Incidental Mutation 'R7583:Clasp2'
| ID |
586895 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clasp2
|
| Ensembl Gene |
ENSMUSG00000033392 |
| Gene Name |
CLIP associating protein 2 |
| Synonyms |
CLASP2alpha, 1500004F14Rik, CLASP2gamma, CLASP2, CLASP2beta, 8030404L10Rik |
| MMRRC Submission |
045666-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7583 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
113570541-113748750 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 113737755 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1043
(D1043G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107469
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000111838]
[ENSMUST00000163895]
[ENSMUST00000166734]
[ENSMUST00000213663]
[ENSMUST00000214522]
[ENSMUST00000215022]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111838
AA Change: D1043G
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000107469
Gene: ENSMUSG00000033392
AA Change: D1043G
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
90 |
323 |
1.17e-8 |
SMART |
|
low complexity region
|
382 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
562 |
572 |
N/A |
INTRINSIC |
|
low complexity region
|
614 |
634 |
N/A |
INTRINSIC |
|
TOG
|
640 |
877 |
2.03e-1 |
SMART |
|
low complexity region
|
995 |
1009 |
N/A |
INTRINSIC |
|
TOG
|
1043 |
1274 |
1.49e-24 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163895
AA Change: D1064G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000128460
Gene: ENSMUSG00000033392
AA Change: D1064G
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
90 |
323 |
1.17e-8 |
SMART |
|
low complexity region
|
382 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
583 |
593 |
N/A |
INTRINSIC |
|
low complexity region
|
635 |
655 |
N/A |
INTRINSIC |
|
TOG
|
661 |
898 |
2.03e-1 |
SMART |
|
low complexity region
|
1016 |
1030 |
N/A |
INTRINSIC |
|
TOG
|
1064 |
1295 |
1.49e-24 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166734
AA Change: D1044G
PolyPhen 2
Score 0.144 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000130201
Gene: ENSMUSG00000033392
AA Change: D1044G
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
90 |
323 |
1.17e-8 |
SMART |
|
low complexity region
|
382 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
472 |
N/A |
INTRINSIC |
|
low complexity region
|
473 |
484 |
N/A |
INTRINSIC |
|
low complexity region
|
562 |
572 |
N/A |
INTRINSIC |
|
low complexity region
|
614 |
634 |
N/A |
INTRINSIC |
|
TOG
|
640 |
878 |
7.51e-1 |
SMART |
|
low complexity region
|
996 |
1010 |
N/A |
INTRINSIC |
|
TOG
|
1044 |
1275 |
1.49e-24 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000213663
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000214522
AA Change: D1061G
PolyPhen 2
Score 0.141 (Sensitivity: 0.92; Specificity: 0.86)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000215022
|
| Meta Mutation Damage Score |
0.0587 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (95/96) |
| MGI Phenotype |
PHENOTYPE: Targeted deletion of this gene leads to impaired formation of stable microtubules in a wound healing assay, and results in a 2-fold reduction of directionally persistent migration in mutant embryonic fibroblasts. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4932414N04Rik |
A |
T |
2: 68,569,670 (GRCm39) |
D462V |
probably damaging |
Het |
| Abcc1 |
T |
C |
16: 14,221,902 (GRCm39) |
W222R |
probably damaging |
Het |
| Adamts13 |
A |
G |
2: 26,863,965 (GRCm39) |
K48E |
probably benign |
Het |
| Adgrd1 |
A |
C |
5: 129,256,652 (GRCm39) |
T674P |
probably benign |
Het |
| Agbl4 |
A |
T |
4: 110,976,150 (GRCm39) |
Y169F |
possibly damaging |
Het |
| Ahnak |
T |
A |
19: 8,983,457 (GRCm39) |
N1580K |
possibly damaging |
Het |
| Angptl8 |
A |
C |
9: 21,747,210 (GRCm39) |
|
probably null |
Het |
| Ap3d1 |
G |
A |
10: 80,545,292 (GRCm39) |
T1053I |
probably benign |
Het |
| Atad2 |
T |
C |
15: 57,990,060 (GRCm39) |
T139A |
probably benign |
Het |
| Bdp1 |
T |
A |
13: 100,186,320 (GRCm39) |
T1711S |
probably damaging |
Het |
| Bod1l |
T |
C |
5: 41,991,133 (GRCm39) |
I141V |
probably damaging |
Het |
| Cavin2 |
A |
T |
1: 51,328,777 (GRCm39) |
N78I |
possibly damaging |
Het |
| Ccnb1 |
T |
C |
13: 100,916,262 (GRCm39) |
H406R |
probably benign |
Het |
| Cd200r4 |
A |
G |
16: 44,653,784 (GRCm39) |
T194A |
probably damaging |
Het |
| Cdt1 |
G |
A |
8: 123,296,995 (GRCm39) |
R263H |
probably damaging |
Het |
| Cep85l |
A |
T |
10: 53,157,450 (GRCm39) |
I751N |
probably damaging |
Het |
| Cmip |
A |
T |
8: 118,181,691 (GRCm39) |
N578I |
probably damaging |
Het |
| Col2a1 |
T |
G |
15: 97,874,065 (GRCm39) |
K1440N |
unknown |
Het |
| Cpne2 |
A |
T |
8: 95,282,209 (GRCm39) |
M252L |
probably benign |
Het |
| Crb2 |
A |
G |
2: 37,680,607 (GRCm39) |
T512A |
probably benign |
Het |
| Csmd1 |
A |
G |
8: 16,048,833 (GRCm39) |
Y2290H |
probably damaging |
Het |
| Ctnnd1 |
A |
T |
2: 84,442,405 (GRCm39) |
D642E |
probably damaging |
Het |
| Ctns |
A |
G |
11: 73,079,296 (GRCm39) |
S141P |
probably benign |
Het |
| Cwh43 |
A |
G |
5: 73,591,632 (GRCm39) |
Q575R |
probably benign |
Het |
| Cyp2b19 |
C |
A |
7: 26,458,489 (GRCm39) |
T68K |
probably damaging |
Het |
| Dcaf6 |
A |
G |
1: 165,160,879 (GRCm39) |
S849P |
probably damaging |
Het |
| Dnm3 |
T |
A |
1: 162,305,343 (GRCm39) |
Q17L |
possibly damaging |
Het |
| Enpp3 |
A |
T |
10: 24,711,990 (GRCm39) |
M1K |
probably null |
Het |
| Fam124a |
T |
A |
14: 62,844,008 (GRCm39) |
C505* |
probably null |
Het |
| Fhip2a |
T |
A |
19: 57,367,034 (GRCm39) |
D192E |
probably benign |
Het |
| Fsip2 |
A |
G |
2: 82,805,585 (GRCm39) |
I635V |
probably benign |
Het |
| Gm5878 |
A |
T |
6: 85,095,682 (GRCm39) |
|
probably null |
Het |
| Gpld1 |
C |
A |
13: 25,159,743 (GRCm39) |
A437D |
probably damaging |
Het |
| Grk5 |
G |
T |
19: 61,071,642 (GRCm39) |
V401L |
possibly damaging |
Het |
| Gucy2g |
A |
T |
19: 55,224,047 (GRCm39) |
L259Q |
probably damaging |
Het |
| Habp2 |
T |
A |
19: 56,300,236 (GRCm39) |
D191E |
probably benign |
Het |
| Helz2 |
T |
A |
2: 180,879,365 (GRCm39) |
H751L |
probably benign |
Het |
| Hgsnat |
A |
G |
8: 26,461,592 (GRCm39) |
|
probably null |
Het |
| Hivep1 |
T |
A |
13: 42,317,716 (GRCm39) |
V2064E |
probably damaging |
Het |
| Ikbke |
C |
T |
1: 131,204,216 (GRCm39) |
A26T |
probably damaging |
Het |
| Ivd |
C |
A |
2: 118,692,612 (GRCm39) |
D37E |
probably damaging |
Het |
| Kif26b |
G |
A |
1: 178,358,010 (GRCm39) |
W40* |
probably null |
Het |
| Klrc2 |
A |
G |
6: 129,636,274 (GRCm39) |
S114P |
probably damaging |
Het |
| Lama1 |
A |
T |
17: 68,068,616 (GRCm39) |
T772S |
|
Het |
| Lamc1 |
T |
A |
1: 153,118,978 (GRCm39) |
K880N |
possibly damaging |
Het |
| Lmf1 |
G |
A |
17: 25,874,423 (GRCm39) |
D12N |
|
Het |
| Lpin2 |
G |
T |
17: 71,538,391 (GRCm39) |
E384* |
probably null |
Het |
| Lrrc23 |
T |
C |
6: 124,756,541 (GRCm39) |
|
probably benign |
Het |
| Lrrc31 |
T |
C |
3: 30,745,248 (GRCm39) |
|
probably null |
Het |
| Luc7l2 |
A |
G |
6: 38,528,820 (GRCm39) |
Q13R |
probably damaging |
Het |
| Ly6c1 |
G |
T |
15: 74,920,346 (GRCm39) |
H5Q |
probably damaging |
Het |
| Lyst |
A |
T |
13: 13,810,472 (GRCm39) |
H714L |
probably damaging |
Het |
| Man2a2 |
C |
T |
7: 80,016,692 (GRCm39) |
R374H |
probably damaging |
Het |
| Mchr1 |
A |
T |
15: 81,121,642 (GRCm39) |
T131S |
probably benign |
Het |
| Msto1 |
T |
C |
3: 88,820,236 (GRCm39) |
|
probably null |
Het |
| Myh1 |
C |
T |
11: 67,111,739 (GRCm39) |
T1698I |
probably benign |
Het |
| Ncapd3 |
G |
T |
9: 26,983,144 (GRCm39) |
C964F |
probably damaging |
Het |
| Nefh |
T |
C |
11: 4,891,089 (GRCm39) |
E510G |
probably damaging |
Het |
| Or10g3b |
T |
C |
14: 52,587,360 (GRCm39) |
T48A |
possibly damaging |
Het |
| Or13a24 |
A |
G |
7: 140,154,123 (GRCm39) |
E19G |
probably benign |
Het |
| Or1b1 |
A |
T |
2: 36,995,539 (GRCm39) |
L41* |
probably null |
Het |
| Or1q1 |
A |
C |
2: 36,887,092 (GRCm39) |
K90T |
probably damaging |
Het |
| Or4a73 |
A |
T |
2: 89,421,095 (GRCm39) |
Y121* |
probably null |
Het |
| P4ha1 |
T |
A |
10: 59,205,462 (GRCm39) |
S497R |
probably benign |
Het |
| Palb2 |
T |
C |
7: 121,726,565 (GRCm39) |
D435G |
probably benign |
Het |
| Papola |
C |
T |
12: 105,777,304 (GRCm39) |
P282L |
probably damaging |
Het |
| Pcdhgb1 |
A |
G |
18: 37,815,377 (GRCm39) |
R623G |
probably damaging |
Het |
| Pcolce |
T |
G |
5: 137,605,707 (GRCm39) |
K229Q |
probably benign |
Het |
| Pkhd1l1 |
T |
C |
15: 44,431,760 (GRCm39) |
|
probably null |
Het |
| Ppp6r3 |
T |
A |
19: 3,540,790 (GRCm39) |
T443S |
probably benign |
Het |
| Pramel58 |
A |
T |
5: 94,830,753 (GRCm39) |
T84S |
possibly damaging |
Het |
| Psg20 |
T |
A |
7: 18,416,408 (GRCm39) |
D236V |
probably damaging |
Het |
| Ptgr2 |
T |
G |
12: 84,355,179 (GRCm39) |
S304R |
probably damaging |
Het |
| Ptpn22 |
A |
T |
3: 103,809,430 (GRCm39) |
D681V |
probably benign |
Het |
| Rab3gap1 |
T |
C |
1: 127,858,612 (GRCm39) |
S574P |
probably benign |
Het |
| Slc36a1 |
A |
G |
11: 55,104,754 (GRCm39) |
|
probably null |
Het |
| Slc9a5 |
A |
G |
8: 106,089,904 (GRCm39) |
S621G |
possibly damaging |
Het |
| Sntg1 |
A |
G |
1: 8,515,249 (GRCm39) |
|
probably null |
Het |
| Snx17 |
A |
G |
5: 31,353,877 (GRCm39) |
N222D |
possibly damaging |
Het |
| Spata19 |
G |
T |
9: 27,311,729 (GRCm39) |
S116I |
possibly damaging |
Het |
| Spn |
G |
A |
7: 126,736,234 (GRCm39) |
A91V |
probably damaging |
Het |
| Srrm3 |
T |
C |
5: 135,881,135 (GRCm39) |
V145A |
probably benign |
Het |
| St7 |
A |
T |
6: 17,942,753 (GRCm39) |
T575S |
possibly damaging |
Het |
| Taf2 |
A |
T |
15: 54,928,072 (GRCm39) |
Y110* |
probably null |
Het |
| Tcf20 |
T |
C |
15: 82,739,477 (GRCm39) |
E658G |
possibly damaging |
Het |
| Tdrd6 |
G |
T |
17: 43,935,129 (GRCm39) |
A1973E |
probably benign |
Het |
| Tg |
T |
G |
15: 66,636,267 (GRCm39) |
L2237W |
probably damaging |
Het |
| Ticrr |
C |
A |
7: 79,346,487 (GRCm39) |
Y1882* |
probably null |
Het |
| Trim45 |
T |
A |
3: 100,832,339 (GRCm39) |
C191S |
probably damaging |
Het |
| Upf3a |
G |
A |
8: 13,835,889 (GRCm39) |
|
probably null |
Het |
| Vmn2r42 |
A |
T |
7: 8,197,740 (GRCm39) |
L293* |
probably null |
Het |
| Vmn2r62 |
T |
A |
7: 42,437,466 (GRCm39) |
Q339H |
possibly damaging |
Het |
| Wdr24 |
A |
T |
17: 26,044,804 (GRCm39) |
R220W |
probably null |
Het |
| Wdr5 |
T |
A |
2: 27,408,787 (GRCm39) |
S22T |
probably benign |
Het |
| Zfp37 |
G |
A |
4: 62,110,253 (GRCm39) |
|
probably benign |
Het |
| Zfp735 |
A |
T |
11: 73,601,933 (GRCm39) |
L292F |
possibly damaging |
Het |
| Zfp985 |
T |
A |
4: 147,667,946 (GRCm39) |
C271* |
probably null |
Het |
| Zranb1 |
G |
A |
7: 132,585,625 (GRCm39) |
R691Q |
probably benign |
Het |
|
| Other mutations in Clasp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00772:Clasp2
|
APN |
9 |
113,735,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL00885:Clasp2
|
APN |
9 |
113,740,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01314:Clasp2
|
APN |
9 |
113,735,195 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01344:Clasp2
|
APN |
9 |
113,642,360 (GRCm39) |
splice site |
probably null |
|
|
IGL01567:Clasp2
|
APN |
9 |
113,709,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02238:Clasp2
|
APN |
9 |
113,709,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02299:Clasp2
|
APN |
9 |
113,709,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02323:Clasp2
|
APN |
9 |
113,697,794 (GRCm39) |
splice site |
probably benign |
|
|
IGL02635:Clasp2
|
APN |
9 |
113,737,910 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02645:Clasp2
|
APN |
9 |
113,719,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02976:Clasp2
|
APN |
9 |
113,735,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03190:Clasp2
|
APN |
9 |
113,673,208 (GRCm39) |
nonsense |
probably null |
|
|
IGL03219:Clasp2
|
APN |
9 |
113,677,545 (GRCm39) |
splice site |
probably benign |
|
|
PIT4810001:Clasp2
|
UTSW |
9 |
113,735,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0067:Clasp2
|
UTSW |
9 |
113,689,209 (GRCm39) |
splice site |
probably benign |
|
|
R0067:Clasp2
|
UTSW |
9 |
113,689,209 (GRCm39) |
splice site |
probably benign |
|
|
R0421:Clasp2
|
UTSW |
9 |
113,683,370 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0432:Clasp2
|
UTSW |
9 |
113,738,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0458:Clasp2
|
UTSW |
9 |
113,735,292 (GRCm39) |
splice site |
probably null |
|
|
R0865:Clasp2
|
UTSW |
9 |
113,740,568 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R0972:Clasp2
|
UTSW |
9 |
113,676,773 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1037:Clasp2
|
UTSW |
9 |
113,725,702 (GRCm39) |
splice site |
probably benign |
|
|
R1925:Clasp2
|
UTSW |
9 |
113,735,265 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2015:Clasp2
|
UTSW |
9 |
113,740,568 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R2066:Clasp2
|
UTSW |
9 |
113,735,225 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2330:Clasp2
|
UTSW |
9 |
113,705,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2568:Clasp2
|
UTSW |
9 |
113,707,832 (GRCm39) |
missense |
probably benign |
|
|
R3011:Clasp2
|
UTSW |
9 |
113,730,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3879:Clasp2
|
UTSW |
9 |
113,719,029 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3915:Clasp2
|
UTSW |
9 |
113,737,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3928:Clasp2
|
UTSW |
9 |
113,735,173 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4323:Clasp2
|
UTSW |
9 |
113,719,027 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4571:Clasp2
|
UTSW |
9 |
113,676,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Clasp2
|
UTSW |
9 |
113,732,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5445:Clasp2
|
UTSW |
9 |
113,733,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5564:Clasp2
|
UTSW |
9 |
113,641,836 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5697:Clasp2
|
UTSW |
9 |
113,689,190 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5780:Clasp2
|
UTSW |
9 |
113,679,220 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5787:Clasp2
|
UTSW |
9 |
113,691,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6011:Clasp2
|
UTSW |
9 |
113,705,315 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6026:Clasp2
|
UTSW |
9 |
113,740,646 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6090:Clasp2
|
UTSW |
9 |
113,681,803 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6262:Clasp2
|
UTSW |
9 |
113,705,420 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6427:Clasp2
|
UTSW |
9 |
113,721,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6464:Clasp2
|
UTSW |
9 |
113,602,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6586:Clasp2
|
UTSW |
9 |
113,642,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6628:Clasp2
|
UTSW |
9 |
113,725,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6745:Clasp2
|
UTSW |
9 |
113,704,338 (GRCm39) |
nonsense |
probably null |
|
|
R7032:Clasp2
|
UTSW |
9 |
113,683,391 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7165:Clasp2
|
UTSW |
9 |
113,615,467 (GRCm39) |
splice site |
probably null |
|
|
R7221:Clasp2
|
UTSW |
9 |
113,681,825 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7336:Clasp2
|
UTSW |
9 |
113,705,421 (GRCm39) |
splice site |
probably null |
|
|
R7774:Clasp2
|
UTSW |
9 |
113,677,804 (GRCm39) |
splice site |
probably null |
|
|
R7895:Clasp2
|
UTSW |
9 |
113,733,016 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8084:Clasp2
|
UTSW |
9 |
113,676,823 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8109:Clasp2
|
UTSW |
9 |
113,740,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8171:Clasp2
|
UTSW |
9 |
113,732,974 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8230:Clasp2
|
UTSW |
9 |
113,721,482 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8810:Clasp2
|
UTSW |
9 |
113,728,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8879:Clasp2
|
UTSW |
9 |
113,602,773 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8888:Clasp2
|
UTSW |
9 |
113,732,936 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8889:Clasp2
|
UTSW |
9 |
113,709,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8892:Clasp2
|
UTSW |
9 |
113,709,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8922:Clasp2
|
UTSW |
9 |
113,725,728 (GRCm39) |
nonsense |
probably null |
|
|
R9042:Clasp2
|
UTSW |
9 |
113,735,065 (GRCm39) |
missense |
probably benign |
|
|
R9195:Clasp2
|
UTSW |
9 |
113,671,045 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9355:Clasp2
|
UTSW |
9 |
113,664,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9481:Clasp2
|
UTSW |
9 |
113,670,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Clasp2
|
UTSW |
9 |
113,737,866 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9523:Clasp2
|
UTSW |
9 |
113,705,372 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Clasp2
|
UTSW |
9 |
113,740,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9653:Clasp2
|
UTSW |
9 |
113,670,993 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9699:Clasp2
|
UTSW |
9 |
113,738,614 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9738:Clasp2
|
UTSW |
9 |
113,590,665 (GRCm39) |
nonsense |
probably null |
|
|
R9775:Clasp2
|
UTSW |
9 |
113,725,740 (GRCm39) |
missense |
probably benign |
|
|
X0022:Clasp2
|
UTSW |
9 |
113,681,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clasp2
|
UTSW |
9 |
113,599,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clasp2
|
UTSW |
9 |
113,737,863 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACAGCATTTCAAGGAGATGGTAC -3'
(R):5'- TTATCCCCAAGGGTCTCAAGC -3'
Sequencing Primer
(F):5'- TAGGAGTGACACGCTCTGG -3'
(R):5'- TATCCCCAAGGGTCTCAAGCAATAAC -3'
|
| Posted On |
2019-10-24 |
Incidental Mutation