Incidental Mutation 'R7237:Magi3'
| ID |
562880 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| MMRRC Submission |
045344-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R7237 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 103935227 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 902
(D902G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067932
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
[ENSMUST00000145727]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000064371
AA Change: D902G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
AA Change: D902G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000121198
AA Change: D902G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: D902G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000122303
AA Change: D902G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
AA Change: D902G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145727
|
| SMART Domains |
Protein: ENSMUSP00000114722
Gene: ENSMUSG00000058388
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Phtf-FEM1B_bdg
|
3 |
158 |
1.6e-88 |
PFAM |
|
low complexity region
|
170 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
347 |
370 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
512 |
534 |
N/A |
INTRINSIC |
|
transmembrane domain
|
610 |
632 |
N/A |
INTRINSIC |
|
transmembrane domain
|
647 |
664 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
98% (83/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Arhgap21 |
A |
T |
2: 20,854,783 (GRCm39) |
C1536* |
probably null |
Het |
| Armc9 |
C |
A |
1: 86,092,571 (GRCm39) |
Q169K |
possibly damaging |
Het |
| Aspm |
T |
A |
1: 139,405,667 (GRCm39) |
M1518K |
possibly damaging |
Het |
| AU018091 |
A |
G |
7: 3,209,006 (GRCm39) |
I360T |
probably benign |
Het |
| BB014433 |
C |
A |
8: 15,091,765 (GRCm39) |
V363L |
probably benign |
Het |
| Bcam |
T |
C |
7: 19,503,232 (GRCm39) |
|
probably null |
Het |
| Cacna1g |
T |
C |
11: 94,328,705 (GRCm39) |
S1071G |
probably benign |
Het |
| Card9 |
A |
T |
2: 26,246,787 (GRCm39) |
S354T |
probably benign |
Het |
| Ccdc87 |
A |
G |
19: 4,889,790 (GRCm39) |
N94S |
probably benign |
Het |
| Cdc27 |
A |
G |
11: 104,408,245 (GRCm39) |
V555A |
probably benign |
Het |
| Coro1a |
T |
A |
7: 126,299,478 (GRCm39) |
D411V |
probably benign |
Het |
| Cybrd1 |
GGTCCTGCAC |
G |
2: 70,948,553 (GRCm39) |
|
probably benign |
Het |
| Cyth1 |
A |
T |
11: 118,076,321 (GRCm39) |
I95N |
probably damaging |
Het |
| Dnah7b |
A |
T |
1: 46,179,126 (GRCm39) |
E933V |
probably damaging |
Het |
| Dync2h1 |
A |
T |
9: 6,993,966 (GRCm39) |
I3968N |
probably benign |
Het |
| Fam184a |
T |
C |
10: 53,510,489 (GRCm39) |
|
probably benign |
Het |
| Fat3 |
G |
A |
9: 16,288,510 (GRCm39) |
L338F |
probably damaging |
Het |
| Fcgr3 |
A |
G |
1: 170,886,870 (GRCm39) |
L18P |
probably damaging |
Het |
| Gbp5 |
T |
C |
3: 142,213,461 (GRCm39) |
V459A |
probably benign |
Het |
| Gja4 |
A |
T |
4: 127,205,956 (GRCm39) |
M269K |
probably benign |
Het |
| Gm4787 |
A |
G |
12: 81,424,442 (GRCm39) |
V572A |
probably damaging |
Het |
| Grin2d |
G |
T |
7: 45,515,600 (GRCm39) |
S131* |
probably null |
Het |
| Gys1 |
A |
G |
7: 45,104,586 (GRCm39) |
D671G |
probably benign |
Het |
| Haspin |
T |
C |
11: 73,027,712 (GRCm39) |
N459S |
probably benign |
Het |
| Hdac10 |
G |
T |
15: 89,009,580 (GRCm39) |
Q451K |
probably benign |
Het |
| Hdac9 |
T |
C |
12: 34,424,139 (GRCm39) |
|
probably null |
Het |
| Hmcn1 |
A |
G |
1: 150,598,394 (GRCm39) |
V1636A |
probably damaging |
Het |
| Hpca |
A |
G |
4: 129,012,407 (GRCm39) |
L43P |
probably damaging |
Het |
| Hycc2 |
G |
A |
1: 58,569,107 (GRCm39) |
Q491* |
probably null |
Het |
| Insm1 |
C |
A |
2: 146,064,448 (GRCm39) |
A88E |
possibly damaging |
Het |
| Itga9 |
A |
G |
9: 118,465,670 (GRCm39) |
K175E |
probably benign |
Het |
| Kif13a |
A |
G |
13: 46,962,632 (GRCm39) |
|
probably null |
Het |
| Kif20b |
T |
A |
19: 34,928,005 (GRCm39) |
L1089H |
probably damaging |
Het |
| Lamp5 |
A |
T |
2: 135,901,755 (GRCm39) |
H152L |
probably benign |
Het |
| Lrp4 |
T |
C |
2: 91,303,528 (GRCm39) |
F76L |
probably benign |
Het |
| Map10 |
C |
T |
8: 126,397,963 (GRCm39) |
P452L |
probably benign |
Het |
| Mapk6 |
A |
G |
9: 75,304,895 (GRCm39) |
L174P |
probably damaging |
Het |
| Meak7 |
C |
T |
8: 120,489,054 (GRCm39) |
G410S |
probably damaging |
Het |
| Ndufa4 |
C |
T |
6: 11,906,018 (GRCm39) |
|
probably null |
Het |
| Nedd4 |
A |
T |
9: 72,632,346 (GRCm39) |
E393D |
probably benign |
Het |
| Nlrp4b |
G |
A |
7: 10,449,143 (GRCm39) |
V449I |
probably benign |
Het |
| Nufip2 |
T |
A |
11: 77,583,596 (GRCm39) |
N503K |
probably benign |
Het |
| Or10ac1 |
T |
C |
6: 42,515,581 (GRCm39) |
D125G |
probably damaging |
Het |
| Or6y1 |
C |
T |
1: 174,276,905 (GRCm39) |
R239C |
probably benign |
Het |
| P4ha1 |
A |
G |
10: 59,184,065 (GRCm39) |
T176A |
probably benign |
Het |
| Palm3 |
A |
G |
8: 84,756,117 (GRCm39) |
K543R |
probably benign |
Het |
| Parvg |
G |
A |
15: 84,225,557 (GRCm39) |
A302T |
probably benign |
Het |
| Pcdh15 |
A |
G |
10: 74,420,023 (GRCm39) |
D1227G |
possibly damaging |
Het |
| Pdzd8 |
C |
T |
19: 59,333,571 (GRCm39) |
G150D |
probably damaging |
Het |
| Pitpnm2 |
A |
G |
5: 124,263,360 (GRCm39) |
|
probably null |
Het |
| Pld5 |
T |
C |
1: 176,102,301 (GRCm39) |
Q47R |
possibly damaging |
Het |
| Ppp2r5d |
T |
C |
17: 46,997,206 (GRCm39) |
S329G |
possibly damaging |
Het |
| Prss56 |
T |
C |
1: 87,112,637 (GRCm39) |
V144A |
probably damaging |
Het |
| Psg28 |
A |
T |
7: 18,161,769 (GRCm39) |
Y245N |
possibly damaging |
Het |
| Ptpn3 |
C |
T |
4: 57,239,625 (GRCm39) |
V302I |
probably damaging |
Het |
| Ptprn2 |
A |
G |
12: 117,125,347 (GRCm39) |
H627R |
probably benign |
Het |
| Rasgrp2 |
A |
T |
19: 6,454,838 (GRCm39) |
H226L |
possibly damaging |
Het |
| Rbm20 |
C |
T |
19: 53,839,930 (GRCm39) |
T973M |
probably benign |
Het |
| Rigi |
T |
A |
4: 40,205,938 (GRCm39) |
I885F |
probably benign |
Het |
| Riok2 |
T |
A |
17: 17,598,045 (GRCm39) |
L44Q |
probably damaging |
Het |
| Rusc1 |
G |
T |
3: 88,998,805 (GRCm39) |
Q326K |
possibly damaging |
Het |
| Rxylt1 |
A |
T |
10: 121,917,523 (GRCm39) |
L330* |
probably null |
Het |
| Sart3 |
A |
T |
5: 113,892,307 (GRCm39) |
H397Q |
possibly damaging |
Het |
| Sec31b |
T |
A |
19: 44,506,147 (GRCm39) |
T920S |
probably damaging |
Het |
| Serpinb13 |
A |
G |
1: 106,926,679 (GRCm39) |
E225G |
probably damaging |
Het |
| Slc25a47 |
T |
C |
12: 108,821,386 (GRCm39) |
L165P |
probably damaging |
Het |
| Slc2a10 |
G |
A |
2: 165,357,197 (GRCm39) |
V286I |
probably benign |
Het |
| Slc39a13 |
G |
T |
2: 90,895,979 (GRCm39) |
T174N |
probably benign |
Het |
| Slc7a13 |
T |
A |
4: 19,839,364 (GRCm39) |
N322K |
probably benign |
Het |
| Stk38 |
T |
C |
17: 29,193,620 (GRCm39) |
T326A |
possibly damaging |
Het |
| Sult1a1 |
T |
C |
7: 126,272,622 (GRCm39) |
M244V |
probably benign |
Het |
| Tas2r144 |
C |
T |
6: 42,192,800 (GRCm39) |
T180I |
probably damaging |
Het |
| Tbc1d12 |
T |
A |
19: 38,887,346 (GRCm39) |
M366K |
probably benign |
Het |
| Terb1 |
T |
C |
8: 105,221,959 (GRCm39) |
I147V |
possibly damaging |
Het |
| Tnik |
T |
C |
3: 28,692,568 (GRCm39) |
Y820H |
probably damaging |
Het |
| Tnxb |
C |
A |
17: 34,901,170 (GRCm39) |
L995I |
possibly damaging |
Het |
| Trim34b |
A |
G |
7: 103,978,794 (GRCm39) |
T14A |
possibly damaging |
Het |
| Urb1 |
T |
C |
16: 90,588,054 (GRCm39) |
E418G |
probably damaging |
Het |
| Vmn1r12 |
T |
A |
6: 57,136,550 (GRCm39) |
C216S |
possibly damaging |
Het |
| Vmn2r90 |
T |
A |
17: 17,924,249 (GRCm39) |
V16E |
possibly damaging |
Het |
| Vps11 |
A |
T |
9: 44,265,803 (GRCm39) |
V492D |
probably damaging |
Het |
| Wdr62 |
A |
C |
7: 29,969,869 (GRCm39) |
|
probably null |
Het |
| Zc3h14 |
T |
A |
12: 98,746,408 (GRCm39) |
M539K |
probably benign |
Het |
| Zfp871 |
A |
T |
17: 32,994,289 (GRCm39) |
H295Q |
probably damaging |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0514:Magi3
|
UTSW |
3 |
103,922,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1964:Magi3
|
UTSW |
3 |
103,927,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2519:Magi3
|
UTSW |
3 |
103,923,081 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6244:Magi3
|
UTSW |
3 |
103,923,013 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Magi3
|
UTSW |
3 |
103,956,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9090:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCACATACTCTGGGCTTGTACTG -3'
(R):5'- AAAAGTCTCTGTGTGGTCAGTG -3'
Sequencing Primer
(F):5'- GTGTCTGTTCACAGCAACAG -3'
(R):5'- GAGGGGTGGACAGGATAATTATAC -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation