Incidental Mutation 'R9182:Myh13'
| ID |
697130 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh13
|
| Ensembl Gene |
ENSMUSG00000060180 |
| Gene Name |
myosin, heavy polypeptide 13, skeletal muscle |
| Synonyms |
EO Myosin, MyHC-eo, extraocular myosin |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.157)
|
| Stock # |
R9182 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
67217929-67262413 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 67228579 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 373
(E373G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000080584
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000081911]
[ENSMUST00000108684]
[ENSMUST00000180845]
|
| AlphaFold |
B1AR69 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000081911
AA Change: E373G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000080584
Gene: ENSMUSG00000060180
AA Change: E373G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
74 |
8e-13 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
Pfam:Myosin_tail_1
|
847 |
1928 |
4.6e-159 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108684
AA Change: E373G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000104324
Gene: ENSMUSG00000060180
AA Change: E373G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000180845
AA Change: E373G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000137731
Gene: ENSMUSG00000060180
AA Change: E373G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
35 |
76 |
2.8e-14 |
PFAM |
|
MYSc
|
80 |
783 |
N/A |
SMART |
|
IQ
|
784 |
806 |
4.6e-1 |
SMART |
|
low complexity region
|
847 |
858 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
940 |
N/A |
INTRINSIC |
|
Pfam:Myosin_tail_1
|
1072 |
1930 |
N/A |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
100% (99/99) |
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2900026A02Rik |
A |
T |
5: 113,243,473 (GRCm39) |
M190K |
probably damaging |
Het |
| 4931406B18Rik |
A |
G |
7: 43,153,640 (GRCm39) |
W3R |
probably damaging |
Het |
| Acap3 |
T |
C |
4: 155,989,892 (GRCm39) |
L720P |
probably damaging |
Het |
| Actc1 |
T |
C |
2: 113,882,494 (GRCm39) |
T7A |
probably benign |
Het |
| Angpt2 |
T |
A |
8: 18,760,658 (GRCm39) |
|
probably null |
Het |
| Babam2 |
T |
A |
5: 32,058,401 (GRCm39) |
D228E |
possibly damaging |
Het |
| Ccar1 |
G |
A |
10: 62,621,347 (GRCm39) |
L34F |
probably damaging |
Het |
| Ccdc83 |
T |
C |
7: 89,886,102 (GRCm39) |
D219G |
probably damaging |
Het |
| Cct2 |
A |
G |
10: 116,892,025 (GRCm39) |
V341A |
probably benign |
Het |
| Cdc20b |
G |
A |
13: 113,208,503 (GRCm39) |
|
probably null |
Het |
| Chd7 |
T |
A |
4: 8,838,737 (GRCm39) |
L1312Q |
probably damaging |
Het |
| Cltc |
G |
A |
11: 86,595,982 (GRCm39) |
T1252I |
probably damaging |
Het |
| Cnpy1 |
G |
T |
5: 28,450,799 (GRCm39) |
D2E |
possibly damaging |
Het |
| Crat |
C |
T |
2: 30,298,085 (GRCm39) |
V205M |
probably damaging |
Het |
| Cspg4b |
A |
G |
13: 113,457,358 (GRCm39) |
N1135D |
|
Het |
| Dgkb |
T |
C |
12: 38,216,776 (GRCm39) |
|
probably null |
Het |
| Dglucy |
T |
C |
12: 100,811,028 (GRCm39) |
V254A |
possibly damaging |
Het |
| Disp3 |
A |
G |
4: 148,354,841 (GRCm39) |
S392P |
probably damaging |
Het |
| Dlx6 |
A |
T |
6: 6,863,456 (GRCm39) |
Q26L |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,684,351 (GRCm39) |
D258G |
probably damaging |
Het |
| Dnah6 |
A |
T |
6: 73,121,688 (GRCm39) |
Y1431* |
probably null |
Het |
| Dnah7b |
T |
C |
1: 46,330,038 (GRCm39) |
I3294T |
probably benign |
Het |
| Dnai2 |
A |
G |
11: 114,623,839 (GRCm39) |
N34S |
probably benign |
Het |
| Dock2 |
T |
C |
11: 34,260,398 (GRCm39) |
K981R |
possibly damaging |
Het |
| Entpd8 |
T |
C |
2: 24,971,931 (GRCm39) |
I33T |
probably benign |
Het |
| Eppk1 |
A |
G |
15: 75,995,453 (GRCm39) |
L476P |
probably benign |
Het |
| Etv1 |
T |
A |
12: 38,830,716 (GRCm39) |
|
probably null |
Het |
| Fads2b |
T |
C |
2: 85,330,581 (GRCm39) |
H242R |
probably benign |
Het |
| Fam193a |
T |
A |
5: 34,623,361 (GRCm39) |
N1316K |
possibly damaging |
Het |
| Fkbp4 |
T |
C |
6: 128,415,382 (GRCm39) |
E31G |
probably benign |
Het |
| Fnbp1l |
C |
T |
3: 122,363,345 (GRCm39) |
D81N |
probably damaging |
Het |
| Fstl4 |
T |
C |
11: 53,024,905 (GRCm39) |
V259A |
probably damaging |
Het |
| Glipr1l1 |
T |
C |
10: 111,912,056 (GRCm39) |
S197P |
probably damaging |
Het |
| Gprin3 |
A |
T |
6: 59,331,197 (GRCm39) |
M370K |
probably benign |
Het |
| Gsc |
G |
T |
12: 104,439,120 (GRCm39) |
Y85* |
probably null |
Het |
| Gys2 |
T |
G |
6: 142,391,735 (GRCm39) |
Y509S |
probably damaging |
Het |
| Gys2 |
T |
C |
6: 142,406,978 (GRCm39) |
N126S |
possibly damaging |
Het |
| Hmcn1 |
A |
T |
1: 150,488,405 (GRCm39) |
W4292R |
probably damaging |
Het |
| Hmcn1 |
C |
A |
1: 150,500,337 (GRCm39) |
E3952* |
probably null |
Het |
| Hsd3b9 |
C |
T |
3: 98,354,005 (GRCm39) |
A165T |
possibly damaging |
Het |
| Htr1f |
T |
C |
16: 64,746,825 (GRCm39) |
M156V |
probably benign |
Het |
| Il21r |
G |
A |
7: 125,228,213 (GRCm39) |
G228E |
probably benign |
Het |
| Kat6b |
C |
T |
14: 21,567,187 (GRCm39) |
S82L |
probably benign |
Het |
| Kntc1 |
T |
A |
5: 123,940,355 (GRCm39) |
L1651Q |
probably damaging |
Het |
| Lipi |
G |
T |
16: 75,357,673 (GRCm39) |
Y297* |
probably null |
Het |
| Mapre3 |
T |
C |
5: 31,022,016 (GRCm39) |
S190P |
possibly damaging |
Het |
| Mmp8 |
T |
A |
9: 7,567,467 (GRCm39) |
Y442* |
probably null |
Het |
| Mmut |
A |
G |
17: 41,252,310 (GRCm39) |
E284G |
probably damaging |
Het |
| Mt3 |
G |
A |
8: 94,880,615 (GRCm39) |
E62K |
unknown |
Het |
| Myh7 |
T |
C |
14: 55,226,374 (GRCm39) |
Y422C |
probably damaging |
Het |
| Nalcn |
A |
G |
14: 123,834,016 (GRCm39) |
V53A |
probably damaging |
Het |
| Nucb2 |
A |
G |
7: 116,121,070 (GRCm39) |
|
probably null |
Het |
| Opn5 |
A |
T |
17: 42,903,890 (GRCm39) |
H148Q |
probably damaging |
Het |
| Or13a23-ps1 |
A |
T |
7: 140,118,782 (GRCm39) |
L117F |
probably benign |
Het |
| Or51h1 |
A |
T |
7: 102,308,927 (GRCm39) |
I300L |
probably damaging |
Het |
| Or51v14 |
T |
C |
7: 103,261,063 (GRCm39) |
K166E |
possibly damaging |
Het |
| Or6b1 |
A |
T |
6: 42,815,010 (GRCm39) |
N65I |
probably benign |
Het |
| Or7g16 |
G |
T |
9: 18,726,742 (GRCm39) |
Q283K |
probably damaging |
Het |
| Or8b56 |
C |
A |
9: 38,739,172 (GRCm39) |
H56N |
probably damaging |
Het |
| Osmr |
T |
A |
15: 6,850,569 (GRCm39) |
D679V |
probably damaging |
Het |
| Pde4dip |
T |
C |
3: 97,602,314 (GRCm39) |
D2305G |
probably benign |
Het |
| Pdgfrl |
A |
T |
8: 41,429,996 (GRCm39) |
Q121L |
probably damaging |
Het |
| Pls1 |
C |
A |
9: 95,658,811 (GRCm39) |
V226F |
probably damaging |
Het |
| Plxnd1 |
T |
A |
6: 115,970,746 (GRCm39) |
I341F |
probably damaging |
Het |
| Ppfia2 |
T |
A |
10: 106,763,640 (GRCm39) |
M1211K |
probably benign |
Het |
| Ppfibp2 |
T |
A |
7: 107,308,053 (GRCm39) |
Y229N |
possibly damaging |
Het |
| Prss53 |
A |
G |
7: 127,487,554 (GRCm39) |
S266P |
probably benign |
Het |
| Pycr2 |
C |
T |
1: 180,734,397 (GRCm39) |
Q226* |
probably null |
Het |
| Rad50 |
T |
C |
11: 53,583,590 (GRCm39) |
H397R |
probably benign |
Het |
| Raf1 |
T |
C |
6: 115,600,440 (GRCm39) |
E393G |
probably damaging |
Het |
| Reln |
T |
C |
5: 22,106,617 (GRCm39) |
D3251G |
probably benign |
Het |
| Robo4 |
A |
T |
9: 37,313,206 (GRCm39) |
|
probably benign |
Het |
| Sbf1 |
A |
T |
15: 89,173,806 (GRCm39) |
|
probably null |
Het |
| Serpinb6a |
T |
C |
13: 34,109,360 (GRCm39) |
D145G |
probably damaging |
Het |
| Setx |
T |
A |
2: 29,061,299 (GRCm39) |
M2236K |
probably damaging |
Het |
| Sgms1 |
A |
G |
19: 32,101,758 (GRCm39) |
V416A |
probably benign |
Het |
| Six5 |
T |
G |
7: 18,830,932 (GRCm39) |
S520A |
probably benign |
Het |
| Sox5 |
T |
A |
6: 143,779,118 (GRCm39) |
I722F |
possibly damaging |
Het |
| Spag17 |
T |
G |
3: 99,966,158 (GRCm39) |
I1147S |
possibly damaging |
Het |
| Spice1 |
C |
T |
16: 44,206,065 (GRCm39) |
T842I |
possibly damaging |
Het |
| Ssbp2 |
A |
G |
13: 91,848,800 (GRCm39) |
T358A |
probably damaging |
Het |
| Taok3 |
T |
C |
5: 117,355,307 (GRCm39) |
|
probably null |
Het |
| Tbc1d2b |
C |
A |
9: 90,152,652 (GRCm39) |
C38F |
probably damaging |
Het |
| Tecrl |
C |
A |
5: 83,457,049 (GRCm39) |
|
probably null |
Het |
| Tgm7 |
T |
C |
2: 120,926,980 (GRCm39) |
N390D |
probably benign |
Het |
| Thsd4 |
T |
G |
9: 59,894,649 (GRCm39) |
M770L |
probably benign |
Het |
| Tmod2 |
C |
A |
9: 75,504,624 (GRCm39) |
|
probably benign |
Het |
| Tnks |
A |
G |
8: 35,308,905 (GRCm39) |
|
probably null |
Het |
| Tox3 |
T |
C |
8: 90,984,507 (GRCm39) |
N224S |
probably benign |
Het |
| Trappc10 |
C |
T |
10: 78,050,464 (GRCm39) |
E326K |
probably damaging |
Het |
| Usp16 |
T |
A |
16: 87,276,542 (GRCm39) |
F627I |
probably benign |
Het |
| Vcam1 |
T |
C |
3: 115,911,004 (GRCm39) |
I465V |
probably benign |
Het |
| Vmn1r128 |
T |
C |
7: 21,083,683 (GRCm39) |
I129T |
possibly damaging |
Het |
| Vmn1r217 |
T |
A |
13: 23,298,495 (GRCm39) |
I136L |
probably benign |
Het |
| Vmn2r2 |
A |
T |
3: 64,044,802 (GRCm39) |
C115S |
probably damaging |
Het |
| Vmn2r85 |
A |
C |
10: 130,265,350 (GRCm39) |
S44R |
probably benign |
Het |
| Wasf3 |
T |
A |
5: 146,403,635 (GRCm39) |
Y248* |
probably null |
Het |
| Yipf5 |
A |
T |
18: 40,343,851 (GRCm39) |
L127M |
probably damaging |
Het |
| Zbp1 |
G |
T |
2: 173,050,933 (GRCm39) |
C312* |
probably null |
Het |
| Zfp423 |
A |
T |
8: 88,508,742 (GRCm39) |
F534Y |
probably damaging |
Het |
| Zfp69 |
T |
G |
4: 120,792,308 (GRCm39) |
Y156S |
probably damaging |
Het |
| Zmat4 |
A |
G |
8: 24,419,226 (GRCm39) |
N155S |
probably damaging |
Het |
|
| Other mutations in Myh13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Myh13
|
APN |
11 |
67,233,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00808:Myh13
|
APN |
11 |
67,225,830 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00822:Myh13
|
APN |
11 |
67,252,154 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL00823:Myh13
|
APN |
11 |
67,246,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00945:Myh13
|
APN |
11 |
67,238,832 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL01414:Myh13
|
APN |
11 |
67,233,298 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01482:Myh13
|
APN |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
IGL01523:Myh13
|
APN |
11 |
67,238,769 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01723:Myh13
|
APN |
11 |
67,260,045 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01997:Myh13
|
APN |
11 |
67,257,992 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02369:Myh13
|
APN |
11 |
67,251,100 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02478:Myh13
|
APN |
11 |
67,260,204 (GRCm39) |
missense |
probably benign |
|
|
IGL02663:Myh13
|
APN |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL02851:Myh13
|
APN |
11 |
67,239,742 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02863:Myh13
|
APN |
11 |
67,223,367 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02929:Myh13
|
APN |
11 |
67,257,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02979:Myh13
|
APN |
11 |
67,225,788 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL03065:Myh13
|
APN |
11 |
67,235,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03214:Myh13
|
APN |
11 |
67,244,411 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL03223:Myh13
|
APN |
11 |
67,241,068 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL03231:Myh13
|
APN |
11 |
67,242,817 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03407:Myh13
|
APN |
11 |
67,242,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Myh13
|
UTSW |
11 |
67,242,777 (GRCm39) |
splice site |
probably benign |
|
|
P0042:Myh13
|
UTSW |
11 |
67,225,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0047:Myh13
|
UTSW |
11 |
67,258,063 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0379:Myh13
|
UTSW |
11 |
67,260,121 (GRCm39) |
unclassified |
probably benign |
|
|
R0496:Myh13
|
UTSW |
11 |
67,239,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0584:Myh13
|
UTSW |
11 |
67,251,200 (GRCm39) |
nonsense |
probably null |
|
|
R0595:Myh13
|
UTSW |
11 |
67,235,672 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0621:Myh13
|
UTSW |
11 |
67,232,058 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0834:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R0893:Myh13
|
UTSW |
11 |
67,225,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0964:Myh13
|
UTSW |
11 |
67,235,828 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0974:Myh13
|
UTSW |
11 |
67,223,346 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1028:Myh13
|
UTSW |
11 |
67,247,007 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R1112:Myh13
|
UTSW |
11 |
67,245,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1283:Myh13
|
UTSW |
11 |
67,261,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1288:Myh13
|
UTSW |
11 |
67,244,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1386:Myh13
|
UTSW |
11 |
67,261,776 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1457:Myh13
|
UTSW |
11 |
67,221,872 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1503:Myh13
|
UTSW |
11 |
67,244,500 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1574:Myh13
|
UTSW |
11 |
67,253,407 (GRCm39) |
unclassified |
probably benign |
|
|
R1673:Myh13
|
UTSW |
11 |
67,242,945 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1693:Myh13
|
UTSW |
11 |
67,232,310 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1763:Myh13
|
UTSW |
11 |
67,225,402 (GRCm39) |
missense |
probably benign |
|
|
R2029:Myh13
|
UTSW |
11 |
67,252,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2030:Myh13
|
UTSW |
11 |
67,241,064 (GRCm39) |
missense |
probably benign |
|
|
R2247:Myh13
|
UTSW |
11 |
67,225,384 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2393:Myh13
|
UTSW |
11 |
67,231,184 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2395:Myh13
|
UTSW |
11 |
67,255,748 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2884:Myh13
|
UTSW |
11 |
67,228,469 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3696:Myh13
|
UTSW |
11 |
67,235,870 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R3786:Myh13
|
UTSW |
11 |
67,218,014 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Myh13
|
UTSW |
11 |
67,249,020 (GRCm39) |
missense |
probably benign |
0.26 |
|
R3918:Myh13
|
UTSW |
11 |
67,220,064 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4061:Myh13
|
UTSW |
11 |
67,221,715 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4160:Myh13
|
UTSW |
11 |
67,255,636 (GRCm39) |
intron |
probably benign |
|
|
R4183:Myh13
|
UTSW |
11 |
67,240,436 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4392:Myh13
|
UTSW |
11 |
67,235,707 (GRCm39) |
splice site |
probably null |
|
|
R4639:Myh13
|
UTSW |
11 |
67,232,377 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4670:Myh13
|
UTSW |
11 |
67,255,564 (GRCm39) |
nonsense |
probably null |
|
|
R4783:Myh13
|
UTSW |
11 |
67,232,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4877:Myh13
|
UTSW |
11 |
67,228,477 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5250:Myh13
|
UTSW |
11 |
67,218,085 (GRCm39) |
nonsense |
probably null |
|
|
R5278:Myh13
|
UTSW |
11 |
67,225,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5371:Myh13
|
UTSW |
11 |
67,235,616 (GRCm39) |
splice site |
probably null |
|
|
R5479:Myh13
|
UTSW |
11 |
67,239,648 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5510:Myh13
|
UTSW |
11 |
67,228,549 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5690:Myh13
|
UTSW |
11 |
67,220,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5797:Myh13
|
UTSW |
11 |
67,225,828 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5823:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Myh13
|
UTSW |
11 |
67,244,484 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6041:Myh13
|
UTSW |
11 |
67,255,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Myh13
|
UTSW |
11 |
67,245,588 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6244:Myh13
|
UTSW |
11 |
67,253,327 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6454:Myh13
|
UTSW |
11 |
67,241,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6617:Myh13
|
UTSW |
11 |
67,252,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6707:Myh13
|
UTSW |
11 |
67,241,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6747:Myh13
|
UTSW |
11 |
67,241,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6823:Myh13
|
UTSW |
11 |
67,246,984 (GRCm39) |
missense |
probably benign |
|
|
R6911:Myh13
|
UTSW |
11 |
67,245,753 (GRCm39) |
nonsense |
probably null |
|
|
R6997:Myh13
|
UTSW |
11 |
67,217,980 (GRCm39) |
nonsense |
probably null |
|
|
R7033:Myh13
|
UTSW |
11 |
67,260,142 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7145:Myh13
|
UTSW |
11 |
67,245,566 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7232:Myh13
|
UTSW |
11 |
67,239,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Myh13
|
UTSW |
11 |
67,223,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Myh13
|
UTSW |
11 |
67,255,286 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7474:Myh13
|
UTSW |
11 |
67,258,537 (GRCm39) |
missense |
|
|
|
R7474:Myh13
|
UTSW |
11 |
67,217,990 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7766:Myh13
|
UTSW |
11 |
67,249,155 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7809:Myh13
|
UTSW |
11 |
67,241,167 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7813:Myh13
|
UTSW |
11 |
67,218,056 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7953:Myh13
|
UTSW |
11 |
67,231,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Myh13
|
UTSW |
11 |
67,225,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Myh13
|
UTSW |
11 |
67,241,113 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8434:Myh13
|
UTSW |
11 |
67,254,011 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8490:Myh13
|
UTSW |
11 |
67,255,351 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8676:Myh13
|
UTSW |
11 |
67,233,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8681:Myh13
|
UTSW |
11 |
67,242,960 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8777:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8777-TAIL:Myh13
|
UTSW |
11 |
67,252,161 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8965:Myh13
|
UTSW |
11 |
67,255,432 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9088:Myh13
|
UTSW |
11 |
67,242,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9151:Myh13
|
UTSW |
11 |
67,252,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Myh13
|
UTSW |
11 |
67,253,318 (GRCm39) |
missense |
probably benign |
|
|
R9332:Myh13
|
UTSW |
11 |
67,254,109 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9393:Myh13
|
UTSW |
11 |
67,242,894 (GRCm39) |
missense |
probably benign |
|
|
R9446:Myh13
|
UTSW |
11 |
67,255,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9474:Myh13
|
UTSW |
11 |
67,255,712 (GRCm39) |
missense |
|
|
|
R9690:Myh13
|
UTSW |
11 |
67,249,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9761:Myh13
|
UTSW |
11 |
67,251,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9778:Myh13
|
UTSW |
11 |
67,249,016 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Myh13
|
UTSW |
11 |
67,220,121 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,255,417 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Myh13
|
UTSW |
11 |
67,241,278 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCACTCGTGTGAGCAAATG -3'
(R):5'- AGGCATGTCTTGAGAGTAGATGATG -3'
Sequencing Primer
(F):5'- CAAATGCTGTCTCGTCTGATACACAG -3'
(R):5'- TGAGAGTAGATGATGATTTGACACC -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation