24
|
UTSW |
4 |
106,199,550 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1476:Usp24
|
UTSW |
4 |
106,219,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1699:Usp24
|
UTSW |
4 |
106,296,024 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1728:Usp24
|
UTSW |
4 |
106,217,618 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1729:Usp24
|
UTSW |
4 |
106,217,618 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1753:Usp24
|
UTSW |
4 |
106,234,756 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1917:Usp24
|
UTSW |
4 |
106,267,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2045:Usp24
|
UTSW |
4 |
106,258,177 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R2424:Usp24
|
UTSW |
4 |
106,256,310 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2436:Usp24
|
UTSW |
4 |
106,266,842 (GRCm39) |
nonsense |
probably null |
|
|
R2513:Usp24
|
UTSW |
4 |
106,236,602 (GRCm39) |
splice site |
probably null |
|
|
R3824:Usp24
|
UTSW |
4 |
106,236,263 (GRCm39) |
missense |
probably benign |
|
|
R3831:Usp24
|
UTSW |
4 |
106,219,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3833:Usp24
|
UTSW |
4 |
106,219,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3982:Usp24
|
UTSW |
4 |
106,245,080 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4022:Usp24
|
UTSW |
4 |
106,236,421 (GRCm39) |
splice site |
probably benign |
|
|
R4067:Usp24
|
UTSW |
4 |
106,216,286 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4175:Usp24
|
UTSW |
4 |
106,173,970 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4766:Usp24
|
UTSW |
4 |
106,273,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4798:Usp24
|
UTSW |
4 |
106,217,359 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4809:Usp24
|
UTSW |
4 |
106,270,873 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4822:Usp24
|
UTSW |
4 |
106,273,244 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4906:Usp24
|
UTSW |
4 |
106,245,834 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4934:Usp24
|
UTSW |
4 |
106,283,743 (GRCm39) |
missense |
probably benign |
0.29 |
|
R5074:Usp24
|
UTSW |
4 |
106,277,644 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5151:Usp24
|
UTSW |
4 |
106,256,309 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5220:Usp24
|
UTSW |
4 |
106,239,500 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5279:Usp24
|
UTSW |
4 |
106,242,621 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5280:Usp24
|
UTSW |
4 |
106,198,411 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5285:Usp24
|
UTSW |
4 |
106,264,230 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5292:Usp24
|
UTSW |
4 |
106,275,460 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5294:Usp24
|
UTSW |
4 |
106,219,554 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5394:Usp24
|
UTSW |
4 |
106,265,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5517:Usp24
|
UTSW |
4 |
106,232,871 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5522:Usp24
|
UTSW |
4 |
106,229,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5546:Usp24
|
UTSW |
4 |
106,273,244 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5756:Usp24
|
UTSW |
4 |
106,219,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5910:Usp24
|
UTSW |
4 |
106,237,665 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5972:Usp24
|
UTSW |
4 |
106,225,264 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6285:Usp24
|
UTSW |
4 |
106,231,297 (GRCm39) |
splice site |
probably null |
|
|
R6370:Usp24
|
UTSW |
4 |
106,237,718 (GRCm39) |
missense |
probably null |
0.20 |
|
R6630:Usp24
|
UTSW |
4 |
106,245,032 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6754:Usp24
|
UTSW |
4 |
106,217,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7027:Usp24
|
UTSW |
4 |
106,219,441 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7088:Usp24
|
UTSW |
4 |
106,244,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7129:Usp24
|
UTSW |
4 |
106,219,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7131:Usp24
|
UTSW |
4 |
106,239,500 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7156:Usp24
|
UTSW |
4 |
106,245,116 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7174:Usp24
|
UTSW |
4 |
106,219,878 (GRCm39) |
splice site |
probably null |
|
|
R7236:Usp24
|
UTSW |
4 |
106,263,502 (GRCm39) |
splice site |
probably null |
|
|
R7403:Usp24
|
UTSW |
4 |
106,264,232 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7424:Usp24
|
UTSW |
4 |
106,236,304 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7475:Usp24
|
UTSW |
4 |
106,199,550 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R7505:Usp24
|
UTSW |
4 |
106,236,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Usp24
|
UTSW |
4 |
106,173,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7900:Usp24
|
UTSW |
4 |
106,266,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Usp24
|
UTSW |
4 |
106,285,686 (GRCm39) |
missense |
probably benign |
|
|
R7940:Usp24
|
UTSW |
4 |
106,287,741 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8271:Usp24
|
UTSW |
4 |
106,285,711 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8348:Usp24
|
UTSW |
4 |
106,225,933 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8448:Usp24
|
UTSW |
4 |
106,225,933 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8483:Usp24
|
UTSW |
4 |
106,230,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8546:Usp24
|
UTSW |
4 |
106,259,326 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8798:Usp24
|
UTSW |
4 |
106,236,436 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8822:Usp24
|
UTSW |
4 |
106,269,410 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8992:Usp24
|
UTSW |
4 |
106,234,762 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9002:Usp24
|
UTSW |
4 |
106,275,412 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9037:Usp24
|
UTSW |
4 |
106,236,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9068:Usp24
|
UTSW |
4 |
106,232,875 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9096:Usp24
|
UTSW |
4 |
106,254,508 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9180:Usp24
|
UTSW |
4 |
106,216,247 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9199:Usp24
|
UTSW |
4 |
106,244,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9201:Usp24
|
UTSW |
4 |
106,277,727 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9251:Usp24
|
UTSW |
4 |
106,217,715 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9423:Usp24
|
UTSW |
4 |
106,288,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9459:Usp24
|
UTSW |
4 |
106,199,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9472:Usp24
|
UTSW |
4 |
106,261,128 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9483:Usp24
|
UTSW |
4 |
106,219,379 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9534:Usp24
|
UTSW |
4 |
106,264,312 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9653:Usp24
|
UTSW |
4 |
106,204,564 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9712:Usp24
|
UTSW |
4 |
106,204,564 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0024:Usp24
|
UTSW |
4 |
106,217,643 (GRCm39) |
missense |
probably benign |
0.09 |
|
X0028:Usp24
|
UTSW |
4 |
106,225,252 (GRCm39) |
missense |
probably benign |
0.01 |
|
X0066:Usp24
|
UTSW |
4 |
106,212,928 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCAGCTGTGAAGTTTAATGCAG -3'
(R):5'- AGAGGACATCTAACACCTGAAATAG -3'
Sequencing Primer
(F):5'- CTGTGAAGTTTAATGCAGACCAGC -3'
(R):5'- TAGCACCAGATGATGAGCCAGC -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation